Mus musculus

0 known processes

Hes2

hairy and enhancer of split 2 (Drosophila)

(Aliases: HES-2)

Hes2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cellular ketone metabolic process GO:0042180 84 0.811
regulation of cellular amino acid metabolic process GO:0006521 5 0.629
pancreatic pp cell fate commitment GO:0003329 2 0.574
regionalization GO:0003002 337 0.550
Mouse Worm Fly
regulation of cellular ketone metabolic process GO:0010565 66 0.535
cellular amine metabolic process GO:0044106 44 0.475
developmental maturation GO:0021700 193 0.405
Mouse
gland development GO:0048732 330 0.385
Mouse
pancreatic a cell fate commitment GO:0003326 2 0.382
myeloid cell differentiation GO:0030099 233 0.376
regulation of cellular amine metabolic process GO:0033238 20 0.332
pancreatic pp cell differentiation GO:0003312 2 0.330
cardiac right ventricle formation GO:0003219 3 0.322
smoothened signaling pathway GO:0007224 105 0.311
Mouse
skeletal system development GO:0001501 356 0.271
Mouse
chemotaxis GO:0006935 247 0.261
regulation of cardioblast differentiation GO:0051890 3 0.250
glial cell differentiation GO:0010001 131 0.249
Mouse
cell fate commitment GO:0045165 210 0.219
Mouse Worm Fly
peptidyl amino acid modification GO:0018193 336 0.217
Mouse
endocrine system development GO:0035270 98 0.215
Mouse
regulation of myeloid cell differentiation GO:0045637 96 0.210
central nervous system neuron differentiation GO:0021953 162 0.195
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.192
spinal cord oligodendrocyte cell fate specification GO:0021530 3 0.189
g protein coupled receptor signaling pathway GO:0007186 243 0.188
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process GO:2000763 1 0.184
cell type specific apoptotic process GO:0097285 268 0.181
cerebellum development GO:0021549 77 0.181
neuron migration GO:0001764 122 0.180
positive regulation of transcription via serum response element binding GO:0010735 1 0.179
urogenital system development GO:0001655 261 0.175
Mouse
hemangioblast cell differentiation GO:0060217 1 0.173
positive regulation of cell development GO:0010720 237 0.171
Mouse Fly
cellular amino acid metabolic process GO:0006520 103 0.168
negative regulation of cell proliferation GO:0008285 296 0.167
Mouse
kidney development GO:0001822 213 0.165
Mouse
ventricular cardiac myofibril assembly GO:0055005 3 0.164
monocarboxylic acid metabolic process GO:0032787 191 0.161
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000802 1 0.159
somitogenesis GO:0001756 69 0.157
Mouse
regulation of neuron apoptotic process GO:0043523 122 0.157
cardiac neural crest cell migration involved in outflow tract morphogenesis GO:0003253 3 0.155
muscle cell differentiation GO:0042692 261 0.153
Mouse
neuron death GO:0070997 154 0.153
mesenchymal cell differentiation GO:0048762 107 0.147
Mouse
regulation of neuron death GO:1901214 134 0.143
amine metabolic process GO:0009308 45 0.140
oligodendrocyte differentiation GO:0048709 53 0.140
Mouse
spinal cord oligodendrocyte cell differentiation GO:0021529 3 0.139
spleen development GO:0048536 39 0.138
negative regulation of intracellular signal transduction GO:1902532 167 0.134
metencephalon development GO:0022037 89 0.134
neuron apoptotic process GO:0051402 142 0.131
cell growth GO:0016049 130 0.128
b cell differentiation GO:0030183 78 0.127
mesenchyme development GO:0060485 152 0.124
Mouse
neuron fate specification GO:0048665 30 0.124
limb development GO:0060173 166 0.122
renal tubule morphogenesis GO:0061333 72 0.120
Mouse
leukocyte differentiation GO:0002521 342 0.119
apoptotic signaling pathway GO:0097190 306 0.119
endocrine pancreas development GO:0031018 29 0.118
Mouse
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.118
Mouse
endocardial cushion to mesenchymal transition involved in heart valve formation GO:0003199 4 0.117
rhythmic process GO:0048511 174 0.115
Mouse
camera type eye development GO:0043010 266 0.115
Mouse
cell maturation GO:0048469 127 0.114
Mouse
epithelial tube formation GO:0072175 130 0.113
Mouse
embryonic epithelial tube formation GO:0001838 130 0.112
Mouse
multicellular organismal homeostasis GO:0048871 164 0.112
purine ribonucleotide biosynthetic process GO:0009152 59 0.110
negative regulation of cellular amine metabolic process GO:0033239 1 0.107
embryonic placenta development GO:0001892 98 0.106
Mouse
negative regulation of phosphorus metabolic process GO:0010563 184 0.106
homeostasis of number of cells GO:0048872 210 0.105
myeloid leukocyte differentiation GO:0002573 119 0.105
auditory receptor cell fate specification GO:0042667 1 0.105
regulation of neural retina development GO:0061074 3 0.103
epithelial cell development GO:0002064 159 0.103
positive regulation of auditory receptor cell differentiation GO:0045609 1 0.102
astrocyte fate commitment GO:0060018 4 0.101
negative regulation of cellular protein metabolic process GO:0032269 247 0.100
negative regulation of protein metabolic process GO:0051248 282 0.100
organonitrogen compound biosynthetic process GO:1901566 192 0.100
regulation of secretion GO:0051046 274 0.096
astrocyte differentiation GO:0048708 43 0.095
Mouse
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.095
regulation of retina development in camera type eye GO:1902866 3 0.095
regulation of protein localization GO:0032880 231 0.095
forebrain neuron differentiation GO:0021879 52 0.095
monosaccharide metabolic process GO:0005996 106 0.094
positive regulation of cellular amine metabolic process GO:0033240 5 0.094
organic hydroxy compound biosynthetic process GO:1901617 77 0.094
carbohydrate metabolic process GO:0005975 230 0.092
fear response GO:0042596 33 0.092
glandular epithelial cell differentiation GO:0002067 38 0.090
Mouse
blood circulation GO:0008015 195 0.088
spermatogenesis GO:0007283 284 0.088
atrial cardiac muscle cell differentiation GO:0055011 2 0.088
regulation of cell growth GO:0001558 91 0.087
cellular component assembly involved in morphogenesis GO:0010927 139 0.086
regulation of mast cell differentiation GO:0060375 3 0.086
regulation of mitotic cell cycle GO:0007346 126 0.085
Mouse
positive regulation of stem cell differentiation GO:2000738 23 0.084
regulation of cell cycle GO:0051726 281 0.084
Mouse
carbohydrate homeostasis GO:0033500 128 0.083
forebrain neuron development GO:0021884 30 0.083
cation transport GO:0006812 399 0.082
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.082
divalent inorganic cation transport GO:0072511 178 0.082
organelle assembly GO:0070925 177 0.081
gliogenesis GO:0042063 141 0.080
Mouse
negative regulation of myeloid cell differentiation GO:0045638 38 0.080
transdifferentiation GO:0060290 1 0.080
nucleobase containing small molecule metabolic process GO:0055086 352 0.079
ribonucleotide biosynthetic process GO:0009260 59 0.079
negative regulation of peroxisome proliferator activated receptor signaling pathway GO:0035359 3 0.079
negative regulation of neuron apoptotic process GO:0043524 92 0.078
sensory perception GO:0007600 245 0.077
protein ubiquitination GO:0016567 171 0.077
regulation of circadian rhythm GO:0042752 58 0.077
germ cell development GO:0007281 185 0.076
midbrain development GO:0030901 35 0.076
Mouse
purine ribonucleotide metabolic process GO:0009150 290 0.075
atrial cardiac muscle cell development GO:0055014 2 0.075
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.075
regulation of myeloid leukocyte differentiation GO:0002761 58 0.074
epithelial tube morphogenesis GO:0060562 303 0.074
Mouse
cell proliferation involved in heart valve development GO:2000793 2 0.073
regulation of oxidative phosphorylation uncoupler activity GO:2000275 3 0.073
embryonic organ morphogenesis GO:0048562 276 0.073
Mouse
atrioventricular node cell development GO:0060928 2 0.072
regulation of organ morphogenesis GO:2000027 144 0.071
Mouse
ovulation cycle GO:0042698 59 0.071
aortic valve morphogenesis GO:0003180 4 0.071
positive regulation of mechanoreceptor differentiation GO:0045633 1 0.071
semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:0071527 1 0.071
purine nucleotide metabolic process GO:0006163 302 0.070
male gamete generation GO:0048232 285 0.070
fat cell differentiation GO:0045444 160 0.070
Mouse
nucleoside phosphate metabolic process GO:0006753 338 0.070
multicellular organismal response to stress GO:0033555 62 0.070
appendage development GO:0048736 166 0.069
cellular lipid metabolic process GO:0044255 323 0.068
regulation of synaptic plasticity GO:0048167 87 0.068
positive regulation of semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:2000764 1 0.068
atrioventricular node cell differentiation GO:0060922 2 0.068
negative regulation of cardiac muscle cell apoptotic process GO:0010667 6 0.067
negative regulation of molecular function GO:0044092 258 0.067
labyrinthine layer development GO:0060711 49 0.066
Mouse
negative regulation of neuron death GO:1901215 98 0.066
divalent metal ion transport GO:0070838 172 0.066
hypophysis morphogenesis GO:0048850 3 0.065
mitral valve development GO:0003174 4 0.065
regulation of organelle organization GO:0033043 289 0.065
blood vessel morphogenesis GO:0048514 285 0.065
Mouse
axonogenesis GO:0007409 274 0.065
ear development GO:0043583 200 0.065
Mouse
development of primary sexual characteristics GO:0045137 143 0.065
somatotropin secreting cell differentiation GO:0060126 4 0.064
ventral spinal cord interneuron fate determination GO:0060580 1 0.064
stem cell development GO:0048864 219 0.064
Mouse
mitotic cell cycle GO:0000278 195 0.064
Mouse
forebrain generation of neurons GO:0021872 63 0.064
positive regulation of inner ear receptor cell differentiation GO:2000982 1 0.063
hippocampus development GO:0021766 52 0.063
negative regulation of phosphate metabolic process GO:0045936 184 0.062
forebrain development GO:0030900 302 0.062
Mouse
positive regulation of secretion by cell GO:1903532 114 0.062
nephron epithelium morphogenesis GO:0072088 68 0.062
Mouse
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.062
glucose metabolic process GO:0006006 92 0.062
response to extracellular stimulus GO:0009991 127 0.061
organic hydroxy compound metabolic process GO:1901615 203 0.060
mesenchymal cell development GO:0014031 93 0.060
Mouse
response to inorganic substance GO:0010035 96 0.060
proepicardium development GO:0003342 2 0.060
nucleotide biosynthetic process GO:0009165 78 0.060
ribose phosphate metabolic process GO:0019693 291 0.059
cardiac pacemaker cell fate commitment GO:0060927 1 0.059
regulation of wnt signaling pathway GO:0030111 123 0.059
sensory perception of pain GO:0019233 47 0.058
lens development in camera type eye GO:0002088 62 0.057
stem cell differentiation GO:0048863 268 0.057
Mouse
protein localization to organelle GO:0033365 185 0.056
Mouse
bone development GO:0060348 120 0.056
morphogenesis of a branching structure GO:0001763 203 0.056
pancreas development GO:0031016 57 0.056
Mouse
negative regulation of cellular component organization GO:0051129 194 0.056
negative regulation of synapse maturation GO:2000297 2 0.055
digestive tract morphogenesis GO:0048546 147 0.054
ventral spinal cord interneuron fate commitment GO:0060579 14 0.054
hexose metabolic process GO:0019318 98 0.054
regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000800 1 0.054
neuroblast differentiation GO:0014016 2 0.054
nephron epithelium development GO:0072009 92 0.054
Mouse
axon guidance GO:0007411 141 0.054
myeloid cell homeostasis GO:0002262 114 0.054
sclerotome development GO:0061056 4 0.053
cellular response to inorganic substance GO:0071241 37 0.053
bmp signaling pathway GO:0030509 93 0.053
Mouse
embryonic heart tube formation GO:0003144 1 0.052
negative regulation of type b pancreatic cell apoptotic process GO:2000675 3 0.052
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 24 0.052
protein modification by small protein conjugation or removal GO:0070647 207 0.052
positive regulation of synaptic plasticity GO:0031915 4 0.052
mitochondrion organization GO:0007005 134 0.052
nucleotide metabolic process GO:0009117 332 0.052
neuromuscular process GO:0050905 99 0.052
Fly
regulation of stem cell differentiation GO:2000736 50 0.052
negative regulation of protein modification process GO:0031400 163 0.052
ureteric bud morphogenesis GO:0060675 62 0.051
Mouse
regulation of homeostatic process GO:0032844 182 0.051
tendon formation GO:0035992 4 0.051
neuron projection guidance GO:0097485 141 0.051
response to organic cyclic compound GO:0014070 198 0.051
atrioventricular node cell fate commitment GO:0060929 1 0.050
non canonical wnt signaling pathway via mapk cascade GO:0038030 3 0.050
ossification GO:0001503 216 0.050
trophoblast giant cell differentiation GO:0060707 15 0.050
circulatory system process GO:0003013 197 0.050
spinal cord patterning GO:0021511 25 0.049
neural tube formation GO:0001841 108 0.049
circadian rhythm GO:0007623 114 0.049
negative regulation of oxidative phosphorylation uncoupler activity GO:2000276 2 0.049
septum transversum development GO:0003343 2 0.048
glucose homeostasis GO:0042593 128 0.048
cardiac muscle cell differentiation GO:0055007 69 0.048
negative regulation of phosphorylation GO:0042326 166 0.048
lymphocyte differentiation GO:0030098 242 0.048
cyclic nucleotide biosynthetic process GO:0009190 44 0.047
regulation of purine nucleotide metabolic process GO:1900542 169 0.047
positive regulation of programmed cell death GO:0043068 218 0.047
organophosphate biosynthetic process GO:0090407 122 0.047
regulation of cell cycle process GO:0010564 160 0.047
visceral serous pericardium development GO:0061032 2 0.047
locomotory behavior GO:0007626 195 0.046
Fly
regulation of peptide secretion GO:0002791 77 0.046
skeletal muscle cell differentiation GO:0035914 66 0.046
purkinje myocyte differentiation GO:0003168 1 0.046
steroid metabolic process GO:0008202 119 0.046
morphogenesis of a branching epithelium GO:0061138 193 0.046
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.046
Mouse
generation of precursor metabolites and energy GO:0006091 103 0.046
positive regulation of transferase activity GO:0051347 167 0.045
cardiac muscle cell apoptotic process GO:0010659 10 0.045
ear morphogenesis GO:0042471 118 0.045
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.045
regulation of hormone secretion GO:0046883 88 0.045
positive regulation of cardioblast differentiation GO:0051891 3 0.045
mesoderm formation GO:0001707 62 0.044
mesonephric duct formation GO:0072181 2 0.044
deltoid tuberosity development GO:0035993 3 0.044
carbohydrate derivative biosynthetic process GO:1901137 183 0.044
type b pancreatic cell differentiation GO:0003309 13 0.044
striated muscle cell development GO:0055002 125 0.044
adult behavior GO:0030534 135 0.044
cell fate determination involved in pattern specification GO:0060582 1 0.044
Fly
male sex differentiation GO:0046661 109 0.044
Worm
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.044
regulation of extent of cell growth GO:0061387 52 0.044
cellular response to metal ion GO:0071248 31 0.044
organelle localization GO:0051640 179 0.044
development of primary male sexual characteristics GO:0046546 88 0.043
regulation of map kinase activity GO:0043405 120 0.043
diencephalon development GO:0021536 63 0.043
Mouse
his purkinje system development GO:0003164 4 0.043
nephron tubule morphogenesis GO:0072078 68 0.043
Mouse
cognition GO:0050890 149 0.043
telencephalon development GO:0021537 186 0.043
Mouse
regulation of epidermis development GO:0045682 33 0.042
Mouse
male gonad development GO:0008584 88 0.042
establishment or maintenance of cell polarity GO:0007163 86 0.042
chondrocyte differentiation GO:0002062 72 0.042
cellular response to calcium ion GO:0071277 14 0.042
purine containing compound metabolic process GO:0072521 311 0.042
regulation of establishment of protein localization GO:0070201 181 0.042
limbic system development GO:0021761 72 0.042
synaptic transmission GO:0007268 329 0.042
regulation of sodium ion transport GO:0002028 29 0.041
somite development GO:0061053 81 0.041
Mouse
response to metal ion GO:0010038 47 0.041
regulation of striated muscle cell apoptotic process GO:0010662 11 0.041
camp biosynthetic process GO:0006171 31 0.041
regulation of heart contraction GO:0008016 77 0.041
development of primary female sexual characteristics GO:0046545 73 0.041
anatomical structure homeostasis GO:0060249 145 0.040
renal system development GO:0072001 225 0.040
Mouse
positive regulation of nervous system development GO:0051962 221 0.040
Mouse Fly
nucleoside phosphate biosynthetic process GO:1901293 79 0.040
regulation of carbohydrate metabolic process GO:0006109 75 0.040
spinal cord dorsal ventral patterning GO:0021513 23 0.040
regulation of kinase activity GO:0043549 249 0.040
regulation of intestinal epithelial structure maintenance GO:0060730 1 0.040
neural tube development GO:0021915 160 0.040
Mouse
positive regulation of secretion GO:0051047 130 0.040
mitotic cell cycle process GO:1903047 159 0.040
multicellular organismal metabolic process GO:0044236 28 0.040
negative regulation of growth GO:0045926 99 0.039
regulation of system process GO:0044057 200 0.039
behavioral defense response GO:0002209 28 0.039
regulation of nucleotide metabolic process GO:0006140 169 0.039
cartilage development GO:0051216 140 0.039
Mouse
mapk cascade GO:0000165 281 0.039
intracellular distribution of mitochondria GO:0048312 1 0.038
hindbrain development GO:0030902 128 0.038
Mouse
learning or memory GO:0007611 148 0.038
multicellular organism growth GO:0035264 161 0.038
regulation of glial cell differentiation GO:0045685 41 0.038
Mouse
primary neural tube formation GO:0014020 95 0.038
regulation of fat cell differentiation GO:0045598 81 0.038
Mouse
purine containing compound biosynthetic process GO:0072522 70 0.038
ribonucleotide metabolic process GO:0009259 291 0.038
paraxial mesodermal cell differentiation GO:0048342 2 0.037
ribose phosphate biosynthetic process GO:0046390 59 0.037
enteroendocrine cell differentiation GO:0035883 16 0.037
Mouse
cerebral cortex cell migration GO:0021795 44 0.037
segmentation GO:0035282 93 0.037
Mouse
placenta blood vessel development GO:0060674 31 0.037
Mouse
heart induction GO:0003129 2 0.037
actin cytoskeleton organization GO:0030036 220 0.037
regulation of epithelial to mesenchymal transition GO:0010717 22 0.037
glycerolipid metabolic process GO:0046486 122 0.036
central nervous system vasculogenesis GO:0022009 3 0.036
regulation of cartilage development GO:0061035 44 0.036
ameboidal type cell migration GO:0001667 128 0.036
cerebral cortex development GO:0021987 86 0.036
pulmonary myocardium development GO:0003350 3 0.036
regulation of membrane potential GO:0042391 192 0.036
Mouse
oxidation reduction process GO:0055114 342 0.036
nephron morphogenesis GO:0072028 69 0.036
Mouse
metanephros development GO:0001656 79 0.036
Mouse
embryonic skeletal system morphogenesis GO:0048704 91 0.036
venous blood vessel development GO:0060841 13 0.035
epithelial cell morphogenesis GO:0003382 41 0.035
tissue homeostasis GO:0001894 115 0.035
sensory system development GO:0048880 3 0.035
cytokine production GO:0001816 319 0.035
regulation of cyclic nucleotide metabolic process GO:0030799 40 0.034
respiratory system development GO:0060541 190 0.034
Mouse
tendon cell differentiation GO:0035990 4 0.034
cardiac muscle cell development GO:0055013 39 0.034
regulation of transferase activity GO:0051338 263 0.034
central nervous system neuron development GO:0021954 67 0.034
oligodendrocyte cell fate commitment GO:0021779 5 0.034
endomembrane system organization GO:0010256 147 0.033
neuron fate determination GO:0048664 9 0.033
Mouse
morphogenesis of embryonic epithelium GO:0016331 159 0.033
Mouse
plasma cell differentiation GO:0002317 3 0.033
female sex differentiation GO:0046660 84 0.033
lipid biosynthetic process GO:0008610 179 0.033
organelle fission GO:0048285 170 0.033
regulation of cardiac muscle cell apoptotic process GO:0010665 9 0.033
organic hydroxy compound transport GO:0015850 93 0.033
maintenance of location GO:0051235 89 0.033
cerebellar cortex development GO:0021695 48 0.033
formation of primary germ layer GO:0001704 77 0.033
catecholamine metabolic process GO:0006584 30 0.033
negative regulation of nervous system development GO:0051961 156 0.032
Mouse
hair follicle development GO:0001942 85 0.032
carboxylic acid transport GO:0046942 100 0.032
platelet morphogenesis GO:0036344 13 0.032
brown fat cell differentiation GO:0050873 36 0.032
skeletal muscle organ development GO:0060538 163 0.032
mechanoreceptor differentiation GO:0042490 67 0.032
Mouse
gonad development GO:0008406 141 0.032
regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation GO:2000079 1 0.032
regulation of inward rectifier potassium channel activity GO:1901979 1 0.032
response to drug GO:0042493 75 0.031
regulation of muscle tissue development GO:1901861 97 0.031
positive regulation of nucleotide biosynthetic process GO:0030810 26 0.031
epithelial cell fate commitment GO:0072148 13 0.031
Mouse
transmembrane transport GO:0055085 412 0.031
definitive hemopoiesis GO:0060216 20 0.031
regulation of apoptotic signaling pathway GO:2001233 197 0.031
inner ear morphogenesis GO:0042472 101 0.031
regulation of voltage gated calcium channel activity GO:1901385 4 0.031
negative regulation of cell cycle GO:0045786 123 0.031
establishment of protein localization to membrane GO:0090150 54 0.031
heart field specification GO:0003128 6 0.031
canonical wnt signaling pathway GO:0060070 130 0.031
b cell activation GO:0042113 161 0.031
phenol containing compound metabolic process GO:0018958 60 0.031
hair cycle GO:0042633 90 0.031
protein modification by small protein conjugation GO:0032446 187 0.031
nephron tubule development GO:0072080 84 0.031
Mouse
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development GO:0060528 4 0.031
striated muscle cell apoptotic process GO:0010658 12 0.031
cell differentiation involved in embryonic placenta development GO:0060706 26 0.030
trunk segmentation GO:0035290 4 0.030
limb morphogenesis GO:0035108 149 0.030
type b pancreatic cell fate commitment GO:0003327 1 0.030
regulation of cell migration GO:0030334 219 0.030
cd4 positive alpha beta t cell activation GO:0035710 45 0.030
adult locomotory behavior GO:0008344 91 0.030
hormone secretion GO:0046879 128 0.030
spinal cord development GO:0021510 81 0.030
negative regulation of organelle organization GO:0010639 90 0.030
cellular response to external stimulus GO:0071496 88 0.030
lateral inhibition GO:0046331 1 0.030
Mouse
amide transport GO:0042886 138 0.030
clara cell differentiation GO:0060486 4 0.030
cyclic nucleotide metabolic process GO:0009187 59 0.030
cardiac muscle cell proliferation GO:0060038 31 0.030
nerve development GO:0021675 67 0.030
Mouse
ganglion development GO:0061548 13 0.030
cardiac cell development GO:0055006 41 0.030
cerebral cortex neuron differentiation GO:0021895 19 0.029
regulation of muscle cell apoptotic process GO:0010660 17 0.029
compound eye development GO:0048749 1 0.029
Fly
learning GO:0007612 98 0.029
positive regulation of apoptotic process GO:0043065 217 0.029
positive regulation of growth hormone secretion GO:0060124 3 0.029
calcium ion transport GO:0006816 159 0.029
negative regulation of interleukin 13 secretion GO:2000666 1 0.029
regulation of cyclic nucleotide biosynthetic process GO:0030802 31 0.029
placenta development GO:0001890 140 0.029
Mouse
midbrain hindbrain boundary maturation GO:0021732 1 0.029
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.029
divalent inorganic cation homeostasis GO:0072507 138 0.028
regulation of ion transport GO:0043269 215 0.028
cell substrate adhesion GO:0031589 130 0.028
cell cell junction organization GO:0045216 72 0.028
gastrulation GO:0007369 116 0.028
negative regulation of apoptotic signaling pathway GO:2001234 104 0.028
muscle cell apoptotic process GO:0010657 18 0.028
auditory receptor cell fate determination GO:0042668 3 0.028
Mouse
regulation of calcium mediated signaling GO:0050848 19 0.028
glial cell fate commitment GO:0021781 14 0.028
Mouse
acylglycerol metabolic process GO:0006639 55 0.028
regulation of auditory receptor cell differentiation GO:0045607 4 0.028
Mouse
paraxial mesodermal cell fate commitment GO:0048343 2 0.028
protein localization to membrane GO:0072657 108 0.028
telencephalon cell migration GO:0022029 55 0.028
positive regulation of renal sodium excretion GO:0035815 2 0.028
heart process GO:0003015 94 0.028
regulation of leukocyte differentiation GO:1902105 159 0.028
associative learning GO:0008306 61 0.028
striated muscle cell proliferation GO:0014855 39 0.028
bronchiole development GO:0060435 3 0.028
monocarboxylic acid transport GO:0015718 44 0.028
response to oxygen levels GO:0070482 62 0.027
triglyceride metabolic process GO:0006641 51 0.027
posttranscriptional regulation of gene expression GO:0010608 155 0.027
cell fate specification GO:0001708 72 0.027
Worm
regulation of exit from mitosis GO:0007096 1 0.027
positive regulation of protein modification process GO:0031401 299 0.027
Mouse
cellular carbohydrate metabolic process GO:0044262 119 0.027
renal tubule development GO:0061326 87 0.027
Mouse
nuclear division GO:0000280 158 0.027
non canonical wnt signaling pathway via jnk cascade GO:0038031 3 0.027
epithelial cell maturation GO:0002070 15 0.027
regulation of epithelial cell proliferation GO:0050678 141 0.027
branching involved in ureteric bud morphogenesis GO:0001658 56 0.027
mesoderm morphogenesis GO:0048332 64 0.026
small molecule biosynthetic process GO:0044283 132 0.026
mesonephric duct morphogenesis GO:0072180 4 0.026
pallium development GO:0021543 120 0.026
peptidyl tyrosine modification GO:0018212 145 0.026
Mouse
female gonad development GO:0008585 71 0.026
immune effector process GO:0002252 321 0.026
hydrogen transport GO:0006818 35 0.026
positive regulation of exit from mitosis GO:0031536 1 0.026
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.026
response to calcium ion GO:0051592 20 0.026
cellular response to dna damage stimulus GO:0006974 207 0.026
Fly
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.026
cellular response to organonitrogen compound GO:0071417 145 0.026
heart growth GO:0060419 45 0.026
regulation of body fluid levels GO:0050878 162 0.026
sensory organ morphogenesis GO:0090596 242 0.026
Fly
dendrite development GO:0016358 115 0.026
Fly
regulation of glucose metabolic process GO:0010906 60 0.026
respiratory gaseous exchange GO:0007585 43 0.026
regulation of generation of precursor metabolites and energy GO:0043467 38 0.025
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.025
Mouse
cellular metal ion homeostasis GO:0006875 151 0.025
regulation of g protein activated inward rectifier potassium channel activity GO:1900128 1 0.025
positive regulation of semaphorin plexin signaling pathway GO:2001262 1 0.025
regulation of protein maturation GO:1903317 96 0.025
exocrine system development GO:0035272 45 0.025
positive regulation of cell growth GO:0030307 33 0.025
response to transforming growth factor beta GO:0071559 88 0.025
tube formation GO:0035148 140 0.025
Mouse
gtp catabolic process GO:0006184 143 0.025
positive regulation of keratinocyte proliferation GO:0010838 4 0.025
neutral lipid metabolic process GO:0006638 57 0.025
positive regulation of voltage gated calcium channel activity GO:1901387 2 0.025
regulation of binding GO:0051098 111 0.025
Mouse
fatty acid metabolic process GO:0006631 121 0.025
regulation of nucleotide biosynthetic process GO:0030808 34 0.025
multicellular organismal macromolecule metabolic process GO:0044259 19 0.025
regulation of blood circulation GO:1903522 93 0.025
defense response to other organism GO:0098542 197 0.024

Hes2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.066
disease of anatomical entity DOID:7 0 0.066
nervous system disease DOID:863 0 0.066
disease of metabolism DOID:0014667 0 0.053