Mus musculus

316 known processes

Hes5

hairy and enhancer of split 5 (Drosophila)

(Aliases: bHLHb38)

Hes5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
auditory receptor cell fate determination GO:0042668 3 0.998
motor neuron migration GO:0097475 4 0.992
renal tubule development GO:0061326 87 0.987
diencephalon development GO:0021536 63 0.987
Mouse
negative regulation of pancreatic a cell differentiation GO:2000227 1 0.986
Mouse
forebrain development GO:0030900 302 0.985
regulation of auditory receptor cell differentiation GO:0045607 4 0.984
Mouse
midbrain hindbrain boundary morphogenesis GO:0021555 4 0.983
Mouse
s shaped body morphogenesis GO:0072050 6 0.976
embryonic epithelial tube formation GO:0001838 130 0.972
regulation of somitogenesis GO:0014807 6 0.970
Mouse
brain segmentation GO:0035284 3 0.969
lateral motor column neuron migration GO:0097477 3 0.968
regulation of gliogenesis GO:0014013 50 0.967
mesonephric epithelium development GO:0072163 94 0.966
Mouse
outflow tract morphogenesis GO:0003151 53 0.964
Mouse
kidney development GO:0001822 213 0.962
placenta blood vessel development GO:0060674 31 0.961
Mouse
ureteric bud development GO:0001657 94 0.959
Mouse
loop of henle development GO:0072070 10 0.958
spinal cord motor neuron migration GO:0097476 4 0.958
neuron fate specification GO:0048665 30 0.958
peripheral nervous system neuron axonogenesis GO:0048936 3 0.957
Zebrafish
regulation of mechanoreceptor differentiation GO:0045631 5 0.955
specification of loop of henle identity GO:0072086 4 0.951
telencephalon development GO:0021537 186 0.950
morphogenesis of embryonic epithelium GO:0016331 159 0.950
ureteric bud morphogenesis GO:0060675 62 0.944
Mouse
inner ear receptor cell differentiation GO:0060113 61 0.942
negative regulation of glial cell differentiation GO:0045686 21 0.938
olfactory bulb development GO:0021772 30 0.934
olfactory lobe development GO:0021988 32 0.934
cerebral cortex neuron differentiation GO:0021895 19 0.933
visceral motor neuron differentiation GO:0021524 3 0.930
hair cell differentiation GO:0035315 40 0.929
epidermis development GO:0008544 187 0.927
nephron epithelium morphogenesis GO:0072088 68 0.924
forebrain neuron fate commitment GO:0021877 13 0.923
embryonic organ morphogenesis GO:0048562 276 0.919
Mouse
kidney epithelium development GO:0072073 121 0.911
mesonephros development GO:0001823 97 0.909
Mouse
ventral spinal cord interneuron differentiation GO:0021514 16 0.905
mesonephric tubule development GO:0072164 94 0.905
Mouse
labyrinthine layer blood vessel development GO:0060716 21 0.900
Mouse
cell proliferation in forebrain GO:0021846 30 0.896
central nervous system segmentation GO:0035283 3 0.894
dentate gyrus development GO:0021542 14 0.891
auditory receptor cell differentiation GO:0042491 37 0.891
stem cell development GO:0048864 219 0.890
stem cell differentiation GO:0048863 268 0.890
granulocyte colony stimulating factor production GO:0071611 1 0.885
mesonephric tubule morphogenesis GO:0072171 63 0.884
Mouse
nephron epithelium development GO:0072009 92 0.880
positive regulation of nephron tubule epithelial cell differentiation GO:2000768 1 0.880
nephric duct elongation GO:0035849 1 0.876
mesenchyme development GO:0060485 152 0.876
Mouse
regionalization GO:0003002 337 0.875
forebrain generation of neurons GO:0021872 63 0.875
Rat
metanephric tubule development GO:0072170 18 0.874
negative regulation of mechanoreceptor differentiation GO:0045632 3 0.874
appendage morphogenesis GO:0035107 149 0.873
nephron tubule development GO:0072080 84 0.864
cerebral cortex gabaergic interneuron differentiation GO:0021892 9 0.852
ectoderm formation GO:0001705 3 0.851
glial cell fate commitment GO:0021781 14 0.849
central nervous system neuron development GO:0021954 67 0.846
regulation of neuron differentiation GO:0045664 281 0.840
positive regulation of macrophage colony stimulating factor production GO:1901258 1 0.838
epithelial tube formation GO:0072175 130 0.835
amine metabolic process GO:0009308 45 0.831
forebrain neuron differentiation GO:0021879 52 0.830
Rat
spinal cord development GO:0021510 81 0.826
pituitary gland development GO:0021983 38 0.825
Mouse
cell fate commitment GO:0045165 210 0.823
gland development GO:0048732 330 0.821
Mouse
cerebral cortex radially oriented cell migration GO:0021799 31 0.817
cerebral cortex development GO:0021987 86 0.813
aorta morphogenesis GO:0035909 22 0.808
Mouse
sensory organ morphogenesis GO:0090596 242 0.788
Fly
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.782
nephron morphogenesis GO:0072028 69 0.781
mesenchymal cell development GO:0014031 93 0.780
Mouse
cerebral cortex gabaergic interneuron migration GO:0021853 6 0.777
limbic system development GO:0021761 72 0.776
retinal ganglion cell axon guidance GO:0031290 18 0.774
metanephric dct cell differentiation GO:0072240 3 0.770
renal system development GO:0072001 225 0.765
regulation of epidermal cell differentiation GO:0045604 21 0.764
Mouse
negative regulation of glial cell proliferation GO:0060253 4 0.763
Mouse
embryonic placenta development GO:0001892 98 0.762
Mouse
neural tube closure GO:0001843 90 0.762
forebrain regionalization GO:0021871 25 0.757
hippocampus development GO:0021766 52 0.756
ear morphogenesis GO:0042471 118 0.752
metanephros development GO:0001656 79 0.750
cardiac cell fate determination GO:0060913 2 0.749
pallium development GO:0021543 120 0.748
substrate independent telencephalic tangential migration GO:0021826 8 0.744
neural crest cell development GO:0014032 48 0.744
Mouse
metanephric nephron tubule development GO:0072234 16 0.736
central nervous system neuron differentiation GO:0021953 162 0.735
Rat
cell differentiation involved in kidney development GO:0061005 33 0.731
Mouse
cardiac chamber morphogenesis GO:0003206 93 0.729
Mouse
cell differentiation in spinal cord GO:0021515 53 0.722
nephron tubule formation GO:0072079 20 0.721
forebrain neuron development GO:0021884 30 0.720
spinal cord motor neuron cell fate specification GO:0021520 13 0.719
inner cell mass cell differentiation GO:0001826 7 0.718
hindbrain morphogenesis GO:0021575 46 0.715
Mouse
nephron tubule morphogenesis GO:0072078 68 0.712
somatotropin secreting cell differentiation GO:0060126 4 0.705
trabecular meshwork development GO:0002930 2 0.704
renal vesicle development GO:0072087 17 0.702
epithalamus development GO:0021538 2 0.702
cell fate specification GO:0001708 72 0.701
Worm
positive regulation of epithelial cell differentiation involved in kidney development GO:2000698 2 0.700
regulation of neuron projection development GO:0010975 169 0.692
nephron development GO:0072006 109 0.682
placenta development GO:0001890 140 0.674
Mouse
substrate independent telencephalic tangential interneuron migration GO:0021843 8 0.673
heart morphogenesis GO:0003007 178 0.673
Mouse
cranial nerve development GO:0021545 41 0.670
Mouse
regulation of inner ear receptor cell differentiation GO:2000980 5 0.670
spinal cord motor neuron differentiation GO:0021522 35 0.669
tube closure GO:0060606 91 0.668
retinal bipolar neuron differentiation GO:0060040 5 0.665
hypothalamus development GO:0021854 16 0.665
negative regulation of stomach neuroendocrine cell differentiation GO:0061106 1 0.662
Mouse
bmp signaling pathway GO:0030509 93 0.655
somitogenesis GO:0001756 69 0.651
Zebrafish Mouse
peripheral nervous system neuron development GO:0048935 9 0.649
Zebrafish
compound eye development GO:0048749 1 0.648
Fly
muscle cell differentiation GO:0042692 261 0.646
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.638
adenohypophysis development GO:0021984 14 0.631
Mouse
regulation of binding GO:0051098 111 0.617
Mouse
somatic stem cell maintenance GO:0035019 47 0.617
Mouse
metanephros morphogenesis GO:0003338 24 0.616
ventral spinal cord interneuron fate commitment GO:0060579 14 0.615
gliogenesis GO:0042063 141 0.615
neuron apoptotic process GO:0051402 142 0.614
stomach neuroendocrine cell differentiation GO:0061102 2 0.612
Mouse
segmentation GO:0035282 93 0.610
neurohypophysis development GO:0021985 2 0.609
positive regulation of glial cell differentiation GO:0045687 21 0.608
Mouse
axonogenesis GO:0007409 274 0.602
Zebrafish
renal vesicle induction GO:0072034 3 0.599
cell maturation GO:0048469 127 0.599
ventral spinal cord interneuron specification GO:0021521 11 0.597
rostrocaudal neural tube patterning GO:0021903 12 0.597
Mouse
transdifferentiation GO:0060290 1 0.589
interneuron migration from the subpallium to the cortex GO:0021830 7 0.587
neural crest cell differentiation GO:0014033 54 0.584
Mouse
cerebellum development GO:0021549 77 0.584
oligodendrocyte differentiation GO:0048709 53 0.578
regulation of astrocyte differentiation GO:0048710 20 0.573
somatotropin secreting cell development GO:0060133 2 0.573
hindbrain development GO:0030902 128 0.572
Mouse
urogenital system development GO:0001655 261 0.571
action potential GO:0001508 78 0.568
negative regulation of neuron differentiation GO:0045665 101 0.567
regulation of epidermis development GO:0045682 33 0.566
Mouse
stem cell fate specification GO:0048866 3 0.566
positive regulation of branching involved in ureteric bud morphogenesis GO:0090190 18 0.565
artery development GO:0060840 53 0.560
Mouse
embryonic retina morphogenesis in camera type eye GO:0060059 7 0.559
cardiac septum development GO:0003279 59 0.556
Mouse
neuroblast differentiation GO:0014016 2 0.554
astrocyte fate commitment GO:0060018 4 0.550
appendage development GO:0048736 166 0.545
negative regulation of cell development GO:0010721 169 0.543
primary neural tube formation GO:0014020 95 0.540
cardiac ventricle morphogenesis GO:0003208 50 0.540
ear development GO:0043583 200 0.525
notch signaling pathway GO:0007219 71 0.523
regulation of neuron apoptotic process GO:0043523 122 0.521
positive regulation of cell development GO:0010720 237 0.520
Mouse Fly
carbon catabolite repression of transcription from rna polymerase ii promoter GO:0000437 1 0.520
cardioblast proliferation GO:0003263 8 0.518
Mouse
branching involved in ureteric bud morphogenesis GO:0001658 56 0.515
cerebral cortex gabaergic interneuron development GO:0021894 6 0.513
mesoderm development GO:0007498 100 0.508
Fly
paraxial mesodermal cell differentiation GO:0048342 2 0.508
neuromuscular process GO:0050905 99 0.507
Fly
epithelial to mesenchymal transition GO:0001837 47 0.505
cerebellar purkinje cell layer development GO:0021680 26 0.504
neural tube formation GO:0001841 108 0.502
comma shaped body morphogenesis GO:0072049 5 0.500
glial cell differentiation GO:0010001 131 0.499
anterior commissure morphogenesis GO:0021960 6 0.499
ascending aorta morphogenesis GO:0035910 3 0.495
Mouse
ventricular septum morphogenesis GO:0060412 27 0.488
Mouse
metanephric nephron development GO:0072210 34 0.481
olfactory bulb interneuron differentiation GO:0021889 12 0.478
cellular amine metabolic process GO:0044106 44 0.475
metencephalon development GO:0022037 89 0.472
telencephalon regionalization GO:0021978 14 0.470
gabaergic neuron differentiation GO:0097154 11 0.468
endocrine system development GO:0035270 98 0.467
Mouse
telencephalon cell migration GO:0022029 55 0.463
developmental growth involved in morphogenesis GO:0060560 138 0.461
t cell activation GO:0042110 289 0.458
Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.457
horizontal cell localization GO:0035852 1 0.456
trigeminal nerve development GO:0021559 10 0.455
specification of nephron tubule identity GO:0072081 5 0.450
forebrain cell migration GO:0021885 58 0.447
regulation of cellular amino acid metabolic process GO:0006521 5 0.446
cellular amino acid metabolic process GO:0006520 103 0.445
satellite cell activation involved in skeletal muscle regeneration GO:0014901 3 0.439
motor neuron axon guidance GO:0008045 26 0.439
negative regulation of molecular function GO:0044092 258 0.438
astrocyte differentiation GO:0048708 43 0.437
mesenchymal cell differentiation GO:0048762 107 0.435
Mouse
neuronal action potential GO:0019228 54 0.434
metanephric nephron morphogenesis GO:0072273 19 0.427
positive regulation of auditory receptor cell differentiation GO:0045609 1 0.426
cerebral cortex cell migration GO:0021795 44 0.425
kidney morphogenesis GO:0060993 83 0.420
neural tube development GO:0021915 160 0.417
medial motor column neuron differentiation GO:0021526 2 0.416
pancreas development GO:0031016 57 0.416
Mouse
cerebral cortex tangential migration GO:0021800 7 0.415
cardiac neural crest cell differentiation involved in heart development GO:0061307 8 0.415
Mouse
renal tubule morphogenesis GO:0061333 72 0.413
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.412
cervix development GO:0060067 2 0.410
cardiac muscle cell differentiation GO:0055007 69 0.409
negative regulation of cell proliferation GO:0008285 296 0.407
Mouse
anterior head development GO:0097065 2 0.407
pancreatic a cell differentiation GO:0003310 7 0.406
Mouse
cardiac neural crest cell migration involved in outflow tract morphogenesis GO:0003253 3 0.405
retina development in camera type eye GO:0060041 119 0.404
regulation of neural retina development GO:0061074 3 0.400
striated muscle tissue development GO:0014706 293 0.398
camera type eye development GO:0043010 266 0.389
heart valve morphogenesis GO:0003179 21 0.389
embryonic appendage morphogenesis GO:0035113 126 0.389
sensory perception GO:0007600 245 0.388
olfactory bulb interneuron development GO:0021891 7 0.387
negative regulation of nervous system development GO:0051961 156 0.383
lymphocyte differentiation GO:0030098 242 0.382
regulation of timing of neuron differentiation GO:0060164 5 0.380
Mouse
positive regulation of tyrosine phosphorylation of stat3 protein GO:0042517 7 0.376
aorta development GO:0035904 23 0.376
Mouse
pattern specification involved in metanephros development GO:0072268 4 0.374
regulation of secondary heart field cardioblast proliferation GO:0003266 9 0.373
Mouse
nose development GO:0043584 12 0.371
regulation of kidney development GO:0090183 40 0.369
cell proliferation in hindbrain GO:0021534 10 0.368
cerebellar granule cell precursor proliferation GO:0021930 10 0.368
ventricular septum development GO:0003281 42 0.368
Mouse
atrioventricular valve morphogenesis GO:0003181 13 0.366
skin development GO:0043588 220 0.366
trochlear nerve development GO:0021558 3 0.365
Mouse
cerebellar purkinje cell differentiation GO:0021702 13 0.360
positive regulation of mitotic cell cycle embryonic GO:0045977 2 0.358
Mouse
metanephric epithelium development GO:0072207 21 0.357
regulation of bmp signaling pathway GO:0030510 60 0.357
neuron fate determination GO:0048664 9 0.357
maintenance of epithelial cell apical basal polarity GO:0045199 2 0.355
cardiac chamber development GO:0003205 108 0.355
Mouse
regulation of mitotic cell cycle GO:0007346 126 0.355
Mouse
negative regulation of auditory receptor cell differentiation GO:0045608 2 0.354
Mouse
cell fate specification involved in pattern specification GO:0060573 11 0.354
mitral valve morphogenesis GO:0003183 4 0.352
nerve development GO:0021675 67 0.350
Mouse
endodermal cell fate commitment GO:0001711 12 0.348
muscle tissue morphogenesis GO:0060415 53 0.346
paraxial mesodermal cell fate commitment GO:0048343 2 0.345
positive regulation of cellular amine metabolic process GO:0033240 5 0.340
cardiac epithelial to mesenchymal transition GO:0060317 18 0.337
metanephric s shaped body morphogenesis GO:0072284 2 0.335
forebrain morphogenesis GO:0048853 17 0.332
endocardial cushion to mesenchymal transition involved in heart valve formation GO:0003199 4 0.324
positive regulation of anterior head development GO:2000744 2 0.322
cardiac ventricle development GO:0003231 83 0.319
Mouse
epithelial cell fate commitment GO:0072148 13 0.318
midbrain development GO:0030901 35 0.315
Mouse
establishment of protein localization to organelle GO:0072594 118 0.314
Mouse
regulation of macrophage colony stimulating factor production GO:1901256 1 0.314
limb morphogenesis GO:0035108 149 0.313
pharyngeal system development GO:0060037 17 0.310
Mouse
olfactory nerve development GO:0021553 3 0.308
metanephric nephron tubule morphogenesis GO:0072282 7 0.308
positive regulation of mesonephros development GO:0061213 20 0.307
positive regulation of extracellular matrix organization GO:1903055 4 0.307
cochlea development GO:0090102 35 0.307
Mouse
oculomotor nerve development GO:0021557 4 0.305
Mouse
ascending aorta development GO:0035905 3 0.305
Mouse
mechanoreceptor differentiation GO:0042490 67 0.304
positive regulation of secondary heart field cardioblast proliferation GO:0072513 4 0.304
peptidyl tyrosine modification GO:0018212 145 0.303
muscle cell development GO:0055001 133 0.303
Mouse
neuron projection guidance GO:0097485 141 0.302
renal vesicle morphogenesis GO:0072077 15 0.296
thick ascending limb development GO:0072023 2 0.294
regulation of satellite cell activation involved in skeletal muscle regeneration GO:0014717 3 0.292
positive regulation of inner ear receptor cell differentiation GO:2000982 1 0.292
ensheathment of neurons GO:0007272 76 0.292
metanephric loop of henle development GO:0072236 4 0.291
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.288
regulation of vasculature development GO:1901342 88 0.287
commitment of neuronal cell to specific neuron type in forebrain GO:0021902 7 0.287
oviduct epithelium development GO:0035846 1 0.285
macrophage colony stimulating factor production GO:0036301 1 0.285
regulation of granulocyte macrophage colony stimulating factor production GO:0032645 3 0.285
gonad morphogenesis GO:0035262 1 0.283
metanephric tubule morphogenesis GO:0072173 9 0.280
blood vessel morphogenesis GO:0048514 285 0.278
Mouse
tyrosine phosphorylation of stat3 protein GO:0042503 12 0.277
sensory organ boundary specification GO:0008052 1 0.276
Fly
neuron death GO:0070997 154 0.274
regulation of retina development in camera type eye GO:1902866 3 0.274
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process GO:2000763 1 0.273
sensory perception of sound GO:0007605 97 0.270
morphogenesis of a branching epithelium GO:0061138 193 0.270
peripheral nervous system development GO:0007422 53 0.270
Zebrafish
neuron projection extension GO:1990138 64 0.269
regulation of branching involved in ureteric bud morphogenesis GO:0090189 22 0.267
regulation of ossification GO:0030278 112 0.267
cell differentiation in hindbrain GO:0021533 24 0.266
digestive system development GO:0055123 200 0.266
Mouse
spinal cord association neuron differentiation GO:0021527 14 0.266
autonomic nervous system development GO:0048483 43 0.264
Mouse
myelination GO:0042552 74 0.261
pyramidal neuron migration GO:0021852 1 0.260
organ growth GO:0035265 117 0.260
proximal distal pattern formation involved in nephron development GO:0072047 5 0.260
smoothened signaling pathway GO:0007224 105 0.258
ventral spinal cord development GO:0021517 48 0.257
cochlea morphogenesis GO:0090103 22 0.257
inner cell mass cell fate commitment GO:0001827 2 0.255
tube formation GO:0035148 140 0.253
rhombomere morphogenesis GO:0021593 2 0.252
glomerulus development GO:0032835 40 0.249
Mouse
ventricular compact myocardium morphogenesis GO:0003223 2 0.245
respiratory system development GO:0060541 190 0.244
Mouse
regulation of oligodendrocyte differentiation GO:0048713 23 0.243
embryonic heart tube morphogenesis GO:0003143 51 0.240
Mouse
tyrosine phosphorylation of stat protein GO:0007260 23 0.240
establishment or maintenance of apical basal cell polarity GO:0035088 21 0.236
regulation of response to wounding GO:1903034 189 0.234
endocardial cushion morphogenesis GO:0003203 18 0.232
metanephric nephron tubule formation GO:0072289 4 0.230
regulation of anterior head development GO:2000742 2 0.229
cerebral cortex regionalization GO:0021796 8 0.228
post anal tail morphogenesis GO:0036342 23 0.226
Mouse
preganglionic parasympathetic nervous system development GO:0021783 17 0.225
Mouse
proprioception GO:0019230 4 0.225
endocardial cushion development GO:0003197 26 0.224
cardiac atrium morphogenesis GO:0003209 23 0.222
maintenance of apical basal cell polarity GO:0035090 3 0.222
auditory receptor cell fate specification GO:0042667 1 0.221
positive regulation of transcription from rna polymerase ii promoter by glucose GO:0000432 3 0.216
inner ear receptor cell fate commitment GO:0060120 6 0.216
small molecule biosynthetic process GO:0044283 132 0.216
neuron migration GO:0001764 122 0.215
dendrite development GO:0016358 115 0.214
Fly
palate development GO:0060021 76 0.212
brain morphogenesis GO:0048854 32 0.210
Fly
branching morphogenesis of an epithelial tube GO:0048754 159 0.209
positive regulation of mechanoreceptor differentiation GO:0045633 1 0.209
regulation of dna binding GO:0051101 39 0.208
Mouse
noradrenergic neuron differentiation GO:0003357 6 0.207
regulation of cysteine type endopeptidase activity GO:2000116 65 0.205
negative regulation of mesodermal cell fate specification GO:0042662 3 0.203
nucleocytoplasmic transport GO:0006913 139 0.203
Mouse
epithelial tube morphogenesis GO:0060562 303 0.203
hypothalamus cell differentiation GO:0021979 8 0.202
epithelial cell differentiation involved in kidney development GO:0035850 23 0.201
cell proliferation in external granule layer GO:0021924 10 0.201
locomotory behavior GO:0007626 195 0.200
Fly
regulation of glial cell differentiation GO:0045685 41 0.199
canonical wnt signaling pathway GO:0060070 130 0.199
macula densa development GO:0072024 1 0.198
cerebellar cortex formation GO:0021697 22 0.198
positive regulation of granulocyte macrophage colony stimulating factor production GO:0032725 3 0.197
neuroepithelial cell differentiation GO:0060563 37 0.196
Mouse
positive regulation of kidney development GO:0090184 28 0.195
granulocyte macrophage colony stimulating factor production GO:0032604 3 0.195
common bile duct development GO:0061009 6 0.193
Mouse
regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000800 1 0.192
cardiac septum morphogenesis GO:0060411 46 0.192
Mouse
primary prostatic bud elongation GO:0060516 2 0.192
chemotaxis GO:0006935 247 0.191
regulation of cellular ketone metabolic process GO:0010565 66 0.188
cell fate commitment involved in pattern specification GO:0060581 14 0.187
Fly
regulation of nephron tubule epithelial cell differentiation GO:0072182 9 0.187
positive regulation of lens epithelial cell proliferation GO:2001111 1 0.187
labyrinthine layer development GO:0060711 49 0.187
Mouse
negative regulation of binding GO:0051100 39 0.186
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.185
Mouse
negative regulation of photoreceptor cell differentiation GO:0046533 4 0.185
negative regulation of oligodendrocyte differentiation GO:0048715 11 0.185
cardiac muscle cell myoblast differentiation GO:0060379 8 0.184
cerebellar purkinje cell layer morphogenesis GO:0021692 14 0.182
endodermal cell fate determination GO:0007493 2 0.182
cardiac neural crest cell development involved in outflow tract morphogenesis GO:0061309 6 0.181
Mouse
blastocyst growth GO:0001832 23 0.181
pancreatic pp cell differentiation GO:0003312 2 0.179
axon guidance GO:0007411 141 0.178
sensory system development GO:0048880 3 0.174
cerebellum morphogenesis GO:0021587 42 0.172
inner cell mass cellular morphogenesis GO:0001828 1 0.171
thalamus development GO:0021794 11 0.170
rhombomere development GO:0021546 8 0.169
developmental maturation GO:0021700 193 0.167
keratinocyte differentiation GO:0030216 48 0.167
renal system pattern specification GO:0072048 9 0.166
ascending thin limb development GO:0072021 2 0.166
mrna transcription from rna polymerase ii promoter GO:0042789 4 0.166
pattern specification involved in kidney development GO:0061004 8 0.166
cardiac muscle tissue development GO:0048738 130 0.166
positive regulation of bmp signaling pathway GO:0030513 23 0.164
regulation of stem cell differentiation GO:2000736 50 0.164
Human
positive regulation of cell activation GO:0050867 158 0.163
Mouse
cardiac atrium development GO:0003230 24 0.163
skeletal muscle cell differentiation GO:0035914 66 0.161
connective tissue development GO:0061448 179 0.161
somatic motor neuron differentiation GO:0021523 6 0.160
inner ear morphogenesis GO:0042472 101 0.160
b cell differentiation GO:0030183 78 0.159
positive regulation of granulocyte colony stimulating factor production GO:0071657 1 0.159
neural crest cell migration GO:0001755 32 0.159
regulation of lens epithelial cell proliferation GO:2001109 1 0.159
somite specification GO:0001757 4 0.159
cell type specific apoptotic process GO:0097285 268 0.157
atrial septum development GO:0003283 12 0.157
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.157
transmission of nerve impulse GO:0019226 76 0.156
positive regulation of skeletal muscle tissue regeneration GO:0043415 4 0.156
granulosa cell differentiation GO:0060014 1 0.155
axonal fasciculation GO:0007413 15 0.155
regulation of establishment of planar polarity GO:0090175 28 0.154
forebrain anterior posterior pattern specification GO:0021797 5 0.154
limb development GO:0060173 166 0.154
ectodermal cell differentiation GO:0010668 3 0.154
cerebellar cortex development GO:0021695 48 0.153
positive regulation of rhodopsin gene expression GO:0045872 2 0.153
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.151
positive regulation of neuron differentiation GO:0045666 141 0.150
regulation of apoptotic process involved in outflow tract morphogenesis GO:1902256 2 0.149
endodermal cell fate specification GO:0001714 4 0.147
mesonephric duct morphogenesis GO:0072180 4 0.146
spinal cord dorsal ventral patterning GO:0021513 23 0.146
protein localization to organelle GO:0033365 185 0.145
Mouse
negative regulation of epidermis development GO:0045683 9 0.145
Mouse
regulation of epithelial cell differentiation involved in kidney development GO:2000696 10 0.145
posttranscriptional regulation of gene expression GO:0010608 155 0.143
renal system vasculature development GO:0061437 15 0.141
Mouse
mitral valve development GO:0003174 4 0.141
midbrain hindbrain boundary maturation during brain development GO:0022004 1 0.140
negative regulation of inner ear receptor cell differentiation GO:2000981 3 0.139
angiogenesis GO:0001525 201 0.139
sclerotome development GO:0061056 4 0.139
central nervous system projection neuron axonogenesis GO:0021952 21 0.138
oligodendrocyte cell fate commitment GO:0021779 5 0.136
cardiac neural crest cell development involved in heart development GO:0061308 7 0.135
Mouse
coronary vasculature morphogenesis GO:0060977 9 0.134
negative regulation of neuron apoptotic process GO:0043524 92 0.133
regulation of peptidase activity GO:0052547 96 0.133
positive regulation of ossification GO:0045778 47 0.131
negative regulation of transcription by glucose GO:0045014 1 0.131
glomerulus vasculature development GO:0072012 14 0.131
Mouse
habenula development GO:0021986 2 0.129
b cell activation GO:0042113 161 0.129
regulation of heart growth GO:0060420 31 0.129
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.129
negative regulation of dna binding GO:0043392 20 0.129
regulation of mesonephros development GO:0061217 24 0.128
nephric duct morphogenesis GO:0072178 7 0.128
cardiocyte differentiation GO:0035051 87 0.128
Mouse
endocardial cushion to mesenchymal transition GO:0090500 5 0.128
embryonic viscerocranium morphogenesis GO:0048703 8 0.125
cell differentiation involved in embryonic placenta development GO:0060706 26 0.125
type b pancreatic cell differentiation GO:0003309 13 0.125
neuron maturation GO:0042551 29 0.124
dopaminergic neuron differentiation GO:0071542 14 0.124
regulation of neuron death GO:1901214 134 0.123
enteroendocrine cell differentiation GO:0035883 16 0.123
Mouse
positive regulation of neural precursor cell proliferation GO:2000179 42 0.122
Fly
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.122
cellular ketone metabolic process GO:0042180 84 0.122
renal interstitial fibroblast development GO:0072141 5 0.121
Mouse
renal capsule specification GO:0072130 1 0.121
nuclear transport GO:0051169 139 0.121
Mouse
subpallium development GO:0021544 20 0.120
heart formation GO:0060914 16 0.119
Mouse
cardiac muscle tissue morphogenesis GO:0055008 44 0.119
erythrocyte differentiation GO:0030218 88 0.118
cell proliferation involved in heart morphogenesis GO:0061323 15 0.118
Mouse
segment specification GO:0007379 15 0.117
t cell proliferation GO:0042098 120 0.117
Mouse
innervation GO:0060384 22 0.116
positive regulation of cardiac muscle tissue development GO:0055025 19 0.115
epithelial cell development GO:0002064 159 0.114
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.114
pancreatic pp cell fate commitment GO:0003329 2 0.113
regulation of transcription from rna polymerase ii promoter involved in definitive endodermal cell fate specification GO:0060807 1 0.113

Hes5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org