Mus musculus

0 known processes

Hibadh

3-hydroxyisobutyrate dehydrogenase

(Aliases: AI265272,6430402H10Rik)

Hibadh biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
carboxylic acid catabolic process GO:0046395 51 0.516
cellular amino acid catabolic process GO:0009063 25 0.450
cellular amino acid metabolic process GO:0006520 103 0.419
monocarboxylic acid catabolic process GO:0072329 27 0.363
small molecule catabolic process GO:0044282 71 0.349
coenzyme metabolic process GO:0006732 52 0.313
oxidation reduction process GO:0055114 342 0.264
monocarboxylic acid metabolic process GO:0032787 191 0.222
amino acid betaine metabolic process GO:0006577 7 0.194
fatty acid oxidation GO:0019395 28 0.182
nucleobase containing small molecule metabolic process GO:0055086 352 0.172
cellular ketone metabolic process GO:0042180 84 0.166
coenzyme biosynthetic process GO:0009108 23 0.153
organic acid catabolic process GO:0016054 51 0.151
lipid oxidation GO:0034440 29 0.142
thioester metabolic process GO:0035383 19 0.117
nucleoside phosphate metabolic process GO:0006753 338 0.103
generation of precursor metabolites and energy GO:0006091 103 0.100
ribonucleoside metabolic process GO:0009119 245 0.091
sulfur compound metabolic process GO:0006790 100 0.085
fatty acid catabolic process GO:0009062 25 0.078
cellular modified amino acid metabolic process GO:0006575 63 0.076
organonitrogen compound catabolic process GO:1901565 264 0.074
ribonucleoside triphosphate metabolic process GO:0009199 220 0.065
response to organonitrogen compound GO:0010243 246 0.065
regulation of cellular ketone metabolic process GO:0010565 66 0.062
cellular lipid metabolic process GO:0044255 323 0.062
sulfur compound biosynthetic process GO:0044272 37 0.057
branched chain amino acid catabolic process GO:0009083 2 0.057
purine ribonucleoside metabolic process GO:0046128 241 0.056
glycosyl compound metabolic process GO:1901657 246 0.055
purine nucleoside metabolic process GO:0042278 241 0.054
cellular amine metabolic process GO:0044106 44 0.054
purine nucleoside monophosphate metabolic process GO:0009126 81 0.051
acetyl coa biosynthetic process GO:0006085 5 0.049
protein localization to organelle GO:0033365 185 0.048
purine ribonucleotide metabolic process GO:0009150 290 0.046
nucleotide metabolic process GO:0009117 332 0.045
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.044
nucleoside metabolic process GO:0009116 246 0.043
lipid catabolic process GO:0016042 69 0.042
organic acid biosynthetic process GO:0016053 86 0.042
amine metabolic process GO:0009308 45 0.042
ribose phosphate metabolic process GO:0019693 291 0.041
ribonucleotide catabolic process GO:0009261 208 0.040
alpha amino acid catabolic process GO:1901606 18 0.039
hepaticobiliary system development GO:0061008 67 0.037
pyruvate transport GO:0006848 2 0.037
small molecule biosynthetic process GO:0044283 132 0.037
organic cyclic compound catabolic process GO:1901361 295 0.036
carboxylic acid biosynthetic process GO:0046394 86 0.036
alpha amino acid metabolic process GO:1901605 59 0.036
fatty acid alpha oxidation GO:0001561 2 0.035
liver development GO:0001889 66 0.033
medium chain fatty acid metabolic process GO:0051791 1 0.033
regulation of cellular amino acid metabolic process GO:0006521 5 0.033
nucleoside triphosphate metabolic process GO:0009141 230 0.031
energy derivation by oxidation of organic compounds GO:0015980 77 0.031
cellular nitrogen compound catabolic process GO:0044270 280 0.030
fatty acid metabolic process GO:0006631 121 0.029
negative regulation of protein metabolic process GO:0051248 282 0.028
cellular lipid catabolic process GO:0044242 52 0.027
positive regulation of protein modification process GO:0031401 299 0.026
purine containing compound metabolic process GO:0072521 311 0.026
nucleoside monophosphate metabolic process GO:0009123 85 0.026
ribonucleotide metabolic process GO:0009259 291 0.026
negative regulation of cell proliferation GO:0008285 296 0.025
negative regulation of phosphate metabolic process GO:0045936 184 0.024
purine nucleotide metabolic process GO:0006163 302 0.024
cell type specific apoptotic process GO:0097285 268 0.024
negative regulation of phosphorylation GO:0042326 166 0.024
fatty acid beta oxidation GO:0006635 16 0.024
purine nucleoside triphosphate metabolic process GO:0009144 226 0.024
homeostasis of number of cells GO:0048872 210 0.024
positive regulation of protein phosphorylation GO:0001934 242 0.023
negative regulation of apoptotic signaling pathway GO:2001234 104 0.023
regulation of cellular amine metabolic process GO:0033238 20 0.023
organophosphate catabolic process GO:0046434 232 0.023
endocytosis GO:0006897 168 0.023
acyl coa metabolic process GO:0006637 19 0.023
carnitine metabolic process GO:0009437 7 0.023
heterocycle catabolic process GO:0046700 280 0.023
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.022
regulation of apoptotic signaling pathway GO:2001233 197 0.021
negative regulation of cellular protein metabolic process GO:0032269 247 0.021
lipid biosynthetic process GO:0008610 179 0.021
muscle cell differentiation GO:0042692 261 0.021
response to organic cyclic compound GO:0014070 198 0.021
intrinsic apoptotic signaling pathway GO:0097193 132 0.021
glutamine family amino acid biosynthetic process GO:0009084 2 0.021
acyl coa biosynthetic process GO:0071616 7 0.020
monocarboxylic acid biosynthetic process GO:0072330 61 0.020
peptidyl amino acid modification GO:0018193 336 0.020
lipid modification GO:0030258 65 0.020
purine containing compound catabolic process GO:0072523 213 0.020
purine nucleoside catabolic process GO:0006152 205 0.019
negative regulation of phosphorus metabolic process GO:0010563 184 0.019
male gamete generation GO:0048232 285 0.019
regulation of protein localization GO:0032880 231 0.019
establishment of protein localization to peroxisome GO:0072663 4 0.019
atp metabolic process GO:0046034 75 0.018
hormone metabolic process GO:0042445 86 0.018
negative regulation of intracellular signal transduction GO:1902532 167 0.018
regulation of cellular catabolic process GO:0031329 242 0.018
cellular response to organonitrogen compound GO:0071417 145 0.018
aromatic compound catabolic process GO:0019439 286 0.018
purine nucleoside triphosphate catabolic process GO:0009146 203 0.018
substantia nigra development GO:0021762 2 0.018
carbohydrate derivative catabolic process GO:1901136 231 0.018
negative regulation of cellular amine metabolic process GO:0033239 1 0.018
fat cell differentiation GO:0045444 160 0.018
very long chain fatty acid catabolic process GO:0042760 2 0.017
response to molecule of bacterial origin GO:0002237 143 0.017
regulation of organelle organization GO:0033043 289 0.017
covalent chromatin modification GO:0016569 163 0.017
organic hydroxy compound metabolic process GO:1901615 203 0.017
ribonucleoside monophosphate metabolic process GO:0009161 80 0.017
neuron apoptotic process GO:0051402 142 0.017
mapk cascade GO:0000165 281 0.016
apoptotic signaling pathway GO:0097190 306 0.016
striated muscle tissue development GO:0014706 293 0.016
organonitrogen compound biosynthetic process GO:1901566 192 0.016
pyruvate transmembrane transport GO:1901475 2 0.016
cellular macromolecule catabolic process GO:0044265 206 0.016
cellular response to hormone stimulus GO:0032870 150 0.016
purine ribonucleotide catabolic process GO:0009154 208 0.016
intracellular protein transport GO:0006886 204 0.016
microtubule based process GO:0007017 236 0.016
protein homooligomerization GO:0051260 43 0.016
purine nucleotide catabolic process GO:0006195 211 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.016
regulation of mapk cascade GO:0043408 248 0.015
response to steroid hormone GO:0048545 56 0.015
protein oligomerization GO:0051259 67 0.015
protein targeting GO:0006605 143 0.015
myeloid cell differentiation GO:0030099 233 0.015
cellular respiration GO:0045333 38 0.015
negative regulation of multi organism process GO:0043901 68 0.015
maintenance of location GO:0051235 89 0.015
positive regulation of cellular amine metabolic process GO:0033240 5 0.015
ossification GO:0001503 216 0.015
regulation of transferase activity GO:0051338 263 0.015
reactive oxygen species metabolic process GO:0072593 84 0.015
regulation of cell activation GO:0050865 289 0.015
response to peptide GO:1901652 136 0.015
cofactor metabolic process GO:0051186 80 0.015
epithelial cell development GO:0002064 159 0.015
regulation of mitochondrial fission GO:0090140 3 0.015
regulation of kinase activity GO:0043549 249 0.014
nucleotide catabolic process GO:0009166 217 0.014
purine ribonucleoside catabolic process GO:0046130 205 0.014
positive regulation of organelle organization GO:0010638 128 0.014
regulation of hormone levels GO:0010817 211 0.014
gland development GO:0048732 330 0.014
microtubule cytoskeleton organization GO:0000226 157 0.014
reactive nitrogen species metabolic process GO:2001057 0 0.014
establishment of protein localization to organelle GO:0072594 118 0.014
cardiac muscle tissue development GO:0048738 130 0.014
nonribosomal peptide biosynthetic process GO:0019184 5 0.014
tissue homeostasis GO:0001894 115 0.013
negative regulation of protein modification process GO:0031400 163 0.013
muscle tissue development GO:0060537 308 0.013
regulation of neuron death GO:1901214 134 0.013
protein processing GO:0016485 163 0.013
regulation of lymphocyte activation GO:0051249 240 0.013
spermatogenesis GO:0007283 284 0.013
ribonucleoside triphosphate catabolic process GO:0009203 199 0.013
glycerol ether metabolic process GO:0006662 2 0.013
nucleocytoplasmic transport GO:0006913 139 0.013
epithelial cell proliferation GO:0050673 174 0.013
leukocyte differentiation GO:0002521 342 0.013
response to lipopolysaccharide GO:0032496 128 0.013
neuron death GO:0070997 154 0.013
membrane organization GO:0061024 245 0.013
chromatin modification GO:0016568 187 0.012
carbohydrate metabolic process GO:0005975 230 0.012
sensory perception GO:0007600 245 0.012
regulation of membrane potential GO:0042391 192 0.012
defense response to other organism GO:0098542 197 0.012
t cell differentiation GO:0030217 174 0.012
nadh metabolic process GO:0006734 1 0.012
regulation of cellular response to stress GO:0080135 159 0.012
macromolecule catabolic process GO:0009057 281 0.012
protein import GO:0017038 101 0.012
thioester biosynthetic process GO:0035384 7 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.012
neural precursor cell proliferation GO:0061351 121 0.012
histone modification GO:0016570 159 0.012
lipid localization GO:0010876 126 0.012
regulation of cytokine production GO:0001817 266 0.012
regulation of peptide transport GO:0090087 91 0.012
renal system development GO:0072001 225 0.012
nuclear transport GO:0051169 139 0.012
gonad development GO:0008406 141 0.012
immune effector process GO:0002252 321 0.011
transmembrane transport GO:0055085 412 0.011
regulation of protein serine threonine kinase activity GO:0071900 157 0.011
aldehyde catabolic process GO:0046185 4 0.011
glycosyl compound catabolic process GO:1901658 206 0.011
negative regulation of kinase activity GO:0033673 81 0.011
action potential GO:0001508 78 0.011
negative regulation of cellular component organization GO:0051129 194 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.011
small gtpase mediated signal transduction GO:0007264 97 0.011
nucleoside phosphate catabolic process GO:1901292 222 0.011
regulation of protein transport GO:0051223 163 0.011
regulation of multi organism process GO:0043900 111 0.011
cytokine production GO:0001816 319 0.011
cellular response to lipid GO:0071396 145 0.011
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.011
oxidoreduction coenzyme metabolic process GO:0006733 16 0.011
response to oxidative stress GO:0006979 123 0.011
lymphocyte proliferation GO:0046651 164 0.011
skeletal system development GO:0001501 356 0.011
development of primary sexual characteristics GO:0045137 143 0.011
response to catecholamine GO:0071869 4 0.011
response to copper ion GO:0046688 3 0.011
cellular response to molecule of bacterial origin GO:0071219 83 0.010
cell maturation GO:0048469 127 0.010
anion transport GO:0006820 177 0.010
regulation of secretion by cell GO:1903530 249 0.010
cytoplasmic transport GO:0016482 234 0.010
protein maturation GO:0051604 176 0.010
ribonucleoside catabolic process GO:0042454 206 0.010
response to peptide hormone GO:0043434 127 0.010
skeletal system morphogenesis GO:0048705 203 0.010
response to acid chemical GO:0001101 111 0.010
regulation of fat cell differentiation GO:0045598 81 0.010

Hibadh disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
inherited metabolic disorder DOID:655 0 0.664
disease of metabolism DOID:0014667 0 0.664
amino acid metabolic disorder DOID:9252 0 0.543
organic acidemia DOID:0060159 0 0.056
disease of anatomical entity DOID:7 0 0.019
nervous system disease DOID:863 0 0.019
organ system cancer DOID:0050686 0 0.013
cancer DOID:162 0 0.013
gastrointestinal system cancer DOID:3119 0 0.013
disease of cellular proliferation DOID:14566 0 0.013