Mus musculus

12 known processes

Hist1h1b

histone cluster 1, H1b

(Aliases: H1s-3,H1B,H1f5,H1.5)

Hist1h1b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein dna complex disassembly GO:0032986 1 0.336
nucleosome disassembly GO:0006337 1 0.278
chromatin organization GO:0006325 206 0.238
Human
chromatin assembly GO:0031497 13 0.228
meiotic nuclear division GO:0007126 115 0.201
dna conformation change GO:0071103 37 0.175
protein dna complex subunit organization GO:0071824 28 0.166
dna metabolic process GO:0006259 303 0.161
meiotic cell cycle GO:0051321 122 0.112
regulation of cellular amino acid metabolic process GO:0006521 5 0.111
male gamete generation GO:0048232 285 0.111
dna packaging GO:0006323 30 0.102
chromatin assembly or disassembly GO:0006333 16 0.097
cellular ketone metabolic process GO:0042180 84 0.096
germ cell development GO:0007281 185 0.092
chromatin disassembly GO:0031498 1 0.090
cellular amine metabolic process GO:0044106 44 0.089
regulation of cellular ketone metabolic process GO:0010565 66 0.076
germline cell cycle switching mitotic to meiotic cell cycle GO:0051729 1 0.072
transmembrane transport GO:0055085 412 0.068
spermatogenesis GO:0007283 284 0.064
organelle fission GO:0048285 170 0.061
intrinsic apoptotic signaling pathway GO:0097193 132 0.060
nuclear division GO:0000280 158 0.059
protein maturation GO:0051604 176 0.059
amine metabolic process GO:0009308 45 0.057
chromosome segregation GO:0007059 48 0.056
dna repair GO:0006281 107 0.055
apoptotic signaling pathway GO:0097190 306 0.054
fertilization GO:0009566 127 0.053
protein processing GO:0016485 163 0.052
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.051
ion transmembrane transport GO:0034220 361 0.050
negative regulation of cellular protein metabolic process GO:0032269 247 0.048
activation of meiosis GO:0090427 4 0.048
defense response to other organism GO:0098542 197 0.046
positive regulation of apoptotic signaling pathway GO:2001235 95 0.046
meiotic cell cycle process GO:1903046 77 0.045
cell cycle switching GO:0060184 1 0.045
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 35 0.045
regulation of meiotic cell cycle GO:0051445 34 0.044
regulation of cellular amine metabolic process GO:0033238 20 0.044
cellular amino acid metabolic process GO:0006520 103 0.044
chromatin modification GO:0016568 187 0.043
Human
cell cycle switching mitotic to meiotic cell cycle GO:0051728 1 0.041
nucleosome positioning GO:0016584 4 0.041
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.038
spermatid differentiation GO:0048515 115 0.038
negative regulation of protein metabolic process GO:0051248 282 0.038
single fertilization GO:0007338 82 0.037
regulation of transferase activity GO:0051338 263 0.034
leukocyte migration GO:0050900 124 0.034
regulation of cytokine production GO:0001817 266 0.034
cytokine production GO:0001816 319 0.034
cellular response to dna damage stimulus GO:0006974 207 0.034
response to organonitrogen compound GO:0010243 246 0.033
regulation of defense response GO:0031347 233 0.033
reactive oxygen species metabolic process GO:0072593 84 0.033
regulation of protein kinase activity GO:0045859 232 0.032
negative regulation of cellular amine metabolic process GO:0033239 1 0.031
spermatogenesis exchange of chromosomal proteins GO:0035093 4 0.030
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.030
innate immune response GO:0045087 157 0.029
negative regulation of organelle organization GO:0010639 90 0.029
negative regulation of cell cycle GO:0045786 123 0.029
negative regulation of phosphorylation GO:0042326 166 0.029
lateral inhibition GO:0046331 1 0.028
positive regulation of protein modification process GO:0031401 299 0.028
Human
histone modification GO:0016570 159 0.028
Human
regulation of mitosis GO:0007088 29 0.028
positive regulation of protein phosphorylation GO:0001934 242 0.027
positive regulation of nervous system development GO:0051962 221 0.027
positive regulation of meiotic cell cycle GO:0051446 15 0.026
regulation of apoptotic signaling pathway GO:2001233 197 0.026
cellular lipid metabolic process GO:0044255 323 0.026
regulation of mitotic cell cycle GO:0007346 126 0.026
negative regulation of protein modification process GO:0031400 163 0.026
multi multicellular organism process GO:0044706 109 0.025
membrane organization GO:0061024 245 0.025
regulation of cell cycle GO:0051726 281 0.025
spermatid development GO:0007286 108 0.025
negative regulation of immune system process GO:0002683 209 0.024
negative regulation of cellular component organization GO:0051129 194 0.024
wound healing spreading of epidermal cells GO:0035313 5 0.024
regulation of innate immune response GO:0045088 91 0.024
cellular response to lipid GO:0071396 145 0.024
meiotic chromosome segregation GO:0045132 19 0.023
fat cell differentiation GO:0045444 160 0.023
inorganic ion transmembrane transport GO:0098660 234 0.023
signal transduction by p53 class mediator GO:0072331 51 0.023
protein kinase b signaling GO:0043491 74 0.023
immune response regulating signaling pathway GO:0002764 125 0.022
reactive nitrogen species metabolic process GO:2001057 0 0.022
activation of immune response GO:0002253 138 0.022
epithelial cell development GO:0002064 159 0.022
microtubule based process GO:0007017 236 0.022
multi organism behavior GO:0051705 62 0.022
dna recombination GO:0006310 92 0.021
methylation GO:0032259 134 0.021
Human
regulation of membrane potential GO:0042391 192 0.021
mapk cascade GO:0000165 281 0.021
gene silencing GO:0016458 38 0.021
multicellular organismal signaling GO:0035637 91 0.020
inorganic cation transmembrane transport GO:0098662 207 0.020
oxidation reduction process GO:0055114 342 0.020
leukocyte mediated cytotoxicity GO:0001909 62 0.020
peptidyl amino acid modification GO:0018193 336 0.019
divalent metal ion transport GO:0070838 172 0.019
inflammatory response GO:0006954 244 0.019
regulation of peptidase activity GO:0052547 96 0.019
negative regulation of molecular function GO:0044092 258 0.019
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.019
cellular response to cytokine stimulus GO:0071345 189 0.019
reactive oxygen species biosynthetic process GO:1903409 8 0.018
regulation of neuron apoptotic process GO:0043523 122 0.018
cellular protein complex assembly GO:0043623 116 0.018
positive regulation of transferase activity GO:0051347 167 0.018
cell fate commitment GO:0045165 210 0.018
cellular chemical homeostasis GO:0055082 215 0.018
regulation of cell cycle process GO:0010564 160 0.018
posttranscriptional regulation of gene expression GO:0010608 155 0.018
Human
organ regeneration GO:0031100 2 0.018
negative regulation of cytokine production GO:0001818 84 0.018
mitotic cell cycle GO:0000278 195 0.018
positive regulation of protein kinase activity GO:0045860 144 0.018
wound healing spreading of cells GO:0044319 8 0.017
stem cell development GO:0048864 219 0.017
skeletal muscle organ development GO:0060538 163 0.017
regulation of cell motility GO:2000145 236 0.017
circulatory system process GO:0003013 197 0.017
cellular response to organonitrogen compound GO:0071417 145 0.017
positive regulation of apoptotic process GO:0043065 217 0.017
nucleosome assembly GO:0006334 7 0.017
regulation of organelle organization GO:0033043 289 0.017
Human
peptidyl lysine modification GO:0018205 77 0.016
modification dependent protein catabolic process GO:0019941 133 0.016
positive regulation of cell cycle GO:0045787 92 0.016
response to molecule of bacterial origin GO:0002237 143 0.016
nitrogen compound transport GO:0071705 271 0.016
regulation of proteolysis GO:0030162 164 0.016
positive regulation of homeostatic process GO:0032846 64 0.016
monocarboxylic acid metabolic process GO:0032787 191 0.016
regulation of cell cycle phase transition GO:1901987 77 0.016
cellular response to acid chemical GO:0071229 68 0.016
cellular response to estrogen stimulus GO:0071391 12 0.016
purine nucleotide metabolic process GO:0006163 302 0.016
response to testosterone GO:0033574 3 0.016
female gamete generation GO:0007292 74 0.016
regulation of binding GO:0051098 111 0.016
developmental maturation GO:0021700 193 0.016
regulation of erk1 and erk2 cascade GO:0070372 71 0.016
ear development GO:0043583 200 0.016
negative regulation of interleukin 5 production GO:0032714 4 0.015
cellular macromolecule catabolic process GO:0044265 206 0.015
endocytosis GO:0006897 168 0.015
blood circulation GO:0008015 195 0.015
regulation of chromatin organization GO:1902275 57 0.015
Human
cytoplasmic transport GO:0016482 234 0.015
transmission of nerve impulse GO:0019226 76 0.015
leukocyte apoptotic process GO:0071887 71 0.015
b cell activation GO:0042113 161 0.015
calcium ion transport GO:0006816 159 0.015
homeostasis of number of cells GO:0048872 210 0.015
muscle cell differentiation GO:0042692 261 0.015
positive regulation of cell death GO:0010942 224 0.014
negative regulation of proteolysis GO:0045861 74 0.014
macromolecular complex disassembly GO:0032984 43 0.014
regulation of lymphocyte activation GO:0051249 240 0.014
protein acylation GO:0043543 64 0.014
regulation of protein stability GO:0031647 52 0.014
Human
b cell proliferation GO:0042100 53 0.014
dephosphorylation GO:0016311 129 0.014
negative regulation of mitotic cell cycle GO:0045930 58 0.014
covalent chromatin modification GO:0016569 163 0.014
Human
compound eye development GO:0048749 1 0.014
response to growth factor GO:0070848 198 0.014
glial cell differentiation GO:0010001 131 0.014
regulation of reactive oxygen species metabolic process GO:2000377 40 0.014
protein modification by small protein conjugation or removal GO:0070647 207 0.014
response to organic cyclic compound GO:0014070 198 0.014
cytokinetic process GO:0032506 2 0.014
cell type specific apoptotic process GO:0097285 268 0.014
regulation of kinase activity GO:0043549 249 0.014
positive regulation of kinase activity GO:0033674 155 0.014
negative regulation of chromosome organization GO:2001251 30 0.014
binding of sperm to zona pellucida GO:0007339 34 0.014
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.014
regulation of chromosome organization GO:0033044 83 0.014
Human
striated muscle cell development GO:0055002 125 0.014
zymogen activation GO:0031638 41 0.014
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.014
maintenance of location GO:0051235 89 0.014
cellular response to oxidative stress GO:0034599 76 0.014
macromolecule catabolic process GO:0009057 281 0.014
regulation of vesicle mediated transport GO:0060627 139 0.014
regulation of tissue remodeling GO:0034103 38 0.014
mitochondrion organization GO:0007005 134 0.013
response to inorganic substance GO:0010035 96 0.013
organic acid biosynthetic process GO:0016053 86 0.013
regulation of cell division GO:0051302 76 0.013
macromolecule methylation GO:0043414 120 0.013
Human
regulation of multi organism process GO:0043900 111 0.013
regulation of protein processing GO:0070613 96 0.013
regulation of nuclear division GO:0051783 56 0.013
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.013
protein import GO:0017038 101 0.013
positive regulation of response to wounding GO:1903036 66 0.013
actin cytoskeleton organization GO:0030036 220 0.013
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.013
regulation of chromatin silencing GO:0031935 2 0.013
nucleotide metabolic process GO:0009117 332 0.013
regulation of hydrolase activity GO:0051336 246 0.013
small molecule biosynthetic process GO:0044283 132 0.013
response to decreased oxygen levels GO:0036293 59 0.013
cation transport GO:0006812 399 0.013
nucleoside phosphate metabolic process GO:0006753 338 0.013
protein targeting GO:0006605 143 0.013
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.013
protein ubiquitination GO:0016567 171 0.013
regulation of cell migration GO:0030334 219 0.013
striated muscle tissue development GO:0014706 293 0.013
divalent inorganic cation transport GO:0072511 178 0.013
organic hydroxy compound metabolic process GO:1901615 203 0.013
phagocytosis GO:0006909 66 0.013
positive regulation of cellular amine metabolic process GO:0033240 5 0.013
action potential GO:0001508 78 0.012
cell division GO:0051301 120 0.012
regulation of secretion GO:0051046 274 0.012
defense response to bacterium GO:0042742 119 0.012
natural killer cell inhibitory signaling pathway GO:0002769 2 0.012
negative regulation of intracellular signal transduction GO:1902532 167 0.012
anion transport GO:0006820 177 0.012
organelle localization GO:0051640 179 0.012
cellular response to hormone stimulus GO:0032870 150 0.012
positive regulation of intrinsic apoptotic signaling pathway GO:2001244 25 0.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.012
cell growth GO:0016049 130 0.012
Human
pattern recognition receptor signaling pathway GO:0002221 47 0.012
ubiquitin dependent protein catabolic process GO:0006511 129 0.012
cation transmembrane transport GO:0098655 266 0.012
positive regulation of leukocyte proliferation GO:0070665 73 0.012
sequestering of calcium ion GO:0051208 18 0.012
feeding behavior GO:0007631 62 0.012
positive regulation of defense response GO:0031349 124 0.012
oocyte construction GO:0007308 2 0.012
sensory perception GO:0007600 245 0.012
positive regulation of proteolysis GO:0045862 85 0.012
positive regulation of organelle organization GO:0010638 128 0.012
Human
anion transmembrane transport GO:0098656 71 0.012
rap protein signal transduction GO:0032486 3 0.012
regulation of lymphocyte proliferation GO:0050670 117 0.012
g protein coupled receptor signaling pathway GO:0007186 243 0.012
positive regulation of programmed cell death GO:0043068 218 0.012
myosin filament organization GO:0031033 3 0.011
organonitrogen compound biosynthetic process GO:1901566 192 0.011
negative regulation of cell proliferation GO:0008285 296 0.011
positive regulation of lymphocyte proliferation GO:0050671 70 0.011
regulation of cell growth GO:0001558 91 0.011
Human
cellular response to extracellular stimulus GO:0031668 81 0.011
negative regulation of protein processing GO:0010955 79 0.011
kidney development GO:0001822 213 0.011
positive regulation of cell cycle process GO:0090068 61 0.011
cytokine mediated signaling pathway GO:0019221 115 0.011
carbohydrate derivative biosynthetic process GO:1901137 183 0.011
production of molecular mediator of immune response GO:0002440 103 0.011
fatty acid metabolic process GO:0006631 121 0.011
peptidyl lysine acetylation GO:0018394 45 0.011
sensory organ morphogenesis GO:0090596 242 0.011
positive regulation of cell activation GO:0050867 158 0.011
purine nucleoside monophosphate metabolic process GO:0009126 81 0.011
protein modification by small protein conjugation GO:0032446 187 0.011
organic hydroxy compound biosynthetic process GO:1901617 77 0.011
adaptive immune response GO:0002250 155 0.011
enamel mineralization GO:0070166 7 0.011
leukocyte mediated immunity GO:0002443 174 0.011
regulation of intracellular transport GO:0032386 159 0.011
internal protein amino acid acetylation GO:0006475 42 0.011
multicellular organism growth GO:0035264 161 0.011
erk1 and erk2 cascade GO:0070371 77 0.011
cellular alcohol biosynthetic process GO:0044108 3 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.011
cellular response to steroid hormone stimulus GO:0071383 33 0.011
secondary metabolite catabolic process GO:0090487 1 0.011
regulation of protein catabolic process GO:0042176 108 0.010
regulation of cell projection organization GO:0031344 206 0.010
plasma membrane organization GO:0007009 90 0.010
leukocyte chemotaxis GO:0030595 69 0.010
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.010
lymphocyte proliferation GO:0046651 164 0.010
urogenital system development GO:0001655 261 0.010
cell maturation GO:0048469 127 0.010
nucleocytoplasmic transport GO:0006913 139 0.010
regulation of feeding behavior GO:0060259 3 0.010
myeloid cell differentiation GO:0030099 233 0.010
microtubule cytoskeleton organization GO:0000226 157 0.010
regulation of chromatin modification GO:1903308 57 0.010
Human
regulation of leukocyte mediated immunity GO:0002703 104 0.010
immune response activating signal transduction GO:0002757 116 0.010
protein localization to nucleus GO:0034504 121 0.010
activation of mapk activity GO:0000187 59 0.010
fatty acid derivative metabolic process GO:1901568 33 0.010
neuron apoptotic process GO:0051402 142 0.010
rna processing GO:0006396 105 0.010
regulation of protein localization GO:0032880 231 0.010
regulation of angiotensin metabolic process GO:0060177 4 0.010
carboxylic acid biosynthetic process GO:0046394 86 0.010
cellular response to molecule of fungal origin GO:0071226 2 0.010
myosin filament assembly GO:0031034 2 0.010
neuron death GO:0070997 154 0.010
positive regulation of cell development GO:0010720 237 0.010
regulation of cysteine type endopeptidase activity GO:2000116 65 0.010
proteasomal protein catabolic process GO:0010498 98 0.010

Hist1h1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.023
inherited metabolic disorder DOID:655 0 0.023
disease of anatomical entity DOID:7 0 0.020
gastrointestinal system disease DOID:77 0 0.020
nervous system disease DOID:863 0 0.017
sensory system disease DOID:0050155 0 0.016
eye and adnexa disease DOID:1492 0 0.016
central nervous system disease DOID:331 0 0.015
physical disorder DOID:0080015 0 0.015
immune system disease DOID:2914 0 0.012
mouth disease DOID:403 0 0.011
tooth disease DOID:1091 0 0.011
eye disease DOID:5614 0 0.011
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010
organ system cancer DOID:0050686 0 0.010