Mus musculus

41 known processes

Hmx3

H6 homeobox 3

(Aliases: Nkx-5.1,Nkx5-1,Nkx5.1)

Hmx3 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
paraxial mesodermal cell differentiation GO:0048342 2 0.999
carbon catabolite repression of transcription from rna polymerase ii promoter GO:0000437 1 0.999
metanephric dct cell differentiation GO:0072240 3 0.999
paraxial mesodermal cell fate commitment GO:0048343 2 0.996
embryonic organ morphogenesis GO:0048562 276 0.993
pyramidal neuron migration GO:0021852 1 0.992
brain segmentation GO:0035284 3 0.989
neurohypophysis development GO:0021985 2 0.986
ectoderm formation GO:0001705 3 0.982
somatotropin secreting cell differentiation GO:0060126 4 0.980
metanephric capsule specification GO:0072267 1 0.977
regulation of apoptotic process involved in outflow tract morphogenesis GO:1902256 2 0.977
sensory organ morphogenesis GO:0090596 242 0.974
regionalization GO:0003002 337 0.972
neuron migration GO:0001764 122 0.966
hindbrain formation GO:0021576 1 0.964
positive regulation of transcription from rna polymerase ii promoter by glucose GO:0000432 3 0.960
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development GO:0060528 4 0.956
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 4 0.953
mesodermal cell fate commitment GO:0001710 17 0.945
Worm
digestive system development GO:0055123 200 0.944
Worm
positive regulation of transcription by glucose GO:0046016 3 0.943
granulosa cell differentiation GO:0060014 1 0.940
hindbrain development GO:0030902 128 0.939
pattern specification involved in metanephros development GO:0072268 4 0.938
inner ear morphogenesis GO:0042472 101 0.937
regulation of vascular wound healing GO:0061043 2 0.934
loop of henle development GO:0072070 10 0.933
telencephalon development GO:0021537 186 0.930
renal capsule specification GO:0072130 1 0.928
glomerular mesangial cell differentiation GO:0072008 3 0.927
cerebellum formation GO:0021588 1 0.920
carbon catabolite activation of transcription GO:0045991 4 0.915
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.909
Worm
skeletal system development GO:0001501 356 0.906
renal capsule formation GO:0072129 1 0.905
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.887
midbrain hindbrain boundary morphogenesis GO:0021555 4 0.875
positive regulation of secondary heart field cardioblast proliferation GO:0072513 4 0.873
limbic system development GO:0021761 72 0.871
positive regulation of auditory receptor cell differentiation GO:0045609 1 0.868
mesangial cell differentiation GO:0072007 4 0.867
ear morphogenesis GO:0042471 118 0.864
metanephric capsule formation GO:0072266 1 0.860
digestive tract morphogenesis GO:0048546 147 0.859
Worm
proprioception GO:0019230 4 0.857
inner cell mass cell fate commitment GO:0001827 2 0.855
olfactory bulb development GO:0021772 30 0.854
cerebral cortex cell migration GO:0021795 44 0.851
neural crest cell development GO:0014032 48 0.846
metanephric capsule morphogenesis GO:0072265 1 0.846
negative regulation of transcription from rna polymerase ii promoter by glucose GO:0000433 1 0.844
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.841
myelination in peripheral nervous system GO:0022011 19 0.841
epithalamus development GO:0021538 2 0.840
cerebral cortex radially oriented cell migration GO:0021799 31 0.828
forebrain development GO:0030900 302 0.827
neuron fate specification GO:0048665 30 0.827
regulation of cell migration involved in sprouting angiogenesis GO:0090049 4 0.826
lung proximal distal axis specification GO:0061115 1 0.826
regulation of bmp signaling pathway GO:0030510 60 0.823
lung induction GO:0060492 3 0.822
metanephric loop of henle development GO:0072236 4 0.822
mesonephric duct formation GO:0072181 2 0.816
glomerular mesangial cell development GO:0072144 3 0.812
olfactory lobe development GO:0021988 32 0.809
negative regulation of apoptotic process involved in outflow tract morphogenesis GO:1902257 2 0.808
gland development GO:0048732 330 0.801
renal capsule morphogenesis GO:0072128 1 0.797
auditory receptor cell fate determination GO:0042668 3 0.795
planar cell polarity pathway involved in cardiac right atrium morphogenesis GO:0061349 2 0.795
rhombomere development GO:0021546 8 0.795
forebrain neuron differentiation GO:0021879 52 0.790
neuromuscular process controlling balance GO:0050885 59 0.785
epithelial mesenchymal signaling involved in prostate gland development GO:0060738 2 0.784
hypophysis morphogenesis GO:0048850 3 0.781
forebrain generation of neurons GO:0021872 63 0.773
formation of primary germ layer GO:0001704 77 0.773
Worm
midbrain hindbrain boundary maturation during brain development GO:0022004 1 0.770
ear development GO:0043583 200 0.768
regulation of neuron differentiation GO:0045664 281 0.767
bmp signaling pathway GO:0030509 93 0.765
endocrine system development GO:0035270 98 0.763
telencephalon cell migration GO:0022029 55 0.753
mesonephric duct morphogenesis GO:0072180 4 0.750
detection of glucose GO:0051594 1 0.743
cardiac chamber morphogenesis GO:0003206 93 0.741
somatotropin secreting cell development GO:0060133 2 0.740
appendage morphogenesis GO:0035107 149 0.735
rhombomere 5 development GO:0021571 4 0.735
neural tube patterning GO:0021532 43 0.733
regulation of auditory receptor cell differentiation GO:0045607 4 0.732
embryonic appendage morphogenesis GO:0035113 126 0.726
negative regulation of transcription by glucose GO:0045014 1 0.719
placenta development GO:0001890 140 0.716
diencephalon development GO:0021536 63 0.716
forebrain cell migration GO:0021885 58 0.715
epithelial tube morphogenesis GO:0060562 303 0.710
striated muscle tissue development GO:0014706 293 0.709
rhombomere morphogenesis GO:0021593 2 0.708
retinal ganglion cell axon guidance GO:0031290 18 0.706
glandular epithelial cell differentiation GO:0002067 38 0.705
prostate gland stromal morphogenesis GO:0060741 2 0.703
nephron epithelium development GO:0072009 92 0.703
kidney rudiment formation GO:0072003 3 0.696
mammary gland morphogenesis GO:0060443 54 0.695
regulation of transcription from rna polymerase ii promoter by glucose GO:0000430 3 0.694
nephric duct formation GO:0072179 4 0.693
positive regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation GO:2000081 1 0.690
cell fate specification GO:0001708 72 0.689
Worm
cardiac ventricle morphogenesis GO:0003208 50 0.686
forebrain anterior posterior pattern specification GO:0021797 5 0.685
central nervous system vasculogenesis GO:0022009 3 0.683
pattern specification involved in kidney development GO:0061004 8 0.669
semicircular canal formation GO:0060876 1 0.669
digestive tract development GO:0048565 190 0.663
Worm
ureteric bud morphogenesis GO:0060675 62 0.662
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.660
epithelial cell maturation involved in prostate gland development GO:0060743 4 0.648
forebrain neuron development GO:0021884 30 0.647
auditory receptor cell differentiation GO:0042491 37 0.640
ectodermal cell fate commitment GO:0001712 1 0.637
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.630
cell differentiation in hindbrain GO:0021533 24 0.627
establishment of organ orientation GO:0048561 1 0.624
positive regulation of fat cell proliferation GO:0070346 1 0.624
mesoderm formation GO:0001707 62 0.623
Worm
cardiac neural crest cell migration involved in outflow tract morphogenesis GO:0003253 3 0.622
rhombomere 2 development GO:0021568 2 0.618
renal interstitial fibroblast development GO:0072141 5 0.614
segmentation GO:0035282 93 0.614
midbrain hindbrain boundary maturation GO:0021732 1 0.611
adenohypophysis development GO:0021984 14 0.604
cerebral cortex development GO:0021987 86 0.603
positive regulation of inner ear receptor cell differentiation GO:2000982 1 0.601
branching morphogenesis of an epithelial tube GO:0048754 159 0.600
semicircular canal fusion GO:0060879 1 0.598
ventricular compact myocardium morphogenesis GO:0003223 2 0.597
inner cell mass cell differentiation GO:0001826 7 0.596
neuromuscular process GO:0050905 99 0.594
negative regulation of neuron differentiation GO:0045665 101 0.593
dct cell differentiation GO:0072069 3 0.591
kidney epithelium development GO:0072073 121 0.590
neuron projection guidance GO:0097485 141 0.589
trophectodermal cell differentiation GO:0001829 21 0.587
central nervous system morphogenesis GO:0021551 2 0.587
negative regulation of neuron projection development GO:0010977 50 0.587
uterus morphogenesis GO:0061038 2 0.586
central nervous system neuron differentiation GO:0021953 162 0.585
negative regulation of nervous system development GO:0051961 156 0.583
carbon catabolite regulation of transcription from rna polymerase ii promoter GO:0000429 4 0.583
thick ascending limb development GO:0072023 2 0.581
developmental maturation GO:0021700 193 0.581
negative regulation of cell development GO:0010721 169 0.578
macula densa development GO:0072024 1 0.577
positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0072108 3 0.576
artery development GO:0060840 53 0.574
androgen biosynthetic process GO:0006702 4 0.574
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.571
positive regulation of stem cell proliferation GO:2000648 59 0.568
stem cell maintenance GO:0019827 130 0.567
metanephros development GO:0001656 79 0.565
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation GO:0003257 3 0.564
negative regulation of hexokinase activity GO:1903300 4 0.562
renal system development GO:0072001 225 0.561
cell fate commitment GO:0045165 210 0.559
Worm
neural crest cell differentiation GO:0014033 54 0.559
mesenchyme morphogenesis GO:0072132 32 0.557
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.552
mesonephric tubule morphogenesis GO:0072171 63 0.552
dorsal ventral neural tube patterning GO:0021904 28 0.552
mesodermal cell differentiation GO:0048333 22 0.551
Worm
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000802 1 0.547
foregut regionalization GO:0060423 3 0.547
regulation of neuron projection development GO:0010975 169 0.546
mesenchymal cell development GO:0014031 93 0.545
positive regulation of cell migration involved in sprouting angiogenesis GO:0090050 3 0.543
rhombomere 3 morphogenesis GO:0021658 2 0.543
forebrain regionalization GO:0021871 25 0.538
distal tubule development GO:0072017 8 0.536
paraxial mesoderm morphogenesis GO:0048340 10 0.535
detection of monosaccharide stimulus GO:0034287 1 0.532
cardiac right atrium morphogenesis GO:0003213 3 0.529
embryonic placenta development GO:0001892 98 0.525
neural tube development GO:0021915 160 0.523
pancreatic pp cell fate commitment GO:0003329 2 0.521
ventral spinal cord interneuron fate commitment GO:0060579 14 0.519
camera type eye development GO:0043010 266 0.515
endodermal cell fate specification GO:0001714 4 0.511
apoptotic process involved in outflow tract morphogenesis GO:0003275 2 0.510
branching involved in ureteric bud morphogenesis GO:0001658 56 0.508
metanephric ascending thin limb development GO:0072218 2 0.508
submandibular salivary gland formation GO:0060661 1 0.502
establishment of planar polarity involved in nephron morphogenesis GO:0072046 1 0.491
renal capsule development GO:0072127 1 0.491
cochlea development GO:0090102 35 0.489
axon guidance GO:0007411 141 0.483
sensory system development GO:0048880 3 0.477
Zebrafish
renal system pattern specification GO:0072048 9 0.475
nephrogenic mesenchyme development GO:0072076 3 0.473
skeletal muscle cell differentiation GO:0035914 66 0.471
lateral line system development GO:0048925 1 0.469
Zebrafish
establishment or maintenance of neuroblast polarity GO:0045196 1 0.468
positive regulation of heart growth GO:0060421 18 0.468
regulation of cell cycle GO:0051726 281 0.466
mammary gland duct morphogenesis GO:0060603 38 0.466
positive regulation of nervous system development GO:0051962 221 0.466
spemann organizer formation at the anterior end of the primitive streak GO:0060064 1 0.465
midbrain hindbrain boundary development GO:0030917 9 0.464
apoptotic process involved in morphogenesis GO:0060561 25 0.464
hypothalamus cell differentiation GO:0021979 8 0.463
metanephric thick ascending limb development GO:0072233 2 0.463
hippocampus development GO:0021766 52 0.462
glomerular epithelial cell differentiation GO:0072311 10 0.462
muscle tissue morphogenesis GO:0060415 53 0.461
cardiac muscle tissue morphogenesis GO:0055008 44 0.457
lateral sprouting involved in mammary gland duct morphogenesis GO:0060599 2 0.457
axonogenesis GO:0007409 274 0.455
embryonic forelimb morphogenesis GO:0035115 32 0.454
glomerular endothelium development GO:0072011 2 0.454
astrocyte fate commitment GO:0060018 4 0.453
endocardial cushion to mesenchymal transition involved in heart valve formation GO:0003199 4 0.451
regulation of cardiac muscle tissue growth GO:0055021 26 0.451
renal tubule development GO:0061326 87 0.447
lung pattern specification process GO:0060432 1 0.445
carbon catabolite repression of transcription GO:0045013 1 0.443
endodermal cell fate commitment GO:0001711 12 0.441
angiogenesis GO:0001525 201 0.440
tertiary branching involved in mammary gland duct morphogenesis GO:0060748 3 0.440
striated muscle cell proliferation GO:0014855 39 0.437
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.434
cardiac muscle cell differentiation GO:0055007 69 0.434
axis elongation involved in somitogenesis GO:0090245 4 0.431
positive regulation of transcription initiation from rna polymerase ii promoter GO:0060261 5 0.431
forelimb morphogenesis GO:0035136 40 0.429
mesoderm morphogenesis GO:0048332 64 0.429
Worm
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process GO:2000763 1 0.423
respiratory tube development GO:0030323 167 0.422
stem cell development GO:0048864 219 0.421
negative regulation of mechanoreceptor differentiation GO:0045632 3 0.420
appendage development GO:0048736 166 0.420
negative regulation of detection of glucose GO:2000971 1 0.420
heart growth GO:0060419 45 0.413
mesonephric tubule formation GO:0072172 11 0.408
chromatin organization GO:0006325 206 0.405
endocrine pancreas development GO:0031018 29 0.404
skin morphogenesis GO:0043589 38 0.404
horizontal cell localization GO:0035852 1 0.402
vascular wound healing GO:0061042 3 0.401
ion transmembrane transport GO:0034220 361 0.398
embryonic skeletal system development GO:0048706 120 0.396
embryonic viscerocranium morphogenesis GO:0048703 8 0.396
muscle cell proliferation GO:0033002 52 0.395
limb morphogenesis GO:0035108 149 0.392
regulation of secretion GO:0051046 274 0.391
regulation of organ morphogenesis GO:2000027 144 0.389
Worm
embryonic skeletal system morphogenesis GO:0048704 91 0.389
pallium development GO:0021543 120 0.387
blood circulation GO:0008015 195 0.387
development of primary female sexual characteristics GO:0046545 73 0.387
cartilage development GO:0051216 140 0.386
motor neuron migration GO:0097475 4 0.385
renal tubule morphogenesis GO:0061333 72 0.383
skeletal system morphogenesis GO:0048705 203 0.382
pancreas development GO:0031016 57 0.381
mesenchymal cell differentiation GO:0048762 107 0.380
renal filtration cell differentiation GO:0061318 10 0.379
ectodermal cell differentiation GO:0010668 3 0.378
stem cell differentiation GO:0048863 268 0.378
metanephric distal convoluted tubule development GO:0072221 5 0.378
cell differentiation in spinal cord GO:0021515 53 0.378
nephron tubule development GO:0072080 84 0.375
epithelial cell differentiation involved in kidney development GO:0035850 23 0.374
regulation of cellular ketone metabolic process GO:0010565 66 0.373
somatic sex determination GO:0018993 2 0.371
regulation of cardiac muscle cell proliferation GO:0060043 23 0.369
positive regulation of cardiac muscle cell proliferation GO:0060045 15 0.368
planar cell polarity pathway involved in pericardium morphogenesis GO:0061354 2 0.367
hindlimb morphogenesis GO:0035137 42 0.365
cardiac muscle cell proliferation GO:0060038 31 0.362
regulation of ketone biosynthetic process GO:0010566 2 0.362
hair cell differentiation GO:0035315 40 0.361
cranial nerve development GO:0021545 41 0.361
visceral motor neuron differentiation GO:0021524 3 0.359
cell proliferation in forebrain GO:0021846 30 0.359
paramesonephric duct development GO:0061205 3 0.358
positive regulation of neuroblast proliferation GO:0002052 19 0.357
primitive streak formation GO:0090009 10 0.355
cochlea morphogenesis GO:0090103 22 0.353
central nervous system neuron development GO:0021954 67 0.353
embryonic heart tube morphogenesis GO:0003143 51 0.349
bronchiole morphogenesis GO:0060436 1 0.349
optic nerve structural organization GO:0021633 2 0.345
lateral motor column neuron migration GO:0097477 3 0.345
transdifferentiation GO:0060290 1 0.344
regulation of heart growth GO:0060420 31 0.342
respiratory system development GO:0060541 190 0.340
pituitary gland development GO:0021983 38 0.338
blastocyst development GO:0001824 80 0.336
myoblast differentiation involved in skeletal muscle regeneration GO:0014835 3 0.334
metanephric epithelium development GO:0072207 21 0.333
mesodermal to mesenchymal transition involved in gastrulation GO:0060809 1 0.329
circulatory system process GO:0003013 197 0.328
blood vessel remodeling GO:0001974 33 0.328
embryonic limb morphogenesis GO:0030326 126 0.326
ameboidal type cell migration GO:0001667 128 0.325
positive regulation of inositol phosphate biosynthetic process GO:0060732 2 0.325
cerebral cortex gabaergic interneuron differentiation GO:0021892 9 0.322
cerebral cortex radial glia guided migration GO:0021801 17 0.322
positive regulation of ureteric bud formation GO:0072107 3 0.322
planar cell polarity pathway involved in outflow tract morphogenesis GO:0061347 2 0.319
sensory perception of mechanical stimulus GO:0050954 107 0.316
mrna transcription from rna polymerase ii promoter GO:0042789 4 0.316
dendrite development GO:0016358 115 0.315
rhombomere 3 development GO:0021569 4 0.313
oviduct development GO:0060066 3 0.311
auditory receptor cell fate specification GO:0042667 1 0.311
positive regulation of anagen GO:0051885 1 0.311
morphogenesis of a branching structure GO:0001763 203 0.310
amine metabolic process GO:0009308 45 0.309
regulation of mesodermal cell fate specification GO:0042661 5 0.308
Worm
regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000800 1 0.307
central nervous system segmentation GO:0035283 3 0.307
mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis GO:0072309 3 0.307
cell proliferation in hindbrain GO:0021534 10 0.305
negative regulation of calcium ion dependent exocytosis GO:0045955 3 0.305
blastocyst formation GO:0001825 33 0.303
olfactory bulb interneuron differentiation GO:0021889 12 0.298
cell differentiation involved in kidney development GO:0061005 33 0.298
cardiac muscle tissue development GO:0048738 130 0.297
regulation of cell adhesion GO:0030155 154 0.296
positive regulation of neuron differentiation GO:0045666 141 0.294
positive regulation of organ growth GO:0046622 29 0.294
cell differentiation involved in metanephros development GO:0072202 12 0.293
hypothalamus development GO:0021854 16 0.293
cellular modified amino acid metabolic process GO:0006575 63 0.292
white fat cell proliferation GO:0070343 2 0.292
connective tissue development GO:0061448 179 0.291
small molecule biosynthetic process GO:0044283 132 0.291
fat cell differentiation GO:0045444 160 0.290
somitogenesis GO:0001756 69 0.288
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.288
ventricular cardiac muscle tissue development GO:0003229 38 0.288
cell maturation GO:0048469 127 0.287
tissue remodeling GO:0048771 102 0.286
wound healing GO:0042060 157 0.285
trachea cartilage morphogenesis GO:0060535 4 0.284
regulation of embryonic development GO:0045995 71 0.284
Worm
epithelial cell morphogenesis GO:0003382 41 0.284
regulation of retina development in camera type eye GO:1902866 3 0.283
immunoglobulin secretion involved in immune response GO:0002380 2 0.281
embryonic hindlimb morphogenesis GO:0035116 32 0.278
regulation of white fat cell proliferation GO:0070350 2 0.278
planar cell polarity pathway involved in ventricular septum morphogenesis GO:0061348 2 0.276
metanephric renal vesicle morphogenesis GO:0072283 12 0.274
cellular amino acid metabolic process GO:0006520 103 0.273
metanephric distal tubule development GO:0072235 5 0.272
otic placode formation GO:0043049 1 0.269
nephron tubule morphogenesis GO:0072078 68 0.269
mesenchymal stem cell maintenance involved in nephron morphogenesis GO:0072038 7 0.268
lymphocyte differentiation GO:0030098 242 0.268
tongue development GO:0043586 18 0.267
mesenchymal to epithelial transition GO:0060231 12 0.266
ascending thin limb development GO:0072021 2 0.266
lung morphogenesis GO:0060425 50 0.265
fibroblast growth factor receptor signaling pathway involved in mammary gland specification GO:0060595 2 0.261
skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration GO:0014834 3 0.258
spemann organizer formation GO:0060061 2 0.256
kidney development GO:0001822 213 0.254
cardiac muscle tissue growth GO:0055017 37 0.253
forebrain neuron fate commitment GO:0021877 13 0.253
multicellular organismal signaling GO:0035637 91 0.251
response to fibroblast growth factor GO:0071774 47 0.251
metanephric nephron epithelium development GO:0072243 19 0.249
blood vessel morphogenesis GO:0048514 285 0.249
nephron morphogenesis GO:0072028 69 0.249
preganglionic parasympathetic nervous system development GO:0021783 17 0.248
rna splicing GO:0008380 54 0.248
Mouse
morphogenesis of a branching epithelium GO:0061138 193 0.247
dopaminergic neuron differentiation GO:0071542 14 0.246
positive regulation of endothelial cell migration GO:0010595 12 0.245
corticotropin hormone secreting cell differentiation GO:0060128 3 0.244
lung field specification GO:0060424 3 0.244
metanephric nephron tubule epithelial cell differentiation GO:0072257 5 0.243
mesenchymal cell differentiation involved in lung development GO:0060915 2 0.243
regulation of ureteric bud formation GO:0072106 3 0.242
regulation of axon diameter GO:0031133 6 0.241
cellular response to fibroblast growth factor stimulus GO:0044344 47 0.241
embryonic heart tube development GO:0035050 65 0.240
olfactory bulb interneuron development GO:0021891 7 0.240
cerebral cortex gabaergic interneuron migration GO:0021853 6 0.239
regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0003339 5 0.239
vagus nerve morphogenesis GO:0021644 2 0.239
segment specification GO:0007379 15 0.238
metanephric nephron tubule formation GO:0072289 4 0.237
nerve development GO:0021675 67 0.237
endodermal cell fate determination GO:0007493 2 0.236
developmental induction GO:0031128 34 0.236
ectodermal placode morphogenesis GO:0071697 16 0.236
transmembrane transport GO:0055085 412 0.235
metanephric capsule development GO:0072213 1 0.234
regulation of high voltage gated calcium channel activity GO:1901841 2 0.233
pancreatic a cell fate commitment GO:0003326 2 0.233
positive regulation of epithelial cell proliferation GO:0050679 68 0.232
positive regulation of nephron tubule epithelial cell differentiation GO:2000768 1 0.232
protein secretion GO:0009306 111 0.232
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.230
regulation of mesenchymal cell proliferation GO:0010464 37 0.229
cell adhesion GO:0007155 329 0.228
positive regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901228 4 0.224
hair follicle morphogenesis GO:0031069 29 0.224
skin development GO:0043588 220 0.224
positive regulation of voltage gated calcium channel activity GO:1901387 2 0.224
embryonic eye morphogenesis GO:0048048 29 0.223
mitotic cell cycle process GO:1903047 159 0.222
Worm
paraxial mesoderm development GO:0048339 18 0.222
habenula development GO:0021986 2 0.221
regulation of anagen GO:0051884 1 0.221
renal vesicle induction GO:0072034 3 0.221
specification of organ identity GO:0010092 30 0.218
negative regulation of axon guidance GO:1902668 8 0.216
muscle tissue development GO:0060537 308 0.216
spinal cord motor neuron migration GO:0097476 4 0.215
negative regulation of glucokinase activity GO:0033132 4 0.215
regulation of fat cell proliferation GO:0070344 4 0.214
regulation of transcription by glucose GO:0046015 3 0.213
establishment of neuroblast polarity GO:0045200 1 0.212
positive regulation of cell development GO:0010720 237 0.211
odontogenesis of dentin containing tooth GO:0042475 66 0.211
fat cell proliferation GO:0070341 4 0.210
dichotomous subdivision of terminal units involved in ureteric bud branching GO:0060678 1 0.210
kidney morphogenesis GO:0060993 83 0.210
sclerotome development GO:0061056 4 0.210
epithelial cell maturation GO:0002070 15 0.210
immune effector process GO:0002252 321 0.208
metencephalon development GO:0022037 89 0.208
regulation of secretion by cell GO:1903530 249 0.207
negative regulation of prostatic bud formation GO:0060686 4 0.207
adult behavior GO:0030534 135 0.207
locus ceruleus development GO:0021703 1 0.207
establishment of spindle localization GO:0051293 19 0.206
Worm
retina development in camera type eye GO:0060041 119 0.206
nephron development GO:0072006 109 0.204
multicellular organism growth GO:0035264 161 0.202
regulation of transferase activity GO:0051338 263 0.200
female sex determination GO:0030237 1 0.200
positive regulation of angiogenesis GO:0045766 46 0.199
cellular amine metabolic process GO:0044106 44 0.199
somite rostral caudal axis specification GO:0032525 13 0.199
female somatic sex determination GO:0019101 1 0.197
regulation of ossification GO:0030278 112 0.197
cranial nerve structural organization GO:0021604 13 0.197
chromatin modification GO:0016568 187 0.196
regulation of apoptotic process involved in morphogenesis GO:1902337 10 0.195
negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072040 4 0.193
spinal cord development GO:0021510 81 0.193
regulation of detection of glucose GO:2000970 1 0.192
neuron projection extension GO:1990138 64 0.191
cardiac atrium development GO:0003230 24 0.191
regulation of organ growth GO:0046620 61 0.190
pronephric field specification GO:0039003 2 0.190
regulation of rna splicing GO:0043484 37 0.189
Mouse
mesenchyme development GO:0060485 152 0.188
mammary gland bud formation GO:0060615 2 0.187
cerebellar granule cell differentiation GO:0021707 9 0.183
sensory perception GO:0007600 245 0.181
negative regulation of axon extension GO:0030517 19 0.181
ventricular cardiac muscle tissue morphogenesis GO:0055010 32 0.180
neural precursor cell proliferation GO:0061351 121 0.179
female genitalia morphogenesis GO:0048807 3 0.178
positive regulation of white fat cell proliferation GO:0070352 1 0.178
metanephric nephron development GO:0072210 34 0.177
cell fate determination GO:0001709 32 0.177
regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation GO:2000079 1 0.177
nephron tubule formation GO:0072079 20 0.177
establishment of planar polarity involved in neural tube closure GO:0090177 15 0.177
rna processing GO:0006396 105 0.175
Mouse
positive regulation of cell cycle GO:0045787 92 0.175
mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0003337 9 0.174
positive regulation of cardiac muscle tissue growth GO:0055023 15 0.173
mammary placode formation GO:0060596 4 0.173
apoptotic process involved in development GO:1902742 28 0.172
embryonic epithelial tube formation GO:0001838 130 0.171
negative regulation of cardiac chamber morphogenesis GO:1901220 2 0.170
neural crest cell migration GO:0001755 32 0.170
epithelial cell development GO:0002064 159 0.170
regulation of asymmetric cell division GO:0009786 4 0.170
neuron fate determination GO:0048664 9 0.170
regulation of blood circulation GO:1903522 93 0.169
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.169
histone modification GO:0016570 159 0.169
cardiac cell fate determination GO:0060913 2 0.168
sensory neuron axon guidance GO:0097374 3 0.168
neural tube closure GO:0001843 90 0.168
fibroblast growth factor production GO:0090269 4 0.167
establishment or maintenance of polarity of embryonic epithelium GO:0016332 1 0.166
organelle localization GO:0051640 179 0.165
Worm

Hmx3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.193
nervous system disease DOID:863 0 0.193