Mus musculus

7 known processes

Hps3

Hermansky-Pudlak syndrome 3 homolog (human)

(Aliases: coa)

Hps3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
pigment accumulation GO:0043476 1 0.925
microtubule based movement GO:0007018 84 0.337
microtubule based transport GO:0010970 50 0.297
vesicle localization GO:0051648 86 0.290
coagulation GO:0050817 78 0.261
establishment of melanosome localization GO:0032401 11 0.251
blood coagulation GO:0007596 76 0.245
pigment granule localization GO:0051875 13 0.191
vesicle organization GO:0016050 60 0.185
regulation of natural killer cell activation GO:0032814 22 0.170
hemostasis GO:0007599 78 0.167
synaptic vesicle localization GO:0097479 59 0.136
wound healing GO:0042060 157 0.134
anterograde axon cargo transport GO:0008089 20 0.130
establishment of organelle localization GO:0051656 122 0.125
melanosome localization GO:0032400 12 0.119
anterograde synaptic vesicle transport GO:0048490 15 0.109
melanosome transport GO:0032402 11 0.106
axon cargo transport GO:0008088 33 0.099
organelle localization GO:0051640 179 0.097
membrane organization GO:0061024 245 0.091
regulation of body fluid levels GO:0050878 162 0.082
secretion of lysosomal enzymes GO:0033299 6 0.082
positive regulation of lymphocyte activation GO:0051251 140 0.081
natural killer cell activation GO:0030101 44 0.080
pigment granule transport GO:0051904 12 0.071
pigmentation GO:0043473 71 0.062
regulation of lymphocyte activation GO:0051249 240 0.062
regulation of cell activation GO:0050865 289 0.062
positive regulation of natural killer cell activation GO:0032816 15 0.061
melanosome organization GO:0032438 8 0.056
organonitrogen compound catabolic process GO:1901565 264 0.052
cellular pigmentation GO:0033059 20 0.051
synaptic transmission GO:0007268 329 0.051
cytoplasmic transport GO:0016482 234 0.050
pigment cell differentiation GO:0050931 27 0.049
melanocyte differentiation GO:0030318 25 0.048
cellular amino acid metabolic process GO:0006520 103 0.048
positive regulation of cell activation GO:0050867 158 0.046
establishment of synaptic vesicle localization GO:0097480 57 0.044
nitrogen compound transport GO:0071705 271 0.044
establishment of vesicle localization GO:0051650 81 0.044
cellular lipid metabolic process GO:0044255 323 0.043
developmental pigmentation GO:0048066 40 0.042
cellular nitrogen compound catabolic process GO:0044270 280 0.041
regulation of cellular amino acid metabolic process GO:0006521 5 0.040
cation transport GO:0006812 399 0.040
synaptic vesicle transport GO:0048489 57 0.039
secretory granule organization GO:0033363 20 0.039
cellular amine metabolic process GO:0044106 44 0.039
microtubule based process GO:0007017 236 0.038
transmembrane transport GO:0055085 412 0.038
nucleotide metabolic process GO:0009117 332 0.037
organic cyclic compound catabolic process GO:1901361 295 0.037
regulation of secretion by cell GO:1903530 249 0.036
cellular macromolecule catabolic process GO:0044265 206 0.036
carbohydrate derivative catabolic process GO:1901136 231 0.036
aromatic compound catabolic process GO:0019439 286 0.035
retina development in camera type eye GO:0060041 119 0.035
protein secretion GO:0009306 111 0.035
purine ribonucleotide metabolic process GO:0009150 290 0.035
protein modification by small protein conjugation GO:0032446 187 0.035
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.034
protein ubiquitination GO:0016567 171 0.033
nucleoside phosphate metabolic process GO:0006753 338 0.033
lipid biosynthetic process GO:0008610 179 0.033
regulation of cellular ketone metabolic process GO:0010565 66 0.033
amine metabolic process GO:0009308 45 0.033
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.032
cation transmembrane transport GO:0098655 266 0.032
protein targeting GO:0006605 143 0.032
cellular protein catabolic process GO:0044257 155 0.031
lytic vacuole organization GO:0080171 21 0.031
camera type eye development GO:0043010 266 0.030
positive regulation of cellular amine metabolic process GO:0033240 5 0.030
purine containing compound metabolic process GO:0072521 311 0.030
heterocycle catabolic process GO:0046700 280 0.030
macromolecule catabolic process GO:0009057 281 0.029
dna metabolic process GO:0006259 303 0.029
ribonucleoside metabolic process GO:0009119 245 0.029
neuromuscular process GO:0050905 99 0.029
cellular homeostasis GO:0019725 240 0.028
nucleobase containing small molecule metabolic process GO:0055086 352 0.028
glycosyl compound metabolic process GO:1901657 246 0.028
cytokine production GO:0001816 319 0.027
nucleoside metabolic process GO:0009116 246 0.027
ribonucleotide metabolic process GO:0009259 291 0.027
nucleoside phosphate catabolic process GO:1901292 222 0.027
purine nucleoside metabolic process GO:0042278 241 0.027
organic hydroxy compound metabolic process GO:1901615 203 0.027
ribonucleoside triphosphate metabolic process GO:0009199 220 0.027
purine nucleotide metabolic process GO:0006163 302 0.027
ribonucleotide catabolic process GO:0009261 208 0.026
nucleoside catabolic process GO:0009164 206 0.026
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.025
protein modification by small protein conjugation or removal GO:0070647 207 0.025
organophosphate catabolic process GO:0046434 232 0.025
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.025
ribose phosphate metabolic process GO:0019693 291 0.025
regulation of organelle organization GO:0033043 289 0.024
axonogenesis GO:0007409 274 0.024
lipid localization GO:0010876 126 0.024
cellular ketone metabolic process GO:0042180 84 0.024
regulation of cellular amine metabolic process GO:0033238 20 0.024
purine nucleoside catabolic process GO:0006152 205 0.024
phospholipid metabolic process GO:0006644 87 0.024
neurotransmitter transport GO:0006836 76 0.023
regulation of protein localization GO:0032880 231 0.023
regulation of pigment cell differentiation GO:0050932 7 0.023
nucleoside triphosphate metabolic process GO:0009141 230 0.022
developmental maturation GO:0021700 193 0.022
regulation of neurotransmitter levels GO:0001505 87 0.022
single organism cell adhesion GO:0098602 156 0.022
nucleotide catabolic process GO:0009166 217 0.022
protein catabolic process GO:0030163 221 0.022
organonitrogen compound biosynthetic process GO:1901566 192 0.022
establishment of pigment granule localization GO:0051905 12 0.021
skeletal system morphogenesis GO:0048705 203 0.021
membrane fusion GO:0061025 38 0.021
purine ribonucleotide catabolic process GO:0009154 208 0.021
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.021
carbohydrate derivative biosynthetic process GO:1901137 183 0.021
reactive oxygen species metabolic process GO:0072593 84 0.021
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.021
small gtpase mediated signal transduction GO:0007264 97 0.020
inorganic cation transmembrane transport GO:0098662 207 0.020
ribonucleoside catabolic process GO:0042454 206 0.020
vacuole organization GO:0007033 38 0.020
actin cytoskeleton organization GO:0030036 220 0.020
glycosyl compound catabolic process GO:1901658 206 0.020
neuroepithelial cell differentiation GO:0060563 37 0.020
regulation of ion transport GO:0043269 215 0.019
chemotaxis GO:0006935 247 0.019
modification dependent macromolecule catabolic process GO:0043632 133 0.019
response to growth factor GO:0070848 198 0.019
apoptotic signaling pathway GO:0097190 306 0.019
purine nucleoside triphosphate metabolic process GO:0009144 226 0.019
mapk cascade GO:0000165 281 0.019
ossification GO:0001503 216 0.019
peptidyl amino acid modification GO:0018193 336 0.019
ras protein signal transduction GO:0007265 77 0.019
purine ribonucleoside metabolic process GO:0046128 241 0.018
organic hydroxy compound transport GO:0015850 93 0.018
methylation GO:0032259 134 0.018
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.018
negative regulation of phosphate metabolic process GO:0045936 184 0.018
purine nucleotide catabolic process GO:0006195 211 0.018
anion transport GO:0006820 177 0.018
skeletal system development GO:0001501 356 0.018
positive regulation of protein modification process GO:0031401 299 0.018
glycoprotein metabolic process GO:0009100 116 0.018
intracellular protein transport GO:0006886 204 0.018
eye pigmentation GO:0048069 3 0.018
fertilization GO:0009566 127 0.018
cytoskeleton dependent intracellular transport GO:0030705 50 0.018
modification dependent protein catabolic process GO:0019941 133 0.018
regulation of mapk cascade GO:0043408 248 0.018
muscle cell differentiation GO:0042692 261 0.018
purine nucleoside triphosphate catabolic process GO:0009146 203 0.018
purine containing compound catabolic process GO:0072523 213 0.017
purine ribonucleoside catabolic process GO:0046130 205 0.017
regulation of membrane potential GO:0042391 192 0.017
nucleoside triphosphate catabolic process GO:0009143 205 0.017
response to radiation GO:0009314 165 0.017
ubiquitin dependent protein catabolic process GO:0006511 129 0.017
ribonucleoside triphosphate catabolic process GO:0009203 199 0.017
inorganic ion transmembrane transport GO:0098660 234 0.017
negative regulation of protein metabolic process GO:0051248 282 0.017
regulation of cellular catabolic process GO:0031329 242 0.017
establishment of protein localization to organelle GO:0072594 118 0.017
lysosome organization GO:0007040 21 0.016
immune effector process GO:0002252 321 0.016
regulation of t cell activation GO:0050863 170 0.016
regulation of cell projection organization GO:0031344 206 0.016
positive regulation of cell death GO:0010942 224 0.016
cognition GO:0050890 149 0.016
respiratory system development GO:0060541 190 0.016
male gamete generation GO:0048232 285 0.016
neuromuscular process controlling balance GO:0050885 59 0.016
endocytosis GO:0006897 168 0.016
regulation of endocytosis GO:0030100 69 0.016
regulation of hydrolase activity GO:0051336 246 0.016
rho protein signal transduction GO:0007266 32 0.016
sensory perception GO:0007600 245 0.016
ion transmembrane transport GO:0034220 361 0.016
compound eye development GO:0048749 1 0.016
regulation of secretion GO:0051046 274 0.016
leukocyte migration GO:0050900 124 0.016
regulation of transferase activity GO:0051338 263 0.016
positive regulation of protein phosphorylation GO:0001934 242 0.016
cation homeostasis GO:0055080 212 0.015
organic anion transport GO:0015711 137 0.015
regulation of nucleotide metabolic process GO:0006140 169 0.015
platelet activation GO:0030168 40 0.015
muscle tissue development GO:0060537 308 0.015
regulation of proteolysis GO:0030162 164 0.015
innate immune response GO:0045087 157 0.015
regulation of neuron differentiation GO:0045664 281 0.015
alcohol metabolic process GO:0006066 116 0.015
glycerolipid metabolic process GO:0046486 122 0.015
oxidation reduction process GO:0055114 342 0.015
t cell mediated immunity GO:0002456 50 0.015
cellular protein complex assembly GO:0043623 116 0.015
negative regulation of cellular amine metabolic process GO:0033239 1 0.014
membrane lipid metabolic process GO:0006643 53 0.014
cellular ion homeostasis GO:0006873 165 0.014
multicellular organismal signaling GO:0035637 91 0.014
urogenital system development GO:0001655 261 0.014
pigment granule organization GO:0048753 9 0.014
negative regulation of phosphorus metabolic process GO:0010563 184 0.014
neuronal action potential GO:0019228 54 0.014
defense response to other organism GO:0098542 197 0.014
protein localization to organelle GO:0033365 185 0.014
posttranscriptional regulation of gene expression GO:0010608 155 0.014
negative regulation of cellular component organization GO:0051129 194 0.014
adult behavior GO:0030534 135 0.014
organophosphate biosynthetic process GO:0090407 122 0.013
divalent metal ion transport GO:0070838 172 0.013
glycoprotein biosynthetic process GO:0009101 89 0.013
glycerophospholipid metabolic process GO:0006650 71 0.013
response to organonitrogen compound GO:0010243 246 0.013
cell adhesion GO:0007155 329 0.013
negative regulation of phosphorylation GO:0042326 166 0.013
reactive oxygen species biosynthetic process GO:1903409 8 0.013
ear development GO:0043583 200 0.013
response to organic cyclic compound GO:0014070 198 0.013
epithelial tube morphogenesis GO:0060562 303 0.013
cellular chemical homeostasis GO:0055082 215 0.013
cellular response to growth factor stimulus GO:0071363 197 0.013
protein processing GO:0016485 163 0.013
response to acid chemical GO:0001101 111 0.013
small molecule biosynthetic process GO:0044283 132 0.013
organic acid transport GO:0015849 101 0.013
single fertilization GO:0007338 82 0.013
regulation of establishment of protein localization GO:0070201 181 0.013
cellular metal ion homeostasis GO:0006875 151 0.013
regulation of cytokine production GO:0001817 266 0.013
regulation of voltage gated calcium channel activity GO:1901385 4 0.013
b cell activation GO:0042113 161 0.013
nucleocytoplasmic transport GO:0006913 139 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.013
adaptive immune response GO:0002250 155 0.013
regulation of purine nucleotide metabolic process GO:1900542 169 0.012
hematopoietic progenitor cell differentiation GO:0002244 143 0.012
positive regulation of transferase activity GO:0051347 167 0.012
lung development GO:0030324 164 0.012
purine nucleoside monophosphate metabolic process GO:0009126 81 0.012
regulation of neuron apoptotic process GO:0043523 122 0.012
stem cell differentiation GO:0048863 268 0.012
negative regulation of cell development GO:0010721 169 0.012
negative regulation of molecular function GO:0044092 258 0.012
carboxylic acid transport GO:0046942 100 0.012
embryonic organ morphogenesis GO:0048562 276 0.012
regulation of kinase activity GO:0043549 249 0.012
defense response to bacterium GO:0042742 119 0.012
nucleoside monophosphate metabolic process GO:0009123 85 0.012
divalent inorganic cation transport GO:0072511 178 0.012
carboxylic acid biosynthetic process GO:0046394 86 0.012
lymphocyte proliferation GO:0046651 164 0.012
muscle system process GO:0003012 141 0.012
regulation of leukocyte mediated immunity GO:0002703 104 0.012
t cell activation GO:0042110 289 0.012
cellular alcohol biosynthetic process GO:0044108 3 0.012
regulation of vesicle mediated transport GO:0060627 139 0.012
positive regulation of secretion GO:0051047 130 0.012
respiratory tube development GO:0030323 167 0.012
blood circulation GO:0008015 195 0.012
regulation of cellular component biogenesis GO:0044087 181 0.012
morphogenesis of a branching structure GO:0001763 203 0.012
sequestering of metal ion GO:0051238 19 0.012
regulation of cytoskeleton organization GO:0051493 122 0.012
spermatogenesis GO:0007283 284 0.012
ribonucleoside monophosphate metabolic process GO:0009161 80 0.012
response to light stimulus GO:0009416 135 0.012
organic hydroxy compound biosynthetic process GO:1901617 77 0.012
cellular response to lipid GO:0071396 145 0.012
positive regulation of programmed cell death GO:0043068 218 0.012
regulation of reactive oxygen species metabolic process GO:2000377 40 0.011
gtp metabolic process GO:0046039 144 0.011
chromatin modification GO:0016568 187 0.011
tube formation GO:0035148 140 0.011
positive regulation of mapk cascade GO:0043410 170 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.011
cell type specific apoptotic process GO:0097285 268 0.011
stem cell development GO:0048864 219 0.011
digestive system development GO:0055123 200 0.011
carbohydrate metabolic process GO:0005975 230 0.011
kidney development GO:0001822 213 0.011
cellular carbohydrate metabolic process GO:0044262 119 0.011
learning or memory GO:0007611 148 0.011
regulation of apoptotic signaling pathway GO:2001233 197 0.011
regulation of protein catabolic process GO:0042176 108 0.011
response to oxidative stress GO:0006979 123 0.011
response to inorganic substance GO:0010035 96 0.011
extrinsic apoptotic signaling pathway GO:0097191 126 0.011
response to lipopolysaccharide GO:0032496 128 0.011
regulation of neuron death GO:1901214 134 0.011
stem cell maintenance GO:0019827 130 0.011
positive regulation of cellular catabolic process GO:0031331 148 0.011
transmission of nerve impulse GO:0019226 76 0.011
lymphocyte mediated immunity GO:0002449 139 0.011
proteasomal protein catabolic process GO:0010498 98 0.011
sequestering of calcium ion GO:0051208 18 0.011
platelet aggregation GO:0070527 20 0.011
organelle assembly GO:0070925 177 0.011
positive regulation of apoptotic process GO:0043065 217 0.011
protein maturation GO:0051604 176 0.011
sodium ion transport GO:0006814 73 0.011
regulation of cell cycle GO:0051726 281 0.011
reactive nitrogen species metabolic process GO:2001057 0 0.011
rna processing GO:0006396 105 0.011
tissue remodeling GO:0048771 102 0.011
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.011
regulation of nucleoside metabolic process GO:0009118 130 0.011
production of molecular mediator of immune response GO:0002440 103 0.011
regulation of protein transport GO:0051223 163 0.011
mitochondrion organization GO:0007005 134 0.011
glucose homeostasis GO:0042593 128 0.010
sulfur compound metabolic process GO:0006790 100 0.010
regulation of b cell activation GO:0050864 81 0.010
dopamine transport GO:0015872 15 0.010
maintenance of location GO:0051235 89 0.010
cellular response to lipopolysaccharide GO:0071222 77 0.010
lipid transport GO:0006869 98 0.010
nucleoside monophosphate catabolic process GO:0009125 59 0.010
negative regulation of cell proliferation GO:0008285 296 0.010
monosaccharide metabolic process GO:0005996 106 0.010
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.010
covalent chromatin modification GO:0016569 163 0.010
g protein coupled receptor signaling pathway GO:0007186 243 0.010
protein localization to membrane GO:0072657 108 0.010
chromatin organization GO:0006325 206 0.010
connective tissue development GO:0061448 179 0.010
leukocyte differentiation GO:0002521 342 0.010
response to extracellular stimulus GO:0009991 127 0.010
cellular response to cytokine stimulus GO:0071345 189 0.010
neuron apoptotic process GO:0051402 142 0.010
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.010
regulation of hormone levels GO:0010817 211 0.010
regulation of lymphocyte mediated immunity GO:0002706 84 0.010
nuclear transport GO:0051169 139 0.010
negative regulation of cell activation GO:0050866 111 0.010
endomembrane system organization GO:0010256 147 0.010
sphingolipid metabolic process GO:0006665 45 0.010
protein localization to nucleus GO:0034504 121 0.010
small molecule catabolic process GO:0044282 71 0.010
regulation of nucleotide catabolic process GO:0030811 122 0.010
morphogenesis of embryonic epithelium GO:0016331 159 0.010
regulation of leukocyte differentiation GO:1902105 159 0.010

Hps3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.030
inherited metabolic disorder DOID:655 0 0.030
central nervous system disease DOID:331 0 0.028
disease of anatomical entity DOID:7 0 0.028
nervous system disease DOID:863 0 0.028
musculoskeletal system disease DOID:17 0 0.011
connective tissue disease DOID:65 0 0.011
bone disease DOID:0080001 0 0.010