|
small molecule catabolic process
|
GO:0044282 |
71 |
0.466
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.215
|
|
|
carboxylic acid catabolic process
|
GO:0046395 |
51 |
0.206
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.199
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.198
|
Fly |
|
sulfur compound metabolic process
|
GO:0006790 |
100 |
0.197
|
Fly |
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.193
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.163
|
Human Rat Fly |
|
apoptotic mitochondrial changes
|
GO:0008637 |
48 |
0.161
|
|
|
alpha amino acid metabolic process
|
GO:1901605 |
59 |
0.141
|
|
|
cellular aldehyde metabolic process
|
GO:0006081 |
12 |
0.141
|
|
|
cellular modified amino acid metabolic process
|
GO:0006575 |
63 |
0.134
|
|
|
alcohol metabolic process
|
GO:0006066 |
116 |
0.111
|
Fly |
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.095
|
Fly |
|
glutathione metabolic process
|
GO:0006749 |
16 |
0.094
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.089
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.081
|
|
|
organic acid catabolic process
|
GO:0016054 |
51 |
0.079
|
|
|
alpha amino acid biosynthetic process
|
GO:1901607 |
15 |
0.074
|
|
|
positive regulation of cellular respiration
|
GO:1901857 |
3 |
0.061
|
|
|
protein tetramerization
|
GO:0051262 |
23 |
0.061
|
Rat |
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.059
|
|
|
peptide metabolic process
|
GO:0006518 |
46 |
0.056
|
|
|
acyl coa metabolic process
|
GO:0006637 |
19 |
0.054
|
Fly |
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.052
|
|
|
cellular amino acid biosynthetic process
|
GO:0008652 |
22 |
0.052
|
|
|
cofactor metabolic process
|
GO:0051186 |
80 |
0.049
|
Fly |
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.046
|
|
|
regulation of oxidative phosphorylation
|
GO:0002082 |
6 |
0.046
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.045
|
|
|
cellular lipid catabolic process
|
GO:0044242 |
52 |
0.045
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.045
|
|
|
lipid catabolic process
|
GO:0016042 |
69 |
0.044
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.039
|
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.038
|
|
|
protein processing
|
GO:0016485 |
163 |
0.037
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.035
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.034
|
|
|
removal of superoxide radicals
|
GO:0019430 |
12 |
0.033
|
|
|
response to oxygen levels
|
GO:0070482 |
62 |
0.033
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.032
|
Fly |
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.031
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
108 |
0.030
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.030
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.030
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.029
|
|
|
mitochondrial transport
|
GO:0006839 |
36 |
0.029
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.029
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.028
|
|
|
fatty acid beta oxidation
|
GO:0006635 |
16 |
0.028
|
|
|
cellular amide metabolic process
|
GO:0043603 |
58 |
0.028
|
|
|
negative regulation of protein sumoylation
|
GO:0033234 |
1 |
0.028
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.028
|
Fly |
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.028
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.027
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.027
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.027
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.027
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.026
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
11 |
0.026
|
|
|
regulation of removal of superoxide radicals
|
GO:2000121 |
4 |
0.026
|
|
|
positive regulation of interleukin 8 production
|
GO:0032757 |
2 |
0.026
|
|
|
response to oxygen radical
|
GO:0000305 |
16 |
0.026
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
90 |
0.026
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.026
|
|
|
interleukin 8 production
|
GO:0032637 |
4 |
0.025
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.025
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.025
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.024
|
|
|
negative regulation of protein processing
|
GO:0010955 |
79 |
0.024
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.023
|
|
|
regulation of interleukin 8 production
|
GO:0032677 |
3 |
0.023
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.023
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.023
|
|
|
dopamine uptake involved in synaptic transmission
|
GO:0051583 |
4 |
0.023
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.023
|
|
|
ketone catabolic process
|
GO:0042182 |
3 |
0.023
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.023
|
|
|
response to hypoxia
|
GO:0001666 |
58 |
0.022
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.022
|
|
|
primary alcohol metabolic process
|
GO:0034308 |
11 |
0.022
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.022
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.022
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.021
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.021
|
|
|
protein oxidation
|
GO:0018158 |
2 |
0.021
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.021
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.021
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.021
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.021
|
Fly |
|
xenobiotic catabolic process
|
GO:0042178 |
1 |
0.021
|
|
|
renal system development
|
GO:0072001 |
225 |
0.020
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.020
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.020
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.019
|
|
|
fatty acid metabolic process
|
GO:0006631 |
121 |
0.019
|
Fly |
|
retinoid metabolic process
|
GO:0001523 |
24 |
0.019
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.019
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.019
|
|
|
kidney development
|
GO:0001822 |
213 |
0.019
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.019
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.019
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.018
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.018
|
|
|
regulation of receptor activity
|
GO:0010469 |
41 |
0.018
|
|
|
regulation of oxidoreductase activity
|
GO:0051341 |
15 |
0.018
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.018
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.018
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.018
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.017
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.017
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.017
|
|
|
regulation of generation of precursor metabolites and energy
|
GO:0043467 |
38 |
0.017
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.017
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.017
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.017
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.017
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.017
|
|
|
mitochondrial electron transport nadh to ubiquinone
|
GO:0006120 |
4 |
0.016
|
|
|
response to reactive oxygen species
|
GO:0000302 |
56 |
0.016
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.016
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.016
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.016
|
|
|
organic hydroxy compound biosynthetic process
|
GO:1901617 |
77 |
0.016
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.016
|
|
|
protein homooligomerization
|
GO:0051260 |
43 |
0.016
|
Rat |
|
inflammatory response
|
GO:0006954 |
244 |
0.016
|
|
|
terpenoid metabolic process
|
GO:0006721 |
25 |
0.016
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.016
|
|
|
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway
|
GO:1902176 |
4 |
0.016
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
98 |
0.016
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.016
|
|
|
regulation of mitochondrion organization
|
GO:0010821 |
27 |
0.016
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.016
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.016
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.015
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
61 |
0.015
|
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.015
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
93 |
0.015
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.015
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.015
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.015
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.014
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.014
|
|
|
lipid oxidation
|
GO:0034440 |
29 |
0.014
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.014
|
Rat |
|
catecholamine uptake involved in synaptic transmission
|
GO:0051934 |
4 |
0.014
|
|
|
cation transport
|
GO:0006812 |
399 |
0.014
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.014
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.013
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.013
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
128 |
0.013
|
|
|
cellular response to hypoxia
|
GO:0071456 |
17 |
0.013
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
59 |
0.013
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.013
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.013
|
|
|
alpha amino acid catabolic process
|
GO:1901606 |
18 |
0.013
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.013
|
|
|
gland development
|
GO:0048732 |
330 |
0.013
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.013
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.013
|
|
|
adult behavior
|
GO:0030534 |
135 |
0.013
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.013
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.013
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.012
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
207 |
0.012
|
|
|
regulation of neurotransmitter levels
|
GO:0001505 |
87 |
0.012
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.012
|
|
|
regulation of cellular response to oxidative stress
|
GO:1900407 |
19 |
0.012
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.012
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
132 |
0.012
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.012
|
|
|
female gamete generation
|
GO:0007292 |
74 |
0.012
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.012
|
|
|
cation transmembrane transport
|
GO:0098655 |
266 |
0.012
|
|
|
regulation of oxidative phosphorylation uncoupler activity
|
GO:2000275 |
3 |
0.012
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.012
|
|
|
action potential
|
GO:0001508 |
78 |
0.012
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.012
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.012
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
40 |
0.012
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.012
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.012
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.012
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.011
|
|
|
catecholamine uptake
|
GO:0090493 |
4 |
0.011
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.011
|
|
|
lipid modification
|
GO:0030258 |
65 |
0.011
|
|
|
negative regulation of nitric oxide synthase biosynthetic process
|
GO:0051771 |
1 |
0.011
|
|
|
dopamine uptake
|
GO:0090494 |
4 |
0.011
|
|
|
hormone metabolic process
|
GO:0042445 |
86 |
0.011
|
Fly |
|
negative regulation of intracellular transport
|
GO:0032387 |
38 |
0.011
|
|
|
gonad development
|
GO:0008406 |
141 |
0.011
|
Rat |
|
negative regulation of mitochondrion organization
|
GO:0010823 |
9 |
0.011
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.011
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.011
|
|
|
oogenesis
|
GO:0048477 |
56 |
0.011
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.011
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.011
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.011
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
46 |
0.011
|
|
|
membrane depolarization
|
GO:0051899 |
64 |
0.011
|
|
|
fatty acid catabolic process
|
GO:0009062 |
25 |
0.010
|
|
|
positive regulation of protein homodimerization activity
|
GO:0090073 |
1 |
0.010
|
|
|
neuron death
|
GO:0070997 |
154 |
0.010
|
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.010
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
61 |
0.010
|
|
|
positive regulation of camp mediated signaling
|
GO:0043950 |
3 |
0.010
|
|
|
response to starvation
|
GO:0042594 |
65 |
0.010
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.010
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.010
|
|
|
superoxide metabolic process
|
GO:0006801 |
27 |
0.010
|
|