Mus musculus

20 known processes

Hsd17b12

hydroxysteroid (17-beta) dehydrogenase 12

(Aliases: AI172963,KIK-I,2610510O05Rik,Kik1)

Hsd17b12 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular alcohol biosynthetic process GO:0044108 3 0.339
lipid biosynthetic process GO:0008610 179 0.313
Yeast Worm
organic hydroxy compound metabolic process GO:1901615 203 0.221
oxidation reduction process GO:0055114 342 0.176
Yeast Worm
membrane lipid biosynthetic process GO:0046467 32 0.154
Yeast
cellular lipid metabolic process GO:0044255 323 0.140
Yeast Worm
alcohol biosynthetic process GO:0046165 43 0.135
transmembrane transport GO:0055085 412 0.104
organophosphate biosynthetic process GO:0090407 122 0.099
carbohydrate derivative biosynthetic process GO:1901137 183 0.096
sphingolipid biosynthetic process GO:0030148 26 0.094
Yeast
sterol metabolic process GO:0016125 58 0.082
organic hydroxy compound biosynthetic process GO:1901617 77 0.081
anion transport GO:0006820 177 0.080
cellular homeostasis GO:0019725 240 0.079
ribose phosphate biosynthetic process GO:0046390 59 0.078
organic anion transport GO:0015711 137 0.076
regulation of apoptotic signaling pathway GO:2001233 197 0.073
ion transmembrane transport GO:0034220 361 0.073
cellular chemical homeostasis GO:0055082 215 0.072
organic acid transport GO:0015849 101 0.068
alcohol metabolic process GO:0006066 116 0.068
cellular alcohol metabolic process GO:0044107 3 0.057
intracellular protein transport GO:0006886 204 0.057
positive regulation of apoptotic process GO:0043065 217 0.057
cellular metal ion homeostasis GO:0006875 151 0.056
cation transport GO:0006812 399 0.055
endocytosis GO:0006897 168 0.054
positive regulation of cell death GO:0010942 224 0.049
cofactor transport GO:0051181 4 0.049
ribonucleoside metabolic process GO:0009119 245 0.049
response to organonitrogen compound GO:0010243 246 0.047
cellular calcium ion homeostasis GO:0006874 119 0.046
positive regulation of programmed cell death GO:0043068 218 0.046
cytoplasmic transport GO:0016482 234 0.046
monocarboxylic acid metabolic process GO:0032787 191 0.045
Yeast Worm
dna metabolic process GO:0006259 303 0.044
engulfment of apoptotic cell GO:0043652 3 0.040
lipid localization GO:0010876 126 0.040
nucleobase containing small molecule metabolic process GO:0055086 352 0.040
calcium ion homeostasis GO:0055074 127 0.039
fatty acid metabolic process GO:0006631 121 0.039
Yeast Worm
small molecule biosynthetic process GO:0044283 132 0.039
Yeast Worm
carbohydrate metabolic process GO:0005975 230 0.038
divalent inorganic cation homeostasis GO:0072507 138 0.037
nadph regeneration GO:0006740 2 0.035
regulation of cellular amine metabolic process GO:0033238 20 0.035
sphingolipid metabolic process GO:0006665 45 0.034
Yeast
cellular nitrogen compound catabolic process GO:0044270 280 0.034
amine metabolic process GO:0009308 45 0.034
sterol biosynthetic process GO:0016126 17 0.034
organonitrogen compound biosynthetic process GO:1901566 192 0.033
Yeast
protein targeting GO:0006605 143 0.033
cellular ion homeostasis GO:0006873 165 0.033
cellular amino acid metabolic process GO:0006520 103 0.033
ribonucleotide biosynthetic process GO:0009260 59 0.033
negative regulation of cellular component organization GO:0051129 194 0.032
positive regulation of growth GO:0045927 104 0.032
male anatomical structure morphogenesis GO:0090598 4 0.032
ribonucleotide metabolic process GO:0009259 291 0.032
protein catabolic process GO:0030163 221 0.031
lipid transport GO:0006869 98 0.031
cation homeostasis GO:0055080 212 0.031
positive regulation of apoptotic signaling pathway GO:2001235 95 0.031
nitrogen compound transport GO:0071705 271 0.031
metal ion homeostasis GO:0055065 189 0.030
purine ribonucleoside metabolic process GO:0046128 241 0.030
regulation of secretion GO:0051046 274 0.030
carboxylic acid transport GO:0046942 100 0.030
regulation of lipid metabolic process GO:0019216 118 0.029
nucleotide biosynthetic process GO:0009165 78 0.028
cellular amine metabolic process GO:0044106 44 0.028
regulation of mitochondrion organization GO:0010821 27 0.028
regulation of membrane potential GO:0042391 192 0.027
steroid biosynthetic process GO:0006694 47 0.027
Worm
response to organic cyclic compound GO:0014070 198 0.027
cellular biogenic amine metabolic process GO:0006576 28 0.026
establishment of organelle localization GO:0051656 122 0.026
myeloid cell differentiation GO:0030099 233 0.026
mitochondrion distribution GO:0048311 4 0.025
cellular ketone metabolic process GO:0042180 84 0.025
purine ribonucleotide biosynthetic process GO:0009152 59 0.025
regulation of hormone levels GO:0010817 211 0.025
Worm
glycerolipid metabolic process GO:0046486 122 0.025
insulin secretion GO:0030073 89 0.025
ribonucleoside catabolic process GO:0042454 206 0.024
methylation GO:0032259 134 0.024
apoptotic signaling pathway GO:0097190 306 0.024
synaptic vesicle transport GO:0048489 57 0.024
synaptic transmission GO:0007268 329 0.024
regulation of cellular ketone metabolic process GO:0010565 66 0.024
steroid metabolic process GO:0008202 119 0.024
Worm
purine nucleotide biosynthetic process GO:0006164 65 0.023
purine nucleoside metabolic process GO:0042278 241 0.023
mitochondrial calcium ion homeostasis GO:0051560 7 0.023
regulation of ion transport GO:0043269 215 0.022
multi organism behavior GO:0051705 62 0.022
inorganic ion transmembrane transport GO:0098660 234 0.022
cytosolic calcium ion homeostasis GO:0051480 70 0.022
inorganic cation transmembrane transport GO:0098662 207 0.022
response to nutrient levels GO:0031667 109 0.022
nucleoside biosynthetic process GO:0009163 21 0.022
nucleoside phosphate metabolic process GO:0006753 338 0.021
action potential GO:0001508 78 0.021
response to unfolded protein GO:0006986 21 0.021
regulation of secretion by cell GO:1903530 249 0.021
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.021
protein localization to organelle GO:0033365 185 0.021
protein refolding GO:0042026 1 0.021
purine ribonucleotide metabolic process GO:0009150 290 0.021
membrane organization GO:0061024 245 0.021
positive regulation of cellular amine metabolic process GO:0033240 5 0.021
peptide hormone secretion GO:0030072 109 0.021
mitochondrion organization GO:0007005 134 0.021
sensory organ morphogenesis GO:0090596 242 0.021
carbohydrate derivative catabolic process GO:1901136 231 0.020
establishment of vesicle localization GO:0051650 81 0.020
ribose phosphate metabolic process GO:0019693 291 0.020
monocarboxylic acid transport GO:0015718 44 0.020
establishment of synaptic vesicle localization GO:0097480 57 0.020
nucleoside phosphate biosynthetic process GO:1901293 79 0.020
amide transport GO:0042886 138 0.020
ribonucleoside triphosphate metabolic process GO:0009199 220 0.020
positive regulation of secretion by cell GO:1903532 114 0.020
regulation of peptide transport GO:0090087 91 0.020
cellular response to lipid GO:0071396 145 0.019
regulation of cellular component biogenesis GO:0044087 181 0.019
organelle localization GO:0051640 179 0.019
multi multicellular organism process GO:0044706 109 0.019
blood vessel morphogenesis GO:0048514 285 0.019
purine ribonucleoside biosynthetic process GO:0046129 19 0.019
cellularization GO:0007349 1 0.019
synaptic vesicle localization GO:0097479 59 0.019
fatty acid elongation GO:0030497 3 0.019
Yeast
multicellular organism growth GO:0035264 161 0.019
purine nucleoside biosynthetic process GO:0042451 19 0.019
positive regulation of growth hormone secretion GO:0060124 3 0.019
nucleotide metabolic process GO:0009117 332 0.019
purine containing compound metabolic process GO:0072521 311 0.019
cellular divalent inorganic cation homeostasis GO:0072503 127 0.018
peptide transport GO:0015833 133 0.018
extracellular matrix organization GO:0030198 147 0.018
regulation of homeostatic process GO:0032844 182 0.018
regulation of anatomical structure size GO:0090066 178 0.018
protein import GO:0017038 101 0.017
organism emergence from protective structure GO:0071684 4 0.017
ribonucleoside monophosphate metabolic process GO:0009161 80 0.017
cellular response to hormone stimulus GO:0032870 150 0.017
glucose metabolic process GO:0006006 92 0.017
nucleoside metabolic process GO:0009116 246 0.017
vesicle localization GO:0051648 86 0.017
ribonucleoside biosynthetic process GO:0042455 21 0.016
cellular amino acid catabolic process GO:0009063 25 0.016
membrane lipid metabolic process GO:0006643 53 0.016
Yeast
regulation of cellular amino acid metabolic process GO:0006521 5 0.016
cation transmembrane transport GO:0098655 266 0.016
regulation of protein localization GO:0032880 231 0.016
interleukin 8 secretion GO:0072606 3 0.016
carboxylic acid catabolic process GO:0046395 51 0.016
nuclear transport GO:0051169 139 0.016
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.016
glucose catabolic process GO:0006007 3 0.016
nucleoside triphosphate catabolic process GO:0009143 205 0.016
skeletal system development GO:0001501 356 0.016
regulation of intracellular transport GO:0032386 159 0.016
homeostasis of number of cells GO:0048872 210 0.016
fatty acid transmembrane transport GO:1902001 1 0.016
endoplasmic reticulum unfolded protein response GO:0030968 19 0.015
regulation of system process GO:0044057 200 0.015
camera type eye development GO:0043010 266 0.015
actin filament polymerization GO:0030041 44 0.015
regulation of phospholipid biosynthetic process GO:0071071 3 0.015
phospholipid metabolic process GO:0006644 87 0.015
positive regulation of secretion GO:0051047 130 0.015
nucleoside phosphate catabolic process GO:1901292 222 0.015
extrinsic apoptotic signaling pathway GO:0097191 126 0.015
positive regulation of cell development GO:0010720 237 0.015
hormone secretion GO:0046879 128 0.015
purine nucleoside monophosphate metabolic process GO:0009126 81 0.015
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.015
locomotory behavior GO:0007626 195 0.015
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.015
mapk cascade GO:0000165 281 0.015
regulation of phosphatidylcholine biosynthetic process GO:2001245 2 0.015
pigment biosynthetic process GO:0046148 26 0.015
protein oligomerization GO:0051259 67 0.015
cellular carbohydrate metabolic process GO:0044262 119 0.015
pentose phosphate shunt GO:0006098 2 0.015
hatching GO:0035188 4 0.015
establishment of protein localization to organelle GO:0072594 118 0.015
transmission of nerve impulse GO:0019226 76 0.014
protein tetramerization GO:0051262 23 0.014
response to topologically incorrect protein GO:0035966 25 0.014
nucleoside triphosphate metabolic process GO:0009141 230 0.014
purine nucleoside catabolic process GO:0006152 205 0.014
sensory perception GO:0007600 245 0.014
leukocyte proliferation GO:0070661 172 0.014
peptide secretion GO:0002790 114 0.014
asymmetric stem cell division GO:0098722 3 0.014
cellular component assembly involved in morphogenesis GO:0010927 139 0.014
multicellular organismal signaling GO:0035637 91 0.014
maintenance of location GO:0051235 89 0.014
multicellular organismal aging GO:0010259 24 0.014
Worm
long chain fatty acid metabolic process GO:0001676 26 0.014
Worm
nucleobase containing compound transport GO:0015931 27 0.014
pyridine nucleotide biosynthetic process GO:0019363 4 0.014
regionalization GO:0003002 337 0.014
hexose catabolic process GO:0019320 3 0.014
phosphatidylethanolamine metabolic process GO:0046337 2 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.014
regulation of organelle organization GO:0033043 289 0.014
response to acid chemical GO:0001101 111 0.013
response to extracellular stimulus GO:0009991 127 0.013
protein import into nucleus GO:0006606 95 0.013
nucleoside monophosphate metabolic process GO:0009123 85 0.013
glycosyl compound metabolic process GO:1901657 246 0.013
t cell activation GO:0042110 289 0.013
er nucleus signaling pathway GO:0006984 27 0.013
stem cell differentiation GO:0048863 268 0.013
carbohydrate homeostasis GO:0033500 128 0.013
ras protein signal transduction GO:0007265 77 0.013
regulation of translation GO:0006417 71 0.013
positive regulation of endopeptidase activity GO:0010950 43 0.013
telencephalon development GO:0021537 186 0.013
negative regulation of molecular function GO:0044092 258 0.013
neuron apoptotic process GO:0051402 142 0.013
endomembrane system organization GO:0010256 147 0.013
sequestering of metal ion GO:0051238 19 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.012
divalent inorganic cation transport GO:0072511 178 0.012
glucose homeostasis GO:0042593 128 0.012
forebrain development GO:0030900 302 0.012
cellular response to organonitrogen compound GO:0071417 145 0.012
muscle cell differentiation GO:0042692 261 0.012
microtubule based process GO:0007017 236 0.012
nucleocytoplasmic transport GO:0006913 139 0.012
hypotonic response GO:0006971 3 0.012
organelle disassembly GO:1903008 2 0.012
monosaccharide metabolic process GO:0005996 106 0.012
divalent metal ion transport GO:0070838 172 0.012
regulation of cell growth GO:0001558 91 0.012
angiogenesis GO:0001525 201 0.012
acylglycerol metabolic process GO:0006639 55 0.011
activation of adenylate cyclase activity GO:0007190 4 0.011
endoplasmic reticulum tubular network organization GO:0071786 1 0.011
receptor mediated endocytosis GO:0006898 51 0.011
fatty acid elongation unsaturated fatty acid GO:0019368 2 0.011
spermatogenesis GO:0007283 284 0.011
regulation of peptide secretion GO:0002791 77 0.011
purine containing compound biosynthetic process GO:0072522 70 0.011
translation GO:0006412 93 0.011
glycosyl compound biosynthetic process GO:1901659 21 0.011
regulation of endopeptidase activity GO:0052548 89 0.011
asymmetric neuroblast division GO:0055059 1 0.011
extracellular structure organization GO:0043062 148 0.011
small gtpase mediated signal transduction GO:0007264 97 0.011
regulation of cell cycle GO:0051726 281 0.011
cellular modified amino acid metabolic process GO:0006575 63 0.011
regulation of peptide hormone secretion GO:0090276 75 0.011
negative regulation of multi organism process GO:0043901 68 0.011
organophosphate catabolic process GO:0046434 232 0.011
organic cyclic compound catabolic process GO:1901361 295 0.011
positive regulation of protein transport GO:0051222 93 0.011
monocarboxylic acid biosynthetic process GO:0072330 61 0.011
Yeast Worm
protein localization to membrane GO:0072657 108 0.011
fatty acid transport GO:0015908 28 0.011
purine nucleotide metabolic process GO:0006163 302 0.011
cellular response to organic cyclic compound GO:0071407 87 0.011
macromolecule methylation GO:0043414 120 0.011
calcium ion transport GO:0006816 159 0.010
positive regulation of fatty acid oxidation GO:0046321 4 0.010
interleukin 8 production GO:0032637 4 0.010
exocytosis GO:0006887 121 0.010
positive regulation of organelle organization GO:0010638 128 0.010
triglyceride biosynthetic process GO:0019432 17 0.010
axonogenesis GO:0007409 274 0.010
blood circulation GO:0008015 195 0.010
aromatic compound catabolic process GO:0019439 286 0.010
regulation of transmembrane transport GO:0034762 128 0.010
regulation of vesicle mediated transport GO:0060627 139 0.010
amp metabolic process GO:0046033 4 0.010
muscle system process GO:0003012 141 0.010
organic acid catabolic process GO:0016054 51 0.010
negative regulation of protein metabolic process GO:0051248 282 0.010
actin polymerization or depolymerization GO:0008154 54 0.010
dephosphorylation GO:0016311 129 0.010
heterocycle catabolic process GO:0046700 280 0.010
regulation of mapk cascade GO:0043408 248 0.010

Hsd17b12 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.057
inherited metabolic disorder DOID:655 0 0.057
disease of anatomical entity DOID:7 0 0.021
nervous system disease DOID:863 0 0.021
carbohydrate metabolic disorder DOID:2978 0 0.014
neuropathy DOID:870 0 0.011