Mus musculus

7 known processes

Hsd3b4

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 4

Hsd3b4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
saturated monocarboxylic acid metabolic process GO:0032788 2 0.907
fatty acid metabolic process GO:0006631 121 0.868
amino acid betaine transport GO:0015838 3 0.826
response to stilbenoid GO:0035634 22 0.813
carnitine transmembrane transport GO:1902603 3 0.796
carnitine transport GO:0015879 3 0.740
monocarboxylic acid metabolic process GO:0032787 191 0.695
short chain fatty acid metabolic process GO:0046459 6 0.609
cellular lipid metabolic process GO:0044255 323 0.603
ion transmembrane transport GO:0034220 361 0.568
response to phenylpropanoid GO:0080184 22 0.556
membrane organization GO:0061024 245 0.550
carboxylic acid catabolic process GO:0046395 51 0.521
steroid metabolic process GO:0008202 119 0.521
Human Rat
amino acid transmembrane transport GO:0003333 37 0.513
regulation of blood pressure GO:0008217 93 0.505
glutathione metabolic process GO:0006749 16 0.502
cellular amino acid metabolic process GO:0006520 103 0.392
hormone metabolic process GO:0042445 86 0.362
Rat
amino acid betaine metabolic process GO:0006577 7 0.348
sulfur compound metabolic process GO:0006790 100 0.305
monovalent inorganic cation homeostasis GO:0055067 33 0.297
organic hydroxy compound metabolic process GO:1901615 203 0.297
monocyte chemotactic protein 1 production GO:0071605 1 0.284
oxidation reduction process GO:0055114 342 0.275
Human Rat
cofactor metabolic process GO:0051186 80 0.252
plasma membrane organization GO:0007009 90 0.241
coenzyme metabolic process GO:0006732 52 0.225
modified amino acid transport GO:0072337 5 0.224
renal system process GO:0003014 48 0.213
potassium ion transmembrane transport GO:0071805 43 0.203
carboxylic acid biosynthetic process GO:0046394 86 0.196
hydrogen ion transmembrane transport GO:1902600 25 0.195
thioester metabolic process GO:0035383 19 0.179
cellular amide metabolic process GO:0043603 58 0.172
organic acid catabolic process GO:0016054 51 0.171
vasoconstriction GO:0042310 27 0.169
inorganic ion transmembrane transport GO:0098660 234 0.158
lipid biosynthetic process GO:0008610 179 0.155
Human Rat
transmembrane transport GO:0055085 412 0.150
regulation of body fluid levels GO:0050878 162 0.148
renal system development GO:0072001 225 0.132
protein processing GO:0016485 163 0.124
endomembrane system organization GO:0010256 147 0.117
cation transmembrane transport GO:0098655 266 0.116
proton transport GO:0015992 35 0.113
amine metabolic process GO:0009308 45 0.111
cellular modified amino acid metabolic process GO:0006575 63 0.111
inorganic anion transport GO:0015698 43 0.111
cellular homeostasis GO:0019725 240 0.106
cellular carbohydrate metabolic process GO:0044262 119 0.104
regulation of ph GO:0006885 26 0.102
folic acid containing compound metabolic process GO:0006760 3 0.102
protein maturation GO:0051604 176 0.098
succinyl coa metabolic process GO:0006104 1 0.096
lipid transport GO:0006869 98 0.096
dicarboxylic acid metabolic process GO:0043648 18 0.094
regulation of chloride transport GO:2001225 2 0.094
small molecule catabolic process GO:0044282 71 0.093
potassium ion homeostasis GO:0055075 4 0.092
peptide metabolic process GO:0006518 46 0.091
regulation of hormone levels GO:0010817 211 0.091
Rat
regulation of blood vessel size GO:0050880 56 0.091
unsaturated fatty acid metabolic process GO:0033559 31 0.088
cation homeostasis GO:0055080 212 0.087
sterol homeostasis GO:0055092 45 0.086
long chain fatty acid metabolic process GO:0001676 26 0.085
ribonucleoside metabolic process GO:0009119 245 0.083
cellular potassium ion transport GO:0071804 43 0.083
hydrogen transport GO:0006818 35 0.082
glycolytic process GO:0006096 20 0.082
negative regulation of molecular function GO:0044092 258 0.078
regulation of neurotransmitter levels GO:0001505 87 0.075
pyruvate metabolic process GO:0006090 28 0.075
organic cyclic compound catabolic process GO:1901361 295 0.075
organic anion transport GO:0015711 137 0.074
organic acid transport GO:0015849 101 0.071
cellular ion homeostasis GO:0006873 165 0.070
alpha amino acid metabolic process GO:1901605 59 0.070
anion transmembrane transport GO:0098656 71 0.069
small molecule biosynthetic process GO:0044283 132 0.069
progesterone metabolic process GO:0042448 4 0.068
Rat
kidney development GO:0001822 213 0.068
alcohol metabolic process GO:0006066 116 0.067
purine containing compound metabolic process GO:0072521 311 0.065
organic hydroxy compound transport GO:0015850 93 0.064
regulation of tube size GO:0035150 57 0.063
nucleoside metabolic process GO:0009116 246 0.062
nucleoside triphosphate metabolic process GO:0009141 230 0.061
regulation of cellular amine metabolic process GO:0033238 20 0.060
cell junction organization GO:0034330 77 0.060
anion transport GO:0006820 177 0.060
carnitine metabolic process GO:0009437 7 0.059
cell matrix adhesion GO:0007160 68 0.058
cellular amine metabolic process GO:0044106 44 0.058
cation transport GO:0006812 399 0.057
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.057
response to nutrient levels GO:0031667 109 0.056
regulation of lipid transport GO:0032368 36 0.055
generation of precursor metabolites and energy GO:0006091 103 0.055
9 cis retinoic acid metabolic process GO:0042905 5 0.055
response to organic cyclic compound GO:0014070 198 0.055
wound healing GO:0042060 157 0.053
urate transport GO:0015747 1 0.053
epidermis development GO:0008544 187 0.053
nucleoside monophosphate metabolic process GO:0009123 85 0.053
urogenital system development GO:0001655 261 0.051
atp metabolic process GO:0046034 75 0.050
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.050
regulation of renal sodium excretion GO:0035813 3 0.050
organic acid biosynthetic process GO:0016053 86 0.048
atp catabolic process GO:0006200 55 0.048
organonitrogen compound catabolic process GO:1901565 264 0.047
organophosphate catabolic process GO:0046434 232 0.046
cell adhesion GO:0007155 329 0.046
cellular response to lipid GO:0071396 145 0.045
organic hydroxy compound catabolic process GO:1901616 25 0.045
purine ribonucleoside metabolic process GO:0046128 241 0.044
circulatory system process GO:0003013 197 0.044
icosanoid metabolic process GO:0006690 33 0.044
cell substrate adhesion GO:0031589 130 0.043
skin development GO:0043588 220 0.042
tetrapyrrole metabolic process GO:0033013 22 0.042
regulation of kinase activity GO:0043549 249 0.042
fatty acid biosynthetic process GO:0006633 41 0.042
regulation of secretion GO:0051046 274 0.040
regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 33 0.040
protein localization to membrane GO:0072657 108 0.040
histamine uptake GO:0051615 1 0.039
carbohydrate catabolic process GO:0016052 32 0.038
potassium ion transport GO:0006813 52 0.038
negative regulation of peroxidase activity GO:2000469 1 0.037
positive regulation of lipid transport GO:0032370 22 0.037
multicellular organism growth GO:0035264 161 0.037
cellular response to hormone stimulus GO:0032870 150 0.036
protein targeting to membrane GO:0006612 20 0.036
ribonucleotide metabolic process GO:0009259 291 0.036
excretion GO:0007588 22 0.036
monocarboxylic acid biosynthetic process GO:0072330 61 0.036
glycosyl compound metabolic process GO:1901657 246 0.036
lipid localization GO:0010876 126 0.036
purine ribonucleotide metabolic process GO:0009150 290 0.035
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.035
carboxylic acid transport GO:0046942 100 0.035
muscle cell differentiation GO:0042692 261 0.034
inflammatory response GO:0006954 244 0.033
purine nucleoside metabolic process GO:0042278 241 0.033
nucleobase containing small molecule metabolic process GO:0055086 352 0.033
nucleoside monophosphate catabolic process GO:0009125 59 0.033
protein localization to plasma membrane GO:0072659 57 0.032
metal ion homeostasis GO:0055065 189 0.032
c21 steroid hormone biosynthetic process GO:0006700 3 0.032
nucleoside phosphate catabolic process GO:1901292 222 0.032
monocarboxylic acid catabolic process GO:0072329 27 0.031
spermatogenesis GO:0007283 284 0.031
regulation of carbohydrate metabolic process GO:0006109 75 0.031
response to steroid hormone GO:0048545 56 0.031
regulation of establishment of protein localization GO:0070201 181 0.030
cell cell junction organization GO:0045216 72 0.030
renal tubular secretion GO:0097254 2 0.030
blood circulation GO:0008015 195 0.030
response to oxidative stress GO:0006979 123 0.029
sodium ion transport GO:0006814 73 0.029
regulation of mapk cascade GO:0043408 248 0.029
negative regulation of nitric oxide synthase biosynthetic process GO:0051771 1 0.029
regulation of systemic arterial blood pressure by hormone GO:0001990 25 0.029
chloride transport GO:0006821 32 0.029
negative regulation of protein modification process GO:0031400 163 0.028
vascular process in circulatory system GO:0003018 62 0.028
methionine transport GO:0015821 1 0.027
regulation of anatomical structure size GO:0090066 178 0.027
purine nucleotide metabolic process GO:0006163 302 0.027
cellular response to hepatocyte growth factor stimulus GO:0035729 2 0.027
purine containing compound catabolic process GO:0072523 213 0.026
inorganic anion transmembrane transport GO:0098661 29 0.026
ovulation GO:0030728 15 0.026
response to peptide hormone GO:0043434 127 0.026
regulation of glucose metabolic process GO:0010906 60 0.026
ribose phosphate metabolic process GO:0019693 291 0.026
acyl coa metabolic process GO:0006637 19 0.026
purine nucleoside monophosphate metabolic process GO:0009126 81 0.026
cellular response to organonitrogen compound GO:0071417 145 0.025
positive regulation of cellular amine metabolic process GO:0033240 5 0.025
interspecies interaction between organisms GO:0044419 83 0.025
blood vessel morphogenesis GO:0048514 285 0.025
diterpenoid biosynthetic process GO:0016102 7 0.025
negative regulation of monocyte chemotactic protein 1 production GO:0071638 1 0.025
cellular amino acid catabolic process GO:0009063 25 0.025
regulation of membrane potential GO:0042391 192 0.024
protein localization to organelle GO:0033365 185 0.024
purine nucleoside triphosphate catabolic process GO:0009146 203 0.024
intracellular protein transport GO:0006886 204 0.024
positive regulation of wnt signaling pathway GO:0030177 45 0.024
very long chain fatty acid metabolic process GO:0000038 8 0.023
nucleoside triphosphate catabolic process GO:0009143 205 0.023
regulation of protein kinase activity GO:0045859 232 0.023
neurotransmitter uptake GO:0001504 14 0.023
purine nucleoside monophosphate catabolic process GO:0009128 58 0.023
determination of adult lifespan GO:0008340 11 0.023
neurotransmitter transport GO:0006836 76 0.023
carbohydrate biosynthetic process GO:0016051 74 0.023
regulation of transferase activity GO:0051338 263 0.022
fatty acid derivative metabolic process GO:1901568 33 0.022
response to growth factor GO:0070848 198 0.022
sensory organ morphogenesis GO:0090596 242 0.022
reactive oxygen species metabolic process GO:0072593 84 0.022
ribonucleoside triphosphate metabolic process GO:0009199 220 0.022
cellular response to peptide hormone stimulus GO:0071375 92 0.022
chloride transmembrane transport GO:1902476 24 0.021
locomotory behavior GO:0007626 195 0.021
regulation of protein serine threonine kinase activity GO:0071900 157 0.021
regulation of systemic arterial blood pressure by renin angiotensin GO:0003081 20 0.021
regulation of anion transport GO:0044070 27 0.021
purine ribonucleoside catabolic process GO:0046130 205 0.021
regulation of cellular ketone metabolic process GO:0010565 66 0.021
ribonucleoside monophosphate metabolic process GO:0009161 80 0.020
ribonucleoside monophosphate catabolic process GO:0009158 57 0.020
regulation of ion transport GO:0043269 215 0.020
response to osmotic stress GO:0006970 21 0.020
cellular response to growth factor stimulus GO:0071363 197 0.020
inorganic cation transmembrane transport GO:0098662 207 0.020
glucocorticoid metabolic process GO:0008211 9 0.020
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.020
regulation of inflammatory response GO:0050727 147 0.019
neuronal action potential GO:0019228 54 0.019
cellular response to lipopolysaccharide GO:0071222 77 0.019
gluconeogenesis GO:0006094 39 0.019
negative regulation of intracellular signal transduction GO:1902532 167 0.019
endocytosis GO:0006897 168 0.019
carbohydrate metabolic process GO:0005975 230 0.019
monocarboxylic acid transport GO:0015718 44 0.019
oligopeptide transmembrane transport GO:0035672 4 0.019
d amino acid transport GO:0042940 1 0.019
one carbon metabolic process GO:0006730 1 0.019
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.019
dephosphorylation GO:0016311 129 0.019
cellular amino acid biosynthetic process GO:0008652 22 0.019
mapk cascade GO:0000165 281 0.018
purine ribonucleotide biosynthetic process GO:0009152 59 0.018
establishment of protein localization to membrane GO:0090150 54 0.018
cellular response to peptide GO:1901653 92 0.018
cellular chemical homeostasis GO:0055082 215 0.018
midgut development GO:0007494 4 0.018
regulation of system process GO:0044057 200 0.018
response to drug GO:0042493 75 0.018
response to organonitrogen compound GO:0010243 246 0.018
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.018
regulation of protein processing GO:0070613 96 0.018
organonitrogen compound biosynthetic process GO:1901566 192 0.017
regulation of lipid biosynthetic process GO:0046890 54 0.017
Rat
cell junction assembly GO:0034329 52 0.017
macromolecule catabolic process GO:0009057 281 0.017
cellular lipid catabolic process GO:0044242 52 0.017
response to acid chemical GO:0001101 111 0.017
nucleotide catabolic process GO:0009166 217 0.017
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.017
multicellular organismal signaling GO:0035637 91 0.017
anatomical structure homeostasis GO:0060249 145 0.017
response to temperature stimulus GO:0009266 55 0.016
adult locomotory behavior GO:0008344 91 0.016
regulation of serine type endopeptidase activity GO:1900003 2 0.016
dipeptide transport GO:0042938 2 0.016
establishment of protein localization to organelle GO:0072594 118 0.016
short chain fatty acid catabolic process GO:0019626 2 0.016
fatty acid transport GO:0015908 28 0.016
male gamete generation GO:0048232 285 0.016
ribonucleoside catabolic process GO:0042454 206 0.015
monoamine transport GO:0015844 33 0.015
multicellular organismal homeostasis GO:0048871 164 0.015
porphyrin containing compound metabolic process GO:0006778 22 0.015
establishment of vesicle localization GO:0051650 81 0.015
toxin transport GO:1901998 38 0.015
iron ion homeostasis GO:0055072 36 0.015
memory GO:0007613 58 0.015
multicellular organismal water homeostasis GO:0050891 23 0.015
transition metal ion homeostasis GO:0055076 54 0.015
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.015
fatty acid oxidation GO:0019395 28 0.015
regulation of receptor activity GO:0010469 41 0.015
aromatic compound catabolic process GO:0019439 286 0.015
negative regulation of nervous system development GO:0051961 156 0.015
nitrogen compound transport GO:0071705 271 0.015
monosaccharide biosynthetic process GO:0046364 44 0.015
dopamine uptake GO:0090494 4 0.014
response to hepatocyte growth factor GO:0035728 2 0.014
protein targeting GO:0006605 143 0.014
regulation of protein kinase c activity GO:1900019 1 0.014
lipid modification GO:0030258 65 0.014
gonad development GO:0008406 141 0.014
mesonephric epithelium development GO:0072163 94 0.014
regulation of gluconeogenesis GO:0006111 30 0.014
muscle contraction GO:0006936 101 0.014
response to insulin GO:0032868 100 0.014
negative regulation of muscle contraction GO:0045932 12 0.013
negative regulation of cellular protein metabolic process GO:0032269 247 0.013
kidney epithelium development GO:0072073 121 0.013
neutral lipid metabolic process GO:0006638 57 0.013
protein tetramerization GO:0051262 23 0.013
regulation of endopeptidase activity GO:0052548 89 0.013
renal system process involved in regulation of blood volume GO:0001977 4 0.013
regulation of renal output by angiotensin GO:0002019 2 0.013
benzene containing compound metabolic process GO:0042537 5 0.013
positive regulation of hormone secretion GO:0046887 38 0.013
multicellular organismal aging GO:0010259 24 0.013
regulation of cellular amino acid metabolic process GO:0006521 5 0.013
fibrinolysis GO:0042730 3 0.013
nucleotide metabolic process GO:0009117 332 0.013
meiotic cell cycle process GO:1903046 77 0.013
response to estrogen GO:0043627 24 0.013
response to corticosterone GO:0051412 1 0.013
spermatid differentiation GO:0048515 115 0.012
positive regulation of dopamine uptake involved in synaptic transmission GO:0051586 2 0.012
actomyosin structure organization GO:0031032 56 0.012
purine nucleotide catabolic process GO:0006195 211 0.012
negative regulation of cell proliferation GO:0008285 296 0.012
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 4 0.012
cellular response to cadmium ion GO:0071276 3 0.012
female gamete generation GO:0007292 74 0.012
cellular response to acid chemical GO:0071229 68 0.012
renin angiotensin regulation of aldosterone production GO:0002018 3 0.012
positive regulation of steroid hormone secretion GO:2000833 2 0.012
regulation of hydrolase activity GO:0051336 246 0.012
single organism cell adhesion GO:0098602 156 0.012
establishment of organelle localization GO:0051656 122 0.012
cellular response to molecule of bacterial origin GO:0071219 83 0.011
glial cell development GO:0021782 54 0.011
catecholamine uptake GO:0090493 4 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.011
purine ribonucleotide catabolic process GO:0009154 208 0.011
amide transport GO:0042886 138 0.011
glucan metabolic process GO:0044042 32 0.011
negative regulation of protein maturation GO:1903318 79 0.011
renal sodium ion transport GO:0003096 2 0.011
fatty acid catabolic process GO:0009062 25 0.011
histamine transport GO:0051608 2 0.011
c21 steroid hormone metabolic process GO:0008207 7 0.011
Rat
cellular response to prostaglandin stimulus GO:0071379 2 0.011
regulation of binding GO:0051098 111 0.011
brain renin angiotensin system GO:0002035 5 0.011
brown fat cell differentiation GO:0050873 36 0.011
response to metal ion GO:0010038 47 0.011
carbohydrate derivative biosynthetic process GO:1901137 183 0.011
ribonucleoside triphosphate catabolic process GO:0009203 199 0.011
d serine transport GO:0042942 1 0.011
protein catabolic process GO:0030163 221 0.011
ear development GO:0043583 200 0.011
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.011
cell cell adhesion GO:0098609 41 0.011
cellular polysaccharide metabolic process GO:0044264 38 0.011
receptor mediated endocytosis GO:0006898 51 0.011
mitotic cell cycle process GO:1903047 159 0.010
mitotic cell cycle GO:0000278 195 0.010
renal system process involved in regulation of systemic arterial blood pressure GO:0003071 15 0.010
nucleoside phosphate metabolic process GO:0006753 338 0.010
response to inorganic substance GO:0010035 96 0.010
response to monosaccharide GO:0034284 67 0.010
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.010
superoxide anion generation GO:0042554 11 0.010
cellular response to insulin stimulus GO:0032869 78 0.010
nuclear import GO:0051170 95 0.010

Hsd3b4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.159
disease of anatomical entity DOID:7 0 0.159
hematopoietic system disease DOID:74 0 0.159
disease of metabolism DOID:0014667 0 0.159
Human
inherited metabolic disorder DOID:655 0 0.159
Human
anemia DOID:2355 0 0.106
normocytic anemia DOID:720 0 0.073
lipid metabolism disorder DOID:3146 0 0.023
Human
steroid inherited metabolic disorder DOID:1701 0 0.023
Human