|
|
protein refolding
|
GO:0042026 |
1 |
1.000
|
Yeast |
|
|
protein targeting to mitochondrion
|
GO:0006626 |
6 |
0.995
|
Yeast |
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.994
|
Fly |
|
|
organelle assembly
|
GO:0070925 |
177 |
0.993
|
Zebrafish |
|
|
microtubule based process
|
GO:0007017 |
236 |
0.986
|
Fly |
|
|
protein transmembrane transport
|
GO:0071806 |
8 |
0.982
|
|
|
|
negative regulation of transposition
|
GO:0010529 |
2 |
0.914
|
Fly |
|
|
sperm egg recognition
|
GO:0035036 |
37 |
0.910
|
|
|
|
centrosome cycle
|
GO:0007098 |
23 |
0.901
|
Fly |
|
|
de novo protein folding
|
GO:0006458 |
9 |
0.891
|
Yeast |
|
|
protein folding
|
GO:0006457 |
28 |
0.859
|
Yeast |
|
|
chaperone mediated protein folding
|
GO:0061077 |
10 |
0.848
|
|
|
|
vesicle uncoating
|
GO:0072319 |
4 |
0.768
|
|
|
|
response to heat
|
GO:0009408 |
27 |
0.759
|
Yeast Rat Fly |
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.749
|
Yeast Rat |
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.747
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.746
|
|
|
|
cell cell recognition
|
GO:0009988 |
44 |
0.719
|
|
|
|
binding of sperm to zona pellucida
|
GO:0007339 |
34 |
0.681
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.628
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.624
|
Yeast Zebrafish |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.613
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.611
|
Yeast Rat |
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.610
|
|
|
|
microtubule organizing center organization
|
GO:0031023 |
28 |
0.602
|
Fly |
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.601
|
Yeast |
|
|
protein import into nucleus translocation
|
GO:0000060 |
12 |
0.556
|
Rat |
|
|
atp catabolic process
|
GO:0006200 |
55 |
0.548
|
Yeast Worm |
|
|
organelle disassembly
|
GO:1903008 |
2 |
0.537
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.536
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.534
|
Yeast Worm |
|
|
centrosome organization
|
GO:0051297 |
26 |
0.532
|
Fly |
|
|
rna processing
|
GO:0006396 |
105 |
0.528
|
|
|
|
ribonucleoprotein complex disassembly
|
GO:0032988 |
3 |
0.527
|
|
|
|
myosin filament organization
|
GO:0031033 |
3 |
0.524
|
Zebrafish |
|
|
regulation of transposition
|
GO:0010528 |
2 |
0.518
|
Fly |
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.514
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.504
|
Rat |
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.496
|
Yeast Worm |
|
|
protein targeting
|
GO:0006605 |
143 |
0.475
|
Yeast Rat |
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.474
|
Mouse |
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.468
|
Yeast Worm |
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.467
|
Yeast Worm |
|
|
protein import
|
GO:0017038 |
101 |
0.463
|
Rat |
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
49 |
0.460
|
|
|
|
rna splicing
|
GO:0008380 |
54 |
0.460
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.454
|
Yeast Worm |
|
|
rna dependent dna replication
|
GO:0006278 |
3 |
0.447
|
Yeast |
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.445
|
Yeast Worm |
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.442
|
Zebrafish |
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.441
|
Rat |
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
139 |
0.436
|
Zebrafish |
|
|
spindle assembly involved in mitosis
|
GO:0090307 |
4 |
0.424
|
|
|
|
single fertilization
|
GO:0007338 |
82 |
0.421
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.420
|
|
|
|
positive regulation of dna replication
|
GO:0045740 |
9 |
0.415
|
Yeast |
|
|
actin filament organization
|
GO:0007015 |
113 |
0.414
|
Zebrafish Fly |
|
|
circadian sleep wake cycle
|
GO:0042745 |
5 |
0.414
|
Fly |
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.396
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.391
|
Rat |
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.381
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.370
|
Rat |
|
|
toxin transport
|
GO:1901998 |
38 |
0.369
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.366
|
Rat |
|
|
renal system development
|
GO:0072001 |
225 |
0.364
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.360
|
|
|
|
mitochondrial transport
|
GO:0006839 |
36 |
0.351
|
Yeast |
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.349
|
Rat |
|
|
fertilization
|
GO:0009566 |
127 |
0.347
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.343
|
|
|
|
establishment of protein localization to mitochondrion
|
GO:0072655 |
11 |
0.341
|
Yeast |
|
|
regulation of mrna processing
|
GO:0050684 |
41 |
0.336
|
|
|
|
regulation of protein import into nucleus translocation
|
GO:0033158 |
2 |
0.335
|
Rat |
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.330
|
Yeast Worm |
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.329
|
Fly |
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.328
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.322
|
|
|
|
stress granule disassembly
|
GO:0035617 |
2 |
0.317
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
51 |
0.313
|
|
|
|
purine ribonucleoside monophosphate catabolic process
|
GO:0009169 |
57 |
0.312
|
Yeast Worm |
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.312
|
|
|
|
nuclear import
|
GO:0051170 |
95 |
0.309
|
Rat |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.308
|
Yeast Worm |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.307
|
Yeast Worm |
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.300
|
|
|
|
photoreceptor cell development
|
GO:0042461 |
40 |
0.299
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.299
|
Rat |
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.297
|
|
|
|
cellular response to topologically incorrect protein
|
GO:0035967 |
25 |
0.294
|
|
|
|
ribonucleoprotein complex subunit organization
|
GO:0071826 |
28 |
0.291
|
Yeast |
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.290
|
Yeast Worm |
|
|
gonad development
|
GO:0008406 |
141 |
0.290
|
Worm |
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.289
|
Yeast Worm |
|
|
intracellular steroid hormone receptor signaling pathway
|
GO:0030518 |
29 |
0.274
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.273
|
Fly |
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.268
|
|
|
|
regulation of mrna splicing via spliceosome
|
GO:0048024 |
32 |
0.265
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.264
|
Rat |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.264
|
|
|
|
regulation of rna splicing
|
GO:0043484 |
37 |
0.263
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.260
|
Yeast Worm |
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.257
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
24 |
0.256
|
Worm |
|
|
cell recognition
|
GO:0008037 |
83 |
0.255
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.254
|
Yeast Worm |
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.251
|
Yeast Worm |
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.250
|
Yeast Worm |
|
|
oocyte anterior posterior axis specification
|
GO:0007314 |
2 |
0.247
|
Fly |
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.244
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.244
|
Yeast Rat |
|
|
regulation of microtubule based process
|
GO:0032886 |
52 |
0.243
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.242
|
Rat |
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.242
|
Yeast Worm |
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.230
|
Fly |
|
|
purine nucleoside monophosphate catabolic process
|
GO:0009128 |
58 |
0.223
|
Yeast Worm |
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.222
|
Worm |
|
|
rhythmic process
|
GO:0048511 |
174 |
0.222
|
Fly |
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
57 |
0.220
|
Yeast Worm |
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
73 |
0.220
|
Rat |
|
|
cell growth
|
GO:0016049 |
130 |
0.216
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.215
|
Yeast Worm |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.213
|
|
|
|
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna
|
GO:0000466 |
1 |
0.213
|
|
|
|
response to temperature stimulus
|
GO:0009266 |
55 |
0.213
|
Yeast Rat Fly |
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.212
|
Yeast |
|
|
ribonucleoprotein complex localization
|
GO:0071166 |
1 |
0.209
|
|
|
|
axonal fasciculation
|
GO:0007413 |
15 |
0.208
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.208
|
Yeast Rat |
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.203
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.199
|
Yeast Worm |
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.197
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.193
|
Yeast Worm |
|
|
protein localization to mitochondrion
|
GO:0070585 |
15 |
0.193
|
Yeast |
|
|
response to topologically incorrect protein
|
GO:0035966 |
25 |
0.190
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.189
|
Fly |
|
|
organelle localization
|
GO:0051640 |
179 |
0.184
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.182
|
Yeast Worm |
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.182
|
Yeast Worm |
|
|
protein targeting to membrane
|
GO:0006612 |
20 |
0.181
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
54 |
0.179
|
|
|
|
regulation of centrosome cycle
|
GO:0046605 |
10 |
0.175
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.175
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.173
|
|
|
|
macromolecular complex disassembly
|
GO:0032984 |
43 |
0.173
|
|
|
|
pore complex assembly
|
GO:0046931 |
3 |
0.172
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
115 |
0.168
|
|
|
|
cellular response to interleukin 4
|
GO:0071353 |
21 |
0.167
|
Mouse |
|
|
translation
|
GO:0006412 |
93 |
0.165
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.162
|
Yeast Worm |
|
|
gene silencing by rna
|
GO:0031047 |
19 |
0.161
|
|
|
|
pole plasm assembly
|
GO:0007315 |
2 |
0.160
|
Fly |
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.159
|
Yeast Worm |
|
|
cellular response to heat
|
GO:0034605 |
15 |
0.154
|
Yeast |
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.154
|
Yeast Worm |
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.153
|
|
|
|
positive regulation of mrna metabolic process
|
GO:1903313 |
17 |
0.152
|
|
|
|
spindle organization
|
GO:0007051 |
28 |
0.151
|
Fly |
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
42 |
0.151
|
Rat |
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.143
|
Yeast Worm |
|
|
regulation of protein stability
|
GO:0031647 |
52 |
0.140
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.140
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.139
|
Yeast Worm |
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.139
|
|
|
|
genitalia development
|
GO:0048806 |
37 |
0.138
|
Worm |
|
|
cytokine production involved in immune response
|
GO:0002367 |
34 |
0.137
|
|
|
|
response to interleukin 4
|
GO:0070670 |
23 |
0.136
|
Mouse |
|
|
regulation of circadian sleep wake cycle sleep
|
GO:0045187 |
3 |
0.136
|
Fly |
|
|
positive regulation of mrna processing
|
GO:0050685 |
16 |
0.136
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.135
|
|
|
|
regulation of circadian rhythm
|
GO:0042752 |
58 |
0.135
|
Fly |
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.133
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
56 |
0.131
|
Zebrafish |
|
|
centrosome duplication
|
GO:0051298 |
16 |
0.126
|
|
|
|
habituation
|
GO:0046959 |
3 |
0.126
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.123
|
Fly |
|
|
protein targeting to er
|
GO:0045047 |
2 |
0.121
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.120
|
|
|
|
regulation of dna replication
|
GO:0006275 |
17 |
0.119
|
Yeast |
|
|
regulation of polyamine transmembrane transport
|
GO:1902267 |
5 |
0.116
|
|
|
|
posttranscriptional gene silencing
|
GO:0016441 |
10 |
0.116
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.112
|
Yeast |
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.110
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.109
|
Rat |
|
|
telomere maintenance via telomerase
|
GO:0007004 |
1 |
0.108
|
Yeast |
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
85 |
0.108
|
Yeast Worm |
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.106
|
Rat |
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.105
|
Rat |
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.105
|
Yeast Worm |
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.103
|
Rat |
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.103
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.103
|
|
|
|
rna localization
|
GO:0006403 |
23 |
0.102
|
Fly |
|
|
regulation of microtubule cytoskeleton organization
|
GO:0070507 |
37 |
0.102
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.101
|
Yeast Worm |
|
|
response to osmotic stress
|
GO:0006970 |
21 |
0.101
|
Yeast Rat |
|
|
rna interference
|
GO:0016246 |
2 |
0.101
|
|
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.101
|
Zebrafish |
|
|
protein depolymerization
|
GO:0051261 |
34 |
0.100
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.100
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.100
|
Yeast Worm |
|
|
atp metabolic process
|
GO:0046034 |
75 |
0.096
|
Yeast Worm |
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
80 |
0.096
|
Yeast Worm |
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.096
|
Fly |
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.096
|
Rat |
|
|
oogenesis
|
GO:0048477 |
56 |
0.095
|
Fly |
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
87 |
0.092
|
|
|
|
nitric oxide metabolic process
|
GO:0046209 |
25 |
0.091
|
|
|
|
kidney development
|
GO:0001822 |
213 |
0.091
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.087
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.087
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.087
|
Zebrafish Fly |
|
|
circadian behavior
|
GO:0048512 |
13 |
0.087
|
Fly |
|
|
oocyte construction
|
GO:0007308 |
2 |
0.087
|
Fly |
|
|
mrna metabolic process
|
GO:0016071 |
84 |
0.085
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.085
|
|
|
|
negative regulation of inclusion body assembly
|
GO:0090084 |
1 |
0.084
|
|
|
|
hindbrain development
|
GO:0030902 |
128 |
0.084
|
|
|
|
regulation of mrna metabolic process
|
GO:1903311 |
43 |
0.083
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.083
|
Yeast Worm |
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.083
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
11 |
0.081
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.080
|
Yeast Worm |
|
|
regulation of cell size
|
GO:0008361 |
72 |
0.079
|
Rat |
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.078
|
|
|
|
er nucleus signaling pathway
|
GO:0006984 |
27 |
0.077
|
|
|
|
protein dna complex subunit organization
|
GO:0071824 |
28 |
0.077
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.076
|
|
|
|
regulation of nuclear transcribed mrna poly a tail shortening
|
GO:0060211 |
4 |
0.076
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.075
|
Yeast Worm |
|
|
chromatin organization
|
GO:0006325 |
206 |
0.074
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.074
|
Yeast |
|
|
neural nucleus development
|
GO:0048857 |
22 |
0.073
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.073
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.073
|
Yeast Worm |
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.072
|
|
|
|
positive regulation of rna splicing
|
GO:0033120 |
12 |
0.072
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.071
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
76 |
0.069
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.069
|
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.067
|
|
|
|
striated muscle myosin thick filament assembly
|
GO:0071688 |
1 |
0.067
|
Zebrafish |
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
74 |
0.067
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.067
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.066
|
|
|
|
female gamete generation
|
GO:0007292 |
74 |
0.066
|
Fly |
|
|
microtubule polymerization or depolymerization
|
GO:0031109 |
26 |
0.066
|
|
|
|
rna splicing via transesterification reactions
|
GO:0000375 |
43 |
0.066
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
52 |
0.065
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.064
|
|
|
|
dna replication
|
GO:0006260 |
52 |
0.063
|
Yeast |
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.063
|
Yeast Worm |
|
|
mapk cascade
|
GO:0000165 |
281 |
0.063
|
|
|
|
negative regulation of synapse assembly
|
GO:0051964 |
3 |
0.063
|
|
|
|
positive regulation of protein import into nucleus
|
GO:0042307 |
26 |
0.061
|
Rat |
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.061
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.060
|
Fly |
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.060
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.060
|
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
81 |
0.060
|
Yeast Worm |
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
41 |
0.060
|
|
|
|
protein complex disassembly
|
GO:0043241 |
40 |
0.059
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.058
|
Yeast Worm |
|
|
carbohydrate biosynthetic process
|
GO:0016051 |
74 |
0.058
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.058
|
Yeast Worm |
|
|
actin filament polymerization
|
GO:0030041 |
44 |
0.058
|
|
|
|
t cell mediated immunity
|
GO:0002456 |
50 |
0.057
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.057
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.057
|
|
|
|
detection of stimulus
|
GO:0051606 |
84 |
0.057
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.057
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.057
|
Yeast Worm |
|
|
response to uv a
|
GO:0070141 |
1 |
0.056
|
|
|
|
gene silencing
|
GO:0016458 |
38 |
0.056
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.056
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.056
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.055
|
|
|
|
mitotic spindle organization
|
GO:0007052 |
10 |
0.055
|
Fly |
|
|
negative regulation of cell projection organization
|
GO:0031345 |
56 |
0.055
|
|
|
|
positive regulation of binding
|
GO:0051099 |
49 |
0.054
|
|
|
|
positive regulation of lymphocyte mediated immunity
|
GO:0002708 |
62 |
0.054
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.053
|
Rat |
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.053
|
Rat |
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.053
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.052
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.052
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
61 |
0.051
|
Rat |
|
|
positive regulation of protein import into nucleus translocation
|
GO:0033160 |
1 |
0.050
|
Rat |
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
62 |
0.050
|
|
|
|
spindle assembly
|
GO:0051225 |
13 |
0.050
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
45 |
0.050
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.050
|
|
|
|
mrna splicing via spliceosome
|
GO:0000398 |
43 |
0.050
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.049
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.049
|
|
|
|
protein localization to membrane
|
GO:0072657 |
108 |
0.049
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
121 |
0.049
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.049
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
92 |
0.049
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.049
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.049
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.049
|
|
|
|
negative regulation of rna splicing
|
GO:0033119 |
12 |
0.048
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.048
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.047
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.047
|
|
|
|
negative regulation of neuron death
|
GO:1901215 |
98 |
0.047
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.046
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
83 |
0.046
|
Yeast |
|
|
interleukin 5 secretion
|
GO:0072603 |
2 |
0.046
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.046
|
Yeast |
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.045
|
Rat |
|
|
maintenance of location
|
GO:0051235 |
89 |
0.045
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.045
|
|
|
|
establishment of protein localization to endoplasmic reticulum
|
GO:0072599 |
2 |
0.044
|
|
|
|
mrna 3 end processing
|
GO:0031124 |
16 |
0.043
|
|
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
92 |
0.043
|
|
|
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
59 |
0.043
|
Yeast Worm |
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.043
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
80 |
0.043
|
Yeast Worm |
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.043
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.042
|
Fly |
|
|
chromatin modification
|
GO:0016568 |
187 |
0.042
|
|
|
|
intracellular mrna localization
|
GO:0008298 |
4 |
0.042
|
Fly |
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.042
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.041
|
Rat |
|
|
nitric oxide biosynthetic process
|
GO:0006809 |
25 |
0.041
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.040
|
Yeast Worm |
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.040
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.040
|
|
|
|
glycogen biosynthetic process
|
GO:0005978 |
14 |
0.040
|
|
|
|
positive regulation of immune response to tumor cell
|
GO:0002839 |
6 |
0.040
|
|
|
|
mrna processing
|
GO:0006397 |
63 |
0.040
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
88 |
0.040
|
|
|
|
spermatid differentiation
|
GO:0048515 |
115 |
0.040
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.039
|
|
|
|
regulation of circadian sleep wake cycle
|
GO:0042749 |
3 |
0.039
|
Fly |
|
|
rrna containing ribonucleoprotein complex export from nucleus
|
GO:0071428 |
1 |
0.038
|
|
|
|
regeneration
|
GO:0031099 |
38 |
0.038
|
|
|
|
cerebellum development
|
GO:0021549 |
77 |
0.037
|
|
|
|
cardiac muscle cell differentiation
|
GO:0055007 |
69 |
0.037
|
|
|
|
neuron recognition
|
GO:0008038 |
25 |
0.036
|
|
|
|
sperm motility
|
GO:0030317 |
47 |
0.036
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.036
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
11 |
0.036
|
Worm |
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.036
|
|
|
|
spermatid development
|
GO:0007286 |
108 |
0.036
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.035
|
|
|
|
glucan metabolic process
|
GO:0044042 |
32 |
0.035
|
|
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.035
|
|
|
|
mitotic cytokinesis
|
GO:0000281 |
4 |
0.034
|
|
|
|
mitotic chromosome condensation
|
GO:0007076 |
1 |
0.034
|
|
|
|
fatty acid transmembrane transport
|
GO:1902001 |
1 |
0.034
|
|
|
|
regulation of cell shape
|
GO:0008360 |
39 |
0.034
|
Fly |
|
|
meiotic cell cycle process
|
GO:1903046 |
77 |
0.034
|
|
|
|
cellular response to inorganic substance
|
GO:0071241 |
37 |
0.034
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.033
|
|
|
|
positive regulation of nitric oxide biosynthetic process
|
GO:0045429 |
14 |
0.033
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.033
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.032
|
|
|
|
protein export from nucleus
|
GO:0006611 |
20 |
0.032
|
|
|
|
ear development
|
GO:0043583 |
200 |
0.032
|
|
|
|
placenta development
|
GO:0001890 |
140 |
0.032
|
Mouse |
|
|
neuron projection regeneration
|
GO:0031102 |
14 |
0.032
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.032
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
119 |
0.032
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.032
|
|
|
|
regulation of protein binding
|
GO:0043393 |
60 |
0.031
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.031
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.031
|
Rat |
|
|
protein polymerization
|
GO:0051258 |
57 |
0.031
|
|
|
|
retina homeostasis
|
GO:0001895 |
23 |
0.030
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.030
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
54 |
0.030
|
|
|
|
ribosomal small subunit biogenesis
|
GO:0042274 |
4 |
0.030
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.029
|
|
|
|
dna packaging
|
GO:0006323 |
30 |
0.029
|
|
|
|
oocyte development
|
GO:0048599 |
33 |
0.029
|
Fly |
|
|
cd4 positive alpha beta t cell cytokine production
|
GO:0035743 |
4 |
0.029
|
|
|
|
cerebellar cortex development
|
GO:0021695 |
48 |
0.029
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.029
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.029
|
|
|
|
response to metal ion
|
GO:0010038 |
47 |
0.029
|
|
|
|
midgut development
|
GO:0007494 |
4 |
0.029
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
59 |
0.028
|
|
|
|
response to oxygen levels
|
GO:0070482 |
62 |
0.027
|
|
|
|
cell maturation
|
GO:0048469 |
127 |
0.027
|
Fly |
|
|
energy reserve metabolic process
|
GO:0006112 |
39 |
0.027
|
|
|
|
t helper 2 cell cytokine production
|
GO:0035745 |
4 |
0.027
|
|
|
|
plasma membrane organization
|
GO:0007009 |
90 |
0.027
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.027
|
|
|
|
interleukin 10 secretion
|
GO:0072608 |
4 |
0.027
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.027
|
|
|
|
cilium morphogenesis
|
GO:0060271 |
102 |
0.026
|
|
|
|
regulation of ral protein signal transduction
|
GO:0032485 |
4 |
0.026
|
|
|
|
negative regulation of filopodium assembly
|
GO:0051490 |
2 |
0.026
|
|
|
|
cerebellum morphogenesis
|
GO:0021587 |
42 |
0.026
|
|
|
|
response to calcium ion
|
GO:0051592 |
20 |
0.026
|
|
|
|
positive regulation of interleukin 10 production
|
GO:0032733 |
12 |
0.026
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.026
|
|
|
|
glucocorticoid receptor signaling pathway
|
GO:0042921 |
7 |
0.026
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
96 |
0.026
|
|
|
|
positive regulation of protein binding
|
GO:0032092 |
29 |
0.026
|
|
|
|
male sex differentiation
|
GO:0046661 |
109 |
0.026
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.026
|
Yeast Worm |
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.025
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.025
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.025
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
130 |
0.025
|
|
|
|
regulation of actin filament depolymerization
|
GO:0030834 |
13 |
0.025
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.025
|
|
|
|
neural tube development
|
GO:0021915 |
160 |
0.025
|
|
|
|
regulation of protein processing
|
GO:0070613 |
96 |
0.025
|
|
|
|
response to morphine
|
GO:0043278 |
9 |
0.025
|
|
|
|
nucleus localization
|
GO:0051647 |
20 |
0.025
|
|
|
|
response to alkaloid
|
GO:0043279 |
34 |
0.025
|
|
|
|
regulation of neurotransmitter levels
|
GO:0001505 |
87 |
0.024
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.024
|
|
|
|
polyamine biosynthetic process
|
GO:0006596 |
2 |
0.024
|
|
|
|
sleep
|
GO:0030431 |
7 |
0.024
|
Fly |
|
|
cation transport
|
GO:0006812 |
399 |
0.024
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.024
|
|
|
|
plasma membrane long chain fatty acid transport
|
GO:0015911 |
1 |
0.024
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.024
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.024
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.024
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.024
|
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.023
|
|
|
|
response to uv
|
GO:0009411 |
44 |
0.023
|
|
|
|
telomere maintenance via telomere lengthening
|
GO:0010833 |
4 |
0.023
|
Yeast |
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
57 |
0.023
|
|
|
|
endoplasmic reticulum unfolded protein response
|
GO:0030968 |
19 |
0.023
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.023
|
|
|
|
metencephalon development
|
GO:0022037 |
89 |
0.023
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.022
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.022
|
|
|
|
ribosome biogenesis
|
GO:0042254 |
20 |
0.022
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.022
|
|
|
|
polyamine transport
|
GO:0015846 |
5 |
0.022
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
61 |
0.022
|
|
|
|
prostaglandin metabolic process
|
GO:0006693 |
11 |
0.022
|
|
|
|
substantia nigra development
|
GO:0021762 |
2 |
0.022
|
|
|
|
maturation of lsu rrna
|
GO:0000470 |
1 |
0.022
|
|
|
|
body morphogenesis
|
GO:0010171 |
45 |
0.021
|
|
|
|
positive regulation of mrna splicing via spliceosome
|
GO:0048026 |
11 |
0.021
|
|
|
|
negative regulation of fatty acid transport
|
GO:2000192 |
1 |
0.021
|
|
|
|
fatty acid biosynthetic process
|
GO:0006633 |
41 |
0.021
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.021
|
|
|
|
cotranslational protein targeting to membrane
|
GO:0006613 |
2 |
0.021
|
|
|
|
actin filament based movement
|
GO:0030048 |
23 |
0.020
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.020
|
|
|
|
energy derivation by oxidation of organic compounds
|
GO:0015980 |
77 |
0.020
|
|
|
|
neurotransmitter transport
|
GO:0006836 |
76 |
0.020
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.020
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.020
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.020
|
|
|
|
cellular glucan metabolic process
|
GO:0006073 |
32 |
0.020
|
|
|
|
anion transport
|
GO:0006820 |
177 |
0.020
|
|
|
|
adult behavior
|
GO:0030534 |
135 |
0.020
|
|
|
|
synapse assembly
|
GO:0007416 |
56 |
0.020
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.020
|
Zebrafish |
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.020
|
|
|
|
female sex determination
|
GO:0030237 |
1 |
0.020
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
56 |
0.019
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.019
|
|
|
|
embryonic eye morphogenesis
|
GO:0048048 |
29 |
0.019
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.019
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
65 |
0.019
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.019
|
|
|
|
regulation of mrna 3 end processing
|
GO:0031440 |
6 |
0.019
|
|
|
|
misfolded protein transport
|
GO:0070843 |
1 |
0.019
|
|
|
|
carbohydrate homeostasis
|
GO:0033500 |
128 |
0.019
|
|
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
61 |
0.019
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.019
|
|
|
|
maturation of 5 8s rrna
|
GO:0000460 |
1 |
0.019
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.019
|
Rat |
|
|
endodermal digestive tract morphogenesis
|
GO:0061031 |
4 |
0.018
|
|
|
|
polysaccharide biosynthetic process
|
GO:0000271 |
20 |
0.018
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.018
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.018
|
|
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
86 |
0.018
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
83 |
0.018
|
|
|
|
response to unfolded protein
|
GO:0006986 |
21 |
0.018
|
|
|
|
glycogen metabolic process
|
GO:0005977 |
32 |
0.018
|
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.018
|
|
|
|
eye photoreceptor cell development
|
GO:0042462 |
31 |
0.018
|
|
|
|
cellular response to granulocyte macrophage colony stimulating factor stimulus
|
GO:0097011 |
3 |
0.018
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.018
|
|
|
|
regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0000079 |
16 |
0.017
|
|
|
|
maternal determination of anterior posterior axis embryo
|
GO:0008358 |
2 |
0.017
|
Fly |
|
|
regulation of ubiquitin protein ligase activity involved in mitotic cell cycle
|
GO:0051439 |
1 |
0.017
|
|
