Mus musculus

104 known processes

Hspa1b

heat shock protein 1B

(Aliases: Hsp70.1,Hsp70,hsp68,Hsp70-1)

Hspa1b biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
response to heat GO:0009408 27 0.888
telomere maintenance GO:0000723 19 0.863
activation of nf kappab inducing kinase activity GO:0007250 4 0.838
negative regulation of inclusion body assembly GO:0090084 1 0.725
protein refolding GO:0042026 1 0.662
dna metabolic process GO:0006259 303 0.644
cellular response to dna damage stimulus GO:0006974 207 0.573
cellular protein catabolic process GO:0044257 155 0.499
regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway GO:1902235 11 0.444
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.433
response to temperature stimulus GO:0009266 55 0.418
anatomical structure homeostasis GO:0060249 145 0.369
dephosphorylation GO:0016311 129 0.323
ubiquitin dependent protein catabolic process GO:0006511 129 0.309
proteasomal protein catabolic process GO:0010498 98 0.282
negative regulation of cellular protein metabolic process GO:0032269 247 0.276
positive regulation of cell death GO:0010942 224 0.275
cellular macromolecule catabolic process GO:0044265 206 0.274
intrinsic apoptotic signaling pathway GO:0097193 132 0.254
cellular amino acid metabolic process GO:0006520 103 0.249
positive regulation of cellular amine metabolic process GO:0033240 5 0.219
fibroblast migration GO:0010761 21 0.203
misfolded protein transport GO:0070843 1 0.202
actin cytoskeleton organization GO:0030036 220 0.200
regulation of cell motility GO:2000145 236 0.192
regulation of protein serine threonine kinase activity GO:0071900 157 0.181
modification dependent protein catabolic process GO:0019941 133 0.172
regulation of transferase activity GO:0051338 263 0.171
positive regulation of protein phosphorylation GO:0001934 242 0.159
inclusion body assembly GO:0070841 3 0.158
protein modification by small protein conjugation GO:0032446 187 0.154
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.150
positive regulation of protein complex assembly GO:0031334 45 0.147
negative regulation of phosphorus metabolic process GO:0010563 184 0.144
purine ribonucleoside catabolic process GO:0046130 205 0.143
regulation of actin filament polymerization GO:0030833 38 0.135
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.135
negative regulation of hydrolase activity GO:0051346 71 0.134
actin polymerization or depolymerization GO:0008154 54 0.132
actin filament polymerization GO:0030041 44 0.128
organonitrogen compound catabolic process GO:1901565 264 0.128
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.126
cellular ketone metabolic process GO:0042180 84 0.123
cellular response to external stimulus GO:0071496 88 0.116
cellular response to misfolded protein GO:0071218 5 0.114
negative regulation of phosphate metabolic process GO:0045936 184 0.113
negative regulation of jun kinase activity GO:0043508 9 0.112
regulation of actin filament length GO:0030832 45 0.109
regulation of actin filament bundle assembly GO:0032231 18 0.108
cellular protein complex assembly GO:0043623 116 0.108
actin filament organization GO:0007015 113 0.107
negative regulation of transferase activity GO:0051348 85 0.106
positive regulation of apoptotic process GO:0043065 217 0.103
ribonucleoside triphosphate catabolic process GO:0009203 199 0.102
peptidyl amino acid modification GO:0018193 336 0.102
regulation of cellular component biogenesis GO:0044087 181 0.102
nucleoside triphosphate metabolic process GO:0009141 230 0.100
regulation of kinase activity GO:0043549 249 0.100
response to epidermal growth factor GO:0070849 4 0.100
cytokine production GO:0001816 319 0.099
regulation of protein kinase activity GO:0045859 232 0.097
ribose phosphate metabolic process GO:0019693 291 0.094
atp catabolic process GO:0006200 55 0.092
purine containing compound catabolic process GO:0072523 213 0.086
positive regulation of actin filament polymerization GO:0030838 26 0.084
negative regulation of molecular function GO:0044092 258 0.084
macromolecule catabolic process GO:0009057 281 0.084
response to lipopolysaccharide GO:0032496 128 0.083
response to molecule of bacterial origin GO:0002237 143 0.083
positive regulation of organelle organization GO:0010638 128 0.081
protein catabolic process GO:0030163 221 0.081
response to endoplasmic reticulum stress GO:0034976 53 0.080
negative regulation of map kinase activity GO:0043407 34 0.079
nucleotide metabolic process GO:0009117 332 0.078
response to topologically incorrect protein GO:0035966 25 0.077
i kappab kinase nf kappab signaling GO:0007249 85 0.076
lung development GO:0030324 164 0.076
jnk cascade GO:0007254 72 0.075
organophosphate catabolic process GO:0046434 232 0.075
glycosyl compound catabolic process GO:1901658 206 0.075
purine nucleotide catabolic process GO:0006195 211 0.075
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 34 0.075
nucleoside monophosphate metabolic process GO:0009123 85 0.075
negative regulation of intracellular signal transduction GO:1902532 167 0.075
response to growth factor GO:0070848 198 0.073
cellular amine metabolic process GO:0044106 44 0.073
nucleoside triphosphate catabolic process GO:0009143 205 0.072
ribonucleoside metabolic process GO:0009119 245 0.071
regulation of cell migration GO:0030334 219 0.070
purine nucleoside triphosphate catabolic process GO:0009146 203 0.070
positive regulation of atpase activity GO:0032781 3 0.069
amine metabolic process GO:0009308 45 0.068
regulation of inclusion body assembly GO:0090083 1 0.068
regulation of cellular amino acid metabolic process GO:0006521 5 0.066
regulation of cellular response to stress GO:0080135 159 0.065
muscle tissue development GO:0060537 308 0.065
regulation of cytokine production GO:0001817 266 0.065
purine ribonucleotide catabolic process GO:0009154 208 0.064
ribonucleotide catabolic process GO:0009261 208 0.064
modification dependent macromolecule catabolic process GO:0043632 133 0.064
cell adhesion GO:0007155 329 0.064
regulation of cellular ketone metabolic process GO:0010565 66 0.062
response to oxidative stress GO:0006979 123 0.062
heterocycle catabolic process GO:0046700 280 0.062
regulation of protein complex assembly GO:0043254 83 0.062
protein polymerization GO:0051258 57 0.062
negative regulation of protein metabolic process GO:0051248 282 0.061
regulation of organelle organization GO:0033043 289 0.061
peptidyl serine modification GO:0018209 83 0.060
regulation of actin polymerization or depolymerization GO:0008064 45 0.059
apoptotic signaling pathway GO:0097190 306 0.059
response to organic cyclic compound GO:0014070 198 0.058
regulation of jun kinase activity GO:0043506 40 0.057
negative regulation of cell proliferation GO:0008285 296 0.056
purine ribonucleoside metabolic process GO:0046128 241 0.056
regulation of cellular catabolic process GO:0031329 242 0.055
negative regulation of cellular amine metabolic process GO:0033239 1 0.055
regulation of cellular component size GO:0032535 121 0.055
regulation of apoptotic signaling pathway GO:2001233 197 0.055
negative regulation of immune system process GO:0002683 209 0.054
ribonucleoside monophosphate metabolic process GO:0009161 80 0.054
purine nucleoside triphosphate metabolic process GO:0009144 226 0.054
positive regulation of protein kinase activity GO:0045860 144 0.053
ribonucleotide metabolic process GO:0009259 291 0.053
carbohydrate derivative catabolic process GO:1901136 231 0.053
regulation of cell adhesion GO:0030155 154 0.052
mapk cascade GO:0000165 281 0.052
ribonucleoside catabolic process GO:0042454 206 0.052
actin filament bundle assembly GO:0051017 40 0.051
response to acid chemical GO:0001101 111 0.051
endomembrane system organization GO:0010256 147 0.051
regulation of protein maturation GO:1903317 96 0.050
cellular response to abiotic stimulus GO:0071214 56 0.049
nucleotide catabolic process GO:0009166 217 0.049
nucleobase containing small molecule metabolic process GO:0055086 352 0.048
positive regulation of protein modification process GO:0031401 299 0.048
regulation of anatomical structure size GO:0090066 178 0.048
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.048
purine containing compound metabolic process GO:0072521 311 0.048
positive regulation of cellular catabolic process GO:0031331 148 0.048
negative regulation of dephosphorylation GO:0035305 9 0.047
protein folding GO:0006457 28 0.047
positive regulation of cell motility GO:2000147 116 0.047
negative regulation of kinase activity GO:0033673 81 0.046
olfactory learning GO:0008355 2 0.045
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.045
nucleoside phosphate catabolic process GO:1901292 222 0.045
protein maturation GO:0051604 176 0.045
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.045
actomyosin structure organization GO:0031032 56 0.044
positive regulation of cytoskeleton organization GO:0051495 49 0.044
reactive oxygen species metabolic process GO:0072593 84 0.044
positive regulation of cell adhesion GO:0045785 80 0.043
purine nucleoside catabolic process GO:0006152 205 0.043
muscle system process GO:0003012 141 0.043
positive regulation of innate immune response GO:0045089 80 0.043
rhythmic process GO:0048511 174 0.043
angiogenesis GO:0001525 201 0.042
response to organonitrogen compound GO:0010243 246 0.042
regulation of map kinase activity GO:0043405 120 0.041
regulation of protein processing GO:0070613 96 0.041
protein ubiquitination GO:0016567 171 0.041
regulation of jnk cascade GO:0046328 62 0.040
regulation of atp catabolic process GO:1903289 9 0.040
regulation of mapk cascade GO:0043408 248 0.040
regulation of defense response GO:0031347 233 0.040
cellular response to cytokine stimulus GO:0071345 189 0.040
nucleocytoplasmic transport GO:0006913 139 0.039
purine nucleoside monophosphate catabolic process GO:0009128 58 0.039
embryonic placenta development GO:0001892 98 0.039
regulation of nucleotide metabolic process GO:0006140 169 0.039
intracellular protein transport GO:0006886 204 0.038
negative regulation of protein modification process GO:0031400 163 0.037
cell growth GO:0016049 130 0.037
activation of immune response GO:0002253 138 0.036
cellular homeostasis GO:0019725 240 0.036
positive regulation of cell migration GO:0030335 109 0.036
ameboidal type cell migration GO:0001667 128 0.036
protein localization to cell junction GO:1902414 3 0.035
purine ribonucleotide metabolic process GO:0009150 290 0.035
regulation of cellular amine metabolic process GO:0033238 20 0.035
striated muscle myosin thick filament assembly GO:0071688 1 0.035
negative regulation of protein processing GO:0010955 79 0.034
regulation of innate immune response GO:0045088 91 0.034
ruffle organization GO:0031529 16 0.034
positive regulation of fibroblast migration GO:0010763 5 0.034
regulation of actin cytoskeleton organization GO:0032956 84 0.034
signal transduction in absence of ligand GO:0038034 55 0.034
cytoplasmic transport GO:0016482 234 0.033
negative regulation of lymphocyte activation GO:0051250 91 0.033
muscle cell apoptotic process GO:0010657 18 0.033
positive regulation of leukocyte differentiation GO:1902107 86 0.033
cellular response to inorganic substance GO:0071241 37 0.033
regulation of membrane potential GO:0042391 192 0.033
aromatic compound catabolic process GO:0019439 286 0.033
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.032
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.032
regulation of protein catabolic process GO:0042176 108 0.032
membrane organization GO:0061024 245 0.032
cell type specific apoptotic process GO:0097285 268 0.032
mitotic cell cycle process GO:1903047 159 0.032
negative regulation of cellular component organization GO:0051129 194 0.032
labyrinthine layer development GO:0060711 49 0.031
respiratory tube development GO:0030323 167 0.031
regulation of cytokine biosynthetic process GO:0042035 59 0.031
spermatogenesis GO:0007283 284 0.031
organelle disassembly GO:1903008 2 0.031
cellular response to lipid GO:0071396 145 0.031
positive regulation of mapk cascade GO:0043410 170 0.031
compound eye development GO:0048749 1 0.031
response to light stimulus GO:0009416 135 0.031
regulation of cell cycle GO:0051726 281 0.031
protein localization to membrane GO:0072657 108 0.031
skeletal muscle organ development GO:0060538 163 0.031
regulation of epithelial cell proliferation GO:0050678 141 0.031
regulation of hydrolase activity GO:0051336 246 0.030
muscle contraction GO:0006936 101 0.029
neuron death GO:0070997 154 0.029
nucleoside monophosphate catabolic process GO:0009125 59 0.029
myeloid cell differentiation GO:0030099 233 0.029
oxidation reduction process GO:0055114 342 0.029
i kappab phosphorylation GO:0007252 6 0.029
immune effector process GO:0002252 321 0.029
positive regulation of antibacterial peptide biosynthetic process GO:0006963 1 0.029
transmembrane transport GO:0055085 412 0.028
covalent chromatin modification GO:0016569 163 0.028
neurotransmitter transport GO:0006836 76 0.028
negative regulation of mapk cascade GO:0043409 65 0.028
antibacterial peptide biosynthetic process GO:0002780 2 0.028
negative regulation of response to endoplasmic reticulum stress GO:1903573 8 0.028
myosin filament assembly GO:0031034 2 0.028
histone modification GO:0016570 159 0.027
cytokine biosynthetic process GO:0042089 68 0.027
regulation of stress activated mapk cascade GO:0032872 69 0.027
muscle cell differentiation GO:0042692 261 0.027
reactive nitrogen species metabolic process GO:2001057 0 0.027
positive regulation of atp catabolic process GO:1903291 3 0.027
regulation of nik nf kappab signaling GO:1901222 10 0.027
regulation of nucleotide catabolic process GO:0030811 122 0.027
negative regulation of apoptotic signaling pathway GO:2001234 104 0.027
regulation of reactive oxygen species metabolic process GO:2000377 40 0.027
single organism cell adhesion GO:0098602 156 0.027
midgut development GO:0007494 4 0.027
purine nucleoside metabolic process GO:0042278 241 0.027
ribonucleoside triphosphate metabolic process GO:0009199 220 0.026
regulation of purine nucleotide metabolic process GO:1900542 169 0.026
regulation of defense response to bacterium GO:1900424 3 0.026
protein localization to nucleus GO:0034504 121 0.026
regulation of antibacterial peptide biosynthetic process GO:0002808 1 0.026
regulation of cellular protein catabolic process GO:1903362 61 0.026
regulation of leukocyte differentiation GO:1902105 159 0.026
stress activated mapk cascade GO:0051403 80 0.026
lymphocyte mediated immunity GO:0002449 139 0.026
regulation of protein localization GO:0032880 231 0.026
regulation of tumor necrosis factor production GO:0032680 49 0.026
nucleoside catabolic process GO:0009164 206 0.026
oocyte construction GO:0007308 2 0.026
protein modification by small protein conjugation or removal GO:0070647 207 0.025
negative regulation of protein maturation GO:1903318 79 0.025
regulation of nucleoside metabolic process GO:0009118 130 0.025
carbohydrate metabolic process GO:0005975 230 0.025
positive regulation of stress fiber assembly GO:0051496 9 0.025
axonogenesis GO:0007409 274 0.025
peptidyl lysine modification GO:0018205 77 0.025
de novo protein folding GO:0006458 9 0.025
oocyte axis specification GO:0007309 2 0.025
negative regulation of proteolysis GO:0045861 74 0.025
antibacterial peptide production GO:0002778 2 0.025
positive regulation of nf kappab transcription factor activity GO:0051092 30 0.025
mitochondrion organization GO:0007005 134 0.025
cellular response to topologically incorrect protein GO:0035967 25 0.025
regulation of establishment of protein localization GO:0070201 181 0.024
cellular response to epidermal growth factor stimulus GO:0071364 4 0.024
purine nucleoside monophosphate metabolic process GO:0009126 81 0.024
chromatin organization GO:0006325 206 0.024
chromatin modification GO:0016568 187 0.024
synaptic transmission GO:0007268 329 0.024
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.024
negative regulation of defense response GO:0031348 77 0.024
cellular nitrogen compound catabolic process GO:0044270 280 0.024
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.024
regulation of erk1 and erk2 cascade GO:0070372 71 0.024
regulation of intracellular transport GO:0032386 159 0.024
positive regulation of programmed cell death GO:0043068 218 0.023
positive regulation of cellular component biogenesis GO:0044089 94 0.023
camera type eye development GO:0043010 266 0.023
leukocyte proliferation GO:0070661 172 0.023
sperm motility GO:0030317 47 0.023
organic cyclic compound catabolic process GO:1901361 295 0.023
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.023
purine nucleotide metabolic process GO:0006163 302 0.023
regulation of transporter activity GO:0032409 57 0.023
atp metabolic process GO:0046034 75 0.023
regulation of dephosphorylation GO:0035303 18 0.023
cellular response to lipopolysaccharide GO:0071222 77 0.023
microtubule cytoskeleton organization GO:0000226 157 0.022
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 34 0.022
toll like receptor signaling pathway GO:0002224 38 0.022
learning GO:0007612 98 0.022
cell activation involved in immune response GO:0002263 126 0.022
positive regulation of defense response GO:0031349 124 0.022
glycosyl compound metabolic process GO:1901657 246 0.022
positive regulation of nucleotide catabolic process GO:0030813 88 0.022
negative regulation of cysteine type endopeptidase activity GO:2000117 22 0.022
stress activated protein kinase signaling cascade GO:0031098 81 0.022
male gamete generation GO:0048232 285 0.022
regulation of protein kinase b signaling GO:0051896 56 0.022
cellular ion homeostasis GO:0006873 165 0.021
response to reactive oxygen species GO:0000302 56 0.021
regulation of actin filament based process GO:0032970 99 0.021
negative regulation of ripoptosome assembly involved in necroptotic process GO:1902443 3 0.021
tissue homeostasis GO:0001894 115 0.021
telencephalon development GO:0021537 186 0.021
production of molecular mediator of immune response GO:0002440 103 0.021
regulation of cell activation GO:0050865 289 0.021
regulation of purine nucleotide catabolic process GO:0033121 122 0.021
positive regulation of kinase activity GO:0033674 155 0.021
homeostasis of number of cells GO:0048872 210 0.021
leukocyte differentiation GO:0002521 342 0.021
negative regulation of phosphorylation GO:0042326 166 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.021
regulation of adaptive immune response GO:0002819 90 0.021
locomotory behavior GO:0007626 195 0.020
positive regulation of transferase activity GO:0051347 167 0.020
intermediate filament cytoskeleton organization GO:0045104 26 0.020
cellular response to starvation GO:0009267 57 0.020
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.020
negative regulation of protein phosphorylation GO:0001933 126 0.020
extrinsic apoptotic signaling pathway GO:0097191 126 0.020
wound healing GO:0042060 157 0.020
skin development GO:0043588 220 0.020
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.020
regulation of fibroblast migration GO:0010762 12 0.020
circadian rhythm GO:0007623 114 0.020
phagocytosis GO:0006909 66 0.019
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.019
response to starvation GO:0042594 65 0.019
positive regulation of cell cycle GO:0045787 92 0.019
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.019
regulation of multi organism process GO:0043900 111 0.019
regulation of angiogenesis GO:0045765 81 0.019
negative regulation of protein modification by small protein conjugation or removal GO:1903321 20 0.019
defecation GO:0030421 1 0.019
ossification GO:0001503 216 0.019
extracellular matrix organization GO:0030198 147 0.019
ion transmembrane transport GO:0034220 361 0.018
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.018
regulation of stress fiber assembly GO:0051492 15 0.018
regulation of system process GO:0044057 200 0.018
positive regulation of intracellular transport GO:0032388 70 0.018
neurotransmitter secretion GO:0007269 62 0.018
regulation of protein ubiquitination GO:0031396 52 0.018
regulation of antibacterial peptide production GO:0002786 1 0.018
rho protein signal transduction GO:0007266 32 0.018
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.018
monocarboxylic acid metabolic process GO:0032787 191 0.018
protein localization to adherens junction GO:0071896 2 0.018
lymphocyte proliferation GO:0046651 164 0.018
defense response to other organism GO:0098542 197 0.018
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.018
posttranscriptional regulation of gene expression GO:0010608 155 0.017
meiotic cell cycle GO:0051321 122 0.017
digestive system development GO:0055123 200 0.017
mitotic cell cycle GO:0000278 195 0.017
myeloid cell homeostasis GO:0002262 114 0.017
regulation of atpase activity GO:0043462 9 0.017
regulation of synaptic plasticity GO:0048167 87 0.017
regulation of cytoplasmic transport GO:1903649 112 0.017
organelle localization GO:0051640 179 0.017
positive regulation of immune effector process GO:0002699 107 0.017
cellular metal ion homeostasis GO:0006875 151 0.017
lymphocyte differentiation GO:0030098 242 0.017
nucleoside phosphate metabolic process GO:0006753 338 0.017
innate immune response activating signal transduction GO:0002758 50 0.017
regulation of proteolysis GO:0030162 164 0.017
transmission of nerve impulse GO:0019226 76 0.017
striated muscle cell apoptotic process GO:0010658 12 0.016
lateral inhibition GO:0046331 1 0.016
response to inorganic substance GO:0010035 96 0.016
response to misfolded protein GO:0051788 5 0.016
ripoptosome assembly involved in necroptotic process GO:1901026 6 0.016
vesicle organization GO:0016050 60 0.016
oocyte anterior posterior axis specification GO:0007314 2 0.016
ribonucleoside monophosphate catabolic process GO:0009158 57 0.016
regulation of sphingolipid biosynthetic process GO:0090153 1 0.016
nuclear division GO:0000280 158 0.016
organelle fission GO:0048285 170 0.016
negative regulation of necroptotic process GO:0060546 9 0.016
regulation of myeloid leukocyte differentiation GO:0002761 58 0.016
response to calcium ion GO:0051592 20 0.016
protein import into nucleus GO:0006606 95 0.016
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 16 0.016
maternal determination of anterior posterior axis embryo GO:0008358 2 0.016
positive regulation of nik nf kappab signaling GO:1901224 7 0.016
developmental maturation GO:0021700 193 0.016
regulation of neuron differentiation GO:0045664 281 0.016
tumor necrosis factor production GO:0032640 50 0.016
regulation of ion transmembrane transporter activity GO:0032412 54 0.016
pattern recognition receptor signaling pathway GO:0002221 47 0.016
nucleoside metabolic process GO:0009116 246 0.015
ribonucleoprotein complex disassembly GO:0032988 3 0.015
regulation of nucleocytoplasmic transport GO:0046822 73 0.015
negative regulation of sterol transport GO:0032372 4 0.015
regulation of proteasomal protein catabolic process GO:0061136 46 0.015
interleukin 1 mediated signaling pathway GO:0070498 4 0.015
carbohydrate homeostasis GO:0033500 128 0.015
divalent inorganic cation transport GO:0072511 178 0.015
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.015
blood vessel morphogenesis GO:0048514 285 0.015
misfolded or incompletely synthesized protein catabolic process GO:0006515 4 0.015
establishment of protein localization to organelle GO:0072594 118 0.015
lymphocyte activation involved in immune response GO:0002285 93 0.015
cellular chemical homeostasis GO:0055082 215 0.015
cellular response to growth factor stimulus GO:0071363 197 0.015
generation of precursor metabolites and energy GO:0006091 103 0.015
detection of stimulus GO:0051606 84 0.015
negative regulation of protein catabolic process GO:0042177 36 0.015
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.015
skeletal system development GO:0001501 356 0.014
positive regulation of nucleoside metabolic process GO:0045979 91 0.014
protein oligomerization GO:0051259 67 0.014
positive regulation of growth GO:0045927 104 0.014
cellular response to amino acid stimulus GO:0071230 29 0.014
adult behavior GO:0030534 135 0.014
cytokine production involved in immune response GO:0002367 34 0.014
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.014
cytokine mediated signaling pathway GO:0019221 115 0.014
positive regulation of hydrolase activity GO:0051345 148 0.014
positive regulation of defense response to bacterium GO:1900426 1 0.014
plasma membrane organization GO:0007009 90 0.014
response to oxygen levels GO:0070482 62 0.014
positive regulation of cytokine production GO:0001819 174 0.014
embryonic epithelial tube formation GO:0001838 130 0.014
endocytosis GO:0006897 168 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.014
sensory perception GO:0007600 245 0.014
protein localization to plasma membrane GO:0072659 57 0.014
regulation of immunoglobulin production GO:0002637 42 0.014
response to monosaccharide GO:0034284 67 0.014
epithelial cell proliferation GO:0050673 174 0.014
regulation of homeostatic process GO:0032844 182 0.014
positive regulation of cell activation GO:0050867 158 0.014
positive regulation of nucleotide metabolic process GO:0045981 114 0.013
positive regulation of cytokine biosynthetic process GO:0042108 40 0.013
interleukin 13 secretion GO:0072611 2 0.013
cell cycle g1 s phase transition GO:0044843 57 0.013
regulation of metal ion transport GO:0010959 106 0.013
neuronal action potential GO:0019228 54 0.013
interleukin 8 production GO:0032637 4 0.013
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.013
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.013
cellular response to organonitrogen compound GO:0071417 145 0.013
calcium ion transport GO:0006816 159 0.013
learning or memory GO:0007611 148 0.013
myosin filament organization GO:0031033 3 0.013
multi multicellular organism process GO:0044706 109 0.013
leukocyte activation involved in immune response GO:0002366 126 0.013
peptidyl serine autophosphorylation GO:0036289 1 0.013
intermediate filament based process GO:0045103 27 0.013
regulation of transposition GO:0010528 2 0.013
osteoclast differentiation GO:0030316 62 0.013
early endosome to late endosome transport GO:0045022 2 0.013
cellular response to cadmium ion GO:0071276 3 0.013
erk1 and erk2 cascade GO:0070371 77 0.012
response to nitric oxide GO:0071731 4 0.012
protein localization to mitochondrion GO:0070585 15 0.012
protein hydroxylation GO:0018126 4 0.012
cognition GO:0050890 149 0.012
action potential GO:0001508 78 0.012
sequestering of metal ion GO:0051238 19 0.012
striated muscle tissue development GO:0014706 293 0.012
myd88 independent toll like receptor signaling pathway GO:0002756 3 0.012
inorganic cation transmembrane transport GO:0098662 207 0.012
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.012
nuclear transport GO:0051169 139 0.012
placenta development GO:0001890 140 0.012
cation transmembrane transport GO:0098655 266 0.012
keratinocyte differentiation GO:0030216 48 0.012

Hspa1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
muscular disease DOID:0080000 0 0.455
disease of anatomical entity DOID:7 0 0.455
musculoskeletal system disease DOID:17 0 0.455
muscle tissue disease DOID:66 0 0.142
heart disease DOID:114 0 0.084
cardiovascular system disease DOID:1287 0 0.084
nervous system disease DOID:863 0 0.078
central nervous system disease DOID:331 0 0.056
myopathy DOID:423 0 0.051
cardiomyopathy DOID:0050700 0 0.051
intrinsic cardiomyopathy DOID:0060036 0 0.051
neurodegenerative disease DOID:1289 0 0.039
skin disease DOID:37 0 0.024
integumentary system disease DOID:16 0 0.024
disease of cellular proliferation DOID:14566 0 0.018
immune system disease DOID:2914 0 0.015
hematopoietic system disease DOID:74 0 0.015
dilated cardiomyopathy DOID:12930 0 0.013