Mus musculus

139 known processes

Hspa8

heat shock protein 8

(Aliases: MGC102007,MGC118485,Hspa10,Hsc73,Hsc70,Hsc71,MGC106514,2410008N15Rik,Hsp73)

Hspa8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein refolding GO:0042026 1 1.000
Human Yeast
microtubule cytoskeleton organization GO:0000226 157 0.976
negative regulation of transposition GO:0010529 2 0.975
organelle assembly GO:0070925 177 0.952
pole plasm assembly GO:0007315 2 0.936
protein targeting to mitochondrion GO:0006626 6 0.915
Yeast
protein folding GO:0006457 28 0.903
regulation of transposition GO:0010528 2 0.864
microtubule based process GO:0007017 236 0.853
cellular response to interleukin 4 GO:0071353 21 0.849
chaperone mediated protein folding GO:0061077 10 0.810
oocyte axis specification GO:0007309 2 0.799
microtubule organizing center organization GO:0031023 28 0.793
cellular component assembly involved in morphogenesis GO:0010927 139 0.792
centrosome cycle GO:0007098 23 0.786
striated muscle myosin thick filament assembly GO:0071688 1 0.770
protein transmembrane transport GO:0071806 8 0.743
Yeast
positive regulation of cardiac muscle contraction GO:0060452 2 0.713
cell cell recognition GO:0009988 44 0.684
Mouse
myosin filament organization GO:0031033 3 0.681
oocyte anterior posterior axis specification GO:0007314 2 0.660
toxin transport GO:1901998 38 0.645
spindle assembly involved in mitosis GO:0090307 4 0.639
regionalization GO:0003002 337 0.608
nucleobase containing small molecule metabolic process GO:0055086 352 0.598
ribonucleotide metabolic process GO:0009259 291 0.587
single fertilization GO:0007338 82 0.565
Mouse
purine nucleotide metabolic process GO:0006163 302 0.559
protein localization to mitochondrion GO:0070585 15 0.540
Yeast
cellular response to topologically incorrect protein GO:0035967 25 0.540
Fly
centrosome organization GO:0051297 26 0.517
negative regulation of cellular protein metabolic process GO:0032269 247 0.486
sperm egg recognition GO:0035036 37 0.478
Mouse
mitotic spindle organization GO:0007052 10 0.476
nucleotide metabolic process GO:0009117 332 0.473
mitotic cell cycle GO:0000278 195 0.472
cellular response to cytokine stimulus GO:0071345 189 0.457
intracellular mrna localization GO:0008298 4 0.438
maternal determination of anterior posterior axis embryo GO:0008358 2 0.437
mitochondrion organization GO:0007005 134 0.419
Yeast
ribose phosphate metabolic process GO:0019693 291 0.419
regulation of kinase activity GO:0043549 249 0.416
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.415
response to interleukin 4 GO:0070670 23 0.413
myosin filament assembly GO:0031034 2 0.408
regulation of establishment of protein localization GO:0070201 181 0.405
oocyte construction GO:0007308 2 0.404
regulation of transferase activity GO:0051338 263 0.396
cellular protein complex assembly GO:0043623 116 0.395
cell recognition GO:0008037 83 0.392
Mouse Fly
de novo protein folding GO:0006458 9 0.382
response to heat GO:0009408 27 0.377
Yeast
purine nucleoside metabolic process GO:0042278 241 0.373
telomere maintenance GO:0000723 19 0.368
circadian sleep wake cycle GO:0042745 5 0.361
positive regulation of apoptotic process GO:0043065 217 0.358
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.356
spindle assembly GO:0051225 13 0.354
proteasome assembly GO:0043248 1 0.354
binding of sperm to zona pellucida GO:0007339 34 0.352
Mouse
establishment of protein localization to mitochondrion GO:0072655 11 0.347
Yeast
cilium morphogenesis GO:0060271 102 0.340
dna metabolic process GO:0006259 303 0.338
chromatin modification GO:0016568 187 0.328
intermediate filament cytoskeleton organization GO:0045104 26 0.314
nucleoside triphosphate catabolic process GO:0009143 205 0.310
anatomical structure homeostasis GO:0060249 145 0.309
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.299
genitalia development GO:0048806 37 0.298
nucleoside monophosphate catabolic process GO:0009125 59 0.295
nucleoside phosphate metabolic process GO:0006753 338 0.295
development of primary sexual characteristics GO:0045137 143 0.287
gonad development GO:0008406 141 0.284
fertilization GO:0009566 127 0.277
Mouse
germ cell development GO:0007281 185 0.273
muscle cell apoptotic process GO:0010657 18 0.267
regulation of protein import into nucleus translocation GO:0033158 2 0.265
cellular response to heat GO:0034605 15 0.265
Yeast
regulation of cellular response to stress GO:0080135 159 0.265
spermatogenesis GO:0007283 284 0.263
muscle cell differentiation GO:0042692 261 0.261
aromatic compound catabolic process GO:0019439 286 0.259
nucleoside metabolic process GO:0009116 246 0.259
regulation of protein kinase activity GO:0045859 232 0.256
heterocycle catabolic process GO:0046700 280 0.243
nucleotide catabolic process GO:0009166 217 0.234
urogenital system development GO:0001655 261 0.229
centrosome duplication GO:0051298 16 0.228
protein localization to organelle GO:0033365 185 0.228
Yeast
nuclear division GO:0000280 158 0.227
nucleoside triphosphate metabolic process GO:0009141 230 0.226
positive regulation of growth GO:0045927 104 0.217
positive regulation of striated muscle contraction GO:0045989 3 0.216
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.215
ribonucleoside metabolic process GO:0009119 245 0.212
mitotic cell cycle process GO:1903047 159 0.211
positive regulation of transferase activity GO:0051347 167 0.205
regulation of stress activated mapk cascade GO:0032872 69 0.203
nucleoside phosphate catabolic process GO:1901292 222 0.199
male gamete generation GO:0048232 285 0.198
regulation of protein transport GO:0051223 163 0.197
regulation of protein serine threonine kinase activity GO:0071900 157 0.196
cell type specific apoptotic process GO:0097285 268 0.194
multicellular organismal aging GO:0010259 24 0.192
cellular nitrogen compound catabolic process GO:0044270 280 0.192
purine ribonucleotide metabolic process GO:0009150 290 0.191
regulation of intracellular transport GO:0032386 159 0.189
positive regulation of cell death GO:0010942 224 0.187
response to temperature stimulus GO:0009266 55 0.186
Yeast
establishment of organelle localization GO:0051656 122 0.184
ribonucleoside triphosphate catabolic process GO:0009203 199 0.184
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.179
meiotic nuclear division GO:0007126 115 0.176
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.176
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.173
atp metabolic process GO:0046034 75 0.168
organelle fission GO:0048285 170 0.167
telomere maintenance via telomerase GO:0007004 1 0.166
intracellular protein transport GO:0006886 204 0.164
Yeast
purine nucleotide catabolic process GO:0006195 211 0.162
posttranscriptional regulation of gene expression GO:0010608 155 0.161
Fly
rna dependent dna replication GO:0006278 3 0.158
rna localization GO:0006403 23 0.158
retina homeostasis GO:0001895 23 0.156
glycosyl compound metabolic process GO:1901657 246 0.155
purine nucleoside catabolic process GO:0006152 205 0.155
regulation of cysteine type endopeptidase activity GO:2000116 65 0.154
organic cyclic compound catabolic process GO:1901361 295 0.151
ribonucleoside catabolic process GO:0042454 206 0.151
positive regulation of protein import into nucleus translocation GO:0033160 1 0.148
positive regulation of dna replication GO:0045740 9 0.146
positive regulation of protein phosphorylation GO:0001934 242 0.145
skeletal muscle thin filament assembly GO:0030240 2 0.138
cardiac muscle contraction GO:0060048 32 0.138
regulation of organelle organization GO:0033043 289 0.137
protein modification by small protein conjugation or removal GO:0070647 207 0.135
circadian rhythm GO:0007623 114 0.135
purine ribonucleotide catabolic process GO:0009154 208 0.134
transmembrane transport GO:0055085 412 0.133
Yeast
actin cytoskeleton organization GO:0030036 220 0.129
dna replication GO:0006260 52 0.128
receptor mediated endocytosis GO:0006898 51 0.128
oocyte differentiation GO:0009994 35 0.127
regulation of protein localization GO:0032880 231 0.127
spindle organization GO:0007051 28 0.127
regulation of reactive oxygen species metabolic process GO:2000377 40 0.126
protein ubiquitination GO:0016567 171 0.124
organonitrogen compound catabolic process GO:1901565 264 0.123
regulation of cell cycle GO:0051726 281 0.122
reactive oxygen species metabolic process GO:0072593 84 0.121
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.120
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.119
camera type eye development GO:0043010 266 0.119
glycosyl compound catabolic process GO:1901658 206 0.117
positive regulation of kinase activity GO:0033674 155 0.116
purine containing compound catabolic process GO:0072523 213 0.114
regulation of protein binding GO:0043393 60 0.113
renal system development GO:0072001 225 0.113
meiotic cell cycle GO:0051321 122 0.112
cytoplasmic transport GO:0016482 234 0.112
Yeast
mitochondrial transport GO:0006839 36 0.112
Yeast
negative regulation of protein metabolic process GO:0051248 282 0.110
organelle disassembly GO:1903008 2 0.109
Yeast
positive regulation of programmed cell death GO:0043068 218 0.109
regulation of epidermal cell division GO:0010482 3 0.109
female gamete generation GO:0007292 74 0.108
negative regulation of inclusion body assembly GO:0090084 1 0.108
apoptotic signaling pathway GO:0097190 306 0.108
protein modification by small protein conjugation GO:0032446 187 0.108
nuclear transport GO:0051169 139 0.107
Yeast
regulation of intracellular protein transport GO:0033157 82 0.107
response to topologically incorrect protein GO:0035966 25 0.105
Fly
oogenesis GO:0048477 56 0.105
positive regulation of hydrolase activity GO:0051345 148 0.105
actomyosin structure organization GO:0031032 56 0.105
establishment of protein localization to organelle GO:0072594 118 0.105
Yeast
actin filament organization GO:0007015 113 0.104
regulation of cytoplasmic transport GO:1903649 112 0.104
negative regulation of molecular function GO:0044092 258 0.101
response to oxidative stress GO:0006979 123 0.101
ribonucleoside monophosphate catabolic process GO:0009158 57 0.100
reactive nitrogen species metabolic process GO:2001057 0 0.099
atp catabolic process GO:0006200 55 0.099
regulation of cardiac muscle contraction GO:0055117 21 0.098
thermosensory behavior GO:0040040 1 0.098
response to organic cyclic compound GO:0014070 198 0.098
macromolecule catabolic process GO:0009057 281 0.092
Yeast
purine ribonucleoside catabolic process GO:0046130 205 0.092
circadian behavior GO:0048512 13 0.092
negative regulation of jun kinase activity GO:0043508 9 0.091
organelle localization GO:0051640 179 0.091
covalent chromatin modification GO:0016569 163 0.090
response to calcium ion GO:0051592 20 0.089
photoreceptor cell development GO:0042461 40 0.088
purine containing compound metabolic process GO:0072521 311 0.088
regulation of protein ubiquitination GO:0031396 52 0.087
chromatin organization GO:0006325 206 0.087
body morphogenesis GO:0010171 45 0.087
regulation of nucleocytoplasmic transport GO:0046822 73 0.086
inclusion body assembly GO:0070841 3 0.085
skeletal muscle myosin thick filament assembly GO:0030241 1 0.085
embryonic organ morphogenesis GO:0048562 276 0.085
kidney development GO:0001822 213 0.084
response to inorganic substance GO:0010035 96 0.084
response to metal ion GO:0010038 47 0.083
endocytosis GO:0006897 168 0.082
purine nucleoside monophosphate metabolic process GO:0009126 81 0.080
response to uv a GO:0070141 1 0.080
regulation of neuron apoptotic process GO:0043523 122 0.079
positive regulation of protein kinase activity GO:0045860 144 0.078
purine ribonucleoside metabolic process GO:0046128 241 0.078
purine nucleoside monophosphate catabolic process GO:0009128 58 0.078
regulation of muscle system process GO:0090257 80 0.077
regulation of peptidase activity GO:0052547 96 0.077
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.077
striated muscle cell development GO:0055002 125 0.075
cellular response to dna damage stimulus GO:0006974 207 0.074
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.071
regulation of circadian rhythm GO:0042752 58 0.071
negative regulation of protein modification by small protein conjugation or removal GO:1903321 20 0.070
single organism nuclear import GO:1902593 95 0.070
Yeast
oocyte development GO:0048599 33 0.070
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.069
muscle system process GO:0003012 141 0.069
establishment of protein localization to membrane GO:0090150 54 0.068
Yeast
regulation of cellular component biogenesis GO:0044087 181 0.068
response to cold GO:0009409 19 0.067
negative regulation of protein modification process GO:0031400 163 0.066
nucleoside catabolic process GO:0009164 206 0.066
positive regulation of protein transport GO:0051222 93 0.065
reactive oxygen species biosynthetic process GO:1903409 8 0.065
positive regulation of nitric oxide biosynthetic process GO:0045429 14 0.064
digestive tract morphogenesis GO:0048546 147 0.064
response to organonitrogen compound GO:0010243 246 0.063
regulation of cell size GO:0008361 72 0.063
cell maturation GO:0048469 127 0.063
regulation of protein import into nucleus GO:0042306 52 0.063
developmental maturation GO:0021700 193 0.062
cytoplasmic microtubule organization GO:0031122 14 0.061
positive regulation of protein modification process GO:0031401 299 0.060
protein localization to nucleus GO:0034504 121 0.059
Yeast
positive regulation of intracellular transport GO:0032388 70 0.058
regulation of ion transport GO:0043269 215 0.058
regulation of endopeptidase activity GO:0052548 89 0.058
mrna 3 end processing GO:0031124 16 0.057
regulation of ubiquitin protein ligase activity involved in mitotic cell cycle GO:0051439 1 0.057
keratinocyte development GO:0003334 10 0.056
negative regulation of cellular component organization GO:0051129 194 0.056
Human
ribonucleotide catabolic process GO:0009261 208 0.056
ribonucleoside triphosphate metabolic process GO:0009199 220 0.054
intrinsic apoptotic signaling pathway GO:0097193 132 0.054
regulation of chromosome organization GO:0033044 83 0.053
striated muscle contraction GO:0006941 45 0.053
protein import GO:0017038 101 0.053
Yeast
negative regulation of phosphorylation GO:0042326 166 0.053
positive regulation of organelle organization GO:0010638 128 0.052
organophosphate catabolic process GO:0046434 232 0.052
response to radiation GO:0009314 165 0.052
nuclear import GO:0051170 95 0.052
Yeast
intracellular steroid hormone receptor signaling pathway GO:0030518 29 0.051
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.051
embryonic heart tube morphogenesis GO:0003143 51 0.050
neuron apoptotic process GO:0051402 142 0.050
nucleoside monophosphate metabolic process GO:0009123 85 0.049
negative regulation of phosphorus metabolic process GO:0010563 184 0.049
regulation of cell projection assembly GO:0060491 38 0.049
sperm motility GO:0030317 47 0.049
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.049
response to osmotic stress GO:0006970 21 0.049
response to light stimulus GO:0009416 135 0.049
positive regulation of protein modification by small protein conjugation or removal GO:1903322 30 0.049
muscle contraction GO:0006936 101 0.048
negative regulation of cell proliferation GO:0008285 296 0.048
positive regulation of intracellular protein transport GO:0090316 42 0.047
regulation of cytoskeleton organization GO:0051493 122 0.047
rhythmic process GO:0048511 174 0.047
cellular macromolecule catabolic process GO:0044265 206 0.047
Yeast
telomere maintenance via telomere lengthening GO:0010833 4 0.047
carbohydrate derivative catabolic process GO:1901136 231 0.046
nitric oxide metabolic process GO:0046209 25 0.046
histone modification GO:0016570 159 0.046
purine nucleoside triphosphate catabolic process GO:0009146 203 0.046
regulation of anatomical structure size GO:0090066 178 0.045
microtubule based movement GO:0007018 84 0.045
cellular response to oxidative stress GO:0034599 76 0.045
negative regulation of transferase activity GO:0051348 85 0.045
segmentation GO:0035282 93 0.045
regulation of protein targeting GO:1903533 61 0.045
axon cargo transport GO:0008088 33 0.045
ribonucleoside monophosphate metabolic process GO:0009161 80 0.045
intermediate filament organization GO:0045109 15 0.044
protein targeting to er GO:0045047 2 0.044
Yeast
hindbrain development GO:0030902 128 0.043
positive regulation of protein import into nucleus GO:0042307 26 0.042
regulation of hydrolase activity GO:0051336 246 0.042
microtubule based transport GO:0010970 50 0.042
regulation of binding GO:0051098 111 0.042
mapk cascade GO:0000165 281 0.042
regulation of dna replication GO:0006275 17 0.041
regulation of lamellipodium assembly GO:0010591 3 0.041
cellularization GO:0007349 1 0.041
multicellular organismal water homeostasis GO:0050891 23 0.041
mitotic nuclear division GO:0007067 48 0.040
cytoskeleton dependent intracellular transport GO:0030705 50 0.039
positive regulation of lamellipodium assembly GO:0010592 2 0.039
protein localization to membrane GO:0072657 108 0.039
Yeast
placenta development GO:0001890 140 0.039
regeneration GO:0031099 38 0.039
cell growth GO:0016049 130 0.038
regulation of transporter activity GO:0032409 57 0.038
protein targeting GO:0006605 143 0.038
Yeast
positive regulation of protein localization to nucleus GO:1900182 30 0.038
endoplasmic reticulum unfolded protein response GO:0030968 19 0.037
stress activated mapk cascade GO:0051403 80 0.037
er nucleus signaling pathway GO:0006984 27 0.037
positive regulation of nucleocytoplasmic transport GO:0046824 30 0.037
modification dependent macromolecule catabolic process GO:0043632 133 0.037
regulation of protein localization to nucleus GO:1900180 60 0.037
regulation of cellular component size GO:0032535 121 0.037
cardiac muscle cell apoptotic process GO:0010659 10 0.036
regulation of cell projection organization GO:0031344 206 0.036
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.036
regulation of apoptotic signaling pathway GO:2001233 197 0.036
negative regulation of protein phosphorylation GO:0001933 126 0.036
negative regulation of neuron death GO:1901215 98 0.035
3 utr mediated mrna stabilization GO:0070935 2 0.035
protein import into nucleus GO:0006606 95 0.035
Yeast
negative regulation of neuron apoptotic process GO:0043524 92 0.035
purine nucleoside triphosphate metabolic process GO:0009144 226 0.035
multicellular organism growth GO:0035264 161 0.035
cation transmembrane transport GO:0098655 266 0.034
macromolecular complex disassembly GO:0032984 43 0.034
substantia nigra development GO:0021762 2 0.034
meiotic cell cycle process GO:1903046 77 0.034
microtubule polymerization or depolymerization GO:0031109 26 0.033
cilium assembly GO:0042384 81 0.033
muscle tissue development GO:0060537 308 0.033
response to unfolded protein GO:0006986 21 0.033
nucleic acid transport GO:0050657 18 0.033
ras protein signal transduction GO:0007265 77 0.033
regulation of inclusion body assembly GO:0090083 1 0.033
small gtpase mediated signal transduction GO:0007264 97 0.032
regulation of ion transmembrane transport GO:0034765 119 0.032
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.032
nitric oxide biosynthetic process GO:0006809 25 0.032
maintenance of location GO:0051235 89 0.031
sleep GO:0030431 7 0.031
regulation of microtubule cytoskeleton organization GO:0070507 37 0.031
respiratory system development GO:0060541 190 0.031
cardiac muscle cell differentiation GO:0055007 69 0.031
organic acid biosynthetic process GO:0016053 86 0.031
regulation of ion transmembrane transporter activity GO:0032412 54 0.031
intermediate filament based process GO:0045103 27 0.031
neuron death GO:0070997 154 0.031
response to peptide GO:1901652 136 0.031
rhythmic behavior GO:0007622 15 0.030
regulation of nucleotide metabolic process GO:0006140 169 0.030
sensory organ morphogenesis GO:0090596 242 0.030
locomotory behavior GO:0007626 195 0.029
regulation of exit from mitosis GO:0007096 1 0.029
blood circulation GO:0008015 195 0.029
skeletal myofibril assembly GO:0014866 4 0.029
cellular ketone metabolic process GO:0042180 84 0.028
detection of stimulus GO:0051606 84 0.028
negative regulation of cell development GO:0010721 169 0.028
spermatid development GO:0007286 108 0.028
actin filament based movement GO:0030048 23 0.028
regulation of jnk cascade GO:0046328 62 0.028
proteasomal protein catabolic process GO:0010498 98 0.027
negative regulation of protein ubiquitination GO:0031397 19 0.027
aggresome assembly GO:0070842 2 0.027
positive regulation of cellular component biogenesis GO:0044089 94 0.027
regulation of circadian sleep wake cycle GO:0042749 3 0.027
positive regulation of muscle contraction GO:0045933 10 0.027
protein polymerization GO:0051258 57 0.026
regulation of jun kinase activity GO:0043506 40 0.026
neuron migration GO:0001764 122 0.026
centrosome separation GO:0051299 4 0.026
nucleus localization GO:0051647 20 0.026
regulation of nitric oxide biosynthetic process GO:0045428 18 0.026
synaptic transmission GO:0007268 329 0.026
Fly
positive regulation of cytoplasmic transport GO:1903651 40 0.025
positive regulation of binding GO:0051099 49 0.025
skeletal muscle organ development GO:0060538 163 0.025
male courtship behavior GO:0008049 2 0.025
circulatory system process GO:0003013 197 0.025
mitotic cytokinesis GO:0000281 4 0.024
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 19 0.024
regulation of homeostatic process GO:0032844 182 0.024
blastoderm segmentation GO:0007350 13 0.024
dendrite development GO:0016358 115 0.024
regulation of muscle contraction GO:0006937 49 0.024
regulation of epidermal cell differentiation GO:0045604 21 0.024
oxidation reduction process GO:0055114 342 0.024
regulation of mapk cascade GO:0043408 248 0.024
epithelial cell development GO:0002064 159 0.023
cellular response to antibiotic GO:0071236 4 0.023
negative regulation of apoptotic signaling pathway GO:2001234 104 0.023
mitochondrion degradation GO:0000422 3 0.023
regulation of cell cycle process GO:0010564 160 0.023
epidermis development GO:0008544 187 0.023
regulation of cellular catabolic process GO:0031329 242 0.023
negative regulation of jnk cascade GO:0046329 12 0.023
regulation of metal ion transport GO:0010959 106 0.022
regulation of body fluid levels GO:0050878 162 0.022
determination of left right symmetry GO:0007368 80 0.022
regulation of neuron death GO:1901214 134 0.022
cytoplasm organization GO:0007028 8 0.022
striated muscle cell apoptotic process GO:0010658 12 0.022
pore complex assembly GO:0046931 3 0.022
monocarboxylic acid metabolic process GO:0032787 191 0.022
carbohydrate metabolic process GO:0005975 230 0.022
regulation of cell motility GO:2000145 236 0.022
positive regulation of proteolysis GO:0045862 85 0.021
negative regulation of kinase activity GO:0033673 81 0.021
androgen receptor signaling pathway GO:0030521 8 0.021
positive regulation of protein ubiquitination GO:0031398 27 0.021
multicellular organismal homeostasis GO:0048871 164 0.021
epithelial cell proliferation GO:0050673 174 0.021
regulation of microtubule based process GO:0032886 52 0.021
intracellular receptor signaling pathway GO:0030522 74 0.021
wnt signaling pathway GO:0016055 188 0.021
cyclic nucleotide metabolic process GO:0009187 59 0.021
midbrain development GO:0030901 35 0.021
striated muscle tissue development GO:0014706 293 0.021
lung development GO:0030324 164 0.020
digestive system development GO:0055123 200 0.020
cellular glucan metabolic process GO:0006073 32 0.020
response to corticosterone GO:0051412 1 0.020
male sex differentiation GO:0046661 109 0.020
positive regulation of mapk cascade GO:0043410 170 0.020
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.020
lymphocyte proliferation GO:0046651 164 0.020
cellular amino acid biosynthetic process GO:0008652 22 0.020
microtubule polymerization GO:0046785 12 0.019
tripartite regional subdivision GO:0007351 9 0.019
defecation GO:0030421 1 0.019
response to estrogen GO:0043627 24 0.019
cellular modified amino acid metabolic process GO:0006575 63 0.019
regulation of cell shape GO:0008360 39 0.019
cerebellum development GO:0021549 77 0.019
cellular response to lipid GO:0071396 145 0.019
energy derivation by oxidation of organic compounds GO:0015980 77 0.019
posttranscriptional gene silencing GO:0016441 10 0.019
Fly
positive regulation of peptidase activity GO:0010952 49 0.019
positive regulation of chromosome organization GO:2001252 33 0.019
cellular protein catabolic process GO:0044257 155 0.019
Yeast
regulation of phosphoprotein phosphatase activity GO:0043666 3 0.019
protein depolymerization GO:0051261 34 0.019
nucleobase containing compound transport GO:0015931 27 0.019
keratinocyte differentiation GO:0030216 48 0.019
regulation of stem cell proliferation GO:0072091 78 0.019
cation transport GO:0006812 399 0.019
peptidyl amino acid modification GO:0018193 336 0.019
negative regulation of ubiquitin protein transferase activity GO:0051444 3 0.018
chemotaxis GO:0006935 247 0.018
Fly
positive regulation of cell projection organization GO:0031346 95 0.018
stem cell proliferation GO:0072089 117 0.018
myofibril assembly GO:0030239 34 0.018
metencephalon development GO:0022037 89 0.018
endomembrane system organization GO:0010256 147 0.018
carboxylic acid biosynthetic process GO:0046394 86 0.018
ribonucleoprotein complex subunit organization GO:0071826 28 0.018
Yeast
regulation of epithelial cell proliferation GO:0050678 141 0.017
nitrogen compound transport GO:0071705 271 0.017
regulation of protein export from nucleus GO:0046825 11 0.017
calcium ion transmembrane transport GO:0070588 85 0.017
multicellular organismal reproductive behavior GO:0033057 23 0.017
positive regulation of interferon alpha production GO:0032727 4 0.017
multi multicellular organism process GO:0044706 109 0.017
regulation of purine nucleotide metabolic process GO:1900542 169 0.017
photoreceptor cell differentiation GO:0046530 52 0.017
response to nutrient levels GO:0031667 109 0.017
response to peptide hormone GO:0043434 127 0.016
response to extracellular stimulus GO:0009991 127 0.016
mrna splicing via spliceosome GO:0000398 43 0.016
positive regulation of epidermis development GO:0045684 13 0.016
regulation of cell growth GO:0001558 91 0.016
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.016
positive regulation of endopeptidase activity GO:0010950 43 0.016
carbohydrate derivative biosynthetic process GO:1901137 183 0.016
zymogen activation GO:0031638 41 0.016
neurofilament cytoskeleton organization GO:0060052 10 0.016
establishment of spindle localization GO:0051293 19 0.016

Hspa8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.340
nervous system disease DOID:863 0 0.340
central nervous system disease DOID:331 0 0.299
nephronophthisis DOID:12712 0 0.082
neurodegenerative disease DOID:1289 0 0.043
physical disorder DOID:0080015 0 0.027
joubert syndrome DOID:0050777 0 0.024
disease of cellular proliferation DOID:14566 0 0.020
musculoskeletal system disease DOID:17 0 0.019
cancer DOID:162 0 0.018
organ system cancer DOID:0050686 0 0.018