Mus musculus

0 known processes

Iars

isoleucine-tRNA synthetase

(Aliases: 2510016L12Rik,ILRS,E430001P04Rik,AI327140,AU044614)

Iars biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
amino acid activation GO:0043038 1 0.578
Yeast
translation GO:0006412 93 0.526
Yeast
trna aminoacylation for protein translation GO:0006418 1 0.476
Yeast
cellular amino acid metabolic process GO:0006520 103 0.470
Yeast
trna aminoacylation GO:0043039 1 0.256
Yeast
posttranscriptional regulation of gene expression GO:0010608 155 0.160
trna metabolic process GO:0006399 11 0.146
Yeast
neuron apoptotic process GO:0051402 142 0.145
regulation of translation GO:0006417 71 0.138
regulation of organelle organization GO:0033043 289 0.078
folic acid containing compound metabolic process GO:0006760 3 0.069
nucleobase containing small molecule metabolic process GO:0055086 352 0.068
ribonucleoprotein complex disassembly GO:0032988 3 0.067
protein import into nucleus GO:0006606 95 0.064
cellular amine metabolic process GO:0044106 44 0.060
organelle disassembly GO:1903008 2 0.059
amine metabolic process GO:0009308 45 0.059
response to oxidative stress GO:0006979 123 0.054
cytoplasmic transport GO:0016482 234 0.053
establishment of organelle localization GO:0051656 122 0.047
macromolecule methylation GO:0043414 120 0.047
neuron death GO:0070997 154 0.041
organelle localization GO:0051640 179 0.039
cellular protein complex assembly GO:0043623 116 0.036
negative regulation of neuron death GO:1901215 98 0.035
hematopoietic progenitor cell differentiation GO:0002244 143 0.032
negative regulation of cellular protein metabolic process GO:0032269 247 0.031
cellular nitrogen compound catabolic process GO:0044270 280 0.031
cellular response to cytokine stimulus GO:0071345 189 0.030
methylation GO:0032259 134 0.030
metaphase plate congression GO:0051310 2 0.029
nucleocytoplasmic transport GO:0006913 139 0.029
regulation of neuron apoptotic process GO:0043523 122 0.028
establishment of protein localization to organelle GO:0072594 118 0.027
regulation of protein localization GO:0032880 231 0.027
membrane organization GO:0061024 245 0.027
protein import GO:0017038 101 0.026
circadian rhythm GO:0007623 114 0.026
multicellular organismal homeostasis GO:0048871 164 0.026
regulation of cellular amine metabolic process GO:0033238 20 0.025
nuclear transport GO:0051169 139 0.025
regulation of neuron death GO:1901214 134 0.024
negative regulation of neuron apoptotic process GO:0043524 92 0.024
apoptotic signaling pathway GO:0097190 306 0.024
carbohydrate derivative catabolic process GO:1901136 231 0.023
epidermis development GO:0008544 187 0.023
regulation of cell cycle GO:0051726 281 0.023
mitochondrial translation GO:0032543 4 0.022
organophosphate biosynthetic process GO:0090407 122 0.022
regulation of exit from mitosis GO:0007096 1 0.022
regulation of cellular component size GO:0032535 121 0.022
negative regulation of dna replication GO:0008156 4 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.021
regulation of mitochondrion organization GO:0010821 27 0.021
nucleoside phosphate metabolic process GO:0006753 338 0.021
mitochondrion organization GO:0007005 134 0.021
regulation of cellular amino acid metabolic process GO:0006521 5 0.021
purine nucleoside triphosphate metabolic process GO:0009144 226 0.020
organic cyclic compound catabolic process GO:1901361 295 0.020
regulation of cytoskeleton organization GO:0051493 122 0.020
regulation of cellular ketone metabolic process GO:0010565 66 0.019
positive regulation of protein transport GO:0051222 93 0.019
developmental growth involved in morphogenesis GO:0060560 138 0.019
ribosome biogenesis GO:0042254 20 0.019
leukocyte proliferation GO:0070661 172 0.018
nucleotide biosynthetic process GO:0009165 78 0.018
endocytosis GO:0006897 168 0.018
leukocyte differentiation GO:0002521 342 0.018
wound healing GO:0042060 157 0.018
purine nucleoside catabolic process GO:0006152 205 0.018
t cell proliferation GO:0042098 120 0.018
protein targeting GO:0006605 143 0.018
neuromuscular process GO:0050905 99 0.017
organonitrogen compound biosynthetic process GO:1901566 192 0.017
single organism nuclear import GO:1902593 95 0.017
innate immune response GO:0045087 157 0.017
cell growth GO:0016049 130 0.017
gonad development GO:0008406 141 0.017
regulation of establishment of protein localization GO:0070201 181 0.017
actin cytoskeleton organization GO:0030036 220 0.017
ribose phosphate metabolic process GO:0019693 291 0.017
protein localization to nucleus GO:0034504 121 0.017
response to amino acid GO:0043200 37 0.017
response to acid chemical GO:0001101 111 0.016
positive regulation of cellular amine metabolic process GO:0033240 5 0.016
myeloid leukocyte differentiation GO:0002573 119 0.016
purine ribonucleotide catabolic process GO:0009154 208 0.016
actin filament organization GO:0007015 113 0.016
regulation of hydrolase activity GO:0051336 246 0.016
coenzyme metabolic process GO:0006732 52 0.016
regulation of protein binding GO:0043393 60 0.016
ribonucleoside metabolic process GO:0009119 245 0.016
regulation of protein transport GO:0051223 163 0.015
ribose phosphate biosynthetic process GO:0046390 59 0.015
nucleotide metabolic process GO:0009117 332 0.015
purine ribonucleotide metabolic process GO:0009150 290 0.015
positive regulation of cell activation GO:0050867 158 0.015
cation transmembrane transport GO:0098655 266 0.015
t cell activation GO:0042110 289 0.015
germ cell development GO:0007281 185 0.014
negative regulation of cell proliferation GO:0008285 296 0.014
nls bearing protein import into nucleus GO:0006607 2 0.014
nucleoside phosphate biosynthetic process GO:1901293 79 0.014
response to organonitrogen compound GO:0010243 246 0.014
rna processing GO:0006396 105 0.014
nuclear import GO:0051170 95 0.014
regulation of protein localization to nucleus GO:1900180 60 0.014
response to reactive oxygen species GO:0000302 56 0.014
ossification GO:0001503 216 0.014
Human
regulation of intracellular transport GO:0032386 159 0.014
pteridine containing compound metabolic process GO:0042558 5 0.014
cellular response to organonitrogen compound GO:0071417 145 0.014
gene silencing by rna GO:0031047 19 0.014
muscle tissue development GO:0060537 308 0.014
positive regulation of hydrolase activity GO:0051345 148 0.013
negative regulation of molecular function GO:0044092 258 0.013
cellular protein complex disassembly GO:0043624 36 0.013
ribonucleoside catabolic process GO:0042454 206 0.013
regulation of intracellular protein transport GO:0033157 82 0.013
negative regulation of protein metabolic process GO:0051248 282 0.013
cellular response to oxidative stress GO:0034599 76 0.013
nuclear division GO:0000280 158 0.013
ras protein signal transduction GO:0007265 77 0.013
forebrain development GO:0030900 302 0.013
cellular ketone metabolic process GO:0042180 84 0.013
organonitrogen compound catabolic process GO:1901565 264 0.013
microtubule based process GO:0007017 236 0.013
small gtpase mediated signal transduction GO:0007264 97 0.013
cell type specific apoptotic process GO:0097285 268 0.012
cellular response to amino acid stimulus GO:0071230 29 0.012
nucleoside triphosphate metabolic process GO:0009141 230 0.012
positive regulation of protein localization to nucleus GO:1900182 30 0.012
maintenance of location GO:0051235 89 0.012
positive regulation of translation GO:0045727 19 0.012
glycosyl compound metabolic process GO:1901657 246 0.011
secretory granule organization GO:0033363 20 0.011
nucleoside catabolic process GO:0009164 206 0.011
regulation of neuron differentiation GO:0045664 281 0.011
intrinsic apoptotic signaling pathway GO:0097193 132 0.011
maturation of ssu rrna GO:0030490 1 0.011
divalent inorganic cation transport GO:0072511 178 0.011
regulation of secretion by cell GO:1903530 249 0.011
regulation of cellular component biogenesis GO:0044087 181 0.011
mitotic cell cycle process GO:1903047 159 0.011
positive regulation of intracellular protein transport GO:0090316 42 0.011
purine containing compound metabolic process GO:0072521 311 0.011
regulation of membrane potential GO:0042391 192 0.011
response to inorganic substance GO:0010035 96 0.011
heterocycle catabolic process GO:0046700 280 0.011
protein alkylation GO:0008213 81 0.011
skin development GO:0043588 220 0.011
lymphocyte proliferation GO:0046651 164 0.011
response to endoplasmic reticulum stress GO:0034976 53 0.011
nucleus organization GO:0006997 45 0.010
dna damage response signal transduction by p53 class mediator GO:0030330 19 0.010
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.010
regulation of cell motility GO:2000145 236 0.010
regulation of tor signaling GO:0032006 17 0.010
purine nucleoside metabolic process GO:0042278 241 0.010
locomotory behavior GO:0007626 195 0.010
sensory perception GO:0007600 245 0.010
molting cycle GO:0042303 90 0.010
ribonucleotide catabolic process GO:0009261 208 0.010

Iars disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.889
nervous system disease DOID:863 0 0.889
neuropathy DOID:870 0 0.889
neuromuscular disease DOID:440 0 0.256
charcot marie tooth disease DOID:10595 0 0.112
charcot marie tooth disease type 2 DOID:0050539 0 0.049
central nervous system disease DOID:331 0 0.017
neurodegenerative disease DOID:1289 0 0.017
sensory system disease DOID:0050155 0 0.015