Mus musculus

0 known processes

Idh3a

isocitrate dehydrogenase 3 (NAD+) alpha

(Aliases: 1110003P10Rik,AI316514,AA407078,1500012E04Rik)

Idh3a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mitochondrion organization GO:0007005 134 0.480
thioester biosynthetic process GO:0035384 7 0.367
mitochondrial calcium ion homeostasis GO:0051560 7 0.282
acyl coa biosynthetic process GO:0071616 7 0.280
oxidation reduction process GO:0055114 342 0.265
Yeast Rat
coenzyme metabolic process GO:0006732 52 0.247
Rat
acetyl coa biosynthetic process from pyruvate GO:0006086 3 0.238
acetyl coa biosynthetic process GO:0006085 5 0.212
nucleobase containing small molecule metabolic process GO:0055086 352 0.204
Rat
citrate metabolic process GO:0006101 3 0.199
coenzyme biosynthetic process GO:0009108 23 0.197
purine ribonucleotide metabolic process GO:0009150 290 0.179
mitochondrial translation GO:0032543 4 0.176
cellular respiration GO:0045333 38 0.168
Rat
purine nucleotide metabolic process GO:0006163 302 0.152
ribonucleotide metabolic process GO:0009259 291 0.148
glycosyl compound metabolic process GO:1901657 246 0.141
cellular homeostasis GO:0019725 240 0.130
atp metabolic process GO:0046034 75 0.120
nucleoside phosphate metabolic process GO:0006753 338 0.110
Rat
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.109
ion transmembrane transport GO:0034220 361 0.109
generation of precursor metabolites and energy GO:0006091 103 0.104
Rat
transmembrane transport GO:0055085 412 0.098
cellular ion homeostasis GO:0006873 165 0.094
energy derivation by oxidation of organic compounds GO:0015980 77 0.088
Rat
cellular chemical homeostasis GO:0055082 215 0.088
ribonucleoside monophosphate metabolic process GO:0009161 80 0.087
cation transport GO:0006812 399 0.082
purine containing compound metabolic process GO:0072521 311 0.081
purine ribonucleoside metabolic process GO:0046128 241 0.078
sulfur compound biosynthetic process GO:0044272 37 0.078
cellular metal ion homeostasis GO:0006875 151 0.074
metal ion homeostasis GO:0055065 189 0.072
cofactor transport GO:0051181 4 0.072
nadh metabolic process GO:0006734 1 0.069
Rat
cellular divalent inorganic cation homeostasis GO:0072503 127 0.066
nucleoside triphosphate metabolic process GO:0009141 230 0.065
nucleoside metabolic process GO:0009116 246 0.065
cation homeostasis GO:0055080 212 0.065
sulfur compound metabolic process GO:0006790 100 0.064
purine nucleoside metabolic process GO:0042278 241 0.064
regulation of membrane potential GO:0042391 192 0.063
cristae formation GO:0042407 3 0.063
purine nucleoside monophosphate metabolic process GO:0009126 81 0.060
ribose phosphate metabolic process GO:0019693 291 0.058
nucleotide metabolic process GO:0009117 332 0.058
Rat
divalent inorganic cation homeostasis GO:0072507 138 0.058
mitochondrial membrane organization GO:0007006 26 0.058
cellular calcium ion homeostasis GO:0006874 119 0.056
response to oxidative stress GO:0006979 123 0.054
monocarboxylic acid metabolic process GO:0032787 191 0.052
anion transport GO:0006820 177 0.049
nucleoside monophosphate metabolic process GO:0009123 85 0.049
cellular amino acid metabolic process GO:0006520 103 0.047
carbohydrate derivative biosynthetic process GO:1901137 183 0.046
organophosphate biosynthetic process GO:0090407 122 0.044
cation transmembrane transport GO:0098655 266 0.043
organonitrogen compound biosynthetic process GO:1901566 192 0.042
translation GO:0006412 93 0.041
pyruvate metabolic process GO:0006090 28 0.041
small molecule biosynthetic process GO:0044283 132 0.040
membrane organization GO:0061024 245 0.040
calcium ion homeostasis GO:0055074 127 0.039
ribonucleoside metabolic process GO:0009119 245 0.038
ribonucleoside triphosphate metabolic process GO:0009199 220 0.037
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.037
glutamine family amino acid biosynthetic process GO:0009084 2 0.036
acyl coa metabolic process GO:0006637 19 0.036
synaptic transmission GO:0007268 329 0.035
action potential GO:0001508 78 0.034
heterocycle catabolic process GO:0046700 280 0.034
carbohydrate metabolic process GO:0005975 230 0.034
morphogenesis of embryonic epithelium GO:0016331 159 0.033
cellular ketone metabolic process GO:0042180 84 0.033
cofactor metabolic process GO:0051186 80 0.033
Rat
alpha amino acid metabolic process GO:1901605 59 0.033
dicarboxylic acid catabolic process GO:0043649 2 0.032
intrinsic apoptotic signaling pathway GO:0097193 132 0.032
glycerolipid metabolic process GO:0046486 122 0.031
organic cyclic compound catabolic process GO:1901361 295 0.030
purine nucleoside triphosphate metabolic process GO:0009144 226 0.030
endocytosis GO:0006897 168 0.029
nitrogen compound transport GO:0071705 271 0.029
ribonucleoside monophosphate biosynthetic process GO:0009156 9 0.029
organic anion transport GO:0015711 137 0.028
regulation of organelle organization GO:0033043 289 0.027
regulation of ion transport GO:0043269 215 0.027
inorganic cation transmembrane transport GO:0098662 207 0.027
carboxylic acid transport GO:0046942 100 0.027
positive regulation of cell death GO:0010942 224 0.027
muscle cell development GO:0055001 133 0.026
nucleoside phosphate biosynthetic process GO:1901293 79 0.026
cellular amine metabolic process GO:0044106 44 0.026
ribose phosphate biosynthetic process GO:0046390 59 0.025
organonitrogen compound catabolic process GO:1901565 264 0.025
regulation of transmembrane transport GO:0034762 128 0.025
inner mitochondrial membrane organization GO:0007007 5 0.025
positive regulation of programmed cell death GO:0043068 218 0.024
epithelial tube morphogenesis GO:0060562 303 0.024
purine ribonucleoside biosynthetic process GO:0046129 19 0.024
inorganic ion transmembrane transport GO:0098660 234 0.024
protein maturation GO:0051604 176 0.023
muscle cell differentiation GO:0042692 261 0.023
transmission of nerve impulse GO:0019226 76 0.023
cofactor biosynthetic process GO:0051188 41 0.022
cellular carbohydrate metabolic process GO:0044262 119 0.022
purine containing compound biosynthetic process GO:0072522 70 0.022
cell type specific apoptotic process GO:0097285 268 0.022
divalent metal ion transport GO:0070838 172 0.021
regulation of homeostatic process GO:0032844 182 0.021
muscle fiber development GO:0048747 76 0.021
regulation of ion transmembrane transport GO:0034765 119 0.021
organic hydroxy compound metabolic process GO:1901615 203 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.021
striated muscle tissue development GO:0014706 293 0.021
glutamate biosynthetic process GO:0006537 2 0.020
cellular lipid metabolic process GO:0044255 323 0.020
response to organic cyclic compound GO:0014070 198 0.020
acetyl coa metabolic process GO:0006084 8 0.020
thioester metabolic process GO:0035383 19 0.020
locomotory behavior GO:0007626 195 0.020
spermatogenesis GO:0007283 284 0.020
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.020
amine metabolic process GO:0009308 45 0.019
oxidoreduction coenzyme metabolic process GO:0006733 16 0.019
Rat
positive regulation of cellular amine metabolic process GO:0033240 5 0.019
protein localization to organelle GO:0033365 185 0.019
dephosphorylation GO:0016311 129 0.019
ribonucleotide biosynthetic process GO:0009260 59 0.019
multicellular organismal homeostasis GO:0048871 164 0.019
apoptotic signaling pathway GO:0097190 306 0.019
regulation of intracellular transport GO:0032386 159 0.019
intracellular protein transport GO:0006886 204 0.019
synapse organization GO:0050808 125 0.019
homeostasis of number of cells GO:0048872 210 0.019
regulation of lymphocyte activation GO:0051249 240 0.018
lipid homeostasis GO:0055088 63 0.018
cellular protein complex assembly GO:0043623 116 0.018
aromatic compound catabolic process GO:0019439 286 0.018
muscle tissue development GO:0060537 308 0.018
dna metabolic process GO:0006259 303 0.018
heme transport GO:0015886 2 0.018
regulation of t cell activation GO:0050863 170 0.018
regulation of protein transport GO:0051223 163 0.017
divalent inorganic cation transport GO:0072511 178 0.017
macromolecule catabolic process GO:0009057 281 0.017
positive regulation of apoptotic process GO:0043065 217 0.017
purine ribonucleotide biosynthetic process GO:0009152 59 0.017
regulation of protein localization GO:0032880 231 0.017
anatomical structure homeostasis GO:0060249 145 0.016
regulation of cellular amine metabolic process GO:0033238 20 0.016
lipid biosynthetic process GO:0008610 179 0.016
microtubule based process GO:0007017 236 0.016
cellular response to oxidative stress GO:0034599 76 0.016
regulation of cellular amino acid metabolic process GO:0006521 5 0.016
aerobic respiration GO:0009060 7 0.016
Rat
peptidyl amino acid modification GO:0018193 336 0.016
multicellular organismal signaling GO:0035637 91 0.016
multi multicellular organism process GO:0044706 109 0.016
regulation of cell activation GO:0050865 289 0.015
neuronal action potential GO:0019228 54 0.015
purine nucleotide biosynthetic process GO:0006164 65 0.015
alcohol metabolic process GO:0006066 116 0.015
oxidative phosphorylation GO:0006119 14 0.015
response to organonitrogen compound GO:0010243 246 0.015
sensory perception GO:0007600 245 0.015
positive regulation of protein kinase activity GO:0045860 144 0.015
long chain fatty acid import GO:0044539 2 0.015
innate immune response GO:0045087 157 0.015
organic hydroxy compound biosynthetic process GO:1901617 77 0.014
leukocyte differentiation GO:0002521 342 0.014
ossification GO:0001503 216 0.014
positive regulation of protein modification process GO:0031401 299 0.014
lymphocyte proliferation GO:0046651 164 0.014
blood vessel morphogenesis GO:0048514 285 0.014
regulation of secretion by cell GO:1903530 249 0.014
tissue homeostasis GO:0001894 115 0.014
mitochondrial fusion GO:0008053 9 0.014
ribonucleoside catabolic process GO:0042454 206 0.014
regulation of cytoplasmic transport GO:1903649 112 0.014
regulation of hydrolase activity GO:0051336 246 0.014
striated muscle cell development GO:0055002 125 0.014
immune effector process GO:0002252 321 0.014
aspartate family amino acid biosynthetic process GO:0009067 5 0.014
protein processing GO:0016485 163 0.014
phospholipid metabolic process GO:0006644 87 0.014
coagulation GO:0050817 78 0.014
nucleoside phosphate catabolic process GO:1901292 222 0.013
regulation of apoptotic signaling pathway GO:2001233 197 0.013
negative regulation of immune system process GO:0002683 209 0.013
regulation of peptidase activity GO:0052547 96 0.013
t cell activation GO:0042110 289 0.013
regulation of metal ion transport GO:0010959 106 0.013
negative regulation of organelle organization GO:0010639 90 0.013
response to reactive oxygen species GO:0000302 56 0.013
carbohydrate derivative catabolic process GO:1901136 231 0.013
response to inorganic substance GO:0010035 96 0.013
membrane fusion GO:0061025 38 0.013
organic acid transport GO:0015849 101 0.013
lymphocyte differentiation GO:0030098 242 0.013
regulation of cellular ketone metabolic process GO:0010565 66 0.013
organophosphate catabolic process GO:0046434 232 0.013
connective tissue development GO:0061448 179 0.013
placenta development GO:0001890 140 0.013
amide transport GO:0042886 138 0.013
nucleoside biosynthetic process GO:0009163 21 0.013
heart morphogenesis GO:0003007 178 0.013
extrinsic apoptotic signaling pathway GO:0097191 126 0.013
neuron apoptotic process GO:0051402 142 0.013
mitochondrial outer membrane permeabilization involved in programmed cell death GO:1902686 11 0.012
cytokine production GO:0001816 319 0.012
cellular amino acid catabolic process GO:0009063 25 0.012
regulation of establishment of protein localization GO:0070201 181 0.012
carbohydrate biosynthetic process GO:0016051 74 0.012
nucleoside triphosphate catabolic process GO:0009143 205 0.012
regulation of hormone levels GO:0010817 211 0.012
regulation of transporter activity GO:0032409 57 0.012
reactive oxygen species metabolic process GO:0072593 84 0.012
response to radiation GO:0009314 165 0.012
inflammatory response GO:0006954 244 0.012
male gamete generation GO:0048232 285 0.012
regulation of cytokine production GO:0001817 266 0.012
positive regulation of mitochondrion organization GO:0010822 17 0.012
embryonic epithelial tube formation GO:0001838 130 0.012
apoptotic mitochondrial changes GO:0008637 48 0.012
adult behavior GO:0030534 135 0.012
sodium ion transport GO:0006814 73 0.012
mitochondrial electron transport ubiquinol to cytochrome c GO:0006122 2 0.012
glucose homeostasis GO:0042593 128 0.012
purine nucleoside biosynthetic process GO:0042451 19 0.012
chromatin organization GO:0006325 206 0.012
posttranscriptional regulation of gene expression GO:0010608 155 0.012
regulation of intracellular protein transport GO:0033157 82 0.012
cell adhesion GO:0007155 329 0.011
pyridine containing compound catabolic process GO:0072526 4 0.011
peptide transport GO:0015833 133 0.011
positive regulation of organelle organization GO:0010638 128 0.011
development of primary sexual characteristics GO:0045137 143 0.011
myelination GO:0042552 74 0.011
small molecule catabolic process GO:0044282 71 0.011
regulation of reactive oxygen species metabolic process GO:2000377 40 0.011
nucleocytoplasmic transport GO:0006913 139 0.011
rhythmic process GO:0048511 174 0.011
negative regulation of cellular component organization GO:0051129 194 0.011
organ regeneration GO:0031100 2 0.011
glycosyl compound biosynthetic process GO:1901659 21 0.011
calcium ion transport GO:0006816 159 0.011
positive regulation of growth GO:0045927 104 0.011
cardiac muscle tissue development GO:0048738 130 0.011
skeletal system development GO:0001501 356 0.011
regulation of purine nucleotide metabolic process GO:1900542 169 0.011
nad metabolic process GO:0019674 7 0.011
Rat
response to molecule of bacterial origin GO:0002237 143 0.011
ensheathment of neurons GO:0007272 76 0.011
sequestering of calcium ion GO:0051208 18 0.011
regulation of secretion GO:0051046 274 0.011
detection of stimulus GO:0051606 84 0.011
nuclear transport GO:0051169 139 0.011
regulation of anion transport GO:0044070 27 0.011
cellular response to organonitrogen compound GO:0071417 145 0.011
neuron death GO:0070997 154 0.011
meiotic cell cycle GO:0051321 122 0.011
kidney development GO:0001822 213 0.011
nucleotide catabolic process GO:0009166 217 0.011
myeloid leukocyte differentiation GO:0002573 119 0.011
protein targeting GO:0006605 143 0.011
regulation of neuron death GO:1901214 134 0.010
leukocyte homeostasis GO:0001776 79 0.010
carboxylic acid biosynthetic process GO:0046394 86 0.010
mitochondrion transport along microtubule GO:0047497 3 0.010
negative regulation of cell proliferation GO:0008285 296 0.010
multicellular organism growth GO:0035264 161 0.010
wound healing GO:0042060 157 0.010
glycosyl compound catabolic process GO:1901658 206 0.010
positive regulation of hydrolase activity GO:0051345 148 0.010
regulation of atp biosynthetic process GO:2001169 3 0.010
detection of external stimulus GO:0009581 61 0.010
glutamate metabolic process GO:0006536 9 0.010
defecation GO:0030421 1 0.010
cytosolic calcium ion homeostasis GO:0051480 70 0.010
angiogenesis GO:0001525 201 0.010

Idh3a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.036
nervous system disease DOID:863 0 0.036
central nervous system disease DOID:331 0 0.029
neurodegenerative disease DOID:1289 0 0.028
immune system disease DOID:2914 0 0.026
hematopoietic system disease DOID:74 0 0.016
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
organ system cancer DOID:0050686 0 0.016
sensory system disease DOID:0050155 0 0.013
eye and adnexa disease DOID:1492 0 0.013
eye disease DOID:5614 0 0.013