Mus musculus

12 known processes

Ifi27l2a

interferon, alpha-inducible protein 27 like 2A

(Aliases: Isg12,Ifi27,2310061N23Rik,Isg12(b1))

Ifi27l2a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of viral genome replication GO:0045071 10 0.628
cellular response to interferon alpha GO:0035457 4 0.508
immune effector process GO:0002252 321 0.447
interspecies interaction between organisms GO:0044419 83 0.401
cellular nitrogen compound catabolic process GO:0044270 280 0.240
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.186
viral process GO:0016032 41 0.165
organic cyclic compound catabolic process GO:1901361 295 0.165
defense response to other organism GO:0098542 197 0.161
purine containing compound catabolic process GO:0072523 213 0.156
defense response to virus GO:0051607 68 0.143
heterocycle catabolic process GO:0046700 280 0.132
cellular macromolecule catabolic process GO:0044265 206 0.126
positive regulation of immunoglobulin production in mucosal tissue GO:2000558 1 0.119
aromatic compound catabolic process GO:0019439 286 0.105
negative regulation of viral process GO:0048525 23 0.103
purine containing compound metabolic process GO:0072521 311 0.100
cellular response to cytokine stimulus GO:0071345 189 0.097
toll like receptor 7 signaling pathway GO:0034154 4 0.093
positive regulation of type i interferon mediated signaling pathway GO:0060340 4 0.090
b cell chemotaxis GO:0035754 3 0.088
macromolecule catabolic process GO:0009057 281 0.088
lymphocyte mediated immunity GO:0002449 139 0.074
viral life cycle GO:0019058 36 0.074
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.072
antigen processing and presentation GO:0019882 47 0.071
negative regulation of multi organism process GO:0043901 68 0.065
metal ion homeostasis GO:0055065 189 0.061
negative regulation of cell proliferation GO:0008285 296 0.059
ribose phosphate metabolic process GO:0019693 291 0.058
purine ribonucleotide catabolic process GO:0009154 208 0.055
intracellular protein transport GO:0006886 204 0.055
cd8 positive alpha beta t cell proliferation GO:0035740 1 0.054
actin cytoskeleton organization GO:0030036 220 0.054
nucleoside triphosphate catabolic process GO:0009143 205 0.054
muscle tissue development GO:0060537 308 0.052
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.052
innate immune response GO:0045087 157 0.052
negative regulation of protein metabolic process GO:0051248 282 0.052
regulation of adaptive immune response GO:0002819 90 0.048
regulation of multi organism process GO:0043900 111 0.047
cellular response to dna damage stimulus GO:0006974 207 0.046
regulation of intracellular transport GO:0032386 159 0.046
nucleobase containing small molecule metabolic process GO:0055086 352 0.046
regulation of protein transport GO:0051223 163 0.045
defense response to bacterium GO:0042742 119 0.044
nucleotide biosynthetic process GO:0009165 78 0.043
t cell mediated immunity GO:0002456 50 0.042
nucleoside triphosphate metabolic process GO:0009141 230 0.042
nucleoside phosphate catabolic process GO:1901292 222 0.042
regulation of binding GO:0051098 111 0.042
organophosphate catabolic process GO:0046434 232 0.042
regulation of cellular ketone metabolic process GO:0010565 66 0.040
rna catabolic process GO:0006401 29 0.039
cellular homeostasis GO:0019725 240 0.039
striated muscle tissue development GO:0014706 293 0.039
nucleotide metabolic process GO:0009117 332 0.037
positive regulation of cellular component biogenesis GO:0044089 94 0.037
regulation of viral genome replication GO:0045069 13 0.037
regulation of t cell mediated immunity GO:0002709 34 0.037
response to organic cyclic compound GO:0014070 198 0.037
regulation of defense response GO:0031347 233 0.037
nucleoside phosphate metabolic process GO:0006753 338 0.036
purine nucleoside metabolic process GO:0042278 241 0.035
cellular metal ion homeostasis GO:0006875 151 0.035
glycosyl compound metabolic process GO:1901657 246 0.035
methylation GO:0032259 134 0.034
adaptive immune response GO:0002250 155 0.033
modification dependent protein catabolic process GO:0019941 133 0.033
positive regulation of rig i signaling pathway GO:1900246 1 0.032
regulation of intracellular protein transport GO:0033157 82 0.032
purine nucleotide catabolic process GO:0006195 211 0.031
ribonucleoside catabolic process GO:0042454 206 0.031
negative regulation of defense response to virus by host GO:0050689 1 0.031
protein methylation GO:0006479 81 0.031
protein modification by small protein conjugation GO:0032446 187 0.030
organonitrogen compound biosynthetic process GO:1901566 192 0.030
cellular protein catabolic process GO:0044257 155 0.029
cytokine production involved in immune response GO:0002367 34 0.029
regulation of t cell activation GO:0050863 170 0.029
small gtpase mediated signal transduction GO:0007264 97 0.028
carbohydrate homeostasis GO:0033500 128 0.028
purine ribonucleoside catabolic process GO:0046130 205 0.027
purine nucleotide metabolic process GO:0006163 302 0.027
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.027
positive regulation of cellular amine metabolic process GO:0033240 5 0.027
carbohydrate derivative catabolic process GO:1901136 231 0.027
histone modification GO:0016570 159 0.027
organophosphate biosynthetic process GO:0090407 122 0.026
dna damage response signal transduction resulting in transcription GO:0042772 2 0.026
purine ribonucleotide metabolic process GO:0009150 290 0.026
negative regulation of hydrolase activity GO:0051346 71 0.026
protein processing GO:0016485 163 0.026
fat cell differentiation GO:0045444 160 0.026
regulation of type i interferon mediated signaling pathway GO:0060338 7 0.025
regulation of protein localization GO:0032880 231 0.025
cellular chemical homeostasis GO:0055082 215 0.025
protein acylation GO:0043543 64 0.025
purine nucleotide biosynthetic process GO:0006164 65 0.025
cytoplasmic transport GO:0016482 234 0.024
purine ribonucleoside metabolic process GO:0046128 241 0.024
regulation of homeostatic process GO:0032844 182 0.024
nucleotide catabolic process GO:0009166 217 0.024
cellular amine metabolic process GO:0044106 44 0.024
regulation of toll like receptor 9 signaling pathway GO:0034163 3 0.023
negative regulation of cellular protein metabolic process GO:0032269 247 0.023
cellular amino acid metabolic process GO:0006520 103 0.023
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.023
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.023
regulation of t helper 2 cell cytokine production GO:2000551 3 0.023
cation homeostasis GO:0055080 212 0.023
positive regulation of secretion GO:0051047 130 0.023
response to interferon alpha GO:0035455 7 0.022
keratinocyte differentiation GO:0030216 48 0.022
regulation of viral transcription GO:0046782 3 0.022
endocytosis GO:0006897 168 0.022
rig i signaling pathway GO:0039529 4 0.022
carbohydrate metabolic process GO:0005975 230 0.021
negative regulation of peptidase activity GO:0010466 46 0.021
ear development GO:0043583 200 0.021
purine nucleoside catabolic process GO:0006152 205 0.021
protein modification by small protein conjugation or removal GO:0070647 207 0.021
rna phosphodiester bond hydrolysis GO:0090501 19 0.020
maintenance of location GO:0051235 89 0.020
lymphocyte differentiation GO:0030098 242 0.020
skeletal muscle organ development GO:0060538 163 0.020
central nervous system neuron differentiation GO:0021953 162 0.020
multicellular organism growth GO:0035264 161 0.020
purine nucleoside triphosphate catabolic process GO:0009146 203 0.020
glucose homeostasis GO:0042593 128 0.020
negative regulation of protein transport GO:0051224 46 0.020
purine nucleoside triphosphate metabolic process GO:0009144 226 0.020
chromatin organization GO:0006325 206 0.019
regulation of cellular catabolic process GO:0031329 242 0.019
dna metabolic process GO:0006259 303 0.019
glycosyl compound catabolic process GO:1901658 206 0.019
t cell activation GO:0042110 289 0.019
epithelial tube morphogenesis GO:0060562 303 0.019
ribonucleotide metabolic process GO:0009259 291 0.019
autophagy GO:0006914 45 0.019
positive regulation of kinase activity GO:0033674 155 0.018
regulation of cytoplasmic transport GO:1903649 112 0.018
regulation of cellular component biogenesis GO:0044087 181 0.018
nucleoside phosphate biosynthetic process GO:1901293 79 0.018
regulation of cd8 positive alpha beta t cell proliferation GO:2000564 1 0.018
positive regulation of natural killer cell chemotaxis GO:2000503 1 0.018
cation transport GO:0006812 399 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.018
leukocyte activation involved in immune response GO:0002366 126 0.018
positive regulation of interferon alpha production GO:0032727 4 0.018
regulation of establishment of protein localization GO:0070201 181 0.017
macromolecule methylation GO:0043414 120 0.017
antigen processing and presentation of exogenous peptide antigen GO:0002478 21 0.017
regulation of organelle organization GO:0033043 289 0.017
regulation of t helper 1 cell cytokine production GO:2000554 1 0.017
male gamete generation GO:0048232 285 0.017
phagocytosis GO:0006909 66 0.016
antigen processing and presentation of peptide antigen GO:0048002 29 0.016
multi multicellular organism process GO:0044706 109 0.016
digestion GO:0007586 40 0.016
glycoprotein metabolic process GO:0009100 116 0.016
cellular lipid metabolic process GO:0044255 323 0.016
type i interferon signaling pathway GO:0060337 10 0.016
myeloid leukocyte differentiation GO:0002573 119 0.016
ribonucleoside metabolic process GO:0009119 245 0.016
regulation of defense response to virus by host GO:0050691 8 0.016
positive regulation of adaptive immune response GO:0002821 61 0.016
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 35 0.015
guanosine containing compound metabolic process GO:1901068 144 0.015
oxidation reduction process GO:0055114 342 0.015
epithelial cell proliferation GO:0050673 174 0.015
skin development GO:0043588 220 0.015
protein maturation GO:0051604 176 0.015
positive regulation of eosinophil migration GO:2000418 2 0.015
protein secretion GO:0009306 111 0.015
cellular response to interferon beta GO:0035458 21 0.015
negative regulation of lymphocyte activation GO:0051250 91 0.015
calcium ion homeostasis GO:0055074 127 0.015
regulation of myd88 independent toll like receptor signaling pathway GO:0034127 1 0.015
regulation of alpha beta t cell proliferation GO:0046640 18 0.015
organelle assembly GO:0070925 177 0.015
divalent metal ion transport GO:0070838 172 0.015
transition metal ion transport GO:0000041 38 0.015
response to phenylpropanoid GO:0080184 22 0.015
ras protein signal transduction GO:0007265 77 0.015
regulation of nucleotide metabolic process GO:0006140 169 0.015
response to type i interferon GO:0034340 12 0.015
positive regulation of nervous system development GO:0051962 221 0.014
regulation of dna binding GO:0051101 39 0.014
negative regulation of interferon beta production GO:0032688 3 0.014
nucleocytoplasmic transport GO:0006913 139 0.014
monocarboxylic acid metabolic process GO:0032787 191 0.014
positive regulation of response to cytokine stimulus GO:0060760 11 0.014
regulation of defense response to virus GO:0050688 18 0.014
developmental maturation GO:0021700 193 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.014
sequestering of metal ion GO:0051238 19 0.014
regulation of lymphocyte activation GO:0051249 240 0.014
keratinocyte proliferation GO:0043616 21 0.014
ribonucleoside triphosphate catabolic process GO:0009203 199 0.013
peptidyl lysine methylation GO:0018022 29 0.013
intracellular transport of virus GO:0075733 1 0.013
t helper 2 cell cytokine production GO:0035745 4 0.013
engulfment of apoptotic cell GO:0043652 3 0.013
regulation of myd88 dependent toll like receptor signaling pathway GO:0034124 2 0.013
cellular ketone metabolic process GO:0042180 84 0.013
viral genome replication GO:0019079 17 0.013
isg15 protein conjugation GO:0032020 4 0.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.013
calcium ion transport GO:0006816 159 0.013
glycerolipid metabolic process GO:0046486 122 0.013
regulation of cellular amino acid metabolic process GO:0006521 5 0.013
spermatogenesis GO:0007283 284 0.013
protein oligomerization GO:0051259 67 0.012
positive regulation of immune effector process GO:0002699 107 0.012
alpha beta t cell activation GO:0046631 91 0.012
positive regulation of secretion by cell GO:1903532 114 0.012
mitotic cell cycle GO:0000278 195 0.012
cellular response to interferon gamma GO:0071346 25 0.012
regulation of eosinophil migration GO:2000416 2 0.012
regulation of purine nucleotide metabolic process GO:1900542 169 0.012
neuromuscular process GO:0050905 99 0.012
leukocyte mediated immunity GO:0002443 174 0.012
regulation of leukocyte mediated immunity GO:0002703 104 0.012
regulation of protein kinase activity GO:0045859 232 0.012
negative regulation of protein maturation GO:1903318 79 0.012
response to interferon gamma GO:0034341 34 0.012
cytokine production GO:0001816 319 0.012
regulation of hormone levels GO:0010817 211 0.012
negative regulation of protein modification process GO:0031400 163 0.012
positive regulation of thymocyte migration GO:2000412 2 0.012
negative regulation of cellular amine metabolic process GO:0033239 1 0.012
fatty acid metabolic process GO:0006631 121 0.012
viral gene expression GO:0019080 3 0.012
alpha beta t cell differentiation GO:0046632 69 0.012
cellular response to type i interferon GO:0071357 10 0.012
divalent inorganic cation transport GO:0072511 178 0.011
protein activation cascade GO:0072376 19 0.011
regulation of system process GO:0044057 200 0.011
regulation of hydrolase activity GO:0051336 246 0.011
lymphocyte proliferation GO:0046651 164 0.011
cd4 positive alpha beta t cell activation GO:0035710 45 0.011
negative regulation of binding GO:0051100 39 0.011
negative regulation of proteolysis GO:0045861 74 0.011
negative regulation of molecular function GO:0044092 258 0.011
regulation of cell adhesion GO:0030155 154 0.011
regulation of cytokine production GO:0001817 266 0.011
regulation of actin filament based process GO:0032970 99 0.011
viral transcription GO:0019083 3 0.011
lipid modification GO:0030258 65 0.011
protein alkylation GO:0008213 81 0.011
cellular component assembly involved in morphogenesis GO:0010927 139 0.011
female sex differentiation GO:0046660 84 0.011
regulation of neuron death GO:1901214 134 0.011
positive regulation of ossification GO:0045778 47 0.011
response to dsrna GO:0043331 30 0.011
cellular response to organonitrogen compound GO:0071417 145 0.011
guanosine containing compound catabolic process GO:1901069 144 0.011
cell adhesion GO:0007155 329 0.010
regulation of cell cycle GO:0051726 281 0.010
protein polymerization GO:0051258 57 0.010
interleukin 1 production GO:0032612 31 0.010
positive regulation of organelle organization GO:0010638 128 0.010
posttranscriptional regulation of gene expression GO:0010608 155 0.010
epithelial cell development GO:0002064 159 0.010
muscle cell differentiation GO:0042692 261 0.010
positive regulation of protein modification process GO:0031401 299 0.010
regulation of dendritic cell dendrite assembly GO:2000547 2 0.010
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.010
positive regulation of binding GO:0051099 49 0.010
neuron apoptotic process GO:0051402 142 0.010
membrane organization GO:0061024 245 0.010
regulation of production of molecular mediator of immune response GO:0002700 65 0.010
immunoglobulin mediated immune response GO:0016064 69 0.010
signal transduction by p53 class mediator GO:0072331 51 0.010
internal peptidyl lysine acetylation GO:0018393 42 0.010

Ifi27l2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.010
acquired metabolic disease DOID:0060158 0 0.010