Mus musculus

30 known processes

Ifna1

interferon alpha 1

(Aliases: Ifa1)

Ifna1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular ketone metabolic process GO:0042180 84 0.441
regulation of cellular amine metabolic process GO:0033238 20 0.370
defense response to other organism GO:0098542 197 0.270
regulation of cellular ketone metabolic process GO:0010565 66 0.269
defense response to bacterium GO:0042742 119 0.268
amine metabolic process GO:0009308 45 0.258
negative regulation of lymphocyte activation GO:0051250 91 0.162
Human
purine containing compound metabolic process GO:0072521 311 0.152
reactive oxygen species metabolic process GO:0072593 84 0.130
regulation of secretion GO:0051046 274 0.129
Human
reactive nitrogen species metabolic process GO:2001057 0 0.128
regulation of reactive oxygen species metabolic process GO:2000377 40 0.122
regulation of cell activation GO:0050865 289 0.119
Human
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.110
natural killer cell activation involved in immune response GO:0002323 10 0.106
regulation of cellular amino acid metabolic process GO:0006521 5 0.103
defense response to gram positive bacterium GO:0050830 50 0.103
oxidation reduction process GO:0055114 342 0.101
positive regulation of protein phosphorylation GO:0001934 242 0.099
Human
regulation of leukocyte mediated immunity GO:0002703 104 0.099
Human
cellular amine metabolic process GO:0044106 44 0.088
adaptive immune response GO:0002250 155 0.085
Human
immune effector process GO:0002252 321 0.085
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.085
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.083
cellular response to biotic stimulus GO:0071216 92 0.083
reactive oxygen species biosynthetic process GO:1903409 8 0.081
response to molecule of bacterial origin GO:0002237 143 0.077
response to organonitrogen compound GO:0010243 246 0.076
anion transport GO:0006820 177 0.075
response to lipopolysaccharide GO:0032496 128 0.071
nucleotide metabolic process GO:0009117 332 0.071
cytokine production GO:0001816 319 0.069
Human
interleukin 13 secretion GO:0072611 2 0.069
Human
regulation of lymphocyte mediated immunity GO:0002706 84 0.069
Human
cation homeostasis GO:0055080 212 0.068
positive regulation of cellular amine metabolic process GO:0033240 5 0.068
regulation of interleukin 5 secretion GO:2000662 2 0.066
Human
negative regulation of secretion GO:0051048 61 0.066
Human
regulation of protein secretion GO:0050708 82 0.061
Human
regulation of anion transport GO:0044070 27 0.061
regulation of cell cycle GO:0051726 281 0.061
Mouse
interleukin 5 secretion GO:0072603 2 0.060
Human
negative regulation of cell proliferation GO:0008285 296 0.060
cellular amino acid metabolic process GO:0006520 103 0.059
peptidyl tyrosine phosphorylation GO:0018108 143 0.059
Human
response to nutrient levels GO:0031667 109 0.058
regulation of purine nucleotide metabolic process GO:1900542 169 0.058
negative regulation of phosphate metabolic process GO:0045936 184 0.058
negative regulation of intracellular signal transduction GO:1902532 167 0.058
divalent inorganic cation homeostasis GO:0072507 138 0.057
negative regulation of phosphorylation GO:0042326 166 0.055
lymphocyte activation involved in immune response GO:0002285 93 0.054
regulation of cytokine secretion GO:0050707 61 0.054
Human
organic acid biosynthetic process GO:0016053 86 0.054
t helper 2 cell cytokine production GO:0035745 4 0.053
Human
negative regulation of mapk cascade GO:0043409 65 0.053
lymphocyte mediated immunity GO:0002449 139 0.051
Human
cellular calcium ion homeostasis GO:0006874 119 0.050
leukocyte activation involved in immune response GO:0002366 126 0.050
ossification GO:0001503 216 0.050
regulation of lymphocyte activation GO:0051249 240 0.050
Human
cellular chemical homeostasis GO:0055082 215 0.050
regulation of hormone levels GO:0010817 211 0.050
b cell activation GO:0042113 161 0.049
Mouse
carbohydrate derivative biosynthetic process GO:1901137 183 0.049
carboxylic acid biosynthetic process GO:0046394 86 0.048
cellular lipid metabolic process GO:0044255 323 0.046
negative regulation of phosphorus metabolic process GO:0010563 184 0.046
positive regulation of cytokine production GO:0001819 174 0.045
regulation of organelle organization GO:0033043 289 0.045
apoptotic signaling pathway GO:0097190 306 0.045
Mouse
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.044
positive regulation of defense response GO:0031349 124 0.043
regulation of interleukin 13 secretion GO:2000665 2 0.043
Human
positive regulation of cellular ph reduction GO:0032849 2 0.042
regulation of secretion by cell GO:1903530 249 0.042
Human
g protein coupled receptor signaling pathway GO:0007186 243 0.041
response to inorganic substance GO:0010035 96 0.041
regulation of nucleotide metabolic process GO:0006140 169 0.040
negative regulation of protein transport GO:0051224 46 0.040
Human
regulation of hydrolase activity GO:0051336 246 0.038
t cell differentiation GO:0030217 174 0.038
Human
regulation of protein localization GO:0032880 231 0.037
Human
negative regulation of cytokine production GO:0001818 84 0.037
Human
metal ion homeostasis GO:0055065 189 0.037
cellular response to lipid GO:0071396 145 0.037
gtp catabolic process GO:0006184 143 0.037
organic cyclic compound catabolic process GO:1901361 295 0.036
nitric oxide metabolic process GO:0046209 25 0.036
lymphocyte proliferation GO:0046651 164 0.036
regulation of leukocyte differentiation GO:1902105 159 0.035
Human
positive regulation of programmed cell death GO:0043068 218 0.034
nucleobase containing small molecule metabolic process GO:0055086 352 0.034
regulation of map kinase activity GO:0043405 120 0.033
cytokine secretion GO:0050663 72 0.033
Human
ribonucleotide metabolic process GO:0009259 291 0.033
response to extracellular stimulus GO:0009991 127 0.032
aromatic compound catabolic process GO:0019439 286 0.032
monocarboxylic acid metabolic process GO:0032787 191 0.032
rhythmic process GO:0048511 174 0.031
i kappab kinase nf kappab signaling GO:0007249 85 0.031
monocarboxylic acid biosynthetic process GO:0072330 61 0.031
cell killing GO:0001906 67 0.031
actin cytoskeleton organization GO:0030036 220 0.031
ribose phosphate metabolic process GO:0019693 291 0.031
organonitrogen compound catabolic process GO:1901565 264 0.030
regulation of defense response GO:0031347 233 0.030
glycosyl compound metabolic process GO:1901657 246 0.030
leukocyte mediated immunity GO:0002443 174 0.030
Human
cell activation involved in immune response GO:0002263 126 0.030
negative regulation of secretion by cell GO:1903531 54 0.030
Human
regulation of cellular component biogenesis GO:0044087 181 0.030
peptidyl amino acid modification GO:0018193 336 0.029
Human
regulation of cell cycle process GO:0010564 160 0.029
regulation of feeding behavior GO:0060259 3 0.029
regulation of multi organism process GO:0043900 111 0.029
Human
prostate gland epithelium morphogenesis GO:0060740 31 0.029
cellular divalent inorganic cation homeostasis GO:0072503 127 0.028
muscle cell development GO:0055001 133 0.028
regulation of cytokine production GO:0001817 266 0.028
Human
energy derivation by oxidation of organic compounds GO:0015980 77 0.028
regulation of apoptotic signaling pathway GO:2001233 197 0.028
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.028
ribonucleotide biosynthetic process GO:0009260 59 0.028
purine ribonucleotide metabolic process GO:0009150 290 0.027
renal system process GO:0003014 48 0.027
interspecies interaction between organisms GO:0044419 83 0.027
Human
organic anion transport GO:0015711 137 0.027
negative regulation of immune system process GO:0002683 209 0.027
Human
lipid biosynthetic process GO:0008610 179 0.027
positive regulation of camp mediated signaling GO:0043950 3 0.026
regulation of jnk cascade GO:0046328 62 0.026
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.026
Human
response to molecule of fungal origin GO:0002238 4 0.026
cellular response to lipopolysaccharide GO:0071222 77 0.026
purine ribonucleotide catabolic process GO:0009154 208 0.026
synaptic transmission GO:0007268 329 0.025
natural killer cell activation GO:0030101 44 0.025
nitric oxide biosynthetic process GO:0006809 25 0.025
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.025
morphogenesis of a branching structure GO:0001763 203 0.025
negative regulation of molecular function GO:0044092 258 0.025
organic hydroxy compound biosynthetic process GO:1901617 77 0.025
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.024
Human
regulation of t helper 2 cell cytokine production GO:2000551 3 0.024
Human
organophosphate catabolic process GO:0046434 232 0.024
heterocycle catabolic process GO:0046700 280 0.024
organonitrogen compound biosynthetic process GO:1901566 192 0.024
g protein coupled acetylcholine receptor signaling pathway GO:0007213 4 0.024
leukocyte proliferation GO:0070661 172 0.024
response to organic cyclic compound GO:0014070 198 0.024
positive regulation of secretion by cell GO:1903532 114 0.023
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.023
Human
leukocyte mediated cytotoxicity GO:0001909 62 0.023
protein localization to organelle GO:0033365 185 0.023
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.023
Human
calcium ion homeostasis GO:0055074 127 0.023
purine nucleotide biosynthetic process GO:0006164 65 0.023
purine nucleotide metabolic process GO:0006163 302 0.023
regulation of lymphocyte differentiation GO:0045619 107 0.022
Human
cytokine mediated signaling pathway GO:0019221 115 0.022
Mouse
positive regulation of protein modification process GO:0031401 299 0.022
Human
carboxylic acid transport GO:0046942 100 0.022
regulation of renal sodium excretion GO:0035813 3 0.022
negative regulation of leukocyte differentiation GO:1902106 51 0.022
Human
regulation of membrane potential GO:0042391 192 0.022
purine nucleoside triphosphate metabolic process GO:0009144 226 0.022
mapk cascade GO:0000165 281 0.022
regulation of establishment of protein localization GO:0070201 181 0.022
Human
peptidyl tyrosine modification GO:0018212 145 0.022
Human
response to oxidative stress GO:0006979 123 0.022
myeloid cell differentiation GO:0030099 233 0.022
protein maturation GO:0051604 176 0.021
negative regulation of interleukin 13 secretion GO:2000666 1 0.021
Human
regulation of t cell activation GO:0050863 170 0.021
Human
positive regulation of secretion GO:0051047 130 0.021
organelle assembly GO:0070925 177 0.021
purine nucleotide catabolic process GO:0006195 211 0.021
negative regulation of multi organism process GO:0043901 68 0.021
Human
negative regulation of lymphocyte mediated immunity GO:0002707 21 0.021
Human
nucleoside catabolic process GO:0009164 206 0.020
regulation of protein kinase activity GO:0045859 232 0.020
regulation of postsynaptic membrane potential GO:0060078 48 0.020
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.020
lipid catabolic process GO:0016042 69 0.020
rho protein signal transduction GO:0007266 32 0.020
extrinsic apoptotic signaling pathway GO:0097191 126 0.020
regulation of cellular response to stress GO:0080135 159 0.020
regulation of endocytosis GO:0030100 69 0.020
alpha amino acid metabolic process GO:1901605 59 0.019
cellular component assembly involved in morphogenesis GO:0010927 139 0.019
regulation of cell killing GO:0031341 40 0.019
negative regulation of adaptive immune response GO:0002820 25 0.019
Human
leukocyte differentiation GO:0002521 342 0.019
Human Mouse
cellular metal ion homeostasis GO:0006875 151 0.019
regulation of homeostatic process GO:0032844 182 0.019
sequestering of calcium ion GO:0051208 18 0.019
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.019
cellular response to cadmium ion GO:0071276 3 0.019
blood circulation GO:0008015 195 0.019
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.019
prostate gland development GO:0030850 48 0.019
positive regulation of response to wounding GO:1903036 66 0.019
purine containing compound catabolic process GO:0072523 213 0.019
negative regulation of erk1 and erk2 cascade GO:0070373 21 0.018
positive regulation of nucleotide metabolic process GO:0045981 114 0.018
production of molecular mediator of immune response GO:0002440 103 0.018
Human
regulation of leukocyte proliferation GO:0070663 121 0.018
nucleoside triphosphate metabolic process GO:0009141 230 0.018
positive regulation of nervous system development GO:0051962 221 0.018
transmembrane transport GO:0055085 412 0.018
defense response to virus GO:0051607 68 0.018
nucleoside metabolic process GO:0009116 246 0.018
multicellular organismal homeostasis GO:0048871 164 0.017
organic acid transport GO:0015849 101 0.017
negative regulation of lymphocyte proliferation GO:0050672 45 0.017
anatomical structure maturation GO:0071695 49 0.017
cerebral cortex tangential migration using cell axon interactions GO:0021824 3 0.017
cellular response to organonitrogen compound GO:0071417 145 0.017
regulation of leukocyte mediated cytotoxicity GO:0001910 38 0.017
nucleocytoplasmic transport GO:0006913 139 0.017
regulation of anatomical structure size GO:0090066 178 0.017
regulation of cell growth GO:0001558 91 0.017
urogenital system development GO:0001655 261 0.017
negative regulation of t cell mediated immunity GO:0002710 9 0.016
Human
positive regulation of gtp catabolic process GO:0033126 85 0.016
spermatogenesis GO:0007283 284 0.016
purine nucleoside metabolic process GO:0042278 241 0.016
negative regulation of t cell activation GO:0050868 65 0.016
Human
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.016
Human
regulation of jak stat cascade GO:0046425 34 0.016
Human
negative regulation of protein metabolic process GO:0051248 282 0.016
protein import GO:0017038 101 0.016
regulation of adaptive immune response GO:0002819 90 0.016
Human
regulation of androgen receptor signaling pathway GO:0060765 3 0.015
t cell mediated immunity GO:0002456 50 0.015
Human
sphingolipid metabolic process GO:0006665 45 0.015
ribonucleoside metabolic process GO:0009119 245 0.015
cellular amino acid catabolic process GO:0009063 25 0.015
negative regulation of interleukin 13 production GO:0032696 2 0.015
Human
t cell activation GO:0042110 289 0.015
small molecule catabolic process GO:0044282 71 0.015
heart trabecula morphogenesis GO:0061384 26 0.015
cellular ion homeostasis GO:0006873 165 0.015
purine nucleoside triphosphate catabolic process GO:0009146 203 0.015
negative regulation of interleukin 5 production GO:0032714 4 0.015
Human
negative regulation of cell cycle GO:0045786 123 0.015
positive regulation of cell death GO:0010942 224 0.015
glucan metabolic process GO:0044042 32 0.015
positive regulation of apoptotic process GO:0043065 217 0.015
cellular response to cytokine stimulus GO:0071345 189 0.015
Mouse
regulation of protein transport GO:0051223 163 0.015
Human
small molecule biosynthetic process GO:0044283 132 0.015
positive regulation of organelle organization GO:0010638 128 0.015
regulation of nitric oxide biosynthetic process GO:0045428 18 0.015
positive regulation of protein kinase activity GO:0045860 144 0.015
response to peptide GO:1901652 136 0.015
negative regulation of interleukin 5 secretion GO:2000663 1 0.015
Human
response to reactive oxygen species GO:0000302 56 0.015
regulation of cell cycle phase transition GO:1901987 77 0.014
positive regulation of cell activation GO:0050867 158 0.014
cellular protein complex assembly GO:0043623 116 0.014
regulation of stress activated mapk cascade GO:0032872 69 0.014
regulation of cellular catabolic process GO:0031329 242 0.014
innate immune response activating cell surface receptor signaling pathway GO:0002220 4 0.014
endocytosis GO:0006897 168 0.014
nucleoside phosphate catabolic process GO:1901292 222 0.014
negative regulation of protein phosphorylation GO:0001933 126 0.014
t cell proliferation GO:0042098 120 0.014
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.014
regulation of interferon gamma production GO:0032649 57 0.014
entry into host GO:0044409 15 0.014
Human
cell growth GO:0016049 130 0.014
regulation of transferase activity GO:0051338 263 0.014
regulation of body fluid levels GO:0050878 162 0.014
forebrain development GO:0030900 302 0.014
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.014
cell adhesion GO:0007155 329 0.014
stress activated protein kinase signaling cascade GO:0031098 81 0.014
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.013
Human
jak stat cascade GO:0007259 42 0.013
Human
carbohydrate derivative catabolic process GO:1901136 231 0.013
multi multicellular organism process GO:0044706 109 0.013
protein oligomerization GO:0051259 67 0.013
negative regulation of cell activation GO:0050866 111 0.013
Human
regulation of protein serine threonine kinase activity GO:0071900 157 0.013
maternal placenta development GO:0001893 20 0.013
cyclic purine nucleotide metabolic process GO:0052652 43 0.013
purine ribonucleoside metabolic process GO:0046128 241 0.013
steroid biosynthetic process GO:0006694 47 0.013
positive regulation of growth GO:0045927 104 0.013
hormone metabolic process GO:0042445 86 0.013
cell type specific apoptotic process GO:0097285 268 0.013
extracellular structure organization GO:0043062 148 0.013
membrane lipid metabolic process GO:0006643 53 0.013
regulation of circadian sleep wake cycle GO:0042749 3 0.013
lung development GO:0030324 164 0.013
camp metabolic process GO:0046058 40 0.013
purine ribonucleoside catabolic process GO:0046130 205 0.013
nucleoside phosphate metabolic process GO:0006753 338 0.013
purine nucleoside catabolic process GO:0006152 205 0.012
myosin filament assembly GO:0031034 2 0.012
regulation of neurotransmitter levels GO:0001505 87 0.012
regulation of excitatory postsynaptic membrane potential GO:0060079 41 0.012
ion transmembrane transport GO:0034220 361 0.012
organelle fission GO:0048285 170 0.012
organ growth GO:0035265 117 0.012
ribose phosphate biosynthetic process GO:0046390 59 0.012
regulation of cytoskeleton organization GO:0051493 122 0.012
generation of precursor metabolites and energy GO:0006091 103 0.012
regulation of mitotic cell cycle phase transition GO:1901990 73 0.012
regulation of systemic arterial blood pressure GO:0003073 61 0.012
cellular response to external stimulus GO:0071496 88 0.012
regulation of mitotic cell cycle GO:0007346 126 0.012
protein import into nucleus GO:0006606 95 0.012
regulation of cytokine production involved in immune response GO:0002718 26 0.012
Human
cation transmembrane transport GO:0098655 266 0.012
myotube differentiation GO:0014902 105 0.012
negative regulation of viral entry into host cell GO:0046597 10 0.012
Human
positive regulation of renal sodium excretion GO:0035815 2 0.012
cellular response to acid chemical GO:0071229 68 0.012
ribonucleoside catabolic process GO:0042454 206 0.012
cellular response to hormone stimulus GO:0032870 150 0.012
positive regulation of amino acid transport GO:0051957 4 0.012
regulation of ras protein signal transduction GO:0046578 114 0.012
myeloid leukocyte differentiation GO:0002573 119 0.012
negative regulation of protein secretion GO:0050709 20 0.012
Human
organic hydroxy compound catabolic process GO:1901616 25 0.012
nuclear division GO:0000280 158 0.011
t cell activation involved in immune response GO:0002286 43 0.011
response to steroid hormone GO:0048545 56 0.011
negative regulation of growth GO:0045926 99 0.011
chemokine production GO:0032602 34 0.011
negative regulation of camp mediated signaling GO:0043951 3 0.011
hormone secretion GO:0046879 128 0.011
cellular response to prostaglandin stimulus GO:0071379 2 0.011
placenta development GO:0001890 140 0.011
positive regulation of hydrolase activity GO:0051345 148 0.011
glycogen metabolic process GO:0005977 32 0.011
regulation of t cell differentiation GO:0045580 83 0.011
Human
response to mineralocorticoid GO:0051385 1 0.011
synaptic vesicle localization GO:0097479 59 0.011
nucleotide catabolic process GO:0009166 217 0.011
regulation of cellular ph reduction GO:0032847 2 0.011
ribonucleoside triphosphate metabolic process GO:0009199 220 0.011
b cell differentiation GO:0030183 78 0.011
Mouse
organic hydroxy compound metabolic process GO:1901615 203 0.011
cellular response to inorganic substance GO:0071241 37 0.011
sensory perception of chemical stimulus GO:0007606 51 0.011
cytokine production involved in immune response GO:0002367 34 0.011
Human
autophagy GO:0006914 45 0.011
regulation of glutamate secretion GO:0014048 3 0.011
cellular homeostasis GO:0019725 240 0.011
positive regulation of wnt signaling pathway GO:0030177 45 0.011
respiratory tube development GO:0030323 167 0.011
positive regulation of lymphocyte activation GO:0051251 140 0.011
regulation of erk1 and erk2 cascade GO:0070372 71 0.011
cellular nitrogen compound catabolic process GO:0044270 280 0.011
protein targeting GO:0006605 143 0.011
multicellular organismal signaling GO:0035637 91 0.011
response to drug GO:0042493 75 0.011
regulation of kinase activity GO:0043549 249 0.011
protein secretion GO:0009306 111 0.011
Human
bone mineralization GO:0030282 54 0.011
regulation of autophagy GO:0010506 30 0.011
regulation of production of molecular mediator of immune response GO:0002700 65 0.011
Human
male gamete generation GO:0048232 285 0.010
regulation of mapk cascade GO:0043408 248 0.010
cytoplasmic transport GO:0016482 234 0.010
renal sodium excretion GO:0035812 3 0.010
mitotic cell cycle process GO:1903047 159 0.010
biomineral tissue development GO:0031214 64 0.010
membrane invagination GO:0010324 17 0.010
negative regulation of synapse assembly GO:0051964 3 0.010
fertilization GO:0009566 127 0.010
negative regulation of cellular component organization GO:0051129 194 0.010
positive regulation of inflammatory response GO:0050729 47 0.010
regulation of response to wounding GO:1903034 189 0.010
amide transport GO:0042886 138 0.010
engulfment of apoptotic cell GO:0043652 3 0.010
regulation of actin filament polymerization GO:0030833 38 0.010
ribonucleoside triphosphate catabolic process GO:0009203 199 0.010
striated muscle cell development GO:0055002 125 0.010
development of primary sexual characteristics GO:0045137 143 0.010
maternal process involved in female pregnancy GO:0060135 32 0.010
ras protein signal transduction GO:0007265 77 0.010
response to metal ion GO:0010038 47 0.010

Ifna1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 0 0.024
disease of anatomical entity DOID:7 0 0.024
nervous system disease DOID:863 0 0.024
disease of metabolism DOID:0014667 0 0.013