|
|
positive regulation of isotype switching to igg isotypes
|
GO:0048304 |
7 |
1.000
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
1.000
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
1.000
|
|
|
|
regulation of inflammatory response to antigenic stimulus
|
GO:0002861 |
21 |
1.000
|
|
|
|
regulation of chronic inflammatory response to antigenic stimulus
|
GO:0002874 |
3 |
1.000
|
|
|
|
somatic diversification of immunoglobulins involved in immune response
|
GO:0002208 |
36 |
1.000
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
1.000
|
|
|
|
negative regulation of inflammatory response to antigenic stimulus
|
GO:0002862 |
10 |
0.999
|
|
|
|
somatic recombination of immunoglobulin genes involved in immune response
|
GO:0002204 |
36 |
0.999
|
|
|
|
dna recombination
|
GO:0006310 |
92 |
0.999
|
|
|
|
isotype switching to igg isotypes
|
GO:0048291 |
10 |
0.999
|
|
|
|
regulation of growth of symbiont in host
|
GO:0044126 |
19 |
0.998
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.998
|
|
|
|
positive regulation of chronic inflammatory response
|
GO:0002678 |
4 |
0.997
|
|
|
|
positive regulation of b cell mediated immunity
|
GO:0002714 |
26 |
0.997
|
|
|
|
somatic diversification of immune receptors
|
GO:0002200 |
53 |
0.996
|
|
|
|
immunoglobulin production involved in immunoglobulin mediated immune response
|
GO:0002381 |
43 |
0.996
|
|
|
|
immunoglobulin secretion
|
GO:0048305 |
17 |
0.996
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.996
|
|
|
|
necroptotic signaling pathway
|
GO:0097527 |
3 |
0.995
|
|
|
|
somatic recombination of immunoglobulin gene segments
|
GO:0016447 |
42 |
0.995
|
|
|
|
somatic diversification of immunoglobulins
|
GO:0016445 |
43 |
0.994
|
|
|
|
interleukin 10 secretion
|
GO:0072608 |
4 |
0.994
|
|
|
|
immunoglobulin production
|
GO:0002377 |
73 |
0.993
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.993
|
|
|
|
regulation of immunoglobulin production
|
GO:0002637 |
42 |
0.992
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.992
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
61 |
0.992
|
|
|
|
chronic inflammatory response
|
GO:0002544 |
9 |
0.991
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.990
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.990
|
|
|
|
inflammatory response to antigenic stimulus
|
GO:0002437 |
30 |
0.988
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.988
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.988
|
|
|
|
regulation of dendritic cell chemotaxis
|
GO:2000508 |
1 |
0.987
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
52 |
0.987
|
|
|
|
eosinophil degranulation
|
GO:0043308 |
1 |
0.987
|
|
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
45 |
0.986
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.986
|
|
|
|
positive regulation of translational initiation
|
GO:0045948 |
4 |
0.985
|
|
|
|
regulation of cd4 positive alpha beta t cell activation
|
GO:2000514 |
24 |
0.985
|
|
|
|
mature dendritic cell differentiation
|
GO:0097029 |
3 |
0.984
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.983
|
|
|
|
b cell activation involved in immune response
|
GO:0002312 |
50 |
0.982
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.979
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.978
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.977
|
|
|
|
lymphocyte costimulation
|
GO:0031294 |
15 |
0.976
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.974
|
|
|
|
positive regulation of inflammatory response to antigenic stimulus
|
GO:0002863 |
11 |
0.974
|
|
|
|
regulation of b cell mediated immunity
|
GO:0002712 |
37 |
0.973
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.972
|
|
|
|
lymph node development
|
GO:0048535 |
18 |
0.972
|
|
|
|
cdc42 protein signal transduction
|
GO:0032488 |
0 |
0.972
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.972
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.971
|
|
|
|
positive regulation of b cell proliferation
|
GO:0030890 |
24 |
0.970
|
|
|
|
negative regulation of interleukin 5 production
|
GO:0032714 |
4 |
0.969
|
|
|
|
regulation of myeloid leukocyte mediated immunity
|
GO:0002886 |
25 |
0.967
|
|
|
|
somatic diversification of immune receptors via germline recombination within a single locus
|
GO:0002562 |
51 |
0.966
|
|
|
|
cytokine production involved in immune response
|
GO:0002367 |
34 |
0.964
|
|
|
|
defense response to gram positive bacterium
|
GO:0050830 |
50 |
0.962
|
|
|
|
negative regulation of growth of symbiont in host
|
GO:0044130 |
19 |
0.961
|
|
|
|
positive regulation of cd8 positive alpha beta t cell extravasation
|
GO:2000451 |
2 |
0.959
|
|
|
|
regulation of isotype switching
|
GO:0045191 |
22 |
0.959
|
|
|
|
positive regulation of myoblast differentiation
|
GO:0045663 |
8 |
0.958
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.958
|
|
|
|
regulation of isotype switching to igg isotypes
|
GO:0048302 |
10 |
0.957
|
|
|
|
isotype switching
|
GO:0045190 |
36 |
0.955
|
|
|
|
somatic cell dna recombination
|
GO:0016444 |
51 |
0.955
|
|
|
|
dendritic cell differentiation
|
GO:0097028 |
26 |
0.954
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.951
|
|
|
|
eosinophil activation
|
GO:0043307 |
1 |
0.950
|
|
|
|
regulation of mhc class ii biosynthetic process
|
GO:0045346 |
7 |
0.948
|
|
|
|
tumor necrosis factor mediated signaling pathway
|
GO:0033209 |
13 |
0.948
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.946
|
|
|
|
regulation of immune complex clearance by monocytes and macrophages
|
GO:0090264 |
2 |
0.945
|
|
|
|
positive regulation of myotube differentiation
|
GO:0010831 |
24 |
0.945
|
|
|
|
regulation of acute inflammatory response
|
GO:0002673 |
27 |
0.944
|
|
|
|
t helper cell differentiation
|
GO:0042093 |
28 |
0.942
|
|
|
|
organ or tissue specific immune response
|
GO:0002251 |
13 |
0.942
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
57 |
0.942
|
|
|
|
b cell mediated immunity
|
GO:0019724 |
71 |
0.942
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.939
|
|
|
|
regulation of chronic inflammatory response
|
GO:0002676 |
7 |
0.939
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.938
|
|
|
|
alpha beta t cell differentiation involved in immune response
|
GO:0002293 |
30 |
0.937
|
|
|
|
eosinophil activation involved in immune response
|
GO:0002278 |
1 |
0.935
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.934
|
|
|
|
positive regulation of chronic inflammatory response to antigenic stimulus
|
GO:0002876 |
2 |
0.930
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.928
|
|
|
|
regulation of fever generation
|
GO:0031620 |
6 |
0.928
|
|
|
|
alpha beta t cell proliferation
|
GO:0046633 |
21 |
0.928
|
|
|
|
tyrosine phosphorylation of stat1 protein
|
GO:0042508 |
3 |
0.927
|
|
|
|
regulation of regulated secretory pathway
|
GO:1903305 |
20 |
0.924
|
|
|
|
chronic inflammatory response to antigenic stimulus
|
GO:0002439 |
3 |
0.923
|
|
|
|
cd4 positive alpha beta t cell cytokine production
|
GO:0035743 |
4 |
0.922
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.922
|
|
|
|
regulation of translational initiation by iron
|
GO:0006447 |
2 |
0.920
|
|
|
|
growth of symbiont involved in interaction with host
|
GO:0044116 |
23 |
0.919
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.917
|
|
|
|
t cell costimulation
|
GO:0031295 |
14 |
0.916
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.913
|
|
|
|
positive regulation of regulatory t cell differentiation
|
GO:0045591 |
4 |
0.910
|
|
|
|
t helper 2 cell cytokine production
|
GO:0035745 |
4 |
0.909
|
|
|
|
antibacterial peptide production
|
GO:0002778 |
2 |
0.908
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.906
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.903
|
|
|
|
regulation of cd4 positive alpha beta t cell differentiation
|
GO:0043370 |
21 |
0.900
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.897
|
|
|
|
positive regulation of monocyte chemotaxis
|
GO:0090026 |
2 |
0.897
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.896
|
|
|
|
b cell proliferation
|
GO:0042100 |
53 |
0.896
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.894
|
|
|
|
regulation of fever generation by regulation of prostaglandin secretion
|
GO:0071810 |
2 |
0.893
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.889
|
|
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
81 |
0.887
|
|
|
|
cytokine production involved in inflammatory response
|
GO:0002534 |
9 |
0.887
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.887
|
|
|
|
regulation of cytokine production involved in immune response
|
GO:0002718 |
26 |
0.884
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.882
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.882
|
|
|
|
regulation of alpha beta t cell proliferation
|
GO:0046640 |
18 |
0.879
|
|
|
|
fever generation
|
GO:0001660 |
7 |
0.878
|
|
|
|
immune complex clearance
|
GO:0002434 |
2 |
0.877
|
|
|
|
myeloid dendritic cell differentiation
|
GO:0043011 |
16 |
0.868
|
|
|
|
positive regulation of syncytium formation by plasma membrane fusion
|
GO:0060143 |
17 |
0.867
|
|
|
|
antibacterial peptide secretion
|
GO:0002779 |
1 |
0.864
|
|
|
|
regulation of type 2 immune response
|
GO:0002828 |
18 |
0.861
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.857
|
|
|
|
regulation of b cell proliferation
|
GO:0030888 |
39 |
0.856
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.856
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.854
|
|
|
|
calcium ion transport into cytosol
|
GO:0060402 |
48 |
0.851
|
|
|
|
isotype switching to ige isotypes
|
GO:0048289 |
7 |
0.850
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.849
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.846
|
|
|
|
positive regulation of response to wounding
|
GO:1903036 |
66 |
0.846
|
|
|
|
regulation of monocyte extravasation
|
GO:2000437 |
2 |
0.845
|
|
|
|
positive regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903557 |
31 |
0.843
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.842
|
|
|
|
cd4 positive cd25 positive alpha beta regulatory t cell differentiation
|
GO:0002361 |
4 |
0.842
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.841
|
|
|
|
positive regulation of immunological synapse formation
|
GO:2000522 |
1 |
0.839
|
|
|
|
positive regulation of t cell receptor signaling pathway
|
GO:0050862 |
4 |
0.839
|
|
|
|
t cell selection
|
GO:0045058 |
34 |
0.838
|
|
|
|
chemokine mediated signaling pathway
|
GO:0070098 |
17 |
0.838
|
|
|
|
positive regulation of t cell costimulation
|
GO:2000525 |
2 |
0.837
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.834
|
|
|
|
regulation of immunoglobulin mediated immune response
|
GO:0002889 |
37 |
0.834
|
|
|
|
regulation of interleukin 10 secretion
|
GO:2001179 |
4 |
0.832
|
|
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
41 |
0.829
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.828
|
|
|
|
positive regulation of immunoglobulin production
|
GO:0002639 |
28 |
0.826
|
|
|
|
regulation of symbiosis encompassing mutualism through parasitism
|
GO:0043903 |
52 |
0.826
|
|
|
|
growth involved in symbiotic interaction
|
GO:0044110 |
23 |
0.826
|
|
|
|
positive regulation of chemotaxis
|
GO:0050921 |
38 |
0.823
|
|
|
|
alpha beta t cell lineage commitment
|
GO:0002363 |
7 |
0.821
|
|
|
|
positive regulation of tyrosine phosphorylation of stat protein
|
GO:0042531 |
15 |
0.819
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.811
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.811
|
|
|
|
regulation of monocyte chemotaxis
|
GO:0090025 |
3 |
0.810
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.810
|
|
|
|
response to amino acid
|
GO:0043200 |
37 |
0.803
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.802
|
|
|
|
regulation of myotube differentiation
|
GO:0010830 |
62 |
0.802
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.802
|
|
|
|
lymphocyte migration
|
GO:0072676 |
26 |
0.799
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.795
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
65 |
0.791
|
|
|
|
positive regulation of translational initiation by iron
|
GO:0045994 |
2 |
0.790
|
|
|
|
response to interferon gamma
|
GO:0034341 |
34 |
0.785
|
|
|
|
inflammatory cell apoptotic process
|
GO:0006925 |
11 |
0.784
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.783
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.782
|
|
|
|
regulation of corticotropin releasing hormone secretion
|
GO:0043397 |
2 |
0.781
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.781
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
40 |
0.779
|
|
|
|
tyrosine phosphorylation of stat protein
|
GO:0007260 |
23 |
0.773
|
|
|
|
cd4 positive alpha beta t cell lineage commitment
|
GO:0043373 |
6 |
0.772
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
83 |
0.772
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.771
|
|
|
|
positive regulation of tyrosine phosphorylation of stat1 protein
|
GO:0042511 |
1 |
0.771
|
|
|
|
activation of jun kinase activity
|
GO:0007257 |
15 |
0.771
|
|
|
|
positive regulation of fever generation by positive regulation of prostaglandin secretion
|
GO:0071812 |
2 |
0.768
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.767
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.763
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
64 |
0.763
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.760
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.757
|
|
|
|
helper t cell chemotaxis
|
GO:0035704 |
1 |
0.751
|
|
|
|
tyrosine phosphorylation of stat5 protein
|
GO:0042506 |
9 |
0.749
|
|
|
|
negative regulation of interleukin 5 secretion
|
GO:2000663 |
1 |
0.748
|
|
|
|
positive regulation of acute inflammatory response
|
GO:0002675 |
16 |
0.746
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.743
|
|
|
|
negative regulation of interleukin 2 biosynthetic process
|
GO:0045085 |
3 |
0.742
|
|
|
|
t helper 17 cell differentiation
|
GO:0072539 |
7 |
0.739
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.739
|
|
|
|
positive regulation of b cell activation
|
GO:0050871 |
49 |
0.738
|
|
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
61 |
0.737
|
|
|
|
positive regulation of monocyte extravasation
|
GO:2000439 |
1 |
0.737
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.735
|
|
|
|
positive regulation of immunoglobulin mediated immune response
|
GO:0002891 |
26 |
0.734
|
|
|
|
negative regulation of adaptive immune response
|
GO:0002820 |
25 |
0.733
|
|
|
|
positive regulation of muscle cell differentiation
|
GO:0051149 |
39 |
0.731
|
|
|
|
regulation of immunoglobulin secretion
|
GO:0051023 |
12 |
0.725
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.725
|
|
|
|
regulation of syncytium formation by plasma membrane fusion
|
GO:0060142 |
23 |
0.724
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.723
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.721
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.717
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.714
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.712
|
|
|
|
regulation of translational initiation
|
GO:0006446 |
15 |
0.711
|
|
|
|
regulation of tumor necrosis factor biosynthetic process
|
GO:0042534 |
10 |
0.710
|
|
|
|
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002823 |
23 |
0.710
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.707
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.707
|
|
|
|
positive regulation of mhc class ii biosynthetic process
|
GO:0045348 |
4 |
0.707
|
|
|
|
regulation of t helper 17 cell differentiation
|
GO:2000319 |
2 |
0.706
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.704
|
|
|
|
positive regulation of t helper 1 cell differentiation
|
GO:0045627 |
4 |
0.697
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.692
|
|
|
|
t helper 2 cell differentiation
|
GO:0045064 |
12 |
0.692
|
|
|
|
immune complex clearance by monocytes and macrophages
|
GO:0002436 |
2 |
0.691
|
|
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
39 |
0.683
|
|
|
|
cellular response to amino acid stimulus
|
GO:0071230 |
29 |
0.682
|
|
|
|
positive regulation of prostaglandin secretion
|
GO:0032308 |
5 |
0.679
|
|
|
|
t helper cell lineage commitment
|
GO:0002295 |
6 |
0.679
|
|
|
|
mammary gland lobule development
|
GO:0061377 |
22 |
0.673
|
|
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.672
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.672
|
|
|
|
positive regulation of inflammatory response
|
GO:0050729 |
47 |
0.672
|
|
|
|
positive regulation of activated t cell proliferation
|
GO:0042104 |
8 |
0.671
|
|
|
|
positive regulation of macrophage activation
|
GO:0043032 |
10 |
0.669
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.666
|
|
|
|
positive regulation of t cell chemotaxis
|
GO:0010820 |
5 |
0.665
|
|
|
|
negative regulation of macrophage apoptotic process
|
GO:2000110 |
3 |
0.663
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.662
|
|
|
|
regulation of cd8 positive alpha beta t cell extravasation
|
GO:2000449 |
3 |
0.659
|
|
|
|
cellular response to molecule of fungal origin
|
GO:0071226 |
2 |
0.659
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.658
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.657
|
|
|
|
regulation of t helper 1 cell differentiation
|
GO:0045625 |
7 |
0.656
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.644
|
|
|
|
interleukin 18 mediated signaling pathway
|
GO:0035655 |
2 |
0.644
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.643
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.640
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.639
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.634
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.627
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.627
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.626
|
|
|
|
positive regulation of t cell extravasation
|
GO:2000409 |
2 |
0.625
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.621
|
|
|
|
modification of morphology or physiology of other organism involved in symbiotic interaction
|
GO:0051817 |
16 |
0.619
|
|
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
42 |
0.615
|
|
|
|
interleukin 6 production
|
GO:0032635 |
58 |
0.614
|
|
|
|
positive regulation of jak stat cascade
|
GO:0046427 |
22 |
0.611
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.610
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.607
|
|
|
|
regulation of eosinophil degranulation
|
GO:0043309 |
1 |
0.606
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.605
|
|
|
|
production of molecular mediator involved in inflammatory response
|
GO:0002532 |
21 |
0.601
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.600
|
|
|
|
myeloid leukocyte mediated immunity
|
GO:0002444 |
42 |
0.597
|
|
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
70 |
0.597
|
|
|
|
dendrite regeneration
|
GO:0031104 |
1 |
0.596
|
|
|
|
myeloid cell activation involved in immune response
|
GO:0002275 |
34 |
0.590
|
|
|
|
t helper 17 cell chemotaxis
|
GO:0035705 |
1 |
0.590
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.588
|
|
|
|
growth of symbiont in host
|
GO:0044117 |
23 |
0.587
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.586
|
|
|
|
negative regulation of myoblast differentiation
|
GO:0045662 |
18 |
0.584
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.583
|
|
|
|
microglial cell activation involved in immune response
|
GO:0002282 |
1 |
0.583
|
|
|
|
translational initiation
|
GO:0006413 |
24 |
0.580
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.578
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.574
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
83 |
0.564
|
|
|
|
regulation of hypersensitivity
|
GO:0002883 |
10 |
0.559
|
|
|
|
regulation of tyrosine phosphorylation of stat1 protein
|
GO:0042510 |
2 |
0.556
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.554
|
|
|
|
t cell differentiation involved in immune response
|
GO:0002292 |
30 |
0.553
|
|
|
|
t cell migration
|
GO:0072678 |
19 |
0.553
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.552
|
|
|
|
stimulatory c type lectin receptor signaling pathway
|
GO:0002223 |
2 |
0.552
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.551
|
|
|
|
response to protozoan
|
GO:0001562 |
28 |
0.550
|
|
|
|
regulation of interleukin 2 production
|
GO:0032663 |
28 |
0.549
|
|
|
|
positive regulation of hypersensitivity
|
GO:0002885 |
7 |
0.547
|
|
|
|
regulation of t cell extravasation
|
GO:2000407 |
3 |
0.546
|
|
|
|
regulation of t helper cell differentiation
|
GO:0045622 |
14 |
0.546
|
|
|
|
t cell extravasation
|
GO:0072683 |
4 |
0.542
|
|
|
|
lipopolysaccharide mediated signaling pathway
|
GO:0031663 |
25 |
0.541
|
|
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
30 |
0.539
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
53 |
0.538
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.538
|
|
|
|
positive regulation of osteoclast development
|
GO:2001206 |
3 |
0.535
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.534
|
|
|
|
positive regulation of t cell migration
|
GO:2000406 |
10 |
0.533
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.527
|
|
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.527
|
|
|
|
negative regulation of interleukin 10 secretion
|
GO:2001180 |
2 |
0.526
|
|
|
|
regulation of lymphocyte migration
|
GO:2000401 |
14 |
0.524
|
|
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
21 |
0.520
|
|
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
32 |
0.519
|
|
|
|
thymic t cell selection
|
GO:0045061 |
22 |
0.515
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.513
|
|
|
|
osteoclast proliferation
|
GO:0002158 |
4 |
0.512
|
|
|
|
positive regulation of organic acid transport
|
GO:0032892 |
11 |
0.510
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
81 |
0.507
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.507
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.507
|
|
|
|
natural killer cell mediated cytotoxicity
|
GO:0042267 |
29 |
0.505
|
|
|
|
cd4 positive or cd8 positive alpha beta t cell lineage commitment
|
GO:0043369 |
8 |
0.504
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.504
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.503
|
|
|
|
regulation of alpha beta t cell differentiation
|
GO:0046637 |
35 |
0.501
|
|
|
|
defense response to gram negative bacterium
|
GO:0050829 |
28 |
0.501
|
|
|
|
regulated secretory pathway
|
GO:0045055 |
32 |
0.500
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.499
|
|
|
|
interleukin 13 secretion
|
GO:0072611 |
2 |
0.499
|
|
|
|
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation
|
GO:2000526 |
1 |
0.498
|
|
|
|
response to alcohol
|
GO:0097305 |
48 |
0.497
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.496
|
|
|
|
regulation of mast cell degranulation
|
GO:0043304 |
16 |
0.495
|
|
|
|
type 2 immune response
|
GO:0042092 |
23 |
0.493
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.489
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
29 |
0.488
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.482
|
|
|
|
positive regulation of acute inflammatory response to antigenic stimulus
|
GO:0002866 |
7 |
0.482
|
|
|
|
regulation of interleukin 13 secretion
|
GO:2000665 |
2 |
0.481
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
46 |
0.481
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
61 |
0.478
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.475
|
|
|
|
positive regulation of oligodendrocyte differentiation
|
GO:0048714 |
9 |
0.475
|
|
|
|
t helper 17 cell lineage commitment
|
GO:0072540 |
4 |
0.474
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.469
|
|
|
|
programmed necrotic cell death
|
GO:0097300 |
28 |
0.465
|
|
|
|
regulation of toll like receptor 2 signaling pathway
|
GO:0034135 |
3 |
0.464
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.463
|
|
|
|
humoral immune response
|
GO:0006959 |
57 |
0.461
|
|
|
|
lymphocyte chemotaxis
|
GO:0048247 |
10 |
0.459
|
|
|
|
regulation of t cell costimulation
|
GO:2000523 |
2 |
0.456
|
|
|
|
positive regulation of lipid transport
|
GO:0032370 |
22 |
0.454
|
|
|
|
regulation of interleukin 6 production
|
GO:0032675 |
55 |
0.453
|
|
|
|
modification of morphology or physiology of other organism
|
GO:0035821 |
18 |
0.450
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.448
|
|
|
|
positive regulation of dendritic cell chemotaxis
|
GO:2000510 |
1 |
0.447
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
61 |
0.444
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
74 |
0.444
|
|
|
|
granulocyte activation
|
GO:0036230 |
10 |
0.441
|
|
|
|
positive regulation of immune complex clearance by monocytes and macrophages
|
GO:0090265 |
2 |
0.438
|
|
|
|
regulation of regulatory t cell differentiation
|
GO:0045589 |
7 |
0.438
|
|
|
|
interleukin 17 production
|
GO:0032620 |
11 |
0.437
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
71 |
0.436
|
|
|
|
t cell chemotaxis
|
GO:0010818 |
6 |
0.435
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.432
|
|
|
|
regulation of interleukin 1 production
|
GO:0032652 |
26 |
0.431
|
|
|
|
regulation of interleukin 12 production
|
GO:0032655 |
30 |
0.428
|
|
|
|
cell killing
|
GO:0001906 |
67 |
0.427
|
|
|
|
regulation of antigen processing and presentation
|
GO:0002577 |
10 |
0.424
|
|
|
|
granulocyte chemotaxis
|
GO:0071621 |
39 |
0.424
|
|
|
|
mast cell activation
|
GO:0045576 |
27 |
0.420
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.418
|
|
|
|
regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001239 |
26 |
0.417
|
|
|
|
negative regulation of alpha beta t cell activation
|
GO:0046636 |
18 |
0.414
|
|
|
|
positive regulation of lymphocyte mediated immunity
|
GO:0002708 |
62 |
0.414
|
|
|
|
positive regulation of fever generation
|
GO:0031622 |
6 |
0.413
|
|
|
|
regulation of tyrosine phosphorylation of stat protein
|
GO:0042509 |
20 |
0.411
|
|
|
|
negative regulation of chronic inflammatory response
|
GO:0002677 |
3 |
0.410
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.409
|
|
|
|
hypersensitivity
|
GO:0002524 |
10 |
0.404
|
|
|
|
regulation of t helper 1 type immune response
|
GO:0002825 |
17 |
0.401
|
|
|
|
negative regulation of interleukin 13 secretion
|
GO:2000666 |
1 |
0.401
|
|
|
|
response to interleukin 1
|
GO:0070555 |
11 |
0.399
|
|
|
|
positive regulation of behavior
|
GO:0048520 |
40 |
0.398
|
|
|
|
leukocyte degranulation
|
GO:0043299 |
27 |
0.398
|
|
|
|
t cell activation involved in immune response
|
GO:0002286 |
43 |
0.396
|
|
|
|
regulation of interleukin 5 secretion
|
GO:2000662 |
2 |
0.396
|
|
|
|
t helper 1 type immune response
|
GO:0042088 |
25 |
0.394
|
|
|
|
regulation of leukocyte degranulation
|
GO:0043300 |
20 |
0.391
|
|
|
|
alpha beta t cell activation involved in immune response
|
GO:0002287 |
31 |
0.390
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.389
|
|
|
|
regulation of interleukin 10 production
|
GO:0032653 |
21 |
0.387
|
|
|
|
positive regulation of interleukin 12 production
|
GO:0032735 |
21 |
0.385
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.385
|
|
|
|
negative regulation of odontogenesis of dentin containing tooth
|
GO:0042489 |
1 |
0.385
|
|
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.382
|
|
|
|
protein oligomerization
|
GO:0051259 |
67 |
0.381
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.380
|
|
|
|
negative regulation of cd4 positive alpha beta t cell differentiation
|
GO:0043371 |
9 |
0.379
|
|
|
|
t cell lineage commitment
|
GO:0002360 |
13 |
0.377
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.376
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.375
|
|
|
|
dephosphorylation
|
GO:0016311 |
129 |
0.370
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.368
|
|
|
|
positive regulation of activation of membrane attack complex
|
GO:0001970 |
2 |
0.367
|
|
|
|
innate immune response activating cell surface receptor signaling pathway
|
GO:0002220 |
4 |
0.364
|
|
|
|
monocyte extravasation
|
GO:0035696 |
2 |
0.363
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
36 |
0.361
|
|
|
|
t helper 1 cell lineage commitment
|
GO:0002296 |
2 |
0.361
|
|
|
|
positive regulation of alpha beta t cell activation
|
GO:0046635 |
39 |
0.360
|
|
|
|
regulation of cdc42 protein signal transduction
|
GO:0032489 |
5 |
0.358
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.355
|
|
|
|
negative regulation of leukocyte proliferation
|
GO:0070664 |
46 |
0.355
|
|
|
|
regulation of mast cell activation
|
GO:0033003 |
21 |
0.354
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.352
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.350
|
|
|
|
negative thymic t cell selection
|
GO:0045060 |
12 |
0.350
|
|
|
|
interleukin 12 production
|
GO:0032615 |
32 |
0.348
|
|
|
|
interleukin 5 secretion
|
GO:0072603 |
2 |
0.347
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.345
|
|
|
|
positive regulation of antigen processing and presentation
|
GO:0002579 |
10 |
0.345
|
|
|
|
regulation of fatty acid transport
|
GO:2000191 |
10 |
0.343
|
|
|
|
positive regulation of hematopoietic stem cell migration
|
GO:2000473 |
1 |
0.341
|
|
|
|
regulation of osteoclast differentiation
|
GO:0045670 |
36 |
0.338
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.334
|
|
|
|
prostaglandin transport
|
GO:0015732 |
7 |
0.332
|
|
|
|
regulation of skeletal muscle fiber development
|
GO:0048742 |
36 |
0.331
|
|
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.330
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.329
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
57 |
0.326
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.322
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.320
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.318
|
|
|
|
leukocyte homeostasis
|
GO:0001776 |
79 |
0.316
|
|
|
|
cd8 positive alpha beta t cell extravasation
|
GO:0035697 |
3 |
0.313
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.311
|
|
|
|
negative regulation of innate immune response
|
GO:0045824 |
17 |
0.311
|
|
|
|
negative regulation of inflammatory response
|
GO:0050728 |
61 |
0.310
|
|
|
|
regulation of t helper 1 cell cytokine production
|
GO:2000554 |
1 |
0.309
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.306
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001240 |
16 |
0.306
|
|
|
|
positive regulation of peptide hormone secretion
|
GO:0090277 |
31 |
0.303
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.302
|
|
|
|
macrophage activation
|
GO:0042116 |
27 |
0.299
|
|
|
|
regulation of glial cell differentiation
|
GO:0045685 |
41 |
0.297
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.295
|
|
|
|
response to bacterial lipoprotein
|
GO:0032493 |
4 |
0.294
|
|
|
|
positive t cell selection
|
GO:0043368 |
23 |
0.294
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
88 |
0.294
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
26 |
0.293
|
|
|
|
regulation of anion transport
|
GO:0044070 |
27 |
0.292
|
|
|
|
cd4 positive alpha beta t cell differentiation involved in immune response
|
GO:0002294 |
28 |
0.290
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.289
|
|
|
|
positive regulation of isotype switching to ige isotypes
|
GO:0048295 |
4 |
0.288
|
|
|
|
regulation of dephosphorylation
|
GO:0035303 |
18 |
0.284
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.283
|
|
|
|
positive regulation of cd4 positive alpha beta t cell proliferation
|
GO:2000563 |
1 |
0.279
|
|
|
|
negative regulation of myeloid cell apoptotic process
|
GO:0033033 |
11 |
0.276
|
|
|
|
eosinophil mediated immunity
|
GO:0002447 |
1 |
0.276
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
97 |
0.274
|
|
|
|
negative regulation of myeloid leukocyte mediated immunity
|
GO:0002887 |
7 |
0.274
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
68 |
0.273
|
|
|
|
jak stat cascade
|
GO:0007259 |
42 |
0.273
|
|
|
|
positive regulation of neuron apoptotic process
|
GO:0043525 |
25 |
0.273
|
|
|
|
myd88 independent toll like receptor signaling pathway
|
GO:0002756 |
3 |
0.272
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.268
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.267
|
|
|
|
protein homooligomerization
|
GO:0051260 |
43 |
0.266
|
|
|
|
organ regeneration
|
GO:0031100 |
2 |
0.263
|
|
|
|
positive regulation of osteoclast differentiation
|
GO:0045672 |
15 |
0.260
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.258
|
|
|
|
mammary gland alveolus development
|
GO:0060749 |
22 |
0.258
|
|
|
|
corticotropin releasing hormone secretion
|
GO:0043396 |
2 |
0.258
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.256
|
|
|
|
natural killer cell activation
|
GO:0030101 |
44 |
0.254
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.253
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.253
|
|
|
|
positive regulation of type 2 immune response
|
GO:0002830 |
9 |
0.251
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.250
|
|
|
|
regulation of lymphocyte chemotaxis
|
GO:1901623 |
6 |
0.249
|
|
|
|
regulation of tolerance induction dependent upon immune response
|
GO:0002652 |
1 |
0.248
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.248
|
|
|
|
necroptotic process
|
GO:0070266 |
21 |
0.247
|
|
|
|
positive regulation of interleukin 2 production
|
GO:0032743 |
19 |
0.246
|
|
|
|
tolerance induction
|
GO:0002507 |
14 |
0.245
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.245
|
|
|
|
acute inflammatory response to antigenic stimulus
|
GO:0002438 |
12 |
0.245
|
|
|
|
cellular response to interferon gamma
|
GO:0071346 |
25 |
0.243
|
|
|
|
regulation of icosanoid secretion
|
GO:0032303 |
8 |
0.242
|
|
|
|
t helper 1 cell cytokine production
|
GO:0035744 |
1 |
0.242
|
|
|
|
detection of molecule of bacterial origin
|
GO:0032490 |
2 |
0.236
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.236
|
|
|
|
negative regulation of b cell proliferation
|
GO:0030889 |
13 |
0.235
|
|
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
52 |
0.233
|
|
|
|
cholesterol metabolic process
|
GO:0008203 |
56 |
0.232
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.232
|
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.230
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.229
|
|
|
|
antibacterial peptide biosynthetic process
|
GO:0002780 |
2 |
0.228
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.228
|
|
