Mus musculus

85 known processes

Ift80

intraflagellar transport 80 homolog (Chlamydomonas)

(Aliases: 4921524P20Rik,Wdr56,mKIAA1374)

Ift80 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cilium assembly GO:0042384 81 0.954
cilium morphogenesis GO:0060271 102 0.947
intraciliary transport GO:0042073 9 0.645
organelle assembly GO:0070925 177 0.544
cellular component assembly involved in morphogenesis GO:0010927 139 0.540
intraciliary retrograde transport GO:0035721 3 0.382
microtubule based process GO:0007017 236 0.212
smoothened signaling pathway GO:0007224 105 0.202
cytoskeleton dependent intracellular transport GO:0030705 50 0.189
microtubule cytoskeleton organization GO:0000226 157 0.143
microtubule based movement GO:0007018 84 0.131
regulation of cilium assembly GO:1902017 7 0.129
protein maturation GO:0051604 176 0.114
microtubule based transport GO:0010970 50 0.091
neural tube development GO:0021915 160 0.090
sensory organ morphogenesis GO:0090596 242 0.075
Zebrafish
regionalization GO:0003002 337 0.070
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.067
dna metabolic process GO:0006259 303 0.065
epithelial cilium movement GO:0003351 12 0.064
regulation of microtubule based process GO:0032886 52 0.060
mitotic cell cycle process GO:1903047 159 0.058
positive regulation of cellular amine metabolic process GO:0033240 5 0.055
regulation of cellular amine metabolic process GO:0033238 20 0.054
camera type eye development GO:0043010 266 0.053
Zebrafish
fat cell differentiation GO:0045444 160 0.053
regulation of cellular amino acid metabolic process GO:0006521 5 0.049
muscle cell differentiation GO:0042692 261 0.049
amine metabolic process GO:0009308 45 0.049
regulation of smoothened signaling pathway GO:0008589 58 0.047
eye photoreceptor cell differentiation GO:0001754 41 0.046
telencephalon development GO:0021537 186 0.044
spermatogenesis GO:0007283 284 0.044
forebrain development GO:0030900 302 0.043
axoneme assembly GO:0035082 15 0.042
regulation of protein maturation GO:1903317 96 0.042
photoreceptor cell differentiation GO:0046530 52 0.042
mitotic cell cycle GO:0000278 195 0.040
organelle localization GO:0051640 179 0.039
cellular amine metabolic process GO:0044106 44 0.039
cellular response to dna damage stimulus GO:0006974 207 0.039
spermatid development GO:0007286 108 0.039
neural tube formation GO:0001841 108 0.038
cellular macromolecule catabolic process GO:0044265 206 0.038
limb morphogenesis GO:0035108 149 0.037
establishment of organelle localization GO:0051656 122 0.037
protein processing GO:0016485 163 0.037
cellular ketone metabolic process GO:0042180 84 0.036
germ cell development GO:0007281 185 0.036
nonmotile primary cilium assembly GO:0035058 8 0.035
protein catabolic process GO:0030163 221 0.035
retina development in camera type eye GO:0060041 119 0.034
Zebrafish
regulation of protein processing GO:0070613 96 0.034
embryonic appendage morphogenesis GO:0035113 126 0.034
organelle fission GO:0048285 170 0.032
tube formation GO:0035148 140 0.032
eye photoreceptor cell development GO:0042462 31 0.031
spermatid differentiation GO:0048515 115 0.031
microtubule organizing center organization GO:0031023 28 0.031
spinal cord development GO:0021510 81 0.031
nuclear division GO:0000280 158 0.031
spinal cord dorsal ventral patterning GO:0021513 23 0.031
nucleotide metabolic process GO:0009117 332 0.031
cellular amino acid metabolic process GO:0006520 103 0.030
male gamete generation GO:0048232 285 0.030
regulation of organelle organization GO:0033043 289 0.030
epithelial tube formation GO:0072175 130 0.029
regulation of cell projection organization GO:0031344 206 0.029
embryonic digit morphogenesis GO:0042733 56 0.028
macromolecule catabolic process GO:0009057 281 0.028
photoreceptor cell development GO:0042461 40 0.028
epithelial tube morphogenesis GO:0060562 303 0.028
proteasomal protein catabolic process GO:0010498 98 0.028
protein modification by small protein conjugation GO:0032446 187 0.028
regulation of cell cycle GO:0051726 281 0.027
appendage morphogenesis GO:0035107 149 0.027
protein ubiquitination GO:0016567 171 0.027
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.027
embryonic limb morphogenesis GO:0030326 126 0.026
dna templated transcriptional preinitiation complex assembly GO:0070897 4 0.026
cellular protein catabolic process GO:0044257 155 0.026
urogenital system development GO:0001655 261 0.025
regulation of cellular ketone metabolic process GO:0010565 66 0.025
modification dependent protein catabolic process GO:0019941 133 0.025
modification dependent macromolecule catabolic process GO:0043632 133 0.025
heterocycle catabolic process GO:0046700 280 0.025
sensory perception of sound GO:0007605 97 0.024
cytoplasmic transport GO:0016482 234 0.024
protein modification by small protein conjugation or removal GO:0070647 207 0.024
regulation of fat cell differentiation GO:0045598 81 0.024
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.024
carbohydrate homeostasis GO:0033500 128 0.024
retina morphogenesis in camera type eye GO:0060042 45 0.023
Zebrafish
purine containing compound metabolic process GO:0072521 311 0.023
sensory perception GO:0007600 245 0.023
cellular response to hormone stimulus GO:0032870 150 0.022
transmembrane transport GO:0055085 412 0.022
regulation of cell cycle process GO:0010564 160 0.022
cell division GO:0051301 120 0.022
apoptotic signaling pathway GO:0097190 306 0.022
hematopoietic progenitor cell differentiation GO:0002244 143 0.021
ear development GO:0043583 200 0.021
glucose homeostasis GO:0042593 128 0.021
epithelial cell proliferation GO:0050673 174 0.021
endomembrane system organization GO:0010256 147 0.021
skin development GO:0043588 220 0.020
adult behavior GO:0030534 135 0.020
skeletal system development GO:0001501 356 0.020
metencephalon development GO:0022037 89 0.020
aromatic compound catabolic process GO:0019439 286 0.020
nucleobase containing small molecule metabolic process GO:0055086 352 0.020
limb development GO:0060173 166 0.020
appendage development GO:0048736 166 0.020
ribonucleoside metabolic process GO:0009119 245 0.020
cellular nitrogen compound catabolic process GO:0044270 280 0.020
organic cyclic compound catabolic process GO:1901361 295 0.020
respiratory system development GO:0060541 190 0.019
spinal cord patterning GO:0021511 25 0.019
negative regulation of protein metabolic process GO:0051248 282 0.019
renal system development GO:0072001 225 0.019
centrosome organization GO:0051297 26 0.019
organophosphate catabolic process GO:0046434 232 0.019
primary neural tube formation GO:0014020 95 0.019
regulation of protein catabolic process GO:0042176 108 0.019
purine nucleoside metabolic process GO:0042278 241 0.019
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.019
meiotic nuclear division GO:0007126 115 0.019
negative regulation of cell proliferation GO:0008285 296 0.019
regulation of microtubule cytoskeleton organization GO:0070507 37 0.018
muscle tissue development GO:0060537 308 0.018
ribose phosphate metabolic process GO:0019693 291 0.018
negative regulation of molecular function GO:0044092 258 0.018
methylation GO:0032259 134 0.018
b cell activation GO:0042113 161 0.018
morphogenesis of embryonic epithelium GO:0016331 159 0.018
nucleoside catabolic process GO:0009164 206 0.018
cerebellum development GO:0021549 77 0.018
embryonic organ morphogenesis GO:0048562 276 0.018
lymphocyte differentiation GO:0030098 242 0.018
regulation of cell activation GO:0050865 289 0.018
hindbrain development GO:0030902 128 0.018
centrosome cycle GO:0007098 23 0.017
intracellular protein transport GO:0006886 204 0.017
protein localization to organelle GO:0033365 185 0.017
nucleoside phosphate metabolic process GO:0006753 338 0.017
purine nucleoside triphosphate catabolic process GO:0009146 203 0.017
chromosome organization involved in meiosis GO:0070192 39 0.017
cellular homeostasis GO:0019725 240 0.017
determination of left right symmetry GO:0007368 80 0.017
cation transmembrane transport GO:0098655 266 0.017
sensory perception of mechanical stimulus GO:0050954 107 0.017
leukocyte differentiation GO:0002521 342 0.016
purine nucleotide catabolic process GO:0006195 211 0.016
response to radiation GO:0009314 165 0.016
negative regulation of nervous system development GO:0051961 156 0.016
lymphocyte mediated immunity GO:0002449 139 0.016
meiotic cell cycle GO:0051321 122 0.016
nucleoside triphosphate metabolic process GO:0009141 230 0.016
chemotaxis GO:0006935 247 0.016
Worm
positive regulation of cell development GO:0010720 237 0.016
carbohydrate derivative catabolic process GO:1901136 231 0.016
glycosyl compound metabolic process GO:1901657 246 0.015
cation transport GO:0006812 399 0.015
regulation of proteolysis GO:0030162 164 0.015
photoreceptor cell maintenance GO:0045494 19 0.015
chromatin modification GO:0016568 187 0.015
chromatin organization GO:0006325 206 0.015
meiotic cell cycle process GO:1903046 77 0.015
epithelial cell development GO:0002064 159 0.015
cell type specific apoptotic process GO:0097285 268 0.015
nitrogen compound transport GO:0071705 271 0.015
membrane organization GO:0061024 245 0.015
anatomical structure homeostasis GO:0060249 145 0.015
response to oxidative stress GO:0006979 123 0.015
immune effector process GO:0002252 321 0.015
response to light stimulus GO:0009416 135 0.015
purine nucleoside triphosphate metabolic process GO:0009144 226 0.015
nucleoside metabolic process GO:0009116 246 0.015
regulation of microtubule polymerization or depolymerization GO:0031110 20 0.015
neural tube patterning GO:0021532 43 0.014
positive regulation of nervous system development GO:0051962 221 0.014
regulation of epithelial cell proliferation GO:0050678 141 0.014
regulation of intracellular transport GO:0032386 159 0.014
rhythmic process GO:0048511 174 0.014
purine ribonucleotide metabolic process GO:0009150 290 0.014
ubiquitin dependent protein catabolic process GO:0006511 129 0.014
regulation of apoptotic signaling pathway GO:2001233 197 0.014
pancreas development GO:0031016 57 0.014
regulation of cellular catabolic process GO:0031329 242 0.014
negative regulation of cellular component organization GO:0051129 194 0.014
small gtpase mediated signal transduction GO:0007264 97 0.014
digestive tract morphogenesis GO:0048546 147 0.014
response to insulin GO:0032868 100 0.014
t cell activation GO:0042110 289 0.014
lung development GO:0030324 164 0.014
b cell differentiation GO:0030183 78 0.014
negative regulation of cellular protein metabolic process GO:0032269 247 0.014
negative regulation of cell development GO:0010721 169 0.014
inorganic ion transmembrane transport GO:0098660 234 0.014
positive regulation of cell cycle process GO:0090068 61 0.013
cilium movement GO:0003341 28 0.013
negative regulation of organelle organization GO:0010639 90 0.013
axonogenesis GO:0007409 274 0.013
notch signaling pathway GO:0007219 71 0.013
regulation of cellular component biogenesis GO:0044087 181 0.013
centrosome duplication GO:0051298 16 0.013
regulation of t cell activation GO:0050863 170 0.013
gastrulation GO:0007369 116 0.013
regulation of mitotic cell cycle phase transition GO:1901990 73 0.013
purine nucleotide metabolic process GO:0006163 302 0.013
regulation of mitotic cell cycle GO:0007346 126 0.013
sister chromatid segregation GO:0000819 20 0.013
regulation of cytoskeleton organization GO:0051493 122 0.013
regulation of neuron projection development GO:0010975 169 0.013
digestive tract development GO:0048565 190 0.013
peptide transport GO:0015833 133 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.012
divalent metal ion transport GO:0070838 172 0.012
cerebellar cortex development GO:0021695 48 0.012
cellular lipid metabolic process GO:0044255 323 0.012
nucleotide catabolic process GO:0009166 217 0.012
protein dna complex subunit organization GO:0071824 28 0.012
organonitrogen compound catabolic process GO:1901565 264 0.012
neural retina development GO:0003407 41 0.012
neuron death GO:0070997 154 0.012
purine ribonucleotide catabolic process GO:0009154 208 0.012
cellular response to gamma radiation GO:0071480 4 0.012
substantia nigra development GO:0021762 2 0.012
macromolecule methylation GO:0043414 120 0.012
spermatid nucleus differentiation GO:0007289 19 0.012
vesicle localization GO:0051648 86 0.012
cytoplasmic microtubule organization GO:0031122 14 0.012
microtubule polymerization or depolymerization GO:0031109 26 0.012
digestive system development GO:0055123 200 0.012
heart morphogenesis GO:0003007 178 0.012
mitotic nuclear division GO:0007067 48 0.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.012
olfactory learning GO:0008355 2 0.011
ribonucleotide catabolic process GO:0009261 208 0.011
regulation of neuron differentiation GO:0045664 281 0.011
peptide hormone secretion GO:0030072 109 0.011
ribonucleotide metabolic process GO:0009259 291 0.011
protein polymerization GO:0051258 57 0.011
gland development GO:0048732 330 0.011
positive regulation of smoothened signaling pathway GO:0045880 23 0.011
ras protein signal transduction GO:0007265 77 0.011
dna repair GO:0006281 107 0.011
cellular response to peptide hormone stimulus GO:0071375 92 0.011
cellular response to organonitrogen compound GO:0071417 145 0.011
nucleus organization GO:0006997 45 0.011
peptide secretion GO:0002790 114 0.011
negative regulation of intracellular signal transduction GO:1902532 167 0.011
response to peptide hormone GO:0043434 127 0.011
morphogenesis of a polarized epithelium GO:0001738 37 0.011
intrinsic apoptotic signaling pathway GO:0097193 132 0.011
regulation of secretion GO:0051046 274 0.011
regulation of lymphocyte differentiation GO:0045619 107 0.011
nucleoside monophosphate metabolic process GO:0009123 85 0.011
negative regulation of proteolysis GO:0045861 74 0.011
response to organonitrogen compound GO:0010243 246 0.011
multicellular organismal homeostasis GO:0048871 164 0.011
posttranscriptional regulation of gene expression GO:0010608 155 0.011
nucleocytoplasmic transport GO:0006913 139 0.011
neural tube closure GO:0001843 90 0.011
negative regulation of t helper 2 cell differentiation GO:0045629 4 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.011
cellular protein complex assembly GO:0043623 116 0.011
neuron apoptotic process GO:0051402 142 0.010
kidney development GO:0001822 213 0.010
response to extracellular stimulus GO:0009991 127 0.010
centriole assembly GO:0098534 6 0.010
ribonucleoside triphosphate catabolic process GO:0009203 199 0.010
positive regulation of lymphocyte activation GO:0051251 140 0.010
insulin secretion GO:0030073 89 0.010
negative regulation of cell cycle process GO:0010948 69 0.010
negative regulation of cell cycle GO:0045786 123 0.010
left right pattern formation GO:0060972 23 0.010
purine nucleoside catabolic process GO:0006152 205 0.010
ribonucleoside triphosphate metabolic process GO:0009199 220 0.010
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.010
sodium ion transport GO:0006814 73 0.010
negative regulation of apoptotic signaling pathway GO:2001234 104 0.010
developmental growth involved in morphogenesis GO:0060560 138 0.010
inorganic cation transmembrane transport GO:0098662 207 0.010
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.010
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.010
regulation of chromosome organization GO:0033044 83 0.010

Ift80 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.058
nervous system disease DOID:863 0 0.058
central nervous system disease DOID:331 0 0.027
retinal disease DOID:5679 0 0.019
sensory system disease DOID:0050155 0 0.019
eye and adnexa disease DOID:1492 0 0.019
eye disease DOID:5614 0 0.019
retinal degeneration DOID:8466 0 0.018
neurodegenerative disease DOID:1289 0 0.016
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
immune system disease DOID:2914 0 0.011
organ system cancer DOID:0050686 0 0.010