|
|
regulation of insulin receptor signaling pathway
|
GO:0046626 |
21 |
0.972
|
|
|
|
hexose metabolic process
|
GO:0019318 |
98 |
0.965
|
Mouse |
|
|
monosaccharide metabolic process
|
GO:0005996 |
106 |
0.942
|
Mouse |
|
|
regulation of polysaccharide metabolic process
|
GO:0032881 |
13 |
0.931
|
Mouse |
|
|
regulation of glucan biosynthetic process
|
GO:0010962 |
7 |
0.925
|
Mouse |
|
|
regulation of glycogen metabolic process
|
GO:0070873 |
13 |
0.878
|
Mouse |
|
|
glucose metabolic process
|
GO:0006006 |
92 |
0.793
|
Mouse |
|
|
glycogen metabolic process
|
GO:0005977 |
32 |
0.778
|
Mouse |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.768
|
|
|
|
positive regulation of glucose metabolic process
|
GO:0010907 |
21 |
0.755
|
Mouse |
|
|
carbohydrate biosynthetic process
|
GO:0016051 |
74 |
0.732
|
Mouse |
|
|
cellular polysaccharide metabolic process
|
GO:0044264 |
38 |
0.701
|
Mouse |
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.695
|
Zebrafish |
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.688
|
Mouse |
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.681
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
119 |
0.671
|
Mouse |
|
|
insulin like growth factor receptor signaling pathway
|
GO:0048009 |
21 |
0.663
|
Human Zebrafish |
|
|
negative regulation of insulin receptor signaling pathway
|
GO:0046627 |
14 |
0.659
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.650
|
|
|
|
energy reserve metabolic process
|
GO:0006112 |
39 |
0.649
|
Mouse |
|
|
gland development
|
GO:0048732 |
330 |
0.620
|
|
|
|
polysaccharide biosynthetic process
|
GO:0000271 |
20 |
0.619
|
Mouse |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.612
|
|
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.612
|
Fly |
|
|
epidermis development
|
GO:0008544 |
187 |
0.610
|
|
|
|
release of cytochrome c from mitochondria
|
GO:0001836 |
23 |
0.592
|
|
|
|
polysaccharide metabolic process
|
GO:0005976 |
39 |
0.575
|
Mouse |
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.566
|
|
|
|
regulation of carbohydrate biosynthetic process
|
GO:0043255 |
40 |
0.534
|
Mouse |
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.520
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.519
|
Rat Fly |
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.515
|
|
|
|
regulation of glucose metabolic process
|
GO:0010906 |
60 |
0.510
|
Mouse |
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.500
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.488
|
|
|
|
cellular glucan metabolic process
|
GO:0006073 |
32 |
0.480
|
Mouse |
|
|
insulin receptor signaling pathway
|
GO:0008286 |
49 |
0.480
|
Mouse Fly |
|
|
cation transport
|
GO:0006812 |
399 |
0.472
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.467
|
Human |
|
|
forebrain development
|
GO:0030900 |
302 |
0.461
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.455
|
Human Zebrafish Mouse Fly |
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.454
|
Worm Fly |
|
|
glycogen biosynthetic process
|
GO:0005978 |
14 |
0.453
|
Mouse |
|
|
ossification
|
GO:0001503 |
216 |
0.445
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.433
|
Mouse |
|
|
adult behavior
|
GO:0030534 |
135 |
0.426
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.424
|
Fly |
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.412
|
|
|
|
negative regulation of glycogen biosynthetic process
|
GO:0045719 |
1 |
0.406
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
42 |
0.403
|
Fly |
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.399
|
|
|
|
negative regulation of release of cytochrome c from mitochondria
|
GO:0090201 |
6 |
0.395
|
|
|
|
central nervous system neuron differentiation
|
GO:0021953 |
162 |
0.386
|
Zebrafish |
|
|
wound healing
|
GO:0042060 |
157 |
0.385
|
Zebrafish |
|
|
gonad development
|
GO:0008406 |
141 |
0.374
|
Fly |
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.370
|
|
|
|
glucan biosynthetic process
|
GO:0009250 |
14 |
0.369
|
Mouse |
|
|
type i pneumocyte differentiation
|
GO:0060509 |
7 |
0.366
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.364
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.359
|
Mouse Fly |
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.353
|
Human |
|
|
regulation of generation of precursor metabolites and energy
|
GO:0043467 |
38 |
0.350
|
Mouse |
|
|
sensory perception of umami taste
|
GO:0050917 |
4 |
0.341
|
|
|
|
response to alkaloid
|
GO:0043279 |
34 |
0.341
|
Fly |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.337
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.335
|
Fly |
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.329
|
Human |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.327
|
|
|
|
myelination in peripheral nervous system
|
GO:0022011 |
19 |
0.315
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.313
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.311
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
86 |
0.302
|
Rat |
|
|
translation
|
GO:0006412 |
93 |
0.301
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.298
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.296
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
98 |
0.295
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.293
|
|
|
|
lung epithelium development
|
GO:0060428 |
37 |
0.290
|
|
|
|
lung cell differentiation
|
GO:0060479 |
30 |
0.290
|
|
|
|
mesodermal cell migration
|
GO:0008078 |
4 |
0.285
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.285
|
|
|
|
synapse organization
|
GO:0050808 |
125 |
0.284
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.283
|
|
|
|
regulation of release of cytochrome c from mitochondria
|
GO:0090199 |
11 |
0.279
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.278
|
|
|
|
negative regulation of cellular response to insulin stimulus
|
GO:1900077 |
16 |
0.276
|
|
|
|
proteoglycan biosynthetic process
|
GO:0030166 |
20 |
0.274
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.269
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.267
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.266
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.266
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
92 |
0.264
|
Mouse Fly |
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.263
|
|
|
|
positive regulation of cellular carbohydrate metabolic process
|
GO:0010676 |
29 |
0.261
|
Mouse |
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.261
|
Fly |
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.259
|
Fly |
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.259
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.256
|
Fly |
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.254
|
Worm Fly |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.250
|
Human Zebrafish |
|
|
renal system development
|
GO:0072001 |
225 |
0.248
|
|
|
|
glucose transport
|
GO:0015758 |
56 |
0.242
|
|
|
|
connective tissue development
|
GO:0061448 |
179 |
0.242
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.239
|
Human |
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.236
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.233
|
|
|
|
organelle assembly
|
GO:0070925 |
177 |
0.232
|
Worm |
|
|
retina development in camera type eye
|
GO:0060041 |
119 |
0.231
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
92 |
0.231
|
|
|
|
regulation of organ growth
|
GO:0046620 |
61 |
0.229
|
Fly |
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.226
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.226
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.224
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.224
|
Human |
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.220
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
78 |
0.220
|
Mouse Fly |
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.219
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.212
|
Zebrafish |
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.210
|
Worm |
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.210
|
Worm |
|
|
cerebellar granule cell precursor proliferation
|
GO:0021930 |
10 |
0.208
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.208
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.208
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.206
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.205
|
Fly |
|
|
response to insulin
|
GO:0032868 |
100 |
0.205
|
Mouse Fly |
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.202
|
Mouse Fly |
|
|
response to radiation
|
GO:0009314 |
165 |
0.201
|
|
|
|
regulation of cellular carbohydrate metabolic process
|
GO:0010675 |
75 |
0.200
|
Mouse |
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.199
|
|
|
|
steroid metabolic process
|
GO:0008202 |
119 |
0.196
|
Rat |
|
|
lung development
|
GO:0030324 |
164 |
0.195
|
|
|
|
kidney development
|
GO:0001822 |
213 |
0.193
|
|
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
75 |
0.192
|
Mouse |
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.192
|
|
|
|
germ line stem cell division
|
GO:0042078 |
2 |
0.192
|
Fly |
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.190
|
|
|
|
organ growth
|
GO:0035265 |
117 |
0.190
|
Fly |
|
|
regulation of protein catabolic process
|
GO:0042176 |
108 |
0.190
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.189
|
|
|
|
cartilage development
|
GO:0051216 |
140 |
0.189
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
53 |
0.188
|
|
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.186
|
Rat Worm |
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.185
|
|
|
|
regulation of steroid biosynthetic process
|
GO:0050810 |
26 |
0.185
|
Rat |
|
|
type ii pneumocyte differentiation
|
GO:0060510 |
7 |
0.184
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.182
|
|
|
|
carbohydrate homeostasis
|
GO:0033500 |
128 |
0.182
|
|
|
|
glucose import
|
GO:0046323 |
32 |
0.180
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.178
|
Human |
|
|
immune effector process
|
GO:0002252 |
321 |
0.178
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.174
|
Worm |
|
|
regulation of feeding behavior
|
GO:0060259 |
3 |
0.173
|
Fly |
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.172
|
Mouse Fly |
|
|
glucan metabolic process
|
GO:0044042 |
32 |
0.172
|
Mouse |
|
|
positive regulation of insulin receptor signaling pathway
|
GO:0046628 |
4 |
0.170
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.169
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.169
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.167
|
Mouse Fly |
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.166
|
|
|
|
regulation of nuclear division
|
GO:0051783 |
56 |
0.165
|
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
48 |
0.165
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.165
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.165
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.163
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.162
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.161
|
Mouse Fly |
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.158
|
Human |
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.157
|
Human |
|
|
carbohydrate transport
|
GO:0008643 |
62 |
0.157
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
56 |
0.155
|
Mouse |
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.154
|
Human |
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.153
|
Zebrafish |
|
|
response to growth factor
|
GO:0070848 |
198 |
0.151
|
Mouse |
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.151
|
Human |
|
|
memory
|
GO:0007613 |
58 |
0.149
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.149
|
Rat |
|
|
hormone secretion
|
GO:0046879 |
128 |
0.148
|
|
|
|
embryonic limb morphogenesis
|
GO:0030326 |
126 |
0.147
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
26 |
0.147
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
74 |
0.147
|
|
|
|
energy derivation by oxidation of organic compounds
|
GO:0015980 |
77 |
0.147
|
Mouse |
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.146
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
96 |
0.146
|
Zebrafish |
|
|
regulation of protein binding
|
GO:0043393 |
60 |
0.143
|
|
|
|
regulation of phospholipase c activity
|
GO:1900274 |
3 |
0.142
|
|
|
|
lipid transport
|
GO:0006869 |
98 |
0.142
|
|
|
|
t cell activation involved in immune response
|
GO:0002286 |
43 |
0.140
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.138
|
|
|
|
monosaccharide transport
|
GO:0015749 |
58 |
0.138
|
|
|
|
cell maturation
|
GO:0048469 |
127 |
0.138
|
Fly |
|
|
lung epithelial cell differentiation
|
GO:0060487 |
29 |
0.137
|
|
|
|
protein heterotetramerization
|
GO:0051290 |
4 |
0.137
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.136
|
|
|
|
formation of radial glial scaffolds
|
GO:0021943 |
4 |
0.136
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.136
|
Fly |
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.136
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.135
|
Human |
|
|
exocrine system development
|
GO:0035272 |
45 |
0.134
|
|
|
|
positive regulation of cell division
|
GO:0051781 |
31 |
0.134
|
|
|
|
cell proliferation in external granule layer
|
GO:0021924 |
10 |
0.133
|
|
|
|
aminoglycan metabolic process
|
GO:0006022 |
34 |
0.132
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.132
|
Worm |
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.132
|
Worm |
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.131
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.131
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.131
|
|
|
|
neural tube closure
|
GO:0001843 |
90 |
0.130
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.129
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.128
|
|
|
|
embryonic appendage morphogenesis
|
GO:0035113 |
126 |
0.128
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.127
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.125
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.125
|
Mouse Fly |
|
|
circulatory system process
|
GO:0003013 |
197 |
0.124
|
|
|
|
negative regulation of translation
|
GO:0017148 |
22 |
0.123
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.123
|
Fly |
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.122
|
|
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
60 |
0.122
|
|
|
|
regulation of fat cell differentiation
|
GO:0045598 |
81 |
0.120
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.119
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.119
|
Mouse Fly |
|
|
positive regulation of transcription elongation from rna polymerase ii promoter
|
GO:0032968 |
2 |
0.118
|
|
|
|
hexose transport
|
GO:0008645 |
56 |
0.118
|
|
|
|
female sex differentiation
|
GO:0046660 |
84 |
0.117
|
Fly |
|
|
endocytosis
|
GO:0006897 |
168 |
0.117
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.117
|
|
|
|
lipid catabolic process
|
GO:0016042 |
69 |
0.116
|
|
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
40 |
0.115
|
Rat |
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.115
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.115
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.114
|
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.114
|
Worm |
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.113
|
Fly |
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.113
|
|
|
|
regulation of cell projection assembly
|
GO:0060491 |
38 |
0.110
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.109
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.108
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.106
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.106
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
40 |
0.106
|
|
|
|
regulation of cell size
|
GO:0008361 |
72 |
0.106
|
Fly |
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.105
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.105
|
|
|
|
positive regulation of interleukin 5 secretion
|
GO:2000664 |
1 |
0.104
|
|
|
|
photoreceptor cell development
|
GO:0042461 |
40 |
0.104
|
|
|
|
regulation of glucose transport
|
GO:0010827 |
32 |
0.104
|
|
|
|
hindbrain development
|
GO:0030902 |
128 |
0.104
|
|
|
|
regulation of mitochondrion organization
|
GO:0010821 |
27 |
0.103
|
|
|
|
clara cell differentiation
|
GO:0060486 |
4 |
0.103
|
|
|
|
germline stem cell asymmetric division
|
GO:0098728 |
2 |
0.103
|
Fly |
|
|
hemostasis
|
GO:0007599 |
78 |
0.102
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.102
|
Zebrafish |
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.101
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.101
|
Rat Fly |
|
|
protein targeting
|
GO:0006605 |
143 |
0.101
|
Worm |
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.101
|
Mouse |
|
|
positive regulation of lipid biosynthetic process
|
GO:0046889 |
18 |
0.100
|
Rat |
|
|
embryonic skeletal system development
|
GO:0048706 |
120 |
0.100
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.099
|
|
|
|
regulation of glycogen biosynthetic process
|
GO:0005979 |
7 |
0.099
|
Mouse |
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.099
|
|
|
|
nuclear import
|
GO:0051170 |
95 |
0.099
|
Worm |
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.098
|
|
|
|
negative regulation of cellular response to growth factor stimulus
|
GO:0090288 |
46 |
0.097
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.097
|
|
|
|
positive regulation of phospholipase activity
|
GO:0010518 |
3 |
0.097
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.096
|
Human |
|
|
prostate gland development
|
GO:0030850 |
48 |
0.096
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.096
|
Human |
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.096
|
|
|
|
axon ensheathment
|
GO:0008366 |
76 |
0.095
|
|
|
|
apical constriction
|
GO:0003383 |
4 |
0.095
|
|
|
|
neural tube formation
|
GO:0001841 |
108 |
0.095
|
|
|
|
ear development
|
GO:0043583 |
200 |
0.094
|
Zebrafish |
|
|
epithelial cell migration
|
GO:0010631 |
63 |
0.093
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
71 |
0.093
|
Zebrafish |
|
|
neural tube development
|
GO:0021915 |
160 |
0.093
|
|
|
|
defecation
|
GO:0030421 |
1 |
0.093
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.092
|
|
|
|
negative regulation of synapse assembly
|
GO:0051964 |
3 |
0.092
|
|
|
|
positive regulation of phospholipase c activity
|
GO:0010863 |
2 |
0.092
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
61 |
0.091
|
Worm |
|
|
forebrain generation of neurons
|
GO:0021872 |
63 |
0.090
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.090
|
|
|
|
cell proliferation in hindbrain
|
GO:0021534 |
10 |
0.090
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.090
|
Mouse Fly |
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.089
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.089
|
Human |
|
|
multi organism reproductive behavior
|
GO:0044705 |
29 |
0.089
|
Fly |
|
|
ensheathment of neurons
|
GO:0007272 |
76 |
0.089
|
|
|
|
schwann cell development
|
GO:0014044 |
22 |
0.088
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
88 |
0.088
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
52 |
0.087
|
Worm |
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.087
|
|
|
|
retina morphogenesis in camera type eye
|
GO:0060042 |
45 |
0.087
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.086
|
Rat |
|
|
neuron maturation
|
GO:0042551 |
29 |
0.086
|
Fly |
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.086
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.086
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.086
|
|
|
|
positive regulation of cell growth
|
GO:0030307 |
33 |
0.085
|
Fly |
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.084
|
|
|
|
regulation of polysaccharide biosynthetic process
|
GO:0032885 |
7 |
0.084
|
Mouse |
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.084
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
74 |
0.084
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.083
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.083
|
|
|
|
syncytium formation
|
GO:0006949 |
43 |
0.083
|
Fly |
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.083
|
Mouse |
|
|
molting cycle
|
GO:0042303 |
90 |
0.082
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.082
|
Worm |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.082
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.082
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.081
|
|
|
|
prostate gland morphogenesis
|
GO:0060512 |
32 |
0.081
|
|
|
|
nuclear transcribed mrna catabolic process deadenylation dependent decay
|
GO:0000288 |
12 |
0.081
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.081
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.080
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
64 |
0.080
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
74 |
0.080
|
Zebrafish |
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.080
|
|
|
|
response to pain
|
GO:0048265 |
26 |
0.080
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.079
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.078
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.078
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.078
|
|
|
|
negative regulation of planar cell polarity pathway involved in pericardium morphogenesis
|
GO:2000166 |
1 |
0.077
|
|
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
41 |
0.077
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.077
|
|
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.077
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
93 |
0.077
|
|
|
|
plasma membrane long chain fatty acid transport
|
GO:0015911 |
1 |
0.076
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.076
|
Human |
|
|
negative regulation of mapk cascade
|
GO:0043409 |
65 |
0.076
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.076
|
|
|
|
regulation of cellular response to insulin stimulus
|
GO:1900076 |
30 |
0.076
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.075
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
48 |
0.075
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.075
|
Mouse Fly |
|
|
filopodium assembly
|
GO:0046847 |
19 |
0.075
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.074
|
Human Zebrafish |
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.074
|
Rat |
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.074
|
Human |
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.073
|
Mouse |
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.073
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
59 |
0.073
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.072
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.072
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.072
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.072
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.072
|
|
|
|
negative regulation of endothelial cell migration
|
GO:0010596 |
4 |
0.071
|
|
|
|
anion transport
|
GO:0006820 |
177 |
0.071
|
Mouse |
|
|
sulfur compound biosynthetic process
|
GO:0044272 |
37 |
0.071
|
|
|
|
neuron migration
|
GO:0001764 |
122 |
0.071
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.071
|
Human Rat |
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.071
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
61 |
0.071
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.071
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.071
|
|
|
|
primary neural tube formation
|
GO:0014020 |
95 |
0.070
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.069
|
Worm |
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.069
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.068
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.068
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.068
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.068
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
149 |
0.067
|
|
|
|
hair cycle
|
GO:0042633 |
90 |
0.067
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.067
|
Mouse |
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.067
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.067
|
Worm |
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.066
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.065
|
|
|
|
regulation of melanocyte differentiation
|
GO:0045634 |
7 |
0.065
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.065
|
|
|
|
lung alveolus development
|
GO:0048286 |
45 |
0.065
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.064
|
Worm |
|
|
response to alcohol
|
GO:0097305 |
48 |
0.063
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.063
|
|
|
|
negative regulation of mitochondrion organization
|
GO:0010823 |
9 |
0.063
|
|
|
|
central nervous system neuron development
|
GO:0021954 |
67 |
0.063
|
|
|
|
positive regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903052 |
31 |
0.063
|
|
|
|
fatty acid transmembrane transport
|
GO:1902001 |
1 |
0.063
|
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.063
|
|
|
|
muscle adaptation
|
GO:0043500 |
39 |
0.063
|
|
|
|
fibroblast proliferation
|
GO:0048144 |
35 |
0.062
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.062
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.062
|
|
|
|
regulation of glucose import
|
GO:0046324 |
26 |
0.061
|
|
|
|
methylation
|
GO:0032259 |
134 |
0.061
|
|
|
|
neuroblast differentiation
|
GO:0014016 |
2 |
0.061
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.061
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.061
|
Worm |
|
|
retinal cone cell development
|
GO:0046549 |
8 |
0.061
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.060
|
|
|
|
somitogenesis
|
GO:0001756 |
69 |
0.060
|
|
|
|
hindlimb morphogenesis
|
GO:0035137 |
42 |
0.060
|
|
|
|
prostate glandular acinus morphogenesis
|
GO:0060526 |
7 |
0.060
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.060
|
Zebrafish |
|
|
peptide secretion
|
GO:0002790 |
114 |
0.060
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.060
|
|
|
|
mammary gland epithelium development
|
GO:0061180 |
65 |
0.060
|
|
|
|
axis elongation involved in somitogenesis
|
GO:0090245 |
4 |
0.060
|
|
|
|
central nervous system projection neuron axonogenesis
|
GO:0021952 |
21 |
0.059
|
|
|
|
neuron projection regeneration
|
GO:0031102 |
14 |
0.059
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.059
|
|
|
|
cardiac right atrium morphogenesis
|
GO:0003213 |
3 |
0.059
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
234 |
0.059
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.059
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.058
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
56 |
0.058
|
|
|
|
regulation of filopodium assembly
|
GO:0051489 |
13 |
0.058
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.057
|
|
|
|
lung lobe morphogenesis
|
GO:0060463 |
9 |
0.057
|
|
|
|
glial cell development
|
GO:0021782 |
54 |
0.057
|
|
|
|
positive regulation of dna templated transcription elongation
|
GO:0032786 |
2 |
0.057
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.057
|
|
|
|
lipid storage
|
GO:0019915 |
36 |
0.056
|
Worm |
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.056
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.056
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
79 |
0.056
|
Zebrafish |
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.056
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
85 |
0.056
|
|
|
|
interleukin 5 secretion
|
GO:0072603 |
2 |
0.055
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.055
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.055
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.055
|
Human |
|
|
adult locomotory behavior
|
GO:0008344 |
91 |
0.055
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
93 |
0.055
|
|
|
|
pancreas development
|
GO:0031016 |
57 |
0.055
|
|
|
|
appendage development
|
GO:0048736 |
166 |
0.054
|
|
|
|
ribonucleoprotein complex subunit organization
|
GO:0071826 |
28 |
0.054
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.054
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.054
|
Zebrafish |
|
|
dna methylation
|
GO:0006306 |
43 |
0.054
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.053
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.053
|
Human |
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.053
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.053
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.053
|
|
|
|
protein alkylation
|
GO:0008213 |
81 |
0.053
|
|
|
|
regulation of mesenchymal cell proliferation involved in lung development
|
GO:2000790 |
2 |
0.053
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
51 |
0.053
|
|
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.052
|
Worm Fly |
|
|
proteoglycan metabolic process
|
GO:0006029 |
38 |
0.052
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.052
|
Zebrafish |
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.052
|
Worm |
|
|
regulation of cerebellar granule cell precursor proliferation
|
GO:0021936 |
12 |
0.052
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.052
|
|
|
|
organelle fission
|
GO:0048285 |
170 |
0.052
|
|
|
|
olfactory learning
|
GO:0008355 |
2 |
0.051
|
|
|
|
g protein coupled acetylcholine receptor signaling pathway
|
GO:0007213 |
4 |
0.051
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
88 |
0.051
|
|
|
|
forebrain neuron differentiation
|
GO:0021879 |
52 |
0.051
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
88 |
0.051
|
|
|
|
regulation of cell shape
|
GO:0008360 |
39 |
0.051
|
|
|
|
cerebellum morphogenesis
|
GO:0021587 |
42 |
0.051
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.051
|
|
|
|
cell differentiation in hindbrain
|
GO:0021533 |
24 |
0.051
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.051
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.051
|
|
|
|
reproductive behavior
|
GO:0019098 |
32 |
0.050
|
Fly |
|
|
activation of adenylate cyclase activity
|
GO:0007190 |
4 |
0.050
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.050
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.050
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
207 |
0.050
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.050
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
82 |
0.050
|
|
|
|
protein import
|
GO:0017038 |
101 |
0.050
|
Worm |
|
|
regulation of peptide hormone secretion
|
GO:0090276 |
75 |
0.050
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
61 |
0.049
|
|
|
|
positive regulation of steroid biosynthetic process
|
GO:0010893 |
4 |
0.049
|
Rat |
|
|
positive regulation of interleukin 13 secretion
|
GO:2000667 |
1 |
0.049
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
60 |
0.049
|
|
|
|
substrate dependent cerebral cortex tangential migration
|
GO:0021825 |
3 |
0.049
|
|
|
|
peptide hormone secretion
|
GO:0030072 |
109 |
0.049
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
85 |
0.049
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.049
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.048
|
|
|
|
regulation of steroid metabolic process
|
GO:0019218 |
39 |
0.048
|
Rat |
|
|
microtubule based process
|
GO:0007017 |
236 |
0.048
|
|
|
|
sensory system development
|
GO:0048880 |
3 |
0.048
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.048
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.048
|
Fly |
|
|
muscle system process
|
GO:0003012 |
141 |
0.048
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.048
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.048
|
|
