Mus musculus

120 known processes

Igfbp5

insulin-like growth factor binding protein 5

(Aliases: IGFBP-5,AW208790,IGFBP-5P,AI256729)

Igfbp5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
skeletal system development GO:0001501 356 0.688
cartilage development GO:0051216 140 0.682
kidney development GO:0001822 213 0.526
urogenital system development GO:0001655 261 0.410
bone development GO:0060348 120 0.404
neuron projection guidance GO:0097485 141 0.379
ossification GO:0001503 216 0.335
negative regulation of ossification GO:0030279 49 0.293
appendage development GO:0048736 166 0.264
negative regulation of cell proliferation GO:0008285 296 0.262
Human
skeletal muscle organ development GO:0060538 163 0.261
Rat
response to growth factor GO:0070848 198 0.254
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.251
connective tissue development GO:0061448 179 0.245
extracellular matrix organization GO:0030198 147 0.227
muscle tissue development GO:0060537 308 0.213
Rat
cellular response to growth factor stimulus GO:0071363 197 0.210
glial cell differentiation GO:0010001 131 0.198
chondrocyte differentiation GO:0002062 72 0.192
negative regulation of cell development GO:0010721 169 0.191
regulation of epithelial cell proliferation GO:0050678 141 0.189
renal system development GO:0072001 225 0.168
forebrain development GO:0030900 302 0.163
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.163
respiratory tube development GO:0030323 167 0.158
extracellular structure organization GO:0043062 148 0.152
axon guidance GO:0007411 141 0.146
skeletal system morphogenesis GO:0048705 203 0.145
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.134
establishment of protein localization to organelle GO:0072594 118 0.131
heart morphogenesis GO:0003007 178 0.129
positive regulation of nervous system development GO:0051962 221 0.128
regulation of cellular amine metabolic process GO:0033238 20 0.119
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.118
embryonic skeletal system development GO:0048706 120 0.118
morphogenesis of a branching structure GO:0001763 203 0.117
digestive tract morphogenesis GO:0048546 147 0.116
regulation of membrane potential GO:0042391 192 0.113
single organism nuclear import GO:1902593 95 0.106
respiratory system development GO:0060541 190 0.106
wnt signaling pathway GO:0016055 188 0.105
chemotaxis GO:0006935 247 0.105
axonogenesis GO:0007409 274 0.103
protein import GO:0017038 101 0.101
digestive system development GO:0055123 200 0.099
blood vessel morphogenesis GO:0048514 285 0.099
epithelial tube morphogenesis GO:0060562 303 0.098
gland development GO:0048732 330 0.097
retina development in camera type eye GO:0060041 119 0.096
digestive tract development GO:0048565 190 0.095
positive regulation of cell development GO:0010720 237 0.094
intracellular protein transport GO:0006886 204 0.094
stem cell differentiation GO:0048863 268 0.093
negative regulation of immune system process GO:0002683 209 0.093
camera type eye development GO:0043010 266 0.091
stem cell proliferation GO:0072089 117 0.090
response to transforming growth factor beta GO:0071559 88 0.089
blood circulation GO:0008015 195 0.089
regulation of neuron differentiation GO:0045664 281 0.088
regulation of system process GO:0044057 200 0.088
mitotic cell cycle GO:0000278 195 0.088
bmp signaling pathway GO:0030509 93 0.088
cytoplasmic transport GO:0016482 234 0.087
regulation of organ morphogenesis GO:2000027 144 0.086
extrinsic apoptotic signaling pathway GO:0097191 126 0.085
regulation of protein import into nucleus GO:0042306 52 0.085
regulation of apoptotic signaling pathway GO:2001233 197 0.085
cellular amine metabolic process GO:0044106 44 0.084
neural precursor cell proliferation GO:0061351 121 0.082
regulation of protein targeting GO:1903533 61 0.082
gliogenesis GO:0042063 141 0.080
limb development GO:0060173 166 0.080
striated muscle tissue development GO:0014706 293 0.079
Rat
developmental maturation GO:0021700 193 0.079
nuclear import GO:0051170 95 0.076
regulation of ossification GO:0030278 112 0.074
angiogenesis GO:0001525 201 0.073
myeloid cell differentiation GO:0030099 233 0.073
regulation of cellular amino acid metabolic process GO:0006521 5 0.072
negative regulation of mesenchymal cell proliferation GO:0072201 3 0.072
protein targeting GO:0006605 143 0.071
protein localization to organelle GO:0033365 185 0.071
limb morphogenesis GO:0035108 149 0.070
palate development GO:0060021 76 0.070
protein import into nucleus GO:0006606 95 0.070
negative regulation of epithelial cell proliferation GO:0050680 64 0.070
regulation of cytoplasmic transport GO:1903649 112 0.069
branching morphogenesis of an epithelial tube GO:0048754 159 0.069
morphogenesis of a branching epithelium GO:0061138 193 0.069
regulation of angiogenesis GO:0045765 81 0.068
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.068
formation of primary germ layer GO:0001704 77 0.067
cellular ketone metabolic process GO:0042180 84 0.067
nuclear transport GO:0051169 139 0.067
regulation of cell adhesion GO:0030155 154 0.066
regulation of protein localization GO:0032880 231 0.066
regulation of intracellular protein transport GO:0033157 82 0.065
peptidyl amino acid modification GO:0018193 336 0.065
glial cell development GO:0021782 54 0.065
skeletal muscle cell differentiation GO:0035914 66 0.064
smoothened signaling pathway GO:0007224 105 0.064
action potential GO:0001508 78 0.063
regulation of protein localization to nucleus GO:1900180 60 0.062
embryonic skeletal system morphogenesis GO:0048704 91 0.062
negative regulation of molecular function GO:0044092 258 0.062
regulation of cell cycle process GO:0010564 160 0.062
protein maturation GO:0051604 176 0.061
multicellular organismal signaling GO:0035637 91 0.060
regulation of cellular response to growth factor stimulus GO:0090287 82 0.060
amine metabolic process GO:0009308 45 0.060
embryonic appendage morphogenesis GO:0035113 126 0.059
apoptotic signaling pathway GO:0097190 306 0.059
negative regulation of glial cell proliferation GO:0060253 4 0.058
regulation of osteoblast differentiation GO:0045667 67 0.058
pallium development GO:0021543 120 0.058
neuronal action potential GO:0019228 54 0.057
nucleocytoplasmic transport GO:0006913 139 0.057
epithelial cell proliferation GO:0050673 174 0.057
cell fate commitment GO:0045165 210 0.056
prostate gland morphogenesis GO:0060512 32 0.055
regulation of wnt signaling pathway GO:0030111 123 0.055
stem cell development GO:0048864 219 0.055
muscle cell differentiation GO:0042692 261 0.054
kidney epithelium development GO:0072073 121 0.054
inorganic ion transmembrane transport GO:0098660 234 0.054
embryonic organ morphogenesis GO:0048562 276 0.053
protein localization to nucleus GO:0034504 121 0.052
sulfur compound metabolic process GO:0006790 100 0.052
regulation of muscle tissue development GO:1901861 97 0.052
positive regulation of cellular amine metabolic process GO:0033240 5 0.051
central nervous system neuron differentiation GO:0021953 162 0.050
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.050
regulation of cell projection organization GO:0031344 206 0.050
cell adhesion GO:0007155 329 0.049
mitotic cell cycle process GO:1903047 159 0.049
cellular amino acid metabolic process GO:0006520 103 0.048
calcium ion transmembrane transport GO:0070588 85 0.048
gonad development GO:0008406 141 0.047
positive regulation of nucleocytoplasmic transport GO:0046824 30 0.047
sensory organ morphogenesis GO:0090596 242 0.047
cellular lipid metabolic process GO:0044255 323 0.047
regulation of cell cycle GO:0051726 281 0.046
formation of organ boundary GO:0010160 1 0.046
negative regulation of leukocyte differentiation GO:1902106 51 0.045
multicellular organism growth GO:0035264 161 0.044
actin cytoskeleton organization GO:0030036 220 0.044
regulation of nucleocytoplasmic transport GO:0046822 73 0.044
homeostasis of number of cells GO:0048872 210 0.044
compound eye development GO:0048749 1 0.043
regulation of striated muscle cell differentiation GO:0051153 81 0.043
cardiac chamber development GO:0003205 108 0.043
cell division GO:0051301 120 0.042
regionalization GO:0003002 337 0.042
protein oligomerization GO:0051259 67 0.041
myotube differentiation GO:0014902 105 0.041
cerebellum development GO:0021549 77 0.041
canonical wnt signaling pathway GO:0060070 130 0.041
regulation of bmp signaling pathway GO:0030510 60 0.040
nephron development GO:0072006 109 0.040
circulatory system process GO:0003013 197 0.040
regulation of cellular ketone metabolic process GO:0010565 66 0.039
cardiac muscle tissue development GO:0048738 130 0.039
regulation of reproductive process GO:2000241 66 0.039
negative regulation of bmp signaling pathway GO:0030514 35 0.039
transmission of nerve impulse GO:0019226 76 0.038
positive regulation of cell death GO:0010942 224 0.037
muscle cell development GO:0055001 133 0.037
prostate gland development GO:0030850 48 0.037
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.037
tube formation GO:0035148 140 0.037
cardiac chamber morphogenesis GO:0003206 93 0.037
negative regulation of cellular response to growth factor stimulus GO:0090288 46 0.037
astrocyte differentiation GO:0048708 43 0.037
mesonephric epithelium development GO:0072163 94 0.037
stem cell maintenance GO:0019827 130 0.036
negative regulation of neuron differentiation GO:0045665 101 0.036
regulation of actin filament based process GO:0032970 99 0.036
muscle cell proliferation GO:0033002 52 0.035
Human
response to organonitrogen compound GO:0010243 246 0.035
Human
ensheathment of neurons GO:0007272 76 0.035
telencephalon development GO:0021537 186 0.035
single organismal cell cell adhesion GO:0016337 131 0.035
metanephros development GO:0001656 79 0.035
germ cell development GO:0007281 185 0.034
striated muscle cell development GO:0055002 125 0.034
positive regulation of apoptotic process GO:0043065 217 0.034
hindbrain development GO:0030902 128 0.033
regulation of epithelial to mesenchymal transition GO:0010717 22 0.033
neural tube formation GO:0001841 108 0.033
odontogenesis GO:0042476 78 0.033
positive regulation of programmed cell death GO:0043068 218 0.033
bone morphogenesis GO:0060349 78 0.033
primary neural tube formation GO:0014020 95 0.033
muscle fiber development GO:0048747 76 0.033
mesonephric duct morphogenesis GO:0072180 4 0.032
lung morphogenesis GO:0060425 50 0.032
regulation of stem cell differentiation GO:2000736 50 0.032
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.031
lung development GO:0030324 164 0.031
nitrogen compound transport GO:0071705 271 0.031
circadian rhythm GO:0007623 114 0.031
regulation of proteolysis GO:0030162 164 0.031
prostate gland epithelium morphogenesis GO:0060740 31 0.031
cell growth GO:0016049 130 0.031
small gtpase mediated signal transduction GO:0007264 97 0.030
trabecula morphogenesis GO:0061383 40 0.030
leukocyte differentiation GO:0002521 342 0.030
negative regulation of cell cycle GO:0045786 123 0.030
axon ensheathment GO:0008366 76 0.030
neural tube development GO:0021915 160 0.030
regulation of organelle organization GO:0033043 289 0.029
muscle system process GO:0003012 141 0.029
negative regulation of apoptotic signaling pathway GO:2001234 104 0.029
negative regulation of cellular component organization GO:0051129 194 0.029
myelination GO:0042552 74 0.029
regulation of cell migration GO:0030334 219 0.029
Human
single organism cell adhesion GO:0098602 156 0.029
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.029
appendage morphogenesis GO:0035107 149 0.029
skeletal muscle fiber development GO:0048741 58 0.028
negative regulation of protein metabolic process GO:0051248 282 0.028
Human
organ growth GO:0035265 117 0.028
regulation of wnt signaling pathway planar cell polarity pathway GO:2000095 10 0.028
regulation of cell substrate adhesion GO:0010810 73 0.028
carbohydrate homeostasis GO:0033500 128 0.028
ameboidal type cell migration GO:0001667 128 0.027
regulation of secretion GO:0051046 274 0.027
positive regulation of intracellular protein transport GO:0090316 42 0.027
cell type specific apoptotic process GO:0097285 268 0.027
determination of left right symmetry GO:0007368 80 0.027
myotube cell development GO:0014904 60 0.027
polarity specification of proximal distal axis GO:0010085 2 0.027
ribonucleotide metabolic process GO:0009259 291 0.027
myeloid leukocyte differentiation GO:0002573 119 0.027
regulation of homeostatic process GO:0032844 182 0.027
inorganic cation transmembrane transport GO:0098662 207 0.027
retinal blood vessel morphogenesis GO:0061304 3 0.027
positive regulation of protein modification process GO:0031401 299 0.027
regulation of hormone levels GO:0010817 211 0.026
cerebral cortex development GO:0021987 86 0.026
mapk cascade GO:0000165 281 0.026
Mouse
regulation of anatomical structure size GO:0090066 178 0.026
morphogenesis of embryonic epithelium GO:0016331 159 0.026
lymphocyte differentiation GO:0030098 242 0.026
organelle fission GO:0048285 170 0.026
pigmentation GO:0043473 71 0.025
embryonic limb morphogenesis GO:0030326 126 0.025
cell substrate adhesion GO:0031589 130 0.025
mitotic cytokinesis GO:0000281 4 0.025
negative regulation of hydrolase activity GO:0051346 71 0.025
peripheral nervous system development GO:0007422 53 0.025
nucleoside phosphate metabolic process GO:0006753 338 0.025
lateral inhibition GO:0046331 1 0.025
skin development GO:0043588 220 0.025
regulation of mesenchymal cell proliferation involved in lung development GO:2000790 2 0.025
principal sensory nucleus of trigeminal nerve development GO:0021740 2 0.024
ear development GO:0043583 200 0.024
fat cell differentiation GO:0045444 160 0.024
mesoderm development GO:0007498 100 0.024
regulation of body fluid levels GO:0050878 162 0.024
regulation of leukocyte differentiation GO:1902105 159 0.024
regulation of kinase activity GO:0043549 249 0.024
regulation of myotube differentiation GO:0010830 62 0.024
multi multicellular organism process GO:0044706 109 0.023
central nervous system projection neuron axonogenesis GO:0021952 21 0.023
positive regulation of protein localization to nucleus GO:1900182 30 0.023
mesonephric tubule morphogenesis GO:0072171 63 0.023
sensory perception GO:0007600 245 0.023
myoblast differentiation GO:0045445 52 0.023
endothelial cell migration GO:0043542 44 0.023
cardiac ventricle development GO:0003231 83 0.023
cardiac muscle tissue growth GO:0055017 37 0.023
oligodendrocyte differentiation GO:0048709 53 0.023
regulation of planar cell polarity pathway involved in axis elongation GO:2000040 3 0.023
regulation of actin cytoskeleton organization GO:0032956 84 0.023
metencephalon development GO:0022037 89 0.023
regulation of cartilage development GO:0061035 44 0.023
cellular carbohydrate metabolic process GO:0044262 119 0.023
regulation of mapk cascade GO:0043408 248 0.023
Mouse
cerebellum vasculature morphogenesis GO:0061301 1 0.023
clara cell differentiation GO:0060486 4 0.023
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.023
gastrulation GO:0007369 116 0.022
nephron morphogenesis GO:0072028 69 0.022
cellular component assembly involved in morphogenesis GO:0010927 139 0.022
cellular response to hormone stimulus GO:0032870 150 0.022
regulation of protein transport GO:0051223 163 0.022
positive regulation of cell cycle GO:0045787 92 0.022
regulation of myeloid cell differentiation GO:0045637 96 0.022
positive regulation of ossification GO:0045778 47 0.022
positive regulation of cell projection organization GO:0031346 95 0.022
rhythmic process GO:0048511 174 0.021
regulation of astrocyte differentiation GO:0048710 20 0.021
regulation of chondrocyte differentiation GO:0032330 33 0.021
positive regulation of intracellular transport GO:0032388 70 0.021
central nervous system neuron axonogenesis GO:0021955 28 0.021
epithelial cell migration GO:0010631 63 0.021
glucose homeostasis GO:0042593 128 0.021
negative regulation of photoreceptor cell differentiation GO:0046533 4 0.021
syncytium formation by plasma membrane fusion GO:0000768 42 0.021
hindlimb morphogenesis GO:0035137 42 0.021
positive regulation of bmp signaling pathway GO:0030513 23 0.021
inter male aggressive behavior GO:0002121 3 0.021
posttranscriptional regulation of gene expression GO:0010608 155 0.021
Human
nucleoside phosphate catabolic process GO:1901292 222 0.021
actin filament polymerization GO:0030041 44 0.021
negative regulation of nervous system development GO:0051961 156 0.021
cellular response to organonitrogen compound GO:0071417 145 0.020
Human
cardiac ventricle morphogenesis GO:0003208 50 0.020
regulation of lymphocyte activation GO:0051249 240 0.020
rho protein signal transduction GO:0007266 32 0.020
regulation of intracellular transport GO:0032386 159 0.020
somatic stem cell maintenance GO:0035019 47 0.020
plasma membrane organization GO:0007009 90 0.020
neural retina development GO:0003407 41 0.020
striated muscle cell proliferation GO:0014855 39 0.020
lateral line system development GO:0048925 1 0.020
regulation of mitotic cell cycle GO:0007346 126 0.020
epithelium migration GO:0090132 63 0.020
response to extracellular stimulus GO:0009991 127 0.020
mesonephric tubule development GO:0072164 94 0.020
proteoglycan metabolic process GO:0006029 38 0.020
regulation of multi organism process GO:0043900 111 0.020
epithelial cell development GO:0002064 159 0.020
mammary gland epithelium development GO:0061180 65 0.020
osteoclast differentiation GO:0030316 62 0.019
positive regulation of cell adhesion GO:0045785 80 0.019
protein catabolic process GO:0030163 221 0.019
mesonephros development GO:0001823 97 0.019
positive regulation of wnt signaling pathway planar cell polarity pathway GO:2000096 5 0.019
regulation of cell cycle phase transition GO:1901987 77 0.019
negative regulation of cellular protein metabolic process GO:0032269 247 0.019
Human
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.019
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 26 0.019
positive regulation of cytoplasmic transport GO:1903651 40 0.019
endochondral bone morphogenesis GO:0060350 50 0.019
heart trabecula morphogenesis GO:0061384 26 0.019
cerebellum morphogenesis GO:0021587 42 0.019
carbohydrate derivative biosynthetic process GO:1901137 183 0.019
oligodendrocyte development GO:0014003 20 0.019
heart trabecula formation GO:0060347 14 0.019
dendrite development GO:0016358 115 0.019
synapse organization GO:0050808 125 0.019
regulation of feeding behavior GO:0060259 3 0.019
membrane organization GO:0061024 245 0.018
locomotory behavior GO:0007626 195 0.018
negative regulation of cell adhesion GO:0007162 45 0.018
regulation of gliogenesis GO:0014013 50 0.018
cytokine production GO:0001816 319 0.018
positive regulation of cell substrate adhesion GO:0010811 47 0.018
defense response to other organism GO:0098542 197 0.018
divalent metal ion transport GO:0070838 172 0.018
mesenchyme development GO:0060485 152 0.018
epiblast cell extraembryonic ectoderm cell signaling involved in anterior posterior axis specification GO:0060802 1 0.018
muscle contraction GO:0006936 101 0.018
positive regulation of growth GO:0045927 104 0.018
protein processing GO:0016485 163 0.018
response to acid chemical GO:0001101 111 0.018
organonitrogen compound biosynthetic process GO:1901566 192 0.018
endocardial cell differentiation GO:0060956 4 0.018
trigeminal sensory nucleus development GO:0021730 2 0.018
kidney morphogenesis GO:0060993 83 0.018
sequestering of calcium ion GO:0051208 18 0.017
cognition GO:0050890 149 0.017
covalent chromatin modification GO:0016569 163 0.017
response to radiation GO:0009314 165 0.017
cation transmembrane transport GO:0098655 266 0.017
adult behavior GO:0030534 135 0.017
regulation of epithelial cell migration GO:0010632 35 0.017
macromolecule catabolic process GO:0009057 281 0.017
cell cell signaling involved in cell fate commitment GO:0045168 35 0.017
exocrine system development GO:0035272 45 0.017
spermatogenesis GO:0007283 284 0.017
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.017
wound healing GO:0042060 157 0.017
nephron epithelium development GO:0072009 92 0.017
regulation of hydrolase activity GO:0051336 246 0.017
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.017
cell cycle g1 s phase transition GO:0044843 57 0.017
regulation of neuron projection development GO:0010975 169 0.017
heart contraction GO:0060047 93 0.017
peptide hormone secretion GO:0030072 109 0.017
peptide secretion GO:0002790 114 0.017
epithelial cell differentiation involved in mammary gland alveolus development GO:0061030 4 0.017
negative regulation of osteoclast differentiation GO:0045671 12 0.017
regulation of myeloid leukocyte differentiation GO:0002761 58 0.017
inner ear morphogenesis GO:0042472 101 0.017
extracellular matrix assembly GO:0085029 12 0.017
regulation of smoothened signaling pathway GO:0008589 58 0.017
mesoderm morphogenesis GO:0048332 64 0.017
pharynx development GO:0060465 1 0.017
midgut development GO:0007494 4 0.016
asymmetric stem cell division GO:0098722 3 0.016
ras protein signal transduction GO:0007265 77 0.016
regulation of lymphocyte differentiation GO:0045619 107 0.016
ear morphogenesis GO:0042471 118 0.016
axial mesoderm formation GO:0048320 3 0.016
glycoprotein metabolic process GO:0009100 116 0.016
spermatid development GO:0007286 108 0.016
positive regulation of epithelial to mesenchymal transition GO:0010718 13 0.016
oxidation reduction process GO:0055114 342 0.016
muscle tissue morphogenesis GO:0060415 53 0.016
regulation of catenin import into nucleus GO:0035412 5 0.016
branching involved in ureteric bud morphogenesis GO:0001658 56 0.016
somite development GO:0061053 81 0.016
floor plate morphogenesis GO:0033505 3 0.016
developmental programmed cell death GO:0010623 41 0.016
purine ribonucleoside catabolic process GO:0046130 205 0.016
regulation of receptor activity GO:0010469 41 0.016
immune effector process GO:0002252 321 0.016
ribose phosphate metabolic process GO:0019693 291 0.016
positive regulation of cell cycle process GO:0090068 61 0.016
regulation of transporter activity GO:0032409 57 0.015
apical constriction GO:0003383 4 0.015
b cell activation GO:0042113 161 0.015
tendon cell differentiation GO:0035990 4 0.015
spinal cord development GO:0021510 81 0.015
cyclic nucleotide metabolic process GO:0009187 59 0.015
cellular transition metal ion homeostasis GO:0046916 32 0.015
protein modification by small protein conjugation GO:0032446 187 0.015
growth involved in heart morphogenesis GO:0003241 4 0.015
negative regulation of cell fate specification GO:0009996 4 0.015
regulation of establishment of planar polarity GO:0090175 28 0.015
regeneration GO:0031099 38 0.015
organelle assembly GO:0070925 177 0.015
planar cell polarity pathway involved in axis elongation GO:0003402 4 0.015
ureteric bud development GO:0001657 94 0.015
positive regulation of epithelial cell proliferation GO:0050679 68 0.015
mesendoderm development GO:0048382 3 0.015
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.015
positive regulation of protein phosphorylation GO:0001934 242 0.015
regulation of circadian rhythm GO:0042752 58 0.015
negative regulation of lymphocyte activation GO:0051250 91 0.015
cellular response to acid chemical GO:0071229 68 0.015
notch signaling pathway GO:0007219 71 0.014
epithelial cell morphogenesis GO:0003382 41 0.014
sprouting angiogenesis GO:0002040 26 0.014
regulation of organ formation GO:0003156 34 0.014
aminoglycan metabolic process GO:0006022 34 0.014
negative regulation of growth GO:0045926 99 0.014
axis elongation GO:0003401 30 0.014
chondroitin sulfate proteoglycan metabolic process GO:0050654 20 0.014
transition metal ion homeostasis GO:0055076 54 0.014
histone modification GO:0016570 159 0.014
lung alveolus development GO:0048286 45 0.014
mesenchymal cell apoptotic process involved in nephron morphogenesis GO:1901145 4 0.014
developmental pigmentation GO:0048066 40 0.014
blastocyst development GO:0001824 80 0.014
regulation of protein kinase activity GO:0045859 232 0.014
endoderm development GO:0007492 45 0.014
skin morphogenesis GO:0043589 38 0.014
regulation of protein processing GO:0070613 96 0.014
t cell differentiation GO:0030217 174 0.014
regulation of transferase activity GO:0051338 263 0.014
positive regulation of transferase activity GO:0051347 167 0.014
mesoderm formation GO:0001707 62 0.014
wnt signaling pathway planar cell polarity pathway GO:0060071 27 0.014
positive regulation of neuron differentiation GO:0045666 141 0.014
odontogenesis of dentin containing tooth GO:0042475 66 0.014
axis elongation involved in somitogenesis GO:0090245 4 0.014
bone remodeling GO:0046849 53 0.014
negative regulation of protein processing GO:0010955 79 0.014
regulation of vesicle mediated transport GO:0060627 139 0.013
syncytium formation GO:0006949 43 0.013
cytokine mediated signaling pathway GO:0019221 115 0.013
trabecula formation GO:0060343 24 0.013
negative regulation of osteoblast differentiation GO:0045668 30 0.013
regulation of cell activation GO:0050865 289 0.013
insulin secretion GO:0030073 89 0.013
peripheral nervous system neuron axonogenesis GO:0048936 3 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.013
negative regulation of endothelial cell apoptotic process GO:2000352 7 0.013
positive regulation of hydrolase activity GO:0051345 148 0.013
positive regulation of receptor activity GO:2000273 17 0.013
negative regulation of blood vessel morphogenesis GO:2000181 25 0.013
negative regulation of cell migration GO:0030336 59 0.013
Human
negative regulation of wnt signaling pathway GO:0030178 73 0.013
cation transport GO:0006812 399 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.013
glial cell migration GO:0008347 7 0.013
actin filament based movement GO:0030048 23 0.013
negative regulation of immune effector process GO:0002698 55 0.013
cerebellar cortex development GO:0021695 48 0.013
intrinsic apoptotic signaling pathway GO:0097193 132 0.013
response to symbiont GO:0009608 2 0.013
cellular ion homeostasis GO:0006873 165 0.013
cardioblast migration GO:0003260 1 0.013
nuclear division GO:0000280 158 0.013

Igfbp5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.111
musculoskeletal system disease DOID:17 0 0.111
muscle tissue disease DOID:66 0 0.097
myopathy DOID:423 0 0.097
muscular disease DOID:0080000 0 0.097
muscular dystrophy DOID:9884 0 0.021
nervous system disease DOID:863 0 0.021