Mus musculus

22 known processes

Igj

immunoglobulin joining chain

(Aliases: AI323815,Jch,9530090F24Rik)

Igj biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
stimulatory c type lectin receptor signaling pathway GO:0002223 2 0.518
activation of immune response GO:0002253 138 0.236
hematopoietic stem cell migration GO:0035701 1 0.141
positive regulation of immunological synapse formation GO:2000522 1 0.111
microglial cell activation involved in immune response GO:0002282 1 0.108
positive regulation of t cell receptor signaling pathway GO:0050862 4 0.106
immune response activating signal transduction GO:0002757 116 0.103
membrane organization GO:0061024 245 0.091
cellular ketone metabolic process GO:0042180 84 0.090
regulation of lymphocyte activation GO:0051249 240 0.089
second messenger mediated signaling GO:0019932 73 0.084
innate immune response activating cell surface receptor signaling pathway GO:0002220 4 0.083
positive regulation of cd8 positive alpha beta t cell extravasation GO:2000451 2 0.078
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation GO:2000526 1 0.074
helper t cell chemotaxis GO:0035704 1 0.073
cellular response to molecule of bacterial origin GO:0071219 83 0.069
leukocyte chemotaxis GO:0030595 69 0.066
inflammatory response GO:0006954 244 0.066
eosinophil activation involved in immune response GO:0002278 1 0.065
cellular amino acid metabolic process GO:0006520 103 0.064
positive regulation of cell activation GO:0050867 158 0.064
monocyte extravasation GO:0035696 2 0.063
positive regulation of t cell activation GO:0050870 101 0.060
regulation of cellular amine metabolic process GO:0033238 20 0.060
cd8 positive alpha beta t cell extravasation GO:0035697 3 0.060
detection of yeast GO:0001879 2 0.060
chemokine mediated signaling pathway GO:0070098 17 0.058
amine metabolic process GO:0009308 45 0.058
cell chemotaxis GO:0060326 81 0.057
regulation of vesicle mediated transport GO:0060627 139 0.056
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.056
cellular response to molecule of fungal origin GO:0071226 2 0.056
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.056
nucleotide metabolic process GO:0009117 332 0.055
sensory perception GO:0007600 245 0.055
cation transport GO:0006812 399 0.052
positive regulation of t cell extravasation GO:2000409 2 0.051
cellular lipid metabolic process GO:0044255 323 0.050
microglial cell activation GO:0001774 3 0.049
negative regulation of eosinophil degranulation GO:0043310 1 0.049
leukocyte mediated cytotoxicity GO:0001909 62 0.049
cellular amine metabolic process GO:0044106 44 0.048
detection of stimulus GO:0051606 84 0.047
response to molecule of fungal origin GO:0002238 4 0.047
cell surface pattern recognition receptor signaling pathway GO:0002752 2 0.046
regulation of t cell activation GO:0050863 170 0.046
positive regulation of t cell costimulation GO:2000525 2 0.046
cellular response to lipid GO:0071396 145 0.046
microglia differentiation GO:0014004 2 0.045
eosinophil activation GO:0043307 1 0.045
regulation of response to wounding GO:1903034 189 0.044
circulatory system process GO:0003013 197 0.044
organophosphate biosynthetic process GO:0090407 122 0.044
regulation of eosinophil degranulation GO:0043309 1 0.044
microglia development GO:0014005 2 0.044
thymic t cell selection GO:0045061 22 0.043
regulation of immune complex clearance by monocytes and macrophages GO:0090264 2 0.043
positive regulation of inflammatory response GO:0050729 47 0.042
ribose phosphate metabolic process GO:0019693 291 0.042
regulation of t cell costimulation GO:2000523 2 0.042
cellular homeostasis GO:0019725 240 0.041
apoptotic signaling pathway GO:0097190 306 0.041
detection of fungus GO:0016046 2 0.040
positive regulation of cellular amine metabolic process GO:0033240 5 0.040
positive regulation of alpha beta t cell activation GO:0046635 39 0.040
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.040
eosinophil mediated immunity GO:0002447 1 0.039
regulation of cellular amino acid metabolic process GO:0006521 5 0.039
blood circulation GO:0008015 195 0.039
myeloid cell differentiation GO:0030099 233 0.039
ion transmembrane transport GO:0034220 361 0.038
regulation of endocytosis GO:0030100 69 0.038
regulation of immunological synapse formation GO:2000520 2 0.037
immune effector process GO:0002252 321 0.037
t helper 17 cell chemotaxis GO:0035705 1 0.037
regulation of cellular ketone metabolic process GO:0010565 66 0.037
positive regulation of hematopoietic stem cell migration GO:2000473 1 0.036
positive regulation of defense response GO:0031349 124 0.035
divalent inorganic cation transport GO:0072511 178 0.035
regulation of monocyte extravasation GO:2000437 2 0.035
antigen receptor mediated signaling pathway GO:0050851 64 0.035
t cell extravasation GO:0072683 4 0.034
positive regulation of leukocyte differentiation GO:1902107 86 0.034
nucleobase containing small molecule metabolic process GO:0055086 352 0.033
blood vessel morphogenesis GO:0048514 285 0.033
immune complex clearance by monocytes and macrophages GO:0002436 2 0.033
innate immune response GO:0045087 157 0.032
Human
purine containing compound metabolic process GO:0072521 311 0.032
nitrogen compound transport GO:0071705 271 0.032
fatty acid metabolic process GO:0006631 121 0.032
adaptive immune response GO:0002250 155 0.032
Human
maintenance of location GO:0051235 89 0.031
lymphocyte mediated immunity GO:0002449 139 0.031
tissue remodeling GO:0048771 102 0.031
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.031
regulation of t cell extravasation GO:2000407 3 0.031
cell recognition GO:0008037 83 0.030
positive regulation of monocyte extravasation GO:2000439 1 0.030
aromatic compound catabolic process GO:0019439 286 0.030
calcium mediated signaling GO:0019722 46 0.029
neuron migration GO:0001764 122 0.029
regulation of cell activation GO:0050865 289 0.029
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.029
forebrain development GO:0030900 302 0.029
leukocyte migration GO:0050900 124 0.029
negative regulation of protein metabolic process GO:0051248 282 0.029
regulation of dendritic cell chemotaxis GO:2000508 1 0.029
axonogenesis GO:0007409 274 0.029
endocytosis GO:0006897 168 0.028
cell adhesion GO:0007155 329 0.028
cyclic nucleotide metabolic process GO:0009187 59 0.028
interleukin 12 secretion GO:0072610 3 0.028
neutrophil migration GO:1990266 37 0.028
leukocyte mediated immunity GO:0002443 174 0.028
g protein coupled receptor signaling pathway GO:0007186 243 0.028
positive regulation of cell development GO:0010720 237 0.028
multicellular organismal signaling GO:0035637 91 0.027
positive regulation of bone remodeling GO:0046852 13 0.027
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.027
peptidyl amino acid modification GO:0018193 336 0.027
regulation of cell motility GO:2000145 236 0.027
regulation of myeloid cell differentiation GO:0045637 96 0.027
positive regulation of lymphocyte activation GO:0051251 140 0.027
positive regulation of homeostatic process GO:0032846 64 0.027
positive regulation of dendritic cell chemotaxis GO:2000510 1 0.027
positive regulation of leukocyte mediated immunity GO:0002705 70 0.027
cell killing GO:0001906 67 0.027
immune response regulating signaling pathway GO:0002764 125 0.027
cytokine production GO:0001816 319 0.026
carbohydrate derivative biosynthetic process GO:1901137 183 0.026
purine ribonucleotide metabolic process GO:0009150 290 0.026
regulation of hematopoietic stem cell migration GO:2000471 1 0.026
angiogenesis GO:0001525 201 0.026
thermosensory behavior GO:0040040 1 0.026
cognition GO:0050890 149 0.025
response to extracellular stimulus GO:0009991 127 0.025
organic cyclic compound catabolic process GO:1901361 295 0.025
regulation of inflammatory response to antigenic stimulus GO:0002861 21 0.025
rho protein signal transduction GO:0007266 32 0.025
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.025
acute inflammatory response to antigenic stimulus GO:0002438 12 0.025
leukocyte differentiation GO:0002521 342 0.025
regulation of chloride transport GO:2001225 2 0.024
neural precursor cell proliferation GO:0061351 121 0.024
response to organic cyclic compound GO:0014070 198 0.024
immune complex clearance GO:0002434 2 0.024
regulation of antigen receptor mediated signaling pathway GO:0050854 29 0.024
negative regulation of macrophage apoptotic process GO:2000110 3 0.024
regulation of cyclic nucleotide metabolic process GO:0030799 40 0.023
macrophage activation GO:0042116 27 0.023
adult behavior GO:0030534 135 0.023
regulation of hormone levels GO:0010817 211 0.023
oxidation reduction process GO:0055114 342 0.023
regulation of homeostatic process GO:0032844 182 0.023
regulation of blood pressure GO:0008217 93 0.023
positive regulation of immune complex clearance by monocytes and macrophages GO:0090265 2 0.023
t cell differentiation GO:0030217 174 0.023
cellular response to cytokine stimulus GO:0071345 189 0.023
lymphocyte differentiation GO:0030098 242 0.023
regulation of angiotensin levels in blood GO:0002002 4 0.022
protein catabolic process GO:0030163 221 0.022
alcohol metabolic process GO:0006066 116 0.022
granulocyte chemotaxis GO:0071621 39 0.022
antigen processing and presentation GO:0019882 47 0.022
response to molecule of bacterial origin GO:0002237 143 0.022
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.022
humoral immune response GO:0006959 57 0.022
Human
lipid biosynthetic process GO:0008610 179 0.021
t cell receptor signaling pathway GO:0050852 46 0.021
fatty acid biosynthetic process GO:0006633 41 0.021
cellular chemical homeostasis GO:0055082 215 0.021
neuron projection guidance GO:0097485 141 0.021
ribonucleotide metabolic process GO:0009259 291 0.021
ras protein signal transduction GO:0007265 77 0.021
macromolecule catabolic process GO:0009057 281 0.021
regulation of leukocyte proliferation GO:0070663 121 0.021
positive regulation of protein phosphorylation GO:0001934 242 0.021
regulation of monocyte chemotaxis GO:0090025 3 0.021
monocarboxylic acid metabolic process GO:0032787 191 0.020
leukocyte degranulation GO:0043299 27 0.020
cytokine mediated signaling pathway GO:0019221 115 0.020
regulation of defense response GO:0031347 233 0.020
organonitrogen compound biosynthetic process GO:1901566 192 0.020
positive regulation of transcription from rna polymerase ii promoter involved in smooth muscle cell differentiation GO:2000721 2 0.020
positive regulation of lymphocyte anergy GO:0002913 4 0.020
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.020
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.020
positive regulation of cell death GO:0010942 224 0.020
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.020
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.020
myeloid leukocyte migration GO:0097529 57 0.019
nucleoside phosphate metabolic process GO:0006753 338 0.019
germ cell development GO:0007281 185 0.019
fat cell differentiation GO:0045444 160 0.019
eosinophil degranulation GO:0043308 1 0.019
glycoprotein biosynthetic process GO:0009101 89 0.019
chemotaxis GO:0006935 247 0.019
carboxylic acid biosynthetic process GO:0046394 86 0.019
regulation of apoptotic signaling pathway GO:2001233 197 0.019
innate immune response activating signal transduction GO:0002758 50 0.019
single organism cell adhesion GO:0098602 156 0.019
metal ion homeostasis GO:0055065 189 0.019
branching morphogenesis of an epithelial tube GO:0048754 159 0.018
regulation of ion transport GO:0043269 215 0.018
purine nucleotide metabolic process GO:0006163 302 0.018
plasma membrane organization GO:0007009 90 0.018
reactive nitrogen species metabolic process GO:2001057 0 0.018
negative regulation of cellular component organization GO:0051129 194 0.018
positive regulation of cell adhesion GO:0045785 80 0.018
extrinsic apoptotic signaling pathway GO:0097191 126 0.018
regulation of chemotaxis GO:0050920 53 0.018
cyclic nucleotide biosynthetic process GO:0009190 44 0.018
regulation of cell projection organization GO:0031344 206 0.018
alpha beta t cell activation GO:0046631 91 0.017
localization within membrane GO:0051668 4 0.017
regulation of acute inflammatory response GO:0002673 27 0.017
transmembrane transport GO:0055085 412 0.017
transmission of nerve impulse GO:0019226 76 0.017
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.017
regulation of inflammatory response GO:0050727 147 0.017
amino acid transport GO:0006865 61 0.017
regulation of macrophage activation GO:0043030 17 0.017
divalent metal ion transport GO:0070838 172 0.017
positive regulation of cell killing GO:0031343 33 0.017
cytoplasmic transport GO:0016482 234 0.017
single organismal cell cell adhesion GO:0016337 131 0.017
positive regulation of monocyte chemotaxis GO:0090026 2 0.017
positive regulation of calcium mediated signaling GO:0050850 15 0.017
positive regulation of lymphocyte proliferation GO:0050671 70 0.017
positive regulation of nervous system development GO:0051962 221 0.016
response to lipopolysaccharide GO:0032496 128 0.016
positive regulation of cytokine production GO:0001819 174 0.016
signal transduction in absence of ligand GO:0038034 55 0.016
axon guidance GO:0007411 141 0.016
cellular ion homeostasis GO:0006873 165 0.016
regulation of nucleotide metabolic process GO:0006140 169 0.016
dendritic spine maintenance GO:0097062 4 0.016
regulation of purine nucleotide metabolic process GO:1900542 169 0.016
acute inflammatory response GO:0002526 41 0.016
regulation of phagocytosis GO:0050764 33 0.016
natural killer cell mediated immunity GO:0002228 29 0.016
lymphocyte proliferation GO:0046651 164 0.016
regulation of t cell proliferation GO:0042129 92 0.016
cellular macromolecule catabolic process GO:0044265 206 0.016
negative thymic t cell selection GO:0045060 12 0.016
negative regulation of vasculature development GO:1901343 26 0.015
small gtpase mediated signal transduction GO:0007264 97 0.015
negative regulation of cell migration GO:0030336 59 0.015
epithelial tube morphogenesis GO:0060562 303 0.015
small molecule biosynthetic process GO:0044283 132 0.015
granulocyte activation GO:0036230 10 0.015
male gamete generation GO:0048232 285 0.015
anion transmembrane transport GO:0098656 71 0.015
positive regulation of neutrophil mediated killing of symbiont cell GO:0070961 1 0.015
chloride transport GO:0006821 32 0.015
multicellular organismal homeostasis GO:0048871 164 0.015
Human
regulation of cell adhesion GO:0030155 154 0.015
regulation of leukocyte mediated immunity GO:0002703 104 0.015
response to peptide hormone GO:0043434 127 0.015
carbohydrate homeostasis GO:0033500 128 0.015
response to oxidative stress GO:0006979 123 0.015
regulation of membrane potential GO:0042391 192 0.014
sequestering of calcium ion GO:0051208 18 0.014
cellular calcium ion homeostasis GO:0006874 119 0.014
cellular carbohydrate metabolic process GO:0044262 119 0.014
inorganic ion transmembrane transport GO:0098660 234 0.014
protein localization to nucleus GO:0034504 121 0.014
anion transport GO:0006820 177 0.014
b cell activation GO:0042113 161 0.014
muscle tissue development GO:0060537 308 0.014
regulation of type 2 immune response GO:0002828 18 0.014
membrane invagination GO:0010324 17 0.014
organic hydroxy compound metabolic process GO:1901615 203 0.014
bone resorption GO:0045453 38 0.014
cellular divalent inorganic cation homeostasis GO:0072503 127 0.014
sulfur compound metabolic process GO:0006790 100 0.014
regulation of cellular component biogenesis GO:0044087 181 0.014
reactive oxygen species metabolic process GO:0072593 84 0.014
regulation of vasculature development GO:1901342 88 0.014
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.014
positive regulation of phagocytosis GO:0050766 26 0.013
cellular metal ion homeostasis GO:0006875 151 0.013
positive regulation of interleukin 2 production GO:0032743 19 0.013
cytosolic calcium ion homeostasis GO:0051480 70 0.013
neuronal action potential GO:0019228 54 0.013
cell cell recognition GO:0009988 44 0.013
leukocyte proliferation GO:0070661 172 0.013
negative regulation of synapse assembly GO:0051964 3 0.013
phagocytosis GO:0006909 66 0.013
positive regulation of kinase activity GO:0033674 155 0.013
morphogenesis of a branching epithelium GO:0061138 193 0.013
regulation of epithelial cell proliferation GO:0050678 141 0.013
substrate dependent cell migration GO:0006929 18 0.013
regulation of organelle organization GO:0033043 289 0.013
carbohydrate metabolic process GO:0005975 230 0.013
negative regulation of immune system process GO:0002683 209 0.013
brown fat cell differentiation GO:0050873 36 0.013
positive regulation of intracellular transport GO:0032388 70 0.013
epithelial cell proliferation GO:0050673 174 0.013
interferon gamma production GO:0032609 67 0.013
mature dendritic cell differentiation GO:0097029 3 0.013
memory GO:0007613 58 0.013
interleukin 2 production GO:0032623 33 0.013
regulation of anatomical structure size GO:0090066 178 0.013
cellular protein catabolic process GO:0044257 155 0.013
negative regulation of phospholipase activity GO:0010519 4 0.013
negative regulation of growth GO:0045926 99 0.013
cation transmembrane transport GO:0098655 266 0.013
microtubule based process GO:0007017 236 0.013
protein localization to organelle GO:0033365 185 0.013
positive regulation of endocytosis GO:0045807 42 0.012
regulation of tissue remodeling GO:0034103 38 0.012
positive regulation of camp mediated signaling GO:0043950 3 0.012
regulation of interleukin 2 production GO:0032663 28 0.012
regulation of cellular catabolic process GO:0031329 242 0.012
cerebral cortex development GO:0021987 86 0.012
positive regulation of response to wounding GO:1903036 66 0.012
positive regulation of cell motility GO:2000147 116 0.012
regulation of hydrolase activity GO:0051336 246 0.012
negative regulation of molecular function GO:0044092 258 0.012
regulation of intracellular transport GO:0032386 159 0.012
regulation of lymphocyte mediated immunity GO:0002706 84 0.012
sensory organ morphogenesis GO:0090596 242 0.012
cytokine biosynthetic process GO:0042089 68 0.012
cerebral cortex cell migration GO:0021795 44 0.012
ribonucleotide biosynthetic process GO:0009260 59 0.012
negative regulation of angiogenesis GO:0016525 25 0.012
engulfment of apoptotic cell GO:0043652 3 0.012
t cell selection GO:0045058 34 0.012
regulation of interferon gamma production GO:0032649 57 0.012
positive thymic t cell selection GO:0045059 13 0.012
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.012
response to drug GO:0042493 75 0.012
renal system development GO:0072001 225 0.012
antigen processing and presentation of exogenous antigen GO:0019884 26 0.012
lipid homeostasis GO:0055088 63 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.012
regulation of lymphocyte differentiation GO:0045619 107 0.012
positive regulation of immune effector process GO:0002699 107 0.012
kidney development GO:0001822 213 0.011
b cell mediated immunity GO:0019724 71 0.011
granulocyte migration GO:0097530 43 0.011
positive regulation of natural killer cell mediated immunity GO:0002717 16 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.011
neuromuscular process GO:0050905 99 0.011
positive regulation of cell migration GO:0030335 109 0.011
regulation of neuron differentiation GO:0045664 281 0.011
peptidyl tyrosine modification GO:0018212 145 0.011
ameboidal type cell migration GO:0001667 128 0.011
positive regulation of lymphocyte differentiation GO:0045621 61 0.011
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.011
positive regulation of apoptotic process GO:0043065 217 0.011
ribonucleoside metabolic process GO:0009119 245 0.011
regulation of lymphocyte proliferation GO:0050670 117 0.011
antibacterial humoral response GO:0019731 8 0.011
Human
nucleoside phosphate catabolic process GO:1901292 222 0.011
positive regulation of map kinase activity GO:0043406 84 0.011
regulation of cd8 positive alpha beta t cell extravasation GO:2000449 3 0.011
glucose homeostasis GO:0042593 128 0.011
mapk cascade GO:0000165 281 0.011
organophosphate catabolic process GO:0046434 232 0.011
nucleoside phosphate biosynthetic process GO:1901293 79 0.011
defense response to bacterium GO:0042742 119 0.011
Human
calcium ion homeostasis GO:0055074 127 0.011
nucleotide biosynthetic process GO:0009165 78 0.011
bone remodeling GO:0046849 53 0.011
inorganic anion transport GO:0015698 43 0.011
extracellular matrix organization GO:0030198 147 0.011
integrin activation GO:0033622 8 0.011
inflammatory response to antigenic stimulus GO:0002437 30 0.011
neutrophil chemotaxis GO:0030593 36 0.011
peptide transport GO:0015833 133 0.011
positive regulation of bone resorption GO:0045780 13 0.011
cell adhesion mediated by integrin GO:0033627 18 0.011
regulation of adaptive immune response GO:0002819 90 0.011
gliogenesis GO:0042063 141 0.011
locomotory behavior GO:0007626 195 0.010
compound eye development GO:0048749 1 0.010
positive regulation of leukocyte proliferation GO:0070665 73 0.010
learning or memory GO:0007611 148 0.010
phagocytosis recognition GO:0006910 12 0.010
steroid metabolic process GO:0008202 119 0.010
sterol metabolic process GO:0016125 58 0.010
regulation of type ii hypersensitivity GO:0002892 4 0.010
exocytosis GO:0006887 121 0.010
negative regulation of cellular amine metabolic process GO:0033239 1 0.010
divalent inorganic cation homeostasis GO:0072507 138 0.010
respiratory system development GO:0060541 190 0.010
regulation of lymphocyte anergy GO:0002911 4 0.010
negative regulation of signal transduction in absence of ligand GO:1901099 16 0.010
positive regulation of type ii hypersensitivity GO:0002894 4 0.010
regulation of reactive oxygen species metabolic process GO:2000377 40 0.010
regulation of cell killing GO:0031341 40 0.010
chromatin organization GO:0006325 206 0.010
regulation of leukocyte differentiation GO:1902105 159 0.010
positive regulation of eosinophil migration GO:2000418 2 0.010
cation homeostasis GO:0055080 212 0.010

Igj disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
hematopoietic system disease DOID:74 0 0.331
immune system disease DOID:2914 0 0.331
disease of anatomical entity DOID:7 0 0.331
primary immunodeficiency disease DOID:612 0 0.059
sensory system disease DOID:0050155 0 0.034
nervous system disease DOID:863 0 0.034
eye and adnexa disease DOID:1492 0 0.034
blood protein disease DOID:620 0 0.032
eye disease DOID:5614 0 0.027
b cell deficiency DOID:2115 0 0.026
retinal disease DOID:5679 0 0.012
retinal degeneration DOID:8466 0 0.012
disease of metabolism DOID:0014667 0 0.012