Mus musculus

0 known processes

Igl

immunoglobulin lambda chain complex

(Aliases: Igl-x,MGC6743)

Igl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein methylation GO:0006479 81 0.330
vestibular receptor cell development GO:0060118 2 0.295
methylation GO:0032259 134 0.209
regulation of b cell mediated immunity GO:0002712 37 0.169
leukocyte differentiation GO:0002521 342 0.164
negative regulation of stem cell maintenance GO:1902455 4 0.160
histone lysine methylation GO:0034968 50 0.151
cellular response to monosaccharide stimulus GO:0071326 47 0.140
macromolecule methylation GO:0043414 120 0.137
adaptive immune response GO:0002250 155 0.127
vestibular reflex GO:0060005 4 0.124
cellular response to acid chemical GO:0071229 68 0.115
response to acid chemical GO:0001101 111 0.111
regulation of cellular ketone metabolic process GO:0010565 66 0.107
lymphocyte mediated immunity GO:0002449 139 0.107
retinal cone cell differentiation GO:0042670 8 0.106
protein alkylation GO:0008213 81 0.105
inner ear receptor cell development GO:0060119 39 0.103
regulation of chromatin modification GO:1903308 57 0.100
mesenchymal cell apoptotic process involved in nephron morphogenesis GO:1901145 4 0.096
cellular response to hexose stimulus GO:0071331 47 0.090
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.090
covalent chromatin modification GO:0016569 163 0.090
negative regulation of protein modification process GO:0031400 163 0.088
eye photoreceptor cell differentiation GO:0001754 41 0.087
positive regulation of metanephric glomerulus development GO:0072300 4 0.085
retina development in camera type eye GO:0060041 119 0.085
positive regulation of adaptive immune response GO:0002821 61 0.085
lymphocyte differentiation GO:0030098 242 0.082
negative regulation of protein metabolic process GO:0051248 282 0.082
response to monosaccharide GO:0034284 67 0.080
neural tube closure GO:0001843 90 0.078
regulation of leukocyte mediated immunity GO:0002703 104 0.078
stem cell maintenance GO:0019827 130 0.076
chromatin organization GO:0006325 206 0.074
cellular response to lipid GO:0071396 145 0.071
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.071
regulation of hormone levels GO:0010817 211 0.071
anatomical structure maturation GO:0071695 49 0.070
regulation of cellular amino acid metabolic process GO:0006521 5 0.070
histone methylation GO:0016571 71 0.070
camera type eye development GO:0043010 266 0.068
primary neural tube formation GO:0014020 95 0.066
cellular modified amino acid metabolic process GO:0006575 63 0.066
histone modification GO:0016570 159 0.065
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.063
b cell mediated immunity GO:0019724 71 0.063
regulation of neuron differentiation GO:0045664 281 0.063
immune effector process GO:0002252 321 0.061
negative regulation of histone methylation GO:0031061 10 0.061
cellular ketone metabolic process GO:0042180 84 0.060
cellular amine metabolic process GO:0044106 44 0.058
regulation of histone modification GO:0031056 56 0.058
chromatin modification GO:0016568 187 0.058
oxidation reduction process GO:0055114 342 0.057
positive regulation of leukocyte mediated immunity GO:0002705 70 0.057
regulation of lymphocyte mediated immunity GO:0002706 84 0.057
nephron tubule development GO:0072080 84 0.054
cellular amino acid metabolic process GO:0006520 103 0.053
positive regulation of type ii hypersensitivity GO:0002894 4 0.053
photoreceptor cell differentiation GO:0046530 52 0.053
positive regulation of b cell mediated immunity GO:0002714 26 0.052
regulation of lymphocyte activation GO:0051249 240 0.052
reactive oxygen species metabolic process GO:0072593 84 0.052
negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072040 4 0.049
skin development GO:0043588 220 0.049
regulation of organelle organization GO:0033043 289 0.049
thyroid hormone generation GO:0006590 7 0.048
negative regulation of organelle organization GO:0010639 90 0.047
regulation of histone methylation GO:0031060 30 0.047
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.045
response to inorganic substance GO:0010035 96 0.045
regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072039 4 0.045
cellular chemical homeostasis GO:0055082 215 0.045
carbohydrate homeostasis GO:0033500 128 0.045
regulation of chromatin organization GO:1902275 57 0.045
positive regulation of cellular amine metabolic process GO:0033240 5 0.044
regulation of defense response GO:0031347 233 0.044
developmental maturation GO:0021700 193 0.044
anatomical structure arrangement GO:0048532 20 0.043
defense response to other organism GO:0098542 197 0.043
regulation of morphogenesis of a branching structure GO:0060688 53 0.043
hormone metabolic process GO:0042445 86 0.043
sensory organ morphogenesis GO:0090596 242 0.043
regulation of thyroid hormone generation GO:2000609 4 0.043
tube closure GO:0060606 91 0.043
negative regulation of kidney development GO:0090185 15 0.042
kidney epithelium development GO:0072073 121 0.041
phenol containing compound metabolic process GO:0018958 60 0.040
tube formation GO:0035148 140 0.040
complement activation GO:0006956 16 0.040
glucose homeostasis GO:0042593 128 0.039
regulation of inflammatory response GO:0050727 147 0.039
protein kinase b signaling GO:0043491 74 0.038
humoral immune response mediated by circulating immunoglobulin GO:0002455 14 0.038
regulation of anatomical structure size GO:0090066 178 0.038
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.038
ear development GO:0043583 200 0.036
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.036
positive regulation of cell development GO:0010720 237 0.036
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.035
immunoglobulin mediated immune response GO:0016064 69 0.035
negative regulation of cell development GO:0010721 169 0.034
response to oxidative stress GO:0006979 123 0.034
macromolecule catabolic process GO:0009057 281 0.034
positive regulation of nervous system development GO:0051962 221 0.034
cellular response to external stimulus GO:0071496 88 0.033
positive regulation of inflammatory response to antigenic stimulus GO:0002863 11 0.033
nephron epithelium morphogenesis GO:0072088 68 0.033
humoral immune response GO:0006959 57 0.033
regulation of mesenchymal cell apoptotic process involved in metanephros development GO:1900211 4 0.032
negative regulation of molecular function GO:0044092 258 0.032
cell type specific apoptotic process GO:0097285 268 0.031
negative regulation of cellular component organization GO:0051129 194 0.031
neural tube development GO:0021915 160 0.031
positive regulation of inflammatory response GO:0050729 47 0.030
dna metabolic process GO:0006259 303 0.030
cellular response to oxidative stress GO:0034599 76 0.030
cellular glucose homeostasis GO:0001678 52 0.029
morphogenesis of embryonic epithelium GO:0016331 159 0.029
hypersensitivity GO:0002524 10 0.029
cranial nerve formation GO:0021603 4 0.029
response to retinoic acid GO:0032526 56 0.029
regulation of chromosome organization GO:0033044 83 0.029
glomerulus development GO:0032835 40 0.028
retina morphogenesis in camera type eye GO:0060042 45 0.028
neural retina development GO:0003407 41 0.028
cd4 positive alpha beta t cell activation GO:0035710 45 0.028
striated muscle tissue development GO:0014706 293 0.028
regulation of cellular amine metabolic process GO:0033238 20 0.027
protein catabolic process GO:0030163 221 0.027
leukocyte proliferation GO:0070661 172 0.027
negative regulation of chromosome organization GO:2001251 30 0.027
renal tubule development GO:0061326 87 0.027
positive regulation of immune effector process GO:0002699 107 0.026
cellular homeostasis GO:0019725 240 0.026
cellular response to biotic stimulus GO:0071216 92 0.026
b cell differentiation GO:0030183 78 0.026
skeletal system development GO:0001501 356 0.026
nerve development GO:0021675 67 0.026
nephron tubule morphogenesis GO:0072078 68 0.026
negative regulation of phosphorus metabolic process GO:0010563 184 0.026
positive regulation of hormone metabolic process GO:0032352 3 0.026
stem cell differentiation GO:0048863 268 0.025
organic hydroxy compound metabolic process GO:1901615 203 0.025
epithelial tube formation GO:0072175 130 0.025
positive regulation of phagocytosis GO:0050766 26 0.025
t cell activation GO:0042110 289 0.024
hair cell differentiation GO:0035315 40 0.024
response to hydrogen peroxide GO:0042542 32 0.024
endoderm development GO:0007492 45 0.024
urogenital system development GO:0001655 261 0.023
regulation of t cell activation GO:0050863 170 0.023
nephron development GO:0072006 109 0.023
regulation of metanephros development GO:0072215 15 0.023
ureter morphogenesis GO:0072197 4 0.023
negative regulation of cellular protein metabolic process GO:0032269 247 0.022
epithelial cell development GO:0002064 159 0.022
vestibulocochlear nerve morphogenesis GO:0021648 4 0.022
optic nerve structural organization GO:0021633 2 0.022
developmental programmed cell death GO:0010623 41 0.022
mesonephric tubule development GO:0072164 94 0.022
protein activation cascade GO:0072376 19 0.021
cellular response to growth factor stimulus GO:0071363 197 0.021
skeletal muscle organ development GO:0060538 163 0.021
dendrite development GO:0016358 115 0.021
lymphocyte apoptotic process GO:0070227 54 0.020
muscle tissue development GO:0060537 308 0.020
thymus development GO:0048538 41 0.020
nephron epithelium development GO:0072009 92 0.020
regulation of protein maturation GO:1903317 96 0.020
regulation of stem cell maintenance GO:2000036 17 0.020
positive regulation of myeloid leukocyte mediated immunity GO:0002888 14 0.020
kidney morphogenesis GO:0060993 83 0.020
regulation of kidney size GO:0035564 3 0.020
mesenchymal cell apoptotic process involved in metanephros development GO:1900200 4 0.020
skeletal system morphogenesis GO:0048705 203 0.020
inner ear morphogenesis GO:0042472 101 0.020
response to reactive oxygen species GO:0000302 56 0.019
positive regulation of thyroid hormone generation GO:2000611 2 0.019
negative regulation of hydrolase activity GO:0051346 71 0.019
lipid transport GO:0006869 98 0.019
purine nucleotide metabolic process GO:0006163 302 0.019
hematopoietic progenitor cell differentiation GO:0002244 143 0.019
response to amino acid GO:0043200 37 0.019
organ maturation GO:0048799 17 0.019
stem cell development GO:0048864 219 0.019
regulation of phagocytosis GO:0050764 33 0.018
regulation of leukocyte proliferation GO:0070663 121 0.018
brain morphogenesis GO:0048854 32 0.018
morphogenesis of a branching epithelium GO:0061138 193 0.018
camera type eye photoreceptor cell differentiation GO:0060219 15 0.018
homeostasis of number of cells GO:0048872 210 0.018
negative regulation of chromatin modification GO:1903309 19 0.018
regulation of response to wounding GO:1903034 189 0.018
lymphocyte homeostasis GO:0002260 64 0.018
thyroid hormone metabolic process GO:0042403 16 0.018
regionalization GO:0003002 337 0.018
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.018
epithelial tube morphogenesis GO:0060562 303 0.018
cell adhesion GO:0007155 329 0.018
dephosphorylation GO:0016311 129 0.018
alpha beta t cell differentiation GO:0046632 69 0.017
cellular response to molecule of bacterial origin GO:0071219 83 0.017
ear morphogenesis GO:0042471 118 0.017
gland development GO:0048732 330 0.017
regulation of apoptotic process involved in morphogenesis GO:1902337 10 0.017
leukocyte homeostasis GO:0001776 79 0.017
carbohydrate derivative catabolic process GO:1901136 231 0.017
regulation of histone h3 k9 methylation GO:0051570 8 0.017
photoreceptor cell fate commitment GO:0046552 2 0.017
regulation of protein processing GO:0070613 96 0.017
regulation of vesicle mediated transport GO:0060627 139 0.017
mesonephric epithelium development GO:0072163 94 0.017
regulation of metanephric glomerulus development GO:0072298 5 0.017
renal system pattern specification GO:0072048 9 0.017
regulation of secretion GO:0051046 274 0.016
protein maturation GO:0051604 176 0.016
regulation of leukocyte apoptotic process GO:2000106 56 0.016
regulation of hydrolase activity GO:0051336 246 0.016
mesonephric tubule morphogenesis GO:0072171 63 0.016
positive regulation of kinase activity GO:0033674 155 0.016
epithelial cell differentiation involved in kidney development GO:0035850 23 0.016
cellular response to amino acid stimulus GO:0071230 29 0.016
bone morphogenesis GO:0060349 78 0.016
posttranscriptional regulation of gene expression GO:0010608 155 0.016
immature b cell differentiation GO:0002327 10 0.015
organic cyclic compound catabolic process GO:1901361 295 0.015
mesenchyme development GO:0060485 152 0.015
peptide hormone secretion GO:0030072 109 0.015
cell recognition GO:0008037 83 0.015
digestive tract development GO:0048565 190 0.015
b cell activation GO:0042113 161 0.015
alpha beta t cell activation GO:0046631 91 0.015
negative regulation of mesenchymal cell apoptotic process involved in metanephros development GO:1900212 4 0.015
cellular response to abiotic stimulus GO:0071214 56 0.015
negative regulation of protein processing GO:0010955 79 0.015
cellular response to lipopolysaccharide GO:0071222 77 0.015
reflex GO:0060004 22 0.015
leukocyte mediated cytotoxicity GO:0001909 62 0.014
regulation of lymphocyte proliferation GO:0050670 117 0.014
regulation of type iia hypersensitivity GO:0001796 4 0.014
skeletal muscle cell differentiation GO:0035914 66 0.014
nephric duct formation GO:0072179 4 0.014
regulation of glomerulus development GO:0090192 6 0.014
regulation of cellular catabolic process GO:0031329 242 0.014
negative regulation of lymphocyte activation GO:0051250 91 0.014
vestibulocochlear nerve formation GO:0021650 2 0.014
mesoderm development GO:0007498 100 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.014
intracellular protein transport GO:0006886 204 0.014
response to molecule of bacterial origin GO:0002237 143 0.014
purine ribonucleotide catabolic process GO:0009154 208 0.014
renal system development GO:0072001 225 0.014
somitogenesis GO:0001756 69 0.014
multicellular organism growth GO:0035264 161 0.014
organ growth GO:0035265 117 0.014
mesonephros development GO:0001823 97 0.013
paramesonephric duct development GO:0061205 3 0.013
mechanoreceptor differentiation GO:0042490 67 0.013
kidney development GO:0001822 213 0.013
regulation of neural retina development GO:0061074 3 0.013
purine ribonucleotide metabolic process GO:0009150 290 0.013
regulation of organ morphogenesis GO:2000027 144 0.013
ureteric bud morphogenesis GO:0060675 62 0.013
histone h3 k9 methylation GO:0051567 17 0.013
regulation of cysteine type endopeptidase activity GO:2000116 65 0.013
pancreas development GO:0031016 57 0.013
sclerotome development GO:0061056 4 0.013
negative regulation of protein phosphorylation GO:0001933 126 0.013
immunoglobulin production GO:0002377 73 0.013
regulation of photoreceptor cell differentiation GO:0046532 4 0.013
glycosyl compound metabolic process GO:1901657 246 0.013
ras protein signal transduction GO:0007265 77 0.013
leukocyte activation involved in immune response GO:0002366 126 0.012
gastrulation GO:0007369 116 0.012
regulation of leukocyte differentiation GO:1902105 159 0.012
positive regulation of glomerulus development GO:0090193 5 0.012
regulation of secretion by cell GO:1903530 249 0.012
regulation of type i hypersensitivity GO:0001810 4 0.012
positive regulation of metanephros development GO:0072216 9 0.012
regulation of metal ion transport GO:0010959 106 0.012
cellular response to organonitrogen compound GO:0071417 145 0.012
mapk cascade GO:0000165 281 0.012
regulation of multi organism process GO:0043900 111 0.012
face morphogenesis GO:0060325 29 0.012
regulation of peptidase activity GO:0052547 96 0.012
ribonucleoside metabolic process GO:0009119 245 0.012
membrane organization GO:0061024 245 0.012
bone development GO:0060348 120 0.012
aromatic compound catabolic process GO:0019439 286 0.012
morphogenesis of a branching structure GO:0001763 203 0.012
regulation of stem cell differentiation GO:2000736 50 0.012
glial cell differentiation GO:0010001 131 0.012
ribonucleoside triphosphate metabolic process GO:0009199 220 0.012
segmentation GO:0035282 93 0.012
negative regulation of cell activation GO:0050866 111 0.012
negative regulation of protein maturation GO:1903318 79 0.012
regulation of t cell proliferation GO:0042129 92 0.012
hair cycle GO:0042633 90 0.012
inner ear receptor cell differentiation GO:0060113 61 0.012
regulation of establishment of protein localization GO:0070201 181 0.011
t cell proliferation GO:0042098 120 0.011
amine metabolic process GO:0009308 45 0.011
carbohydrate metabolic process GO:0005975 230 0.011
response to organonitrogen compound GO:0010243 246 0.011
cranial nerve morphogenesis GO:0021602 26 0.011
digestive system development GO:0055123 200 0.011
cell fate commitment GO:0045165 210 0.011
nucleoside triphosphate catabolic process GO:0009143 205 0.011
ureteric bud development GO:0001657 94 0.011
cell killing GO:0001906 67 0.011
renal vesicle development GO:0072087 17 0.011
response to growth factor GO:0070848 198 0.011
nucleoside catabolic process GO:0009164 206 0.011
positive regulation of protein modification process GO:0031401 299 0.011
nucleotide metabolic process GO:0009117 332 0.011
organonitrogen compound catabolic process GO:1901565 264 0.011
mesoderm morphogenesis GO:0048332 64 0.011
negative regulation of metanephros development GO:0072217 6 0.011
monosaccharide metabolic process GO:0005996 106 0.011
nucleobase containing small molecule metabolic process GO:0055086 352 0.011
regulation of membrane potential GO:0042391 192 0.011
regulation of gtp catabolic process GO:0033124 113 0.011
negative regulation of intracellular signal transduction GO:1902532 167 0.011
mesenchymal cell differentiation GO:0048762 107 0.011
t cell differentiation GO:0030217 174 0.011
inorganic ion transmembrane transport GO:0098660 234 0.011
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.011
embryonic organ morphogenesis GO:0048562 276 0.010
regulation of metanephros size GO:0035566 2 0.010
embryonic epithelial tube formation GO:0001838 130 0.010
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.010
interleukin 10 secretion GO:0072608 4 0.010
rho protein signal transduction GO:0007266 32 0.010
regulation of ion transmembrane transport GO:0034765 119 0.010
cellular nitrogen compound catabolic process GO:0044270 280 0.010
positive regulation of lymphocyte activation GO:0051251 140 0.010
regulation of retina development in camera type eye GO:1902866 3 0.010
cell differentiation involved in metanephros development GO:0072202 12 0.010
optic nerve development GO:0021554 8 0.010
phagocytosis recognition GO:0006910 12 0.010
dna repair GO:0006281 107 0.010
regulation of endocytosis GO:0030100 69 0.010
leukocyte mediated immunity GO:0002443 174 0.010
dct cell differentiation GO:0072069 3 0.010

Igl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
organ system cancer DOID:0050686 0 0.193
disease of cellular proliferation DOID:14566 0 0.193
cancer DOID:162 0 0.193
leukemia DOID:1240 0 0.102
immune system cancer DOID:0060083 0 0.102
hematologic cancer DOID:2531 0 0.102
nervous system disease DOID:863 0 0.016
disease of anatomical entity DOID:7 0 0.016