Mus musculus

340 known processes

Ihh

Indian hedgehog

Ihh biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
paraxial mesodermal cell differentiation GO:0048342 2 0.848
endocrine system development GO:0035270 98 0.842
Mouse
trachea cartilage morphogenesis GO:0060535 4 0.828
paraxial mesodermal cell fate commitment GO:0048343 2 0.815
regionalization GO:0003002 337 0.788
Mouse Fly
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.743
negative regulation of sterol transport GO:0032372 4 0.739
Mouse
regulation of body fluid levels GO:0050878 162 0.713
Mouse
regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072039 4 0.626
kidney development GO:0001822 213 0.595
Mouse
central nervous system neuron differentiation GO:0021953 162 0.577
Mouse Fly
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.572
sulfur compound metabolic process GO:0006790 100 0.565
renal vesicle induction GO:0072034 3 0.559
nephric duct formation GO:0072179 4 0.538
carbon catabolite repression of transcription from rna polymerase ii promoter GO:0000437 1 0.504
cellular response to organonitrogen compound GO:0071417 145 0.496
neural tube patterning GO:0021532 43 0.472
Mouse
digestive tract morphogenesis GO:0048546 147 0.460
endodermal cell fate determination GO:0007493 2 0.426
planar cell polarity pathway involved in pericardium morphogenesis GO:0061354 2 0.422
sensory perception GO:0007600 245 0.403
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.391
diencephalon development GO:0021536 63 0.390
Mouse
regulation of organ morphogenesis GO:2000027 144 0.388
Mouse
planar cell polarity pathway involved in ventricular septum morphogenesis GO:0061348 2 0.381
planar cell polarity pathway involved in cardiac right atrium morphogenesis GO:0061349 2 0.372
steroid metabolic process GO:0008202 119 0.362
Mouse
proteoglycan metabolic process GO:0006029 38 0.360
blood vessel morphogenesis GO:0048514 285 0.359
connective tissue development GO:0061448 179 0.354
mesonephric duct morphogenesis GO:0072180 4 0.344
nucleoside phosphate biosynthetic process GO:1901293 79 0.336
skeletal system development GO:0001501 356 0.333
pituitary gland development GO:0021983 38 0.333
nitrogen compound transport GO:0071705 271 0.326
gland development GO:0048732 330 0.318
Mouse
nephron tubule morphogenesis GO:0072078 68 0.317
Mouse
response to extracellular stimulus GO:0009991 127 0.313
skeletal system morphogenesis GO:0048705 203 0.308
planar cell polarity pathway involved in outflow tract morphogenesis GO:0061347 2 0.301
spinal cord development GO:0021510 81 0.300
Zebrafish Mouse
ribonucleotide biosynthetic process GO:0009260 59 0.296
nephron epithelium morphogenesis GO:0072088 68 0.296
Mouse
mesonephric duct formation GO:0072181 2 0.294
peptide secretion GO:0002790 114 0.293
renal inner medulla development GO:0072053 3 0.291
purine nucleotide metabolic process GO:0006163 302 0.282
ribonucleotide metabolic process GO:0009259 291 0.279
ventral midline development GO:0007418 4 0.274
Fly
hypophysis morphogenesis GO:0048850 3 0.272
peptide transport GO:0015833 133 0.271
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 4 0.269
cellular response to organic cyclic compound GO:0071407 87 0.267
hematopoietic progenitor cell differentiation GO:0002244 143 0.262
Mouse
negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072040 4 0.261
cerebral cortex development GO:0021987 86 0.260
polarity specification of proximal distal axis GO:0010085 2 0.255
androgen biosynthetic process GO:0006702 4 0.255
adenohypophysis development GO:0021984 14 0.255
regulation of testosterone biosynthetic process GO:2000224 2 0.252
pyramidal neuron migration GO:0021852 1 0.250
divalent inorganic cation transport GO:0072511 178 0.250
midbrain hindbrain boundary maturation GO:0021732 1 0.247
negative regulation of prostatic bud formation GO:0060686 4 0.247
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.243
cellular homeostasis GO:0019725 240 0.242
primary prostatic bud elongation GO:0060516 2 0.240
Mouse
tertiary branching involved in mammary gland duct morphogenesis GO:0060748 3 0.240
positive regulation of cell development GO:0010720 237 0.240
Mouse
nucleoside phosphate metabolic process GO:0006753 338 0.238
subpallium neuron fate commitment GO:0060163 2 0.237
metanephric nephron tubule formation GO:0072289 4 0.236
mesoderm morphogenesis GO:0048332 64 0.236
digestive tract development GO:0048565 190 0.234
insulin secretion GO:0030073 89 0.233
inner ear morphogenesis GO:0042472 101 0.232
muscle cell differentiation GO:0042692 261 0.232
Zebrafish Mouse
response to organic cyclic compound GO:0014070 198 0.231
ureteric bud morphogenesis GO:0060675 62 0.230
Mouse
pallium development GO:0021543 120 0.227
metanephric loop of henle development GO:0072236 4 0.225
epithelial cell development GO:0002064 159 0.222
mesenchymal cell development GO:0014031 93 0.221
Mouse
testosterone biosynthetic process GO:0061370 2 0.219
regulation of sterol transport GO:0032371 17 0.217
Mouse
regulation of fibroblast growth factor production GO:0090270 4 0.216
axis elongation GO:0003401 30 0.215
Mouse
response to fibroblast growth factor GO:0071774 47 0.214
Fly
midbrain hindbrain boundary maturation during brain development GO:0022004 1 0.213
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.211
cardiac right atrium morphogenesis GO:0003213 3 0.211
digestive system development GO:0055123 200 0.207
chondrocyte differentiation GO:0002062 72 0.206
ribose phosphate metabolic process GO:0019693 291 0.206
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.205
formation of primary germ layer GO:0001704 77 0.204
tissue remodeling GO:0048771 102 0.203
intestinal epithelial cell maturation GO:0060574 2 0.203
anion transport GO:0006820 177 0.203
ras protein signal transduction GO:0007265 77 0.203
somatotropin secreting cell differentiation GO:0060126 4 0.200
lipid transport GO:0006869 98 0.198
Mouse
alcohol metabolic process GO:0006066 116 0.196
mesenchymal cell apoptotic process involved in nephron morphogenesis GO:1901145 4 0.194
hair cycle GO:0042633 90 0.194
Mouse
purine ribonucleotide biosynthetic process GO:0009152 59 0.191
placenta development GO:0001890 140 0.189
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.188
Fly
blastocyst development GO:0001824 80 0.187
response to monosaccharide GO:0034284 67 0.185
morphogenesis of a branching structure GO:0001763 203 0.185
forebrain development GO:0030900 302 0.184
Mouse Fly
androgen metabolic process GO:0008209 11 0.183
Mouse
lateral sprouting involved in mammary gland duct morphogenesis GO:0060599 2 0.183
cell adhesion GO:0007155 329 0.182
renal system development GO:0072001 225 0.181
Mouse
lung epithelium development GO:0060428 37 0.180
Mouse
prostate gland morphogenetic growth GO:0060737 4 0.177
Mouse
establishment of organ orientation GO:0048561 1 0.176
ribose phosphate biosynthetic process GO:0046390 59 0.176
columnar cuboidal epithelial cell development GO:0002066 29 0.174
positive regulation of transcription from rna polymerase ii promoter by glucose GO:0000432 3 0.174
mesenchyme morphogenesis GO:0072132 32 0.174
hindbrain development GO:0030902 128 0.173
Mouse
cation transport GO:0006812 399 0.172
regulation of chondrocyte differentiation GO:0032330 33 0.171
regulation of morphogenesis of a branching structure GO:0060688 53 0.169
Mouse
endoderm development GO:0007492 45 0.168
hindbrain formation GO:0021576 1 0.167
blastocyst formation GO:0001825 33 0.167
morphogenesis of an epithelial fold GO:0060571 28 0.166
Mouse
central nervous system vasculogenesis GO:0022009 3 0.163
negative regulation of hormone metabolic process GO:0032351 4 0.159
gastrulation GO:0007369 116 0.158
plasma membrane organization GO:0007009 90 0.158
respiratory tube development GO:0030323 167 0.157
Mouse
response to nutrient levels GO:0031667 109 0.157
positive regulation of smoothened signaling pathway GO:0045880 23 0.157
planar cell polarity pathway involved in heart morphogenesis GO:0061346 3 0.156
epithelial cell maturation involved in prostate gland development GO:0060743 4 0.154
mesodermal cell differentiation GO:0048333 22 0.150
glandular epithelial cell differentiation GO:0002067 38 0.150
limbic system development GO:0021761 72 0.150
peptide hormone secretion GO:0030072 109 0.146
forebrain morphogenesis GO:0048853 17 0.146
membrane organization GO:0061024 245 0.146
nucleotide biosynthetic process GO:0009165 78 0.146
outer medullary collecting duct development GO:0072060 1 0.144
sensory organ morphogenesis GO:0090596 242 0.143
prostate gland epithelium morphogenesis GO:0060740 31 0.142
Mouse
forebrain generation of neurons GO:0021872 63 0.142
regulation of hormone levels GO:0010817 211 0.141
Mouse
wound healing GO:0042060 157 0.141
Mouse
regulation of ketone biosynthetic process GO:0010566 2 0.141
spemann organizer formation at the anterior end of the primitive streak GO:0060064 1 0.141
inner medullary collecting duct development GO:0072061 2 0.140
nephron tubule development GO:0072080 84 0.140
Mouse
amide transport GO:0042886 138 0.140
regulation of epithelial cell proliferation GO:0050678 141 0.140
Mouse
epithelial cell proliferation GO:0050673 174 0.140
Mouse
regulation of secretion GO:0051046 274 0.139
organic cyclic compound catabolic process GO:1901361 295 0.138
negative regulation of apoptotic process involved in outflow tract morphogenesis GO:1902257 2 0.138
bmp signaling pathway GO:0030509 93 0.138
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.138
establishment of planar polarity involved in nephron morphogenesis GO:0072046 1 0.138
positive regulation of mapk cascade GO:0043410 170 0.137
purine ribonucleoside metabolic process GO:0046128 241 0.137
response to growth factor GO:0070848 198 0.136
Fly
prostate gland morphogenesis GO:0060512 32 0.136
Mouse
lung morphogenesis GO:0060425 50 0.134
Mouse
nephrogenic mesenchyme development GO:0072076 3 0.134
lung induction GO:0060492 3 0.134
blood circulation GO:0008015 195 0.134
steroid biosynthetic process GO:0006694 47 0.133
Mouse
small gtpase mediated signal transduction GO:0007264 97 0.133
axis elongation involved in somitogenesis GO:0090245 4 0.133
floor plate morphogenesis GO:0033505 3 0.133
angiogenesis GO:0001525 201 0.132
cochlea morphogenesis GO:0090103 22 0.132
regulation of hormone secretion GO:0046883 88 0.132
nucleotide metabolic process GO:0009117 332 0.131
positive regulation of cartilage development GO:0061036 18 0.130
positive regulation of transcription from rna polymerase iii promoter GO:0045945 1 0.130
circulatory system process GO:0003013 197 0.130
oligodendrocyte differentiation GO:0048709 53 0.129
Zebrafish Mouse
kidney morphogenesis GO:0060993 83 0.129
Mouse
spinal cord association neuron differentiation GO:0021527 14 0.127
apoptotic process involved in outflow tract morphogenesis GO:0003275 2 0.127
oocyte differentiation GO:0009994 35 0.127
cell fate specification GO:0001708 72 0.126
ureteric bud development GO:0001657 94 0.125
Mouse
regulation of mapk cascade GO:0043408 248 0.123
neuron projection guidance GO:0097485 141 0.123
Mouse
rho protein signal transduction GO:0007266 32 0.123
transmembrane transport GO:0055085 412 0.123
positive regulation of interleukin 8 secretion GO:2000484 1 0.122
t cell differentiation in thymus GO:0033077 77 0.122
purine containing compound metabolic process GO:0072521 311 0.121
glycosyl compound metabolic process GO:1901657 246 0.120
renal capsule morphogenesis GO:0072128 1 0.120
positive regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation GO:2000081 1 0.119
purine containing compound biosynthetic process GO:0072522 70 0.119
response to organonitrogen compound GO:0010243 246 0.118
carbon catabolite activation of transcription GO:0045991 4 0.118
organic acid transport GO:0015849 101 0.118
regulation of reproductive process GO:2000241 66 0.118
Mouse
urate transport GO:0015747 1 0.117
mammary gland epithelium development GO:0061180 65 0.116
negative regulation of cholesterol transport GO:0032375 4 0.116
Mouse
cellular response to nutrient levels GO:0031669 64 0.115
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.115
Fly
adult locomotory behavior GO:0008344 91 0.115
regulation of stem cell proliferation GO:0072091 78 0.115
stem cell development GO:0048864 219 0.115
Mouse
regulation of metal ion transport GO:0010959 106 0.114
cervix development GO:0060067 2 0.114
central nervous system morphogenesis GO:0021551 2 0.113
mammary gland morphogenesis GO:0060443 54 0.113
organic hydroxy compound transport GO:0015850 93 0.113
Mouse
skin morphogenesis GO:0043589 38 0.111
Mouse
spemann organizer formation GO:0060061 2 0.111
primary neural tube formation GO:0014020 95 0.111
adult behavior GO:0030534 135 0.111
epithelial to mesenchymal transition GO:0001837 47 0.110
axonogenesis GO:0007409 274 0.108
Mouse Fly
lung cell differentiation GO:0060479 30 0.108
somatic sex determination GO:0018993 2 0.108
stem cell differentiation GO:0048863 268 0.108
Mouse
response to peptide hormone GO:0043434 127 0.106
regulation of kidney development GO:0090183 40 0.106
Mouse
hormone secretion GO:0046879 128 0.106
regulation of bmp signaling pathway GO:0030510 60 0.106
purine nucleotide biosynthetic process GO:0006164 65 0.106
kidney rudiment formation GO:0072003 3 0.105
cellular response to lipid GO:0071396 145 0.105
blastoderm segmentation GO:0007350 13 0.104
Fly
bone development GO:0060348 120 0.104
sensory perception of sound GO:0007605 97 0.103
endodermal cell fate specification GO:0001714 4 0.103
cellular response to monosaccharide stimulus GO:0071326 47 0.102
cellular response to follicle stimulating hormone stimulus GO:0071372 1 0.102
establishment of anatomical structure orientation GO:0048560 1 0.102
ear development GO:0043583 200 0.100
Mouse
prostate gland stromal morphogenesis GO:0060741 2 0.100
cerebellum formation GO:0021588 1 0.099
carbon catabolite regulation of transcription from rna polymerase ii promoter GO:0000429 4 0.099
positive regulation of transcription by glucose GO:0046016 3 0.099
notch signaling pathway GO:0007219 71 0.098
apoptotic process involved in morphogenesis GO:0060561 25 0.097
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.097
carbohydrate derivative biosynthetic process GO:1901137 183 0.097
ion transmembrane transport GO:0034220 361 0.095
cell differentiation in spinal cord GO:0021515 53 0.094
Zebrafish Mouse
regulation of cartilage development GO:0061035 44 0.094
nucleobase containing small molecule metabolic process GO:0055086 352 0.093
cell type specific apoptotic process GO:0097285 268 0.093
Mouse
calcium ion transport GO:0006816 159 0.092
regulation of cellular amine metabolic process GO:0033238 20 0.092
cyclic nucleotide biosynthetic process GO:0009190 44 0.092
non canonical wnt signaling pathway involved in heart development GO:0061341 3 0.092
cell substrate adhesion GO:0031589 130 0.092
embryonic epithelial tube formation GO:0001838 130 0.091
protein processing GO:0016485 163 0.091
Mouse Fly
cellular response to glucose stimulus GO:0071333 45 0.091
primitive streak formation GO:0090009 10 0.090
oocyte development GO:0048599 33 0.090
cellular response to starvation GO:0009267 57 0.090
urogenital system development GO:0001655 261 0.089
Mouse
negative regulation of apoptotic signaling pathway GO:2001234 104 0.089
regulation of apoptotic signaling pathway GO:2001233 197 0.089
renal sodium excretion GO:0035812 3 0.089
lipid biosynthetic process GO:0008610 179 0.088
Mouse
negative regulation of epithelial cell proliferation GO:0050680 64 0.088
cell junction assembly GO:0034329 52 0.088
divalent metal ion transport GO:0070838 172 0.088
appendage morphogenesis GO:0035107 149 0.088
Mouse
negative regulation of reproductive process GO:2000242 31 0.088
positive regulation of transcription initiation from rna polymerase ii promoter GO:0060261 5 0.088
organonitrogen compound biosynthetic process GO:1901566 192 0.088
cholesterol transport GO:0030301 38 0.087
Mouse
cellular divalent inorganic cation homeostasis GO:0072503 127 0.087
cellular macromolecule catabolic process GO:0044265 206 0.087
Mouse
cyclic purine nucleotide metabolic process GO:0052652 43 0.086
foregut regionalization GO:0060423 3 0.086
negative regulation of stem cell maintenance GO:1902455 4 0.086
oviduct development GO:0060066 3 0.086
renal tubule development GO:0061326 87 0.086
Mouse
nucleoside metabolic process GO:0009116 246 0.085
cellular response to hexose stimulus GO:0071331 47 0.085
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.085
purine ribonucleotide metabolic process GO:0009150 290 0.084
inflammatory response GO:0006954 244 0.083
midgut development GO:0007494 4 0.083
negative regulation of cell cycle GO:0045786 123 0.083
trachea cartilage development GO:0060534 8 0.082
inorganic cation transmembrane transport GO:0098662 207 0.082
nucleoside catabolic process GO:0009164 206 0.082
pancreas development GO:0031016 57 0.082
response to peptide GO:1901652 136 0.082
protein maturation GO:0051604 176 0.081
Mouse Fly
regulation of transcription from rna polymerase ii promoter involved in ventral spinal cord interneuron specification GO:0021913 4 0.081
endocrine pancreas development GO:0031018 29 0.081
response to acid chemical GO:0001101 111 0.081
mesonephric tubule formation GO:0072172 11 0.080
oxygen homeostasis GO:0032364 2 0.080
regulation of peptidase activity GO:0052547 96 0.080
mesoderm formation GO:0001707 62 0.079
cardiac muscle tissue development GO:0048738 130 0.079
lung epithelial cell differentiation GO:0060487 29 0.079
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.079
lung field specification GO:0060424 3 0.079
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.078
Mouse Fly
cell migration involved in gastrulation GO:0042074 13 0.078
cellular response to growth factor stimulus GO:0071363 197 0.078
Fly
posttranscriptional regulation of gene expression GO:0010608 155 0.078
g protein coupled receptor signaling pathway GO:0007186 243 0.078
cell cell junction organization GO:0045216 72 0.078
axial mesoderm formation GO:0048320 3 0.077
ubiquitin dependent smad protein catabolic process GO:0030579 2 0.077
organic anion transport GO:0015711 137 0.077
epithelial tube formation GO:0072175 130 0.077
forebrain regionalization GO:0021871 25 0.076
Mouse
cellular chemical homeostasis GO:0055082 215 0.076
cellular ketone metabolic process GO:0042180 84 0.075
regulation of peptide secretion GO:0002791 77 0.075
neural tube development GO:0021915 160 0.075
Mouse
telencephalon development GO:0021537 186 0.075
Mouse Fly
homeostasis of number of cells GO:0048872 210 0.074
ketone biosynthetic process GO:0042181 8 0.074
regulation of cell motility GO:2000145 236 0.074
Mouse Fly
cellular amide metabolic process GO:0043603 58 0.074
hepaticobiliary system development GO:0061008 67 0.074
muscle tissue morphogenesis GO:0060415 53 0.074
mammary gland duct morphogenesis GO:0060603 38 0.074
trachea development GO:0060438 18 0.073
Mouse
maintenance of cell number GO:0098727 3 0.073
astrocyte fate commitment GO:0060018 4 0.073
regulation of endodermal cell differentiation GO:1903224 2 0.073
prostate epithelial cord elongation GO:0060523 3 0.073
Mouse
cartilage development GO:0051216 140 0.073
cyclic nucleotide metabolic process GO:0009187 59 0.071
limb development GO:0060173 166 0.071
Mouse
developmental growth involved in morphogenesis GO:0060560 138 0.071
Mouse
neuroblast proliferation GO:0007405 49 0.071
Mouse
negative regulation of synapse assembly GO:0051964 3 0.070
establishment of endothelial blood brain barrier GO:0014045 3 0.070
purine nucleoside triphosphate catabolic process GO:0009146 203 0.070
neuron fate specification GO:0048665 30 0.069
response to molecule of bacterial origin GO:0002237 143 0.069
cell fate specification involved in pattern specification GO:0060573 11 0.068
endoderm formation GO:0001706 20 0.068
female somatic sex determination GO:0019101 1 0.068
canonical wnt signaling pathway involved in regulation of cell proliferation GO:0044340 3 0.068
brain segmentation GO:0035284 3 0.068
regulation of steroid metabolic process GO:0019218 39 0.067
Mouse
otic placode formation GO:0043049 1 0.067
regulation of renal sodium excretion GO:0035813 3 0.067
epithelial mesenchymal signaling involved in prostate gland development GO:0060738 2 0.067
Mouse
renal vesicle formation GO:0072033 8 0.065
positive regulation of cell motility GO:2000147 116 0.065
anion transmembrane transport GO:0098656 71 0.065
cardiac ventricle morphogenesis GO:0003208 50 0.065
apoptotic signaling pathway GO:0097190 306 0.064
Mouse
epithelial tube branching involved in lung morphogenesis GO:0060441 28 0.064
Mouse
apoptotic process involved in patterning of blood vessels GO:1902262 6 0.064
striated muscle cell development GO:0055002 125 0.064
Zebrafish
granulosa cell differentiation GO:0060014 1 0.063
ectoderm formation GO:0001705 3 0.063
nephron morphogenesis GO:0072028 69 0.063
Mouse
determination of left right symmetry GO:0007368 80 0.063
regulation of transcription from rna polymerase ii promoter by glucose GO:0000430 3 0.063
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.062
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.062
Mouse Fly
response to starvation GO:0042594 65 0.062
metanephric capsule specification GO:0072267 1 0.061
positive regulation of protein modification process GO:0031401 299 0.061
regulation of cell substrate adhesion GO:0010810 73 0.061
positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0072108 3 0.061
leukocyte migration GO:0050900 124 0.060
regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation GO:2000079 1 0.060
regulation of ras protein signal transduction GO:0046578 114 0.060
paraxial mesoderm morphogenesis GO:0048340 10 0.060
embryonic placenta development GO:0001892 98 0.060
muscle cell proliferation GO:0033002 52 0.060
Mouse
smoothened signaling pathway GO:0007224 105 0.059
regulation of cellular catabolic process GO:0031329 242 0.059
Mouse
hair follicle development GO:0001942 85 0.059
Mouse
regulation of anagen GO:0051884 1 0.059
cardiac ventricle development GO:0003231 83 0.059
positive regulation of auditory receptor cell differentiation GO:0045609 1 0.059
mapk cascade GO:0000165 281 0.058
dna templated transcriptional preinitiation complex assembly GO:0070897 4 0.058
positive regulation of chondrocyte differentiation GO:0032332 13 0.058
embryonic appendage morphogenesis GO:0035113 126 0.058
Mouse
cation transmembrane transport GO:0098655 266 0.058
metanephros development GO:0001656 79 0.058
Mouse
embryonic skeletal system morphogenesis GO:0048704 91 0.058
tube formation GO:0035148 140 0.057
Mouse
positive regulation of cell migration GO:0030335 109 0.057
cardiac chamber development GO:0003205 108 0.057
molting cycle GO:0042303 90 0.057
Mouse Worm
neurotransmitter transport GO:0006836 76 0.057
endodermal digestive tract morphogenesis GO:0061031 4 0.057
positive regulation of neuroblast proliferation GO:0002052 19 0.057
Mouse
cellular glucose homeostasis GO:0001678 52 0.057
lung development GO:0030324 164 0.057
Mouse
cellular amino acid metabolic process GO:0006520 103 0.057
positive regulation of lymphocyte activation GO:0051251 140 0.057
c21 steroid hormone biosynthetic process GO:0006700 3 0.057
gas homeostasis GO:0033483 3 0.056
male gamete generation GO:0048232 285 0.056
Mouse
negative regulation of bmp signaling pathway GO:0030514 35 0.056
negative regulation of cell proliferation GO:0008285 296 0.056
cellular response to extracellular stimulus GO:0031668 81 0.056
metanephric capsule formation GO:0072266 1 0.056
purine ribonucleotide catabolic process GO:0009154 208 0.055
hemostasis GO:0007599 78 0.055
Mouse
epidermis development GO:0008544 187 0.055
Mouse
female sex determination GO:0030237 1 0.055
digestion GO:0007586 40 0.055
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.055
positive regulation of hh target transcription factor activity GO:0007228 3 0.055
Mouse Fly
negative regulation of cell development GO:0010721 169 0.055
positive regulation of stress activated mapk cascade GO:0032874 48 0.055
cellular amine metabolic process GO:0044106 44 0.054
cellular response to peptide hormone stimulus GO:0071375 92 0.054
epithelial tube morphogenesis GO:0060562 303 0.054
learning or memory GO:0007611 148 0.054
cellular ion homeostasis GO:0006873 165 0.054
cellular response to cytokine stimulus GO:0071345 189 0.054
mesoderm development GO:0007498 100 0.054
Mouse Fly
mesonephros development GO:0001823 97 0.054
Mouse
prostate gland development GO:0030850 48 0.054
Mouse
specification of organ position GO:0010159 3 0.054
negative regulation of transcription from rna polymerase ii promoter by glucose GO:0000433 1 0.054
cellular response to external stimulus GO:0071496 88 0.054
notochord development GO:0030903 20 0.053
branching morphogenesis of an epithelial tube GO:0048754 159 0.053
cellular response to carbohydrate stimulus GO:0071322 50 0.053
mesenchymal stem cell maintenance involved in nephron morphogenesis GO:0072038 7 0.053
response to transforming growth factor beta GO:0071559 88 0.053
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway GO:0051482 4 0.053
regulation of proteolysis GO:0030162 164 0.052
Mouse Fly
lung associated mesenchyme development GO:0060484 10 0.052
Mouse
positive regulation of cellular amine metabolic process GO:0033240 5 0.052
nodal signaling pathway involved in determination of left right asymmetry GO:0038107 2 0.052
regulation of transferase activity GO:0051338 263 0.052
forebrain cell migration GO:0021885 58 0.052
cellular response to insulin stimulus GO:0032869 78 0.051
axial mesodermal cell fate commitment GO:0048322 1 0.051
renal capsule formation GO:0072129 1 0.051
kidney epithelium development GO:0072073 121 0.051
Mouse
carboxylic acid transport GO:0046942 100 0.051
regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation GO:2000702 1 0.051
establishment or maintenance of cell polarity GO:0007163 86 0.051
Mouse
endomembrane system organization GO:0010256 147 0.051
neuron apoptotic process GO:0051402 142 0.051
embryonic skeletal system development GO:0048706 120 0.051
renal capsule specification GO:0072130 1 0.051
learning GO:0007612 98 0.051
protein localization to membrane GO:0072657 108 0.051
establishment of tissue polarity GO:0007164 28 0.050
mesonephric duct development GO:0072177 5 0.050
alcohol biosynthetic process GO:0046165 43 0.050
cytoplasmic transport GO:0016482 234 0.050
Mouse Fly
hippocampus development GO:0021766 52 0.050
neuron migration GO:0001764 122 0.050
regulation of lipid transport GO:0032368 36 0.050
Mouse
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development GO:0060528 4 0.050
negative regulation of nervous system development GO:0051961 156 0.049
glucose homeostasis GO:0042593 128 0.049
mammary gland branching involved in pregnancy GO:0060745 6 0.049
regulation of smoothened signaling pathway GO:0008589 58 0.049
smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation GO:0021938 4 0.049
Mouse
nephron development GO:0072006 109 0.049
Mouse
negative regulation of inflammatory response GO:0050728 61 0.049
ear morphogenesis GO:0042471 118 0.049
cellular calcium ion homeostasis GO:0006874 119 0.048
skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration GO:0014834 3 0.048
respiratory system development GO:0060541 190 0.048
Mouse Fly
regulation of stress activated mapk cascade GO:0032872 69 0.048
morphogenesis of a branching epithelium GO:0061138 193 0.048
glomerular mesangial cell development GO:0072144 3 0.048
organic hydroxy compound biosynthetic process GO:1901617 77 0.048
regulation of neural precursor cell proliferation GO:2000177 70 0.048
Mouse
positive regulation of branching involved in lung morphogenesis GO:0061047 4 0.048
oligodendrocyte development GO:0014003 20 0.047
Mouse
cell differentiation in hindbrain GO:0021533 24 0.047

Ihh disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
bone disease DOID:0080001 0 0.698
disease of anatomical entity DOID:7 0 0.698
musculoskeletal system disease DOID:17 0 0.698
connective tissue disease DOID:65 0 0.698
osteochondrodysplasia DOID:2256 0 0.336
bone development disease DOID:0080006 0 0.336