|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.998
|
|
|
|
somatic diversification of immune receptors
|
GO:0002200 |
53 |
0.998
|
|
|
|
regulation of mhc class ii biosynthetic process
|
GO:0045346 |
7 |
0.997
|
|
|
|
interleukin 6 biosynthetic process
|
GO:0042226 |
12 |
0.996
|
Mouse |
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.996
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.996
|
|
|
|
cellular response to interleukin 18
|
GO:0071351 |
3 |
0.996
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.995
|
|
|
|
innate immune response activating cell surface receptor signaling pathway
|
GO:0002220 |
4 |
0.994
|
|
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
45 |
0.994
|
|
|
|
positive regulation of b cell mediated immunity
|
GO:0002714 |
26 |
0.994
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.992
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.992
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.991
|
|
|
|
regulation of inflammatory response to antigenic stimulus
|
GO:0002861 |
21 |
0.991
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
68 |
0.991
|
|
|
|
interleukin 18 production
|
GO:0032621 |
4 |
0.991
|
|
|
|
regulation of growth of symbiont in host
|
GO:0044126 |
19 |
0.989
|
|
|
|
regulation of activated t cell proliferation
|
GO:0046006 |
16 |
0.988
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.988
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.987
|
|
|
|
positive regulation of isotype switching to igg isotypes
|
GO:0048304 |
7 |
0.986
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.986
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.984
|
|
|
|
interleukin 18 mediated signaling pathway
|
GO:0035655 |
2 |
0.984
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.984
|
|
|
|
negative regulation of growth of symbiont in host
|
GO:0044130 |
19 |
0.984
|
|
|
|
somatic recombination of immunoglobulin gene segments
|
GO:0016447 |
42 |
0.982
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.982
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.981
|
|
|
|
somatic diversification of immunoglobulins involved in immune response
|
GO:0002208 |
36 |
0.980
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.975
|
|
|
|
negative regulation of inflammatory response to antigenic stimulus
|
GO:0002862 |
10 |
0.973
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.972
|
|
|
|
dna recombination
|
GO:0006310 |
92 |
0.971
|
|
|
|
regulation of chronic inflammatory response to antigenic stimulus
|
GO:0002874 |
3 |
0.969
|
|
|
|
positive regulation of mhc class ii biosynthetic process
|
GO:0045348 |
4 |
0.966
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.966
|
Mouse |
|
|
somatic recombination of immunoglobulin genes involved in immune response
|
GO:0002204 |
36 |
0.965
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.962
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.962
|
Mouse |
|
|
positive regulation by symbiont of defense related host nitric oxide production
|
GO:0052347 |
1 |
0.961
|
|
|
|
antibacterial peptide production
|
GO:0002778 |
2 |
0.961
|
|
|
|
b cell activation involved in immune response
|
GO:0002312 |
50 |
0.955
|
|
|
|
induction by organism of immune response of other organism involved in symbiotic interaction
|
GO:0052558 |
1 |
0.952
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.951
|
|
|
|
lipopolysaccharide mediated signaling pathway
|
GO:0031663 |
25 |
0.950
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.950
|
|
|
|
positive regulation of activated t cell proliferation
|
GO:0042104 |
8 |
0.949
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.949
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.948
|
|
|
|
growth of symbiont in host
|
GO:0044117 |
23 |
0.947
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
83 |
0.947
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.947
|
|
|
|
somatic cell dna recombination
|
GO:0016444 |
51 |
0.946
|
|
|
|
isotype switching
|
GO:0045190 |
36 |
0.944
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
52 |
0.943
|
|
|
|
negative regulation of interferon gamma production
|
GO:0032689 |
18 |
0.943
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.942
|
Mouse |
|
|
b cell activation
|
GO:0042113 |
161 |
0.941
|
|
|
|
positive regulation of fever generation by positive regulation of prostaglandin secretion
|
GO:0071812 |
2 |
0.941
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.939
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.937
|
|
|
|
regulation of immunoglobulin production
|
GO:0002637 |
42 |
0.937
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.936
|
|
|
|
positive regulation of immunoglobulin mediated immune response
|
GO:0002891 |
26 |
0.935
|
|
|
|
cd4 positive or cd8 positive alpha beta t cell lineage commitment
|
GO:0043369 |
8 |
0.934
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.931
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.925
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.924
|
|
|
|
cell surface pattern recognition receptor signaling pathway
|
GO:0002752 |
2 |
0.922
|
|
|
|
regulation of isotype switching
|
GO:0045191 |
22 |
0.922
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.921
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.919
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.917
|
Mouse |
|
|
regulation of immune complex clearance by monocytes and macrophages
|
GO:0090264 |
2 |
0.916
|
|
|
|
immunoglobulin secretion
|
GO:0048305 |
17 |
0.913
|
|
|
|
necroptotic process
|
GO:0070266 |
21 |
0.913
|
|
|
|
isotype switching to ige isotypes
|
GO:0048289 |
7 |
0.912
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.908
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.906
|
|
|
|
negative regulation of inflammatory response
|
GO:0050728 |
61 |
0.903
|
|
|
|
interferon beta biosynthetic process
|
GO:0045350 |
4 |
0.903
|
|
|
|
chronic inflammatory response to antigenic stimulus
|
GO:0002439 |
3 |
0.901
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.900
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.892
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.887
|
Mouse |
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.886
|
|
|
|
regulation of cytokine production involved in immune response
|
GO:0002718 |
26 |
0.885
|
|
|
|
positive regulation of interleukin 18 production
|
GO:0032741 |
2 |
0.885
|
|
|
|
keratinocyte migration
|
GO:0051546 |
3 |
0.882
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.880
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.879
|
|
|
|
regulation of isotype switching to ige isotypes
|
GO:0048293 |
7 |
0.879
|
|
|
|
regulation of acute inflammatory response
|
GO:0002673 |
27 |
0.873
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
49 |
0.873
|
Mouse |
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.870
|
Mouse |
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.868
|
|
|
|
positive regulation of chronic inflammatory response
|
GO:0002678 |
4 |
0.868
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.867
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.864
|
Mouse |
|
|
positive regulation of response to wounding
|
GO:1903036 |
66 |
0.864
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
36 |
0.863
|
Mouse |
|
|
interspecies interaction between organisms
|
GO:0044419 |
83 |
0.862
|
|
|
|
necroptotic signaling pathway
|
GO:0097527 |
3 |
0.861
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.861
|
|
|
|
interleukin 6 production
|
GO:0032635 |
58 |
0.860
|
Mouse |
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.859
|
|
|
|
t helper 1 cell lineage commitment
|
GO:0002296 |
2 |
0.858
|
|
|
|
nucleotide binding oligomerization domain containing signaling pathway
|
GO:0070423 |
6 |
0.854
|
|
|
|
myd88 dependent toll like receptor signaling pathway
|
GO:0002755 |
7 |
0.851
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.851
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.851
|
|
|
|
response to interleukin 15
|
GO:0070672 |
3 |
0.851
|
|
|
|
cytokine production involved in immune response
|
GO:0002367 |
34 |
0.847
|
|
|
|
regulation of fever generation by regulation of prostaglandin secretion
|
GO:0071810 |
2 |
0.846
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.845
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.844
|
|
|
|
cellular response to amino acid stimulus
|
GO:0071230 |
29 |
0.844
|
|
|
|
regulation of b cell mediated immunity
|
GO:0002712 |
37 |
0.841
|
|
|
|
modulation by symbiont of defense related host nitric oxide production
|
GO:0052163 |
1 |
0.835
|
|
|
|
progesterone metabolic process
|
GO:0042448 |
4 |
0.833
|
|
|
|
defense response to virus
|
GO:0051607 |
68 |
0.830
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.826
|
|
|
|
neutrophil apoptotic process
|
GO:0001781 |
3 |
0.825
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.819
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
49 |
0.818
|
|
|
|
response to host defenses
|
GO:0052200 |
3 |
0.817
|
|
|
|
natural killer cell mediated cytotoxicity
|
GO:0042267 |
29 |
0.816
|
|
|
|
negative regulation of growth of symbiont involved in interaction with host
|
GO:0044146 |
19 |
0.815
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.815
|
|
|
|
regulation of interleukin 6 biosynthetic process
|
GO:0045408 |
11 |
0.813
|
|
|
|
immunoglobulin production
|
GO:0002377 |
73 |
0.811
|
|
|
|
modification by symbiont of host morphology or physiology
|
GO:0044003 |
4 |
0.809
|
|
|
|
response to bacterial lipoprotein
|
GO:0032493 |
4 |
0.807
|
|
|
|
regulation of interleukin 6 production
|
GO:0032675 |
55 |
0.806
|
|
|
|
production of molecular mediator involved in inflammatory response
|
GO:0002532 |
21 |
0.797
|
|
|
|
t cell differentiation involved in immune response
|
GO:0002292 |
30 |
0.797
|
|
|
|
modification of morphology or physiology of other organism involved in symbiotic interaction
|
GO:0051817 |
16 |
0.794
|
|
|
|
response to defense related nitric oxide production by other organism involved in symbiotic interaction
|
GO:0052551 |
2 |
0.789
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.787
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
50 |
0.786
|
|
|
|
tyrosine phosphorylation of stat protein
|
GO:0007260 |
23 |
0.784
|
Mouse |
|
|
defense response to gram negative bacterium
|
GO:0050829 |
28 |
0.783
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.780
|
|
|
|
modulation by organism of defense related nitric oxide production in other organism involved in symbiotic interaction
|
GO:0052302 |
1 |
0.777
|
|
|
|
somatic diversification of immune receptors via germline recombination within a single locus
|
GO:0002562 |
51 |
0.771
|
|
|
|
negative regulation of interleukin 12 production
|
GO:0032695 |
10 |
0.770
|
|
|
|
drug catabolic process
|
GO:0042737 |
2 |
0.770
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.769
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
71 |
0.768
|
Mouse |
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.767
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.767
|
Mouse |
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
39 |
0.766
|
Mouse |
|
|
type 2 immune response
|
GO:0042092 |
23 |
0.760
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.759
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.759
|
Mouse |
|
|
positive regulation of nucleotide binding oligomerization domain containing 1 signaling pathway
|
GO:0070430 |
1 |
0.758
|
|
|
|
natural killer cell activation
|
GO:0030101 |
44 |
0.755
|
|
|
|
positive regulation of fever generation
|
GO:0031622 |
6 |
0.754
|
|
|
|
fever generation
|
GO:0001660 |
7 |
0.754
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.747
|
|
|
|
positive regulation of isotype switching
|
GO:0045830 |
15 |
0.746
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.745
|
|
|
|
mast cell proliferation
|
GO:0070662 |
4 |
0.745
|
|
|
|
negative regulation of interleukin 23 production
|
GO:0032707 |
1 |
0.742
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.742
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.738
|
Mouse |
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.738
|
Mouse |
|
|
alpha beta t cell activation involved in immune response
|
GO:0002287 |
31 |
0.736
|
|
|
|
immunoglobulin production involved in immunoglobulin mediated immune response
|
GO:0002381 |
43 |
0.734
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.733
|
|
|
|
acute inflammatory response
|
GO:0002526 |
41 |
0.733
|
|
|
|
positive regulation of interleukin 12 production
|
GO:0032735 |
21 |
0.732
|
|
|
|
t helper cell lineage commitment
|
GO:0002295 |
6 |
0.728
|
|
|
|
positive regulation of cytokine production involved in immune response
|
GO:0002720 |
19 |
0.725
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.722
|
|
|
|
eosinophil degranulation
|
GO:0043308 |
1 |
0.722
|
|
|
|
regulation of corticotropin releasing hormone secretion
|
GO:0043397 |
2 |
0.718
|
|
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
30 |
0.718
|
|
|
|
negative regulation of erk1 and erk2 cascade
|
GO:0070373 |
21 |
0.711
|
|
|
|
regulation of dna recombination
|
GO:0000018 |
34 |
0.711
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.707
|
Mouse |
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
65 |
0.707
|
|
|
|
positive regulation of tumor necrosis factor production
|
GO:0032760 |
30 |
0.704
|
|
|
|
regulation of t cell costimulation
|
GO:2000523 |
2 |
0.701
|
|
|
|
defense response to gram positive bacterium
|
GO:0050830 |
50 |
0.694
|
|
|
|
isotype switching to igg isotypes
|
GO:0048291 |
10 |
0.694
|
|
|
|
positive regulation of isotype switching to ige isotypes
|
GO:0048295 |
4 |
0.694
|
|
|
|
toll like receptor signaling pathway
|
GO:0002224 |
38 |
0.692
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
43 |
0.687
|
Mouse |
|
|
positive regulation by symbiont of host immune response
|
GO:0052556 |
1 |
0.685
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.684
|
Mouse |
|
|
alpha beta t cell differentiation involved in immune response
|
GO:0002293 |
30 |
0.684
|
|
|
|
alpha amino acid metabolic process
|
GO:1901605 |
59 |
0.679
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.679
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.675
|
|
|
|
modulation of growth of symbiont involved in interaction with host
|
GO:0044144 |
19 |
0.668
|
|
|
|
chemokine metabolic process
|
GO:0050755 |
10 |
0.660
|
|
|
|
inflammatory cell apoptotic process
|
GO:0006925 |
11 |
0.658
|
|
|
|
regulation of myoblast differentiation
|
GO:0045661 |
29 |
0.656
|
|
|
|
regulation of natural killer cell differentiation
|
GO:0032823 |
11 |
0.653
|
|
|
|
regulation of interleukin 18 production
|
GO:0032661 |
3 |
0.650
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.649
|
|
|
|
myeloid cell apoptotic process
|
GO:0033028 |
22 |
0.639
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.636
|
Mouse |
|
|
positive regulation of type i interferon production
|
GO:0032481 |
14 |
0.636
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.636
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.635
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.632
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.628
|
|
|
|
antibacterial peptide secretion
|
GO:0002779 |
1 |
0.626
|
|
|
|
interleukin 10 secretion
|
GO:0072608 |
4 |
0.625
|
|
|
|
regulation of alpha beta t cell proliferation
|
GO:0046640 |
18 |
0.625
|
|
|
|
positive regulation of translational initiation
|
GO:0045948 |
4 |
0.622
|
|
|
|
regulation of mast cell differentiation
|
GO:0060375 |
3 |
0.616
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
61 |
0.611
|
|
|
|
regulation of chronic inflammatory response
|
GO:0002676 |
7 |
0.611
|
|
|
|
response to defenses of other organism involved in symbiotic interaction
|
GO:0052173 |
3 |
0.608
|
|
|
|
regulation of natural killer cell proliferation
|
GO:0032817 |
2 |
0.607
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.604
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.602
|
|
|
|
tyrosine phosphorylation of stat3 protein
|
GO:0042503 |
12 |
0.599
|
Mouse |
|
|
regulation of immunoglobulin mediated immune response
|
GO:0002889 |
37 |
0.595
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.595
|
|
|
|
t helper cell differentiation
|
GO:0042093 |
28 |
0.592
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.592
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.592
|
|
|
|
positive regulation of glial cell proliferation
|
GO:0060252 |
4 |
0.592
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.589
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
65 |
0.587
|
Mouse |
|
|
jak stat cascade involved in growth hormone signaling pathway
|
GO:0060397 |
4 |
0.582
|
|
|
|
positive regulation of histone acetylation
|
GO:0035066 |
8 |
0.575
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.573
|
|
|
|
regulation of symbiosis encompassing mutualism through parasitism
|
GO:0043903 |
52 |
0.573
|
|
|
|
response to interleukin 1
|
GO:0070555 |
11 |
0.572
|
|
|
|
positive regulation of lymphocyte differentiation
|
GO:0045621 |
61 |
0.571
|
|
|
|
negative regulation of t cell cytokine production
|
GO:0002725 |
1 |
0.568
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.567
|
|
|
|
positive regulation of hematopoietic stem cell migration
|
GO:2000473 |
1 |
0.566
|
|
|
|
regulation of type 2 immune response
|
GO:0002828 |
18 |
0.565
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.561
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.553
|
Mouse |
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.552
|
|
|
|
mhc class ii biosynthetic process
|
GO:0045342 |
8 |
0.552
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.551
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.548
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.543
|
|
|
|
somatic diversification of immunoglobulins
|
GO:0016445 |
43 |
0.540
|
|
|
|
growth of symbiont involved in interaction with host
|
GO:0044116 |
23 |
0.539
|
|
|
|
negative regulation of adaptive immune response
|
GO:0002820 |
25 |
0.538
|
|
|
|
response to oxygen levels
|
GO:0070482 |
62 |
0.533
|
|
|
|
immune complex clearance
|
GO:0002434 |
2 |
0.533
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.533
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.530
|
|
|
|
regulation of syncytium formation by plasma membrane fusion
|
GO:0060142 |
23 |
0.529
|
|
|
|
positive regulation of immunoglobulin secretion
|
GO:0051024 |
7 |
0.526
|
|
|
|
negative regulation of chronic inflammatory response
|
GO:0002677 |
3 |
0.521
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.517
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
144 |
0.516
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.515
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.511
|
|
|
|
growth involved in symbiotic interaction
|
GO:0044110 |
23 |
0.509
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.508
|
|
|
|
antibacterial peptide biosynthetic process
|
GO:0002780 |
2 |
0.506
|
|
|
|
nucleotide binding oligomerization domain containing 2 signaling pathway
|
GO:0070431 |
6 |
0.504
|
|
|
|
positive regulation of tyrosine phosphorylation of stat protein
|
GO:0042531 |
15 |
0.504
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.499
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.498
|
|
|
|
detection of molecule of bacterial origin
|
GO:0032490 |
2 |
0.498
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.497
|
|
|
|
regulation of lipopolysaccharide mediated signaling pathway
|
GO:0031664 |
9 |
0.496
|
|
|
|
mammary gland epithelial cell proliferation
|
GO:0033598 |
24 |
0.495
|
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
52 |
0.494
|
|
|
|
induction by symbiont of host immune response
|
GO:0052559 |
1 |
0.492
|
|
|
|
regulation of nucleotide binding oligomerization domain containing 2 signaling pathway
|
GO:0070432 |
3 |
0.489
|
|
|
|
cd4 positive alpha beta t cell lineage commitment
|
GO:0043373 |
6 |
0.488
|
|
|
|
chemokine biosynthetic process
|
GO:0042033 |
8 |
0.488
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.487
|
Mouse |
|
|
alpha beta t cell lineage commitment
|
GO:0002363 |
7 |
0.484
|
|
|
|
cellular response to bacterial lipoprotein
|
GO:0071220 |
3 |
0.484
|
|
|
|
eosinophil activation
|
GO:0043307 |
1 |
0.481
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.477
|
|
|
|
positive regulation of immunological synapse formation
|
GO:2000522 |
1 |
0.477
|
|
|
|
negative regulation of interleukin 5 production
|
GO:0032714 |
4 |
0.477
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.475
|
|
|
|
b cell mediated immunity
|
GO:0019724 |
71 |
0.472
|
|
|
|
positive regulation of interleukin 6 production
|
GO:0032755 |
37 |
0.471
|
|
|
|
regulation of nucleotide binding oligomerization domain containing signaling pathway
|
GO:0070424 |
3 |
0.461
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.461
|
|
|
|
negative regulation of interleukin 5 secretion
|
GO:2000663 |
1 |
0.460
|
|
|
|
response to host
|
GO:0075136 |
3 |
0.459
|
|
|
|
placenta development
|
GO:0001890 |
140 |
0.457
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.455
|
Mouse |
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.455
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.455
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.454
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.449
|
|
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
70 |
0.447
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.444
|
|
|
|
corticotropin releasing hormone secretion
|
GO:0043396 |
2 |
0.441
|
|
|
|
regulation of tumor necrosis factor biosynthetic process
|
GO:0042534 |
10 |
0.440
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.437
|
|
|
|
regulation of jak stat cascade
|
GO:0046425 |
34 |
0.437
|
Mouse |
|
|
branching involved in salivary gland morphogenesis
|
GO:0060445 |
26 |
0.437
|
|
|
|
dephosphorylation
|
GO:0016311 |
129 |
0.434
|
|
|
|
positive regulation of activation of membrane attack complex
|
GO:0001970 |
2 |
0.432
|
|
|
|
exogenous drug catabolic process
|
GO:0042738 |
1 |
0.430
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.427
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.425
|
Mouse |
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.423
|
|
|
|
positive regulation of immunoglobulin production
|
GO:0002639 |
28 |
0.422
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.419
|
|
|
|
positive regulation of dna recombination
|
GO:0045911 |
17 |
0.416
|
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
77 |
0.413
|
|
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
39 |
0.412
|
|
|
|
regulation of b cell proliferation
|
GO:0030888 |
39 |
0.412
|
|
|
|
acute phase response
|
GO:0006953 |
10 |
0.410
|
|
|
|
positive regulation of jak stat cascade
|
GO:0046427 |
22 |
0.407
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
11 |
0.407
|
|
|
|
regulation of histone acetylation
|
GO:0035065 |
19 |
0.407
|
|
|
|
t cell selection
|
GO:0045058 |
34 |
0.400
|
|
|
|
modulation by symbiont of host immune response
|
GO:0052553 |
1 |
0.398
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
42 |
0.396
|
|
|
|
organ or tissue specific immune response
|
GO:0002251 |
13 |
0.396
|
|
|
|
positive regulation of lipopolysaccharide mediated signaling pathway
|
GO:0031666 |
5 |
0.391
|
|
|
|
salivary gland development
|
GO:0007431 |
37 |
0.390
|
|
|
|
negative regulation of chemokine biosynthetic process
|
GO:0045079 |
2 |
0.387
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
79 |
0.383
|
Mouse |
|
|
regulation of chemokine production
|
GO:0032642 |
30 |
0.378
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.378
|
|
|
|
leukocyte homeostasis
|
GO:0001776 |
79 |
0.377
|
|
|
|
modulation by organism of immune response of other organism involved in symbiotic interaction
|
GO:0052552 |
1 |
0.376
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.372
|
|
|
|
regulation of tyrosine phosphorylation of stat protein
|
GO:0042509 |
20 |
0.371
|
Mouse |
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.368
|
|
|
|
positive regulation of b cell proliferation
|
GO:0030890 |
24 |
0.365
|
|
|
|
natural killer cell mediated immunity
|
GO:0002228 |
29 |
0.363
|
|
|
|
protein oligomerization
|
GO:0051259 |
67 |
0.363
|
|
|
|
heat generation
|
GO:0031649 |
13 |
0.362
|
|
|
|
positive regulation by organism of immune response of other organism involved in symbiotic interaction
|
GO:0052555 |
1 |
0.361
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.360
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.357
|
|
|
|
defense response to protozoan
|
GO:0042832 |
25 |
0.356
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.352
|
Mouse |
|
|
cellular response to bacterial lipopeptide
|
GO:0071221 |
3 |
0.350
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.348
|
|
|
|
positive regulation of leukocyte mediated cytotoxicity
|
GO:0001912 |
31 |
0.346
|
|
|
|
negative regulation of macrophage apoptotic process
|
GO:2000110 |
3 |
0.343
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.342
|
Mouse |
|
|
positive regulation of histone modification
|
GO:0031058 |
28 |
0.341
|
|
|
|
positive regulation of monocyte chemotaxis
|
GO:0090026 |
2 |
0.341
|
|
|
|
positive regulation of chemokine production
|
GO:0032722 |
22 |
0.340
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
44 |
0.340
|
Mouse |
|
|
regulation of mast cell proliferation
|
GO:0070666 |
4 |
0.339
|
|
|
|
positive regulation of cd8 positive alpha beta t cell extravasation
|
GO:2000451 |
2 |
0.334
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.334
|
|
|
|
eosinophil activation involved in immune response
|
GO:0002278 |
1 |
0.333
|
|
|
|
positive regulation of lymphocyte mediated immunity
|
GO:0002708 |
62 |
0.332
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.329
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.328
|
|
|
|
response to iron ion
|
GO:0010039 |
4 |
0.328
|
|
|
|
activation of mapk activity involved in innate immune response
|
GO:0035419 |
2 |
0.322
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.319
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.317
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
81 |
0.317
|
|
|
|
regulation of chemokine biosynthetic process
|
GO:0045073 |
8 |
0.314
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.314
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.313
|
|
|
|
muscle cell proliferation
|
GO:0033002 |
52 |
0.312
|
|
|
|
natural killer cell proliferation
|
GO:0001787 |
3 |
0.311
|
|
|
|
b cell proliferation
|
GO:0042100 |
53 |
0.309
|
|
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.308
|
|
|
|
positive regulation of chemokine biosynthetic process
|
GO:0045080 |
6 |
0.307
|
|
|
|
lymphocyte apoptotic process
|
GO:0070227 |
54 |
0.306
|
|
|
|
positive regulation of tyrosine phosphorylation of stat1 protein
|
GO:0042511 |
1 |
0.306
|
|
|
|
t cell activation involved in immune response
|
GO:0002286 |
43 |
0.305
|
|
|
|
regulation of defense response to bacterium
|
GO:1900424 |
3 |
0.304
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.303
|
|
|
|
drug metabolic process
|
GO:0017144 |
4 |
0.302
|
|
|
|
response to hypoxia
|
GO:0001666 |
58 |
0.299
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.299
|
|
|
|
positive regulation by organism of defense related nitric oxide production in other organism involved in symbiotic interaction
|
GO:0052345 |
1 |
0.296
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.295
|
|
|
|
nucleotide binding domain leucine rich repeat containing receptor signaling pathway
|
GO:0035872 |
6 |
0.294
|
|
|
|
interleukin 27 mediated signaling pathway
|
GO:0070106 |
1 |
0.293
|
|
|
|
modification of morphology or physiology of other organism
|
GO:0035821 |
18 |
0.289
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.284
|
|
|
|
regulation of myotube differentiation
|
GO:0010830 |
62 |
0.282
|
|
|
|
humoral immune response
|
GO:0006959 |
57 |
0.282
|
|
|
|
positive regulation of chemotaxis
|
GO:0050921 |
38 |
0.281
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.279
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.278
|
|
|
|
antibiotic transport
|
GO:0042891 |
1 |
0.277
|
|
|
|
positive regulation of t cell costimulation
|
GO:2000525 |
2 |
0.275
|
|
|
|
mammary gland lobule development
|
GO:0061377 |
22 |
0.275
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.274
|
|
|
|
extrinsic apoptotic signaling pathway via death domain receptors
|
GO:0008625 |
34 |
0.274
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
74 |
0.272
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.271
|
|
|
|
glucagon secretion
|
GO:0070091 |
3 |
0.271
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.264
|
|
|
|
positive regulation of t cell receptor signaling pathway
|
GO:0050862 |
4 |
0.264
|
|
|
|
modulation by symbiont of host defense response
|
GO:0052031 |
1 |
0.257
|
|
|
|
positive regulation of inflammatory response
|
GO:0050729 |
47 |
0.255
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.255
|
|
|
|
smad protein complex assembly
|
GO:0007183 |
1 |
0.254
|
|
|
|
positive regulation of acute inflammatory response
|
GO:0002675 |
16 |
0.254
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.253
|
|
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.252
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.251
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
121 |
0.246
|
|
|
|
negative regulation of lymphocyte proliferation
|
GO:0050672 |
45 |
0.246
|
|
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.245
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.244
|
|
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.243
|
|
|
|
positive regulation of muscle cell differentiation
|
GO:0051149 |
39 |
0.242
|
|
|
|
t helper 1 type immune response
|
GO:0042088 |
25 |
0.242
|
|
|
|
regulation of isotype switching to igg isotypes
|
GO:0048302 |
10 |
0.240
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
62 |
0.240
|
Mouse |
|
|
glutamine family amino acid catabolic process
|
GO:0009065 |
5 |
0.239
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.239
|
|
|
|
alpha amino acid catabolic process
|
GO:1901606 |
18 |
0.239
|
|
|
|
negative regulation of type 2 immune response
|
GO:0002829 |
8 |
0.238
|
|
|
|
cell cell recognition
|
GO:0009988 |
44 |
0.237
|
|
|
|
inflammatory response to wounding
|
GO:0090594 |
4 |
0.235
|
|
|
|
response to granulocyte macrophage colony stimulating factor
|
GO:0097012 |
3 |
0.235
|
|
|
|
positive regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903557 |
31 |
0.235
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.234
|
|
|
|
branching involved in mammary gland duct morphogenesis
|
GO:0060444 |
27 |
0.233
|
|
|
|
response to interferon gamma
|
GO:0034341 |
34 |
0.232
|
|
|
|
response to amino acid
|
GO:0043200 |
37 |
0.231
|
|
|
|
regulation of peptidyl serine phosphorylation
|
GO:0033135 |
39 |
0.228
|
|
|
|
cytoplasmic pattern recognition receptor signaling pathway
|
GO:0002753 |
10 |
0.226
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.226
|
|
|
|
zymogen activation
|
GO:0031638 |
41 |
0.224
|
|
|
|
regulation of cd4 positive alpha beta t cell differentiation
|
GO:0043370 |
21 |
0.222
|
|
|
|
regulation of interferon beta biosynthetic process
|
GO:0045357 |
4 |
0.221
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
38 |
0.220
|
|
|
|
induction by organism of defense related nitric oxide production in other organism involved in symbiotic interaction
|
GO:0052263 |
1 |
0.220
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.218
|
|
|
|
response to interleukin 4
|
GO:0070670 |
23 |
0.218
|
|
|
|
cellular response to interferon gamma
|
GO:0071346 |
25 |
0.217
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.215
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.214
|
Mouse |
|
|
histone acetylation
|
GO:0016573 |
41 |
0.210
|
|
|
|
granulocyte migration
|
GO:0097530 |
43 |
0.210
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.208
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
97 |
0.208
|
|
|
|
tyrosine phosphorylation of stat1 protein
|
GO:0042508 |
3 |
0.207
|
|
|
|
positive regulation of interferon alpha production
|
GO:0032727 |
4 |
0.206
|
|
|
|
response to host immune response
|
GO:0052572 |
3 |
0.206
|
|
|
|
positive regulation of natural killer cell mediated immunity
|
GO:0002717 |
16 |
0.205
|
|
|
|
activation induced cell death of t cells
|
GO:0006924 |
10 |
0.205
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.205
|
|
|
|
regulation of immunoglobulin secretion
|
GO:0051023 |
12 |
0.204
|
|
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
81 |
0.204
|
|
|
|
regulation of myeloid dendritic cell activation
|
GO:0030885 |
5 |
0.203
|
|
|
|
negative regulation of glycolytic process
|
GO:0045820 |
4 |
0.203
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.202
|
|
|
|
positive regulation of protein import into nucleus
|
GO:0042307 |
26 |
0.202
|
|
|
|
regulation of dendritic cell chemotaxis
|
GO:2000508 |
1 |
0.202
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.201
|
|
|
|
positive regulation of gamma delta t cell differentiation
|
GO:0045588 |
6 |
0.199
|
|
|
|
vascular endothelial growth factor production
|
GO:0010573 |
13 |
0.199
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.198
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.197
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.197
|
|
|
|
necrotic cell death
|
GO:0070265 |
30 |
0.197
|
|
|
|
regulation of toll like receptor 2 signaling pathway
|
GO:0034135 |
3 |
0.197
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.196
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.196
|
|
|
|
negative regulation of chemokine production
|
GO:0032682 |
4 |
0.195
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.195
|
Mouse |
|
|
regulation of nucleotide binding oligomerization domain containing 1 signaling pathway
|
GO:0070428 |
3 |
0.195
|
|
|
|
regulation of vitamin metabolic process
|
GO:0030656 |
3 |
0.195
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.194
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.194
|
|
|
|
regulation of osteoclast differentiation
|
GO:0045670 |
36 |
0.193
|
|
|
|
regulation of natural killer cell mediated immunity
|
GO:0002715 |
19 |
0.192
|
|
|
|
positive regulation of synaptic plasticity
|
GO:0031915 |
4 |
0.190
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.190
|
|
|
|
positive regulation of antibacterial peptide biosynthetic process
|
GO:0006963 |
1 |
0.188
|
|
|
|
positive regulation of chronic inflammatory response to antigenic stimulus
|
GO:0002876 |
2 |
0.188
|
|
|
|
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002823 |
23 |
0.186
|
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.183
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
74 |
0.183
|
|
