Mus musculus

159 known processes

Il12b

interleukin 12b

(Aliases: p40,Il12p40,Il-12p40,Il-12b)

Il12b biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cytokine production GO:0001816 319 0.905
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.727
defense response to other organism GO:0098542 197 0.696
t cell proliferation GO:0042098 120 0.647
regulation of t cell proliferation GO:0042129 92 0.615
positive regulation of cytokine production GO:0001819 174 0.610
regulation of cytokine production GO:0001817 266 0.593
cellular amine metabolic process GO:0044106 44 0.567
myeloid leukocyte differentiation GO:0002573 119 0.551
leukocyte proliferation GO:0070661 172 0.545
regulation of leukocyte mediated immunity GO:0002703 104 0.538
lymphocyte mediated immunity GO:0002449 139 0.532
positive regulation of lymphocyte activation GO:0051251 140 0.480
immune effector process GO:0002252 321 0.478
cellular amino acid metabolic process GO:0006520 103 0.455
regulation of defense response GO:0031347 233 0.405
cellular response to growth factor stimulus GO:0071363 197 0.403
positive regulation of t cell proliferation GO:0042102 52 0.385
defense response to virus GO:0051607 68 0.377
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.371
myeloid cell differentiation GO:0030099 233 0.367
regulation of leukocyte differentiation GO:1902105 159 0.366
regulation of lymphocyte activation GO:0051249 240 0.363
positive regulation of lymphocyte proliferation GO:0050671 70 0.362
acid secretion GO:0046717 33 0.352
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.351
regulation of lymphocyte proliferation GO:0050670 117 0.351
positive regulation of leukocyte mediated immunity GO:0002705 70 0.340
leukocyte differentiation GO:0002521 342 0.338
amine metabolic process GO:0009308 45 0.328
positive regulation of cell motility GO:2000147 116 0.322
regulation of cell activation GO:0050865 289 0.319
response to organic cyclic compound GO:0014070 198 0.312
tumor necrosis factor production GO:0032640 50 0.309
positive regulation of cell migration GO:0030335 109 0.304
positive regulation of cellular amine metabolic process GO:0033240 5 0.302
cellular ketone metabolic process GO:0042180 84 0.298
regulation of cellular amine metabolic process GO:0033238 20 0.293
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.264
t cell activation GO:0042110 289 0.260
positive regulation of tumor necrosis factor production GO:0032760 30 0.257
cation transport GO:0006812 399 0.247
negative regulation of cytokine production GO:0001818 84 0.247
alpha beta t cell activation GO:0046631 91 0.245
positive regulation of leukocyte proliferation GO:0070665 73 0.229
cd4 positive alpha beta t cell activation GO:0035710 45 0.228
blood vessel morphogenesis GO:0048514 285 0.225
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.224
response to molecule of bacterial origin GO:0002237 143 0.224
positive regulation of immune effector process GO:0002699 107 0.220
regulation of t cell activation GO:0050863 170 0.216
regulation of myeloid cell differentiation GO:0045637 96 0.215
alpha beta t cell differentiation GO:0046632 69 0.206
metal ion homeostasis GO:0055065 189 0.202
defense response to bacterium GO:0042742 119 0.202
regulation of cell motility GO:2000145 236 0.201
positive regulation of t cell activation GO:0050870 101 0.201
positive regulation of secretion GO:0051047 130 0.197
temperature homeostasis GO:0001659 26 0.192
regulation of interferon gamma production GO:0032649 57 0.184
positive regulation of cell activation GO:0050867 158 0.184
anion transport GO:0006820 177 0.183
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.181
regulation of system process GO:0044057 200 0.179
innate immune response GO:0045087 157 0.178
t cell mediated immunity GO:0002456 50 0.177
regulation of cellular ketone metabolic process GO:0010565 66 0.174
phenol containing compound metabolic process GO:0018958 60 0.172
gland development GO:0048732 330 0.171
negative regulation of t cell proliferation GO:0042130 38 0.168
regulation of blood circulation GO:1903522 93 0.167
regulation of establishment of protein localization GO:0070201 181 0.166
cell activation involved in immune response GO:0002263 126 0.165
stem cell differentiation GO:0048863 268 0.163
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.160
regulation of ion transport GO:0043269 215 0.160
regulation of secretion by cell GO:1903530 249 0.155
cell killing GO:0001906 67 0.154
positive regulation of interferon gamma production GO:0032729 39 0.153
myeloid leukocyte migration GO:0097529 57 0.153
multicellular organismal homeostasis GO:0048871 164 0.148
regulation of cellular amino acid metabolic process GO:0006521 5 0.144
g protein coupled receptor signaling pathway GO:0007186 243 0.143
defense response to gram negative bacterium GO:0050829 28 0.143
developmental maturation GO:0021700 193 0.142
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.138
extracellular matrix organization GO:0030198 147 0.135
regulation of protein transport GO:0051223 163 0.135
regulation of homeostatic process GO:0032844 182 0.134
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.134
alpha beta t cell proliferation GO:0046633 21 0.133
kidney development GO:0001822 213 0.131
inflammatory response GO:0006954 244 0.129
regulation of tumor necrosis factor production GO:0032680 49 0.129
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.127
positive regulation of adaptive immune response GO:0002821 61 0.126
organic anion transport GO:0015711 137 0.125
negative regulation of t cell activation GO:0050868 65 0.124
anatomical structure homeostasis GO:0060249 145 0.123
regulation of cell migration GO:0030334 219 0.122
positive regulation of cytokine secretion GO:0050715 41 0.121
extracellular structure organization GO:0043062 148 0.121
leukocyte mediated immunity GO:0002443 174 0.121
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.119
chemotaxis GO:0006935 247 0.118
positive regulation of leukocyte differentiation GO:1902107 86 0.117
positive regulation of t cell mediated cytotoxicity GO:0001916 15 0.114
response to growth factor GO:0070848 198 0.113
natural killer cell activation GO:0030101 44 0.113
regulation of lymphocyte mediated immunity GO:0002706 84 0.112
peptidyl tyrosine phosphorylation GO:0018108 143 0.112
circulatory system process GO:0003013 197 0.110
homeostasis of number of cells GO:0048872 210 0.108
negative regulation of defense response GO:0031348 77 0.108
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.106
positive regulation of homeostatic process GO:0032846 64 0.106
osteoclast differentiation GO:0030316 62 0.106
regulation of myeloid leukocyte differentiation GO:0002761 58 0.104
negative regulation of immune system process GO:0002683 209 0.103
response to lipopolysaccharide GO:0032496 128 0.103
positive regulation of secretion by cell GO:1903532 114 0.103
organic hydroxy compound transport GO:0015850 93 0.102
negative regulation of cell proliferation GO:0008285 296 0.102
leukocyte activation involved in immune response GO:0002366 126 0.101
oocyte axis specification GO:0007309 2 0.100
neutrophil chemotaxis GO:0030593 36 0.100
leukocyte migration GO:0050900 124 0.099
regulation of cell killing GO:0031341 40 0.098
t helper 17 cell differentiation GO:0072539 7 0.098
carbohydrate derivative biosynthetic process GO:1901137 183 0.098
branching morphogenesis of an epithelial tube GO:0048754 159 0.098
organic hydroxy compound metabolic process GO:1901615 203 0.097
cellular calcium ion homeostasis GO:0006874 119 0.097
positive regulation of defense response GO:0031349 124 0.095
odontogenesis GO:0042476 78 0.094
response to transforming growth factor beta GO:0071559 88 0.093
positive regulation of myeloid leukocyte differentiation GO:0002763 26 0.092
gastrin induced gastric acid secretion GO:0001698 1 0.092
interferon gamma production GO:0032609 67 0.091
regulation of granulocyte chemotaxis GO:0071622 17 0.091
associative learning GO:0008306 61 0.090
regulation of osteoclast differentiation GO:0045670 36 0.089
negative regulation of interleukin 10 secretion GO:2001180 2 0.089
protein catabolic process GO:0030163 221 0.088
leukocyte mediated cytotoxicity GO:0001909 62 0.087
leukocyte chemotaxis GO:0030595 69 0.087
negative regulation of secretion by cell GO:1903531 54 0.085
regulation of endocytosis GO:0030100 69 0.085
skeletal system development GO:0001501 356 0.085
regulation of protein localization GO:0032880 231 0.084
jak stat cascade GO:0007259 42 0.084
positive regulation of protein transport GO:0051222 93 0.083
heat generation GO:0031649 13 0.083
regulation of hormone levels GO:0010817 211 0.083
peptidyl amino acid modification GO:0018193 336 0.082
monocarboxylic acid transport GO:0015718 44 0.081
regulation of reactive oxygen species metabolic process GO:2000377 40 0.081
myeloid leukocyte activation GO:0002274 83 0.080
response to alcohol GO:0097305 48 0.080
cellular metal ion homeostasis GO:0006875 151 0.080
cytokine secretion GO:0050663 72 0.079
regulation of secretion GO:0051046 274 0.078
regulation of t cell differentiation GO:0045580 83 0.078
organic acid transport GO:0015849 101 0.078
myoblast differentiation GO:0045445 52 0.078
regulation of b cell proliferation GO:0030888 39 0.077
t cell lineage commitment GO:0002360 13 0.077
regulation of monocyte chemotaxis GO:0090025 3 0.077
action potential GO:0001508 78 0.074
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.073
astrocyte fate commitment GO:0060018 4 0.073
locomotory behavior GO:0007626 195 0.073
lymphocyte differentiation GO:0030098 242 0.073
syncytium formation by plasma membrane fusion GO:0000768 42 0.073
regulation of t cell mediated immunity GO:0002709 34 0.072
protein secretion GO:0009306 111 0.072
extrinsic apoptotic signaling pathway GO:0097191 126 0.071
ossification GO:0001503 216 0.070
reactive oxygen species metabolic process GO:0072593 84 0.070
negative regulation of growth GO:0045926 99 0.070
positive regulation of interleukin 12 production GO:0032735 21 0.069
positive regulation of cell death GO:0010942 224 0.069
cytoplasmic transport GO:0016482 234 0.069
calcium ion homeostasis GO:0055074 127 0.069
carboxylic acid transport GO:0046942 100 0.069
positive regulation of t cell differentiation GO:0045582 52 0.069
regulation of organic acid transport GO:0032890 16 0.068
t helper cell differentiation GO:0042093 28 0.068
regulation of granulocyte macrophage colony stimulating factor production GO:0032645 3 0.067
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 28 0.067
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.067
response to organonitrogen compound GO:0010243 246 0.067
interleukin 12 production GO:0032615 32 0.066
cellular chemical homeostasis GO:0055082 215 0.066
immune response activating signal transduction GO:0002757 116 0.066
positive regulation of nervous system development GO:0051962 221 0.066
morphogenesis of a branching epithelium GO:0061138 193 0.065
urogenital system development GO:0001655 261 0.065
positive regulation of lymphocyte differentiation GO:0045621 61 0.064
placenta development GO:0001890 140 0.064
cell fate commitment GO:0045165 210 0.063
negative regulation of protein metabolic process GO:0051248 282 0.063
epithelial tube morphogenesis GO:0060562 303 0.063
endocytosis GO:0006897 168 0.062
catecholamine metabolic process GO:0006584 30 0.062
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.062
negative regulation of leukocyte proliferation GO:0070664 46 0.062
granulocyte migration GO:0097530 43 0.062
amino acid transport GO:0006865 61 0.062
peptidyl tyrosine modification GO:0018212 145 0.061
regulation of corticotropin releasing hormone secretion GO:0043397 2 0.061
neuromuscular process GO:0050905 99 0.061
regulation of chemotaxis GO:0050920 53 0.061
alpha beta t cell activation involved in immune response GO:0002287 31 0.061
negative regulation of homeostatic process GO:0032845 71 0.061
second messenger mediated signaling GO:0019932 73 0.060
cellular homeostasis GO:0019725 240 0.060
cellular response to molecule of bacterial origin GO:0071219 83 0.060
regulation of ion homeostasis GO:2000021 64 0.060
regulation of interleukin 6 production GO:0032675 55 0.060
positive regulation of granulocyte macrophage colony stimulating factor production GO:0032725 3 0.059
mating GO:0007618 27 0.059
regulation of mapk cascade GO:0043408 248 0.059
i kappab kinase nf kappab signaling GO:0007249 85 0.059
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 31 0.059
positive regulation of innate immune response GO:0045089 80 0.058
tissue homeostasis GO:0001894 115 0.058
hormone secretion GO:0046879 128 0.058
adaptive immune response GO:0002250 155 0.057
t cell activation involved in immune response GO:0002286 43 0.057
fat cell differentiation GO:0045444 160 0.057
vasodilation by norepinephrine epinephrine involved in regulation of systemic arterial blood pressure GO:0002025 3 0.056
negative regulation of lymphocyte proliferation GO:0050672 45 0.056
cell chemotaxis GO:0060326 81 0.056
t helper 17 cell lineage commitment GO:0072540 4 0.055
histamine induced gastric acid secretion GO:0001697 1 0.055
regulation of leukocyte proliferation GO:0070663 121 0.055
regulation of blood vessel size GO:0050880 56 0.055
regulation of muscle system process GO:0090257 80 0.055
corticotropin releasing hormone secretion GO:0043396 2 0.054
regulation of cytokine secretion GO:0050707 61 0.054
regulation of cellular component biogenesis GO:0044087 181 0.054
tyrosine phosphorylation of stat protein GO:0007260 23 0.054
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.054
tissue remodeling GO:0048771 102 0.053
brown fat cell differentiation GO:0050873 36 0.053
membrane organization GO:0061024 245 0.053
positive regulation of endocytosis GO:0045807 42 0.053
g protein coupled receptor internalization GO:0002031 3 0.053
cation homeostasis GO:0055080 212 0.053
positive regulation of heart rate by epinephrine norepinephrine GO:0001996 4 0.052
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.052
negative regulation of serotonin secretion GO:0014063 2 0.052
phospholipase c activating serotonin receptor signaling pathway GO:0007208 1 0.052
cytosolic calcium ion homeostasis GO:0051480 70 0.052
sensitization GO:0046960 2 0.051
positive regulation of chemotaxis GO:0050921 38 0.051
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.051
respiratory tube development GO:0030323 167 0.051
positive regulation of protein secretion GO:0050714 52 0.051
regulation of alpha beta t cell activation GO:0046634 53 0.051
regulation of innate immune response GO:0045088 91 0.051
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.051
pattern recognition receptor signaling pathway GO:0002221 47 0.051
endochondral bone morphogenesis GO:0060350 50 0.050
lipid transport GO:0006869 98 0.050
positive regulation of glycolytic process GO:0045821 4 0.050
regulation of organelle organization GO:0033043 289 0.050
regulation of serotonin secretion GO:0014062 3 0.050
alpha beta t cell differentiation involved in immune response GO:0002293 30 0.049
positive regulation of myeloid cell differentiation GO:0045639 43 0.049
regulation of membrane potential GO:0042391 192 0.049
positive regulation of the force of heart contraction by epinephrine norepinephrine GO:0001997 3 0.049
negative regulation of cellular protein metabolic process GO:0032269 247 0.049
sequestering of metal ion GO:0051238 19 0.049
cytokine metabolic process GO:0042107 71 0.048
nucleotide metabolic process GO:0009117 332 0.048
maintenance of location GO:0051235 89 0.048
regulation of alpha beta t cell proliferation GO:0046640 18 0.048
detection of yeast GO:0001879 2 0.048
divalent inorganic cation transport GO:0072511 178 0.048
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.048
amide transport GO:0042886 138 0.048
sequestering of calcium ion GO:0051208 18 0.048
mesenchymal cell development GO:0014031 93 0.047
negative regulation of phosphate metabolic process GO:0045936 184 0.047
cellular response to abiotic stimulus GO:0071214 56 0.046
blood circulation GO:0008015 195 0.046
positive regulation of the force of heart contraction by chemical signal GO:0003099 3 0.046
muscle cell differentiation GO:0042692 261 0.046
regulation of inflammatory response GO:0050727 147 0.046
reactive nitrogen species metabolic process GO:2001057 0 0.046
interleukin 6 production GO:0032635 58 0.045
response to extracellular stimulus GO:0009991 127 0.045
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.045
nk t cell proliferation GO:0001866 2 0.045
tyrosine phosphorylation of stat5 protein GO:0042506 9 0.045
regulation of cd4 positive alpha beta t cell activation GO:2000514 24 0.044
cellular response to dna damage stimulus GO:0006974 207 0.044
regulation of cytokine biosynthetic process GO:0042035 59 0.044
granulocyte macrophage colony stimulating factor production GO:0032604 3 0.044
glycosyl compound metabolic process GO:1901657 246 0.044
positive regulation of alpha beta t cell activation GO:0046635 39 0.044
erk1 and erk2 cascade GO:0070371 77 0.044
regulation of vasculature development GO:1901342 88 0.044
myeloid dendritic cell differentiation GO:0043011 16 0.043
regulation of t cell mediated cytotoxicity GO:0001914 18 0.043
regulation of interleukin 10 secretion GO:2001179 4 0.043
positive regulation of neutrophil chemotaxis GO:0090023 12 0.043
granulocyte chemotaxis GO:0071621 39 0.042
defense response to gram positive bacterium GO:0050830 50 0.042
monovalent inorganic cation homeostasis GO:0055067 33 0.042
protein modification by small protein conjugation GO:0032446 187 0.042
connective tissue development GO:0061448 179 0.042
positive regulation of alpha beta t cell differentiation GO:0046638 28 0.042
positive regulation of programmed cell death GO:0043068 218 0.041
metanephros development GO:0001656 79 0.041
regulation of striated muscle cell differentiation GO:0051153 81 0.041
lipid localization GO:0010876 126 0.041
positive regulation of neutrophil migration GO:1902624 12 0.041
regulation of syncytium formation by plasma membrane fusion GO:0060142 23 0.041
rhythmic process GO:0048511 174 0.041
regulation of neutrophil migration GO:1902622 14 0.040
pallium development GO:0021543 120 0.040
regulation of hormone secretion GO:0046883 88 0.040
interleukin 10 secretion GO:0072608 4 0.040
synaptic transmission GO:0007268 329 0.039
positive regulation of osteoclast differentiation GO:0045672 15 0.039
serotonin receptor signaling pathway GO:0007210 8 0.039
nucleobase containing small molecule metabolic process GO:0055086 352 0.039
cognition GO:0050890 149 0.039
axonogenesis GO:0007409 274 0.039
cytokine biosynthetic process GO:0042089 68 0.039
regulation of vesicle mediated transport GO:0060627 139 0.039
vasoconstriction GO:0042310 27 0.039
segmentation GO:0035282 93 0.038
regulation of interleukin 12 production GO:0032655 30 0.038
nucleotide biosynthetic process GO:0009165 78 0.038
digestive tract morphogenesis GO:0048546 147 0.038
protein kinase c activating g protein coupled receptor signaling pathway GO:0007205 4 0.038
purine ribonucleoside metabolic process GO:0046128 241 0.038
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 30 0.037
digestive system development GO:0055123 200 0.037
positive regulation of interleukin 6 production GO:0032755 37 0.037
calcium ion transport GO:0006816 159 0.037
intracellular protein transport GO:0006886 204 0.037
hematopoietic progenitor cell differentiation GO:0002244 143 0.037
oocyte differentiation GO:0009994 35 0.037
camp biosynthetic process GO:0006171 31 0.037
wound healing GO:0042060 157 0.037
reactive oxygen species biosynthetic process GO:1903409 8 0.036
odontogenesis of dentin containing tooth GO:0042475 66 0.036
production of molecular mediator of immune response GO:0002440 103 0.036
circadian rhythm GO:0007623 114 0.036
transmission of nerve impulse GO:0019226 76 0.036
syncytium formation GO:0006949 43 0.036
positive regulation of lipid transport GO:0032370 22 0.036
bone resorption GO:0045453 38 0.036
response to acid chemical GO:0001101 111 0.036
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.036
macromolecule catabolic process GO:0009057 281 0.035
cellular response to biotic stimulus GO:0071216 92 0.035
apoptotic signaling pathway GO:0097190 306 0.035
adult walking behavior GO:0007628 41 0.035
cd4 positive alpha beta t cell lineage commitment GO:0043373 6 0.035
mesenchyme development GO:0060485 152 0.035
regulation of fatty acid transport GO:2000191 10 0.035
t cell differentiation involved in immune response GO:0002292 30 0.035
nitrogen compound transport GO:0071705 271 0.035
regulation of purine nucleotide biosynthetic process GO:1900371 34 0.035
negative regulation of secretion GO:0051048 61 0.035
regulation of kinase activity GO:0043549 249 0.034
fatty acid transport GO:0015908 28 0.034
regulation of canonical wnt signaling pathway GO:0060828 82 0.034
cellular response to external stimulus GO:0071496 88 0.034
response to nutrient levels GO:0031667 109 0.034
sa node cell action potential GO:0086015 4 0.034
regulation of epithelial cell proliferation GO:0050678 141 0.034
activation of immune response GO:0002253 138 0.033
regulation of ossification GO:0030278 112 0.033
regulation of protein kinase activity GO:0045859 232 0.033
cellular response to lipid GO:0071396 145 0.033
regulation of binding GO:0051098 111 0.033
habituation GO:0046959 3 0.033
epithelial cell development GO:0002064 159 0.033
immune response regulating signaling pathway GO:0002764 125 0.033
calcium mediated signaling GO:0019722 46 0.033
tube formation GO:0035148 140 0.033
molting cycle GO:0042303 90 0.033
positive regulation of organelle organization GO:0010638 128 0.033
stem cell development GO:0048864 219 0.033
multicellular organismal response to stress GO:0033555 62 0.033
positive regulation of granulocyte chemotaxis GO:0071624 12 0.032
positive regulation of apoptotic process GO:0043065 217 0.032
skeletal system morphogenesis GO:0048705 203 0.032
cerebral cortex gabaergic interneuron differentiation GO:0021892 9 0.032
cellular response to cytokine stimulus GO:0071345 189 0.032
response to peptide GO:1901652 136 0.032
nuclear transport GO:0051169 139 0.032
regulation of skeletal muscle fiber development GO:0048742 36 0.032
neutrophil migration GO:1990266 37 0.032
response to pain GO:0048265 26 0.032
positive regulation of protein modification process GO:0031401 299 0.032
bone morphogenesis GO:0060349 78 0.032
regulation of heart rate GO:0002027 36 0.031
learning or memory GO:0007611 148 0.031
regulation of camp metabolic process GO:0030814 30 0.031
cell maturation GO:0048469 127 0.031
alpha beta t cell lineage commitment GO:0002363 7 0.031
nucleoside phosphate metabolic process GO:0006753 338 0.031
myotube cell development GO:0014904 60 0.031
vascular endothelial growth factor production GO:0010573 13 0.031
ameboidal type cell migration GO:0001667 128 0.030
l amino acid transport GO:0015807 32 0.030
cellular ion homeostasis GO:0006873 165 0.030
regulation of systemic arterial blood pressure GO:0003073 61 0.030
nephron epithelium development GO:0072009 92 0.030
fatty acid derivative transport GO:1901571 14 0.030
purine containing compound metabolic process GO:0072521 311 0.029
exocytosis GO:0006887 121 0.029
glycoprotein metabolic process GO:0009100 116 0.029
regulation of t helper cell differentiation GO:0045622 14 0.029
regulation of cd4 positive alpha beta t cell differentiation GO:0043370 21 0.029
inflammatory response to wounding GO:0090594 4 0.029
positive regulation of angiogenesis GO:0045766 46 0.029
bmp signaling pathway GO:0030509 93 0.029
antigen receptor mediated signaling pathway GO:0050851 64 0.029
regulation of alpha beta t cell differentiation GO:0046637 35 0.029
metanephric loop of henle development GO:0072236 4 0.029
heart process GO:0003015 94 0.028
response to tumor necrosis factor GO:0034612 26 0.028
negative regulation of synapse assembly GO:0051964 3 0.028
renal tubule development GO:0061326 87 0.028
regulation of cell cycle GO:0051726 281 0.028
positive regulation of phagocytosis GO:0050766 26 0.028
dendritic cell differentiation GO:0097028 26 0.028
negative regulation of interleukin 5 production GO:0032714 4 0.028
morphogenesis of embryonic epithelium GO:0016331 159 0.028
telencephalon development GO:0021537 186 0.028
muscle tissue development GO:0060537 308 0.028
lymphocyte activation involved in immune response GO:0002285 93 0.028
epithelial cell morphogenesis GO:0003382 41 0.028
protein localization to organelle GO:0033365 185 0.028
cell adhesion GO:0007155 329 0.028
canonical wnt signaling pathway GO:0060070 130 0.028
regulation of peptide secretion GO:0002791 77 0.028
regulation of vascular endothelial growth factor production GO:0010574 13 0.028
myotube differentiation GO:0014902 105 0.028
neural tube closure GO:0001843 90 0.028
regulation of protein catabolic process GO:0042176 108 0.027
membrane depolarization during sa node cell action potential GO:0086046 2 0.027
kidney morphogenesis GO:0060993 83 0.027
positive regulation of inflammatory response GO:0050729 47 0.027
posttranscriptional regulation of gene expression GO:0010608 155 0.027
divalent metal ion transport GO:0070838 172 0.027
sterol transport GO:0015918 38 0.027
single organism cell adhesion GO:0098602 156 0.027
inorganic ion transmembrane transport GO:0098660 234 0.027
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway GO:0051482 4 0.027
detection of abiotic stimulus GO:0009582 60 0.026
regulation of tube size GO:0035150 57 0.026
monoamine transport GO:0015844 33 0.026
positive regulation of apoptotic signaling pathway GO:2001235 95 0.026
oocyte construction GO:0007308 2 0.026
regulation of lymphocyte differentiation GO:0045619 107 0.026
forebrain cell migration GO:0021885 58 0.026
macromolecule glycosylation GO:0043413 55 0.026
multi organism behavior GO:0051705 62 0.026
positive regulation of behavior GO:0048520 40 0.026
erythrocyte differentiation GO:0030218 88 0.026
membrane depolarization GO:0051899 64 0.026
protein import GO:0017038 101 0.026
bone remodeling GO:0046849 53 0.026
organic hydroxy compound biosynthetic process GO:1901617 77 0.026
regulation of synaptic plasticity GO:0048167 87 0.026
neuron migration GO:0001764 122 0.026
t cell differentiation GO:0030217 174 0.026
limbic system development GO:0021761 72 0.026
nephron tubule development GO:0072080 84 0.026
fibroblast growth factor production GO:0090269 4 0.025
regulation of synaptic transmission glutamatergic GO:0051966 19 0.025
inorganic cation transmembrane transport GO:0098662 207 0.025
purine ribonucleotide biosynthetic process GO:0009152 59 0.025
regulation of interleukin 10 production GO:0032653 21 0.025
dopamine metabolic process GO:0042417 23 0.025
regulation of stress activated mapk cascade GO:0032872 69 0.025
ectoderm formation GO:0001705 3 0.025
hair follicle development GO:0001942 85 0.025
norepinephrine secretion GO:0048243 2 0.025
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.025
response to oxidative stress GO:0006979 123 0.025
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.025
positive regulation of syncytium formation by plasma membrane fusion GO:0060143 17 0.025
response to interleukin 1 GO:0070555 11 0.025
negative regulation of inflammatory response GO:0050728 61 0.025
ureteric bud development GO:0001657 94 0.025

Il12b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.041
musculoskeletal system disease DOID:17 0 0.041
connective tissue disease DOID:65 0 0.034