Mus musculus

39 known processes

Il12rb2

interleukin 12 receptor, beta 2

(Aliases: IL-12RB2,Ifnm,A930027I18Rik)

Il12rb2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cellular response to cytokine stimulus GO:0071345 189 0.622
Mouse
regulation of cytokine production GO:0001817 266 0.608
Human Mouse
carbohydrate derivative biosynthetic process GO:1901137 183 0.579
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.570
Mouse
cytokine production GO:0001816 319 0.567
cytokine mediated signaling pathway GO:0019221 115 0.495
Mouse
regulation of adaptive immune response GO:0002819 90 0.469
Mouse
regulation of leukocyte mediated immunity GO:0002703 104 0.416
Mouse
gland development GO:0048732 330 0.397
response to molecule of bacterial origin GO:0002237 143 0.396
positive regulation of monocyte chemotaxis GO:0090026 2 0.393
regulation of cell activation GO:0050865 289 0.390
Mouse
regulation of secretion GO:0051046 274 0.378
regulation of cellular amino acid metabolic process GO:0006521 5 0.374
divalent inorganic cation homeostasis GO:0072507 138 0.373
positive regulation of immunological synapse formation GO:2000522 1 0.359
regulation of defense response GO:0031347 233 0.338
amine metabolic process GO:0009308 45 0.337
regulation of protein secretion GO:0050708 82 0.337
response to lipopolysaccharide GO:0032496 128 0.330
interleukin 12 secretion GO:0072610 3 0.328
forebrain development GO:0030900 302 0.319
regulation of leukocyte proliferation GO:0070663 121 0.301
regulation of interferon gamma production GO:0032649 57 0.298
Human Mouse
leukocyte proliferation GO:0070661 172 0.289
regulation of protein transport GO:0051223 163 0.287
immune effector process GO:0002252 321 0.287
Mouse
regulation of protein localization GO:0032880 231 0.281
g protein coupled receptor signaling pathway GO:0007186 243 0.278
eosinophil activation GO:0043307 1 0.278
positive regulation of leukocyte proliferation GO:0070665 73 0.269
regulation of membrane potential GO:0042391 192 0.269
organic anion transport GO:0015711 137 0.252
t cell activation GO:0042110 289 0.250
inflammatory response GO:0006954 244 0.245
t cell extravasation GO:0072683 4 0.239
innate immune response GO:0045087 157 0.238
regulation of inflammatory response GO:0050727 147 0.235
protein secretion GO:0009306 111 0.231
adaptive immune response GO:0002250 155 0.228
Mouse
eosinophil degranulation GO:0043308 1 0.228
regulation of monocyte chemotaxis GO:0090025 3 0.223
regulation of establishment of protein localization GO:0070201 181 0.218
interleukin 1 production GO:0032612 31 0.218
release of sequestered calcium ion into cytosol GO:0051209 42 0.208
regulation of lymphocyte proliferation GO:0050670 117 0.202
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.202
regulation of cellular amine metabolic process GO:0033238 20 0.202
eosinophil activation involved in immune response GO:0002278 1 0.200
eosinophil mediated immunity GO:0002447 1 0.195
positive regulation of secretion GO:0051047 130 0.193
positive regulation of lymphocyte proliferation GO:0050671 70 0.191
peptidyl tyrosine phosphorylation GO:0018108 143 0.189
t helper 17 cell chemotaxis GO:0035705 1 0.189
leukocyte activation involved in immune response GO:0002366 126 0.187
Mouse
sequestering of metal ion GO:0051238 19 0.187
regulation of t cell proliferation GO:0042129 92 0.183
cell type specific apoptotic process GO:0097285 268 0.181
regulation of immunological synapse formation GO:2000520 2 0.180
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.179
Mouse
regulation of response to wounding GO:1903034 189 0.178
cell activation involved in immune response GO:0002263 126 0.177
Mouse
hematopoietic stem cell migration GO:0035701 1 0.177
regulation of innate immune response GO:0045088 91 0.174
positive regulation of protein modification process GO:0031401 299 0.173
t helper 1 type immune response GO:0042088 25 0.172
Mouse
regulation of cytokine secretion GO:0050707 61 0.172
sequestering of calcium ion GO:0051208 18 0.171
calcium ion homeostasis GO:0055074 127 0.170
positive regulation of inflammatory response GO:0050729 47 0.169
cellular amine metabolic process GO:0044106 44 0.168
cellular response to lipopolysaccharide GO:0071222 77 0.167
cation transport GO:0006812 399 0.164
membrane organization GO:0061024 245 0.163
positive regulation of t cell costimulation GO:2000525 2 0.161
regulation of interleukin 1 beta production GO:0032651 25 0.159
regulation of monocyte extravasation GO:2000437 2 0.159
regulation of lymphocyte mediated immunity GO:0002706 84 0.159
Mouse
glycoprotein biosynthetic process GO:0009101 89 0.158
apoptotic signaling pathway GO:0097190 306 0.156
lymphocyte proliferation GO:0046651 164 0.155
epithelial cell proliferation GO:0050673 174 0.155
negative regulation of eosinophil degranulation GO:0043310 1 0.153
lymphocyte activation involved in immune response GO:0002285 93 0.152
Mouse
positive regulation of t cell receptor signaling pathway GO:0050862 4 0.151
monocyte extravasation GO:0035696 2 0.151
regulation of t cell extravasation GO:2000407 3 0.151
defense response to other organism GO:0098542 197 0.148
Mouse
response to organic cyclic compound GO:0014070 198 0.146
myeloid leukocyte migration GO:0097529 57 0.145
Mouse
regulation of ion homeostasis GO:2000021 64 0.145
negative regulation of defense response GO:0031348 77 0.145
regulation of lymphocyte activation GO:0051249 240 0.142
Mouse
b cell activation GO:0042113 161 0.141
Mouse
interferon gamma production GO:0032609 67 0.140
carboxylic acid transport GO:0046942 100 0.140
t cell proliferation GO:0042098 120 0.140
cellular divalent inorganic cation homeostasis GO:0072503 127 0.139
endomembrane system organization GO:0010256 147 0.138
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation GO:2000526 1 0.136
mature dendritic cell differentiation GO:0097029 3 0.136
regulation of t cell costimulation GO:2000523 2 0.135
extrinsic apoptotic signaling pathway GO:0097191 126 0.134
cellular ketone metabolic process GO:0042180 84 0.133
regulation of t helper 1 type immune response GO:0002825 17 0.131
Mouse
regulation of dendritic cell chemotaxis GO:2000508 1 0.131
leukocyte differentiation GO:0002521 342 0.130
regulation of cellular ketone metabolic process GO:0010565 66 0.130
positive regulation of cytokine production GO:0001819 174 0.129
Human Mouse
positive regulation of t helper 1 type immune response GO:0002827 12 0.129
Mouse
microglial cell activation involved in immune response GO:0002282 1 0.129
regulation of secretion by cell GO:1903530 249 0.123
positive regulation of cd8 positive alpha beta t cell extravasation GO:2000451 2 0.123
cytokine secretion GO:0050663 72 0.122
regulation of hematopoietic stem cell migration GO:2000471 1 0.122
positive regulation of monocyte extravasation GO:2000439 1 0.122
negative regulation of secretion GO:0051048 61 0.121
leukocyte mediated immunity GO:0002443 174 0.121
Mouse
positive regulation of cellular amine metabolic process GO:0033240 5 0.120
cd8 positive alpha beta t cell extravasation GO:0035697 3 0.119
regulation of production of molecular mediator of immune response GO:0002700 65 0.118
Mouse
positive regulation of t cell extravasation GO:2000409 2 0.115
defense response to gram positive bacterium GO:0050830 50 0.115
Mouse
anion transport GO:0006820 177 0.115
glycoprotein metabolic process GO:0009100 116 0.114
positive regulation of cell activation GO:0050867 158 0.114
positive regulation of interleukin 12 production GO:0032735 21 0.114
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.112
Mouse
neuronal action potential GO:0019228 54 0.112
positive regulation of immune complex clearance by monocytes and macrophages GO:0090265 2 0.112
humoral immune response GO:0006959 57 0.110
cellular response to molecule of bacterial origin GO:0071219 83 0.109
defense response to bacterium GO:0042742 119 0.108
Mouse
positive regulation of mapk cascade GO:0043410 170 0.107
dna metabolic process GO:0006259 303 0.103
Mouse
positive regulation of defense response GO:0031349 124 0.103
response to organonitrogen compound GO:0010243 246 0.102
myeloid cell differentiation GO:0030099 233 0.102
mapk cascade GO:0000165 281 0.102
positive regulation of t cell proliferation GO:0042102 52 0.101
positive regulation of adaptive immune response GO:0002821 61 0.101
Mouse
morphogenesis of a branching epithelium GO:0061138 193 0.100
regulation of immune complex clearance by monocytes and macrophages GO:0090264 2 0.100
lymphocyte mediated immunity GO:0002449 139 0.100
Mouse
regulation of hormone levels GO:0010817 211 0.099
positive regulation of interferon gamma production GO:0032729 39 0.098
Human Mouse
negative regulation of macrophage apoptotic process GO:2000110 3 0.097
sperm individualization GO:0007291 1 0.097
cellular calcium ion homeostasis GO:0006874 119 0.097
regulation of t cell activation GO:0050863 170 0.097
regulation of inflammatory response to antigenic stimulus GO:0002861 21 0.096
negative regulation of phosphate metabolic process GO:0045936 184 0.096
positive regulation of t cell activation GO:0050870 101 0.094
activation of immune response GO:0002253 138 0.094
granzyme mediated apoptotic signaling pathway GO:0008626 1 0.094
defense response to virus GO:0051607 68 0.094
skin development GO:0043588 220 0.093
regulation of cytokine biosynthetic process GO:0042035 59 0.092
regulation of b cell activation GO:0050864 81 0.091
Mouse
regulation of vesicle mediated transport GO:0060627 139 0.090
immune complex clearance by monocytes and macrophages GO:0002436 2 0.090
positive regulation of secretion by cell GO:1903532 114 0.089
positive regulation of lymphocyte activation GO:0051251 140 0.089
endocytosis GO:0006897 168 0.088
synaptic transmission GO:0007268 329 0.088
negative regulation of cytokine production GO:0001818 84 0.087
production of molecular mediator of immune response GO:0002440 103 0.086
Mouse
positive regulation of dendritic cell chemotaxis GO:2000510 1 0.084
i kappab kinase nf kappab signaling GO:0007249 85 0.083
regulation of interleukin 12 production GO:0032655 30 0.083
divalent inorganic cation transport GO:0072511 178 0.082
cellular response to organonitrogen compound GO:0071417 145 0.082
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.081
interleukin 1 beta production GO:0032611 30 0.081
positive regulation of tumor necrosis factor production GO:0032760 30 0.081
regulation of cell migration GO:0030334 219 0.081
circulatory system process GO:0003013 197 0.079
calcium ion transport into cytosol GO:0060402 48 0.079
plasma membrane organization GO:0007009 90 0.079
acid secretion GO:0046717 33 0.078
sensory perception of pain GO:0019233 47 0.078
negative regulation of growth GO:0045926 99 0.076
t helper 2 cell cytokine production GO:0035745 4 0.076
leukocyte migration GO:0050900 124 0.076
Mouse
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.075
organic hydroxy compound metabolic process GO:1901615 203 0.074
transmission of nerve impulse GO:0019226 76 0.073
regulation of b cell mediated immunity GO:0002712 37 0.072
Mouse
positive regulation of response to wounding GO:1903036 66 0.071
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 26 0.070
type 2 immune response GO:0042092 23 0.070
Mouse
regulation of homeostatic process GO:0032844 182 0.070
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 31 0.070
negative regulation of homeostatic process GO:0032845 71 0.069
granulocyte chemotaxis GO:0071621 39 0.068
Mouse
immunoglobulin production GO:0002377 73 0.068
Mouse
regulation of systemic arterial blood pressure GO:0003073 61 0.068
microglial cell activation GO:0001774 3 0.067
epithelial tube morphogenesis GO:0060562 303 0.066
regulation of interleukin 1 production GO:0032652 26 0.066
signal transduction in absence of ligand GO:0038034 55 0.066
regulation of epithelial cell proliferation GO:0050678 141 0.066
cellular amino acid metabolic process GO:0006520 103 0.066
inflammatory response to antigenic stimulus GO:0002437 30 0.065
blood circulation GO:0008015 195 0.065
cellular homeostasis GO:0019725 240 0.065
cellularization GO:0007349 1 0.064
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.064
axonogenesis GO:0007409 274 0.063
positive regulation of behavior GO:0048520 40 0.063
regulation of cytoplasmic transport GO:1903649 112 0.063
second messenger mediated signaling GO:0019932 73 0.063
divalent metal ion transport GO:0070838 172 0.063
reactive oxygen species metabolic process GO:0072593 84 0.062
cellular ion homeostasis GO:0006873 165 0.062
single organism nuclear import GO:1902593 95 0.062
positive regulation of neutrophil chemotaxis GO:0090023 12 0.062
regulation of type 2 immune response GO:0002828 18 0.061
Mouse
regulation of tumor necrosis factor production GO:0032680 49 0.061
immune complex clearance GO:0002434 2 0.061
myeloid leukocyte differentiation GO:0002573 119 0.061
cellular metal ion homeostasis GO:0006875 151 0.060
regulation of eosinophil degranulation GO:0043309 1 0.060
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.060
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.060
epidermis development GO:0008544 187 0.059
calcium ion transport GO:0006816 159 0.058
negative regulation of protein transport GO:0051224 46 0.058
stress activated mapk cascade GO:0051403 80 0.058
organic cyclic compound catabolic process GO:1901361 295 0.057
glial cell apoptotic process GO:0034349 3 0.056
positive regulation of cytokine biosynthetic process GO:0042108 40 0.055
positive regulation of programmed cell death GO:0043068 218 0.055
peptidyl amino acid modification GO:0018193 336 0.055
norepinephrine secretion GO:0048243 2 0.055
neutrophil migration GO:1990266 37 0.054
Mouse
immune response activating signal transduction GO:0002757 116 0.054
regulation of kinase activity GO:0043549 249 0.054
cellular response to hormone stimulus GO:0032870 150 0.054
interleukin 12 production GO:0032615 32 0.054
positive regulation of hydrolase activity GO:0051345 148 0.053
forebrain cell migration GO:0021885 58 0.053
positive regulation of immune effector process GO:0002699 107 0.053
lipid localization GO:0010876 126 0.052
cytokine metabolic process GO:0042107 71 0.051
cytosolic calcium ion transport GO:0060401 48 0.051
organic acid transport GO:0015849 101 0.051
interleukin 2 production GO:0032623 33 0.051
organic hydroxy compound transport GO:0015850 93 0.050
immune response regulating signaling pathway GO:0002764 125 0.050
action potential GO:0001508 78 0.050
activation of adenylate cyclase activity GO:0007190 4 0.049
protein localization to nucleus GO:0034504 121 0.049
cation homeostasis GO:0055080 212 0.049
peptidyl tyrosine modification GO:0018212 145 0.049
regulation of leukocyte mediated cytotoxicity GO:0001910 38 0.049
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.048
cell chemotaxis GO:0060326 81 0.047
Mouse
regulation of leukocyte differentiation GO:1902105 159 0.047
response to tumor necrosis factor GO:0034612 26 0.047
cytokine biosynthetic process GO:0042089 68 0.047
positive regulation of hematopoietic stem cell migration GO:2000473 1 0.047
cellular response to lipid GO:0071396 145 0.046
positive regulation of protein phosphorylation GO:0001934 242 0.046
negative regulation of interleukin 5 production GO:0032714 4 0.045
positive regulation of granulocyte chemotaxis GO:0071624 12 0.045
cognition GO:0050890 149 0.045
cellular response to amino acid stimulus GO:0071230 29 0.045
regulation of endocytosis GO:0030100 69 0.045
organonitrogen compound catabolic process GO:1901565 264 0.045
negative regulation of phosphorus metabolic process GO:0010563 184 0.045
negative regulation of myeloid cell apoptotic process GO:0033033 11 0.045
regulation of neutrophil chemotaxis GO:0090022 14 0.045
protein localization to organelle GO:0033365 185 0.045
b cell proliferation GO:0042100 53 0.045
pallium development GO:0021543 120 0.045
tumor necrosis factor production GO:0032640 50 0.044
multicellular organismal signaling GO:0035637 91 0.044
regulation of multi organism process GO:0043900 111 0.044
neuron migration GO:0001764 122 0.044
fatty acid biosynthetic process GO:0006633 41 0.042
muscle contraction GO:0006936 101 0.042
chemotaxis GO:0006935 247 0.042
Mouse
regulation of systemic arterial blood pressure by hormone GO:0001990 25 0.041
maintenance of location GO:0051235 89 0.041
monocarboxylic acid transport GO:0015718 44 0.041
regulation of antigen receptor mediated signaling pathway GO:0050854 29 0.041
regulation of interleukin 2 production GO:0032663 28 0.041
monocarboxylic acid metabolic process GO:0032787 191 0.040
regulation of alpha beta t cell proliferation GO:0046640 18 0.040
nucleotide metabolic process GO:0009117 332 0.040
cytoplasmic transport GO:0016482 234 0.039
regulation of lymphocyte differentiation GO:0045619 107 0.039
nitrogen compound transport GO:0071705 271 0.039
fatty acid transport GO:0015908 28 0.039
negative regulation of immune system process GO:0002683 209 0.039
Mouse
protein targeting GO:0006605 143 0.039
regulation of mapk cascade GO:0043408 248 0.039
metal ion homeostasis GO:0055065 189 0.039
stress activated protein kinase signaling cascade GO:0031098 81 0.039
regulation of angiotensin levels in blood GO:0002002 4 0.038
regulation of myeloid leukocyte differentiation GO:0002761 58 0.038
regulation of blood pressure GO:0008217 93 0.038
negative regulation of secretion by cell GO:1903531 54 0.038
interleukin 1 secretion GO:0050701 16 0.038
regulation of neutrophil migration GO:1902622 14 0.037
gliogenesis GO:0042063 141 0.037
Mouse
endocrine process GO:0050886 39 0.037
acute inflammatory response GO:0002526 41 0.037
lymphocyte costimulation GO:0031294 15 0.037
regulation of cell motility GO:2000145 236 0.037
positive regulation of neutrophil migration GO:1902624 12 0.036
myelination GO:0042552 74 0.036
nucleocytoplasmic transport GO:0006913 139 0.036
male gamete generation GO:0048232 285 0.036
response to radiation GO:0009314 165 0.036
regulation of protein kinase activity GO:0045859 232 0.036
lipid transport GO:0006869 98 0.036
rhythmic process GO:0048511 174 0.036
nuclear transport GO:0051169 139 0.035
regulation of endothelial cell proliferation GO:0001936 23 0.035
morphogenesis of a branching structure GO:0001763 203 0.035
multicellular organism growth GO:0035264 161 0.035
regulation of system process GO:0044057 200 0.034
alpha beta t cell activation GO:0046631 91 0.034
cellular response to biotic stimulus GO:0071216 92 0.034
negative regulation of cellular amine metabolic process GO:0033239 1 0.034
cellular nitrogen compound catabolic process GO:0044270 280 0.034
regulation of t helper 2 cell cytokine production GO:2000551 3 0.033
antibacterial peptide biosynthetic process GO:0002780 2 0.033
positive regulation of alpha beta t cell proliferation GO:0046641 12 0.033
cellular response to tumor necrosis factor GO:0071356 21 0.032
receptor mediated endocytosis GO:0006898 51 0.032
sensory perception GO:0007600 245 0.032
t cell mediated immunity GO:0002456 50 0.032
glycosyl compound metabolic process GO:1901657 246 0.032
neutrophil mediated killing of gram positive bacterium GO:0070946 2 0.032
intracellular protein transport GO:0006886 204 0.031
b cell differentiation GO:0030183 78 0.031
positive regulation of gliogenesis GO:0014015 27 0.031
Mouse
learning or memory GO:0007611 148 0.031
lymphocyte differentiation GO:0030098 242 0.031
regulation of ion transport GO:0043269 215 0.031
purine ribonucleotide metabolic process GO:0009150 290 0.031
antigen receptor mediated signaling pathway GO:0050851 64 0.030
engulfment of apoptotic cell GO:0043652 3 0.030
ion transmembrane transport GO:0034220 361 0.030
positive regulation of leukocyte mediated immunity GO:0002705 70 0.030
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.030
regulation of chemotaxis GO:0050920 53 0.030
anatomical structure homeostasis GO:0060249 145 0.030
cerebral cortex development GO:0021987 86 0.030
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.030
regulation of body fluid levels GO:0050878 162 0.030
g protein coupled receptor internalization GO:0002031 3 0.030
regulation of vascular endothelial growth factor production GO:0010574 13 0.030
cellular response to dna damage stimulus GO:0006974 207 0.030
regulation of cysteine type endopeptidase activity GO:2000116 65 0.029
t cell receptor signaling pathway GO:0050852 46 0.029
dendritic cell chemotaxis GO:0002407 7 0.029
hexose transport GO:0008645 56 0.029
dna recombination GO:0006310 92 0.029
Mouse
antibacterial peptide production GO:0002778 2 0.029
multicellular organismal response to stress GO:0033555 62 0.029
protein kinase c activating g protein coupled receptor signaling pathway GO:0007205 4 0.028
growth of symbiont in host GO:0044117 23 0.028
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.028
rho protein signal transduction GO:0007266 32 0.028
regulation of interleukin 5 secretion GO:2000662 2 0.028
nuclear import GO:0051170 95 0.028
cellular lipid metabolic process GO:0044255 323 0.028
negative regulation of type 2 immune response GO:0002829 8 0.028
Mouse
positive regulation of nervous system development GO:0051962 221 0.028
Mouse
positive regulation of epithelial cell proliferation GO:0050679 68 0.028
isotype switching GO:0045190 36 0.028
Mouse
positive regulation of cytokine secretion GO:0050715 41 0.028
regulation of glial cell differentiation GO:0045685 41 0.028
Mouse
cellular chemical homeostasis GO:0055082 215 0.028
memory GO:0007613 58 0.028
macrophage chemotaxis GO:0048246 14 0.027
blood vessel morphogenesis GO:0048514 285 0.027
inflammatory cell apoptotic process GO:0006925 11 0.027
small molecule biosynthetic process GO:0044283 132 0.027
response to acid chemical GO:0001101 111 0.027
hormone secretion GO:0046879 128 0.027
germ cell development GO:0007281 185 0.027
regulation of alpha beta t cell activation GO:0046634 53 0.027
positive regulation of ion transport GO:0043270 65 0.027
regulation of granulocyte chemotaxis GO:0071622 17 0.027
regulation of organelle organization GO:0033043 289 0.027
interleukin 1 beta secretion GO:0050702 16 0.027
ribonucleotide metabolic process GO:0009259 291 0.027
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.027
regulation of norepinephrine secretion GO:0014061 2 0.027
negative regulation of intracellular signal transduction GO:1902532 167 0.026
regulation of cellular response to stress GO:0080135 159 0.026
eosinophil migration GO:0072677 3 0.026
somatic diversification of immune receptors GO:0002200 53 0.026
Mouse
cell fate commitment GO:0045165 210 0.026
purine containing compound metabolic process GO:0072521 311 0.026
positive regulation of inflammatory response to antigenic stimulus GO:0002863 11 0.026
lymphocyte migration GO:0072676 26 0.026
telencephalon cell migration GO:0022029 55 0.026
regulation of acute inflammatory response GO:0002673 27 0.026
actin cytoskeleton organization GO:0030036 220 0.026
glycosyl compound catabolic process GO:1901658 206 0.025
macrophage apoptotic process GO:0071888 7 0.025
t cell costimulation GO:0031295 14 0.025
erk1 and erk2 cascade GO:0070371 77 0.025
transepithelial chloride transport GO:0030321 4 0.025
regulation of interleukin 13 secretion GO:2000665 2 0.025
monocarboxylic acid biosynthetic process GO:0072330 61 0.025
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.025
positive regulation of protein kinase activity GO:0045860 144 0.025
aromatic compound catabolic process GO:0019439 286 0.025
nucleobase containing small molecule metabolic process GO:0055086 352 0.025
branching morphogenesis of an epithelial tube GO:0048754 159 0.025
posttranscriptional regulation of gene expression GO:0010608 155 0.025
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.025
regulation of dna recombination GO:0000018 34 0.025
Mouse
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.024
vascular endothelial growth factor production GO:0010573 13 0.024
liver development GO:0001889 66 0.024
purine nucleoside triphosphate metabolic process GO:0009144 226 0.024
regulation of intracellular protein transport GO:0033157 82 0.024
granulocyte migration GO:0097530 43 0.024
Mouse
mitotic cell cycle process GO:1903047 159 0.024
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.024
Mouse
calcium mediated signaling GO:0019722 46 0.024
interspecies interaction between organisms GO:0044419 83 0.024
jnk cascade GO:0007254 72 0.024
digestive system development GO:0055123 200 0.023
regulation of hydrolase activity GO:0051336 246 0.023
cytosolic calcium ion homeostasis GO:0051480 70 0.023
urogenital system development GO:0001655 261 0.023
negative regulation of phosphorylation GO:0042326 166 0.023
negative regulation of leukocyte mediated immunity GO:0002704 29 0.023
purine nucleotide biosynthetic process GO:0006164 65 0.023
spermatid development GO:0007286 108 0.023
leukocyte apoptotic process GO:0071887 71 0.023
cell killing GO:0001906 67 0.023
regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 33 0.023
regulation of apoptotic signaling pathway GO:2001233 197 0.023
heart contraction GO:0060047 93 0.023
regulation of proteolysis GO:0030162 164 0.023
regulation of glycoprotein biosynthetic process GO:0010559 12 0.023
corticotropin releasing hormone secretion GO:0043396 2 0.023
protein import into nucleus GO:0006606 95 0.023
oxidation reduction process GO:0055114 342 0.022
Mouse
myeloid cell apoptotic process GO:0033028 22 0.022
digestion GO:0007586 40 0.022
cellular protein complex disassembly GO:0043624 36 0.022
positive regulation of b cell mediated immunity GO:0002714 26 0.022
negative regulation of t cell activation GO:0050868 65 0.022
positive regulation of innate immune response GO:0045089 80 0.022
immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 43 0.022
Mouse
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.022
purine containing compound catabolic process GO:0072523 213 0.022
organonitrogen compound biosynthetic process GO:1901566 192 0.022
chromatin modification GO:0016568 187 0.022
negative regulation of molecular function GO:0044092 258 0.022
regulation of interleukin 1 secretion GO:0050704 15 0.022
regulation of immunoglobulin mediated immune response GO:0002889 37 0.022
Mouse
regulation of peptidase activity GO:0052547 96 0.022
fatty acid derivative metabolic process GO:1901568 33 0.022
fat cell differentiation GO:0045444 160 0.021
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.021
regulation of cellular catabolic process GO:0031329 242 0.021
regulation of exocytosis GO:0017157 61 0.021
positive regulation of chemotaxis GO:0050921 38 0.021
regulation of cell cycle GO:0051726 281 0.021
cellular response to acid chemical GO:0071229 68 0.021
reactive oxygen species biosynthetic process GO:1903409 8 0.021
response to alcohol GO:0097305 48 0.021
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.021
cartilage development GO:0051216 140 0.021
alcohol metabolic process GO:0006066 116 0.021
regulation of protein localization to nucleus GO:1900180 60 0.021
natural killer cell activation GO:0030101 44 0.021
wnt signaling pathway GO:0016055 188 0.021
conditioned taste aversion GO:0001661 4 0.021
photoreceptor cell differentiation GO:0046530 52 0.021
regulation of purine nucleotide metabolic process GO:1900542 169 0.021
organophosphate catabolic process GO:0046434 232 0.021
negative regulation of protein metabolic process GO:0051248 282 0.021
regulation of nucleocytoplasmic transport GO:0046822 73 0.021
positive regulation of jnk cascade GO:0046330 46 0.021
organophosphate biosynthetic process GO:0090407 122 0.021
regulation of growth of symbiont in host GO:0044126 19 0.021
negative regulation of cellular protein metabolic process GO:0032269 247 0.021
positive regulation of leukocyte differentiation GO:1902107 86 0.020
regulation of map kinase activity GO:0043405 120 0.020
regulation of humoral immune response GO:0002920 22 0.020
response to interferon gamma GO:0034341 34 0.020
chemokine mediated signaling pathway GO:0070098 17 0.020
t cell differentiation GO:0030217 174 0.020
icosanoid transport GO:0071715 14 0.020

Il12rb2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.054
disease of anatomical entity DOID:7 0 0.054