|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.948
|
Mouse |
|
|
stimulatory c type lectin receptor signaling pathway
|
GO:0002223 |
2 |
0.934
|
|
|
|
cell surface pattern recognition receptor signaling pathway
|
GO:0002752 |
2 |
0.923
|
|
|
|
detection of fungus
|
GO:0016046 |
2 |
0.902
|
|
|
|
natural killer cell activation
|
GO:0030101 |
44 |
0.887
|
Mouse |
|
|
detection of yeast
|
GO:0001879 |
2 |
0.865
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.856
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.850
|
Mouse |
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.847
|
Mouse |
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.830
|
|
|
|
defense response to gram positive bacterium
|
GO:0050830 |
50 |
0.811
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.806
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.775
|
Mouse |
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.772
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.767
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.757
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.747
|
Mouse |
|
|
immune effector process
|
GO:0002252 |
321 |
0.745
|
Mouse |
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.745
|
Mouse |
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.691
|
Mouse |
|
|
positive regulation of inflammatory response
|
GO:0050729 |
47 |
0.690
|
Mouse |
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.680
|
|
|
|
myeloid leukocyte mediated immunity
|
GO:0002444 |
42 |
0.678
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.671
|
Mouse |
|
|
cell killing
|
GO:0001906 |
67 |
0.666
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.650
|
Mouse |
|
|
cd8 positive alpha beta t cell extravasation
|
GO:0035697 |
3 |
0.640
|
|
|
|
leukocyte mediated cytotoxicity
|
GO:0001909 |
62 |
0.626
|
|
|
|
positive regulation of t cell costimulation
|
GO:2000525 |
2 |
0.601
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.600
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.594
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.581
|
|
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.579
|
Mouse |
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.566
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.560
|
Mouse |
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
39 |
0.557
|
Mouse |
|
|
regulation of leukocyte mediated cytotoxicity
|
GO:0001910 |
38 |
0.549
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.547
|
Mouse |
|
|
regulation of t cell extravasation
|
GO:2000407 |
3 |
0.544
|
|
|
|
regulation of natural killer cell mediated immunity
|
GO:0002715 |
19 |
0.532
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.530
|
Mouse |
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.530
|
Mouse |
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.527
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
57 |
0.518
|
|
|
|
positive regulation of monocyte chemotaxis
|
GO:0090026 |
2 |
0.513
|
|
|
|
positive regulation of leukocyte mediated cytotoxicity
|
GO:0001912 |
31 |
0.511
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.511
|
|
|
|
mature dendritic cell differentiation
|
GO:0097029 |
3 |
0.511
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.506
|
Mouse |
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.486
|
Mouse |
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
70 |
0.484
|
|
|
|
regulation of cd8 positive alpha beta t cell extravasation
|
GO:2000449 |
3 |
0.479
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.475
|
|
|
|
cellular response to molecule of fungal origin
|
GO:0071226 |
2 |
0.467
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.453
|
Mouse |
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.448
|
Mouse |
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.443
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.441
|
|
|
|
neutrophil mediated killing of gram positive bacterium
|
GO:0070946 |
2 |
0.433
|
|
|
|
natural killer cell mediated cytotoxicity
|
GO:0042267 |
29 |
0.421
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.420
|
Mouse |
|
|
interleukin 18 mediated signaling pathway
|
GO:0035655 |
2 |
0.417
|
Mouse |
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.413
|
Mouse |
|
|
response to molecule of fungal origin
|
GO:0002238 |
4 |
0.412
|
|
|
|
eosinophil activation
|
GO:0043307 |
1 |
0.397
|
|
|
|
positive regulation of immunological synapse formation
|
GO:2000522 |
1 |
0.394
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.388
|
Mouse |
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.387
|
|
|
|
helper t cell chemotaxis
|
GO:0035704 |
1 |
0.387
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.378
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.372
|
Mouse |
|
|
regulation of cytokine secretion
|
GO:0050707 |
61 |
0.372
|
Mouse |
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.372
|
Mouse |
|
|
t cell extravasation
|
GO:0072683 |
4 |
0.371
|
|
|
|
positive regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903557 |
31 |
0.371
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.370
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.369
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.358
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.351
|
Mouse |
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.347
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.342
|
|
|
|
neutrophil chemotaxis
|
GO:0030593 |
36 |
0.339
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.339
|
Mouse |
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.338
|
Mouse |
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.337
|
Mouse |
|
|
regulation of regulated secretory pathway
|
GO:1903305 |
20 |
0.334
|
|
|
|
regulation of monocyte chemotaxis
|
GO:0090025 |
3 |
0.331
|
|
|
|
regulation of chemokine production
|
GO:0032642 |
30 |
0.331
|
Mouse |
|
|
neutrophil migration
|
GO:1990266 |
37 |
0.330
|
|
|
|
interleukin 12 secretion
|
GO:0072610 |
3 |
0.328
|
|
|
|
granzyme mediated apoptotic signaling pathway
|
GO:0008626 |
1 |
0.327
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.324
|
|
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.320
|
|
|
|
granulocyte chemotaxis
|
GO:0071621 |
39 |
0.319
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.318
|
Mouse |
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.318
|
Mouse |
|
|
regulation of cell killing
|
GO:0031341 |
40 |
0.310
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.308
|
Mouse |
|
|
neutrophil mediated killing of bacterium
|
GO:0070944 |
6 |
0.299
|
|
|
|
positive regulation of t cell receptor signaling pathway
|
GO:0050862 |
4 |
0.299
|
|
|
|
positive regulation of lymphocyte mediated immunity
|
GO:0002708 |
62 |
0.298
|
|
|
|
positive regulation of response to wounding
|
GO:1903036 |
66 |
0.295
|
Mouse |
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.292
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.291
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.290
|
|
|
|
regulation of t cell costimulation
|
GO:2000523 |
2 |
0.289
|
|
|
|
positive regulation of chemokine production
|
GO:0032722 |
22 |
0.284
|
Mouse |
|
|
disruption by host of symbiont cells
|
GO:0051852 |
11 |
0.279
|
|
|
|
detection of other organism
|
GO:0098543 |
8 |
0.277
|
|
|
|
eosinophil degranulation
|
GO:0043308 |
1 |
0.277
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.275
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.275
|
Mouse |
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.271
|
|
|
|
eosinophil activation involved in immune response
|
GO:0002278 |
1 |
0.268
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.258
|
Mouse |
|
|
positive regulation of cell killing
|
GO:0031343 |
33 |
0.257
|
|
|
|
acute inflammatory response
|
GO:0002526 |
41 |
0.257
|
Mouse |
|
|
natural killer cell mediated immunity
|
GO:0002228 |
29 |
0.255
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.251
|
Mouse |
|
|
dendritic cell differentiation
|
GO:0097028 |
26 |
0.249
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.247
|
|
|
|
killing of cells in other organism involved in symbiotic interaction
|
GO:0051883 |
13 |
0.247
|
|
|
|
positive regulation of t cell extravasation
|
GO:2000409 |
2 |
0.247
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
29 |
0.245
|
|
|
|
killing of cells of other organism
|
GO:0031640 |
13 |
0.245
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.245
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.234
|
Mouse |
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.233
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.226
|
|
|
|
interaction with symbiont
|
GO:0051702 |
14 |
0.221
|
|
|
|
positive regulation of natural killer cell mediated cytotoxicity
|
GO:0045954 |
16 |
0.219
|
|
|
|
negative regulation of eosinophil degranulation
|
GO:0043310 |
1 |
0.217
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
51 |
0.217
|
|
|
|
killing by host of symbiont cells
|
GO:0051873 |
11 |
0.214
|
|
|
|
eosinophil mediated immunity
|
GO:0002447 |
1 |
0.214
|
|
|
|
regulation of t helper 1 type immune response
|
GO:0002825 |
17 |
0.214
|
Mouse |
|
|
protein secretion
|
GO:0009306 |
111 |
0.208
|
Mouse |
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.207
|
Mouse |
|
|
neutrophil mediated immunity
|
GO:0002446 |
19 |
0.207
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.200
|
|
|
|
positive regulation of monocyte extravasation
|
GO:2000439 |
1 |
0.199
|
|
|
|
positive regulation of cd8 positive alpha beta t cell extravasation
|
GO:2000451 |
2 |
0.198
|
|
|
|
regulation of dendritic cell chemotaxis
|
GO:2000508 |
1 |
0.191
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.190
|
|
|
|
negative regulation of macrophage apoptotic process
|
GO:2000110 |
3 |
0.188
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.186
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.184
|
|
|
|
chemokine production
|
GO:0032602 |
34 |
0.184
|
Mouse |
|
|
activation of immune response
|
GO:0002253 |
138 |
0.183
|
|
|
|
interleukin 2 production
|
GO:0032623 |
33 |
0.182
|
Mouse |
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
49 |
0.181
|
|
|
|
regulation of eosinophil degranulation
|
GO:0043309 |
1 |
0.180
|
|
|
|
t cell activation involved in immune response
|
GO:0002286 |
43 |
0.179
|
Mouse |
|
|
microglial cell activation involved in immune response
|
GO:0002282 |
1 |
0.176
|
|
|
|
positive regulation of natural killer cell mediated immunity
|
GO:0002717 |
16 |
0.174
|
|
|
|
neutrophil mediated cytotoxicity
|
GO:0070942 |
8 |
0.171
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.171
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.170
|
Mouse |
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.169
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.169
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.168
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.168
|
|
|
|
chemokine mediated signaling pathway
|
GO:0070098 |
17 |
0.167
|
|
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.163
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.161
|
|
|
|
defense response to virus
|
GO:0051607 |
68 |
0.161
|
|
|
|
chemokine secretion
|
GO:0090195 |
5 |
0.160
|
Mouse |
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.159
|
|
|
|
t cell mediated immunity
|
GO:0002456 |
50 |
0.158
|
|
|
|
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation
|
GO:2000526 |
1 |
0.152
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.151
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.149
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.149
|
|
|
|
positive regulation of dendritic cell chemotaxis
|
GO:2000510 |
1 |
0.148
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.146
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.146
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.145
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.145
|
|
|
|
innate immune response activating cell surface receptor signaling pathway
|
GO:0002220 |
4 |
0.144
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.144
|
|
|
|
cellular response to interleukin 15
|
GO:0071350 |
2 |
0.143
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.142
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.140
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.136
|
|
|
|
disruption of cells of other organism involved in symbiotic interaction
|
GO:0051818 |
13 |
0.136
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.135
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.135
|
|
|
|
monocyte extravasation
|
GO:0035696 |
2 |
0.134
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.134
|
Mouse |
|
|
neutrophil mediated killing of symbiont cell
|
GO:0070943 |
8 |
0.133
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.132
|
Mouse |
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.130
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.130
|
|
|
|
immune complex clearance
|
GO:0002434 |
2 |
0.129
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.129
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.128
|
|
|
|
immune complex clearance by monocytes and macrophages
|
GO:0002436 |
2 |
0.126
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.126
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
61 |
0.125
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.124
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.123
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.123
|
Mouse |
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.123
|
Mouse |
|
|
t helper 17 cell chemotaxis
|
GO:0035705 |
1 |
0.122
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.122
|
|
|
|
regulation of monocyte extravasation
|
GO:2000437 |
2 |
0.122
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.119
|
|
|
|
positive regulation of chemokine secretion
|
GO:0090197 |
4 |
0.117
|
Mouse |
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.114
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.114
|
|
|
|
regulation of immunological synapse formation
|
GO:2000520 |
2 |
0.114
|
|
|
|
regulation of myeloid leukocyte mediated immunity
|
GO:0002886 |
25 |
0.112
|
|
|
|
positive regulation of macrophage activation
|
GO:0043032 |
10 |
0.112
|
Mouse |
|
|
regulation of phagocytosis
|
GO:0050764 |
33 |
0.110
|
|
|
|
dendritic cell chemotaxis
|
GO:0002407 |
7 |
0.110
|
|
|
|
positive regulation of tumor necrosis factor production
|
GO:0032760 |
30 |
0.108
|
|
|
|
detection of biotic stimulus
|
GO:0009595 |
10 |
0.107
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
50 |
0.106
|
|
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
52 |
0.106
|
Mouse |
|
|
positive regulation of hematopoietic stem cell migration
|
GO:2000473 |
1 |
0.105
|
|
|
|
toll like receptor signaling pathway
|
GO:0002224 |
38 |
0.105
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.104
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.104
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.103
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.102
|
|
|
|
positive regulation of neutrophil chemotaxis
|
GO:0090023 |
12 |
0.101
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.100
|
|
|
|
hematopoietic stem cell migration
|
GO:0035701 |
1 |
0.100
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.099
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.099
|
Mouse |
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.099
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
68 |
0.099
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.098
|
Mouse |
|
|
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001240 |
16 |
0.098
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.097
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.097
|
|
|
|
negative regulation of signal transduction in absence of ligand
|
GO:1901099 |
16 |
0.097
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.096
|
Mouse |
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.096
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.096
|
|
|
|
response to interleukin 18
|
GO:0070673 |
4 |
0.096
|
Mouse |
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.096
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.095
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.094
|
|
|
|
regulation of b cell mediated immunity
|
GO:0002712 |
37 |
0.094
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
68 |
0.094
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.093
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.093
|
Mouse |
|
|
negative regulation of chemokine production
|
GO:0032682 |
4 |
0.092
|
Mouse |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.092
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.091
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.091
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.091
|
Mouse |
|
|
t helper 1 type immune response
|
GO:0042088 |
25 |
0.090
|
Mouse |
|
|
modification of morphology or physiology of other organism
|
GO:0035821 |
18 |
0.090
|
|
|
|
regulation of immunoglobulin mediated immune response
|
GO:0002889 |
37 |
0.090
|
|
|
|
positive regulation of chemotaxis
|
GO:0050921 |
38 |
0.090
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.090
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.089
|
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.089
|
|
|
|
cd4 positive alpha beta t cell differentiation involved in immune response
|
GO:0002294 |
28 |
0.089
|
Mouse |
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
41 |
0.088
|
Mouse |
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
71 |
0.088
|
|
|
|
detection of stimulus
|
GO:0051606 |
84 |
0.088
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.088
|
Mouse |
|
|
cellular extravasation
|
GO:0045123 |
17 |
0.087
|
|
|
|
regulation of vascular endothelial growth factor production
|
GO:0010574 |
13 |
0.087
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.086
|
|
|
|
positive regulation of neutrophil mediated killing of symbiont cell
|
GO:0070961 |
1 |
0.086
|
|
|
|
regulation of natural killer cell mediated cytotoxicity
|
GO:0042269 |
19 |
0.086
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.085
|
|
|
|
regulation of acute inflammatory response
|
GO:0002673 |
27 |
0.085
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.084
|
Mouse |
|
|
positive regulation of phagocytosis
|
GO:0050766 |
26 |
0.084
|
|
|
|
negative regulation of leukocyte mediated immunity
|
GO:0002704 |
29 |
0.084
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.084
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.083
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.083
|
Mouse |
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.083
|
|
|
|
regulation of chemokine secretion
|
GO:0090196 |
4 |
0.082
|
Mouse |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.082
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.082
|
Mouse |
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.081
|
|
|
|
regulation of macrophage activation
|
GO:0043030 |
17 |
0.081
|
Mouse |
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.080
|
Mouse |
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.079
|
Mouse |
|
|
regulation of jun kinase activity
|
GO:0043506 |
40 |
0.079
|
|
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
61 |
0.078
|
|
|
|
positive regulation of myeloid leukocyte mediated immunity
|
GO:0002888 |
14 |
0.077
|
|
|
|
microglial cell activation
|
GO:0001774 |
3 |
0.077
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.077
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.077
|
Mouse |
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.076
|
Mouse |
|
|
regulation of phospholipase c activity
|
GO:1900274 |
3 |
0.076
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.076
|
|
|
|
positive regulation of behavior
|
GO:0048520 |
40 |
0.075
|
|
|
|
cell recognition
|
GO:0008037 |
83 |
0.075
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
81 |
0.075
|
|
|
|
regulation of symbiosis encompassing mutualism through parasitism
|
GO:0043903 |
52 |
0.074
|
|
|
|
negative thymic t cell selection
|
GO:0045060 |
12 |
0.074
|
|
|
|
leukocyte degranulation
|
GO:0043299 |
27 |
0.073
|
|
|
|
amino sugar catabolic process
|
GO:0046348 |
1 |
0.073
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.072
|
|
|
|
leukocyte homeostasis
|
GO:0001776 |
79 |
0.072
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.072
|
|
|
|
regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001239 |
26 |
0.071
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
40 |
0.071
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.071
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.071
|
Mouse |
|
|
regulation of acute inflammatory response to non antigenic stimulus
|
GO:0002877 |
2 |
0.070
|
|
|
|
anion transport
|
GO:0006820 |
177 |
0.070
|
|
|
|
negative regulation of interferon gamma production
|
GO:0032689 |
18 |
0.070
|
Mouse |
|
|
t helper 2 cell cytokine production
|
GO:0035745 |
4 |
0.070
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.069
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.069
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.069
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.069
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
51 |
0.068
|
|
|
|
regulation of granulocyte chemotaxis
|
GO:0071622 |
17 |
0.068
|
|
|
|
detection of external biotic stimulus
|
GO:0098581 |
9 |
0.068
|
|
|
|
positive regulation of antigen receptor mediated signaling pathway
|
GO:0050857 |
9 |
0.067
|
|
|
|
t helper cell differentiation
|
GO:0042093 |
28 |
0.067
|
Mouse |
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.066
|
|
|
|
regulation of blood pressure
|
GO:0008217 |
93 |
0.066
|
|
|
|
antibacterial peptide secretion
|
GO:0002779 |
1 |
0.066
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.066
|
|
|
|
type 2 immune response
|
GO:0042092 |
23 |
0.066
|
|
|
|
positive regulation of immune complex clearance by monocytes and macrophages
|
GO:0090265 |
2 |
0.065
|
|
|
|
t cell differentiation involved in immune response
|
GO:0002292 |
30 |
0.065
|
Mouse |
|
|
alpha beta t cell differentiation involved in immune response
|
GO:0002293 |
30 |
0.064
|
Mouse |
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.064
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.064
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.064
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
61 |
0.064
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.064
|
|
|
|
bone resorption
|
GO:0045453 |
38 |
0.063
|
|
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
41 |
0.063
|
Mouse |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.063
|
|
|
|
positive regulation of alpha beta t cell activation
|
GO:0046635 |
39 |
0.063
|
|
|
|
antibacterial peptide production
|
GO:0002778 |
2 |
0.062
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.061
|
Mouse |
|
|
regulation of cell projection assembly
|
GO:0060491 |
38 |
0.061
|
|
|
|
regulation of angiotensin levels in blood
|
GO:0002002 |
4 |
0.059
|
|
|
|
regulation of hematopoietic stem cell migration
|
GO:2000471 |
1 |
0.059
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.059
|
|
|
|
cd4 positive alpha beta t cell cytokine production
|
GO:0035743 |
4 |
0.058
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.058
|
|
|
|
negative regulation of chemokine biosynthetic process
|
GO:0045079 |
2 |
0.058
|
Mouse |
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.058
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.058
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
64 |
0.058
|
|
|
|
regulation of neutrophil mediated killing of bacterium
|
GO:0070950 |
1 |
0.058
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.057
|
|
|
|
toll like receptor 7 signaling pathway
|
GO:0034154 |
4 |
0.057
|
|
|
|
myeloid cell apoptotic process
|
GO:0033028 |
22 |
0.057
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.057
|
|
|
|
macrophage chemotaxis
|
GO:0048246 |
14 |
0.057
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.057
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.056
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.056
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.056
|
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.055
|
|
|
|
t cell costimulation
|
GO:0031295 |
14 |
0.055
|
|
|
|
regulation of immune complex clearance by monocytes and macrophages
|
GO:0090264 |
2 |
0.055
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
11 |
0.055
|
|
|
|
regulation of type 2 immune response
|
GO:0002828 |
18 |
0.055
|
|
|
|
protein import
|
GO:0017038 |
101 |
0.055
|
Mouse |
|
|
regulation of neutrophil chemotaxis
|
GO:0090022 |
14 |
0.055
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.054
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.054
|
|
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.054
|
Mouse |
|
|
positive regulation of protein secretion
|
GO:0050714 |
52 |
0.054
|
Mouse |
|
|
positive regulation of granulocyte chemotaxis
|
GO:0071624 |
12 |
0.053
|
|
|
|
bone morphogenesis
|
GO:0060349 |
78 |
0.053
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.052
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.052
|
|
|
|
regulation of mast cell activation
|
GO:0033003 |
21 |
0.052
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.051
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.051
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.050
|
|
|
|
muscle contraction
|
GO:0006936 |
101 |
0.050
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.050
|
Mouse |
|
|
regulation of immunoglobulin production
|
GO:0002637 |
42 |
0.049
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.049
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.049
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.049
|
Mouse |
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.048
|
|
|
|
regulation of inflammatory response to antigenic stimulus
|
GO:0002861 |
21 |
0.048
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.048
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.048
|
|
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
42 |
0.047
|
|
|
|
regulation of toll like receptor 4 signaling pathway
|
GO:0034143 |
4 |
0.047
|
|
|
|
interleukin 1 secretion
|
GO:0050701 |
16 |
0.047
|
|
|
|
regulation of chemokine biosynthetic process
|
GO:0045073 |
8 |
0.047
|
Mouse |
|
|
myeloid cell activation involved in immune response
|
GO:0002275 |
34 |
0.047
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.046
|
Mouse |
|
|
renal system development
|
GO:0072001 |
225 |
0.046
|
|
|
|
eosinophil migration
|
GO:0072677 |
3 |
0.046
|
|
|
|
positive regulation of interleukin 6 production
|
GO:0032755 |
37 |
0.046
|
Mouse |
|
|
gliogenesis
|
GO:0042063 |
141 |
0.045
|
|
|
|
mast cell activation
|
GO:0045576 |
27 |
0.045
|
|
|
|
regulation of hematopoietic stem cell proliferation
|
GO:1902033 |
3 |
0.045
|
|
|
|
antibacterial peptide biosynthetic process
|
GO:0002780 |
2 |
0.045
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.045
|
|
|
|
positive regulation of interleukin 12 production
|
GO:0032735 |
21 |
0.045
|
|
|
|
vascular endothelial growth factor production
|
GO:0010573 |
13 |
0.045
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
56 |
0.045
|
|
|
|
alpha beta t cell proliferation
|
GO:0046633 |
21 |
0.045
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.044
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
69 |
0.044
|
|
|
|
regulation of eosinophil migration
|
GO:2000416 |
2 |
0.044
|
|
|
|
b cell activation involved in immune response
|
GO:0002312 |
50 |
0.044
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.044
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.044
|
|
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
83 |
0.044
|
|
|
|
positive regulation of glial cell differentiation
|
GO:0045687 |
21 |
0.044
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.044
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.044
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.043
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.043
|
|
|
|
regulation of angiotensin metabolic process
|
GO:0060177 |
4 |
0.043
|
|
|
|
negative regulation of lipopolysaccharide mediated signaling pathway
|
GO:0031665 |
3 |
0.042
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
50 |
0.042
|
|
|
|
positive regulation of inflammatory response to antigenic stimulus
|
GO:0002863 |
11 |
0.042
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.042
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.042
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.041
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.041
|
|
|
|
neuron migration
|
GO:0001764 |
122 |
0.041
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.041
|
|
|
|
positive regulation of alpha beta t cell proliferation
|
GO:0046641 |
12 |
0.040
|
|
|
|
positive regulation of t helper 1 cell differentiation
|
GO:0045627 |
4 |
0.040
|
|
|
|
positive regulation of neutrophil mediated cytotoxicity
|
GO:0070960 |
1 |
0.040
|
|
|
|
regulation of t helper 2 cell cytokine production
|
GO:2000551 |
3 |
0.040
|
|
|
|
extracellular structure organization
|
GO:0043062 |
148 |
0.040
|
|
|
|
positive regulation of b cell mediated immunity
|
GO:0002714 |
26 |
0.040
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.040
|
|
|
|
positive regulation of phospholipase c activity
|
GO:0010863 |
2 |
0.039
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.039
|
|
|
|
positive regulation of myeloid leukocyte differentiation
|
GO:0002763 |
26 |
0.039
|
|
|
|
neutrophil mediated killing of gram negative bacterium
|
GO:0070945 |
4 |
0.039
|
|
|
|
alpha beta t cell activation involved in immune response
|
GO:0002287 |
31 |
0.039
|
Mouse |
|
|
microglia development
|
GO:0014005 |
2 |
0.039
|
|
|
|
regulation of immunoglobulin production in mucosal tissue
|
GO:2000557 |
1 |
0.039
|
|
|
|
interleukin 12 production
|
GO:0032615 |
32 |
0.039
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.039
|
Mouse |
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.038
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.038
|
|
|
|
microglia differentiation
|
GO:0014004 |
2 |
0.038
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.037
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.037
|
|
|
|
leukocyte cell cell adhesion
|
GO:0007159 |
14 |
0.037
|
|
|
|
positive regulation of myotube differentiation
|
GO:0010831 |
24 |
0.037
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.037
|
|
|
|
positive regulation of b cell chemotaxis
|
GO:2000538 |
2 |
0.037
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.037
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.037
|
|
|
|
negative regulation of toll like receptor 2 signaling pathway
|
GO:0034136 |
3 |
0.037
|
|
|
|
peptide secretion
|
GO:0002790 |
114 |
0.037
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.037
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
95 |
0.037
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.036
|
|
|
|
regulation of interleukin 8 production
|
GO:0032677 |
3 |
0.036
|
|
|
|
regulation of t cell receptor signaling pathway
|
GO:0050856 |
21 |
0.036
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.036
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.036
|
|
|
|
negative regulation of serotonin secretion
|
GO:0014063 |
2 |
0.036
|
|
|
|
negative regulation of myeloid leukocyte differentiation
|
GO:0002762 |
20 |
0.036
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.035
|
|
|
|
positive regulation of t helper 2 cell cytokine production
|
GO:2000553 |
3 |
0.035
|
|
|
|
tumor necrosis factor biosynthetic process
|
GO:0042533 |
10 |
0.035
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.035
|
|
|
|
cellularization
|
GO:0007349 |
1 |
0.035
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.035
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.035
|
|
|
|
positive regulation of camp mediated signaling
|
GO:0043950 |
3 |
0.034
|
|
|
|
t cell migration
|
GO:0072678 |
19 |
0.034
|
|
|
|
regulation of interleukin 2 production
|
GO:0032663 |
28 |
0.034
|
|
|
|
positive regulation of dendritic cell dendrite assembly
|
GO:2000549 |
1 |
0.034
|
|
|
|
macrophage activation
|
GO:0042116 |
27 |
0.034
|
Mouse |
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.034
|
|
|
|
telencephalon cell migration
|
GO:0022029 |
55 |
0.034
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.034
|
|
|
|
transcription factor import into nucleus
|
GO:0042991 |
26 |
0.034
|
Mouse |
|
|
regulation of endothelial cell proliferation
|
GO:0001936 |
23 |
0.034
|
|
|
|
macrophage differentiation
|
GO:0030225 |
20 |
0.034
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.034
|
|
|
|
response to sterol
|
GO:0036314 |
4 |
0.033
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.033
|
|
|
|
regulation of interleukin 6 production
|
GO:0032675 |
55 |
0.033
|
Mouse |
|
|
positive regulation of natural killer cell chemotaxis
|
GO:2000503 |
1 |
0.033
|
|
|
|
regulated secretory pathway
|
GO:0045055 |
32 |
0.033
|
|
|
|
positive regulation of thymocyte migration
|
GO:2000412 |
2 |
0.033
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.033
|
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
50 |
0.033
|
|
|
|
lymphocyte migration
|
GO:0072676 |
26 |
0.033
|
|
