Mus musculus

0 known processes

Il1r2

interleukin 1 receptor, type II

(Aliases: Il1r-2,CD121b)

Il1r2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of response to wounding GO:1903034 189 0.781
Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.677
Mouse
defense response to other organism GO:0098542 197 0.655
cytokine production GO:0001816 319 0.652
Mouse
immune effector process GO:0002252 321 0.632
Mouse
cellular response to cytokine stimulus GO:0071345 189 0.607
Mouse
regulation of chemokine secretion GO:0090196 4 0.541
Mouse
inflammatory response GO:0006954 244 0.536
Mouse
regulation of inflammatory response GO:0050727 147 0.481
Mouse
t cell differentiation GO:0030217 174 0.449
Mouse
lymphocyte differentiation GO:0030098 242 0.436
Mouse
defense response to bacterium GO:0042742 119 0.418
t helper cell differentiation GO:0042093 28 0.405
Mouse
regulation of defense response GO:0031347 233 0.365
Mouse
regulation of cell activation GO:0050865 289 0.354
Mouse
alpha beta t cell activation GO:0046631 91 0.342
Mouse
t cell activation GO:0042110 289 0.338
Mouse
alpha beta t cell activation involved in immune response GO:0002287 31 0.327
Mouse
regulation of lymphocyte activation GO:0051249 240 0.326
Mouse
regulation of cytokine production GO:0001817 266 0.326
Mouse
lymphocyte mediated immunity GO:0002449 139 0.310
regulation of secretion by cell GO:1903530 249 0.307
Mouse
regulation of lymphocyte differentiation GO:0045619 107 0.298
Mouse
response to molecule of bacterial origin GO:0002237 143 0.297
leukocyte activation involved in immune response GO:0002366 126 0.269
Mouse
regulation of protein transport GO:0051223 163 0.261
Mouse
positive regulation of leukocyte differentiation GO:1902107 86 0.259
Mouse
regulation of protein localization GO:0032880 231 0.252
Mouse
leukocyte differentiation GO:0002521 342 0.241
Mouse
positive regulation of chemokine secretion GO:0090197 4 0.240
Mouse
regulation of t cell activation GO:0050863 170 0.236
Mouse
production of molecular mediator of immune response GO:0002440 103 0.231
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 28 0.224
Mouse
chemotaxis GO:0006935 247 0.222
disruption by host of symbiont cells GO:0051852 11 0.222
cytokine secretion GO:0050663 72 0.221
Mouse
positive regulation of inflammatory response GO:0050729 47 0.217
Mouse
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.212
Mouse
negative regulation of lymphocyte activation GO:0051250 91 0.207
positive regulation of lymphocyte activation GO:0051251 140 0.206
Mouse
negative regulation of cell activation GO:0050866 111 0.205
positive regulation of immune effector process GO:0002699 107 0.201
leukocyte migration GO:0050900 124 0.194
i kappab kinase nf kappab signaling GO:0007249 85 0.184
Mouse
cell activation involved in immune response GO:0002263 126 0.180
Mouse
neutrophil mediated killing of gram negative bacterium GO:0070945 4 0.176
regulation of cytokine secretion GO:0050707 61 0.173
Mouse
regulation of interferon gamma production GO:0032649 57 0.173
Mouse
protein secretion GO:0009306 111 0.172
Mouse
regulation of leukocyte mediated immunity GO:0002703 104 0.166
lymphocyte activation involved in immune response GO:0002285 93 0.158
Mouse
regulation of t cell differentiation GO:0045580 83 0.157
Mouse
negative regulation of cytokine production GO:0001818 84 0.154
Mouse
cytokine mediated signaling pathway GO:0019221 115 0.151
Mouse
negative regulation of protein metabolic process GO:0051248 282 0.147
Mouse
regulation of secretion GO:0051046 274 0.144
Mouse
response to lipopolysaccharide GO:0032496 128 0.144
regulation of adaptive immune response GO:0002819 90 0.140
Mouse
cell chemotaxis GO:0060326 81 0.140
cation homeostasis GO:0055080 212 0.139
positive regulation of cytokine production GO:0001819 174 0.137
Mouse
antibacterial peptide biosynthetic process GO:0002780 2 0.135
positive regulation of t cell differentiation GO:0045582 52 0.132
Mouse
calcium ion transport GO:0006816 159 0.130
regulation of cytokine biosynthetic process GO:0042035 59 0.130
Mouse
interleukin 18 mediated signaling pathway GO:0035655 2 0.129
Mouse
adaptive immune response GO:0002250 155 0.128
Mouse
divalent inorganic cation homeostasis GO:0072507 138 0.127
protein localization to organelle GO:0033365 185 0.123
Mouse
positive regulation of programmed cell death GO:0043068 218 0.121
negative regulation of multi organism process GO:0043901 68 0.119
regulation of innate immune response GO:0045088 91 0.117
positive regulation of apoptotic process GO:0043065 217 0.115
positive regulation of neutrophil mediated killing of symbiont cell GO:0070961 1 0.114
positive regulation of defense response GO:0031349 124 0.112
Mouse
negative regulation of lipopolysaccharide mediated signaling pathway GO:0031665 3 0.111
cd4 positive alpha beta t cell activation GO:0035710 45 0.111
Mouse
carbohydrate metabolic process GO:0005975 230 0.108
regulation of chemokine production GO:0032642 30 0.108
Mouse
regulation of establishment of protein localization GO:0070201 181 0.107
Mouse
apoptotic signaling pathway GO:0097190 306 0.107
regulation of intracellular transport GO:0032386 159 0.106
Mouse
cell adhesion GO:0007155 329 0.105
metal ion homeostasis GO:0055065 189 0.104
positive regulation of macrophage activation GO:0043032 10 0.104
Mouse
regulation of leukocyte differentiation GO:1902105 159 0.104
Mouse
natural killer cell activation GO:0030101 44 0.103
Mouse
positive regulation of protein modification process GO:0031401 299 0.102
cellular amino acid metabolic process GO:0006520 103 0.101
leukocyte mediated immunity GO:0002443 174 0.101
positive regulation of protein phosphorylation GO:0001934 242 0.100
negative regulation of t helper 1 type immune response GO:0002826 5 0.099
Mouse
positive regulation of t cell activation GO:0050870 101 0.099
Mouse
cell type specific apoptotic process GO:0097285 268 0.098
response to organonitrogen compound GO:0010243 246 0.097
eosinophil migration GO:0072677 3 0.095
positive regulation of cell death GO:0010942 224 0.094
regulation of cellular amino acid metabolic process GO:0006521 5 0.089
disruption of cells of other organism involved in symbiotic interaction GO:0051818 13 0.089
negative regulation of t cell activation GO:0050868 65 0.086
t cell differentiation involved in immune response GO:0002292 30 0.086
Mouse
thymocyte migration GO:0072679 2 0.085
regulation of cytoplasmic transport GO:1903649 112 0.085
Mouse
keratinocyte migration GO:0051546 3 0.085
response to extracellular stimulus GO:0009991 127 0.084
positive regulation of t cell proliferation GO:0042102 52 0.084
neutrophil mediated cytotoxicity GO:0070942 8 0.084
positive regulation of cellular amine metabolic process GO:0033240 5 0.083
muscle contraction GO:0006936 101 0.083
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.083
Mouse
peptide transport GO:0015833 133 0.083
Mouse
innate immune response GO:0045087 157 0.081
gland development GO:0048732 330 0.081
t cell proliferation GO:0042098 120 0.079
regulation of eosinophil migration GO:2000416 2 0.079
interferon gamma production GO:0032609 67 0.079
Mouse
activation of innate immune response GO:0002218 56 0.079
alpha beta t cell differentiation GO:0046632 69 0.078
Mouse
t helper 1 cell differentiation GO:0045063 13 0.078
Mouse
positive regulation of cell activation GO:0050867 158 0.078
Mouse
amide transport GO:0042886 138 0.077
Mouse
t cell activation involved in immune response GO:0002286 43 0.077
Mouse
positive regulation of secretion by cell GO:1903532 114 0.076
Mouse
interleukin 12 secretion GO:0072610 3 0.076
positive regulation of natural killer cell chemotaxis GO:2000503 1 0.075
nitrogen compound transport GO:0071705 271 0.075
Mouse
cellular response to biotic stimulus GO:0071216 92 0.074
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.074
response to protozoan GO:0001562 28 0.074
regulation of multi organism process GO:0043900 111 0.074
regulation of leukocyte proliferation GO:0070663 121 0.074
regulation of phospholipase c activity GO:1900274 3 0.073
positive regulation of transferase activity GO:0051347 167 0.073
acute inflammatory response GO:0002526 41 0.072
Mouse
positive regulation of leukocyte mediated immunity GO:0002705 70 0.072
response to peptide GO:1901652 136 0.072
protein targeting GO:0006605 143 0.071
Mouse
leukocyte mediated cytotoxicity GO:0001909 62 0.071
positive regulation of t helper 1 cell differentiation GO:0045627 4 0.071
neutrophil mediated killing of gram positive bacterium GO:0070946 2 0.071
cellular response to acid chemical GO:0071229 68 0.071
alpha beta t cell differentiation involved in immune response GO:0002293 30 0.071
Mouse
regulation of neuron apoptotic process GO:0043523 122 0.069
myeloid leukocyte mediated immunity GO:0002444 42 0.069
cell killing GO:0001906 67 0.069
myeloid leukocyte migration GO:0097529 57 0.069
positive regulation of cytokine biosynthetic process GO:0042108 40 0.068
cellular ketone metabolic process GO:0042180 84 0.067
negative regulation of immune system process GO:0002683 209 0.067
Mouse
reactive oxygen species metabolic process GO:0072593 84 0.067
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.067
regulation of cell migration GO:0030334 219 0.066
protein import GO:0017038 101 0.065
Mouse
regulation of kinase activity GO:0043549 249 0.064
inflammatory response to wounding GO:0090594 4 0.064
cellular metal ion homeostasis GO:0006875 151 0.063
detection of fungus GO:0016046 2 0.063
regulation of alpha beta t cell activation GO:0046634 53 0.063
t helper 1 type immune response GO:0042088 25 0.062
Mouse
nuclear import GO:0051170 95 0.062
Mouse
protein processing GO:0016485 163 0.062
regulation of homeostatic process GO:0032844 182 0.062
b cell mediated immunity GO:0019724 71 0.061
antimicrobial peptide biosynthetic process GO:0002777 2 0.061
positive regulation of lymphocyte differentiation GO:0045621 61 0.061
Mouse
wound healing involved in inflammatory response GO:0002246 4 0.060
regulation of protein import into nucleus GO:0042306 52 0.060
Mouse
macromolecule catabolic process GO:0009057 281 0.060
cellular response to amino acid stimulus GO:0071230 29 0.059
negative regulation of leukocyte proliferation GO:0070664 46 0.059
killing of cells in other organism involved in symbiotic interaction GO:0051883 13 0.058
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.058
interleukin 33 mediated signaling pathway GO:0038172 1 0.058
Mouse
activation of immune response GO:0002253 138 0.058
positive regulation of type 2 immune response GO:0002830 9 0.058
positive regulation of innate immune response GO:0045089 80 0.057
cellular response to lipopolysaccharide GO:0071222 77 0.057
positive regulation of cd4 positive alpha beta t cell proliferation GO:2000563 1 0.056
cellular amine metabolic process GO:0044106 44 0.055
positive regulation of b cell chemotaxis GO:2000538 2 0.054
leukocyte apoptotic process GO:0071887 71 0.054
phagocytosis GO:0006909 66 0.053
intracellular protein transport GO:0006886 204 0.053
Mouse
cellular lipid metabolic process GO:0044255 323 0.053
divalent metal ion transport GO:0070838 172 0.052
regulation of hormone levels GO:0010817 211 0.052
regulation of t cell proliferation GO:0042129 92 0.051
cytokine biosynthetic process GO:0042089 68 0.051
Mouse
myeloid leukocyte differentiation GO:0002573 119 0.051
regulation of apoptotic signaling pathway GO:2001233 197 0.051
leukocyte homeostasis GO:0001776 79 0.051
regulation of natural killer cell chemotaxis GO:2000501 1 0.051
regulation of transcription factor import into nucleus GO:0042990 24 0.050
Mouse
establishment of protein localization to organelle GO:0072594 118 0.050
Mouse
response to organic cyclic compound GO:0014070 198 0.050
antibacterial peptide secretion GO:0002779 1 0.050
negative regulation of cell proliferation GO:0008285 296 0.050
nuclear transport GO:0051169 139 0.049
Mouse
positive regulation of lymphocyte proliferation GO:0050671 70 0.049
negative regulation of cellular protein metabolic process GO:0032269 247 0.049
response to oxidative stress GO:0006979 123 0.048
killing by host of symbiont cells GO:0051873 11 0.048
epithelial tube morphogenesis GO:0060562 303 0.048
striated muscle tissue development GO:0014706 293 0.047
positive regulation of monocyte chemotaxis GO:0090026 2 0.047
placenta development GO:0001890 140 0.047
lymphocyte proliferation GO:0046651 164 0.047
activation of mapk activity involved in innate immune response GO:0035419 2 0.047
regulation of hydrolase activity GO:0051336 246 0.047
single organism cell adhesion GO:0098602 156 0.047
regulation of protein targeting GO:1903533 61 0.046
Mouse
amine metabolic process GO:0009308 45 0.046
regulation of cellular ketone metabolic process GO:0010565 66 0.046
positive regulation of interferon gamma production GO:0032729 39 0.046
Mouse
antimicrobial peptide production GO:0002775 2 0.045
circulatory system process GO:0003013 197 0.045
positive regulation of immunoglobulin production in mucosal tissue GO:2000558 1 0.045
regulation of transferase activity GO:0051338 263 0.045
response to peptide hormone GO:0043434 127 0.045
calcium ion homeostasis GO:0055074 127 0.045
neutrophil mediated killing of symbiont cell GO:0070943 8 0.044
regulation of protein secretion GO:0050708 82 0.044
Mouse
cellular response to lipid GO:0071396 145 0.044
leukocyte proliferation GO:0070661 172 0.044
positive regulation of angiogenesis GO:0045766 46 0.044
regulation of neutrophil mediated killing of gram negative bacterium GO:0070951 1 0.043
peptide secretion GO:0002790 114 0.043
cytokine metabolic process GO:0042107 71 0.042
Mouse
positive regulation of response to wounding GO:1903036 66 0.042
Mouse
positive regulation of protein kinase activity GO:0045860 144 0.042
humoral immune response GO:0006959 57 0.042
cellular calcium ion homeostasis GO:0006874 119 0.042
regulation of cd4 positive alpha beta t cell activation GO:2000514 24 0.042
response to insulin GO:0032868 100 0.042
cellular response to dna damage stimulus GO:0006974 207 0.042
chemokine secretion GO:0090195 5 0.042
Mouse
regulation of cd8 positive alpha beta t cell extravasation GO:2000449 3 0.042
cell recognition GO:0008037 83 0.041
fat cell differentiation GO:0045444 160 0.041
regulation of immunoglobulin mediated immune response GO:0002889 37 0.041
positive regulation of protein transport GO:0051222 93 0.041
Mouse
immunoglobulin mediated immune response GO:0016064 69 0.041
response to radiation GO:0009314 165 0.041
neuron death GO:0070997 154 0.041
peptidyl amino acid modification GO:0018193 336 0.041
cytoplasmic transport GO:0016482 234 0.041
Mouse
positive regulation of interleukin 6 production GO:0032755 37 0.041
Mouse
positive regulation of alpha beta t cell activation GO:0046635 39 0.040
regulation of cell motility GO:2000145 236 0.040
neutrophil mediated killing of bacterium GO:0070944 6 0.040
transcription factor import into nucleus GO:0042991 26 0.040
Mouse
cellular response to organonitrogen compound GO:0071417 145 0.040
regulation of immunoglobulin production in mucosal tissue GO:2000557 1 0.039
regulation of cellular response to stress GO:0080135 159 0.039
epithelial cell proliferation GO:0050673 174 0.038
regulation of reactive oxygen species metabolic process GO:2000377 40 0.038
endocytosis GO:0006897 168 0.038
astrocyte cell migration GO:0043615 3 0.038
microglial cell activation involved in immune response GO:0002282 1 0.038
muscle cell differentiation GO:0042692 261 0.037
peptide metabolic process GO:0006518 46 0.037
t helper 1 cell cytokine production GO:0035744 1 0.037
interleukin 2 biosynthetic process GO:0042094 15 0.037
Mouse
neutrophil mediated immunity GO:0002446 19 0.037
granzyme mediated apoptotic signaling pathway GO:0008626 1 0.037
regulation of t helper 1 cell cytokine production GO:2000554 1 0.037
homeostasis of number of cells GO:0048872 210 0.037
regulation of alpha beta t cell differentiation GO:0046637 35 0.037
skeletal system development GO:0001501 356 0.036
positive regulation of cell development GO:0010720 237 0.036
positive regulation of dendritic cell dendrite assembly GO:2000549 1 0.036
muscle tissue development GO:0060537 308 0.036
regulation of thymocyte migration GO:2000410 2 0.036
sequestering of metal ion GO:0051238 19 0.036
stimulatory c type lectin receptor signaling pathway GO:0002223 2 0.035
negative regulation of chemokine production GO:0032682 4 0.035
Mouse
regulation of t helper 1 cell differentiation GO:0045625 7 0.035
interspecies interaction between organisms GO:0044419 83 0.035
negative regulation of apoptotic signaling pathway GO:2001234 104 0.034
regulation of proteolysis GO:0030162 164 0.034
ossification GO:0001503 216 0.034
regulation of interleukin 4 biosynthetic process GO:0045402 3 0.034
negative regulation of t helper 1 cell differentiation GO:0045626 3 0.034
germinal center formation GO:0002467 16 0.034
neuron apoptotic process GO:0051402 142 0.034
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.034
response to reactive oxygen species GO:0000302 56 0.034
cellular chemical homeostasis GO:0055082 215 0.034
negative regulation of leukocyte differentiation GO:1902106 51 0.034
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.033
t helper 2 cell differentiation GO:0045064 12 0.033
type 2 immune response GO:0042092 23 0.033
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.033
regulation of nucleocytoplasmic transport GO:0046822 73 0.033
Mouse
regulation of protein serine threonine kinase activity GO:0071900 157 0.033
defense response to fungus GO:0050832 12 0.033
cellular response to interleukin 15 GO:0071350 2 0.033
negative regulation of cytokine biosynthetic process GO:0042036 13 0.033
Mouse
cellular response to growth factor stimulus GO:0071363 197 0.033
negative regulation of phosphorus metabolic process GO:0010563 184 0.033
defense response to gram negative bacterium GO:0050829 28 0.033
antibacterial peptide production GO:0002778 2 0.032
regulation of fat cell differentiation GO:0045598 81 0.032
response to nutrient levels GO:0031667 109 0.032
regulation of organelle organization GO:0033043 289 0.032
positive regulation of secretion GO:0051047 130 0.032
Mouse
regulation of syncytium formation by plasma membrane fusion GO:0060142 23 0.032
innate immune response activating signal transduction GO:0002758 50 0.032
dna recombination GO:0006310 92 0.032
cellular response to hormone stimulus GO:0032870 150 0.032
lymphocyte migration GO:0072676 26 0.032
interaction with symbiont GO:0051702 14 0.032
regulation of tumor necrosis factor production GO:0032680 49 0.031
negative regulation of inflammatory response GO:0050728 61 0.031
acute phase response GO:0006953 10 0.031
Mouse
response to acid chemical GO:0001101 111 0.031
hexose metabolic process GO:0019318 98 0.031
cell cycle g1 s phase transition GO:0044843 57 0.031
intrinsic apoptotic signaling pathway GO:0097193 132 0.031
positive regulation of thymocyte migration GO:2000412 2 0.030
carbohydrate derivative biosynthetic process GO:1901137 183 0.030
positive regulation of cell projection organization GO:0031346 95 0.030
chemokine production GO:0032602 34 0.030
Mouse
immune response activating signal transduction GO:0002757 116 0.030
leukocyte migration involved in inflammatory response GO:0002523 7 0.030
regulation of immunoglobulin production GO:0002637 42 0.030
nonribosomal peptide biosynthetic process GO:0019184 5 0.030
regulation of peptide transport GO:0090087 91 0.030
Mouse
cellular response to peptide GO:1901653 92 0.030
germ cell development GO:0007281 185 0.030
negative regulation of t cell proliferation GO:0042130 38 0.030
nucleotide metabolic process GO:0009117 332 0.029
negative regulation of intracellular signal transduction GO:1902532 167 0.029
Mouse
engulfment of apoptotic cell GO:0043652 3 0.029
regulation of membrane potential GO:0042391 192 0.029
protein maturation GO:0051604 176 0.029
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 0.029
Mouse
regulation of cd4 positive alpha beta t cell proliferation GO:2000561 2 0.029
regulation of endopeptidase activity GO:0052548 89 0.029
regulation of leukocyte apoptotic process GO:2000106 56 0.029
divalent inorganic cation transport GO:0072511 178 0.029
skeletal muscle organ development GO:0060538 163 0.028
small gtpase mediated signal transduction GO:0007264 97 0.028
g protein coupled receptor signaling pathway GO:0007186 243 0.028
positive regulation of t helper 1 cell cytokine production GO:2000556 1 0.028
regulation of production of molecular mediator of immune response GO:0002700 65 0.027
regulation of interleukin 6 production GO:0032675 55 0.027
Mouse
positive regulation of protein secretion GO:0050714 52 0.027
Mouse
detection of stimulus GO:0051606 84 0.027
regulation of ion transport GO:0043269 215 0.027
regulation of lymphocyte apoptotic process GO:0070228 41 0.027
antibacterial humoral response GO:0019731 8 0.027
cellular divalent inorganic cation homeostasis GO:0072503 127 0.027
negative regulation of defense response GO:0031348 77 0.027
posttranscriptional regulation of gene expression GO:0010608 155 0.027
regulation of cellular amine metabolic process GO:0033238 20 0.027
blood vessel morphogenesis GO:0048514 285 0.027
modification of morphology or physiology of other organism GO:0035821 18 0.027
negative regulation of cell migration GO:0030336 59 0.027
organic anion transport GO:0015711 137 0.027
positive regulation of alpha beta t cell differentiation GO:0046638 28 0.027
cellular homeostasis GO:0019725 240 0.027
extracellular matrix organization GO:0030198 147 0.027
regulation of defense response to fungus GO:1900150 1 0.027
regulation of acute inflammatory response GO:0002673 27 0.027
eosinophil activation involved in immune response GO:0002278 1 0.027
positive regulation of nucleocytoplasmic transport GO:0046824 30 0.027
Mouse
sensory organ morphogenesis GO:0090596 242 0.026
regulation of exocytosis GO:0017157 61 0.026
positive regulation of production of molecular mediator of immune response GO:0002702 45 0.026
fatty acid metabolic process GO:0006631 121 0.026
positive regulation of membrane protein ectodomain proteolysis GO:0051044 3 0.026
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.026
response to steroid hormone GO:0048545 56 0.026
sequestering of calcium ion GO:0051208 18 0.026
reactive nitrogen species metabolic process GO:2001057 0 0.026
regulation of vesicle mediated transport GO:0060627 139 0.026
immunoglobulin production GO:0002377 73 0.026
chromatin modification GO:0016568 187 0.026
neutrophil mediated killing of fungus GO:0070947 3 0.025
positive regulation of myeloid leukocyte mediated immunity GO:0002888 14 0.025
negative regulation of secretion GO:0051048 61 0.025
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.025
regulation of peptidase activity GO:0052547 96 0.025
regulation of myotube differentiation GO:0010830 62 0.025
cell substrate adhesion GO:0031589 130 0.025
natural killer cell mediated immunity GO:0002228 29 0.025
protein catabolic process GO:0030163 221 0.025
positive regulation of neutrophil mediated cytotoxicity GO:0070960 1 0.025
cd4 positive alpha beta t cell proliferation GO:0035739 2 0.025
granulocyte migration GO:0097530 43 0.025
cytosolic calcium ion transport GO:0060401 48 0.025
regulation of lymphocyte proliferation GO:0050670 117 0.025
peptide biosynthetic process GO:0043043 11 0.025
positive regulation of intracellular transport GO:0032388 70 0.025
Mouse
interleukin 8 production GO:0032637 4 0.025
negative regulation of protein processing GO:0010955 79 0.025
multi multicellular organism process GO:0044706 109 0.025
regulation of muscle tissue development GO:1901861 97 0.024
cellular response to extracellular stimulus GO:0031668 81 0.024
syncytium formation by plasma membrane fusion GO:0000768 42 0.024
t helper 17 cell lineage commitment GO:0072540 4 0.024
regulation of cell adhesion GO:0030155 154 0.024
neutrophil apoptotic process GO:0001781 3 0.024
myeloid cell differentiation GO:0030099 233 0.024
glucose metabolic process GO:0006006 92 0.023
oxidation reduction process GO:0055114 342 0.023
neutrophil migration GO:1990266 37 0.023
regulation of chemokine biosynthetic process GO:0045073 8 0.023
Mouse
regulation of t helper cell differentiation GO:0045622 14 0.023
protein import into nucleus GO:0006606 95 0.023
Mouse
negative regulation of lymphocyte proliferation GO:0050672 45 0.023
cellular ion homeostasis GO:0006873 165 0.023
regulation of intracellular protein transport GO:0033157 82 0.023
Mouse
negative regulation of response to wounding GO:1903035 77 0.023
regulation of myeloid leukocyte mediated immunity GO:0002886 25 0.023
response to drug GO:0042493 75 0.023
mature dendritic cell differentiation GO:0097029 3 0.023
regulation of growth of symbiont in host GO:0044126 19 0.023
t helper 2 cell cytokine production GO:0035745 4 0.023
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.023
positive regulation of protein localization to nucleus GO:1900182 30 0.023
Mouse
regulation of myoblast differentiation GO:0045661 29 0.022
immune response regulating signaling pathway GO:0002764 125 0.022
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.022
interleukin 2 production GO:0032623 33 0.022
Mouse
regulation of neutrophil mediated killing of symbiont cell GO:0070949 2 0.022
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.022
positive regulation of eosinophil migration GO:2000418 2 0.022
lymphocyte homeostasis GO:0002260 64 0.022
peptide hormone secretion GO:0030072 109 0.022
arachidonic acid metabolite production involved in inflammatory response GO:0002538 2 0.022
mature natural killer cell chemotaxis GO:0035782 1 0.022
negative regulation of macrophage chemotaxis GO:0010760 1 0.022
fatty acid biosynthetic process GO:0006633 41 0.022
monosaccharide metabolic process GO:0005996 106 0.022
positive regulation of leukocyte proliferation GO:0070665 73 0.022
myotube differentiation GO:0014902 105 0.022
cdc42 protein signal transduction GO:0032488 0 0.022
mapk cascade GO:0000165 281 0.022
regulation of lymphocyte mediated immunity GO:0002706 84 0.022
gliogenesis GO:0042063 141 0.022
positive regulation of intracellular protein transport GO:0090316 42 0.021
Mouse
lipid biosynthetic process GO:0008610 179 0.021
extracellular structure organization GO:0043062 148 0.021
antigen receptor mediated signaling pathway GO:0050851 64 0.021
negative regulation of chemokine biosynthetic process GO:0045079 2 0.021
Mouse
regulation of defense response to bacterium GO:1900424 3 0.021
detection of yeast GO:0001879 2 0.021
sensory perception GO:0007600 245 0.021
leukocyte chemotaxis GO:0030595 69 0.021
leukotriene production involved in inflammatory response GO:0002540 2 0.021
positive regulation of cytoplasmic transport GO:1903651 40 0.021
Mouse
transmission of nerve impulse GO:0019226 76 0.021
fatty acid derivative biosynthetic process GO:1901570 15 0.021
regulation of regulated secretory pathway GO:1903305 20 0.021
fertilization GO:0009566 127 0.021
cell cell recognition GO:0009988 44 0.021
purine containing compound metabolic process GO:0072521 311 0.020
nucleocytoplasmic transport GO:0006913 139 0.020
Mouse
regulation of insulin receptor signaling pathway GO:0046626 21 0.020
blood circulation GO:0008015 195 0.020
positive regulation of cell killing GO:0031343 33 0.020
response to inorganic substance GO:0010035 96 0.020
regulation of type 2 immune response GO:0002828 18 0.020
regulation of neuron differentiation GO:0045664 281 0.020
regulation of macrophage activation GO:0043030 17 0.020
Mouse
single organism nuclear import GO:1902593 95 0.020
Mouse
protein homotrimerization GO:0070207 4 0.020
negative regulation of growth of symbiont involved in interaction with host GO:0044146 19 0.020
regulation of reproductive process GO:2000241 66 0.020
angiogenesis GO:0001525 201 0.020
regulation of interleukin 8 production GO:0032677 3 0.020
antimicrobial peptide secretion GO:0002776 1 0.020
negative regulation of secretion by cell GO:1903531 54 0.020
negative regulation of lymphocyte differentiation GO:0045620 32 0.020
t cell mediated immunity GO:0002456 50 0.019
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.019
smooth muscle contraction GO:0006939 44 0.019
axonogenesis GO:0007409 274 0.019
negative regulation of interleukin 10 secretion GO:2001180 2 0.019
cation transport GO:0006812 399 0.019
second messenger mediated signaling GO:0019932 73 0.019
regulation of hematopoietic stem cell proliferation GO:1902033 3 0.019
cellular response to interleukin 18 GO:0071351 3 0.019
Mouse
regulation of t helper 2 cell cytokine production GO:2000551 3 0.019
response to transforming growth factor beta GO:0071559 88 0.019
negative regulation of molecular function GO:0044092 258 0.019
defense response to gram positive bacterium GO:0050830 50 0.019
regulation of protein processing GO:0070613 96 0.019

Il1r2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.047
disease of anatomical entity DOID:7 0 0.047
respiratory system disease DOID:1579 0 0.034
cancer DOID:162 0 0.032
disease of cellular proliferation DOID:14566 0 0.032
disease of metabolism DOID:0014667 0 0.029
lupus erythematosus DOID:8857 0 0.026
hypersensitivity reaction disease DOID:0060056 0 0.026
hypersensitivity reaction type ii disease DOID:417 0 0.026