Mus musculus

134 known processes

Il1rl1

interleukin 1 receptor-like 1

(Aliases: DER4,St2-rs1,T1,Fit-1,T1/ST2,St2,ST2L,Ly84)

Il1rl1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of chemokine secretion GO:0090196 4 0.951
regulation of macrophage activation GO:0043030 17 0.945
regulation of chemokine production GO:0032642 30 0.913
positive regulation of macrophage activation GO:0043032 10 0.913
positive regulation of defense response GO:0031349 124 0.874
positive regulation of inflammatory response GO:0050729 47 0.793
immune effector process GO:0002252 321 0.791
Mouse
cytokine secretion GO:0050663 72 0.768
cytokine production GO:0001816 319 0.764
positive regulation of chemokine secretion GO:0090197 4 0.763
positive regulation of cytokine production GO:0001819 174 0.740
regulation of defense response GO:0031347 233 0.724
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.723
adaptive immune response GO:0002250 155 0.713
chemokine production GO:0032602 34 0.628
positive regulation of response to wounding GO:1903036 66 0.621
positive regulation of cytokine secretion GO:0050715 41 0.600
positive regulation of protein secretion GO:0050714 52 0.571
negative regulation of interferon gamma production GO:0032689 18 0.567
inflammatory response GO:0006954 244 0.553
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.544
positive regulation of cell activation GO:0050867 158 0.473
myeloid leukocyte activation GO:0002274 83 0.447
regulation of inflammatory response GO:0050727 147 0.444
negative regulation of cytokine production GO:0001818 84 0.429
cellular response to cytokine stimulus GO:0071345 189 0.424
interferon gamma production GO:0032609 67 0.424
negative regulation of immune system process GO:0002683 209 0.423
regulation of interleukin 6 production GO:0032675 55 0.409
Mouse
regulation of interferon gamma production GO:0032649 57 0.390
regulation of adaptive immune response GO:0002819 90 0.383
positive regulation of immune effector process GO:0002699 107 0.369
regulation of cytokine production GO:0001817 266 0.363
positive regulation of interleukin 6 production GO:0032755 37 0.362
Mouse
interleukin 18 mediated signaling pathway GO:0035655 2 0.344
Mouse
positive regulation of monocyte chemotaxis GO:0090026 2 0.338
positive regulation of chemokine production GO:0032722 22 0.337
negative regulation of adaptive immune response GO:0002820 25 0.333
chemokine secretion GO:0090195 5 0.326
negative regulation of t helper 1 type immune response GO:0002826 5 0.321
regulation of protein secretion GO:0050708 82 0.316
leukocyte migration GO:0050900 124 0.315
defense response to other organism GO:0098542 197 0.314
cytokine metabolic process GO:0042107 71 0.300
Mouse
regulation of protein transport GO:0051223 163 0.297
apoptotic signaling pathway GO:0097190 306 0.287
cytokine biosynthetic process GO:0042089 68 0.280
Mouse
macrophage activation GO:0042116 27 0.277
regulation of leukocyte mediated immunity GO:0002703 104 0.265
regulation of response to wounding GO:1903034 189 0.259
regulation of establishment of protein localization GO:0070201 181 0.254
positive regulation of protein transport GO:0051222 93 0.243
regulation of cell activation GO:0050865 289 0.228
t helper cell differentiation GO:0042093 28 0.225
Mouse
regulation of t helper 1 type immune response GO:0002825 17 0.220
acute inflammatory response GO:0002526 41 0.219
Mouse
regulation of protein localization GO:0032880 231 0.218
defense response to virus GO:0051607 68 0.208
positive regulation of secretion by cell GO:1903532 114 0.203
positive regulation of production of molecular mediator of immune response GO:0002702 45 0.200
interleukin 5 production GO:0032634 10 0.199
regulation of cytokine secretion GO:0050707 61 0.198
leukocyte activation involved in immune response GO:0002366 126 0.198
Mouse
positive regulation of type 2 immune response GO:0002830 9 0.190
negative regulation of chemokine production GO:0032682 4 0.190
Mouse
regulation of secretion GO:0051046 274 0.185
leukocyte differentiation GO:0002521 342 0.183
Mouse
interleukin 33 mediated signaling pathway GO:0038172 1 0.181
response to molecule of bacterial origin GO:0002237 143 0.180
lymphocyte differentiation GO:0030098 242 0.178
Mouse
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 28 0.177
Mouse
regulation of t cell activation GO:0050863 170 0.173
Mouse
lymphocyte mediated immunity GO:0002449 139 0.171
positive regulation of secretion GO:0051047 130 0.164
neutrophil mediated killing of gram positive bacterium GO:0070946 2 0.162
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.161
negative regulation of secretion GO:0051048 61 0.152
cell activation involved in immune response GO:0002263 126 0.151
Mouse
regulation of lymphocyte activation GO:0051249 240 0.150
Mouse
circulatory system process GO:0003013 197 0.149
t cell mediated immunity GO:0002456 50 0.149
positive regulation of interleukin 5 production GO:0032754 5 0.145
immune response activating signal transduction GO:0002757 116 0.144
cellular response to interleukin 18 GO:0071351 3 0.144
Mouse
mature dendritic cell differentiation GO:0097029 3 0.143
t helper 1 type immune response GO:0042088 25 0.142
response to lipopolysaccharide GO:0032496 128 0.131
regulation of cell motility GO:2000145 236 0.131
positive regulation of t cell activation GO:0050870 101 0.128
Mouse
anion transport GO:0006820 177 0.128
regulation of monocyte chemotaxis GO:0090025 3 0.127
t cell activation GO:0042110 289 0.125
Mouse
organic acid transport GO:0015849 101 0.124
leukocyte apoptotic process GO:0071887 71 0.124
production of molecular mediator of immune response GO:0002440 103 0.121
regulation of angiotensin levels in blood GO:0002002 4 0.120
regulation of angiotensin metabolic process GO:0060177 4 0.118
regulation of leukocyte differentiation GO:1902105 159 0.117
Mouse
regulation of immunoglobulin production GO:0002637 42 0.116
macromolecule catabolic process GO:0009057 281 0.115
regulation of type 2 immune response GO:0002828 18 0.115
natural killer cell activation GO:0030101 44 0.114
Mouse
interspecies interaction between organisms GO:0044419 83 0.113
interleukin 12 secretion GO:0072610 3 0.113
cytokine mediated signaling pathway GO:0019221 115 0.112
type 2 immune response GO:0042092 23 0.111
defense response to bacterium GO:0042742 119 0.111
regulation of cytokine biosynthetic process GO:0042035 59 0.111
Mouse
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.110
Mouse
regulation of secretion by cell GO:1903530 249 0.106
granzyme mediated apoptotic signaling pathway GO:0008626 1 0.104
wound healing GO:0042060 157 0.104
disruption by host of symbiont cells GO:0051852 11 0.101
t cell extravasation GO:0072683 4 0.100
carbohydrate derivative biosynthetic process GO:1901137 183 0.100
leukocyte mediated immunity GO:0002443 174 0.098
myeloid leukocyte migration GO:0097529 57 0.097
positive regulation of lymphocyte activation GO:0051251 140 0.094
Mouse
negative regulation of immune effector process GO:0002698 55 0.094
alpha beta t cell activation involved in immune response GO:0002287 31 0.094
Mouse
negative regulation of secretion by cell GO:1903531 54 0.093
regulation of innate immune response GO:0045088 91 0.092
organic anion transport GO:0015711 137 0.089
granulocyte chemotaxis GO:0071621 39 0.088
t helper 2 cell cytokine production GO:0035745 4 0.088
lymphocyte activation involved in immune response GO:0002285 93 0.087
Mouse
positive regulation of lymphocyte proliferation GO:0050671 70 0.087
regulation of leukocyte proliferation GO:0070663 121 0.087
positive regulation of leukocyte differentiation GO:1902107 86 0.086
Mouse
cellular amino acid metabolic process GO:0006520 103 0.086
protein secretion GO:0009306 111 0.083
negative regulation of cell proliferation GO:0008285 296 0.083
Rat
regulation of homeostatic process GO:0032844 182 0.083
cytoplasmic transport GO:0016482 234 0.083
Mouse
t cell proliferation GO:0042098 120 0.083
regulation of chemokine biosynthetic process GO:0045073 8 0.082
Mouse
negative regulation of protein transport GO:0051224 46 0.081
detection of fungus GO:0016046 2 0.080
regulation of cellular catabolic process GO:0031329 242 0.079
interleukin 2 biosynthetic process GO:0042094 15 0.078
Mouse
regulation of tumor necrosis factor production GO:0032680 49 0.077
regulation of lymphocyte proliferation GO:0050670 117 0.077
sequestering of calcium ion GO:0051208 18 0.076
cell killing GO:0001906 67 0.075
amine metabolic process GO:0009308 45 0.075
regulation of reactive oxygen species metabolic process GO:2000377 40 0.074
interleukin 6 production GO:0032635 58 0.074
Mouse
regulation of transferase activity GO:0051338 263 0.073
positive regulation of protein phosphorylation GO:0001934 242 0.073
killing of cells in other organism involved in symbiotic interaction GO:0051883 13 0.073
myeloid leukocyte mediated immunity GO:0002444 42 0.073
myeloid leukocyte differentiation GO:0002573 119 0.073
interleukin 2 production GO:0032623 33 0.073
Mouse
cation homeostasis GO:0055080 212 0.072
eosinophil migration GO:0072677 3 0.071
nuclear transport GO:0051169 139 0.071
Mouse
regulation of leukocyte apoptotic process GO:2000106 56 0.070
leukocyte mediated cytotoxicity GO:0001909 62 0.069
divalent inorganic cation transport GO:0072511 178 0.069
organonitrogen compound biosynthetic process GO:1901566 192 0.069
acute phase response GO:0006953 10 0.068
Mouse
cell chemotaxis GO:0060326 81 0.068
blood vessel morphogenesis GO:0048514 285 0.068
regulation of acute inflammatory response GO:0002673 27 0.067
cellular amine metabolic process GO:0044106 44 0.067
stimulatory c type lectin receptor signaling pathway GO:0002223 2 0.067
negative regulation of intracellular signal transduction GO:1902532 167 0.066
intracellular protein transport GO:0006886 204 0.065
Mouse
positive regulation of eosinophil migration GO:2000418 2 0.065
lymphocyte proliferation GO:0046651 164 0.064
cell adhesion GO:0007155 329 0.063
eosinophil degranulation GO:0043308 1 0.063
cellular homeostasis GO:0019725 240 0.063
sequestering of metal ion GO:0051238 19 0.063
alpha beta t cell activation GO:0046631 91 0.062
Mouse
leukocyte chemotaxis GO:0030595 69 0.062
regulation of thymocyte migration GO:2000410 2 0.062
regulation of cellular amine metabolic process GO:0033238 20 0.061
defense response to gram positive bacterium GO:0050830 50 0.061
protein import into nucleus GO:0006606 95 0.061
Mouse
nucleocytoplasmic transport GO:0006913 139 0.060
Mouse
divalent metal ion transport GO:0070838 172 0.060
immunoglobulin production GO:0002377 73 0.059
extrinsic apoptotic signaling pathway GO:0097191 126 0.059
cation transport GO:0006812 399 0.058
granulocyte migration GO:0097530 43 0.058
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.058
g protein coupled receptor signaling pathway GO:0007186 243 0.058
positive regulation of t cell receptor signaling pathway GO:0050862 4 0.058
divalent inorganic cation homeostasis GO:0072507 138 0.058
positive regulation of leukocyte proliferation GO:0070665 73 0.058
response to organonitrogen compound GO:0010243 246 0.057
Rat
negative regulation of cell activation GO:0050866 111 0.057
positive regulation of immunological synapse formation GO:2000522 1 0.056
dendritic cell chemotaxis GO:0002407 7 0.056
regulation of t cell differentiation GO:0045580 83 0.056
Mouse
reactive oxygen species metabolic process GO:0072593 84 0.056
regulation of apoptotic signaling pathway GO:2001233 197 0.055
cdc42 protein signal transduction GO:0032488 0 0.055
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.055
neutrophil migration GO:1990266 37 0.054
negative regulation of macrophage apoptotic process GO:2000110 3 0.054
eosinophil activation GO:0043307 1 0.054
regulation of eosinophil migration GO:2000416 2 0.054
response to interleukin 18 GO:0070673 4 0.054
Mouse
regulation of alpha beta t cell activation GO:0046634 53 0.054
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.053
reactive nitrogen species metabolic process GO:2001057 0 0.053
homeostasis of number of cells GO:0048872 210 0.053
negative regulation of protein metabolic process GO:0051248 282 0.053
Mouse
positive regulation of dendritic cell chemotaxis GO:2000510 1 0.053
cellular ion homeostasis GO:0006873 165 0.052
thymocyte migration GO:0072679 2 0.052
membrane organization GO:0061024 245 0.052
muscle cell differentiation GO:0042692 261 0.052
blood circulation GO:0008015 195 0.050
interleukin 1 beta production GO:0032611 30 0.050
regulation of proteolysis GO:0030162 164 0.050
regulation of t cell extravasation GO:2000407 3 0.050
regulation of production of molecular mediator of immune response GO:0002700 65 0.050
positive regulation of protein modification process GO:0031401 299 0.050
regulation of body fluid levels GO:0050878 162 0.050
positive regulation of cell migration GO:0030335 109 0.050
positive regulation of mapk cascade GO:0043410 170 0.049
ras protein signal transduction GO:0007265 77 0.049
calcium ion transport GO:0006816 159 0.048
chemotaxis GO:0006935 247 0.048
eosinophil activation involved in immune response GO:0002278 1 0.048
regulation of vesicle mediated transport GO:0060627 139 0.048
positive regulation of t cell differentiation GO:0045582 52 0.047
Mouse
interleukin 1 beta secretion GO:0050702 16 0.047
peptide transport GO:0015833 133 0.047
Mouse
protein catabolic process GO:0030163 221 0.047
negative regulation of protein secretion GO:0050709 20 0.046
activation of immune response GO:0002253 138 0.046
epidermis development GO:0008544 187 0.046
neutrophil mediated cytotoxicity GO:0070942 8 0.046
myeloid cell differentiation GO:0030099 233 0.045
positive regulation of t cell costimulation GO:2000525 2 0.045
striated muscle tissue development GO:0014706 293 0.045
regulation of t helper 2 cell cytokine production GO:2000551 3 0.045
regulation of dendritic cell chemotaxis GO:2000508 1 0.045
nitrogen compound transport GO:0071705 271 0.045
Mouse
cell surface pattern recognition receptor signaling pathway GO:0002752 2 0.045
mucopolysaccharide metabolic process GO:1903510 25 0.045
glycoprotein biosynthetic process GO:0009101 89 0.045
reactive oxygen species biosynthetic process GO:1903409 8 0.045
innate immune response GO:0045087 157 0.044
cytokine production involved in immune response GO:0002367 34 0.044
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.043
regulation of cd8 positive alpha beta t cell extravasation GO:2000449 3 0.043
protein localization to organelle GO:0033365 185 0.043
Mouse
carboxylic acid transport GO:0046942 100 0.043
angiogenesis GO:0001525 201 0.043
germ cell development GO:0007281 185 0.043
positive regulation of cd8 positive alpha beta t cell extravasation GO:2000451 2 0.043
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.043
regulation of membrane potential GO:0042391 192 0.043
cell recognition GO:0008037 83 0.042
single organismal cell cell adhesion GO:0016337 131 0.042
single organism cell adhesion GO:0098602 156 0.042
regulation of cytoplasmic transport GO:1903649 112 0.042
Mouse
positive regulation of immunoglobulin production GO:0002639 28 0.042
neutrophil mediated killing of symbiont cell GO:0070943 8 0.042
alpha beta t cell differentiation GO:0046632 69 0.041
Mouse
t cell activation involved in immune response GO:0002286 43 0.041
Mouse
positive regulation of protein catabolic process GO:0045732 60 0.041
positive regulation of lymphocyte differentiation GO:0045621 61 0.041
Mouse
positive regulation of neutrophil mediated killing of symbiont cell GO:0070961 1 0.041
chemokine metabolic process GO:0050755 10 0.041
Mouse
killing by host of symbiont cells GO:0051873 11 0.040
regulation of interleukin 8 production GO:0032677 3 0.040
engulfment of apoptotic cell GO:0043652 3 0.040
maintenance of location GO:0051235 89 0.040
glycoprotein metabolic process GO:0009100 116 0.040
cell cell recognition GO:0009988 44 0.040
cellular response to lipopolysaccharide GO:0071222 77 0.040
activation of innate immune response GO:0002218 56 0.040
t helper 1 cell differentiation GO:0045063 13 0.040
Mouse
regulation of intracellular protein transport GO:0033157 82 0.039
Mouse
negative regulation of response to cytokine stimulus GO:0060761 9 0.039
Mouse
regulation of cellular component biogenesis GO:0044087 181 0.039
regulation of protein catabolic process GO:0042176 108 0.039
positive regulation of thymocyte migration GO:2000412 2 0.039
protein import GO:0017038 101 0.039
Mouse
regulation of peptide transport GO:0090087 91 0.039
Mouse
regulation of leukocyte mediated cytotoxicity GO:0001910 38 0.039
positive regulation of t cell proliferation GO:0042102 52 0.039
macrophage chemotaxis GO:0048246 14 0.039
cd8 positive alpha beta t cell extravasation GO:0035697 3 0.039
cellular divalent inorganic cation homeostasis GO:0072503 127 0.038
positive regulation of acute inflammatory response GO:0002675 16 0.038
regulation of kinase activity GO:0043549 249 0.038
protein localization to nucleus GO:0034504 121 0.038
Mouse
positive regulation of cellular catabolic process GO:0031331 148 0.038
purine ribonucleotide catabolic process GO:0009154 208 0.038
cd4 positive alpha beta t cell activation GO:0035710 45 0.037
Mouse
amide transport GO:0042886 138 0.037
Mouse
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.037
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.037
endomembrane system organization GO:0010256 147 0.037
regulation of protein import into nucleus GO:0042306 52 0.037
Mouse
neutrophil mediated immunity GO:0002446 19 0.037
organophosphate biosynthetic process GO:0090407 122 0.037
regulation of intracellular transport GO:0032386 159 0.037
Mouse
signal transduction in absence of ligand GO:0038034 55 0.036
positive regulation of cell motility GO:2000147 116 0.036
regulation of organelle organization GO:0033043 289 0.036
positive regulation of t cell extravasation GO:2000409 2 0.036
ribose phosphate metabolic process GO:0019693 291 0.036
regulation of cellular response to stress GO:0080135 159 0.035
t cell differentiation GO:0030217 174 0.035
Mouse
helper t cell chemotaxis GO:0035704 1 0.035
cellular response to acid chemical GO:0071229 68 0.035
purine nucleoside metabolic process GO:0042278 241 0.035
negative regulation of phosphate metabolic process GO:0045936 184 0.035
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.034
myeloid cell apoptotic process GO:0033028 22 0.034
neuron death GO:0070997 154 0.034
regulation of monocyte extravasation GO:2000437 2 0.034
modification dependent protein catabolic process GO:0019941 133 0.034
positive regulation of cell adhesion GO:0045785 80 0.034
small gtpase mediated signal transduction GO:0007264 97 0.033
developmental growth involved in morphogenesis GO:0060560 138 0.033
mapk cascade GO:0000165 281 0.033
regulation of t cell costimulation GO:2000523 2 0.033
ribonucleotide metabolic process GO:0009259 291 0.033
regulation of neutrophil mediated killing of symbiont cell GO:0070949 2 0.033
regulation of interleukin 5 production GO:0032674 10 0.033
t cell differentiation involved in immune response GO:0002292 30 0.033
Mouse
cellular response to lipid GO:0071396 145 0.033
regulation of mapk cascade GO:0043408 248 0.032
transmembrane transport GO:0055085 412 0.032
positive regulation of cytoplasmic transport GO:1903651 40 0.032
Mouse
muscle tissue development GO:0060537 308 0.032
positive regulation of cellular protein catabolic process GO:1903364 34 0.032
purine containing compound metabolic process GO:0072521 311 0.032
response to growth factor GO:0070848 198 0.032
antibacterial peptide biosynthetic process GO:0002780 2 0.032
cellular ketone metabolic process GO:0042180 84 0.031
negative regulation of apoptotic signaling pathway GO:2001234 104 0.031
regulation of angiogenesis GO:0045765 81 0.031
cellular metal ion homeostasis GO:0006875 151 0.031
antibacterial peptide production GO:0002778 2 0.031
leukocyte proliferation GO:0070661 172 0.031
neutrophil mediated killing of bacterium GO:0070944 6 0.031
cell type specific apoptotic process GO:0097285 268 0.031
negative regulation of phosphorus metabolic process GO:0010563 184 0.030
positive regulation of monocyte extravasation GO:2000439 1 0.030
endocrine process GO:0050886 39 0.030
positive regulation of transcription factor import into nucleus GO:0042993 8 0.030
Mouse
compound eye development GO:0048749 1 0.030
positive regulation of interferon gamma production GO:0032729 39 0.030
Mouse
glycosyl compound catabolic process GO:1901658 206 0.030
response to oxidative stress GO:0006979 123 0.029
immune complex clearance GO:0002434 2 0.029
ribonucleoside metabolic process GO:0009119 245 0.029
protein targeting GO:0006605 143 0.029
Mouse
positive regulation of cellular amine metabolic process GO:0033240 5 0.029
regulation of multi organism process GO:0043900 111 0.029
positive regulation of kinase activity GO:0033674 155 0.029
regulation of eosinophil degranulation GO:0043309 1 0.029
inflammatory response to wounding GO:0090594 4 0.029
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.029
positive regulation of cell killing GO:0031343 33 0.029
regulation of ion transport GO:0043269 215 0.029
nucleotide catabolic process GO:0009166 217 0.029
calcium ion transport into cytosol GO:0060402 48 0.029
regulation of lymphocyte differentiation GO:0045619 107 0.029
Mouse
axonogenesis GO:0007409 274 0.028
positive regulation of protein kinase activity GO:0045860 144 0.028
regulation of cell killing GO:0031341 40 0.028
aromatic compound catabolic process GO:0019439 286 0.028
interleukin 1 secretion GO:0050701 16 0.028
cellular macromolecule catabolic process GO:0044265 206 0.028
positive regulation of alpha beta t cell activation GO:0046635 39 0.028
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation GO:2000526 1 0.028
positive regulation of neutrophil mediated cytotoxicity GO:0070960 1 0.028
positive regulation of chemotaxis GO:0050921 38 0.028
regulation of epithelial cell proliferation GO:0050678 141 0.028
regulation of neutrophil mediated killing of gram negative bacterium GO:0070951 1 0.028
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 50 0.028
metal ion homeostasis GO:0055065 189 0.028
endocytosis GO:0006897 168 0.027
glycosyl compound metabolic process GO:1901657 246 0.027
positive regulation of immune complex clearance by monocytes and macrophages GO:0090265 2 0.027
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.027
microglial cell activation involved in immune response GO:0002282 1 0.027
regulation of immune complex clearance by monocytes and macrophages GO:0090264 2 0.027
single organism nuclear import GO:1902593 95 0.027
Mouse
detection of yeast GO:0001879 2 0.027
cellular response to molecule of bacterial origin GO:0071219 83 0.027
monocyte extravasation GO:0035696 2 0.027
regulation of t cell proliferation GO:0042129 92 0.027
leukocyte degranulation GO:0043299 27 0.027
purine nucleoside triphosphate catabolic process GO:0009146 203 0.027
immune complex clearance by monocytes and macrophages GO:0002436 2 0.026
positive regulation of homeostatic process GO:0032846 64 0.026
extracellular structure organization GO:0043062 148 0.026
positive regulation of b cell chemotaxis GO:2000538 2 0.026
b cell mediated immunity GO:0019724 71 0.026
regulation of t cell mediated immunity GO:0002709 34 0.026
negative regulation of cell migration GO:0030336 59 0.026
cellular response to biotic stimulus GO:0071216 92 0.026
purine ribonucleotide metabolic process GO:0009150 290 0.026
interleukin 1 production GO:0032612 31 0.026
muscle contraction GO:0006936 101 0.026
nucleoside metabolic process GO:0009116 246 0.026
response to decreased oxygen levels GO:0036293 59 0.026
tumor necrosis factor production GO:0032640 50 0.026
regulation of interleukin 1 beta production GO:0032651 25 0.025
nucleotide metabolic process GO:0009117 332 0.025
multi multicellular organism process GO:0044706 109 0.025
multicellular organismal homeostasis GO:0048871 164 0.025
negative regulation of chemokine biosynthetic process GO:0045079 2 0.025
Mouse
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.025
interleukin 4 production GO:0032633 24 0.025
skeletal muscle fiber development GO:0048741 58 0.025
immunoglobulin secretion GO:0048305 17 0.025
regulation of alpha beta t cell proliferation GO:0046640 18 0.025
transcription factor import into nucleus GO:0042991 26 0.025
Mouse
disruption of cells of other organism involved in symbiotic interaction GO:0051818 13 0.024
regulation of hormone levels GO:0010817 211 0.024
regulation of response to cytokine stimulus GO:0060759 23 0.024
Mouse
plasma membrane organization GO:0007009 90 0.024
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.024
positive regulation of t helper 2 cell cytokine production GO:2000553 3 0.024
nucleobase containing small molecule metabolic process GO:0055086 352 0.024
antigen receptor mediated signaling pathway GO:0050851 64 0.024
cellular calcium ion homeostasis GO:0006874 119 0.024
regulation of b cell chemotaxis GO:2000537 2 0.024
modification of morphology or physiology of other organism GO:0035821 18 0.024
eosinophil mediated immunity GO:0002447 1 0.024
morphogenesis of a branching epithelium GO:0061138 193 0.024
regulation of protein localization to nucleus GO:1900180 60 0.024
Mouse
purine nucleoside catabolic process GO:0006152 205 0.024
regulation of chemotaxis GO:0050920 53 0.024
interleukin 10 secretion GO:0072608 4 0.024
negative regulation of cell motility GO:2000146 61 0.024
amino acid transport GO:0006865 61 0.024
organonitrogen compound catabolic process GO:1901565 264 0.024
regulation of acute inflammatory response to non antigenic stimulus GO:0002877 2 0.024
positive regulation of intracellular transport GO:0032388 70 0.024
Mouse
establishment of protein localization to organelle GO:0072594 118 0.024
Mouse
regulation of defense response to bacterium GO:1900424 3 0.023
response to organic cyclic compound GO:0014070 198 0.023
regulation of vasculature development GO:1901342 88 0.023
response to oxygen levels GO:0070482 62 0.023
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.023
t cell mediated cytotoxicity GO:0001913 26 0.023
chemokine mediated signaling pathway GO:0070098 17 0.023
striated muscle cell development GO:0055002 125 0.023
positive regulation of ion transport GO:0043270 65 0.023
regulation of immunological synapse formation GO:2000520 2 0.023
gland development GO:0048732 330 0.023
positive regulation of neutrophil chemotaxis GO:0090023 12 0.023
positive regulation of proteolysis GO:0045862 85 0.023
purine nucleoside triphosphate metabolic process GO:0009144 226 0.023
positive regulation of organelle organization GO:0010638 128 0.023
negative regulation of cellular component organization GO:0051129 194 0.023
positive regulation of lymphocyte migration GO:2000403 11 0.023
cellular extravasation GO:0045123 17 0.023
dendritic cell antigen processing and presentation GO:0002468 7 0.022
t helper 17 cell chemotaxis GO:0035705 1 0.022
positive regulation of intracellular protein transport GO:0090316 42 0.022
Mouse
transepithelial chloride transport GO:0030321 4 0.022
carbohydrate derivative catabolic process GO:1901136 231 0.022
anatomical structure homeostasis GO:0060249 145 0.022
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.022
negative regulation of leukocyte mediated immunity GO:0002704 29 0.022
neutrophil mediated killing of gram negative bacterium GO:0070945 4 0.022
regulation of regulated secretory pathway GO:1903305 20 0.022
response to organophosphorus GO:0046683 22 0.022
negative regulation of molecular function GO:0044092 258 0.022
muscle fiber development GO:0048747 76 0.022
hematopoietic stem cell migration GO:0035701 1 0.022
cellular response to molecule of fungal origin GO:0071226 2 0.022
positive regulation of behavior GO:0048520 40 0.022
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.022
regulation of ion homeostasis GO:2000021 64 0.022
regulation of cell adhesion GO:0030155 154 0.022
protein complex localization GO:0031503 19 0.022
Mouse
cellular response to extracellular stimulus GO:0031668 81 0.021
regulation of interleukin 1 beta secretion GO:0050706 15 0.021
skeletal muscle organ development GO:0060538 163 0.021
cellular chemical homeostasis GO:0055082 215 0.021
organelle fission GO:0048285 170 0.021
negative regulation of protein modification process GO:0031400 163 0.021
regulation of cellular response to growth factor stimulus GO:0090287 82 0.021
regulation of fat cell differentiation GO:0045598 81 0.021
membrane invagination GO:0010324 17 0.021
positive regulation of innate immune response GO:0045089 80 0.021
regulation of cellular ketone metabolic process GO:0010565 66 0.021
positive regulation of alpha beta t cell proliferation GO:0046641 12 0.021
rho protein signal transduction GO:0007266 32 0.021
inflammatory response to antigenic stimulus GO:0002437 30 0.021

Il1rl1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.027
disease of cellular proliferation DOID:14566 0 0.027
organ system cancer DOID:0050686 0 0.026