|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.950
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.883
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.873
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.868
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.856
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.853
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.845
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.825
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.823
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.796
|
|
|
|
regulation of interleukin 2 production
|
GO:0032663 |
28 |
0.789
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.757
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.745
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.726
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.703
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.699
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.697
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.688
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.682
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
40 |
0.670
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.669
|
|
|
|
interleukin 2 production
|
GO:0032623 |
33 |
0.655
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.642
|
|
|
|
alpha beta t cell proliferation
|
GO:0046633 |
21 |
0.624
|
|
|
|
t cell selection
|
GO:0045058 |
34 |
0.600
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.590
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.588
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.588
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
61 |
0.575
|
|
|
|
thymic t cell selection
|
GO:0045061 |
22 |
0.569
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.555
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.535
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.528
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.508
|
|
|
|
regulation of alpha beta t cell proliferation
|
GO:0046640 |
18 |
0.504
|
|
|
|
negative thymic t cell selection
|
GO:0045060 |
12 |
0.489
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.486
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.477
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.467
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.465
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.461
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.451
|
Mouse |
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.448
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.446
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.443
|
Mouse |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.442
|
|
|
|
positive t cell selection
|
GO:0043368 |
23 |
0.437
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.435
|
|
|
|
positive regulation of cd8 positive alpha beta t cell extravasation
|
GO:2000451 |
2 |
0.425
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.423
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.423
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.423
|
|
|
|
regulation of inflammatory response to antigenic stimulus
|
GO:0002861 |
21 |
0.421
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.417
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.404
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.403
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.400
|
|
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.398
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.394
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.389
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.378
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.377
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.369
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.367
|
Mouse |
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.363
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.357
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.356
|
Mouse |
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.351
|
Mouse |
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.342
|
|
|
|
inflammatory response to antigenic stimulus
|
GO:0002437 |
30 |
0.334
|
|
|
|
myeloid leukocyte mediated immunity
|
GO:0002444 |
42 |
0.333
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.331
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.329
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.329
|
|
|
|
positive regulation of immunological synapse formation
|
GO:2000522 |
1 |
0.324
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.316
|
|
|
|
positive regulation of t cell receptor signaling pathway
|
GO:0050862 |
4 |
0.313
|
|
|
|
t cell extravasation
|
GO:0072683 |
4 |
0.312
|
|
|
|
dendritic cell differentiation
|
GO:0097028 |
26 |
0.310
|
|
|
|
regulation of dendritic cell chemotaxis
|
GO:2000508 |
1 |
0.308
|
|
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.307
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.302
|
|
|
|
regulation of b cell mediated immunity
|
GO:0002712 |
37 |
0.299
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.297
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.290
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.289
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.288
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.284
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.283
|
|
|
|
regulation of monocyte extravasation
|
GO:2000437 |
2 |
0.283
|
|
|
|
helper t cell chemotaxis
|
GO:0035704 |
1 |
0.282
|
|
|
|
hematopoietic stem cell migration
|
GO:0035701 |
1 |
0.273
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.265
|
|
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
39 |
0.263
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.254
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
50 |
0.248
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
52 |
0.247
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.246
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.243
|
|
|
|
immune complex clearance
|
GO:0002434 |
2 |
0.239
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.235
|
|
|
|
cd4 positive alpha beta t cell lineage commitment
|
GO:0043373 |
6 |
0.233
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.233
|
|
|
|
positive regulation of t cell extravasation
|
GO:2000409 |
2 |
0.230
|
|
|
|
negative t cell selection
|
GO:0043383 |
13 |
0.228
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.228
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.227
|
|
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
42 |
0.226
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.226
|
|
|
|
regulation of t cell extravasation
|
GO:2000407 |
3 |
0.224
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
61 |
0.223
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.222
|
Mouse |
|
|
positive regulation of monocyte extravasation
|
GO:2000439 |
1 |
0.222
|
|
|
|
b cell mediated immunity
|
GO:0019724 |
71 |
0.222
|
|
|
|
antigen processing and presentation
|
GO:0019882 |
47 |
0.221
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.219
|
|
|
|
interleukin 2 biosynthetic process
|
GO:0042094 |
15 |
0.217
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.214
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.212
|
|
|
|
regulation of immune complex clearance by monocytes and macrophages
|
GO:0090264 |
2 |
0.211
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.210
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.210
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.209
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.207
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.205
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.205
|
|
|
|
calcium ion transport into cytosol
|
GO:0060402 |
48 |
0.205
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.203
|
|
|
|
neutrophil migration
|
GO:1990266 |
37 |
0.203
|
Mouse |
|
|
t helper cell differentiation
|
GO:0042093 |
28 |
0.199
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.198
|
|
|
|
t cell differentiation involved in immune response
|
GO:0002292 |
30 |
0.195
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.194
|
|
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
61 |
0.193
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.193
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.192
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.190
|
|
|
|
negative regulation of eosinophil degranulation
|
GO:0043310 |
1 |
0.187
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.186
|
|
|
|
eosinophil degranulation
|
GO:0043308 |
1 |
0.186
|
|
|
|
interleukin 1 production
|
GO:0032612 |
31 |
0.185
|
|
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
41 |
0.184
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.183
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.182
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.181
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.181
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.180
|
|
|
|
interleukin 12 secretion
|
GO:0072610 |
3 |
0.179
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.179
|
|
|
|
interleukin 4 production
|
GO:0032633 |
24 |
0.178
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.174
|
|
|
|
negative regulation of synapse assembly
|
GO:0051964 |
3 |
0.174
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.173
|
|
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.173
|
|
|
|
negative regulation of interleukin 2 production
|
GO:0032703 |
8 |
0.172
|
|
|
|
tolerance induction
|
GO:0002507 |
14 |
0.170
|
|
|
|
positive regulation of chemotaxis
|
GO:0050921 |
38 |
0.169
|
|
|
|
eosinophil activation
|
GO:0043307 |
1 |
0.168
|
|
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.166
|
|
|
|
regulation of eosinophil degranulation
|
GO:0043309 |
1 |
0.165
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.165
|
|
|
|
negative regulation of toll like receptor signaling pathway
|
GO:0034122 |
14 |
0.165
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.164
|
|
|
|
defense response to virus
|
GO:0051607 |
68 |
0.161
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.161
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
55 |
0.160
|
|
|
|
positive regulation of interleukin 2 production
|
GO:0032743 |
19 |
0.160
|
|
|
|
positive regulation of alpha beta t cell activation
|
GO:0046635 |
39 |
0.159
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.156
|
|
|
|
monocyte extravasation
|
GO:0035696 |
2 |
0.155
|
|
|
|
positive regulation of inflammatory response
|
GO:0050729 |
47 |
0.155
|
|
|
|
positive regulation of monocyte chemotaxis
|
GO:0090026 |
2 |
0.154
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.154
|
|
|
|
negative regulation of lymphocyte proliferation
|
GO:0050672 |
45 |
0.153
|
|
|
|
myd88 independent toll like receptor signaling pathway
|
GO:0002756 |
3 |
0.152
|
|
|
|
positive regulation of interleukin 12 production
|
GO:0032735 |
21 |
0.151
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.151
|
|
|
|
interleukin 1 beta secretion
|
GO:0050702 |
16 |
0.150
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.149
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.146
|
|
|
|
positive regulation of dendritic cell chemotaxis
|
GO:2000510 |
1 |
0.145
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.145
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.144
|
Mouse |
|
|
granulocyte chemotaxis
|
GO:0071621 |
39 |
0.143
|
Mouse |
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.142
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.142
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.141
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.140
|
|
|
|
myeloid dendritic cell activation
|
GO:0001773 |
25 |
0.139
|
|
|
|
regulation of b cell proliferation
|
GO:0030888 |
39 |
0.137
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.136
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.136
|
|
|
|
detection of hypoxic conditions in blood by chemoreceptor signaling
|
GO:0002007 |
1 |
0.136
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.135
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.135
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.134
|
|
|
|
regulation of lymphocyte anergy
|
GO:0002911 |
4 |
0.133
|
|
|
|
negative regulation of regulatory t cell differentiation
|
GO:0045590 |
2 |
0.132
|
|
|
|
oligodendrocyte differentiation
|
GO:0048709 |
53 |
0.131
|
|
|
|
somatic diversification of immunoglobulins involved in immune response
|
GO:0002208 |
36 |
0.131
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.131
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.130
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.128
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.127
|
|
|
|
regulation of alpha beta t cell differentiation
|
GO:0046637 |
35 |
0.125
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.125
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.124
|
|
|
|
humoral immune response
|
GO:0006959 |
57 |
0.123
|
|
|
|
cd4 positive alpha beta t cell differentiation involved in immune response
|
GO:0002294 |
28 |
0.123
|
|
|
|
negative regulation of macrophage apoptotic process
|
GO:2000110 |
3 |
0.122
|
|
|
|
acute inflammatory response
|
GO:0002526 |
41 |
0.121
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.121
|
|
|
|
positive regulation of t cell costimulation
|
GO:2000525 |
2 |
0.120
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.120
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.119
|
Mouse |
|
|
b cell proliferation
|
GO:0042100 |
53 |
0.119
|
|
|
|
forebrain cell migration
|
GO:0021885 |
58 |
0.118
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.118
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.117
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.116
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.115
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.115
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.115
|
|
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
41 |
0.115
|
|
|
|
interleukin 12 production
|
GO:0032615 |
32 |
0.115
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.115
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.114
|
|
|
|
regulation of cd8 positive alpha beta t cell extravasation
|
GO:2000449 |
3 |
0.114
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
51 |
0.114
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.113
|
Mouse |
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.112
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.112
|
|
|
|
t cell activation involved in immune response
|
GO:0002286 |
43 |
0.112
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.108
|
|
|
|
t cell mediated immunity
|
GO:0002456 |
50 |
0.108
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.107
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.106
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.105
|
|
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.104
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.104
|
|
|
|
regulation of hypersensitivity
|
GO:0002883 |
10 |
0.104
|
|
|
|
regulation of t cell anergy
|
GO:0002667 |
4 |
0.104
|
|
|
|
chemokine mediated signaling pathway
|
GO:0070098 |
17 |
0.103
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
64 |
0.103
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
51 |
0.102
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.102
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.101
|
|
|
|
negative regulation of b cell activation
|
GO:0050869 |
27 |
0.101
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.100
|
|
|
|
acute inflammatory response to antigenic stimulus
|
GO:0002438 |
12 |
0.099
|
|
|
|
immune complex clearance by monocytes and macrophages
|
GO:0002436 |
2 |
0.099
|
|
|
|
negative regulation of inflammatory response
|
GO:0050728 |
61 |
0.099
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.099
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.098
|
|
|
|
lymphocyte migration
|
GO:0072676 |
26 |
0.098
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.097
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.097
|
|
|
|
regulation of t helper 1 type immune response
|
GO:0002825 |
17 |
0.097
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.096
|
|
|
|
regulation of interleukin 1 production
|
GO:0032652 |
26 |
0.096
|
|
|
|
cd8 positive alpha beta t cell extravasation
|
GO:0035697 |
3 |
0.095
|
|
|
|
memory
|
GO:0007613 |
58 |
0.095
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.093
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.092
|
|
|
|
hypersensitivity
|
GO:0002524 |
10 |
0.092
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.091
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.090
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.090
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.090
|
|
|
|
negative regulation of t cell proliferation
|
GO:0042130 |
38 |
0.090
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.089
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.089
|
|
|
|
regulation of interleukin 1 secretion
|
GO:0050704 |
15 |
0.088
|
|
|
|
positive regulation of exocytosis
|
GO:0045921 |
20 |
0.088
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.088
|
|
|
|
interleukin 1 beta production
|
GO:0032611 |
30 |
0.088
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.088
|
|
|
|
positive regulation of hematopoietic stem cell migration
|
GO:2000473 |
1 |
0.087
|
|
|
|
regulation of leukocyte degranulation
|
GO:0043300 |
20 |
0.087
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.087
|
|
|
|
regulation of t cell mediated immunity
|
GO:0002709 |
34 |
0.087
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.087
|
|
|
|
regulation of interleukin 1 beta secretion
|
GO:0050706 |
15 |
0.087
|
|
|
|
regulation of monocyte chemotaxis
|
GO:0090025 |
3 |
0.087
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.086
|
|
|
|
regulation of interleukin 12 production
|
GO:0032655 |
30 |
0.086
|
|
|
|
eosinophil mediated immunity
|
GO:0002447 |
1 |
0.086
|
|
|
|
cellular extravasation
|
GO:0045123 |
17 |
0.085
|
|
|
|
t helper 1 type immune response
|
GO:0042088 |
25 |
0.085
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.085
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.084
|
|
|
|
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation
|
GO:2000526 |
1 |
0.084
|
|
|
|
negative regulation of inflammatory response to antigenic stimulus
|
GO:0002862 |
10 |
0.084
|
|
|
|
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002823 |
23 |
0.084
|
|
|
|
positive regulation of acute inflammatory response to antigenic stimulus
|
GO:0002866 |
7 |
0.083
|
|
|
|
leukocyte cell cell adhesion
|
GO:0007159 |
14 |
0.083
|
|
|
|
response to interferon gamma
|
GO:0034341 |
34 |
0.083
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.083
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.083
|
|
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
81 |
0.082
|
|
|
|
positive regulation of activation of membrane attack complex
|
GO:0001970 |
2 |
0.082
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.081
|
|
|
|
positive regulation of inflammatory response to antigenic stimulus
|
GO:0002863 |
11 |
0.081
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.080
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.079
|
Mouse |
|
|
alpha beta t cell activation involved in immune response
|
GO:0002287 |
31 |
0.078
|
|
|
|
isotype switching to igg isotypes
|
GO:0048291 |
10 |
0.078
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.078
|
|
|
|
regulation of interleukin 1 beta production
|
GO:0032651 |
25 |
0.077
|
|
|
|
positive regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903557 |
31 |
0.077
|
|
|
|
t cell costimulation
|
GO:0031295 |
14 |
0.077
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.077
|
|
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.077
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.076
|
|
|
|
positive regulation of gliogenesis
|
GO:0014015 |
27 |
0.076
|
Mouse |
|
|
negative regulation of leukocyte proliferation
|
GO:0070664 |
46 |
0.076
|
|
|
|
lymphocyte anergy
|
GO:0002249 |
4 |
0.075
|
|
|
|
regulation of acute inflammatory response
|
GO:0002673 |
27 |
0.075
|
|
|
|
t helper 17 cell chemotaxis
|
GO:0035705 |
1 |
0.075
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.075
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.074
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.074
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.073
|
|
|
|
eosinophil activation involved in immune response
|
GO:0002278 |
1 |
0.071
|
|
|
|
mature dendritic cell differentiation
|
GO:0097029 |
3 |
0.071
|
|
|
|
negative regulation of type 2 immune response
|
GO:0002829 |
8 |
0.071
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.070
|
Mouse |
|
|
positive regulation of response to wounding
|
GO:1903036 |
66 |
0.070
|
|
|
|
cytokine production involved in immune response
|
GO:0002367 |
34 |
0.069
|
|
|
|
positive regulation of lymphocyte anergy
|
GO:0002913 |
4 |
0.069
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.069
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.068
|
|
|
|
negative regulation of b cell proliferation
|
GO:0030889 |
13 |
0.067
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.067
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.066
|
|
|
|
lymph node development
|
GO:0048535 |
18 |
0.066
|
|
|
|
positive regulation of behavior
|
GO:0048520 |
40 |
0.066
|
|
|
|
myeloid cell activation involved in immune response
|
GO:0002275 |
34 |
0.066
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.066
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.066
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
71 |
0.065
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.065
|
Mouse |
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.065
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.065
|
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.065
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.065
|
|
|
|
inflammatory cell apoptotic process
|
GO:0006925 |
11 |
0.064
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.064
|
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
77 |
0.064
|
|
|
|
phospholipid transfer to membrane
|
GO:0006649 |
2 |
0.064
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.064
|
|
|
|
interleukin 10 secretion
|
GO:0072608 |
4 |
0.063
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.062
|
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.062
|
|
|
|
regulation of interleukin 2 biosynthetic process
|
GO:0045076 |
13 |
0.062
|
|
|
|
positive regulation of acute inflammatory response
|
GO:0002675 |
16 |
0.062
|
|
|
|
alpha beta t cell lineage commitment
|
GO:0002363 |
7 |
0.062
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.062
|
|
|
|
regulation of mesenchymal cell proliferation involved in ureter development
|
GO:0072199 |
3 |
0.062
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.061
|
|
|
|
granulocyte activation
|
GO:0036230 |
10 |
0.061
|
|
|
|
telencephalon cell migration
|
GO:0022029 |
55 |
0.061
|
|
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.061
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.061
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.061
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.060
|
|
|
|
regulation of isotype switching to igg isotypes
|
GO:0048302 |
10 |
0.060
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.060
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.059
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.058
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
29 |
0.058
|
|
|
|
regulation of calcium mediated signaling
|
GO:0050848 |
19 |
0.058
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.058
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.058
|
|
|
|
regulation of t cell costimulation
|
GO:2000523 |
2 |
0.057
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.057
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.057
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.057
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.056
|
|
|
|
negative regulation of adaptive immune response
|
GO:0002820 |
25 |
0.056
|
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.056
|
|
|
|
positive regulation of alpha beta t cell proliferation
|
GO:0046641 |
12 |
0.056
|
|
|
|
regulation of immunological synapse formation
|
GO:2000520 |
2 |
0.056
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
56 |
0.056
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
88 |
0.056
|
|
|
|
positive regulation of interferon alpha production
|
GO:0032727 |
4 |
0.056
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.056
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.055
|
|
|
|
regulation of myd88 independent toll like receptor signaling pathway
|
GO:0034127 |
1 |
0.055
|
|
|
|
plasma membrane organization
|
GO:0007009 |
90 |
0.055
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.055
|
|
|
|
regulation of toll like receptor 2 signaling pathway
|
GO:0034135 |
3 |
0.055
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.055
|
|
|
|
alpha beta t cell differentiation involved in immune response
|
GO:0002293 |
30 |
0.054
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.054
|
|
|
|
regulation of immunoglobulin mediated immune response
|
GO:0002889 |
37 |
0.053
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.053
|
|
|
|
interleukin 1 secretion
|
GO:0050701 |
16 |
0.053
|
|
|
|
regulation of gliogenesis
|
GO:0014013 |
50 |
0.052
|
Mouse |
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.052
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.052
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
49 |
0.052
|
|
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.052
|
|
|
|
developmental cell growth
|
GO:0048588 |
84 |
0.051
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.051
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.051
|
|
|
|
regulation of neutrophil chemotaxis
|
GO:0090022 |
14 |
0.051
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.050
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.050
|
|
|
|
olfactory learning
|
GO:0008355 |
2 |
0.050
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.050
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.050
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.050
|
|
|
|
regulation of regulated secretory pathway
|
GO:1903305 |
20 |
0.049
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.049
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.049
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.049
|
|
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
70 |
0.049
|
|
|
|
purinergic nucleotide receptor signaling pathway
|
GO:0035590 |
3 |
0.049
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.049
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.048
|
|
|
|
positive regulation of alpha beta t cell differentiation
|
GO:0046638 |
28 |
0.048
|
|
|
|
positive regulation of immune complex clearance by monocytes and macrophages
|
GO:0090265 |
2 |
0.048
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.048
|
|
|
|
t cell migration
|
GO:0072678 |
19 |
0.048
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
53 |
0.048
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.047
|
|
|
|
somatic recombination of immunoglobulin genes involved in immune response
|
GO:0002204 |
36 |
0.047
|
|
|
|
negative regulation of interleukin 5 production
|
GO:0032714 |
4 |
0.047
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.047
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.046
|
|
|
|
dna recombination
|
GO:0006310 |
92 |
0.046
|
|
|
|
somatic diversification of immune receptors
|
GO:0002200 |
53 |
0.046
|
|
|
|
interferon beta biosynthetic process
|
GO:0045350 |
4 |
0.046
|
|
|
|
positive regulation of jak stat cascade
|
GO:0046427 |
22 |
0.046
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.046
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.045
|
Mouse |
|
|
regulation of systemic arterial blood pressure by chemoreceptor signaling
|
GO:0001979 |
1 |
0.045
|
|
|
|
myeloid dendritic cell differentiation
|
GO:0043011 |
16 |
0.045
|
|
|
|
immunoglobulin production
|
GO:0002377 |
73 |
0.045
|
|
|
|
leukocyte homeostasis
|
GO:0001776 |
79 |
0.045
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.045
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.044
|
|
|
|
dendritic spine maintenance
|
GO:0097062 |
4 |
0.044
|
|
|
|
t cell anergy
|
GO:0002870 |
4 |
0.044
|
|
|
|
negative regulation of myeloid dendritic cell activation
|
GO:0030886 |
3 |
0.044
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.044
|
|
|
|
regulation of antigen processing and presentation
|
GO:0002577 |
10 |
0.044
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.044
|
|
|
|
regulation of interleukin 4 production
|
GO:0032673 |
18 |
0.044
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.043
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.043
|
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
52 |
0.043
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.043
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.042
|
|
|
|
regulation of lymphocyte apoptotic process
|
GO:0070228 |
41 |
0.042
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.042
|
|
|
|
negative regulation of lymphocyte differentiation
|
GO:0045620 |
32 |
0.042
|
|
|
|
cardiac muscle tissue growth involved in heart morphogenesis
|
GO:0003245 |
1 |
0.042
|
|
|
|
biomineral tissue development
|
GO:0031214 |
64 |
0.042
|
|
|
|
cofactor transport
|
GO:0051181 |
4 |
0.041
|
|
|
|
neutrophil chemotaxis
|
GO:0030593 |
36 |
0.041
|
Mouse |
|
|
cd4 positive or cd8 positive alpha beta t cell lineage commitment
|
GO:0043369 |
8 |
0.041
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.041
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.041
|
|
|
|
regulation of type 2 immune response
|
GO:0002828 |
18 |
0.041
|
|
|
|
cd8 positive alpha beta t cell activation
|
GO:0036037 |
9 |
0.041
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.040
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.040
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.040
|
|
|
|
regulation of acute inflammatory response to antigenic stimulus
|
GO:0002864 |
10 |
0.040
|
|
|
|
positive regulation of isotype switching to igg isotypes
|
GO:0048304 |
7 |
0.040
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.040
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.039
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.039
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
46 |
0.039
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.039
|
|
|
|
negative regulation of myeloid leukocyte differentiation
|
GO:0002762 |
20 |
0.039
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
93 |
0.039
|
|
|
|
positive regulation of interleukin 1 beta secretion
|
GO:0050718 |
14 |
0.039
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.039
|
|
|
|
learning
|
GO:0007612 |
98 |
0.038
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.038
|
|
|
|
type i interferon signaling pathway
|
GO:0060337 |
10 |
0.038
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.038
|
|
|
|
microglial cell activation
|
GO:0001774 |
3 |
0.038
|
|
|
|
t cell lineage commitment
|
GO:0002360 |
13 |
0.038
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
65 |
0.038
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.038
|
|
