|
|
t cell activation involved in immune response
|
GO:0002286 |
43 |
0.945
|
|
|
|
t helper cell differentiation
|
GO:0042093 |
28 |
0.945
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.935
|
|
|
|
cd4 positive alpha beta t cell differentiation involved in immune response
|
GO:0002294 |
28 |
0.928
|
|
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.912
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.907
|
|
|
|
regulation of antimicrobial humoral response
|
GO:0002759 |
3 |
0.897
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.875
|
|
|
|
alpha beta t cell differentiation involved in immune response
|
GO:0002293 |
30 |
0.870
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.866
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.843
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.821
|
|
|
|
t cell differentiation involved in immune response
|
GO:0002292 |
30 |
0.820
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.811
|
|
|
|
cd4 positive alpha beta t cell lineage commitment
|
GO:0043373 |
6 |
0.810
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.805
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.799
|
|
|
|
positive regulation of inflammatory response
|
GO:0050729 |
47 |
0.787
|
|
|
|
alpha beta t cell activation involved in immune response
|
GO:0002287 |
31 |
0.758
|
|
|
|
progesterone metabolic process
|
GO:0042448 |
4 |
0.741
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.697
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.696
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.693
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
40 |
0.692
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.692
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.689
|
|
|
|
isotype switching to ige isotypes
|
GO:0048289 |
7 |
0.684
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.674
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.658
|
|
|
|
alpha beta t cell lineage commitment
|
GO:0002363 |
7 |
0.654
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.648
|
|
|
|
regulation of type 2 immune response
|
GO:0002828 |
18 |
0.640
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.624
|
|
|
|
b cell mediated immunity
|
GO:0019724 |
71 |
0.623
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.614
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.613
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.608
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.606
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.597
|
|
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
52 |
0.595
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.593
|
|
|
|
response to interleukin 15
|
GO:0070672 |
3 |
0.589
|
|
|
|
regulation of b cell mediated immunity
|
GO:0002712 |
37 |
0.586
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.575
|
|
|
|
immunoglobulin production
|
GO:0002377 |
73 |
0.569
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.564
|
|
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
70 |
0.559
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.559
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.553
|
|
|
|
somatic diversification of immunoglobulins
|
GO:0016445 |
43 |
0.547
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.537
|
|
|
|
t helper cell lineage commitment
|
GO:0002295 |
6 |
0.527
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.525
|
|
|
|
regulation of macrophage activation
|
GO:0043030 |
17 |
0.514
|
|
|
|
defense response to protozoan
|
GO:0042832 |
25 |
0.508
|
|
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
41 |
0.491
|
|
|
|
cd4 positive or cd8 positive alpha beta t cell lineage commitment
|
GO:0043369 |
8 |
0.489
|
|
|
|
t helper 2 cell differentiation
|
GO:0045064 |
12 |
0.479
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.474
|
|
|
|
somatic cell dna recombination
|
GO:0016444 |
51 |
0.471
|
|
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
61 |
0.469
|
|
|
|
type 2 immune response
|
GO:0042092 |
23 |
0.467
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.467
|
|
|
|
t cell selection
|
GO:0045058 |
34 |
0.459
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.455
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.452
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.440
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.429
|
|
|
|
b cell activation involved in immune response
|
GO:0002312 |
50 |
0.422
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.421
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.417
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.417
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.415
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.414
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.412
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.412
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
38 |
0.408
|
|
|
|
positive regulation of lymphocyte mediated immunity
|
GO:0002708 |
62 |
0.405
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.403
|
|
|
|
negative regulation of inflammatory response
|
GO:0050728 |
61 |
0.400
|
|
|
|
regulation of activated t cell proliferation
|
GO:0046006 |
16 |
0.392
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.387
|
|
|
|
natural killer cell proliferation
|
GO:0001787 |
3 |
0.376
|
|
|
|
t helper 1 cell lineage commitment
|
GO:0002296 |
2 |
0.370
|
|
|
|
isotype switching
|
GO:0045190 |
36 |
0.366
|
|
|
|
regulation of immunoglobulin mediated immune response
|
GO:0002889 |
37 |
0.362
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.349
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.345
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.343
|
|
|
|
t helper 1 type immune response
|
GO:0042088 |
25 |
0.342
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.341
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.339
|
|
|
|
positive t cell selection
|
GO:0043368 |
23 |
0.335
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.332
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.330
|
|
|
|
regulation of natural killer cell differentiation
|
GO:0032823 |
11 |
0.329
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.326
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.324
|
|
|
|
steroid metabolic process
|
GO:0008202 |
119 |
0.323
|
|
|
|
natural killer cell activation
|
GO:0030101 |
44 |
0.322
|
|
|
|
somatic diversification of immunoglobulins involved in immune response
|
GO:0002208 |
36 |
0.322
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.316
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.315
|
|
|
|
positive regulation of b cell activation
|
GO:0050871 |
49 |
0.313
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.309
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
89 |
0.309
|
|
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.308
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.305
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.305
|
|
|
|
somatic recombination of immunoglobulin gene segments
|
GO:0016447 |
42 |
0.304
|
|
|
|
somatic recombination of immunoglobulin genes involved in immune response
|
GO:0002204 |
36 |
0.296
|
|
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
45 |
0.296
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.293
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.290
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.279
|
|
|
|
syncytium formation
|
GO:0006949 |
43 |
0.277
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.276
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
121 |
0.274
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
42 |
0.271
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.270
|
|
|
|
antimicrobial peptide biosynthetic process
|
GO:0002777 |
2 |
0.270
|
|
|
|
somatic diversification of immune receptors via germline recombination within a single locus
|
GO:0002562 |
51 |
0.269
|
|
|
|
antibacterial peptide biosynthetic process
|
GO:0002780 |
2 |
0.268
|
|
|
|
positive regulation of macrophage activation
|
GO:0043032 |
10 |
0.265
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.264
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.264
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.261
|
|
|
|
regulation of isotype switching to ige isotypes
|
GO:0048293 |
7 |
0.253
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.247
|
|
|
|
positive regulation of isotype switching to ige isotypes
|
GO:0048295 |
4 |
0.243
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
52 |
0.241
|
|
|
|
lipid storage
|
GO:0019915 |
36 |
0.236
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.235
|
|
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.235
|
|
|
|
cellular amide metabolic process
|
GO:0043603 |
58 |
0.226
|
|
|
|
type i interferon signaling pathway
|
GO:0060337 |
10 |
0.224
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.223
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.223
|
|
|
|
positive regulation of activated t cell proliferation
|
GO:0042104 |
8 |
0.223
|
|
|
|
regulation of mast cell differentiation
|
GO:0060375 |
3 |
0.223
|
|
|
|
humoral immune response
|
GO:0006959 |
57 |
0.219
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.212
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.212
|
|
|
|
negative regulation of cellular carbohydrate metabolic process
|
GO:0010677 |
19 |
0.211
|
|
|
|
positive regulation of b cell mediated immunity
|
GO:0002714 |
26 |
0.208
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.208
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.208
|
|
|
|
regulation of myeloid leukocyte mediated immunity
|
GO:0002886 |
25 |
0.205
|
|
|
|
sulfur compound metabolic process
|
GO:0006790 |
100 |
0.204
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
119 |
0.203
|
|
|
|
carbohydrate homeostasis
|
GO:0033500 |
128 |
0.202
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.202
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.202
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.200
|
|
|
|
positive regulation of interleukin 2 production
|
GO:0032743 |
19 |
0.198
|
|
|
|
myeloid leukocyte mediated immunity
|
GO:0002444 |
42 |
0.197
|
|
|
|
response to interleukin 4
|
GO:0070670 |
23 |
0.195
|
|
|
|
somatic stem cell maintenance
|
GO:0035019 |
47 |
0.193
|
|
|
|
somatic diversification of immune receptors
|
GO:0002200 |
53 |
0.193
|
|
|
|
negative regulation of syncytium formation by plasma membrane fusion
|
GO:0034242 |
5 |
0.193
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.192
|
|
|
|
mast cell proliferation
|
GO:0070662 |
4 |
0.191
|
|
|
|
positive regulation of isotype switching
|
GO:0045830 |
15 |
0.189
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
42 |
0.188
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.187
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.184
|
|
|
|
defense response to virus
|
GO:0051607 |
68 |
0.183
|
|
|
|
regulation of dna recombination
|
GO:0000018 |
34 |
0.183
|
|
|
|
negative regulation of t cell differentiation
|
GO:0045581 |
23 |
0.181
|
|
|
|
regulation of cd4 positive alpha beta t cell activation
|
GO:2000514 |
24 |
0.180
|
|
|
|
t cell lineage commitment
|
GO:0002360 |
13 |
0.175
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.175
|
|
|
|
cellular response to interleukin 4
|
GO:0071353 |
21 |
0.174
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.172
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.172
|
|
|
|
negative regulation of type 2 immune response
|
GO:0002829 |
8 |
0.171
|
|
|
|
negative regulation of interleukin 10 secretion
|
GO:2001180 |
2 |
0.167
|
|
|
|
dna recombination
|
GO:0006310 |
92 |
0.165
|
|
|
|
myeloid dendritic cell activation
|
GO:0001773 |
25 |
0.165
|
|
|
|
cellular response to x ray
|
GO:0071481 |
2 |
0.163
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.162
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.161
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
61 |
0.160
|
|
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.160
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.160
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.158
|
|
|
|
citrate metabolic process
|
GO:0006101 |
3 |
0.158
|
|
|
|
myeloid dendritic cell differentiation
|
GO:0043011 |
16 |
0.156
|
|
|
|
macrophage fusion
|
GO:0034238 |
3 |
0.156
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.155
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.155
|
|
|
|
cellular response to interferon gamma
|
GO:0071346 |
25 |
0.154
|
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
77 |
0.149
|
|
|
|
jak stat cascade involved in growth hormone signaling pathway
|
GO:0060397 |
4 |
0.148
|
|
|
|
regulation of chemokine secretion
|
GO:0090196 |
4 |
0.146
|
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.143
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.142
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.141
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.138
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.138
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.138
|
|
|
|
positive regulation of leukocyte mediated cytotoxicity
|
GO:0001912 |
31 |
0.137
|
|
|
|
lipopolysaccharide mediated signaling pathway
|
GO:0031663 |
25 |
0.137
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.137
|
|
|
|
regulation of syncytium formation by plasma membrane fusion
|
GO:0060142 |
23 |
0.137
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.136
|
|
|
|
positive regulation of gamma delta t cell differentiation
|
GO:0045588 |
6 |
0.136
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.134
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.133
|
|
|
|
interferon gamma mediated signaling pathway
|
GO:0060333 |
5 |
0.132
|
|
|
|
response to dsrna
|
GO:0043331 |
30 |
0.131
|
|
|
|
negative regulation of b cell activation
|
GO:0050869 |
27 |
0.130
|
|
|
|
regulation of mast cell proliferation
|
GO:0070666 |
4 |
0.128
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.128
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.128
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.128
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.126
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.126
|
|
|
|
cellular modified amino acid metabolic process
|
GO:0006575 |
63 |
0.125
|
|
|
|
female gamete generation
|
GO:0007292 |
74 |
0.125
|
Rat |
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.125
|
|
|
|
interleukin 2 biosynthetic process
|
GO:0042094 |
15 |
0.123
|
|
|
|
immunoglobulin production involved in immunoglobulin mediated immune response
|
GO:0002381 |
43 |
0.123
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.123
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.119
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.119
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.117
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.116
|
|
|
|
positive regulation of immunoglobulin mediated immune response
|
GO:0002891 |
26 |
0.115
|
|
|
|
response to granulocyte macrophage colony stimulating factor
|
GO:0097012 |
3 |
0.115
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.115
|
|
|
|
negative regulation of humoral immune response
|
GO:0002921 |
6 |
0.113
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.113
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.113
|
|
|
|
jak stat cascade
|
GO:0007259 |
42 |
0.112
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.111
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.111
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.110
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.110
|
Rat |
|
|
negative regulation of interleukin 5 production
|
GO:0032714 |
4 |
0.110
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.109
|
|
|
|
acute inflammatory response
|
GO:0002526 |
41 |
0.107
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.107
|
|
|
|
negative regulation of erythrocyte differentiation
|
GO:0045647 |
5 |
0.107
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.106
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.105
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.104
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.104
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.104
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.103
|
|
|
|
regulation of interleukin 2 biosynthetic process
|
GO:0045076 |
13 |
0.103
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.102
|
|
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
75 |
0.102
|
|
|
|
regulation of mast cell activation involved in immune response
|
GO:0033006 |
17 |
0.102
|
|
|
|
interleukin 12 production
|
GO:0032615 |
32 |
0.102
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.101
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.100
|
|
|
|
pyruvate metabolic process
|
GO:0006090 |
28 |
0.100
|
|
|
|
regulation of b cell differentiation
|
GO:0045577 |
23 |
0.099
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.098
|
|
|
|
interleukin 2 production
|
GO:0032623 |
33 |
0.097
|
|
|
|
regulation of natural killer cell activation
|
GO:0032814 |
22 |
0.097
|
|
|
|
memory
|
GO:0007613 |
58 |
0.097
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.097
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.096
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.096
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.096
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.095
|
|
|
|
positive regulation of antimicrobial peptide production
|
GO:0002225 |
1 |
0.095
|
|
|
|
regulation of interleukin 6 production
|
GO:0032675 |
55 |
0.094
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.093
|
|
|
|
regulation of isotype switching
|
GO:0045191 |
22 |
0.093
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.093
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.093
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.092
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.092
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
49 |
0.091
|
|
|
|
segmentation
|
GO:0035282 |
93 |
0.091
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.091
|
|
|
|
alpha amino acid metabolic process
|
GO:1901605 |
59 |
0.090
|
|
|
|
regulation of interleukin 2 production
|
GO:0032663 |
28 |
0.089
|
|
|
|
natural killer cell differentiation
|
GO:0001779 |
21 |
0.088
|
|
|
|
antibacterial peptide production
|
GO:0002778 |
2 |
0.088
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.088
|
|
|
|
regulation of leukocyte mediated cytotoxicity
|
GO:0001910 |
38 |
0.088
|
|
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
39 |
0.087
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.087
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.087
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.087
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.086
|
|
|
|
regulation of natural killer cell proliferation
|
GO:0032817 |
2 |
0.086
|
|
|
|
glucose homeostasis
|
GO:0042593 |
128 |
0.086
|
|
|
|
leukocyte homeostasis
|
GO:0001776 |
79 |
0.086
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.085
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.085
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.085
|
|
|
|
lactation
|
GO:0007595 |
25 |
0.084
|
|
|
|
female gonad development
|
GO:0008585 |
71 |
0.084
|
|
|
|
regulation of immunoglobulin production
|
GO:0002637 |
42 |
0.084
|
|
|
|
phospholipid homeostasis
|
GO:0055091 |
6 |
0.083
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.083
|
|
|
|
development of primary female sexual characteristics
|
GO:0046545 |
73 |
0.083
|
|
|
|
mast cell homeostasis
|
GO:0033023 |
5 |
0.083
|
|
|
|
glial cell apoptotic process
|
GO:0034349 |
3 |
0.082
|
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.082
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.081
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.081
|
|
|
|
mast cell apoptotic process
|
GO:0033024 |
5 |
0.081
|
|
|
|
macromolecule glycosylation
|
GO:0043413 |
55 |
0.081
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.080
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.079
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.079
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
59 |
0.079
|
|
|
|
macrophage activation
|
GO:0042116 |
27 |
0.079
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.079
|
|
|
|
development of secondary male sexual characteristics
|
GO:0046544 |
3 |
0.079
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.078
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.078
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.077
|
|
|
|
positive regulation of notch signaling pathway
|
GO:0045747 |
18 |
0.076
|
|
|
|
glycosylation
|
GO:0070085 |
62 |
0.076
|
|
|
|
negative regulation of lymphocyte differentiation
|
GO:0045620 |
32 |
0.074
|
|
|
|
regulation of alpha beta t cell differentiation
|
GO:0046637 |
35 |
0.074
|
|
|
|
regulation of chemokine production
|
GO:0032642 |
30 |
0.074
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.074
|
|
|
|
nucleotide binding oligomerization domain containing signaling pathway
|
GO:0070423 |
6 |
0.073
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.073
|
|
|
|
carbohydrate catabolic process
|
GO:0016052 |
32 |
0.073
|
|
|
|
glycolytic process
|
GO:0006096 |
20 |
0.073
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.073
|
|
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
38 |
0.073
|
|
|
|
interleukin 4 mediated signaling pathway
|
GO:0035771 |
2 |
0.073
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.072
|
|
|
|
mast cell activation
|
GO:0045576 |
27 |
0.072
|
|
|
|
regulation of cell killing
|
GO:0031341 |
40 |
0.071
|
|
|
|
segment specification
|
GO:0007379 |
15 |
0.071
|
|
|
|
regulation of jak stat cascade
|
GO:0046425 |
34 |
0.071
|
|
|
|
response to alcohol
|
GO:0097305 |
48 |
0.071
|
|
|
|
regulation of cellular carbohydrate metabolic process
|
GO:0010675 |
75 |
0.071
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.070
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.070
|
|
|
|
protein glycosylation
|
GO:0006486 |
55 |
0.070
|
|
|
|
female sex differentiation
|
GO:0046660 |
84 |
0.069
|
|
|
|
regulation of steroid metabolic process
|
GO:0019218 |
39 |
0.069
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.069
|
|
|
|
response to insulin
|
GO:0032868 |
100 |
0.069
|
|
|
|
mucosal associated lymphoid tissue development
|
GO:0048537 |
12 |
0.069
|
|
|
|
negative regulation of glycolytic process
|
GO:0045820 |
4 |
0.069
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.068
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.068
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.067
|
|
|
|
cellular response to type i interferon
|
GO:0071357 |
10 |
0.067
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.067
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.067
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.066
|
|
|
|
body fluid secretion
|
GO:0007589 |
53 |
0.066
|
|
|
|
temperature homeostasis
|
GO:0001659 |
26 |
0.066
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.066
|
|
|
|
regulation of alpha beta t cell proliferation
|
GO:0046640 |
18 |
0.066
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
92 |
0.065
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.065
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.064
|
|
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.063
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.063
|
|
|
|
positive regulation of interleukin 2 biosynthetic process
|
GO:0045086 |
8 |
0.063
|
|
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
30 |
0.063
|
|
|
|
t helper 1 cell differentiation
|
GO:0045063 |
13 |
0.063
|
|
|
|
regulation of mast cell apoptotic process
|
GO:0033025 |
5 |
0.063
|
|
|
|
positive regulation of dna recombination
|
GO:0045911 |
17 |
0.063
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.063
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.062
|
|
|
|
creatinine metabolic process
|
GO:0046449 |
3 |
0.062
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.062
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.061
|
|
|
|
interleukin 13 secretion
|
GO:0072611 |
2 |
0.061
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.061
|
|
|
|
nuclear import
|
GO:0051170 |
95 |
0.061
|
|
|
|
cellular response to granulocyte macrophage colony stimulating factor stimulus
|
GO:0097011 |
3 |
0.060
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
|
GO:1902042 |
11 |
0.060
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
27 |
0.060
|
|
|
|
muscle cell proliferation
|
GO:0033002 |
52 |
0.059
|
|
|
|
response to x ray
|
GO:0010165 |
11 |
0.059
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.059
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.059
|
|
|
|
response to interferon gamma
|
GO:0034341 |
34 |
0.059
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
91 |
0.059
|
|
|
|
hormone metabolic process
|
GO:0042445 |
86 |
0.059
|
|
|
|
leukocyte mediated cytotoxicity
|
GO:0001909 |
62 |
0.058
|
|
|
|
regulation of cd4 positive alpha beta t cell differentiation
|
GO:0043370 |
21 |
0.058
|
|
|
|
positive regulation of alpha beta t cell activation
|
GO:0046635 |
39 |
0.058
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.058
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.058
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.057
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.057
|
|
|
|
extrinsic apoptotic signaling pathway via death domain receptors
|
GO:0008625 |
34 |
0.057
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.057
|
|
|
|
extracellular structure organization
|
GO:0043062 |
148 |
0.057
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.056
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
49 |
0.056
|
|
|
|
icosanoid metabolic process
|
GO:0006690 |
33 |
0.056
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.056
|
|
|
|
myeloid cell apoptotic process
|
GO:0033028 |
22 |
0.056
|
|
|
|
negative regulation of carbohydrate metabolic process
|
GO:0045912 |
19 |
0.056
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.056
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.056
|
|
|
|
response to type i interferon
|
GO:0034340 |
12 |
0.055
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.055
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
88 |
0.055
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.055
|
|
|
|
alpha beta t cell proliferation
|
GO:0046633 |
21 |
0.054
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.054
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.053
|
|
|
|
notch signaling pathway
|
GO:0007219 |
71 |
0.053
|
|
|
|
gene silencing by mirna
|
GO:0035195 |
10 |
0.053
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.053
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.052
|
|
|
|
sterol metabolic process
|
GO:0016125 |
58 |
0.052
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
65 |
0.051
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.051
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.051
|
|
|
|
regulation of b cell proliferation
|
GO:0030888 |
39 |
0.051
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.051
|
|
|
|
regulation of mast cell degranulation
|
GO:0043304 |
16 |
0.050
|
|
|
|
dicarboxylic acid metabolic process
|
GO:0043648 |
18 |
0.050
|
|
|
|
mast cell degranulation
|
GO:0043303 |
19 |
0.050
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
116 |
0.050
|
|
|
|
positive regulation of cell killing
|
GO:0031343 |
33 |
0.050
|
|
|
|
regulation of macrophage fusion
|
GO:0034239 |
3 |
0.050
|
|
|
|
interleukin 11 mediated signaling pathway
|
GO:0038154 |
2 |
0.049
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.049
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
27 |
0.049
|
|
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.048
|
|
|
|
regulated secretory pathway
|
GO:0045055 |
32 |
0.048
|
|
|
|
regulation of insulin receptor signaling pathway
|
GO:0046626 |
21 |
0.048
|
|
|
|
interleukin 2 mediated signaling pathway
|
GO:0038110 |
2 |
0.048
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.048
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.047
|
|
|
|
positive regulation of natural killer cell mediated immunity
|
GO:0002717 |
16 |
0.047
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.047
|
|
|
|
interleukin 1 mediated signaling pathway
|
GO:0070498 |
4 |
0.047
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.047
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.047
|
|
|
|
interleukin 5 secretion
|
GO:0072603 |
2 |
0.047
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.046
|
|
|
|
positive regulation of alpha beta t cell differentiation
|
GO:0046638 |
28 |
0.046
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
57 |
0.046
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.046
|
|
|
|
negative regulation of cd4 positive alpha beta t cell activation
|
GO:2000515 |
10 |
0.045
|
|
|
|
negative regulation of t helper 2 cell differentiation
|
GO:0045629 |
4 |
0.045
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.045
|
|
|
|
cellular response to interleukin 18
|
GO:0071351 |
3 |
0.045
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.044
|
|
|
|
cell killing
|
GO:0001906 |
67 |
0.044
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.044
|
|
|
|
positive regulation of immunoglobulin production
|
GO:0002639 |
28 |
0.044
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.044
|
|
|
|
regulation of natural killer cell mediated cytotoxicity
|
GO:0042269 |
19 |
0.044
|
|
|
|
response to muramyl dipeptide
|
GO:0032495 |
9 |
0.044
|
|
|
|
defense response to gram negative bacterium
|
GO:0050829 |
28 |
0.044
|
|
|
|
negative regulation of cytokine biosynthetic process
|
GO:0042036 |
13 |
0.043
|
|
|
|
response to amino acid
|
GO:0043200 |
37 |
0.043
|
|
|
|
positive regulation of mast cell degranulation
|
GO:0043306 |
10 |
0.043
|
|
|
|
positive regulation of gamma delta t cell activation
|
GO:0046645 |
6 |
0.043
|
|
|
|
transition metal ion transport
|
GO:0000041 |
38 |
0.043
|
|
|
|
spleen development
|
GO:0048536 |
39 |
0.043
|
|
|
|
response to interleukin 2
|
GO:0070669 |
2 |
0.043
|
|
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
86 |
0.043
|
|
|
|
t cell homeostasis
|
GO:0043029 |
35 |
0.042
|
|
|
|
natural killer cell mediated cytotoxicity
|
GO:0042267 |
29 |
0.042
|
|
|
|
mammary gland morphogenesis
|
GO:0060443 |
54 |
0.042
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.042
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.042
|
|
|
|
necrotic cell death
|
GO:0070265 |
30 |
0.042
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.042
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.042
|
|
|
|
response to hypoxia
|
GO:0001666 |
58 |
0.041
|
|
|
|
t helper 17 type immune response
|
GO:0072538 |
9 |
0.041
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.041
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.041
|
|
|
|
regulation of interleukin 5 secretion
|
GO:2000662 |
2 |
0.041
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.040
|
|
|
|
negative regulation of secretion by cell
|
GO:1903531 |
54 |
0.040
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.040
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
68 |
0.040
|
|
|
|
regulation of defense response to virus by host
|
GO:0050691 |
8 |
0.040
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.039
|
|
|
|
regulation of isotype switching to igg isotypes
|
GO:0048302 |
10 |
0.039
|
|
|
|
negative regulation of macrophage fusion
|
GO:0034240 |
1 |
0.039
|
|
|
|
isoleucine metabolic process
|
GO:0006549 |
4 |
0.039
|
|
|
|
positive regulation of natural killer cell activation
|
GO:0032816 |
15 |
0.039
|
|
|
|
positive regulation of antibacterial peptide biosynthetic process
|
GO:0006963 |
1 |
0.038
|
|
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.038
|
|
|
|
ovulation cycle
|
GO:0042698 |
59 |
0.038
|
|
|
|
regulation of regulated secretory pathway
|
GO:1903305 |
20 |
0.038
|
|
