|
|
interleukin 18 mediated signaling pathway
|
GO:0035655 |
2 |
0.999
|
|
|
|
cellular response to interleukin 18
|
GO:0071351 |
3 |
0.997
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.996
|
Human |
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.979
|
|
|
|
interleukin 5 secretion
|
GO:0072603 |
2 |
0.975
|
|
|
|
response to interleukin 1
|
GO:0070555 |
11 |
0.973
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.971
|
Human |
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.966
|
Human |
|
|
antibacterial peptide secretion
|
GO:0002779 |
1 |
0.964
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.963
|
Human |
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.961
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.955
|
|
|
|
positive regulation of b cell mediated immunity
|
GO:0002714 |
26 |
0.945
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.942
|
|
|
|
somatic diversification of immune receptors via germline recombination within a single locus
|
GO:0002562 |
51 |
0.942
|
|
|
|
negative regulation of reactive oxygen species biosynthetic process
|
GO:1903427 |
0 |
0.938
|
|
|
|
negative regulation of inflammatory response to antigenic stimulus
|
GO:0002862 |
10 |
0.931
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.930
|
|
|
|
cell killing
|
GO:0001906 |
67 |
0.928
|
|
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
70 |
0.927
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.920
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.918
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.916
|
|
|
|
antibacterial peptide biosynthetic process
|
GO:0002780 |
2 |
0.913
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.910
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.906
|
|
|
|
somatic diversification of immune receptors
|
GO:0002200 |
53 |
0.897
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.891
|
|
|
|
antibacterial peptide production
|
GO:0002778 |
2 |
0.883
|
|
|
|
regulation of immunoglobulin production
|
GO:0002637 |
42 |
0.882
|
Human |
|
|
somatic diversification of immunoglobulins involved in immune response
|
GO:0002208 |
36 |
0.875
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.873
|
|
|
|
tyrosine phosphorylation of stat1 protein
|
GO:0042508 |
3 |
0.867
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.864
|
|
|
|
t cell differentiation involved in immune response
|
GO:0002292 |
30 |
0.863
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.858
|
|
|
|
fever generation
|
GO:0001660 |
7 |
0.857
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.855
|
|
|
|
inflammatory response to wounding
|
GO:0090594 |
4 |
0.855
|
|
|
|
positive regulation of t helper 1 cell differentiation
|
GO:0045627 |
4 |
0.845
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.844
|
|
|
|
neutrophil mediated killing of gram negative bacterium
|
GO:0070945 |
4 |
0.843
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.836
|
Human |
|
|
innate immune response
|
GO:0045087 |
157 |
0.833
|
|
|
|
lipopolysaccharide mediated signaling pathway
|
GO:0031663 |
25 |
0.830
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.824
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.824
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.809
|
|
|
|
regulation of b cell mediated immunity
|
GO:0002712 |
37 |
0.789
|
|
|
|
immunoglobulin production involved in immunoglobulin mediated immune response
|
GO:0002381 |
43 |
0.778
|
|
|
|
defense response to gram positive bacterium
|
GO:0050830 |
50 |
0.768
|
Human |
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
11 |
0.767
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.765
|
|
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
61 |
0.758
|
|
|
|
b cell mediated immunity
|
GO:0019724 |
71 |
0.758
|
|
|
|
regulation of dna recombination
|
GO:0000018 |
34 |
0.754
|
|
|
|
positive regulation of inflammatory response
|
GO:0050729 |
47 |
0.750
|
Human |
|
|
regulation of neutrophil mediated killing of gram negative bacterium
|
GO:0070951 |
1 |
0.747
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.741
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.741
|
|
|
|
cellular response to amino acid stimulus
|
GO:0071230 |
29 |
0.739
|
|
|
|
somatic recombination of immunoglobulin gene segments
|
GO:0016447 |
42 |
0.735
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.735
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.731
|
|
|
|
natural killer cell activation
|
GO:0030101 |
44 |
0.728
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.725
|
Human |
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.724
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.724
|
Human |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.719
|
|
|
|
negative regulation of chemokine biosynthetic process
|
GO:0045079 |
2 |
0.717
|
|
|
|
defense response to gram negative bacterium
|
GO:0050829 |
28 |
0.709
|
Human |
|
|
inflammatory response
|
GO:0006954 |
244 |
0.701
|
Human |
|
|
cellular response to interferon gamma
|
GO:0071346 |
25 |
0.684
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.683
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.683
|
Human |
|
|
positive regulation of isotype switching to igg isotypes
|
GO:0048304 |
7 |
0.682
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.679
|
|
|
|
regulation of chemokine biosynthetic process
|
GO:0045073 |
8 |
0.677
|
|
|
|
response to interferon gamma
|
GO:0034341 |
34 |
0.677
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.675
|
Human |
|
|
cd4 positive alpha beta t cell cytokine production
|
GO:0035743 |
4 |
0.666
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.666
|
|
|
|
regulation of chemokine production
|
GO:0032642 |
30 |
0.666
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.662
|
Human |
|
|
regulation of chronic inflammatory response to antigenic stimulus
|
GO:0002874 |
3 |
0.655
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.649
|
|
|
|
positive regulation of leukocyte mediated cytotoxicity
|
GO:0001912 |
31 |
0.641
|
|
|
|
somatic recombination of immunoglobulin genes involved in immune response
|
GO:0002204 |
36 |
0.634
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
57 |
0.633
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.620
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.615
|
|
|
|
positive regulation of immunoglobulin mediated immune response
|
GO:0002891 |
26 |
0.615
|
|
|
|
regulation of growth of symbiont in host
|
GO:0044126 |
19 |
0.609
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.602
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.601
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.600
|
Human |
|
|
positive regulation of response to wounding
|
GO:1903036 |
66 |
0.600
|
Human |
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.599
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.599
|
Human |
|
|
negative regulation of inflammatory response
|
GO:0050728 |
61 |
0.599
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.595
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.592
|
|
|
|
organ or tissue specific immune response
|
GO:0002251 |
13 |
0.589
|
Human |
|
|
interleukin 33 mediated signaling pathway
|
GO:0038172 |
1 |
0.589
|
|
|
|
chemokine production
|
GO:0032602 |
34 |
0.587
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.586
|
|
|
|
regulation of chemokine secretion
|
GO:0090196 |
4 |
0.586
|
|
|
|
natural killer cell mediated cytotoxicity
|
GO:0042267 |
29 |
0.583
|
|
|
|
positive regulation of macrophage activation
|
GO:0043032 |
10 |
0.583
|
|
|
|
wound healing involved in inflammatory response
|
GO:0002246 |
4 |
0.575
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
40 |
0.574
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.574
|
Human |
|
|
positive regulation by symbiont of defense related host nitric oxide production
|
GO:0052347 |
1 |
0.572
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.571
|
|
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.571
|
|
|
|
chemokine biosynthetic process
|
GO:0042033 |
8 |
0.567
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.564
|
Human |
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.556
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.548
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.544
|
|
|
|
interleukin 2 biosynthetic process
|
GO:0042094 |
15 |
0.541
|
|
|
|
regulation of nitric oxide biosynthetic process
|
GO:0045428 |
18 |
0.540
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
61 |
0.536
|
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.534
|
Human |
|
|
positive regulation of neutrophil mediated cytotoxicity
|
GO:0070960 |
1 |
0.533
|
|
|
|
alpha beta t cell activation involved in immune response
|
GO:0002287 |
31 |
0.532
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.527
|
|
|
|
positive regulation of neutrophil mediated killing of symbiont cell
|
GO:0070961 |
1 |
0.520
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.517
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.514
|
|
|
|
acute phase response
|
GO:0006953 |
10 |
0.513
|
|
|
|
interleukin 10 secretion
|
GO:0072608 |
4 |
0.512
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.511
|
|
|
|
positive regulation of lymphocyte mediated immunity
|
GO:0002708 |
62 |
0.505
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.505
|
|
|
|
dna recombination
|
GO:0006310 |
92 |
0.503
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.499
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.494
|
|
|
|
detection of molecule of bacterial origin
|
GO:0032490 |
2 |
0.493
|
|
|
|
thymocyte migration
|
GO:0072679 |
2 |
0.492
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.491
|
Human |
|
|
leukocyte homeostasis
|
GO:0001776 |
79 |
0.484
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.484
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.480
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
52 |
0.468
|
Human |
|
|
response to interleukin 4
|
GO:0070670 |
23 |
0.467
|
|
|
|
interleukin 11 mediated signaling pathway
|
GO:0038154 |
2 |
0.462
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.461
|
Human |
|
|
tyrosine phosphorylation of stat protein
|
GO:0007260 |
23 |
0.457
|
Human |
|
|
granulocyte chemotaxis
|
GO:0071621 |
39 |
0.457
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.455
|
|
|
|
regulation of immune complex clearance by monocytes and macrophages
|
GO:0090264 |
2 |
0.451
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.450
|
Human |
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.441
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.441
|
Human |
|
|
positive regulation by symbiont of host immune response
|
GO:0052556 |
1 |
0.440
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.438
|
|
|
|
positive regulation of glial cell proliferation
|
GO:0060252 |
4 |
0.438
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.435
|
Human |
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.433
|
Human |
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.431
|
|
|
|
negative regulation of myoblast differentiation
|
GO:0045662 |
18 |
0.424
|
|
|
|
regulation of adrenergic receptor signaling pathway
|
GO:0071877 |
4 |
0.422
|
|
|
|
regulation of leukocyte mediated cytotoxicity
|
GO:0001910 |
38 |
0.421
|
|
|
|
t helper 2 cell cytokine production
|
GO:0035745 |
4 |
0.417
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.416
|
|
|
|
isotype switching to ige isotypes
|
GO:0048289 |
7 |
0.415
|
|
|
|
regulation of neutrophil mediated killing of fungus
|
GO:0070953 |
1 |
0.413
|
|
|
|
regulation of isotype switching
|
GO:0045191 |
22 |
0.410
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.410
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.409
|
|
|
|
regulation of acute inflammatory response
|
GO:0002673 |
27 |
0.407
|
Human |
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.406
|
Human |
|
|
positive regulation of natural killer cell activation
|
GO:0032816 |
15 |
0.401
|
|
|
|
placenta development
|
GO:0001890 |
140 |
0.397
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.397
|
|
|
|
negative regulation of interleukin 5 secretion
|
GO:2000663 |
1 |
0.396
|
|
|
|
regulation of insulin receptor signaling pathway
|
GO:0046626 |
21 |
0.385
|
|
|
|
alpha beta t cell proliferation
|
GO:0046633 |
21 |
0.376
|
|
|
|
alpha beta t cell differentiation involved in immune response
|
GO:0002293 |
30 |
0.373
|
|
|
|
necroptotic signaling pathway
|
GO:0097527 |
3 |
0.372
|
|
|
|
regulation of t helper 1 cell differentiation
|
GO:0045625 |
7 |
0.370
|
|
|
|
antimicrobial peptide secretion
|
GO:0002776 |
1 |
0.367
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.365
|
|
|
|
response to glucocorticoid
|
GO:0051384 |
20 |
0.361
|
Human |
|
|
cellular response to interleukin 4
|
GO:0071353 |
21 |
0.361
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.360
|
|
|
|
response to lithium ion
|
GO:0010226 |
10 |
0.359
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.358
|
|
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
39 |
0.358
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
26 |
0.358
|
|
|
|
regulation of fever generation
|
GO:0031620 |
6 |
0.356
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.356
|
|
|
|
isotype switching
|
GO:0045190 |
36 |
0.355
|
|
|
|
regulation of immunoglobulin mediated immune response
|
GO:0002889 |
37 |
0.353
|
|
|
|
regulation of protein oligomerization
|
GO:0032459 |
4 |
0.351
|
|
|
|
modification of morphology or physiology of other organism involved in symbiotic interaction
|
GO:0051817 |
16 |
0.349
|
|
|
|
positive regulation of natural killer cell mediated immunity
|
GO:0002717 |
16 |
0.349
|
|
|
|
t helper 1 cell differentiation
|
GO:0045063 |
13 |
0.344
|
|
|
|
regulation of cytokine production involved in immune response
|
GO:0002718 |
26 |
0.341
|
|
|
|
interleukin 6 biosynthetic process
|
GO:0042226 |
12 |
0.341
|
|
|
|
interleukin 27 mediated signaling pathway
|
GO:0070106 |
1 |
0.340
|
|
|
|
chemokine secretion
|
GO:0090195 |
5 |
0.333
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.330
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.330
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.328
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.326
|
Human |
|
|
rhythmic process
|
GO:0048511 |
174 |
0.326
|
|
|
|
regulation of interleukin 6 biosynthetic process
|
GO:0045408 |
11 |
0.325
|
|
|
|
regulation of syncytium formation by plasma membrane fusion
|
GO:0060142 |
23 |
0.324
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.322
|
|
|
|
alpha amino acid catabolic process
|
GO:1901606 |
18 |
0.322
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.314
|
Human |
|
|
peptide transport
|
GO:0015833 |
133 |
0.311
|
|
|
|
regulation of nucleotide binding oligomerization domain containing signaling pathway
|
GO:0070424 |
3 |
0.310
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.310
|
|
|
|
response to oxygen levels
|
GO:0070482 |
62 |
0.308
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.308
|
|
|
|
regulation of inflammatory response to antigenic stimulus
|
GO:0002861 |
21 |
0.307
|
|
|
|
positive regulation of apoptotic cell clearance
|
GO:2000427 |
3 |
0.307
|
|
|
|
b cell activation involved in immune response
|
GO:0002312 |
50 |
0.304
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.304
|
|
|
|
drug catabolic process
|
GO:0042737 |
2 |
0.300
|
|
|
|
positive regulation of fever generation
|
GO:0031622 |
6 |
0.299
|
|
|
|
regulation of heat generation
|
GO:0031650 |
8 |
0.299
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.299
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
87 |
0.298
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.297
|
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
30 |
0.295
|
|
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.294
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.294
|
|
|
|
positive regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903557 |
31 |
0.293
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.292
|
Human |
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.289
|
|
|
|
regulation of natural killer cell mediated cytotoxicity
|
GO:0042269 |
19 |
0.288
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
65 |
0.287
|
|
|
|
icosanoid metabolic process
|
GO:0006690 |
33 |
0.287
|
|
|
|
negative regulation of interleukin 5 production
|
GO:0032714 |
4 |
0.286
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.285
|
|
|
|
lateral line system development
|
GO:0048925 |
1 |
0.285
|
|
|
|
response to molecule of fungal origin
|
GO:0002238 |
4 |
0.283
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.282
|
|
|
|
response to amino acid
|
GO:0043200 |
37 |
0.278
|
|
|
|
interleukin 13 secretion
|
GO:0072611 |
2 |
0.276
|
|
|
|
modulation by symbiont of defense related host nitric oxide production
|
GO:0052163 |
1 |
0.275
|
|
|
|
isotype switching to igg isotypes
|
GO:0048291 |
10 |
0.274
|
|
|
|
immunoglobulin production
|
GO:0002377 |
73 |
0.274
|
Human |
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.271
|
Human |
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.271
|
Human |
|
|
hepatocyte growth factor receptor signaling pathway
|
GO:0048012 |
3 |
0.270
|
|
|
|
regulation of t helper cell differentiation
|
GO:0045622 |
14 |
0.270
|
|
|
|
nucleotide binding oligomerization domain containing 2 signaling pathway
|
GO:0070431 |
6 |
0.269
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.268
|
Human |
|
|
positive regulation of chemokine biosynthetic process
|
GO:0045080 |
6 |
0.267
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.267
|
|
|
|
regulation of interleukin 6 production
|
GO:0032675 |
55 |
0.267
|
Human |
|
|
production of molecular mediator involved in inflammatory response
|
GO:0002532 |
21 |
0.267
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.263
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.263
|
|
|
|
sterol metabolic process
|
GO:0016125 |
58 |
0.261
|
|
|
|
positive regulation of fever generation by positive regulation of prostaglandin secretion
|
GO:0071812 |
2 |
0.260
|
|
|
|
negative regulation of muscle contraction
|
GO:0045932 |
12 |
0.260
|
|
|
|
temperature homeostasis
|
GO:0001659 |
26 |
0.259
|
|
|
|
regulation of tyrosine phosphorylation of stat1 protein
|
GO:0042510 |
2 |
0.257
|
|
|
|
heat generation
|
GO:0031649 |
13 |
0.255
|
|
|
|
chemokine metabolic process
|
GO:0050755 |
10 |
0.254
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.254
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.254
|
Human |
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
71 |
0.253
|
|
|
|
b cell proliferation
|
GO:0042100 |
53 |
0.252
|
|
|
|
somatic cell dna recombination
|
GO:0016444 |
51 |
0.252
|
|
|
|
positive regulation of t helper 1 cell cytokine production
|
GO:2000556 |
1 |
0.249
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.247
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.247
|
|
|
|
response to interleukin 18
|
GO:0070673 |
4 |
0.243
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.240
|
|
|
|
regulation of neutrophil mediated killing of symbiont cell
|
GO:0070949 |
2 |
0.240
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.239
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.238
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.238
|
|
|
|
t helper 1 type immune response
|
GO:0042088 |
25 |
0.238
|
|
|
|
positive regulation of tyrosine phosphorylation of stat1 protein
|
GO:0042511 |
1 |
0.238
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.236
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.236
|
|
|
|
somatic diversification of immunoglobulins
|
GO:0016445 |
43 |
0.235
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.234
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.233
|
|
|
|
dendritic cell dendrite assembly
|
GO:0097026 |
2 |
0.231
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.231
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.229
|
|
|
|
negative regulation of odontogenesis of dentin containing tooth
|
GO:0042489 |
1 |
0.227
|
|
|
|
neutrophil mediated killing of bacterium
|
GO:0070944 |
6 |
0.223
|
|
|
|
leukocyte mediated cytotoxicity
|
GO:0001909 |
62 |
0.223
|
|
|
|
positive regulation of cell killing
|
GO:0031343 |
33 |
0.222
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.220
|
Human |
|
|
positive regulation of natural killer cell chemotaxis
|
GO:2000503 |
1 |
0.219
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.219
|
|
|
|
modification of morphology or physiology of other organism
|
GO:0035821 |
18 |
0.219
|
|
|
|
negative regulation of t helper 1 type immune response
|
GO:0002826 |
5 |
0.219
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.219
|
Human |
|
|
negative regulation of leukocyte proliferation
|
GO:0070664 |
46 |
0.217
|
|
|
|
regulation of defense response to bacterium
|
GO:1900424 |
3 |
0.216
|
|
|
|
positive regulation of brown fat cell differentiation
|
GO:0090336 |
4 |
0.214
|
|
|
|
acute inflammatory response
|
GO:0002526 |
41 |
0.213
|
Human |
|
|
negative regulation of alpha beta t cell activation
|
GO:0046636 |
18 |
0.211
|
|
|
|
positive regulation of neutrophil mediated killing of fungus
|
GO:0070965 |
1 |
0.209
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.207
|
|
|
|
response to interleukin 15
|
GO:0070672 |
3 |
0.206
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.206
|
Human |
|
|
positive regulation of membrane protein ectodomain proteolysis
|
GO:0051044 |
3 |
0.205
|
|
|
|
positive regulation of nucleotide binding oligomerization domain containing 1 signaling pathway
|
GO:0070430 |
1 |
0.204
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.203
|
|
|
|
positive regulation of synaptic plasticity
|
GO:0031915 |
4 |
0.203
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.202
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.202
|
|
|
|
positive regulation of hematopoietic stem cell proliferation
|
GO:1902035 |
2 |
0.201
|
|
|
|
chronic inflammatory response
|
GO:0002544 |
9 |
0.200
|
|
|
|
neutrophil migration
|
GO:1990266 |
37 |
0.198
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.197
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.194
|
Human |
|
|
positive regulation of activated t cell proliferation
|
GO:0042104 |
8 |
0.194
|
|
|
|
nucleotide binding oligomerization domain containing signaling pathway
|
GO:0070423 |
6 |
0.192
|
|
|
|
regulation of chronic inflammatory response
|
GO:0002676 |
7 |
0.192
|
|
|
|
regulation of myotube differentiation
|
GO:0010830 |
62 |
0.192
|
|
|
|
type i interferon signaling pathway
|
GO:0060337 |
10 |
0.191
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
74 |
0.191
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
91 |
0.189
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.186
|
|
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
41 |
0.186
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
121 |
0.186
|
|
|
|
regulation of alpha beta t cell proliferation
|
GO:0046640 |
18 |
0.185
|
|
|
|
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002823 |
23 |
0.183
|
|
|
|
response to corticosteroid
|
GO:0031960 |
20 |
0.183
|
Human |
|
|
negative regulation of t cell proliferation
|
GO:0042130 |
38 |
0.182
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.182
|
|
|
|
anion transport
|
GO:0006820 |
177 |
0.180
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.179
|
Human |
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.178
|
|
|
|
response to steroid hormone
|
GO:0048545 |
56 |
0.178
|
Human |
|
|
regulation of fatty acid transport
|
GO:2000191 |
10 |
0.178
|
|
|
|
negative regulation of b cell proliferation
|
GO:0030889 |
13 |
0.175
|
|
|
|
regulation of t helper 1 cell cytokine production
|
GO:2000554 |
1 |
0.175
|
|
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
21 |
0.175
|
|
|
|
natural killer cell mediated immunity
|
GO:0002228 |
29 |
0.174
|
|
|
|
defense response to virus
|
GO:0051607 |
68 |
0.174
|
Human |
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.174
|
|
|
|
interleukin 6 production
|
GO:0032635 |
58 |
0.174
|
Human |
|
|
regulation of membrane protein ectodomain proteolysis
|
GO:0051043 |
3 |
0.173
|
|
|
|
positive regulation of chemotaxis
|
GO:0050921 |
38 |
0.173
|
|
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
45 |
0.172
|
Human |
|
|
positive regulation of chronic inflammatory response
|
GO:0002678 |
4 |
0.171
|
|
|
|
regulation of interleukin 5 secretion
|
GO:2000662 |
2 |
0.171
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.171
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.169
|
|
|
|
icosanoid secretion
|
GO:0032309 |
12 |
0.168
|
|
|
|
positive regulation of isotype switching
|
GO:0045830 |
15 |
0.168
|
|
|
|
humoral immune response
|
GO:0006959 |
57 |
0.167
|
|
|
|
prostaglandin transport
|
GO:0015732 |
7 |
0.166
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.166
|
|
|
|
positive regulation of b cell activation
|
GO:0050871 |
49 |
0.166
|
Human |
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.165
|
|
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
41 |
0.164
|
|
|
|
keratinocyte migration
|
GO:0051546 |
3 |
0.163
|
|
|
|
positive regulation of immunoglobulin production
|
GO:0002639 |
28 |
0.162
|
Human |
|
|
organ regeneration
|
GO:0031100 |
2 |
0.161
|
|
|
|
interferon beta biosynthetic process
|
GO:0045350 |
4 |
0.161
|
|
|
|
positive regulation of transcription factor import into nucleus
|
GO:0042993 |
8 |
0.160
|
|
|
|
positive regulation of dna recombination
|
GO:0045911 |
17 |
0.159
|
|
|
|
negative regulation of syncytium formation by plasma membrane fusion
|
GO:0034242 |
5 |
0.159
|
|
|
|
positive regulation of interleukin 6 production
|
GO:0032755 |
37 |
0.157
|
Human |
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.157
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.156
|
|
|
|
type 2 immune response
|
GO:0042092 |
23 |
0.156
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.155
|
|
|
|
cholesterol metabolic process
|
GO:0008203 |
56 |
0.154
|
|
|
|
positive regulation of isotype switching to ige isotypes
|
GO:0048295 |
4 |
0.154
|
|
|
|
drug metabolic process
|
GO:0017144 |
4 |
0.153
|
|
|
|
positive regulation of monocyte chemotaxis
|
GO:0090026 |
2 |
0.152
|
|
|
|
positive regulation of muscle cell differentiation
|
GO:0051149 |
39 |
0.152
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.151
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.151
|
|
|
|
positive regulation of b cell proliferation
|
GO:0030890 |
24 |
0.151
|
|
|
|
neutrophil chemotaxis
|
GO:0030593 |
36 |
0.150
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.150
|
|
|
|
fibroblast growth factor production
|
GO:0090269 |
4 |
0.150
|
|
|
|
cdc42 protein signal transduction
|
GO:0032488 |
0 |
0.149
|
|
|
|
response to drug
|
GO:0042493 |
75 |
0.149
|
|
|
|
positive regulation of jak stat cascade
|
GO:0046427 |
22 |
0.149
|
Human |
|
|
positive regulation of syncytium formation by plasma membrane fusion
|
GO:0060143 |
17 |
0.148
|
|
|
|
interleukin 2 production
|
GO:0032623 |
33 |
0.147
|
|
|
|
regulation of hematopoietic stem cell proliferation
|
GO:1902033 |
3 |
0.146
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.146
|
|
|
|
regulation of natural killer cell differentiation
|
GO:0032823 |
11 |
0.146
|
|
|
|
positive regulation of acute inflammatory response
|
GO:0002675 |
16 |
0.145
|
Human |
|
|
positive regulation of b cell chemotaxis
|
GO:2000538 |
2 |
0.145
|
|
|
|
cytokine production involved in immune response
|
GO:0002367 |
34 |
0.143
|
|
|
|
t helper cell differentiation
|
GO:0042093 |
28 |
0.143
|
|
|
|
positive regulation of type 2 immune response
|
GO:0002830 |
9 |
0.141
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.140
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.139
|
|
|
|
mammary gland lobule development
|
GO:0061377 |
22 |
0.138
|
|
|
|
positive regulation of neuron apoptotic process
|
GO:0043525 |
25 |
0.138
|
|
|
|
regulation of neuron death
|
GO:1901214 |
134 |
0.138
|
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.137
|
|
|
|
modulation by symbiont of host immune response
|
GO:0052553 |
1 |
0.137
|
|
|
|
prostaglandin metabolic process
|
GO:0006693 |
11 |
0.136
|
|
|
|
amino acid transport
|
GO:0006865 |
61 |
0.135
|
|
|
|
innate immune response activating cell surface receptor signaling pathway
|
GO:0002220 |
4 |
0.135
|
|
|
|
transcription factor import into nucleus
|
GO:0042991 |
26 |
0.135
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.135
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.134
|
|
|
|
nitric oxide biosynthetic process
|
GO:0006809 |
25 |
0.134
|
|
|
|
cellular response to interleukin 1
|
GO:0071347 |
8 |
0.133
|
|
|
|
regulation of eosinophil migration
|
GO:2000416 |
2 |
0.132
|
|
|
|
regulation of fibroblast growth factor production
|
GO:0090270 |
4 |
0.131
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.131
|
Human |
|
|
positive regulation of immune complex clearance by monocytes and macrophages
|
GO:0090265 |
2 |
0.130
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
40 |
0.130
|
|
|
|
regulation of isotype switching to igg isotypes
|
GO:0048302 |
10 |
0.130
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.129
|
|
|
|
positive regulation of nitric oxide biosynthetic process
|
GO:0045429 |
14 |
0.128
|
|
|
|
regulation of skeletal muscle fiber development
|
GO:0048742 |
36 |
0.128
|
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
50 |
0.127
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.127
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.126
|
|
|
|
cytokine secretion involved in immune response
|
GO:0002374 |
6 |
0.126
|
|
|
|
tyrosine phosphorylation of stat3 protein
|
GO:0042503 |
12 |
0.126
|
Human |
|
|
angiogenesis
|
GO:0001525 |
201 |
0.125
|
|
|
|
positive regulation of interleukin 1 secretion
|
GO:0050716 |
14 |
0.125
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.124
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.123
|
|
|
|
antibiotic transport
|
GO:0042891 |
1 |
0.123
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.122
|
|
|
|
cellular response to inorganic substance
|
GO:0071241 |
37 |
0.120
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.120
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.119
|
Human |
|
|
t cell activation involved in immune response
|
GO:0002286 |
43 |
0.119
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.119
|
|
|
|
mast cell proliferation
|
GO:0070662 |
4 |
0.119
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.118
|
|
|
|
organic acid transport
|
GO:0015849 |
101 |
0.118
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
79 |
0.118
|
|
|
|
tumor necrosis factor mediated signaling pathway
|
GO:0033209 |
13 |
0.117
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.116
|
|
|
|
positive regulation of interleukin 18 production
|
GO:0032741 |
2 |
0.116
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
97 |
0.115
|
|
|
|
interleukin 1 mediated signaling pathway
|
GO:0070498 |
4 |
0.115
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
65 |
0.114
|
Human |
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
42 |
0.114
|
|
|
|
granulocyte migration
|
GO:0097530 |
43 |
0.113
|
|
|
|
carbohydrate homeostasis
|
GO:0033500 |
128 |
0.113
|
|
|
|
regulation of interleukin 13 secretion
|
GO:2000665 |
2 |
0.113
|
|
|
|
positive regulation of mitotic cell cycle
|
GO:0045931 |
41 |
0.112
|
|
|
|
cellular response to arsenic containing substance
|
GO:0071243 |
4 |
0.112
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.111
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.111
|
|
|
|
jak stat cascade involved in growth hormone signaling pathway
|
GO:0060397 |
4 |
0.110
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.109
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.108
|
|
|
|
negative regulation of adaptive immune response
|
GO:0002820 |
25 |
0.108
|
|
|
|
glucose homeostasis
|
GO:0042593 |
128 |
0.108
|
|
|
|
t helper 1 cell cytokine production
|
GO:0035744 |
1 |
0.108
|
|
|
|
regulation of natural killer cell proliferation
|
GO:0032817 |
2 |
0.108
|
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
77 |
0.107
|
|
|
|
positive regulation of myoblast differentiation
|
GO:0045663 |
8 |
0.106
|
|
|
|
negative regulation of chronic inflammatory response
|
GO:0002677 |
3 |
0.106
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.105
|
|
|
|
positive regulation of dendritic cell dendrite assembly
|
GO:2000549 |
1 |
0.105
|
|
|
|
regulation of t helper 1 type immune response
|
GO:0002825 |
17 |
0.105
|
|
|
|
negative regulation of t helper 2 cell differentiation
|
GO:0045629 |
4 |
0.105
|
|
|
|
cell surface pattern recognition receptor signaling pathway
|
GO:0002752 |
2 |
0.104
|
|
|
|
regulation of organic acid transport
|
GO:0032890 |
16 |
0.104
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.104
|
|
|
|
protein import
|
GO:0017038 |
101 |
0.104
|
|
|
|
g protein coupled receptor signaling pathway coupled to cgmp nucleotide second messenger
|
GO:0007199 |
1 |
0.104
|
|
|
|
response to interleukin 6
|
GO:0070741 |
10 |
0.103
|
|
|
|
positive regulation of cytokine secretion involved in immune response
|
GO:0002741 |
2 |
0.103
|
|
|
|
negative regulation of macrophage apoptotic process
|
GO:2000110 |
3 |
0.103
|
|
|
|
regulation of lipopolysaccharide mediated signaling pathway
|
GO:0031664 |
9 |
0.102
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.102
|
|
|
|
positive regulation of organic acid transport
|
GO:0032892 |
11 |
0.102
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.102
|
|
|
|
positive regulation of chemokine secretion
|
GO:0090197 |
4 |
0.102
|
|
|
|
response to low density lipoprotein particle
|
GO:0055098 |
2 |
0.102
|
|
|
|
regulation of fever generation by regulation of prostaglandin secretion
|
GO:0071810 |
2 |
0.101
|
|
|
|
l amino acid transport
|
GO:0015807 |
32 |
0.101
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.101
|
|
|
|
regulation of response to cytokine stimulus
|
GO:0060759 |
23 |
0.100
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.100
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.100
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
60 |
0.099
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.099
|
|
|
|
regulation of immunoglobulin secretion
|
GO:0051023 |
12 |
0.099
|
Human |
|
|
regulation of vasculature development
|
GO:1901342 |
88 |
0.099
|
|
|
|
regulation of neutrophil mediated killing of bacterium
|
GO:0070950 |
1 |
0.099
|
|
|
|
antimicrobial peptide biosynthetic process
|
GO:0002777 |
2 |
0.099
|
|
