|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.995
|
Human |
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.995
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.992
|
Human |
|
|
activation of mapk activity involved in innate immune response
|
GO:0035419 |
2 |
0.992
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.989
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.980
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.980
|
Human Mouse |
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.973
|
Human Mouse |
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
61 |
0.970
|
Mouse |
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.968
|
Human Mouse |
|
|
tyrosine phosphorylation of stat3 protein
|
GO:0042503 |
12 |
0.967
|
Human |
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
36 |
0.966
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.948
|
|
|
|
myeloid cell apoptotic process
|
GO:0033028 |
22 |
0.944
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.940
|
|
|
|
leukocyte homeostasis
|
GO:0001776 |
79 |
0.931
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.913
|
Human Mouse |
|
|
activation of janus kinase activity
|
GO:0042976 |
2 |
0.910
|
|
|
|
regulation of mast cell apoptotic process
|
GO:0033025 |
5 |
0.904
|
|
|
|
cellular response to interleukin 6
|
GO:0071354 |
9 |
0.901
|
Human Rat |
|
|
response to interleukin 15
|
GO:0070672 |
3 |
0.889
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.888
|
|
|
|
lactation
|
GO:0007595 |
25 |
0.881
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.880
|
|
|
|
regulation of tyrosine phosphorylation of stat protein
|
GO:0042509 |
20 |
0.878
|
Human |
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.878
|
|
|
|
regulation of tyrosine phosphorylation of stat1 protein
|
GO:0042510 |
2 |
0.861
|
Human |
|
|
regulation of tyrosine phosphorylation of stat3 protein
|
GO:0042516 |
10 |
0.859
|
Human |
|
|
t helper 1 cell differentiation
|
GO:0045063 |
13 |
0.853
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.853
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.850
|
|
|
|
response to host defenses
|
GO:0052200 |
3 |
0.847
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.837
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.829
|
Human |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.826
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.825
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.825
|
|
|
|
organ regeneration
|
GO:0031100 |
2 |
0.823
|
|
|
|
jak stat cascade involved in growth hormone signaling pathway
|
GO:0060397 |
4 |
0.811
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.807
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
56 |
0.806
|
|
|
|
positive regulation of glial cell proliferation
|
GO:0060252 |
4 |
0.801
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.800
|
|
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
52 |
0.792
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.790
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.784
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
53 |
0.782
|
|
|
|
cellular amide metabolic process
|
GO:0043603 |
58 |
0.781
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.780
|
Mouse |
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.778
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.777
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.775
|
Human |
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.769
|
Mouse |
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.766
|
Zebrafish |
|
|
activation of cysteine type endopeptidase activity involved in apoptotic signaling pathway
|
GO:0097296 |
2 |
0.765
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.760
|
|
|
|
tyrosine phosphorylation of stat1 protein
|
GO:0042508 |
3 |
0.757
|
Human |
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.756
|
Mouse |
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.747
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.742
|
Rat |
|
|
mast cell apoptotic process
|
GO:0033024 |
5 |
0.739
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.731
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.731
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.729
|
|
|
|
regulation of cd4 positive alpha beta t cell activation
|
GO:2000514 |
24 |
0.728
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
51 |
0.727
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.726
|
Mouse |
|
|
regulation of alpha beta t cell differentiation
|
GO:0046637 |
35 |
0.725
|
|
|
|
retina morphogenesis in camera type eye
|
GO:0060042 |
45 |
0.717
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.717
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.715
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.709
|
|
|
|
natural killer cell proliferation
|
GO:0001787 |
3 |
0.708
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.707
|
|
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.705
|
|
|
|
positive t cell selection
|
GO:0043368 |
23 |
0.705
|
|
|
|
mast cell proliferation
|
GO:0070662 |
4 |
0.704
|
|
|
|
radial glia guided migration of purkinje cell
|
GO:0021942 |
6 |
0.703
|
|
|
|
negative regulation of t helper 1 cell differentiation
|
GO:0045626 |
3 |
0.702
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
82 |
0.697
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.696
|
Mouse |
|
|
lipid homeostasis
|
GO:0055088 |
63 |
0.694
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.690
|
Mouse |
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.690
|
|
|
|
cellular response to amino acid stimulus
|
GO:0071230 |
29 |
0.679
|
|
|
|
positive regulation of interleukin 2 biosynthetic process
|
GO:0045086 |
8 |
0.679
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.674
|
Rat |
|
|
regulation of type 2 immune response
|
GO:0002828 |
18 |
0.674
|
Mouse |
|
|
nuclear transport
|
GO:0051169 |
139 |
0.671
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.665
|
|
|
|
regeneration
|
GO:0031099 |
38 |
0.661
|
Zebrafish |
|
|
negative regulation of inflammatory response to antigenic stimulus
|
GO:0002862 |
10 |
0.659
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
52 |
0.657
|
|
|
|
negative regulation of lymphocyte differentiation
|
GO:0045620 |
32 |
0.651
|
|
|
|
regulation of smad protein import into nucleus
|
GO:0060390 |
3 |
0.651
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.650
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.649
|
|
|
|
somatic diversification of immunoglobulins involved in immune response
|
GO:0002208 |
36 |
0.640
|
Mouse |
|
|
interleukin 6 mediated signaling pathway
|
GO:0070102 |
6 |
0.637
|
Human Rat |
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
74 |
0.632
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.629
|
|
|
|
regulation of mast cell proliferation
|
GO:0070666 |
4 |
0.620
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.616
|
Human Mouse |
|
|
response to interleukin 6
|
GO:0070741 |
10 |
0.609
|
Human Rat |
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.608
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.608
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.608
|
|
|
|
isotype switching to ige isotypes
|
GO:0048289 |
7 |
0.601
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.601
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.597
|
|
|
|
type i interferon signaling pathway
|
GO:0060337 |
10 |
0.596
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.588
|
|
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
41 |
0.588
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.587
|
|
|
|
macrophage fusion
|
GO:0034238 |
3 |
0.586
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.578
|
|
|
|
citrate metabolic process
|
GO:0006101 |
3 |
0.574
|
|
|
|
t helper cell differentiation
|
GO:0042093 |
28 |
0.571
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.568
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.568
|
|
|
|
lateral line system development
|
GO:0048925 |
1 |
0.564
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.563
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.563
|
|
|
|
negative regulation of alpha beta t cell activation
|
GO:0046636 |
18 |
0.562
|
|
|
|
response to oxygen levels
|
GO:0070482 |
62 |
0.562
|
|
|
|
regulation of activation of jak2 kinase activity
|
GO:0010534 |
1 |
0.560
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.554
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.546
|
|
|
|
somatic recombination of immunoglobulin gene segments
|
GO:0016447 |
42 |
0.545
|
Mouse |
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
34 |
0.544
|
|
|
|
cd4 positive alpha beta t cell lineage commitment
|
GO:0043373 |
6 |
0.543
|
|
|
|
progesterone metabolic process
|
GO:0042448 |
4 |
0.540
|
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.539
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.534
|
|
|
|
positive regulation of tyrosine phosphorylation of stat3 protein
|
GO:0042517 |
7 |
0.532
|
Human |
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.531
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.527
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.526
|
|
|
|
nuclear import
|
GO:0051170 |
95 |
0.520
|
|
|
|
response to amino acid
|
GO:0043200 |
37 |
0.517
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
59 |
0.515
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.514
|
Mouse |
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway
|
GO:2001269 |
3 |
0.514
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.514
|
|
|
|
somatic diversification of immunoglobulins
|
GO:0016445 |
43 |
0.514
|
Mouse |
|
|
positive regulation of mast cell proliferation
|
GO:0070668 |
3 |
0.510
|
|
|
|
t helper 1 type immune response
|
GO:0042088 |
25 |
0.509
|
Mouse |
|
|
regulation of system process
|
GO:0044057 |
200 |
0.507
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.505
|
|
|
|
response to corticosteroid
|
GO:0031960 |
20 |
0.505
|
|
|
|
positive regulation of cell proliferation involved in heart valve morphogenesis
|
GO:0003251 |
1 |
0.493
|
|
|
|
regulation of interleukin 8 production
|
GO:0032677 |
3 |
0.493
|
|
|
|
positive regulation of epidermal growth factor activated receptor activity
|
GO:0045741 |
2 |
0.489
|
|
|
|
bone morphogenesis
|
GO:0060349 |
78 |
0.489
|
|
|
|
t helper 1 cell lineage commitment
|
GO:0002296 |
2 |
0.486
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.480
|
|
|
|
chemokine production
|
GO:0032602 |
34 |
0.480
|
|
|
|
negative regulation of lymphocyte apoptotic process
|
GO:0070229 |
24 |
0.478
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
61 |
0.466
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.463
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.462
|
Mouse |
|
|
response to decreased oxygen levels
|
GO:0036293 |
59 |
0.460
|
|
|
|
regulation of insulin receptor signaling pathway
|
GO:0046626 |
21 |
0.459
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.453
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.451
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.449
|
Mouse |
|
|
negative regulation of t cell differentiation
|
GO:0045581 |
23 |
0.445
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.445
|
|
|
|
negative regulation of type 2 immune response
|
GO:0002829 |
8 |
0.443
|
Mouse |
|
|
mucopolysaccharide metabolic process
|
GO:1903510 |
25 |
0.442
|
|
|
|
regulation of natural killer cell differentiation
|
GO:0032823 |
11 |
0.440
|
|
|
|
epidermal growth factor receptor signaling pathway
|
GO:0007173 |
28 |
0.440
|
|
|
|
positive regulation of alpha beta t cell differentiation
|
GO:0046638 |
28 |
0.434
|
|
|
|
response to granulocyte macrophage colony stimulating factor
|
GO:0097012 |
3 |
0.434
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.431
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.430
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.427
|
Mouse |
|
|
negative regulation of tyrosine phosphorylation of stat protein
|
GO:0042532 |
3 |
0.424
|
|
|
|
hindbrain radial glia guided cell migration
|
GO:0021932 |
12 |
0.422
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.421
|
|
|
|
glucose homeostasis
|
GO:0042593 |
128 |
0.418
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.415
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.413
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.413
|
|
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.411
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.408
|
|
|
|
ovulation cycle
|
GO:0042698 |
59 |
0.408
|
|
|
|
t helper cell lineage commitment
|
GO:0002295 |
6 |
0.400
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.399
|
|
|
|
negative regulation of cellular response to growth factor stimulus
|
GO:0090288 |
46 |
0.399
|
|
|
|
luteinization
|
GO:0001553 |
8 |
0.398
|
|
|
|
positive regulation of membrane protein ectodomain proteolysis
|
GO:0051044 |
3 |
0.398
|
|
|
|
regulation of notch signaling pathway
|
GO:0008593 |
35 |
0.397
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.396
|
Mouse |
|
|
phagocytosis
|
GO:0006909 |
66 |
0.394
|
|
|
|
mechanoreceptor differentiation
|
GO:0042490 |
67 |
0.394
|
|
|
|
regulation of isotype switching to ige isotypes
|
GO:0048293 |
7 |
0.391
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.388
|
Mouse |
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.386
|
Mouse |
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.381
|
|
|
|
modulation by virus of host morphology or physiology
|
GO:0019048 |
3 |
0.381
|
|
|
|
regulation of neuron projection regeneration
|
GO:0070570 |
7 |
0.374
|
Zebrafish |
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
11 |
0.373
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
116 |
0.373
|
|
|
|
negative regulation of t helper 2 cell differentiation
|
GO:0045629 |
4 |
0.373
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
65 |
0.372
|
|
|
|
fibronectin dependent thymocyte migration
|
GO:0072681 |
1 |
0.371
|
|
|
|
t cell lineage commitment
|
GO:0002360 |
13 |
0.370
|
|
|
|
regulation of activation of janus kinase activity
|
GO:0010533 |
1 |
0.368
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.367
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.367
|
Mouse |
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.367
|
|
|
|
t cell apoptotic process
|
GO:0070231 |
39 |
0.365
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway
|
GO:2001267 |
4 |
0.364
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.363
|
|
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.362
|
|
|
|
connective tissue development
|
GO:0061448 |
179 |
0.360
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.355
|
Human |
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.355
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.354
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.352
|
Mouse |
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.351
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.351
|
|
|
|
positive regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0045737 |
6 |
0.349
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.348
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.347
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.346
|
|
|
|
positive regulation of chemotaxis
|
GO:0050921 |
38 |
0.339
|
|
|
|
regulation of natural killer cell proliferation
|
GO:0032817 |
2 |
0.337
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.335
|
|
|
|
protein import
|
GO:0017038 |
101 |
0.334
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.333
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.333
|
Mouse |
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.332
|
|
|
|
regulation of t helper cell differentiation
|
GO:0045622 |
14 |
0.331
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.329
|
|
|
|
positive regulation of apoptotic process involved in mammary gland involution
|
GO:0060058 |
4 |
0.329
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.329
|
Rat |
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.328
|
|
|
|
prolactin signaling pathway
|
GO:0038161 |
5 |
0.325
|
|
|
|
negative regulation of tyrosine phosphorylation of stat3 protein
|
GO:0042518 |
1 |
0.325
|
|
|
|
positive regulation of isotype switching to ige isotypes
|
GO:0048295 |
4 |
0.324
|
|
|
|
regulation of peptidyl serine phosphorylation
|
GO:0033135 |
39 |
0.323
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.319
|
|
|
|
negative regulation of blood vessel endothelial cell migration
|
GO:0043537 |
3 |
0.319
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.318
|
|
|
|
creatinine metabolic process
|
GO:0046449 |
3 |
0.317
|
|
|
|
cellular response to growth hormone stimulus
|
GO:0071378 |
7 |
0.316
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.315
|
|
|
|
regulation of b cell differentiation
|
GO:0045577 |
23 |
0.315
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.314
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.314
|
|
|
|
cell growth involved in cardiac muscle cell development
|
GO:0061049 |
3 |
0.311
|
|
|
|
detection of chemical stimulus involved in sensory perception of taste
|
GO:0050912 |
3 |
0.310
|
|
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
61 |
0.310
|
Mouse |
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.310
|
Mouse |
|
|
response to glucocorticoid
|
GO:0051384 |
20 |
0.309
|
|
|
|
t cell activation involved in immune response
|
GO:0002286 |
43 |
0.309
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.309
|
Human |
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.307
|
|
|
|
interleukin 4 mediated signaling pathway
|
GO:0035771 |
2 |
0.304
|
|
|
|
female sex differentiation
|
GO:0046660 |
84 |
0.301
|
|
|
|
regulation of chemokine production
|
GO:0032642 |
30 |
0.294
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
62 |
0.293
|
|
|
|
cellular response to granulocyte macrophage colony stimulating factor stimulus
|
GO:0097011 |
3 |
0.293
|
|
|
|
negative regulation of interferon gamma mediated signaling pathway
|
GO:0060336 |
1 |
0.292
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.290
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.290
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
65 |
0.289
|
Mouse |
|
|
negative regulation of alpha beta t cell differentiation
|
GO:0046639 |
12 |
0.288
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.287
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.286
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.286
|
|
|
|
isoleucine metabolic process
|
GO:0006549 |
4 |
0.286
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.285
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
55 |
0.283
|
|
|
|
positive regulation of lymphocyte differentiation
|
GO:0045621 |
61 |
0.281
|
|
|
|
protein kinase c activating g protein coupled receptor signaling pathway
|
GO:0007205 |
4 |
0.275
|
|
|
|
prostate gland morphogenesis
|
GO:0060512 |
32 |
0.272
|
|
|
|
bone development
|
GO:0060348 |
120 |
0.271
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.271
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
43 |
0.271
|
|
|
|
cartilage development
|
GO:0051216 |
140 |
0.269
|
|
|
|
isotype switching
|
GO:0045190 |
36 |
0.269
|
Mouse |
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
92 |
0.268
|
|
|
|
replacement ossification
|
GO:0036075 |
26 |
0.265
|
|
|
|
positive regulation of activated t cell proliferation
|
GO:0042104 |
8 |
0.265
|
|
|
|
regulation of heart contraction
|
GO:0008016 |
77 |
0.264
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
59 |
0.262
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.262
|
Zebrafish |
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.262
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.261
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
3 |
0.261
|
|
|
|
organ or tissue specific immune response
|
GO:0002251 |
13 |
0.259
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.259
|
Mouse |
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.259
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.257
|
|
|
|
mast cell homeostasis
|
GO:0033023 |
5 |
0.257
|
|
|
|
carbohydrate homeostasis
|
GO:0033500 |
128 |
0.257
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.255
|
|
|
|
regulation of transcription factor import into nucleus
|
GO:0042990 |
24 |
0.254
|
|
|
|
negative regulation of intracellular transport
|
GO:0032387 |
38 |
0.253
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.252
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.251
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.251
|
|
|
|
positive regulation of b cell differentiation
|
GO:0045579 |
13 |
0.250
|
|
|
|
type 2 immune response
|
GO:0042092 |
23 |
0.250
|
Mouse |
|
|
protein targeting
|
GO:0006605 |
143 |
0.249
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.248
|
|
|
|
regulation of t helper 1 cell differentiation
|
GO:0045625 |
7 |
0.248
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.247
|
|
|
|
t helper 2 cell differentiation
|
GO:0045064 |
12 |
0.245
|
|
|
|
alpha beta t cell differentiation involved in immune response
|
GO:0002293 |
30 |
0.245
|
|
|
|
negative regulation of leukocyte apoptotic process
|
GO:2000107 |
31 |
0.245
|
|
|
|
positive regulation of gamma delta t cell differentiation
|
GO:0045588 |
6 |
0.244
|
|
|
|
regulation of lymphocyte apoptotic process
|
GO:0070228 |
41 |
0.244
|
|
|
|
positive regulation of inflammatory response
|
GO:0050729 |
47 |
0.242
|
|
|
|
salivary gland development
|
GO:0007431 |
37 |
0.240
|
|
|
|
positive regulation of jak stat cascade
|
GO:0046427 |
22 |
0.240
|
Human |
|
|
ripoptosome assembly involved in necroptotic process
|
GO:1901026 |
6 |
0.239
|
|
|
|
regulation of myeloid cell apoptotic process
|
GO:0033032 |
19 |
0.239
|
|
|
|
extrinsic apoptotic signaling pathway via death domain receptors
|
GO:0008625 |
34 |
0.239
|
|
|
|
aminoglycan metabolic process
|
GO:0006022 |
34 |
0.238
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.236
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.235
|
Mouse |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.233
|
Human |
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.233
|
|
|
|
valine metabolic process
|
GO:0006573 |
4 |
0.233
|
|
|
|
positive regulation of natural killer cell proliferation
|
GO:0032819 |
2 |
0.233
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.232
|
|
|
|
necroptotic process
|
GO:0070266 |
21 |
0.230
|
|
|
|
collagen biosynthetic process
|
GO:0032964 |
7 |
0.230
|
|
|
|
body fluid secretion
|
GO:0007589 |
53 |
0.230
|
|
|
|
t cell selection
|
GO:0045058 |
34 |
0.230
|
|
|
|
negative regulation of inflammatory response
|
GO:0050728 |
61 |
0.229
|
|
|
|
positive regulation of b cell mediated immunity
|
GO:0002714 |
26 |
0.229
|
|
|
|
collagen metabolic process
|
GO:0032963 |
17 |
0.227
|
|
|
|
mesenchyme development
|
GO:0060485 |
152 |
0.226
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.226
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
64 |
0.223
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
49 |
0.223
|
|
|
|
dna recombination
|
GO:0006310 |
92 |
0.222
|
Mouse |
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.222
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.222
|
|
|
|
antibacterial peptide production
|
GO:0002778 |
2 |
0.220
|
|
|
|
positive regulation of notch signaling pathway
|
GO:0045747 |
18 |
0.219
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.219
|
|
|
|
taurine metabolic process
|
GO:0019530 |
4 |
0.219
|
|
|
|
immunoglobulin production
|
GO:0002377 |
73 |
0.218
|
Mouse |
|
|
tyrosine phosphorylation of stat protein
|
GO:0007260 |
23 |
0.218
|
Human |
|
|
muscle system process
|
GO:0003012 |
141 |
0.217
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.216
|
|
|
|
keratinocyte migration
|
GO:0051546 |
3 |
0.215
|
|
|
|
negative regulation of interleukin 8 production
|
GO:0032717 |
1 |
0.215
|
|
|
|
extracellular structure organization
|
GO:0043062 |
148 |
0.214
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
33 |
0.214
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.214
|
Human |
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.213
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.212
|
|
|
|
biomineral tissue development
|
GO:0031214 |
64 |
0.211
|
|
|
|
positive regulation of tyrosine phosphorylation of stat1 protein
|
GO:0042511 |
1 |
0.210
|
Human |
|
|
allantoin metabolic process
|
GO:0000255 |
3 |
0.210
|
|
|
|
negative regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030512 |
26 |
0.210
|
|
|
|
neutrophil apoptotic process
|
GO:0001781 |
3 |
0.209
|
|
|
|
regulation of jak stat cascade
|
GO:0046425 |
34 |
0.209
|
Human |
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.207
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.207
|
Zebrafish |
|
|
transcription factor import into nucleus
|
GO:0042991 |
26 |
0.206
|
|
|
|
muscle cell proliferation
|
GO:0033002 |
52 |
0.206
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.203
|
|
|
|
cellular response to x ray
|
GO:0071481 |
2 |
0.203
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.202
|
|
|
|
development of secondary male sexual characteristics
|
GO:0046544 |
3 |
0.201
|
|
|
|
cellular lactam metabolic process
|
GO:0072338 |
3 |
0.201
|
|
|
|
prostate gland development
|
GO:0030850 |
48 |
0.201
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.199
|
|
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.199
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.199
|
|
|
|
sphingolipid metabolic process
|
GO:0006665 |
45 |
0.198
|
|
|
|
regulation of b cell mediated immunity
|
GO:0002712 |
37 |
0.195
|
Mouse |
|
|
positive regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014068 |
20 |
0.194
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
87 |
0.194
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.194
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.193
|
|
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.192
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
42 |
0.191
|
|
|
|
regulation of t helper 2 cell differentiation
|
GO:0045628 |
8 |
0.190
|
|
|
|
regulation of tight junction assembly
|
GO:2000810 |
2 |
0.190
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.189
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.188
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
80 |
0.188
|
|
|
|
innate immune response in mucosa
|
GO:0002227 |
3 |
0.188
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.187
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.187
|
|
|
|
cd4 positive or cd8 positive alpha beta t cell lineage commitment
|
GO:0043369 |
8 |
0.187
|
|
|
|
regulation of t cell anergy
|
GO:0002667 |
4 |
0.187
|
|
|
|
positive regulation of peptidyl serine phosphorylation
|
GO:0033138 |
25 |
0.184
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.184
|
|
|
|
response to defenses of other organism involved in symbiotic interaction
|
GO:0052173 |
3 |
0.184
|
|
|
|
negative regulation of glycolytic process
|
GO:0045820 |
4 |
0.183
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.183
|
Mouse |
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.182
|
|
|
|
positive regulation of nucleotide biosynthetic process
|
GO:0030810 |
26 |
0.182
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.182
|
|
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
59 |
0.180
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
107 |
0.180
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.180
|
|
|
|
regulation of t cell apoptotic process
|
GO:0070232 |
28 |
0.179
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.179
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
144 |
0.178
|
|
|
|
placenta development
|
GO:0001890 |
140 |
0.178
|
|
|
|
creatine metabolic process
|
GO:0006600 |
4 |
0.177
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.177
|
|
|
|
appendage development
|
GO:0048736 |
166 |
0.177
|
|
|
|
aminoglycan catabolic process
|
GO:0006026 |
3 |
0.176
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.175
|
|
|
|
response to interferon gamma
|
GO:0034341 |
34 |
0.174
|
|
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
40 |
0.174
|
|
|
|
negative regulation of reactive oxygen species biosynthetic process
|
GO:1903427 |
0 |
0.173
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.173
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.173
|
|
|
|
cd4 positive alpha beta t cell differentiation involved in immune response
|
GO:0002294 |
28 |
0.170
|
|
|
|
prostate gland epithelium morphogenesis
|
GO:0060740 |
31 |
0.170
|
|
|
|
labyrinthine layer morphogenesis
|
GO:0060713 |
21 |
0.170
|
|
|
|
regulation of fibronectin dependent thymocyte migration
|
GO:2000413 |
1 |
0.169
|
|
|
|
positive regulation of immunoglobulin production
|
GO:0002639 |
28 |
0.168
|
|
|
|
t cell differentiation involved in immune response
|
GO:0002292 |
30 |
0.168
|
|
|
|
positive regulation of atp biosynthetic process
|
GO:2001171 |
2 |
0.167
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.167
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
|
GO:1902043 |
13 |
0.166
|
|
|
|
endocrine system development
|
GO:0035270 |
98 |
0.166
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.165
|
|
|
|
response to interleukin 2
|
GO:0070669 |
2 |
0.165
|
|
|
|
interleukin 2 biosynthetic process
|
GO:0042094 |
15 |
0.165
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.164
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
73 |
0.164
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
27 |
0.163
|
|
|
|
regulation of interleukin 2 production
|
GO:0032663 |
28 |
0.163
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.163
|
|
|
|
regulation of acute inflammatory response
|
GO:0002673 |
27 |
0.163
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.162
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.162
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.162
|
|
|
|
positive regulation of alkaline phosphatase activity
|
GO:0010694 |
3 |
0.161
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.161
|
Zebrafish |
|
|
response to inactivity
|
GO:0014854 |
4 |
0.161
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.160
|
|
|
|
nitric oxide mediated signal transduction
|
GO:0007263 |
4 |
0.160
|
|
|
|
regulation of membrane protein ectodomain proteolysis
|
GO:0051043 |
3 |
0.160
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.159
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.158
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.158
|
|
|
|
hormone mediated signaling pathway
|
GO:0009755 |
23 |
0.158
|
|
|
|
endochondral bone morphogenesis
|
GO:0060350 |
50 |
0.157
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
119 |
0.157
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.156
|
|
|
|
somatic cell dna recombination
|
GO:0016444 |
51 |
0.156
|
Mouse |
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.155
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
96 |
0.155
|
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.155
|
|
|
|
inflammatory response to antigenic stimulus
|
GO:0002437 |
30 |
0.155
|
|
|
|
liver development
|
GO:0001889 |
66 |
0.154
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
91 |
0.154
|
|
|
|
prevention of polyspermy
|
GO:0060468 |
4 |
0.154
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
78 |
0.154
|
|
|
|
interferon gamma mediated signaling pathway
|
GO:0060333 |
5 |
0.154
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
68 |
0.153
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.153
|
|
|
|
negative regulation of intracellular protein transport
|
GO:0090317 |
27 |
0.152
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.152
|
|
|
|
regulation of eosinophil migration
|
GO:2000416 |
2 |
0.152
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.151
|
|
|
|
negative regulation of neuron differentiation
|
GO:0045665 |
101 |
0.150
|
|
|
|
defense response to gram negative bacterium
|
GO:0050829 |
28 |
0.147
|
|
|
|
interleukin 2 mediated signaling pathway
|
GO:0038110 |
2 |
0.147
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.147
|
|
|
|
astrocyte differentiation
|
GO:0048708 |
43 |
0.146
|
|
|
|
positive regulation of cd4 positive alpha beta t cell differentiation
|
GO:0043372 |
14 |
0.146
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
73 |
0.146
|
|
|
|
positive regulation of smad protein import into nucleus
|
GO:0060391 |
2 |
0.145
|
|
|
|
positive regulation of mast cell differentiation
|
GO:0060376 |
1 |
0.145
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.144
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.144
|
|
|
|
regulation of thymocyte apoptotic process
|
GO:0070243 |
14 |
0.143
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.143
|
|
|
|
negative regulation of nik nf kappab signaling
|
GO:1901223 |
2 |
0.142
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.142
|
|
