|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.932
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.904
|
Mouse |
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.790
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.789
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.776
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.764
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.748
|
|
|
|
detection of yeast
|
GO:0001879 |
2 |
0.743
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.725
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.708
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.627
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.619
|
|
|
|
stimulatory c type lectin receptor signaling pathway
|
GO:0002223 |
2 |
0.595
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.563
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.562
|
|
|
|
regulation of natural killer cell activation
|
GO:0032814 |
22 |
0.521
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.519
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.518
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.518
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.477
|
|
|
|
response to molecule of fungal origin
|
GO:0002238 |
4 |
0.477
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.468
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
57 |
0.450
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.441
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.440
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.437
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.420
|
|
|
|
cell surface pattern recognition receptor signaling pathway
|
GO:0002752 |
2 |
0.411
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.410
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.393
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.391
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.367
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.366
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.365
|
|
|
|
granulocyte migration
|
GO:0097530 |
43 |
0.359
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.342
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.342
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.337
|
|
|
|
detection of fungus
|
GO:0016046 |
2 |
0.319
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.318
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.306
|
|
|
|
positive regulation of phagocytosis
|
GO:0050766 |
26 |
0.292
|
|
|
|
hematopoietic stem cell migration
|
GO:0035701 |
1 |
0.288
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.284
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.284
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.279
|
|
|
|
positive regulation of t cell receptor signaling pathway
|
GO:0050862 |
4 |
0.271
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.270
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
64 |
0.267
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
61 |
0.266
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.265
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.265
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
51 |
0.264
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.262
|
|
|
|
cellular response to molecule of fungal origin
|
GO:0071226 |
2 |
0.258
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.256
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.256
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.256
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.255
|
|
|
|
positive regulation of regulatory t cell differentiation
|
GO:0045591 |
4 |
0.251
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.248
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.231
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.222
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.218
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.218
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.216
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.215
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.212
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.211
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.209
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.208
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.208
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.203
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
49 |
0.203
|
|
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
52 |
0.200
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.197
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.197
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.190
|
|
|
|
innate immune response activating cell surface receptor signaling pathway
|
GO:0002220 |
4 |
0.187
|
|
|
|
positive regulation of leukocyte mediated cytotoxicity
|
GO:0001912 |
31 |
0.187
|
|
|
|
granulocyte chemotaxis
|
GO:0071621 |
39 |
0.185
|
|
|
|
negative regulation of eosinophil degranulation
|
GO:0043310 |
1 |
0.184
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.181
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.179
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.178
|
|
|
|
interleukin 2 production
|
GO:0032623 |
33 |
0.176
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.171
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.167
|
|
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.166
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
50 |
0.162
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.162
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.160
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
50 |
0.159
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.157
|
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
50 |
0.156
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.156
|
|
|
|
positive regulation of tumor necrosis factor production
|
GO:0032760 |
30 |
0.153
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
65 |
0.150
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.150
|
|
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.149
|
|
|
|
positive regulation of hematopoietic stem cell migration
|
GO:2000473 |
1 |
0.149
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.147
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.147
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.146
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.142
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.137
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.135
|
|
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.135
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.133
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.132
|
|
|
|
positive regulation of alpha beta t cell activation
|
GO:0046635 |
39 |
0.132
|
|
|
|
neutrophil chemotaxis
|
GO:0030593 |
36 |
0.131
|
|
|
|
positive regulation of neutrophil chemotaxis
|
GO:0090023 |
12 |
0.130
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.129
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.127
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.125
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.124
|
|
|
|
positive regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903557 |
31 |
0.124
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.122
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.122
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.121
|
Mouse |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.121
|
|
|
|
regulation of cell killing
|
GO:0031341 |
40 |
0.120
|
|
|
|
regulation of phagocytosis
|
GO:0050764 |
33 |
0.119
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.119
|
|
|
|
positive regulation of t cell costimulation
|
GO:2000525 |
2 |
0.116
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.115
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
29 |
0.115
|
|
|
|
regulation of natural killer cell mediated immunity
|
GO:0002715 |
19 |
0.113
|
|
|
|
regulation of interleukin 2 production
|
GO:0032663 |
28 |
0.112
|
|
|
|
positive regulation of immunological synapse formation
|
GO:2000522 |
1 |
0.111
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.111
|
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.111
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.110
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.109
|
|
|
|
calcium mediated signaling
|
GO:0019722 |
46 |
0.105
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
89 |
0.103
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.102
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.101
|
|
|
|
leukocyte homeostasis
|
GO:0001776 |
79 |
0.101
|
|
|
|
natural killer cell activation
|
GO:0030101 |
44 |
0.101
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.099
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.099
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.097
|
|
|
|
monocyte extravasation
|
GO:0035696 |
2 |
0.097
|
|
|
|
positive regulation of alpha beta t cell differentiation
|
GO:0046638 |
28 |
0.096
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.095
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.094
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
11 |
0.093
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.092
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.091
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.091
|
|
|
|
helper t cell chemotaxis
|
GO:0035704 |
1 |
0.088
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.087
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.087
|
|
|
|
eosinophil activation
|
GO:0043307 |
1 |
0.085
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.085
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.085
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.085
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.083
|
|
|
|
t helper 17 cell chemotaxis
|
GO:0035705 |
1 |
0.083
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.082
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.082
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.082
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.082
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.081
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.080
|
|
|
|
mature dendritic cell differentiation
|
GO:0097029 |
3 |
0.080
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.080
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.079
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
81 |
0.079
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.079
|
|
|
|
antigen processing and presentation of peptide antigen via mhc class i
|
GO:0002474 |
9 |
0.079
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.079
|
|
|
|
interleukin 12 secretion
|
GO:0072610 |
3 |
0.078
|
|
|
|
positive regulation of monocyte chemotaxis
|
GO:0090026 |
2 |
0.078
|
|
|
|
positive regulation of response to wounding
|
GO:1903036 |
66 |
0.078
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
53 |
0.078
|
|
|
|
regulation of wound healing
|
GO:0061041 |
40 |
0.077
|
|
|
|
calcium ion transport into cytosol
|
GO:0060402 |
48 |
0.077
|
|
|
|
muscle contraction
|
GO:0006936 |
101 |
0.075
|
|
|
|
positive regulation of lymphocyte mediated immunity
|
GO:0002708 |
62 |
0.074
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.074
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.073
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
65 |
0.073
|
|
|
|
thymic t cell selection
|
GO:0045061 |
22 |
0.073
|
|
|
|
regulation of alpha beta t cell differentiation
|
GO:0046637 |
35 |
0.073
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.072
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.072
|
|
|
|
regulation of cd4 positive alpha beta t cell activation
|
GO:2000514 |
24 |
0.072
|
|
|
|
regulation of t cell costimulation
|
GO:2000523 |
2 |
0.072
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.071
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.071
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.071
|
|
|
|
positive regulation of endocytosis
|
GO:0045807 |
42 |
0.070
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.070
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.070
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.069
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.069
|
|
|
|
inflammatory response to antigenic stimulus
|
GO:0002437 |
30 |
0.069
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.069
|
|
|
|
regulation of immunoglobulin mediated immune response
|
GO:0002889 |
37 |
0.068
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.068
|
|
|
|
negative regulation of macrophage apoptotic process
|
GO:2000110 |
3 |
0.068
|
|
|
|
t helper 1 type immune response
|
GO:0042088 |
25 |
0.067
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.067
|
|
|
|
antigen processing and presentation
|
GO:0019882 |
47 |
0.067
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.067
|
|
|
|
positive regulation of monocyte extravasation
|
GO:2000439 |
1 |
0.066
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.066
|
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
64 |
0.065
|
|
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
41 |
0.064
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.064
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.064
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.064
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.064
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.063
|
|
|
|
regulation of b cell mediated immunity
|
GO:0002712 |
37 |
0.063
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.061
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.061
|
|
|
|
positive regulation of inflammatory response
|
GO:0050729 |
47 |
0.061
|
|
|
|
regulation of t helper 1 type immune response
|
GO:0002825 |
17 |
0.060
|
|
|
|
positive regulation of type iii hypersensitivity
|
GO:0001805 |
3 |
0.060
|
|
|
|
fc epsilon receptor signaling pathway
|
GO:0038095 |
3 |
0.059
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
85 |
0.059
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.059
|
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.059
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.058
|
|
|
|
cd4 positive cd25 positive alpha beta regulatory t cell differentiation
|
GO:0002361 |
4 |
0.057
|
|
|
|
regulation of eosinophil degranulation
|
GO:0043309 |
1 |
0.057
|
|
|
|
positive regulation of chemotaxis
|
GO:0050921 |
38 |
0.057
|
|
|
|
negative thymic t cell selection
|
GO:0045060 |
12 |
0.057
|
|
|
|
regulation of platelet activation
|
GO:0010543 |
17 |
0.057
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.056
|
|
|
|
regulation of type iii hypersensitivity
|
GO:0001803 |
3 |
0.056
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.056
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.055
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.055
|
|
|
|
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation
|
GO:2000526 |
1 |
0.055
|
|
|
|
granulocyte activation
|
GO:0036230 |
10 |
0.055
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.054
|
|
|
|
serotonin secretion involved in inflammatory response
|
GO:0002442 |
4 |
0.054
|
|
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
61 |
0.054
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.054
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.054
|
|
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
70 |
0.053
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.053
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.053
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
65 |
0.053
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.053
|
|
|
|
acute inflammatory response
|
GO:0002526 |
41 |
0.052
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.052
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.052
|
|
|
|
regulation of monocyte chemotaxis
|
GO:0090025 |
3 |
0.052
|
|
|
|
b cell mediated immunity
|
GO:0019724 |
71 |
0.052
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.051
|
|
|
|
regulation of t cell receptor signaling pathway
|
GO:0050856 |
21 |
0.051
|
|
|
|
alpha beta t cell activation involved in immune response
|
GO:0002287 |
31 |
0.051
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.051
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.051
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.051
|
|
|
|
positive regulation of cd8 positive alpha beta t cell extravasation
|
GO:2000451 |
2 |
0.050
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.050
|
|
|
|
nitric oxide metabolic process
|
GO:0046209 |
25 |
0.050
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.050
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.050
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
74 |
0.050
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.049
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.049
|
|
|
|
positive regulation of cell killing
|
GO:0031343 |
33 |
0.048
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.048
|
|
|
|
detection of other organism
|
GO:0098543 |
8 |
0.048
|
|
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.048
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.048
|
|
|
|
immunoglobulin production
|
GO:0002377 |
73 |
0.048
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.047
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.047
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.046
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.046
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.046
|
|
|
|
fc receptor mediated stimulatory signaling pathway
|
GO:0002431 |
4 |
0.046
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.046
|
|
|
|
nitric oxide biosynthetic process
|
GO:0006809 |
25 |
0.046
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.045
|
|
|
|
lipopolysaccharide mediated signaling pathway
|
GO:0031663 |
25 |
0.045
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.045
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.045
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.045
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.045
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
71 |
0.045
|
|
|
|
placenta development
|
GO:0001890 |
140 |
0.045
|
Mouse |
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.045
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
65 |
0.045
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.045
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.044
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
80 |
0.044
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.044
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.044
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.044
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
88 |
0.044
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.044
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.044
|
|
|
|
positive regulation of cytokine production involved in immune response
|
GO:0002720 |
19 |
0.044
|
|
|
|
regulation of blood coagulation
|
GO:0030193 |
28 |
0.043
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.043
|
|
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
41 |
0.043
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.043
|
|
|
|
regulation of regulated secretory pathway
|
GO:1903305 |
20 |
0.043
|
|
|
|
t cell differentiation involved in immune response
|
GO:0002292 |
30 |
0.043
|
|
|
|
myeloid cell activation involved in immune response
|
GO:0002275 |
34 |
0.042
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.042
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.041
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.041
|
|
|
|
platelet activation
|
GO:0030168 |
40 |
0.041
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
61 |
0.041
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.040
|
|
|
|
b cell activation involved in immune response
|
GO:0002312 |
50 |
0.040
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
62 |
0.040
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.040
|
|
|
|
positive regulation of alpha beta t cell proliferation
|
GO:0046641 |
12 |
0.040
|
|
|
|
regulation of alpha beta t cell proliferation
|
GO:0046640 |
18 |
0.040
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.040
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.040
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.040
|
|
|
|
cellular response to prostaglandin d stimulus
|
GO:0071799 |
1 |
0.040
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.040
|
|
|
|
eosinophil degranulation
|
GO:0043308 |
1 |
0.040
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.040
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.039
|
|
|
|
natural killer cell proliferation
|
GO:0001787 |
3 |
0.039
|
|
|
|
granulocyte macrophage colony stimulating factor production
|
GO:0032604 |
3 |
0.039
|
|
|
|
immunoglobulin production involved in immunoglobulin mediated immune response
|
GO:0002381 |
43 |
0.039
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.039
|
|
|
|
cytokine production involved in immune response
|
GO:0002367 |
34 |
0.039
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.039
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.039
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.039
|
|
|
|
regulation of immunological synapse formation
|
GO:2000520 |
2 |
0.038
|
|
|
|
regulation of coagulation
|
GO:0050818 |
31 |
0.038
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.038
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
61 |
0.038
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.037
|
|
|
|
regulation of smooth muscle contraction
|
GO:0006940 |
22 |
0.037
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.037
|
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.037
|
|
|
|
regulation of t cell extravasation
|
GO:2000407 |
3 |
0.037
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.037
|
|
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.037
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.037
|
|
|
|
alpha beta t cell proliferation
|
GO:0046633 |
21 |
0.037
|
|
|
|
positive regulation of b cell activation
|
GO:0050871 |
49 |
0.037
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.037
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.036
|
|
|
|
regulation of interleukin 1 production
|
GO:0032652 |
26 |
0.036
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.036
|
|
|
|
positive regulation of neutrophil migration
|
GO:1902624 |
12 |
0.036
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.036
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.036
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.036
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
40 |
0.036
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.036
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.035
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.035
|
|
|
|
serotonin production involved in inflammatory response
|
GO:0002351 |
4 |
0.035
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.035
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.035
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.035
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.035
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.035
|
|
|
|
cell killing
|
GO:0001906 |
67 |
0.035
|
|
|
|
positive regulation of calcium mediated signaling
|
GO:0050850 |
15 |
0.035
|
|
|
|
interleukin 6 production
|
GO:0032635 |
58 |
0.035
|
|
|
|
positive regulation of t cell extravasation
|
GO:2000409 |
2 |
0.035
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.034
|
|
|
|
positive regulation of interleukin 10 production
|
GO:0032733 |
12 |
0.034
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.034
|
|
|
|
negative regulation of synapse assembly
|
GO:0051964 |
3 |
0.034
|
|
|
|
positive regulation of cd4 positive alpha beta t cell differentiation
|
GO:0043372 |
14 |
0.034
|
|
|
|
mast cell activation involved in immune response
|
GO:0002279 |
20 |
0.034
|
|
|
|
antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii
|
GO:0002504 |
17 |
0.034
|
|
|
|
regulation of immune complex clearance by monocytes and macrophages
|
GO:0090264 |
2 |
0.034
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.034
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.034
|
|
|
|
serotonin secretion by platelet
|
GO:0002554 |
3 |
0.034
|
|
|
|
regulation of calcium mediated signaling
|
GO:0050848 |
19 |
0.034
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.033
|
|
|
|
regulation of cd4 positive alpha beta t cell differentiation
|
GO:0043370 |
21 |
0.033
|
|
|
|
hypersensitivity
|
GO:0002524 |
10 |
0.033
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
69 |
0.033
|
|
|
|
positive regulation of cd4 positive alpha beta t cell activation
|
GO:2000516 |
16 |
0.033
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
93 |
0.033
|
|
|
|
antigen processing and presentation of peptide antigen
|
GO:0048002 |
29 |
0.032
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.032
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.032
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.032
|
|
|
|
positive regulation of antigen receptor mediated signaling pathway
|
GO:0050857 |
9 |
0.032
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.032
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.031
|
|
|
|
positive regulation of granulocyte chemotaxis
|
GO:0071624 |
12 |
0.031
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.031
|
|
|
|
eosinophil activation involved in immune response
|
GO:0002278 |
1 |
0.031
|
|
|
|
response to interleukin 4
|
GO:0070670 |
23 |
0.031
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.031
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
88 |
0.031
|
|
|
|
response to interferon gamma
|
GO:0034341 |
34 |
0.031
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.031
|
|
|
|
immune complex clearance
|
GO:0002434 |
2 |
0.031
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.031
|
|
|
|
regulation of homotypic cell cell adhesion
|
GO:0034110 |
13 |
0.031
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.031
|
|
|
|
cd8 positive alpha beta t cell extravasation
|
GO:0035697 |
3 |
0.031
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
65 |
0.031
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.030
|
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
52 |
0.030
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.030
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.030
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.030
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.030
|
Mouse |
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.030
|
|
|
|
positive regulation of angiogenesis
|
GO:0045766 |
46 |
0.030
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.030
|
|
|
|
neutrophil activation
|
GO:0042119 |
9 |
0.030
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.030
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.030
|
|
|
|
natural killer cell mediated immunity
|
GO:0002228 |
29 |
0.030
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.030
|
|
|
|
leukocyte mediated cytotoxicity
|
GO:0001909 |
62 |
0.029
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.029
|
|
|
|
regulation of b cell differentiation
|
GO:0045577 |
23 |
0.029
|
|
|
|
positive regulation of lymphocyte differentiation
|
GO:0045621 |
61 |
0.029
|
|
|
|
somatic diversification of immunoglobulins involved in immune response
|
GO:0002208 |
36 |
0.029
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.029
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.029
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.029
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.029
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.029
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.029
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.029
|
|
|
|
t cell activation involved in immune response
|
GO:0002286 |
43 |
0.029
|
|
|
|
eosinophil migration
|
GO:0072677 |
3 |
0.028
|
|
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
39 |
0.028
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.028
|
|
|
|
detection of stimulus
|
GO:0051606 |
84 |
0.028
|
|
|
|
positive regulation of thymocyte migration
|
GO:2000412 |
2 |
0.028
|
|
|
|
regulation of monocyte extravasation
|
GO:2000437 |
2 |
0.028
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
69 |
0.028
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
138 |
0.028
|
|
|
|
membrane invagination
|
GO:0010324 |
17 |
0.027
|
|
|
|
regulation of dendritic cell chemotaxis
|
GO:2000508 |
1 |
0.027
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.027
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.027
|
|
|
|
regulation of neutrophil chemotaxis
|
GO:0090022 |
14 |
0.027
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.027
|
|
|
|
cellular extravasation
|
GO:0045123 |
17 |
0.027
|
|
|
|
bone remodeling
|
GO:0046849 |
53 |
0.027
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.027
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
91 |
0.027
|
|
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.026
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.026
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.026
|
|
|
|
chemokine mediated signaling pathway
|
GO:0070098 |
17 |
0.026
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
88 |
0.026
|
|
|
|
positive regulation of eosinophil migration
|
GO:2000418 |
2 |
0.026
|
|
|
|
positive regulation of interleukin 6 production
|
GO:0032755 |
37 |
0.026
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.026
|
|
|
|
immune complex clearance by monocytes and macrophages
|
GO:0002436 |
2 |
0.026
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.026
|
|
|
|
antimicrobial peptide biosynthetic process
|
GO:0002777 |
2 |
0.026
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.026
|
|
|
|
production of molecular mediator involved in inflammatory response
|
GO:0002532 |
21 |
0.026
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.026
|
|
|
|
positive regulation of gamma delta t cell differentiation
|
GO:0045588 |
6 |
0.026
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.026
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.026
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.026
|
|
|
|
negative regulation of ossification
|
GO:0030279 |
49 |
0.026
|
|
|
|
interleukin 1 beta production
|
GO:0032611 |
30 |
0.025
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
116 |
0.025
|
|
|
|
transepithelial chloride transport
|
GO:0030321 |
4 |
0.025
|
|
|
|
eosinophil mediated immunity
|
GO:0002447 |
1 |
0.025
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.025
|
|
|
|
positive regulation of myotube differentiation
|
GO:0010831 |
24 |
0.025
|
|
|
|
microglial cell activation
|
GO:0001774 |
3 |
0.025
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.025
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.025
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.025
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.025
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.025
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.024
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.024
|
|
|
|
positive regulation of myeloid leukocyte cytokine production involved in immune response
|
GO:0061081 |
9 |
0.024
|
|
|
|
regulation of granulocyte chemotaxis
|
GO:0071622 |
17 |
0.024
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.024
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.024
|
|
|
|
negative t cell selection
|
GO:0043383 |
13 |
0.024
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
41 |
0.024
|
|
