|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.963
|
|
|
|
ovulation cycle
|
GO:0042698 |
59 |
0.933
|
Human |
|
|
ovarian follicle development
|
GO:0001541 |
40 |
0.913
|
Human |
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.909
|
|
|
|
female sex differentiation
|
GO:0046660 |
84 |
0.904
|
Human |
|
|
cytokine production
|
GO:0001816 |
319 |
0.883
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.873
|
|
|
|
development of primary female sexual characteristics
|
GO:0046545 |
73 |
0.872
|
Human |
|
|
rhythmic process
|
GO:0048511 |
174 |
0.863
|
Human |
|
|
follicle stimulating hormone secretion
|
GO:0046884 |
1 |
0.860
|
Human |
|
|
female gonad development
|
GO:0008585 |
71 |
0.823
|
Human |
|
|
regulation of system process
|
GO:0044057 |
200 |
0.785
|
Human |
|
|
response to growth factor
|
GO:0070848 |
198 |
0.784
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.779
|
Human |
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.771
|
Mouse Rat |
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.768
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.765
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.752
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.752
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.750
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.744
|
Human Mouse |
|
|
odontogenesis
|
GO:0042476 |
78 |
0.688
|
Human |
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.685
|
Mouse |
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.655
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.634
|
|
|
|
odontogenesis of dentin containing tooth
|
GO:0042475 |
66 |
0.633
|
|
|
|
skeletal system morphogenesis
|
GO:0048705 |
203 |
0.623
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.610
|
Human Mouse |
|
|
activation of immune response
|
GO:0002253 |
138 |
0.602
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.595
|
|
|
|
positive regulation of reproductive process
|
GO:2000243 |
19 |
0.586
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.583
|
Rat |
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.581
|
Mouse |
|
|
bmp signaling pathway
|
GO:0030509 |
93 |
0.567
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.566
|
Human Mouse |
|
|
skeletal system development
|
GO:0001501 |
356 |
0.556
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.549
|
|
|
|
regulation of ovulation
|
GO:0060278 |
3 |
0.540
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.536
|
Mouse |
|
|
chemotaxis
|
GO:0006935 |
247 |
0.536
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.536
|
|
|
|
ear development
|
GO:0043583 |
200 |
0.532
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.531
|
|
|
|
extracellular structure organization
|
GO:0043062 |
148 |
0.521
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.520
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.520
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.517
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.516
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.514
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.500
|
Mouse |
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.487
|
Human |
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.485
|
Human |
|
|
gonad development
|
GO:0008406 |
141 |
0.482
|
Human |
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.481
|
|
|
|
activin receptor signaling pathway
|
GO:0032924 |
18 |
0.478
|
Human |
|
|
response to cholesterol
|
GO:0070723 |
4 |
0.476
|
Rat |
|
|
gland development
|
GO:0048732 |
330 |
0.472
|
|
|
|
cartilage development
|
GO:0051216 |
140 |
0.466
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.462
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.458
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.457
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.449
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.448
|
|
|
|
renal system development
|
GO:0072001 |
225 |
0.445
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.440
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.438
|
|
|
|
female gamete generation
|
GO:0007292 |
74 |
0.436
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.433
|
|
|
|
negative regulation of activin receptor signaling pathway
|
GO:0032926 |
6 |
0.432
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.426
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.424
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.420
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.416
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.416
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.415
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.409
|
Human |
|
|
bone development
|
GO:0060348 |
120 |
0.404
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.400
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.399
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.394
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.387
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.386
|
Human |
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.380
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.380
|
Human |
|
|
mesenchymal cell development
|
GO:0014031 |
93 |
0.377
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.373
|
Human |
|
|
cellular response to gonadotropin stimulus
|
GO:0071371 |
4 |
0.369
|
Rat |
|
|
negative regulation of secretion
|
GO:0051048 |
61 |
0.361
|
Mouse |
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.356
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.353
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.352
|
Mouse |
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.352
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.352
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
61 |
0.349
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.349
|
|
|
|
mesenchyme development
|
GO:0060485 |
152 |
0.344
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.344
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.333
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
107 |
0.331
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.330
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.326
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.325
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.324
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
144 |
0.323
|
|
|
|
hair follicle development
|
GO:0001942 |
85 |
0.321
|
Human |
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.315
|
|
|
|
kidney epithelium development
|
GO:0072073 |
121 |
0.314
|
|
|
|
organ growth
|
GO:0035265 |
117 |
0.312
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.309
|
|
|
|
negative regulation of bmp signaling pathway
|
GO:0030514 |
35 |
0.306
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.306
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.305
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.304
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.304
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.300
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.300
|
|
|
|
regulation of reproductive process
|
GO:2000241 |
66 |
0.299
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.296
|
|
|
|
male sex differentiation
|
GO:0046661 |
109 |
0.294
|
Human |
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.293
|
|
|
|
wnt signaling pathway involved in kidney development
|
GO:0061289 |
2 |
0.292
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.292
|
|
|
|
mesendoderm development
|
GO:0048382 |
3 |
0.289
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.279
|
Mouse |
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.278
|
|
|
|
kidney development
|
GO:0001822 |
213 |
0.276
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.275
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.274
|
|
|
|
nephron development
|
GO:0072006 |
109 |
0.272
|
|
|
|
endochondral bone morphogenesis
|
GO:0060350 |
50 |
0.267
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.266
|
Mouse |
|
|
defense response to gram negative bacterium
|
GO:0050829 |
28 |
0.261
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.260
|
|
|
|
peptide secretion
|
GO:0002790 |
114 |
0.260
|
Mouse |
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.260
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.253
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.252
|
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
64 |
0.252
|
Human |
|
|
response to drug
|
GO:0042493 |
75 |
0.250
|
Human |
|
|
regulation of activin receptor signaling pathway
|
GO:0032925 |
10 |
0.246
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.246
|
|
|
|
oocyte differentiation
|
GO:0009994 |
35 |
0.246
|
Mouse |
|
|
cellular response to follicle stimulating hormone stimulus
|
GO:0071372 |
1 |
0.244
|
Rat |
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.242
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
101 |
0.240
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.239
|
Human |
|
|
ear morphogenesis
|
GO:0042471 |
118 |
0.237
|
|
|
|
negative regulation of secretion by cell
|
GO:1903531 |
54 |
0.236
|
Mouse |
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.235
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.228
|
Human Mouse |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.228
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.228
|
Human |
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.223
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.223
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
77 |
0.223
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.222
|
Human Mouse |
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.222
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.222
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.222
|
|
|
|
peptide hormone secretion
|
GO:0030072 |
109 |
0.219
|
Mouse |
|
|
chromatin organization
|
GO:0006325 |
206 |
0.219
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.218
|
Mouse |
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.215
|
Human |
|
|
regulation of chromosome organization
|
GO:0033044 |
83 |
0.215
|
|
|
|
endoderm development
|
GO:0007492 |
45 |
0.211
|
Human |
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
68 |
0.211
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.210
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.210
|
|
|
|
mesoderm development
|
GO:0007498 |
100 |
0.209
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.209
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
87 |
0.208
|
Rat |
|
|
cellular response to leptin stimulus
|
GO:0044320 |
6 |
0.207
|
Mouse |
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.206
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.204
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.204
|
|
|
|
spermatid development
|
GO:0007286 |
108 |
0.203
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.201
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.201
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.200
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.199
|
|
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
60 |
0.198
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.198
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.197
|
Human Mouse |
|
|
biomineral tissue development
|
GO:0031214 |
64 |
0.194
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.194
|
|
|
|
spermatid differentiation
|
GO:0048515 |
115 |
0.194
|
|
|
|
regulation of blood pressure
|
GO:0008217 |
93 |
0.191
|
|
|
|
embryonic viscerocranium morphogenesis
|
GO:0048703 |
8 |
0.191
|
|
|
|
limb morphogenesis
|
GO:0035108 |
149 |
0.191
|
|
|
|
oogenesis
|
GO:0048477 |
56 |
0.191
|
Mouse |
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.189
|
|
|
|
response to steroid hormone
|
GO:0048545 |
56 |
0.189
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.189
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.188
|
|
|
|
positive regulation of angiogenesis
|
GO:0045766 |
46 |
0.185
|
|
|
|
lung alveolus development
|
GO:0048286 |
45 |
0.183
|
|
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.182
|
Mouse |
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.181
|
|
|
|
mesoderm morphogenesis
|
GO:0048332 |
64 |
0.180
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.178
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.177
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.177
|
Mouse |
|
|
b cell activation
|
GO:0042113 |
161 |
0.174
|
|
|
|
organic hydroxy compound biosynthetic process
|
GO:1901617 |
77 |
0.174
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.174
|
|
|
|
hair follicle morphogenesis
|
GO:0031069 |
29 |
0.173
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.173
|
Zebrafish |
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.172
|
|
|
|
lung development
|
GO:0030324 |
164 |
0.172
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.172
|
|
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
47 |
0.169
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.166
|
|
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.165
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.164
|
|
|
|
positive regulation of lymphocyte differentiation
|
GO:0045621 |
61 |
0.162
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.160
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.160
|
|
|
|
oocyte development
|
GO:0048599 |
33 |
0.160
|
Mouse |
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.160
|
|
|
|
cellular response to alcohol
|
GO:0097306 |
23 |
0.159
|
Rat |
|
|
defense response to virus
|
GO:0051607 |
68 |
0.158
|
|
|
|
pancreas development
|
GO:0031016 |
57 |
0.157
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.157
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.155
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.153
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
130 |
0.152
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.150
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.149
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.149
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.148
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.148
|
|
|
|
regulation of fat cell differentiation
|
GO:0045598 |
81 |
0.147
|
|
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.147
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.146
|
|
|
|
mesonephric epithelium development
|
GO:0072163 |
94 |
0.146
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.146
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
97 |
0.146
|
|
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.144
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
44 |
0.143
|
Human |
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.143
|
|
|
|
regulation of cartilage development
|
GO:0061035 |
44 |
0.142
|
|
|
|
male gonad development
|
GO:0008584 |
88 |
0.140
|
Human |
|
|
placenta development
|
GO:0001890 |
140 |
0.139
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.139
|
|
|
|
development of primary male sexual characteristics
|
GO:0046546 |
88 |
0.139
|
Human |
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.137
|
|
|
|
embryonic skeletal system development
|
GO:0048706 |
120 |
0.137
|
|
|
|
antimicrobial peptide biosynthetic process
|
GO:0002777 |
2 |
0.135
|
|
|
|
protein acylation
|
GO:0043543 |
64 |
0.133
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.133
|
|
|
|
toll like receptor signaling pathway
|
GO:0002224 |
38 |
0.132
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.132
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.132
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.132
|
|
|
|
myeloid dendritic cell activation
|
GO:0001773 |
25 |
0.132
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.130
|
|
|
|
molting cycle
|
GO:0042303 |
90 |
0.129
|
Human |
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
43 |
0.128
|
Human |
|
|
negative regulation of cartilage development
|
GO:0061037 |
17 |
0.127
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.127
|
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.127
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.126
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.126
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.126
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.125
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.125
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.124
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.124
|
|
|
|
determination of dorsal identity
|
GO:0048263 |
5 |
0.124
|
|
|
|
regulation of tube size
|
GO:0035150 |
57 |
0.123
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.123
|
Human |
|
|
embryonic appendage morphogenesis
|
GO:0035113 |
126 |
0.123
|
|
|
|
regulation of hair cycle
|
GO:0042634 |
11 |
0.123
|
|
|
|
regulation of ossification
|
GO:0030278 |
112 |
0.122
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.122
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.121
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.121
|
|
|
|
regulation of toll like receptor signaling pathway
|
GO:0034121 |
20 |
0.121
|
|
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.120
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.119
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.119
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.119
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.118
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.118
|
|
|
|
mesonephros development
|
GO:0001823 |
97 |
0.116
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.116
|
Human Mouse |
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.115
|
|
|
|
regulation of peptidyl lysine acetylation
|
GO:2000756 |
22 |
0.115
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.114
|
|
|
|
muscle hypertrophy
|
GO:0014896 |
24 |
0.113
|
|
|
|
otic placode formation
|
GO:0043049 |
1 |
0.110
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.109
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.109
|
|
|
|
response to testosterone
|
GO:0033574 |
3 |
0.109
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.108
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.108
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.108
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.108
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.105
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.105
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.104
|
|
|
|
vascular process in circulatory system
|
GO:0003018 |
62 |
0.103
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.102
|
|
|
|
regulation of hair follicle development
|
GO:0051797 |
9 |
0.101
|
|
|
|
positive regulation of multi organism process
|
GO:0043902 |
26 |
0.100
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.100
|
Human |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.099
|
|
|
|
ureteric bud development
|
GO:0001657 |
94 |
0.098
|
|
|
|
keratinocyte proliferation
|
GO:0043616 |
21 |
0.097
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.097
|
Human Mouse |
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.097
|
|
|
|
nephron morphogenesis
|
GO:0072028 |
69 |
0.097
|
|
|
|
negative regulation of t cell proliferation
|
GO:0042130 |
38 |
0.095
|
|
|
|
endothelium development
|
GO:0003158 |
45 |
0.095
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.094
|
|
|
|
positive regulation of hair follicle development
|
GO:0051798 |
6 |
0.094
|
|
|
|
regulation of epithelial to mesenchymal transition
|
GO:0010717 |
22 |
0.094
|
|
|
|
endocrine hormone secretion
|
GO:0060986 |
15 |
0.094
|
Human |
|
|
negative regulation of peptide secretion
|
GO:0002792 |
16 |
0.093
|
Mouse |
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.092
|
|
|
|
endochondral bone growth
|
GO:0003416 |
19 |
0.092
|
|
|
|
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090100 |
43 |
0.092
|
Human |
|
|
regulation of binding
|
GO:0051098 |
111 |
0.091
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.091
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.090
|
Human |
|
|
cell fate determination
|
GO:0001709 |
32 |
0.089
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.089
|
|
|
|
acute inflammatory response
|
GO:0002526 |
41 |
0.089
|
|
|
|
regulation of chromatin organization
|
GO:1902275 |
57 |
0.088
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.088
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.088
|
|
|
|
insulin secretion
|
GO:0030073 |
89 |
0.087
|
Mouse |
|
|
epidermis morphogenesis
|
GO:0048730 |
33 |
0.087
|
|
|
|
regulation of feeding behavior
|
GO:0060259 |
3 |
0.087
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.085
|
|
|
|
regulation of chromatin modification
|
GO:1903308 |
57 |
0.085
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.085
|
Human Mouse |
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.084
|
|
|
|
negative regulation of bone remodeling
|
GO:0046851 |
6 |
0.084
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.084
|
|
|
|
response to insulin
|
GO:0032868 |
100 |
0.084
|
Mouse |
|
|
cartilage condensation
|
GO:0001502 |
18 |
0.084
|
|
|
|
spermatogenesis exchange of chromosomal proteins
|
GO:0035093 |
4 |
0.084
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.082
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.081
|
Human |
|
|
skin morphogenesis
|
GO:0043589 |
38 |
0.081
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.080
|
|
|
|
regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001239 |
26 |
0.080
|
Human |
|
|
muscle adaptation
|
GO:0043500 |
39 |
0.080
|
|
|
|
neural crest cell development
|
GO:0014032 |
48 |
0.080
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.079
|
|
|
|
negative regulation of fat cell differentiation
|
GO:0045599 |
36 |
0.079
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.079
|
|
|
|
chondrocyte differentiation
|
GO:0002062 |
72 |
0.078
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.078
|
|
|
|
gastrulation
|
GO:0007369 |
116 |
0.078
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.078
|
|
|
|
response to sterol
|
GO:0036314 |
4 |
0.078
|
Rat |
|
|
canonical wnt signaling pathway involved in metanephric kidney development
|
GO:0061290 |
2 |
0.077
|
|
|
|
connective tissue development
|
GO:0061448 |
179 |
0.077
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.077
|
|
|
|
embryonic skeletal system morphogenesis
|
GO:0048704 |
91 |
0.077
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.076
|
|
|
|
response to purine containing compound
|
GO:0014074 |
28 |
0.076
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.076
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.076
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.075
|
|
|
|
response to estrogen
|
GO:0043627 |
24 |
0.075
|
|
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.075
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.075
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.075
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
57 |
0.075
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.075
|
|
|
|
central nervous system neuron differentiation
|
GO:0021953 |
162 |
0.074
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
61 |
0.074
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
88 |
0.074
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.074
|
|
|
|
activation of transmembrane receptor protein tyrosine kinase activity
|
GO:0007171 |
3 |
0.074
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.074
|
|
|
|
sertoli cell differentiation
|
GO:0060008 |
18 |
0.073
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.073
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
59 |
0.073
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.073
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.072
|
|
|
|
regulation of histone acetylation
|
GO:0035065 |
19 |
0.072
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
89 |
0.072
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.072
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.072
|
|
|
|
collagen fibril organization
|
GO:0030199 |
32 |
0.072
|
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.072
|
Human |
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.072
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.071
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.071
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.071
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.070
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.070
|
|
|
|
hair cycle
|
GO:0042633 |
90 |
0.070
|
Human |
|
|
organelle assembly
|
GO:0070925 |
177 |
0.069
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.069
|
|
|
|
positive regulation of hair cycle
|
GO:0042635 |
7 |
0.068
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.068
|
Human |
|
|
protein targeting
|
GO:0006605 |
143 |
0.068
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.067
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.067
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.067
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.067
|
|
|
|
regulation of female gonad development
|
GO:2000194 |
7 |
0.067
|
|
|
|
bone morphogenesis
|
GO:0060349 |
78 |
0.066
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.066
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.066
|
Human |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.066
|
|
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
41 |
0.066
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.066
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
78 |
0.065
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.064
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
71 |
0.064
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.064
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.064
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.064
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
|
GO:1902043 |
13 |
0.064
|
|
|
|
cellular response to starvation
|
GO:0009267 |
57 |
0.063
|
Mouse |
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
34 |
0.063
|
Human |
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.063
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.063
|
|
|
|
antimicrobial peptide production
|
GO:0002775 |
2 |
0.063
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.063
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.062
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.062
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
74 |
0.062
|
|
|
|
seminiferous tubule development
|
GO:0072520 |
14 |
0.062
|
|
|
|
tissue migration
|
GO:0090130 |
68 |
0.062
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.062
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.061
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
92 |
0.060
|
|
|
|
endocrine process
|
GO:0050886 |
39 |
0.060
|
Human |
|
|
regulation of ras gtpase activity
|
GO:0032318 |
88 |
0.060
|
|
|
|
myeloid dendritic cell differentiation
|
GO:0043011 |
16 |
0.060
|
|
|
|
tolerance induction
|
GO:0002507 |
14 |
0.060
|
|
|
|
spinal cord development
|
GO:0021510 |
81 |
0.060
|
|
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.059
|
|
|
|
natural killer cell activation
|
GO:0030101 |
44 |
0.059
|
|
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.059
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.059
|
|
|
|
phenol containing compound metabolic process
|
GO:0018958 |
60 |
0.058
|
|
|
|
thymus development
|
GO:0048538 |
41 |
0.058
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
53 |
0.058
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.058
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.058
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.058
|
|
|
|
interleukin 6 production
|
GO:0032635 |
58 |
0.057
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.057
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.057
|
|
|
|
diencephalon development
|
GO:0021536 |
63 |
0.057
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.057
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.057
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
47 |
0.056
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.056
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.056
|
Human |
|
|
positive regulation of stem cell proliferation
|
GO:2000648 |
59 |
0.056
|
|
|
|
cellular water homeostasis
|
GO:0009992 |
2 |
0.056
|
|
|
|
regulation of steroid hormone biosynthetic process
|
GO:0090030 |
4 |
0.056
|
|
|
|
histone modification
|
GO:0016570 |
159 |
0.056
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.055
|
|
|
|
mesonephric tubule development
|
GO:0072164 |
94 |
0.055
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.054
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.054
|
|
|
|
bone resorption
|
GO:0045453 |
38 |
0.054
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
79 |
0.054
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.054
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.054
|
|
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.053
|
|
|
|
nuclear import
|
GO:0051170 |
95 |
0.053
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
132 |
0.052
|
|
|
|
cell cell signaling involved in metanephros development
|
GO:0072204 |
2 |
0.052
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.052
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
108 |
0.052
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
70 |
0.052
|
|
|
|
nephron epithelium development
|
GO:0072009 |
92 |
0.052
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.052
|
|
|
|
phenol containing compound biosynthetic process
|
GO:0046189 |
21 |
0.052
|
|
|
|
chromatin modification
|
GO:0016568 |
187 |
0.052
|
|
|
|
uterus development
|
GO:0060065 |
16 |
0.052
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.052
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.052
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
45 |
0.051
|
|
|
|
limbic system development
|
GO:0021761 |
72 |
0.051
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.051
|
Rat |
|
|
growth plate cartilage development
|
GO:0003417 |
14 |
0.051
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.050
|
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.050
|
|
|
|
neuron migration
|
GO:0001764 |
122 |
0.050
|
|
|
|
nephron epithelium morphogenesis
|
GO:0072088 |
68 |
0.050
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.050
|
|
|
|
trachea formation
|
GO:0060440 |
3 |
0.049
|
|
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.049
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.049
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.049
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
74 |
0.049
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.049
|
|
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
30 |
0.049
|
|
