|
|
regulation of carbohydrate biosynthetic process
|
GO:0043255 |
40 |
1.000
|
|
|
|
regulation of glucan biosynthetic process
|
GO:0010962 |
7 |
1.000
|
|
|
|
regulation of insulin receptor signaling pathway
|
GO:0046626 |
21 |
1.000
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
1.000
|
|
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.999
|
|
|
|
regulation of glycogen metabolic process
|
GO:0070873 |
13 |
0.999
|
|
|
|
glycogen biosynthetic process
|
GO:0005978 |
14 |
0.999
|
|
|
|
regulation of glucose metabolic process
|
GO:0010906 |
60 |
0.999
|
|
|
|
carbohydrate biosynthetic process
|
GO:0016051 |
74 |
0.998
|
|
|
|
insulin receptor signaling pathway
|
GO:0008286 |
49 |
0.997
|
|
|
|
glycogen metabolic process
|
GO:0005977 |
32 |
0.996
|
|
|
|
energy reserve metabolic process
|
GO:0006112 |
39 |
0.996
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
78 |
0.996
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
106 |
0.996
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.995
|
|
|
|
positive regulation of glucose metabolic process
|
GO:0010907 |
21 |
0.993
|
|
|
|
polysaccharide biosynthetic process
|
GO:0000271 |
20 |
0.991
|
|
|
|
regulation of fatty acid metabolic process
|
GO:0019217 |
28 |
0.990
|
|
|
|
negative regulation of cellular response to insulin stimulus
|
GO:1900077 |
16 |
0.989
|
|
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
75 |
0.989
|
|
|
|
positive regulation of cellular carbohydrate metabolic process
|
GO:0010676 |
29 |
0.987
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.984
|
|
|
|
regulation of glycogen biosynthetic process
|
GO:0005979 |
7 |
0.983
|
|
|
|
glucose metabolic process
|
GO:0006006 |
92 |
0.982
|
|
|
|
energy derivation by oxidation of organic compounds
|
GO:0015980 |
77 |
0.981
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
92 |
0.980
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.979
|
|
|
|
glucan metabolic process
|
GO:0044042 |
32 |
0.979
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.977
|
|
|
|
glucan biosynthetic process
|
GO:0009250 |
14 |
0.975
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
191 |
0.975
|
Human |
|
|
hexose metabolic process
|
GO:0019318 |
98 |
0.975
|
|
|
|
regulation of fatty acid oxidation
|
GO:0046320 |
10 |
0.975
|
|
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.975
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.974
|
|
|
|
regulation of steroid biosynthetic process
|
GO:0050810 |
26 |
0.973
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.969
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.964
|
|
|
|
cellular glucan metabolic process
|
GO:0006073 |
32 |
0.963
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
119 |
0.960
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.957
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.955
|
Mouse Rat |
|
|
regulation of gluconeogenesis
|
GO:0006111 |
30 |
0.955
|
|
|
|
regulation of polysaccharide biosynthetic process
|
GO:0032885 |
7 |
0.952
|
|
|
|
positive regulation of insulin receptor signaling pathway
|
GO:0046628 |
4 |
0.950
|
|
|
|
cellular polysaccharide metabolic process
|
GO:0044264 |
38 |
0.948
|
|
|
|
response to insulin
|
GO:0032868 |
100 |
0.946
|
|
|
|
asymmetric stem cell division
|
GO:0098722 |
3 |
0.940
|
Fly |
|
|
positive regulation of fatty acid oxidation
|
GO:0046321 |
4 |
0.937
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.936
|
Mouse Rat |
|
|
glucose import
|
GO:0046323 |
32 |
0.936
|
Human |
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.935
|
Human |
|
|
lactation
|
GO:0007595 |
25 |
0.927
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.925
|
|
|
|
response to oxygen levels
|
GO:0070482 |
62 |
0.922
|
Fly |
|
|
regulation of polysaccharide metabolic process
|
GO:0032881 |
13 |
0.918
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.917
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
74 |
0.917
|
Human Mouse |
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
40 |
0.916
|
|
|
|
regulation of cellular carbohydrate metabolic process
|
GO:0010675 |
75 |
0.914
|
|
|
|
regulation of circadian sleep wake cycle sleep
|
GO:0045187 |
3 |
0.912
|
Fly |
|
|
gluconeogenesis
|
GO:0006094 |
39 |
0.909
|
|
|
|
negative regulation of cellular carbohydrate metabolic process
|
GO:0010677 |
19 |
0.908
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.908
|
Human |
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.906
|
Human Mouse |
|
|
regulation of feeding behavior
|
GO:0060259 |
3 |
0.906
|
Fly |
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.904
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.903
|
|
|
|
regulation of cellular response to insulin stimulus
|
GO:1900076 |
30 |
0.902
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.900
|
Rat Worm |
|
|
regulation of nitrogen cycle metabolic process
|
GO:1903314 |
1 |
0.900
|
|
|
|
negative regulation of hormone secretion
|
GO:0046888 |
20 |
0.896
|
|
|
|
negative regulation of insulin receptor signaling pathway
|
GO:0046627 |
14 |
0.895
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.891
|
Rat Fly |
|
|
negative regulation of feeding behavior
|
GO:2000252 |
1 |
0.889
|
Fly |
|
|
response to decreased oxygen levels
|
GO:0036293 |
59 |
0.888
|
Fly |
|
|
carbohydrate transport
|
GO:0008643 |
62 |
0.888
|
Human |
|
|
response to monosaccharide
|
GO:0034284 |
67 |
0.886
|
Rat |
|
|
mapk cascade
|
GO:0000165 |
281 |
0.883
|
Human Mouse |
|
|
polysaccharide metabolic process
|
GO:0005976 |
39 |
0.883
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.879
|
|
|
|
male germ line stem cell asymmetric division
|
GO:0048133 |
2 |
0.874
|
Fly |
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.873
|
|
|
|
acylglycerol metabolic process
|
GO:0006639 |
55 |
0.871
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.871
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.864
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.859
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
88 |
0.851
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.851
|
Human |
|
|
insulin like growth factor receptor signaling pathway
|
GO:0048009 |
21 |
0.841
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.839
|
|
|
|
response to starvation
|
GO:0042594 |
65 |
0.837
|
Worm |
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.834
|
Mouse |
|
|
positive regulation of glycogen biosynthetic process
|
GO:0045725 |
6 |
0.832
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.829
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.825
|
|
|
|
hexose biosynthetic process
|
GO:0019319 |
39 |
0.821
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.819
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
91 |
0.818
|
|
|
|
regulation of circadian rhythm
|
GO:0042752 |
58 |
0.817
|
Fly |
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.802
|
Fly |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.797
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.792
|
Human Worm Fly |
|
|
hormone secretion
|
GO:0046879 |
128 |
0.786
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.786
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.783
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
121 |
0.780
|
|
|
|
brown fat cell differentiation
|
GO:0050873 |
36 |
0.779
|
|
|
|
regulation of lipid biosynthetic process
|
GO:0046890 |
54 |
0.776
|
|
|
|
neutral lipid metabolic process
|
GO:0006638 |
57 |
0.772
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.772
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.772
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.770
|
Human |
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.768
|
|
|
|
glucose transport
|
GO:0015758 |
56 |
0.764
|
Human |
|
|
positive regulation of carbohydrate metabolic process
|
GO:0045913 |
30 |
0.762
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.752
|
Rat |
|
|
mitochondrion organization
|
GO:0007005 |
134 |
0.744
|
|
|
|
circadian regulation of gene expression
|
GO:0032922 |
48 |
0.743
|
|
|
|
cellular polysaccharide biosynthetic process
|
GO:0033692 |
19 |
0.736
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.733
|
|
|
|
cellular lipid catabolic process
|
GO:0044242 |
52 |
0.725
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.722
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.720
|
|
|
|
positive regulation of vasoconstriction
|
GO:0045907 |
4 |
0.716
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.709
|
Human Mouse |
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
74 |
0.700
|
|
|
|
lipid transport
|
GO:0006869 |
98 |
0.689
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.686
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.674
|
Rat |
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.670
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.670
|
Mouse Rat |
|
|
keratinocyte migration
|
GO:0051546 |
3 |
0.669
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.665
|
Mouse |
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.665
|
Worm Fly |
|
|
negative regulation of secretion
|
GO:0051048 |
61 |
0.664
|
|
|
|
regulation of peptide hormone secretion
|
GO:0090276 |
75 |
0.661
|
|
|
|
regulation of generation of precursor metabolites and energy
|
GO:0043467 |
38 |
0.651
|
|
|
|
regulation of glutamate metabolic process
|
GO:2000211 |
1 |
0.647
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.645
|
|
|
|
positive regulation of apoptotic process involved in mammary gland involution
|
GO:0060058 |
4 |
0.640
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.633
|
|
|
|
anion transport
|
GO:0006820 |
177 |
0.633
|
Mouse |
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.630
|
Human |
|
|
organic hydroxy compound transport
|
GO:0015850 |
93 |
0.623
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.619
|
Rat |
|
|
glycerolipid metabolic process
|
GO:0046486 |
122 |
0.618
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.614
|
Human |
|
|
mammary gland epithelium development
|
GO:0061180 |
65 |
0.612
|
|
|
|
cellular response to alkaline ph
|
GO:0071469 |
1 |
0.612
|
Mouse |
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.610
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.607
|
|
|
|
peptide hormone secretion
|
GO:0030072 |
109 |
0.607
|
|
|
|
regulation of circadian sleep wake cycle
|
GO:0042749 |
3 |
0.602
|
Fly |
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.599
|
Rat Worm |
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.598
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.589
|
|
|
|
negative regulation of carbohydrate metabolic process
|
GO:0045912 |
19 |
0.587
|
|
|
|
alpha amino acid metabolic process
|
GO:1901605 |
59 |
0.587
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.584
|
Fly |
|
|
wound healing
|
GO:0042060 |
157 |
0.582
|
|
|
|
triglyceride metabolic process
|
GO:0006641 |
51 |
0.582
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.579
|
|
|
|
response to bile acid
|
GO:1903412 |
1 |
0.577
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.574
|
|
|
|
glycolytic process
|
GO:0006096 |
20 |
0.573
|
Human |
|
|
steroid metabolic process
|
GO:0008202 |
119 |
0.572
|
|
|
|
regulation of glutamine family amino acid metabolic process
|
GO:0000820 |
1 |
0.571
|
|
|
|
lipid oxidation
|
GO:0034440 |
29 |
0.567
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.558
|
Mouse |
|
|
ammonia assimilation cycle
|
GO:0019676 |
2 |
0.557
|
|
|
|
macromolecule methylation
|
GO:0043414 |
120 |
0.557
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.554
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.553
|
|
|
|
monocarboxylic acid catabolic process
|
GO:0072329 |
27 |
0.551
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.537
|
|
|
|
negative regulation of lipid metabolic process
|
GO:0045833 |
30 |
0.535
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.534
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.532
|
Human |
|
|
inositol lipid mediated signaling
|
GO:0048017 |
41 |
0.526
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.522
|
Mouse |
|
|
cell division
|
GO:0051301 |
120 |
0.519
|
|
|
|
cellular carbohydrate catabolic process
|
GO:0044275 |
15 |
0.517
|
Human |
|
|
cellular response to external stimulus
|
GO:0071496 |
88 |
0.517
|
Worm |
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
41 |
0.516
|
|
|
|
cell proliferation in hindbrain
|
GO:0021534 |
10 |
0.511
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.508
|
|
|
|
lipid modification
|
GO:0030258 |
65 |
0.507
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.505
|
Human |
|
|
regulation of steroid metabolic process
|
GO:0019218 |
39 |
0.501
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.499
|
Rat Fly |
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.488
|
Worm Fly |
|
|
negative regulation of peptide secretion
|
GO:0002792 |
16 |
0.481
|
|
|
|
connective tissue development
|
GO:0061448 |
179 |
0.479
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
64 |
0.475
|
Worm |
|
|
apoptotic process involved in mammary gland involution
|
GO:0060057 |
4 |
0.474
|
|
|
|
negative regulation of secretion by cell
|
GO:1903531 |
54 |
0.472
|
|
|
|
vitamin d biosynthetic process
|
GO:0042368 |
3 |
0.472
|
|
|
|
negative regulation of triglyceride metabolic process
|
GO:0090209 |
4 |
0.472
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.472
|
|
|
|
urea metabolic process
|
GO:0019627 |
3 |
0.470
|
|
|
|
regulation of urea metabolic process
|
GO:0034255 |
1 |
0.463
|
|
|
|
lipid catabolic process
|
GO:0016042 |
69 |
0.463
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.458
|
|
|
|
body fluid secretion
|
GO:0007589 |
53 |
0.457
|
|
|
|
apoptotic mitochondrial changes
|
GO:0008637 |
48 |
0.457
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.456
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.456
|
Fly |
|
|
negative regulation of peptide hormone secretion
|
GO:0090278 |
16 |
0.455
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.453
|
Human |
|
|
regulation of the force of heart contraction by chemical signal
|
GO:0003057 |
5 |
0.452
|
|
|
|
glucose homeostasis
|
GO:0042593 |
128 |
0.448
|
Human Rat |
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.448
|
|
|
|
positive regulation of insulin secretion
|
GO:0032024 |
26 |
0.444
|
|
|
|
regulation of peptide secretion
|
GO:0002791 |
77 |
0.444
|
|
|
|
mammary gland lobule development
|
GO:0061377 |
22 |
0.439
|
|
|
|
release of cytochrome c from mitochondria
|
GO:0001836 |
23 |
0.436
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.435
|
|
|
|
response to alcohol
|
GO:0097305 |
48 |
0.430
|
Rat |
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.426
|
Worm |
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
36 |
0.425
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.412
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.412
|
Worm |
|
|
mammary gland duct morphogenesis
|
GO:0060603 |
38 |
0.410
|
|
|
|
monosaccharide biosynthetic process
|
GO:0046364 |
44 |
0.406
|
|
|
|
cyclic purine nucleotide metabolic process
|
GO:0052652 |
43 |
0.405
|
|
|
|
peptide secretion
|
GO:0002790 |
114 |
0.402
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.392
|
Fly |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.389
|
Human |
|
|
insulin secretion
|
GO:0030073 |
89 |
0.386
|
|
|
|
small molecule catabolic process
|
GO:0044282 |
71 |
0.386
|
|
|
|
negative regulation of gluconeogenesis
|
GO:0045721 |
9 |
0.382
|
|
|
|
regulation of triglyceride metabolic process
|
GO:0090207 |
17 |
0.381
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.380
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.374
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.373
|
|
|
|
cellular glucose homeostasis
|
GO:0001678 |
52 |
0.373
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.372
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.372
|
Human |
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.371
|
|
|
|
positive regulation of fat cell differentiation
|
GO:0045600 |
32 |
0.371
|
|
|
|
regulation of vitamin d biosynthetic process
|
GO:0060556 |
1 |
0.370
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.369
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.369
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.368
|
Worm |
|
|
regulation of fat cell differentiation
|
GO:0045598 |
81 |
0.368
|
|
|
|
response to ammonium ion
|
GO:0060359 |
21 |
0.362
|
Fly |
|
|
lymphocyte apoptotic process
|
GO:0070227 |
54 |
0.361
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.361
|
Human |
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.360
|
|
|
|
regulation of androgen receptor signaling pathway
|
GO:0060765 |
3 |
0.360
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.355
|
Mouse |
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.354
|
|
|
|
response to alkaloid
|
GO:0043279 |
34 |
0.353
|
Fly |
|
|
forebrain development
|
GO:0030900 |
302 |
0.352
|
|
|
|
fat soluble vitamin biosynthetic process
|
GO:0042362 |
4 |
0.345
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.344
|
Human |
|
|
fatty acid catabolic process
|
GO:0009062 |
25 |
0.342
|
|
|
|
mammary gland involution
|
GO:0060056 |
9 |
0.342
|
|
|
|
cerebellar granule cell precursor proliferation
|
GO:0021930 |
10 |
0.341
|
|
|
|
nitric oxide biosynthetic process
|
GO:0006809 |
25 |
0.340
|
Human |
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.340
|
Mouse Rat |
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.336
|
Human |
|
|
monosaccharide transport
|
GO:0015749 |
58 |
0.330
|
Human |
|
|
carbohydrate homeostasis
|
GO:0033500 |
128 |
0.329
|
Human Rat |
|
|
response to hypoxia
|
GO:0001666 |
58 |
0.326
|
|
|
|
memory
|
GO:0007613 |
58 |
0.324
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.323
|
Human |
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.321
|
Rat |
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
40 |
0.316
|
Mouse |
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.316
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.314
|
|
|
|
intracellular steroid hormone receptor signaling pathway
|
GO:0030518 |
29 |
0.311
|
|
|
|
heart contraction
|
GO:0060047 |
93 |
0.310
|
|
|
|
prostate gland development
|
GO:0030850 |
48 |
0.310
|
Mouse |
|
|
regulation of appetite
|
GO:0032098 |
12 |
0.310
|
|
|
|
multi organism reproductive behavior
|
GO:0044705 |
29 |
0.309
|
Fly |
|
|
white fat cell differentiation
|
GO:0050872 |
15 |
0.306
|
|
|
|
carbohydrate catabolic process
|
GO:0016052 |
32 |
0.304
|
Human |
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.301
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.301
|
|
|
|
positive regulation of apoptotic process involved in morphogenesis
|
GO:1902339 |
4 |
0.300
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.299
|
|
|
|
fatty acid oxidation
|
GO:0019395 |
28 |
0.298
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.298
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.297
|
|
|
|
hindbrain development
|
GO:0030902 |
128 |
0.293
|
|
|
|
germ line stem cell division
|
GO:0042078 |
2 |
0.289
|
Fly |
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.288
|
Mouse |
|
|
nuclear transport
|
GO:0051169 |
139 |
0.287
|
Worm |
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.282
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.280
|
|
|
|
b cell proliferation
|
GO:0042100 |
53 |
0.280
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.277
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.274
|
|
|
|
positive regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014068 |
20 |
0.274
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.273
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.266
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.265
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.265
|
|
|
|
positive regulation of mammary gland involution
|
GO:1903521 |
4 |
0.260
|
|
|
|
appendage development
|
GO:0048736 |
166 |
0.259
|
|
|
|
fatty acid beta oxidation
|
GO:0006635 |
16 |
0.257
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.256
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.255
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.251
|
Human |
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.251
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.251
|
|
|
|
negative regulation of release of cytochrome c from mitochondria
|
GO:0090201 |
6 |
0.250
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.249
|
|
|
|
prostate gland epithelium morphogenesis
|
GO:0060740 |
31 |
0.245
|
Mouse |
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.244
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.242
|
Mouse |
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.242
|
|
|
|
adult behavior
|
GO:0030534 |
135 |
0.242
|
|
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
56 |
0.241
|
Human Mouse |
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.239
|
|
|
|
cellular amide metabolic process
|
GO:0043603 |
58 |
0.236
|
|
|
|
feeding behavior
|
GO:0007631 |
62 |
0.235
|
Fly |
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.235
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.234
|
Worm |
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.230
|
|
|
|
hexose transport
|
GO:0008645 |
56 |
0.230
|
Human |
|
|
t cell activation
|
GO:0042110 |
289 |
0.230
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.229
|
|
|
|
organic acid catabolic process
|
GO:0016054 |
51 |
0.228
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.228
|
|
|
|
response to food
|
GO:0032094 |
17 |
0.227
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.227
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.227
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.225
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.224
|
Fly |
|
|
organophosphate biosynthetic process
|
GO:0090407 |
122 |
0.224
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
24 |
0.222
|
Worm Fly |
|
|
regulation of fatty acid beta oxidation
|
GO:0031998 |
1 |
0.222
|
|
|
|
carboxylic acid catabolic process
|
GO:0046395 |
51 |
0.221
|
|
|
|
methylation
|
GO:0032259 |
134 |
0.221
|
|
|
|
regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014066 |
30 |
0.219
|
|
|
|
branching involved in mammary gland duct morphogenesis
|
GO:0060444 |
27 |
0.219
|
|
|
|
positive regulation of gluconeogenesis
|
GO:0045722 |
11 |
0.219
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.219
|
|
|
|
response to cocaine
|
GO:0042220 |
14 |
0.219
|
Fly |
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.216
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.216
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.215
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
56 |
0.215
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.215
|
|
|
|
g protein coupled acetylcholine receptor signaling pathway
|
GO:0007213 |
4 |
0.211
|
|
|
|
sulfur compound metabolic process
|
GO:0006790 |
100 |
0.211
|
|
|
|
steroid biosynthetic process
|
GO:0006694 |
47 |
0.210
|
|
|
|
regulation of mammary gland involution
|
GO:1903519 |
4 |
0.210
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.208
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.208
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.207
|
|
|
|
sensory perception of umami taste
|
GO:0050917 |
4 |
0.206
|
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.206
|
Fly |
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.205
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.203
|
|
|
|
nitric oxide metabolic process
|
GO:0046209 |
25 |
0.202
|
Human |
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.202
|
|
|
|
circadian behavior
|
GO:0048512 |
13 |
0.198
|
Fly |
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.197
|
|
|
|
cellular response to bile acid
|
GO:1903413 |
1 |
0.193
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.192
|
|
|
|
regulation of glucose import
|
GO:0046324 |
26 |
0.192
|
Human |
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.192
|
Rat |
|
|
negative regulation of blood pressure
|
GO:0045776 |
22 |
0.192
|
|
|
|
exocrine pancreas development
|
GO:0031017 |
7 |
0.192
|
|
|
|
positive regulation of peptide secretion
|
GO:0002793 |
33 |
0.191
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.191
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
65 |
0.190
|
Mouse |
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
56 |
0.190
|
Mouse |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.189
|
Rat |
|
|
neuropeptide signaling pathway
|
GO:0007218 |
19 |
0.189
|
|
|
|
positive regulation of lipid biosynthetic process
|
GO:0046889 |
18 |
0.187
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.186
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.186
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.184
|
Worm |
|
|
regulation of release of cytochrome c from mitochondria
|
GO:0090199 |
11 |
0.184
|
|
|
|
pyruvate metabolic process
|
GO:0006090 |
28 |
0.183
|
Human |
|
|
vascular process in circulatory system
|
GO:0003018 |
62 |
0.183
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.183
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.182
|
|
|
|
neural precursor cell proliferation
|
GO:0061351 |
121 |
0.181
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.181
|
|
|
|
catecholamine metabolic process
|
GO:0006584 |
30 |
0.180
|
|
|
|
positive regulation of fatty acid metabolic process
|
GO:0045923 |
8 |
0.180
|
|
|
|
regulation of catecholamine secretion
|
GO:0050433 |
12 |
0.180
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.179
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.176
|
|
|
|
positive regulation of lipid catabolic process
|
GO:0050996 |
6 |
0.174
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.172
|
|
|
|
glycerolipid biosynthetic process
|
GO:0045017 |
50 |
0.170
|
|
|
|
diacylglycerol metabolic process
|
GO:0046339 |
6 |
0.168
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
11 |
0.168
|
Worm Fly |
|
|
lipid localization
|
GO:0010876 |
126 |
0.167
|
Worm |
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.166
|
|
|
|
jak stat cascade
|
GO:0007259 |
42 |
0.166
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.166
|
|
|
|
maternal process involved in female pregnancy
|
GO:0060135 |
32 |
0.164
|
|
|
|
response to purine containing compound
|
GO:0014074 |
28 |
0.161
|
|
|
|
fatty acid transport
|
GO:0015908 |
28 |
0.161
|
|
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
81 |
0.160
|
|
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
59 |
0.160
|
|
|
|
anagen
|
GO:0042640 |
13 |
0.159
|
|
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
41 |
0.159
|
|
|
|
response to corticosteroid
|
GO:0031960 |
20 |
0.159
|
Rat |
|
|
negative regulation of cell growth
|
GO:0030308 |
44 |
0.159
|
|
|
|
circadian sleep wake cycle
|
GO:0042745 |
5 |
0.158
|
Fly |
|
|
regulation of monooxygenase activity
|
GO:0032768 |
7 |
0.157
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.156
|
Fly |
|
|
skeletal system development
|
GO:0001501 |
356 |
0.155
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.155
|
Human |
|
|
regulation of lymphocyte apoptotic process
|
GO:0070228 |
41 |
0.155
|
|
|
|
cell proliferation in external granule layer
|
GO:0021924 |
10 |
0.154
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.153
|
|
|
|
positive regulation of glial cell proliferation
|
GO:0060252 |
4 |
0.153
|
|
|
|
ribose phosphate biosynthetic process
|
GO:0046390 |
59 |
0.151
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.150
|
|
|
|
glutamine metabolic process
|
GO:0006541 |
8 |
0.149
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.148
|
|
|
|
positive regulation of lipid kinase activity
|
GO:0090218 |
11 |
0.148
|
|
|
|
regulation of myotube differentiation
|
GO:0010830 |
62 |
0.148
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.147
|
Rat |
|
|
cell maturation
|
GO:0048469 |
127 |
0.145
|
Fly |
|
|
glutamine family amino acid metabolic process
|
GO:0009064 |
15 |
0.144
|
|
|
|
organic anion transport
|
GO:0015711 |
137 |
0.142
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.142
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.141
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.141
|
|
|
|
mammary gland morphogenesis
|
GO:0060443 |
54 |
0.141
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
65 |
0.141
|
|
|
|
vasoconstriction
|
GO:0042310 |
27 |
0.140
|
|
|
|
activation of janus kinase activity
|
GO:0042976 |
2 |
0.140
|
|
|
|
g protein coupled receptor internalization
|
GO:0002031 |
3 |
0.138
|
|
|
|
regulation of carbohydrate catabolic process
|
GO:0043470 |
12 |
0.138
|
Human |
|
|
glutamate metabolic process
|
GO:0006536 |
9 |
0.135
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.135
|
|
|
|
negative regulation of glycogen biosynthetic process
|
GO:0045719 |
1 |
0.134
|
|
|
|
regulation of tor signaling
|
GO:0032006 |
17 |
0.134
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.134
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.133
|
|
|
|
positive regulation of cellular response to insulin stimulus
|
GO:1900078 |
9 |
0.133
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.132
|
|
|
|
associative learning
|
GO:0008306 |
61 |
0.132
|
|
|
|
regulation of receptor activity
|
GO:0010469 |
41 |
0.131
|
|
|
|
cellular response to hypoxia
|
GO:0071456 |
17 |
0.131
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
53 |
0.130
|
|
|
|
germline stem cell asymmetric division
|
GO:0098728 |
2 |
0.129
|
Fly |
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.129
|
Human |
|
|
regulation of binding
|
GO:0051098 |
111 |
0.129
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.129
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.129
|
Mouse Fly |
|
|
visual learning
|
GO:0008542 |
44 |
0.126
|
|
|
|
lung epithelium development
|
GO:0060428 |
37 |
0.126
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.126
|
|
|
|
negative regulation of tyrosine phosphorylation of stat protein
|
GO:0042532 |
3 |
0.126
|
|
|
|
columnar cuboidal epithelial cell differentiation
|
GO:0002065 |
82 |
0.126
|
Mouse |
|
|
drug metabolic process
|
GO:0017144 |
4 |
0.125
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.125
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
87 |
0.125
|
|
|
|
negative regulation of peptidyl tyrosine phosphorylation
|
GO:0050732 |
17 |
0.125
|
|
|
|
acylglycerol biosynthetic process
|
GO:0046463 |
18 |
0.123
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
11 |
0.122
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.121
|
Worm |
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
59 |
0.120
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.120
|
Human |
|
|
lung cell differentiation
|
GO:0060479 |
30 |
0.120
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.120
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.120
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.120
|
|
|
|
cellular response to starvation
|
GO:0009267 |
57 |
0.119
|
Worm |
|
|
ossification
|
GO:0001503 |
216 |
0.119
|
|
|
|
cellular response to oxygen levels
|
GO:0071453 |
20 |
0.119
|
|
|
|
regulation of nucleotide biosynthetic process
|
GO:0030808 |
34 |
0.119
|
|
|
|
central nervous system neuron differentiation
|
GO:0021953 |
162 |
0.117
|
|
|
|
lipid storage
|
GO:0019915 |
36 |
0.117
|
Worm |
|
|
smooth muscle contraction
|
GO:0006939 |
44 |
0.116
|
|
|
|
digestion
|
GO:0007586 |
40 |
0.116
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.115
|
|
|
|
nitrogen cycle metabolic process
|
GO:0071941 |
3 |
0.113
|
|
|
|
regulation of steroid hormone biosynthetic process
|
GO:0090030 |
4 |
0.112
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
64 |
0.112
|
|
|
|
prostate gland stromal morphogenesis
|
GO:0060741 |
2 |
0.112
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.112
|
|
|
|
intestinal absorption
|
GO:0050892 |
13 |
0.112
|
|
|
|
prostate gland morphogenesis
|
GO:0060512 |
32 |
0.111
|
Mouse |
|
|
epithelial cell migration
|
GO:0010631 |
63 |
0.111
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
76 |
0.111
|
|
