Mus musculus

0 known processes

Ints5

integrator complex subunit 5

(Aliases: mKIAA1698,1110055N21Rik)

Ints5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular ketone metabolic process GO:0042180 84 0.114
oxidation reduction process GO:0055114 342 0.107
regulation of cellular ketone metabolic process GO:0010565 66 0.106
negative regulation of molecular function GO:0044092 258 0.086
regulation of organelle organization GO:0033043 289 0.082
negative regulation of protein modification process GO:0031400 163 0.067
ossification GO:0001503 216 0.065
nucleobase containing small molecule metabolic process GO:0055086 352 0.063
regulation of hydrolase activity GO:0051336 246 0.059
macromolecule catabolic process GO:0009057 281 0.058
cellular amino acid metabolic process GO:0006520 103 0.056
amine metabolic process GO:0009308 45 0.055
negative regulation of intracellular signal transduction GO:1902532 167 0.055
transmembrane transport GO:0055085 412 0.050
cellular amine metabolic process GO:0044106 44 0.050
proteasomal protein catabolic process GO:0010498 98 0.049
generation of precursor metabolites and energy GO:0006091 103 0.046
purine containing compound biosynthetic process GO:0072522 70 0.045
rhythmic process GO:0048511 174 0.045
multicellular organismal homeostasis GO:0048871 164 0.044
regulation of protein kinase activity GO:0045859 232 0.043
purine nucleotide metabolic process GO:0006163 302 0.042
protein catabolic process GO:0030163 221 0.042
leukocyte differentiation GO:0002521 342 0.042
retrograde transport endosome to golgi GO:0042147 2 0.042
metal ion homeostasis GO:0055065 189 0.040
ribonucleotide metabolic process GO:0009259 291 0.040
negative regulation of cellular amine metabolic process GO:0033239 1 0.040
positive regulation of organelle organization GO:0010638 128 0.040
protein modification by small protein conjugation or removal GO:0070647 207 0.039
dna dealkylation GO:0035510 11 0.038
cytoplasmic transport GO:0016482 234 0.037
regulation of mammary gland epithelial cell proliferation GO:0033599 12 0.037
negative regulation of protein metabolic process GO:0051248 282 0.036
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.036
positive regulation of hydrolase activity GO:0051345 148 0.036
organonitrogen compound biosynthetic process GO:1901566 192 0.036
negative regulation of phosphate metabolic process GO:0045936 184 0.035
dna metabolic process GO:0006259 303 0.034
regulation of cellular amine metabolic process GO:0033238 20 0.034
purine containing compound metabolic process GO:0072521 311 0.034
negative regulation of cellular protein metabolic process GO:0032269 247 0.033
histone methylation GO:0016571 71 0.033
cellular homeostasis GO:0019725 240 0.033
actin cytoskeleton organization GO:0030036 220 0.032
regulation of mitochondrion organization GO:0010821 27 0.032
ribose phosphate metabolic process GO:0019693 291 0.032
sensory perception GO:0007600 245 0.031
negative regulation of cell proliferation GO:0008285 296 0.031
negative regulation of protein phosphorylation GO:0001933 126 0.031
regulation of cellular catabolic process GO:0031329 242 0.031
homeostasis of number of cells GO:0048872 210 0.031
peptidyl amino acid modification GO:0018193 336 0.031
regulation of cellular amino acid metabolic process GO:0006521 5 0.030
negative regulation of kinase activity GO:0033673 81 0.030
negative regulation of phosphorylation GO:0042326 166 0.029
regulation of transferase activity GO:0051338 263 0.029
apoptotic signaling pathway GO:0097190 306 0.029
regulation of protein localization GO:0032880 231 0.029
cellular macromolecule catabolic process GO:0044265 206 0.028
protein targeting GO:0006605 143 0.028
negative regulation of transferase activity GO:0051348 85 0.028
signal transduction by p53 class mediator GO:0072331 51 0.028
skeletal system development GO:0001501 356 0.027
negative regulation of phosphorus metabolic process GO:0010563 184 0.027
axonogenesis GO:0007409 274 0.027
nucleoside triphosphate metabolic process GO:0009141 230 0.027
mitochondrion organization GO:0007005 134 0.027
regulation of anatomical structure size GO:0090066 178 0.027
cation transport GO:0006812 399 0.027
development of primary sexual characteristics GO:0045137 143 0.027
myeloid cell differentiation GO:0030099 233 0.027
purine nucleoside catabolic process GO:0006152 205 0.026
purine ribonucleoside metabolic process GO:0046128 241 0.026
demethylation GO:0070988 23 0.026
purine nucleoside triphosphate metabolic process GO:0009144 226 0.026
telencephalon development GO:0021537 186 0.025
glycosyl compound metabolic process GO:1901657 246 0.025
glucose homeostasis GO:0042593 128 0.025
muscle tissue development GO:0060537 308 0.025
purine ribonucleotide metabolic process GO:0009150 290 0.025
regulation of nucleoside metabolic process GO:0009118 130 0.025
cellular response to dna damage stimulus GO:0006974 207 0.024
regulation of homeostatic process GO:0032844 182 0.024
circadian regulation of gene expression GO:0032922 48 0.024
purine nucleoside metabolic process GO:0042278 241 0.024
calcium ion homeostasis GO:0055074 127 0.024
dephosphorylation GO:0016311 129 0.024
cellular response to cytokine stimulus GO:0071345 189 0.024
tissue remodeling GO:0048771 102 0.024
posttranscriptional regulation of gene expression GO:0010608 155 0.023
cation homeostasis GO:0055080 212 0.023
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.023
regulation of neuron differentiation GO:0045664 281 0.023
regulation of purine nucleotide metabolic process GO:1900542 169 0.023
ion transmembrane transport GO:0034220 361 0.023
positive regulation of nucleotide metabolic process GO:0045981 114 0.022
hematopoietic progenitor cell differentiation GO:0002244 143 0.022
modification dependent macromolecule catabolic process GO:0043632 133 0.022
positive regulation of protein modification process GO:0031401 299 0.021
mitotic cell cycle GO:0000278 195 0.021
positive regulation of cellular amine metabolic process GO:0033240 5 0.021
organophosphate biosynthetic process GO:0090407 122 0.021
circadian rhythm GO:0007623 114 0.021
nucleoside phosphate biosynthetic process GO:1901293 79 0.021
protein import into nucleus GO:0006606 95 0.021
tissue homeostasis GO:0001894 115 0.020
protein localization to nucleus GO:0034504 121 0.020
positive regulation of growth GO:0045927 104 0.020
multi multicellular organism process GO:0044706 109 0.020
regulation of kinase activity GO:0043549 249 0.020
regulation of cell cycle GO:0051726 281 0.020
carbohydrate homeostasis GO:0033500 128 0.020
energy derivation by oxidation of organic compounds GO:0015980 77 0.020
regulation of intracellular transport GO:0032386 159 0.020
wnt signaling pathway GO:0016055 188 0.020
camera type eye development GO:0043010 266 0.019
ribonucleoside triphosphate metabolic process GO:0009199 220 0.019
cellular protein catabolic process GO:0044257 155 0.019
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.019
protein ubiquitination GO:0016567 171 0.019
regulation of protein transport GO:0051223 163 0.019
endocytosis GO:0006897 168 0.019
response to light stimulus GO:0009416 135 0.019
cleavage involved in rrna processing GO:0000469 1 0.019
chemotaxis GO:0006935 247 0.019
nucleotide metabolic process GO:0009117 332 0.019
vitamin d receptor signaling pathway GO:0070561 2 0.019
positive regulation of mitochondrion organization GO:0010822 17 0.018
nucleoside phosphate metabolic process GO:0006753 338 0.018
cellular carbohydrate metabolic process GO:0044262 119 0.018
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.018
mrna metabolic process GO:0016071 84 0.018
nitrogen compound transport GO:0071705 271 0.018
purine nucleotide biosynthetic process GO:0006164 65 0.018
nuclear transport GO:0051169 139 0.018
single organism nuclear import GO:1902593 95 0.018
regulation of leukocyte differentiation GO:1902105 159 0.018
nucleobase biosynthetic process GO:0046112 3 0.018
male gamete generation GO:0048232 285 0.018
small gtpase mediated signal transduction GO:0007264 97 0.018
epithelial cell proliferation GO:0050673 174 0.018
response to organonitrogen compound GO:0010243 246 0.017
spermatogenesis GO:0007283 284 0.017
divalent inorganic cation homeostasis GO:0072507 138 0.017
cell type specific apoptotic process GO:0097285 268 0.017
ribonucleoside metabolic process GO:0009119 245 0.017
regulation of nucleotide metabolic process GO:0006140 169 0.017
response to reactive oxygen species GO:0000302 56 0.017
regulation of histone methylation GO:0031060 30 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.017
maturation of ssu rrna GO:0030490 1 0.017
embryonic organ morphogenesis GO:0048562 276 0.017
rna interference GO:0016246 2 0.017
rna processing GO:0006396 105 0.017
cellular response to external stimulus GO:0071496 88 0.017
regulation of endopeptidase activity GO:0052548 89 0.017
positive regulation of programmed cell death GO:0043068 218 0.017
regulation of apoptotic signaling pathway GO:2001233 197 0.017
regulation of protein serine threonine kinase activity GO:0071900 157 0.017
regulation of circadian rhythm GO:0042752 58 0.017
positive regulation of cell development GO:0010720 237 0.017
maintenance of location GO:0051235 89 0.017
regulation of nucleotide catabolic process GO:0030811 122 0.016
protein localization to organelle GO:0033365 185 0.016
g protein coupled receptor signaling pathway GO:0007186 243 0.016
cytokine production GO:0001816 319 0.016
cellular response to extracellular stimulus GO:0031668 81 0.016
epithelial tube morphogenesis GO:0060562 303 0.016
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.016
regulation of myeloid cell differentiation GO:0045637 96 0.016
skeletal system morphogenesis GO:0048705 203 0.016
embryonic placenta development GO:0001892 98 0.016
myeloid leukocyte differentiation GO:0002573 119 0.016
nucleoside metabolic process GO:0009116 246 0.016
regulation of atp metabolic process GO:1903578 17 0.016
digestive tract development GO:0048565 190 0.016
response to nutrient levels GO:0031667 109 0.015
nucleocytoplasmic transport GO:0006913 139 0.015
placenta development GO:0001890 140 0.015
protein maturation GO:0051604 176 0.015
dna modification GO:0006304 50 0.015
response to peptide GO:1901652 136 0.015
gland development GO:0048732 330 0.015
regulation of epithelial cell proliferation GO:0050678 141 0.015
carbohydrate derivative catabolic process GO:1901136 231 0.015
organ growth GO:0035265 117 0.015
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000466 1 0.015
nucleotide biosynthetic process GO:0009165 78 0.015
cellular response to growth factor stimulus GO:0071363 197 0.015
multicellular organism growth GO:0035264 161 0.015
lipid homeostasis GO:0055088 63 0.015
regulation of establishment of protein localization GO:0070201 181 0.015
regulation of peptidase activity GO:0052547 96 0.015
bone remodeling GO:0046849 53 0.015
cellular response to peptide hormone stimulus GO:0071375 92 0.015
cell cycle arrest GO:0007050 37 0.015
developmental growth involved in morphogenesis GO:0060560 138 0.015
peptide transport GO:0015833 133 0.014
protein modification by small protein conjugation GO:0032446 187 0.014
heterocycle catabolic process GO:0046700 280 0.014
purine ribonucleotide biosynthetic process GO:0009152 59 0.014
osteoclast differentiation GO:0030316 62 0.014
methylation GO:0032259 134 0.014
positive regulation of nucleoside metabolic process GO:0045979 91 0.014
regulation of ossification GO:0030278 112 0.014
negative regulation of protein maturation GO:1903318 79 0.014
respiratory tube development GO:0030323 167 0.014
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.014
t cell differentiation GO:0030217 174 0.014
genetic imprinting GO:0071514 27 0.014
actin filament organization GO:0007015 113 0.014
intrinsic apoptotic signaling pathway GO:0097193 132 0.014
male meiosis GO:0007140 37 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.014
blastocyst growth GO:0001832 23 0.014
regulation of secretion by cell GO:1903530 249 0.014
striated muscle tissue development GO:0014706 293 0.014
connective tissue development GO:0061448 179 0.013
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.013
regulation of transcription by chromatin organization GO:0034401 0 0.013
microtubule based process GO:0007017 236 0.013
histone lysine methylation GO:0034968 50 0.013
anatomical structure homeostasis GO:0060249 145 0.013
mapk cascade GO:0000165 281 0.013
canonical wnt signaling pathway GO:0060070 130 0.013
fat cell differentiation GO:0045444 160 0.013
response to acid chemical GO:0001101 111 0.013
hexose metabolic process GO:0019318 98 0.013
response to extracellular stimulus GO:0009991 127 0.013
regulation of ion transmembrane transport GO:0034765 119 0.013
protein processing GO:0016485 163 0.013
regulation of cellular response to stress GO:0080135 159 0.013
positive regulation of cellular catabolic process GO:0031331 148 0.013
carbohydrate derivative biosynthetic process GO:1901137 183 0.013
divalent inorganic cation transport GO:0072511 178 0.013
regulation of myeloid leukocyte differentiation GO:0002761 58 0.013
negative regulation of growth GO:0045926 99 0.012
cell adhesion GO:0007155 329 0.012
negative regulation of mapk cascade GO:0043409 65 0.012
reactive oxygen species metabolic process GO:0072593 84 0.012
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.012
response to oxygen levels GO:0070482 62 0.012
regulation of cellular component size GO:0032535 121 0.012
regulation of neuron projection development GO:0010975 169 0.012
regulation of generation of precursor metabolites and energy GO:0043467 38 0.012
cellular chemical homeostasis GO:0055082 215 0.012
protein oligomerization GO:0051259 67 0.012
hormone secretion GO:0046879 128 0.012
regulation of lymphocyte activation GO:0051249 240 0.012
cellular protein complex assembly GO:0043623 116 0.012
atp metabolic process GO:0046034 75 0.012
cell activation involved in immune response GO:0002263 126 0.012
ribonucleotide biosynthetic process GO:0009260 59 0.012
regulation of ion transport GO:0043269 215 0.012
regulation of ras protein signal transduction GO:0046578 114 0.012
negative regulation of cell cycle GO:0045786 123 0.012
negative regulation of apoptotic signaling pathway GO:2001234 104 0.012
guanosine containing compound catabolic process GO:1901069 144 0.012
positive regulation of homeostatic process GO:0032846 64 0.012
regulation of binding GO:0051098 111 0.012
forebrain development GO:0030900 302 0.012
regulation of secretion GO:0051046 274 0.012
morphogenesis of a branching epithelium GO:0061138 193 0.012
monosaccharide metabolic process GO:0005996 106 0.012
positive regulation of cellular respiration GO:1901857 3 0.012
negative regulation of rna splicing GO:0033119 12 0.012
regulation of mapk cascade GO:0043408 248 0.012
regulation of proteolysis GO:0030162 164 0.012
positive regulation of phosphatase activity GO:0010922 4 0.012
carbohydrate biosynthetic process GO:0016051 74 0.012
negative regulation of ossification GO:0030279 49 0.011
positive regulation of chromosome segregation GO:0051984 4 0.011
epithelial cell development GO:0002064 159 0.011
compound eye development GO:0048749 1 0.011
innate immune response GO:0045087 157 0.011
divalent metal ion transport GO:0070838 172 0.011
multicellular organismal signaling GO:0035637 91 0.011
nuclear import GO:0051170 95 0.011
positive regulation of cell death GO:0010942 224 0.011
locomotory behavior GO:0007626 195 0.011
mammary gland epithelium development GO:0061180 65 0.011
regulation of transmembrane transport GO:0034762 128 0.011
cellular divalent inorganic cation homeostasis GO:0072503 127 0.011
b cell activation GO:0042113 161 0.011
regulation of hormone levels GO:0010817 211 0.011
sensory perception of mechanical stimulus GO:0050954 107 0.011
rrna transcription GO:0009303 9 0.011
myeloid cell homeostasis GO:0002262 114 0.011
neuron death GO:0070997 154 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.011
establishment or maintenance of cell polarity GO:0007163 86 0.011
regulation of cysteine type endopeptidase activity GO:2000116 65 0.011
germ cell development GO:0007281 185 0.011
regulation of cytokine production GO:0001817 266 0.011
macromolecule methylation GO:0043414 120 0.011
maternal process involved in female pregnancy GO:0060135 32 0.011
positive regulation of leukocyte differentiation GO:1902107 86 0.011
regulation of protein import into nucleus GO:0042306 52 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.011
peptide secretion GO:0002790 114 0.011
regulation of muscle tissue development GO:1901861 97 0.011
nucleoside biosynthetic process GO:0009163 21 0.011
regulation of cell motility GO:2000145 236 0.011
anion transport GO:0006820 177 0.011
ras protein signal transduction GO:0007265 77 0.011
response to radiation GO:0009314 165 0.011
t cell activation GO:0042110 289 0.011
cellular ion homeostasis GO:0006873 165 0.011
response to growth factor GO:0070848 198 0.011
maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000463 1 0.011
regulation of feeding behavior GO:0060259 3 0.011
bone resorption GO:0045453 38 0.011
skin development GO:0043588 220 0.011
cellular response to organonitrogen compound GO:0071417 145 0.011
organic cyclic compound catabolic process GO:1901361 295 0.010
regulation of cell cycle process GO:0010564 160 0.010
stem cell differentiation GO:0048863 268 0.010
insulin secretion GO:0030073 89 0.010
cellular response to acid chemical GO:0071229 68 0.010
leukocyte activation involved in immune response GO:0002366 126 0.010
negative regulation of proteolysis GO:0045861 74 0.010
peptide hormone secretion GO:0030072 109 0.010
sensory organ morphogenesis GO:0090596 242 0.010
adult behavior GO:0030534 135 0.010
blood circulation GO:0008015 195 0.010
amide transport GO:0042886 138 0.010
endonucleolytic cleavage involved in rrna processing GO:0000478 1 0.010
energy homeostasis GO:0097009 15 0.010
positive regulation of nucleotide biosynthetic process GO:0030810 26 0.010
negative regulation of cytokine production GO:0001818 84 0.010
response to lipopolysaccharide GO:0032496 128 0.010
ribose phosphate biosynthetic process GO:0046390 59 0.010
regulation of protein catabolic process GO:0042176 108 0.010
adaptive immune response GO:0002250 155 0.010
regulation of actin filament based process GO:0032970 99 0.010

Ints5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.024
organ system cancer DOID:0050686 0 0.024
cancer DOID:162 0 0.024
disease of anatomical entity DOID:7 0 0.014
nervous system disease DOID:863 0 0.014
gastrointestinal system cancer DOID:3119 0 0.013
intestinal cancer DOID:10155 0 0.013
large intestine cancer DOID:5672 0 0.011