|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.971
|
Mouse |
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.959
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
83 |
0.954
|
Mouse |
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.946
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.937
|
Mouse |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.920
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.911
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.910
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.877
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.877
|
|
|
|
regulation of defense response to virus by host
|
GO:0050691 |
8 |
0.857
|
Mouse |
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.850
|
|
|
|
negative regulation of interleukin 2 production
|
GO:0032703 |
8 |
0.841
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.823
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.821
|
|
|
|
defense response to virus
|
GO:0051607 |
68 |
0.810
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.810
|
Mouse |
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.807
|
Mouse |
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
83 |
0.803
|
Mouse |
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.803
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
68 |
0.801
|
Mouse |
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.770
|
Mouse |
|
|
defense response to gram negative bacterium
|
GO:0050829 |
28 |
0.764
|
|
|
|
defense response to gram positive bacterium
|
GO:0050830 |
50 |
0.744
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.733
|
Mouse |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.731
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.707
|
Mouse |
|
|
t helper cell differentiation
|
GO:0042093 |
28 |
0.704
|
Mouse |
|
|
antibacterial peptide production
|
GO:0002778 |
2 |
0.704
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.702
|
|
|
|
response to protozoan
|
GO:0001562 |
28 |
0.698
|
Mouse |
|
|
response to type i interferon
|
GO:0034340 |
12 |
0.697
|
Mouse |
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.692
|
|
|
|
defense response to protozoan
|
GO:0042832 |
25 |
0.687
|
Mouse |
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.686
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.682
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.681
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.669
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.664
|
Mouse |
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.659
|
Mouse |
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.659
|
Mouse |
|
|
antigen processing and presentation
|
GO:0019882 |
47 |
0.649
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.647
|
Mouse |
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.640
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.640
|
Mouse |
|
|
regulation of tolerance induction dependent upon immune response
|
GO:0002652 |
1 |
0.637
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.619
|
|
|
|
regulation of defense response to bacterium
|
GO:1900424 |
3 |
0.614
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.612
|
|
|
|
alpha beta t cell differentiation involved in immune response
|
GO:0002293 |
30 |
0.599
|
Mouse |
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.596
|
|
|
|
regulation of interleukin 2 production
|
GO:0032663 |
28 |
0.587
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.576
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.571
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.569
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.551
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.544
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.543
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.541
|
|
|
|
response to interferon gamma
|
GO:0034341 |
34 |
0.525
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.523
|
|
|
|
regulation of t cell mediated immunity
|
GO:0002709 |
34 |
0.518
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
61 |
0.512
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.500
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.497
|
Mouse |
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.483
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.478
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.477
|
Mouse |
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
61 |
0.471
|
|
|
|
regulation of symbiosis encompassing mutualism through parasitism
|
GO:0043903 |
52 |
0.463
|
Mouse |
|
|
antimicrobial peptide production
|
GO:0002775 |
2 |
0.462
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.461
|
|
|
|
interleukin 1 beta production
|
GO:0032611 |
30 |
0.457
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.455
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.440
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.431
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.429
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.423
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
49 |
0.422
|
|
|
|
regulation of myd88 independent toll like receptor signaling pathway
|
GO:0034127 |
1 |
0.422
|
Mouse |
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.421
|
Mouse |
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.409
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.394
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.394
|
Mouse |
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.387
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.386
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.385
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.379
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
61 |
0.376
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.374
|
|
|
|
regulation of antimicrobial humoral response
|
GO:0002759 |
3 |
0.367
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.366
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.365
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.362
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.362
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
55 |
0.360
|
Mouse |
|
|
negative regulation of natural killer cell mediated immunity
|
GO:0002716 |
5 |
0.353
|
|
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.349
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.343
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.338
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.336
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.328
|
|
|
|
cellular amide metabolic process
|
GO:0043603 |
58 |
0.327
|
|
|
|
t cell mediated immunity
|
GO:0002456 |
50 |
0.327
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.321
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.318
|
Mouse |
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
57 |
0.317
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.316
|
|
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.314
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.314
|
Mouse |
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.310
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.308
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.302
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.302
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.300
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.300
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.297
|
|
|
|
cellular response to interferon gamma
|
GO:0071346 |
25 |
0.294
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.293
|
|
|
|
viral process
|
GO:0016032 |
41 |
0.291
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.288
|
Mouse |
|
|
humoral immune response
|
GO:0006959 |
57 |
0.286
|
|
|
|
somatic diversification of immunoglobulins involved in immune response
|
GO:0002208 |
36 |
0.282
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.281
|
|
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
38 |
0.277
|
Mouse |
|
|
regulation of type i interferon mediated signaling pathway
|
GO:0060338 |
7 |
0.274
|
Mouse |
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.269
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.268
|
Mouse |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.267
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.264
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.263
|
|
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
39 |
0.256
|
Mouse |
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.256
|
Mouse |
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.256
|
|
|
|
negative regulation of inflammatory response
|
GO:0050728 |
61 |
0.255
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.254
|
|
|
|
interleukin 1 production
|
GO:0032612 |
31 |
0.254
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.252
|
|
|
|
type i interferon signaling pathway
|
GO:0060337 |
10 |
0.250
|
Mouse |
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.250
|
|
|
|
antimicrobial peptide biosynthetic process
|
GO:0002777 |
2 |
0.249
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.248
|
Mouse |
|
|
positive regulation of t cell mediated cytotoxicity
|
GO:0001916 |
15 |
0.247
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.245
|
|
|
|
negative regulation of growth of symbiont in host
|
GO:0044130 |
19 |
0.245
|
Mouse |
|
|
t cell activation involved in immune response
|
GO:0002286 |
43 |
0.241
|
Mouse |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.241
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.240
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.240
|
Mouse |
|
|
regulation of defense response to virus
|
GO:0050688 |
18 |
0.237
|
Mouse |
|
|
positive regulation of interleukin 1 secretion
|
GO:0050716 |
14 |
0.237
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.234
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.234
|
|
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
21 |
0.234
|
|
|
|
viral life cycle
|
GO:0019058 |
36 |
0.230
|
|
|
|
antibacterial peptide biosynthetic process
|
GO:0002780 |
2 |
0.221
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.220
|
|
|
|
cd4 positive alpha beta t cell differentiation involved in immune response
|
GO:0002294 |
28 |
0.218
|
Mouse |
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.216
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.215
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.215
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.214
|
|
|
|
negative regulation of innate immune response
|
GO:0045824 |
17 |
0.214
|
|
|
|
alpha beta t cell activation involved in immune response
|
GO:0002287 |
31 |
0.211
|
Mouse |
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.208
|
|
|
|
regulation of autophagy
|
GO:0010506 |
30 |
0.204
|
|
|
|
b cell activation involved in immune response
|
GO:0002312 |
50 |
0.202
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.201
|
Mouse |
|
|
t helper 1 type immune response
|
GO:0042088 |
25 |
0.198
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.197
|
|
|
|
programmed necrotic cell death
|
GO:0097300 |
28 |
0.194
|
Mouse |
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.193
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.192
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.192
|
|
|
|
positive regulation of antimicrobial peptide production
|
GO:0002225 |
1 |
0.190
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.186
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.185
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.184
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.183
|
|
|
|
antibacterial humoral response
|
GO:0019731 |
8 |
0.181
|
|
|
|
antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway
|
GO:0002484 |
3 |
0.181
|
|
|
|
somatic recombination of immunoglobulin genes involved in immune response
|
GO:0002204 |
36 |
0.178
|
|
|
|
somatic diversification of immunoglobulins
|
GO:0016445 |
43 |
0.175
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.175
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.172
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.172
|
|
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.171
|
Mouse |
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.171
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.170
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.170
|
|
|
|
cellular response to type i interferon
|
GO:0071357 |
10 |
0.168
|
Mouse |
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.168
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.168
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.167
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.166
|
Mouse |
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.166
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.163
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.163
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.160
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.160
|
|
|
|
peptide metabolic process
|
GO:0006518 |
46 |
0.160
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.158
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.157
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.155
|
Mouse |
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.154
|
|
|
|
regulation of natural killer cell mediated cytotoxicity
|
GO:0042269 |
19 |
0.153
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.153
|
Mouse |
|
|
innate immune response activating signal transduction
|
GO:0002758 |
50 |
0.152
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.152
|
Mouse |
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.151
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.150
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.150
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
87 |
0.150
|
|
|
|
negative regulation of t helper 2 cell differentiation
|
GO:0045629 |
4 |
0.149
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.148
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.148
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.148
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.148
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
26 |
0.147
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.146
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.146
|
|
|
|
notch signaling pathway
|
GO:0007219 |
71 |
0.146
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.145
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.144
|
|
|
|
regulation of cd4 positive alpha beta t cell activation
|
GO:2000514 |
24 |
0.142
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.140
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
52 |
0.140
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.139
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.138
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.137
|
|
|
|
positive regulation of t helper 1 cell differentiation
|
GO:0045627 |
4 |
0.136
|
|
|
|
regulation of toll like receptor signaling pathway
|
GO:0034121 |
20 |
0.133
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.133
|
|
|
|
regulation of antibacterial peptide biosynthetic process
|
GO:0002808 |
1 |
0.133
|
|
|
|
autophagy
|
GO:0006914 |
45 |
0.132
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.130
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.129
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.128
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.126
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.126
|
|
|
|
regulation of interleukin 1 beta production
|
GO:0032651 |
25 |
0.126
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.125
|
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
77 |
0.125
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.124
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.121
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.120
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.120
|
|
|
|
histone modification
|
GO:0016570 |
159 |
0.120
|
Mouse |
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.119
|
Human |
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.119
|
|
|
|
cytoplasmic pattern recognition receptor signaling pathway
|
GO:0002753 |
10 |
0.119
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.118
|
|
|
|
regulation of interleukin 1 production
|
GO:0032652 |
26 |
0.118
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
51 |
0.118
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
36 |
0.115
|
|
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.114
|
Mouse |
|
|
regulation of acute inflammatory response
|
GO:0002673 |
27 |
0.114
|
|
|
|
nik nf kappab signaling
|
GO:0038061 |
14 |
0.114
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.113
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.113
|
|
|
|
nucleotide binding oligomerization domain containing signaling pathway
|
GO:0070423 |
6 |
0.113
|
|
|
|
positive regulation of interleukin 12 production
|
GO:0032735 |
21 |
0.112
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
38 |
0.111
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.111
|
|
|
|
negative regulation of t cell proliferation
|
GO:0042130 |
38 |
0.111
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.110
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.109
|
|
|
|
response to amino acid
|
GO:0043200 |
37 |
0.109
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
205 |
0.108
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.107
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
11 |
0.105
|
|
|
|
dna recombination
|
GO:0006310 |
92 |
0.105
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
34 |
0.105
|
|
|
|
b cell mediated immunity
|
GO:0019724 |
71 |
0.105
|
Mouse |
|
|
cd4 positive or cd8 positive alpha beta t cell lineage commitment
|
GO:0043369 |
8 |
0.104
|
Mouse |
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.104
|
|
|
|
immunoglobulin production involved in immunoglobulin mediated immune response
|
GO:0002381 |
43 |
0.101
|
|
|
|
regulation of interleukin 1 beta secretion
|
GO:0050706 |
15 |
0.101
|
|
|
|
response to oxygen levels
|
GO:0070482 |
62 |
0.100
|
|
|
|
t cell differentiation involved in immune response
|
GO:0002292 |
30 |
0.099
|
Mouse |
|
|
positive regulation of antimicrobial peptide biosynthetic process
|
GO:0002807 |
1 |
0.099
|
|
|
|
regulation of type 2 immune response
|
GO:0002828 |
18 |
0.099
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.098
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.098
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
74 |
0.096
|
|
|
|
toll like receptor signaling pathway
|
GO:0002224 |
38 |
0.096
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.094
|
|
|
|
regulation of interleukin 1 secretion
|
GO:0050704 |
15 |
0.094
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.093
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.092
|
|
|
|
isotype switching
|
GO:0045190 |
36 |
0.092
|
|
|
|
body morphogenesis
|
GO:0010171 |
45 |
0.091
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.091
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.091
|
|
|
|
myeloid dendritic cell differentiation
|
GO:0043011 |
16 |
0.091
|
Mouse |
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
50 |
0.091
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.091
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.090
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
40 |
0.089
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.088
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.087
|
|
|
|
interleukin 1 beta secretion
|
GO:0050702 |
16 |
0.087
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.087
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.087
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.086
|
|
|
|
gonad development
|
GO:0008406 |
141 |
0.086
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.086
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.086
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.085
|
|
|
|
regulation of stem cell proliferation
|
GO:0072091 |
78 |
0.084
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.083
|
|
|
|
response to light stimulus
|
GO:0009416 |
135 |
0.083
|
|
|
|
regulation of interleukin 6 production
|
GO:0032675 |
55 |
0.082
|
|
|
|
tyrosine phosphorylation of stat1 protein
|
GO:0042508 |
3 |
0.082
|
|
|
|
extrinsic apoptotic signaling pathway via death domain receptors
|
GO:0008625 |
34 |
0.081
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.080
|
|
|
|
regulation of antimicrobial peptide production
|
GO:0002784 |
1 |
0.079
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.078
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.078
|
Mouse |
|
|
response to peptide
|
GO:1901652 |
136 |
0.078
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
62 |
0.078
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.077
|
|
|
|
somatic diversification of immune receptors via germline recombination within a single locus
|
GO:0002562 |
51 |
0.077
|
|
|
|
negative regulation of lymphocyte mediated immunity
|
GO:0002707 |
21 |
0.076
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
40 |
0.076
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.075
|
|
|
|
stem cell proliferation
|
GO:0072089 |
117 |
0.075
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.075
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.074
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.074
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.074
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.073
|
Mouse |
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
70 |
0.072
|
|
|
|
regulation of antimicrobial peptide biosynthetic process
|
GO:0002805 |
1 |
0.072
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
51 |
0.071
|
|
|
|
regulation of antibacterial peptide production
|
GO:0002786 |
1 |
0.071
|
|
|
|
rna interference
|
GO:0016246 |
2 |
0.071
|
|
|
|
female sex differentiation
|
GO:0046660 |
84 |
0.071
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.071
|
|
|
|
positive regulation of tolerance induction dependent upon immune response
|
GO:0002654 |
1 |
0.071
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.071
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
41 |
0.071
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.070
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.070
|
|
|
|
type i interferon production
|
GO:0032606 |
29 |
0.069
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
42 |
0.069
|
|
|
|
acute inflammatory response
|
GO:0002526 |
41 |
0.069
|
|
|
|
modulation by virus of host morphology or physiology
|
GO:0019048 |
3 |
0.068
|
|
|
|
regulation of t helper 1 cell differentiation
|
GO:0045625 |
7 |
0.068
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.068
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.067
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
49 |
0.067
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.067
|
|
|
|
neural tube development
|
GO:0021915 |
160 |
0.067
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.066
|
|
|
|
regulation of b cell mediated immunity
|
GO:0002712 |
37 |
0.066
|
|
|
|
regulation of notch signaling pathway
|
GO:0008593 |
35 |
0.066
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.066
|
|
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
41 |
0.066
|
Mouse |
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.066
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.065
|
Human |
|
|
response to nicotine
|
GO:0035094 |
6 |
0.065
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
50 |
0.065
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.065
|
|
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
81 |
0.065
|
|
|
|
response to hypoxia
|
GO:0001666 |
58 |
0.065
|
|
|
|
negative regulation of toll like receptor signaling pathway
|
GO:0034122 |
14 |
0.064
|
Mouse |
|
|
negative regulation of inflammatory response to antigenic stimulus
|
GO:0002862 |
10 |
0.063
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.063
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.063
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.062
|
|
|
|
t helper 2 cell differentiation
|
GO:0045064 |
12 |
0.062
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.062
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.062
|
|
|
|
stem cell maintenance
|
GO:0019827 |
130 |
0.062
|
|
|
|
interleukin 12 biosynthetic process
|
GO:0042090 |
8 |
0.061
|
|
|
|
positive regulation of response to cytokine stimulus
|
GO:0060760 |
11 |
0.061
|
Mouse |
|
|
negative regulation of viral process
|
GO:0048525 |
23 |
0.060
|
|
|
|
necrotic cell death
|
GO:0070265 |
30 |
0.060
|
Mouse |
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.059
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.059
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.058
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.058
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
57 |
0.058
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.058
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.058
|
|
|
|
type i interferon biosynthetic process
|
GO:0045351 |
9 |
0.058
|
Mouse |
|
|
dendritic cell differentiation
|
GO:0097028 |
26 |
0.058
|
Mouse |
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.057
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.057
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
39 |
0.057
|
|
|
|
response to inorganic substance
|
GO:0010035 |
96 |
0.057
|
|
|
|
positive regulation of antigen processing and presentation
|
GO:0002579 |
10 |
0.057
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
169 |
0.057
|
|
|
|
keratinocyte differentiation
|
GO:0030216 |
48 |
0.056
|
Mouse |
|
|
somatic diversification of immune receptors
|
GO:0002200 |
53 |
0.056
|
|
|
|
cd8 positive alpha beta t cell proliferation
|
GO:0035740 |
1 |
0.056
|
|
|
|
regulation of necroptotic process
|
GO:0060544 |
10 |
0.056
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.054
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.054
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
59 |
0.054
|
|
|
|
regulation of tyrosine phosphorylation of stat1 protein
|
GO:0042510 |
2 |
0.054
|
|
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.054
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.054
|
|
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
45 |
0.054
|
|
|
|
regulation of lymphocyte apoptotic process
|
GO:0070228 |
41 |
0.053
|
|
|
|
adhesion of symbiont to host
|
GO:0044406 |
8 |
0.053
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.053
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.053
|
|
|
|
chromatin organization
|
GO:0006325 |
206 |
0.053
|
Mouse |
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.053
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.053
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.052
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
43 |
0.052
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.051
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.051
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.051
|
|
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
52 |
0.051
|
|
|
|
regulation of myd88 dependent toll like receptor signaling pathway
|
GO:0034124 |
2 |
0.051
|
|
|
|
positive regulation of defense response to bacterium
|
GO:1900426 |
1 |
0.051
|
|
|
|
positive regulation of notch signaling pathway
|
GO:0045747 |
18 |
0.051
|
|
|
|
t cell lineage commitment
|
GO:0002360 |
13 |
0.051
|
Mouse |
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.051
|
Mouse |
|
|
negative regulation of nik nf kappab signaling
|
GO:1901223 |
2 |
0.051
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
57 |
0.051
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
65 |
0.050
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.050
|
|
|
|
positive regulation of antibacterial peptide biosynthetic process
|
GO:0006963 |
1 |
0.050
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.049
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.049
|
|
|
|
response to muramyl dipeptide
|
GO:0032495 |
9 |
0.049
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
52 |
0.049
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.049
|
|
|
|
interleukin 4 production
|
GO:0032633 |
24 |
0.049
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
61 |
0.049
|
|
|
|
granulocyte chemotaxis
|
GO:0071621 |
39 |
0.049
|
|
|
|
somatic cell dna recombination
|
GO:0016444 |
51 |
0.049
|
|
|
|
regulation of immunoglobulin mediated immune response
|
GO:0002889 |
37 |
0.048
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.048
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.048
|
|
|
|
positive regulation of antimicrobial humoral response
|
GO:0002760 |
2 |
0.048
|
|
|
|
citrate metabolic process
|
GO:0006101 |
3 |
0.048
|
|
|
|
regulation of inflammatory response to antigenic stimulus
|
GO:0002861 |
21 |
0.047
|
|
|
|
chromatin modification
|
GO:0016568 |
187 |
0.047
|
Mouse |
|
|
response to copper ion
|
GO:0046688 |
3 |
0.047
|
|
|
|
negative regulation of intracellular protein transport
|
GO:0090317 |
27 |
0.047
|
|
|
|
regulation of t helper 1 type immune response
|
GO:0002825 |
17 |
0.047
|
|
|
|
interleukin 11 mediated signaling pathway
|
GO:0038154 |
2 |
0.046
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.046
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.046
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.046
|
|
|
|
negative regulation of t cell differentiation
|
GO:0045581 |
23 |
0.046
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.046
|
|
|
|
interleukin 12 production
|
GO:0032615 |
32 |
0.046
|
|
|
|
immunoglobulin production
|
GO:0002377 |
73 |
0.046
|
|
|
|
positive t cell selection
|
GO:0043368 |
23 |
0.046
|
Mouse |
|
|
protein targeting
|
GO:0006605 |
143 |
0.045
|
|
|
|
regulation of natural killer cell differentiation
|
GO:0032823 |
11 |
0.045
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.045
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.045
|
|
|
|
regulation of cytokine production involved in immune response
|
GO:0002718 |
26 |
0.045
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.045
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.045
|
|
|
|
polysaccharide metabolic process
|
GO:0005976 |
39 |
0.045
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
88 |
0.045
|
Human |
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.045
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.044
|
|
|
|
positive regulation of reactive oxygen species biosynthetic process
|
GO:1903428 |
2 |
0.044
|
|
|
|
cellular response to steroid hormone stimulus
|
GO:0071383 |
33 |
0.044
|
|
|
|
negative regulation of leukocyte proliferation
|
GO:0070664 |
46 |
0.044
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.044
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.044
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.044
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.044
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
60 |
0.044
|
|
|
|
regulation of mast cell differentiation
|
GO:0060375 |
3 |
0.044
|
|
|
|
modification of morphology or physiology of other organism involved in symbiotic interaction
|
GO:0051817 |
16 |
0.043
|
|
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
42 |
0.043
|
|
|
|
positive regulation of type i interferon mediated signaling pathway
|
GO:0060340 |
4 |
0.043
|
Mouse |
|
|
jak stat cascade involved in growth hormone signaling pathway
|
GO:0060397 |
4 |
0.043
|
|
|
|
mammary gland morphogenesis
|
GO:0060443 |
54 |
0.043
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.042
|
|
|
|
negative regulation of lymphocyte proliferation
|
GO:0050672 |
45 |
0.042
|
|
|
|
regulation of defense response to fungus
|
GO:1900150 |
1 |
0.042
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.042
|
|
|
|
cd4 positive alpha beta t cell lineage commitment
|
GO:0043373 |
6 |
0.042
|
Mouse |
|
|
t cell selection
|
GO:0045058 |
34 |
0.042
|
Mouse |
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.041
|
|
|
|
positive regulation of interleukin 1 beta production
|
GO:0032731 |
16 |
0.041
|
|
|
|
tolerance induction dependent upon immune response
|
GO:0002461 |
1 |
0.041
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
97 |
0.041
|
|
|
|
response to interleukin 1
|
GO:0070555 |
11 |
0.041
|
|
