Mus musculus

128 known processes

Irf7

interferon regulatory factor 7

Irf7 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
negative regulation of viral genome replication GO:0045071 10 1.000
viral process GO:0016032 41 0.995
negative regulation of viral process GO:0048525 23 0.992
interspecies interaction between organisms GO:0044419 83 0.991
Mouse
negative regulation of multi organism process GO:0043901 68 0.978
Mouse
defense response to other organism GO:0098542 197 0.977
Mouse
activation of innate immune response GO:0002218 56 0.977
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.976
Mouse
viral genome replication GO:0019079 17 0.975
defense response to virus GO:0051607 68 0.972
Mouse
innate immune response GO:0045087 157 0.967
pattern recognition receptor signaling pathway GO:0002221 47 0.967
viral life cycle GO:0019058 36 0.962
regulation of defense response GO:0031347 233 0.960
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.960
Mouse
t helper 2 cell cytokine production GO:0035745 4 0.955
cellular response to interferon alpha GO:0035457 4 0.943
immune effector process GO:0002252 321 0.924
defense response to bacterium GO:0042742 119 0.899
Mouse
regulation of innate immune response GO:0045088 91 0.887
regulation of toll like receptor signaling pathway GO:0034121 20 0.882
immune response regulating signaling pathway GO:0002764 125 0.857
toll like receptor 7 signaling pathway GO:0034154 4 0.854
regulation of multi organism process GO:0043900 111 0.824
Mouse
regulation of viral genome replication GO:0045069 13 0.812
regulation of t helper 2 cell cytokine production GO:2000551 3 0.805
rig i signaling pathway GO:0039529 4 0.783
protein modification by small protein conjugation or removal GO:0070647 207 0.763
positive regulation of defense response GO:0031349 124 0.759
toll like receptor signaling pathway GO:0002224 38 0.689
positive regulation of rig i signaling pathway GO:1900246 1 0.684
positive regulation of innate immune response GO:0045089 80 0.653
response to dsrna GO:0043331 30 0.611
Mouse
immune response activating signal transduction GO:0002757 116 0.607
positive regulation of viral genome replication GO:0045070 2 0.595
regulation of cytokine production GO:0001817 266 0.551
Human Mouse
cd4 positive alpha beta t cell cytokine production GO:0035743 4 0.524
positive regulation of toll like receptor 9 signaling pathway GO:0034165 2 0.482
cellular response to interferon beta GO:0035458 21 0.481
cellular response to type i interferon GO:0071357 10 0.463
interferon beta production GO:0032608 16 0.460
regulation of rig i signaling pathway GO:0039535 2 0.459
regulation of toll like receptor 9 signaling pathway GO:0034163 3 0.457
cellular nitrogen compound catabolic process GO:0044270 280 0.449
protein modification by small protein conjugation GO:0032446 187 0.438
response to interferon beta GO:0035456 22 0.434
response to type i interferon GO:0034340 12 0.423
isg15 protein conjugation GO:0032020 4 0.417
cytoplasmic pattern recognition receptor signaling pathway in response to virus GO:0039528 4 0.377
innate immune response activating signal transduction GO:0002758 50 0.376
macromolecule catabolic process GO:0009057 281 0.362
t helper 17 cell lineage commitment GO:0072540 4 0.338
Mouse
positive regulation of cytokine production GO:0001819 174 0.331
Human Mouse
regulation of myd88 independent toll like receptor signaling pathway GO:0034127 1 0.328
intracellular protein transport GO:0006886 204 0.322
cd8 positive alpha beta t cell proliferation GO:0035740 1 0.313
Mouse
positive regulation of immune effector process GO:0002699 107 0.306
activation of immune response GO:0002253 138 0.296
type i interferon signaling pathway GO:0060337 10 0.295
intracellular transport of virus GO:0075733 1 0.292
regulation of defense response to virus by host GO:0050691 8 0.281
Mouse
nucleotide metabolic process GO:0009117 332 0.278
negative regulation of protein metabolic process GO:0051248 282 0.261
Mouse
cellular response to cytokine stimulus GO:0071345 189 0.259
leukocyte mediated immunity GO:0002443 174 0.257
regulation of leukocyte mediated immunity GO:0002703 104 0.253
cellular macromolecule catabolic process GO:0044265 206 0.248
homeostasis of number of cells GO:0048872 210 0.244
negative regulation of cellular protein metabolic process GO:0032269 247 0.236
regulation of protein transport GO:0051223 163 0.230
negative regulation of cell proliferation GO:0008285 296 0.228
Mouse
alpha beta t cell differentiation involved in immune response GO:0002293 30 0.226
Mouse
protein ubiquitination GO:0016567 171 0.224
adaptive immune response GO:0002250 155 0.208
positive regulation of interferon alpha production GO:0032727 4 0.203
Human Mouse
nucleobase containing small molecule metabolic process GO:0055086 352 0.195
myeloid cell differentiation GO:0030099 233 0.191
Mouse
cd4 positive alpha beta t cell activation GO:0035710 45 0.189
Mouse
regulation of type 2 immune response GO:0002828 18 0.189
leukocyte differentiation GO:0002521 342 0.188
Mouse
regulation of cytokine production involved in immune response GO:0002718 26 0.186
alpha beta t cell differentiation GO:0046632 69 0.185
Mouse
positive regulation of t helper 2 cell cytokine production GO:2000553 3 0.184
rna catabolic process GO:0006401 29 0.181
regulation of adaptive immune response GO:0002819 90 0.173
Human
lymphocyte differentiation GO:0030098 242 0.171
Mouse
negative regulation of immune system process GO:0002683 209 0.169
Mouse
alpha beta t cell activation GO:0046631 91 0.168
Mouse
regulation of defense response to virus GO:0050688 18 0.163
Mouse
cytokine biosynthetic process GO:0042089 68 0.161
modification dependent macromolecule catabolic process GO:0043632 133 0.159
cellular protein catabolic process GO:0044257 155 0.158
t cell differentiation GO:0030217 174 0.155
Mouse
negative regulation of cytokine production GO:0001818 84 0.150
Mouse
regulation of homeostatic process GO:0032844 182 0.146
cytokine production involved in immune response GO:0002367 34 0.144
positive regulation of production of molecular mediator of immune response GO:0002702 45 0.143
positive regulation of type i interferon mediated signaling pathway GO:0060340 4 0.143
positive regulation of t cell cytokine production GO:0002726 5 0.142
myeloid cell homeostasis GO:0002262 114 0.138
viral gene expression GO:0019080 3 0.138
cellular response to interferon gamma GO:0071346 25 0.136
Mouse
heterocycle catabolic process GO:0046700 280 0.135
regulation of type i interferon mediated signaling pathway GO:0060338 7 0.134
organelle assembly GO:0070925 177 0.130
toll like receptor 9 signaling pathway GO:0034162 6 0.129
positive regulation of adaptive immune response GO:0002821 61 0.129
negative regulation of defense response GO:0031348 77 0.124
Mouse
positive regulation of t cell mediated immunity GO:0002711 24 0.116
regulation of response to biotic stimulus GO:0002831 38 0.115
Mouse
regulation of protein localization GO:0032880 231 0.113
cytokine mediated signaling pathway GO:0019221 115 0.111
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.109
protein catabolic process GO:0030163 221 0.108
modification dependent protein catabolic process GO:0019941 133 0.107
negative regulation of molecular function GO:0044092 258 0.107
organonitrogen compound biosynthetic process GO:1901566 192 0.106
negative regulation of defense response to virus GO:0050687 6 0.106
Mouse
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.104
glycosyl compound metabolic process GO:1901657 246 0.104
nucleoside phosphate biosynthetic process GO:1901293 79 0.102
negative regulation of defense response to virus by host GO:0050689 1 0.100
Mouse
regulation of cd8 positive alpha beta t cell proliferation GO:2000564 1 0.100
Mouse
production of molecular mediator of immune response GO:0002440 103 0.100
response to organic cyclic compound GO:0014070 198 0.098
Mouse
regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway GO:0039531 2 0.098
purine containing compound metabolic process GO:0072521 311 0.097
purine containing compound catabolic process GO:0072523 213 0.097
production of small rna involved in gene silencing by rna GO:0070918 6 0.096
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.095
cellular response to lipopolysaccharide GO:0071222 77 0.094
Mouse
carbohydrate metabolic process GO:0005975 230 0.094
ras protein signal transduction GO:0007265 77 0.090
organophosphate catabolic process GO:0046434 232 0.090
regulation of interferon beta production GO:0032648 13 0.089
Mouse
mda 5 signaling pathway GO:0039530 1 0.089
regulation of defense response to bacterium GO:1900424 3 0.088
erythrocyte differentiation GO:0030218 88 0.087
t cell activation GO:0042110 289 0.087
Mouse
nucleoside phosphate metabolic process GO:0006753 338 0.085
hair follicle cell proliferation GO:0071335 3 0.083
regulation of interferon gamma production GO:0032649 57 0.082
Mouse
t cell lineage commitment GO:0002360 13 0.081
Mouse
myeloid dendritic cell differentiation GO:0043011 16 0.081
Mouse
dendritic cell differentiation GO:0097028 26 0.080
Mouse
negative regulation of viral transcription GO:0032897 3 0.079
cellular response to biotic stimulus GO:0071216 92 0.076
Mouse
regulation of protein ubiquitination GO:0031396 52 0.076
nucleoside triphosphate catabolic process GO:0009143 205 0.075
t cell cytokine production GO:0002369 10 0.075
protein acylation GO:0043543 64 0.074
Mouse
negative regulation of rig i signaling pathway GO:0039536 2 0.071
rna interference GO:0016246 2 0.070
positive regulation of cell activation GO:0050867 158 0.070
negative regulation of interferon beta production GO:0032688 3 0.069
Mouse
gland development GO:0048732 330 0.069
Mouse
organophosphate biosynthetic process GO:0090407 122 0.069
negative regulation of protein transport GO:0051224 46 0.068
regulation of cellular component biogenesis GO:0044087 181 0.067
Mouse
regulation of secretion GO:0051046 274 0.067
purine nucleotide biosynthetic process GO:0006164 65 0.065
protein import GO:0017038 101 0.065
positive regulation of leukocyte mediated immunity GO:0002705 70 0.065
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.065
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.064
schwann cell proliferation GO:0014010 2 0.064
positive regulation of type i interferon production GO:0032481 14 0.064
Human Mouse
positive regulation of lymphocyte activation GO:0051251 140 0.062
positive regulation of interleukin 12 production GO:0032735 21 0.061
Mouse
negative regulation of innate immune response GO:0045824 17 0.061
stem cell development GO:0048864 219 0.060
interleukin 12 production GO:0032615 32 0.060
Mouse
positive regulation of myeloid cell differentiation GO:0045639 43 0.060
histone acetylation GO:0016573 41 0.060
Mouse
pre mirna processing GO:0031054 3 0.060
positive regulation of cytokine biosynthetic process GO:0042108 40 0.059
Mouse
protein polyubiquitination GO:0000209 33 0.057
ear development GO:0043583 200 0.057
lymphocyte mediated immunity GO:0002449 139 0.057
protein oligomerization GO:0051259 67 0.057
regulation of t cell mediated immunity GO:0002709 34 0.056
regulation of lymphocyte mediated immunity GO:0002706 84 0.054
glycoprotein metabolic process GO:0009100 116 0.053
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.053
olfactory bulb interneuron differentiation GO:0021889 12 0.052
posttranscriptional regulation of gene expression GO:0010608 155 0.052
germ cell development GO:0007281 185 0.052
regulation of cd8 positive alpha beta t cell activation GO:2001185 3 0.051
Mouse
transmission of nerve impulse GO:0019226 76 0.051
positive regulation of cytokine production involved in immune response GO:0002720 19 0.051
myoblast differentiation involved in skeletal muscle regeneration GO:0014835 3 0.051
posttranscriptional gene silencing by rna GO:0035194 10 0.050
muscle cell differentiation GO:0042692 261 0.050
cellular response to lipid GO:0071396 145 0.049
Mouse
posttranscriptional gene silencing GO:0016441 10 0.049
organic cyclic compound catabolic process GO:1901361 295 0.048
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.047
muscle tissue development GO:0060537 308 0.046
t cell mediated immunity GO:0002456 50 0.045
macromolecule glycosylation GO:0043413 55 0.043
i kappab kinase nf kappab signaling GO:0007249 85 0.043
stem cell differentiation GO:0048863 268 0.043
gene silencing by mirna GO:0035195 10 0.043
leukocyte chemotaxis GO:0030595 69 0.043
negative regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway GO:0039532 2 0.043
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.043
nucleocytoplasmic transport GO:0006913 139 0.042
schwann cell differentiation GO:0014037 26 0.042
regulation of mapk cascade GO:0043408 248 0.042
response to phenylpropanoid GO:0080184 22 0.042
regulation of cell migration GO:0030334 219 0.042
dna metabolic process GO:0006259 303 0.042
microtubule cytoskeleton organization GO:0000226 157 0.042
regulation of leukocyte proliferation GO:0070663 121 0.041
Mouse
positive regulation of multi organism process GO:0043902 26 0.041
citrate metabolic process GO:0006101 3 0.041
regulation of neutrophil mediated killing of gram negative bacterium GO:0070951 1 0.040
chromatin organization GO:0006325 206 0.040
Mouse
ribonucleoside catabolic process GO:0042454 206 0.040
stem cell maintenance GO:0019827 130 0.040
negative regulation of immune effector process GO:0002698 55 0.039
Mouse
spleen development GO:0048536 39 0.039
purine containing compound biosynthetic process GO:0072522 70 0.039
type i interferon production GO:0032606 29 0.039
ribonucleotide metabolic process GO:0009259 291 0.039
lipid storage GO:0019915 36 0.039
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.039
Mouse
regulation of cellular ketone metabolic process GO:0010565 66 0.038
positive regulation of viral process GO:0048524 5 0.038
neuronal action potential GO:0019228 54 0.038
regulation of cell motility GO:2000145 236 0.038
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.038
positive regulation of leukocyte differentiation GO:1902107 86 0.037
regulation of binding GO:0051098 111 0.037
Mouse
positive regulation of cellular component biogenesis GO:0044089 94 0.037
Mouse
negative regulation of response to biotic stimulus GO:0002832 10 0.037
Mouse
muscle cell development GO:0055001 133 0.037
myelination in peripheral nervous system GO:0022011 19 0.037
negative regulation of viral release from host cell GO:1902187 6 0.036
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.036
small gtpase mediated signal transduction GO:0007264 97 0.036
cell activation involved in immune response GO:0002263 126 0.036
Mouse
cellular response to dna damage stimulus GO:0006974 207 0.036
response to stilbenoid GO:0035634 22 0.036
muscle cell apoptotic process GO:0010657 18 0.035
protein localization to organelle GO:0033365 185 0.035
nucleotide biosynthetic process GO:0009165 78 0.035
lipid localization GO:0010876 126 0.035
regulation of macrophage fusion GO:0034239 3 0.035
regulation of cytoplasmic transport GO:1903649 112 0.034
regulation of organ morphogenesis GO:2000027 144 0.034
regulation of viral transcription GO:0046782 3 0.034
viral transcription GO:0019083 3 0.034
purine ribonucleotide metabolic process GO:0009150 290 0.033
protein targeting GO:0006605 143 0.033
type 2 immune response GO:0042092 23 0.033
leukocyte activation involved in immune response GO:0002366 126 0.033
Mouse
regulation of myeloid cell differentiation GO:0045637 96 0.033
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 25 0.033
mapk cascade GO:0000165 281 0.033
regulation of kinase activity GO:0043549 249 0.033
hair follicle morphogenesis GO:0031069 29 0.033
histone modification GO:0016570 159 0.032
Mouse
ribose phosphate metabolic process GO:0019693 291 0.032
nuclear transport GO:0051169 139 0.032
response to molecule of bacterial origin GO:0002237 143 0.032
Mouse
immunoglobulin mediated immune response GO:0016064 69 0.032
regulation of myd88 dependent toll like receptor signaling pathway GO:0034124 2 0.031
negative regulation of lymphocyte activation GO:0051250 91 0.031
Mouse
female gamete generation GO:0007292 74 0.031
positive regulation of apoptotic process GO:0043065 217 0.031
mammary gland epithelium development GO:0061180 65 0.031
Mouse
regulation of cell activation GO:0050865 289 0.031
Mouse
dsrna fragmentation GO:0031050 6 0.031
regulation of hormone levels GO:0010817 211 0.030
purine nucleotide metabolic process GO:0006163 302 0.030
purine ribonucleotide catabolic process GO:0009154 208 0.030
negative regulation of nf kappab transcription factor activity GO:0032088 15 0.030
regulation of dna templated transcription initiation GO:2000142 7 0.030
Mouse
protein import into nucleus GO:0006606 95 0.030
lipopolysaccharide mediated signaling pathway GO:0031663 25 0.029
Mouse
nucleoside phosphate catabolic process GO:1901292 222 0.029
maintenance of location GO:0051235 89 0.029
positive regulation of t cell activation GO:0050870 101 0.029
interleukin 5 secretion GO:0072603 2 0.029
cytokine metabolic process GO:0042107 71 0.029
regulation of hydrolase activity GO:0051336 246 0.029
negative regulation of cellular component organization GO:0051129 194 0.028
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.028
epithelial cell proliferation GO:0050673 174 0.028
Mouse
pallium development GO:0021543 120 0.028
protein localization to nucleus GO:0034504 121 0.028
axon ensheathment GO:0008366 76 0.028
regulation of establishment of protein localization GO:0070201 181 0.027
purine ribonucleoside catabolic process GO:0046130 205 0.027
regulation of tumor necrosis factor production GO:0032680 49 0.027
limb morphogenesis GO:0035108 149 0.027
regulation of membrane potential GO:0042391 192 0.027
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.027
myeloid dendritic cell activation GO:0001773 25 0.027
Mouse
epithelial tube morphogenesis GO:0060562 303 0.027
negative regulation of t cell differentiation GO:0045581 23 0.027
Mouse
alpha beta t cell activation involved in immune response GO:0002287 31 0.027
Mouse
positive regulation of transferase activity GO:0051347 167 0.027
positive regulation of programmed cell death GO:0043068 218 0.027
epidermis morphogenesis GO:0048730 33 0.026
regulation of schwann cell proliferation GO:0010624 2 0.026
positive regulation of kinase activity GO:0033674 155 0.026
telencephalon development GO:0021537 186 0.026
regulation of nucleocytoplasmic transport GO:0046822 73 0.026
divalent metal ion transport GO:0070838 172 0.026
negative regulation of toll like receptor signaling pathway GO:0034122 14 0.026
Mouse
regulation of proteolysis GO:0030162 164 0.026
peptidyl amino acid modification GO:0018193 336 0.025
Mouse
regulation of protein binding GO:0043393 60 0.025
immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 43 0.025
regulation of interleukin 10 secretion GO:2001179 4 0.025
regulation of interferon alpha production GO:0032647 5 0.025
Human Mouse
nuclear import GO:0051170 95 0.025
reactive oxygen species metabolic process GO:0072593 84 0.025
action potential GO:0001508 78 0.025
cellular amino acid metabolic process GO:0006520 103 0.025
neutrophil migration GO:1990266 37 0.024
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.024
cellular response to molecule of bacterial origin GO:0071219 83 0.024
Mouse
cytoplasmic transport GO:0016482 234 0.024
regulation of cell killing GO:0031341 40 0.024
lymphocyte activation involved in immune response GO:0002285 93 0.023
Mouse
positive regulation of type 2 immune response GO:0002830 9 0.023
covalent chromatin modification GO:0016569 163 0.023
Mouse
morphogenesis of a branching structure GO:0001763 203 0.023
negative regulation of phosphorylation GO:0042326 166 0.023
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.023
glycosylation GO:0070085 62 0.022
spermatogenesis GO:0007283 284 0.022
negative regulation of protein modification process GO:0031400 163 0.022
atp metabolic process GO:0046034 75 0.022
natural killer cell proliferation GO:0001787 3 0.022
regulation of organelle organization GO:0033043 289 0.022
blood vessel morphogenesis GO:0048514 285 0.022
cellular amine metabolic process GO:0044106 44 0.022
protein glycosylation GO:0006486 55 0.022
regulation of interleukin 12 production GO:0032655 30 0.022
Mouse
cell killing GO:0001906 67 0.022
ribonucleoside triphosphate metabolic process GO:0009199 220 0.022
negative regulation of interleukin 6 production GO:0032715 17 0.022
positive regulation of protein kinase activity GO:0045860 144 0.022
negative regulation of protein ubiquitination GO:0031397 19 0.022
interleukin 4 mediated signaling pathway GO:0035771 2 0.021
aromatic compound catabolic process GO:0019439 286 0.021
positive regulation of ion transport GO:0043270 65 0.021
cellular response to dsrna GO:0071359 12 0.021
ubiquitin dependent protein catabolic process GO:0006511 129 0.021
hatching GO:0035188 4 0.021
pyrimidine containing compound catabolic process GO:0072529 3 0.021
endocytosis GO:0006897 168 0.021
Mouse
negative regulation of nervous system development GO:0051961 156 0.021
antigen processing and presentation GO:0019882 47 0.021
interferon gamma production GO:0032609 67 0.021
Mouse
regulation of lymphocyte activation GO:0051249 240 0.021
Mouse
positive regulation of protein modification process GO:0031401 299 0.020
regulation of transferase activity GO:0051338 263 0.020
positive regulation of neutrophil mediated killing of symbiont cell GO:0070961 1 0.020
natural killer cell mediated cytotoxicity GO:0042267 29 0.020
t cell activation involved in immune response GO:0002286 43 0.020
Mouse
purine nucleoside catabolic process GO:0006152 205 0.020
purine ribonucleoside metabolic process GO:0046128 241 0.020
nucleoside catabolic process GO:0009164 206 0.020
mesenchymal cell development GO:0014031 93 0.020
negative regulation of kinase activity GO:0033673 81 0.020
cellular ketone metabolic process GO:0042180 84 0.020
regulation of protein secretion GO:0050708 82 0.020
response to growth factor GO:0070848 198 0.019
killing of cells in other organism involved in symbiotic interaction GO:0051883 13 0.019
gene silencing GO:0016458 38 0.019
regulation of production of molecular mediator of immune response GO:0002700 65 0.019
regulation of nlrp3 inflammasome complex assembly GO:1900225 4 0.019
negative regulation of protein phosphorylation GO:0001933 126 0.019
cell type specific apoptotic process GO:0097285 268 0.019
positive regulation of inflammatory response GO:0050729 47 0.019
cellular homeostasis GO:0019725 240 0.019
multicellular organism growth GO:0035264 161 0.019
positive regulation of mapk cascade GO:0043410 170 0.019
defense response to protozoan GO:0042832 25 0.019
Mouse
interleukin 13 secretion GO:0072611 2 0.019
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.019
cation homeostasis GO:0055080 212 0.019
antigen processing and presentation of peptide antigen GO:0048002 29 0.019
response to interferon alpha GO:0035455 7 0.018
circadian temperature homeostasis GO:0060086 2 0.018
positive regulation of viral entry into host cell GO:0046598 3 0.018
regulation of gliogenesis GO:0014013 50 0.018
regulation of intracellular protein transport GO:0033157 82 0.018
divalent inorganic cation transport GO:0072511 178 0.018
cellular response to organic cyclic compound GO:0071407 87 0.018
response to exogenous dsrna GO:0043330 22 0.018
Mouse
sequestering of calcium ion GO:0051208 18 0.018
t cell differentiation in thymus GO:0033077 77 0.018
negative regulation of secretion by cell GO:1903531 54 0.018
cellular response to growth factor stimulus GO:0071363 197 0.018
taurine metabolic process GO:0019530 4 0.018
negative regulation of cell development GO:0010721 169 0.018
cd4 positive alpha beta t cell lineage commitment GO:0043373 6 0.018
Mouse
forebrain development GO:0030900 302 0.018
epithelial cell development GO:0002064 159 0.018
purine nucleotide catabolic process GO:0006195 211 0.018
odontogenesis of dentin containing tooth GO:0042475 66 0.018
mechanoreceptor differentiation GO:0042490 67 0.018
regulation of odontogenesis GO:0042481 18 0.017
cd4 positive or cd8 positive alpha beta t cell lineage commitment GO:0043369 8 0.017
Mouse
regulation of secretion by cell GO:1903530 249 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.017
mitotic cell cycle GO:0000278 195 0.017
regulation of cellular catabolic process GO:0031329 242 0.017
positive regulation of chemotaxis GO:0050921 38 0.017
purine nucleoside triphosphate catabolic process GO:0009146 203 0.017
positive regulation of protein phosphorylation GO:0001934 242 0.017
signal transduction involved in dna damage checkpoint GO:0072422 3 0.017
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.017
regulation of type i interferon production GO:0032479 22 0.017
Human Mouse
glycoprotein biosynthetic process GO:0009101 89 0.017
negative regulation of syncytium formation by plasma membrane fusion GO:0034242 5 0.017
organism emergence from protective structure GO:0071684 4 0.016
oligodendrocyte differentiation GO:0048709 53 0.016
purine nucleoside monophosphate metabolic process GO:0009126 81 0.016
regulation of natural killer cell mediated cytotoxicity GO:0042269 19 0.016
carbohydrate homeostasis GO:0033500 128 0.016
t helper cell differentiation GO:0042093 28 0.016
Mouse
negative regulation of binding GO:0051100 39 0.016
regulation of cytokine biosynthetic process GO:0042035 59 0.016
Mouse
regulation of protein catabolic process GO:0042176 108 0.016
cellular protein complex assembly GO:0043623 116 0.016
nucleoside triphosphate metabolic process GO:0009141 230 0.016
lipoprotein biosynthetic process GO:0042158 33 0.016
ribonucleoside triphosphate catabolic process GO:0009203 199 0.016
interaction with host GO:0051701 22 0.016
microtubule based process GO:0007017 236 0.015
protein secretion GO:0009306 111 0.015
negative regulation of cell activation GO:0050866 111 0.015
Mouse
regulation of interleukin 6 production GO:0032675 55 0.015
regulation of actin nucleation GO:0051125 4 0.015
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.015
digestive system development GO:0055123 200 0.015
hair follicle development GO:0001942 85 0.015
peptidyl lysine modification GO:0018205 77 0.015
Mouse
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.015
neutrophil mediated killing of fungus GO:0070947 3 0.015
autophagy GO:0006914 45 0.015
regulation of cellular amine metabolic process GO:0033238 20 0.015
glial cell differentiation GO:0010001 131 0.015
angiogenesis GO:0001525 201 0.015
glucose homeostasis GO:0042593 128 0.015
regulation of dna binding GO:0051101 39 0.015
Mouse
extrinsic apoptotic signaling pathway GO:0097191 126 0.015
regulation of protein complex assembly GO:0043254 83 0.015
Mouse
skeletal system development GO:0001501 356 0.015
movement in host environment GO:0052126 15 0.015
tumor necrosis factor production GO:0032640 50 0.015
regulation of mitotic cell cycle GO:0007346 126 0.014
positive regulation of transcription initiation from rna polymerase ii promoter GO:0060261 5 0.014
Mouse
peptidyl tyrosine phosphorylation GO:0018108 143 0.014
striated muscle cell development GO:0055002 125 0.014
extracellular structure organization GO:0043062 148 0.014
transcription initiation from rna polymerase ii promoter GO:0006367 8 0.014
Mouse
regulation of glial cell differentiation GO:0045685 41 0.014
single organism nuclear import GO:1902593 95 0.014
steroid metabolic process GO:0008202 119 0.014
regulation of cellular amino acid metabolic process GO:0006521 5 0.014
oogenesis GO:0048477 56 0.014
cell adhesion GO:0007155 329 0.014
positive regulation of nf kappab transcription factor activity GO:0051092 30 0.014
molting cycle GO:0042303 90 0.014
negative regulation of interleukin 5 secretion GO:2000663 1 0.014
positive regulation of fever generation by positive regulation of prostaglandin secretion GO:0071812 2 0.014
cellular component assembly involved in morphogenesis GO:0010927 139 0.014
forebrain generation of neurons GO:0021872 63 0.014
organonitrogen compound catabolic process GO:1901565 264 0.013
regulation of protein kinase activity GO:0045859 232 0.013
apoptotic signaling pathway GO:0097190 306 0.013
positive regulation of interleukin 12 biosynthetic process GO:0045084 6 0.013
Mouse
multicellular organismal signaling GO:0035637 91 0.013
myoblast differentiation GO:0045445 52 0.013
positive regulation of protein catabolic process GO:0045732 60 0.013

Irf7 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
glucose metabolism disease DOID:4194 0 0.030
type 1 diabetes mellitus DOID:9744 0 0.030
acquired metabolic disease DOID:0060158 0 0.030
disease of metabolism DOID:0014667 0 0.030
carbohydrate metabolism disease DOID:0050013 0 0.030
diabetes mellitus DOID:9351 0 0.030
disease of anatomical entity DOID:7 0 0.019
musculoskeletal system disease DOID:17 0 0.019
bone remodeling disease DOID:0080005 0 0.014
connective tissue disease DOID:65 0 0.014
osteopetrosis DOID:13533 0 0.014
osteosclerosis DOID:4254 0 0.014
bone disease DOID:0080001 0 0.014