Mus musculus

14 known processes

Irf9

interferon regulatory factor 9

(Aliases: Irf-9,p48,Isgf3g)

Irf9 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cellular response to type i interferon GO:0071357 10 0.999
Mouse
type i interferon signaling pathway GO:0060337 10 0.997
Mouse
response to type i interferon GO:0034340 12 0.997
Mouse
viral process GO:0016032 41 0.995
natural killer cell differentiation GO:0001779 21 0.989
innate immune response GO:0045087 157 0.988
Mouse
viral life cycle GO:0019058 36 0.981
citrate metabolic process GO:0006101 3 0.978
interspecies interaction between organisms GO:0044419 83 0.975
Mouse
regulation of nlrp3 inflammasome complex assembly GO:1900225 4 0.970
regulation of mast cell differentiation GO:0060375 3 0.970
cd4 positive or cd8 positive alpha beta t cell lineage commitment GO:0043369 8 0.957
Mouse
natural killer cell proliferation GO:0001787 3 0.951
defense response to virus GO:0051607 68 0.951
Mouse
positive regulation of innate immune response GO:0045089 80 0.949
Mouse
cellular response to cytokine stimulus GO:0071345 189 0.948
Mouse
response to interferon gamma GO:0034341 34 0.937
Mouse
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.934
Mouse
regulation of cytokine production GO:0001817 266 0.930
Mouse
lipopolysaccharide mediated signaling pathway GO:0031663 25 0.926
Mouse
cd4 positive alpha beta t cell lineage commitment GO:0043373 6 0.926
Mouse
t helper cell differentiation GO:0042093 28 0.924
Mouse
t cell lineage commitment GO:0002360 13 0.924
Mouse
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 28 0.919
Mouse
type i interferon production GO:0032606 29 0.913
cellular response to lipid GO:0071396 145 0.908
Mouse
defense response to other organism GO:0098542 197 0.907
Mouse
activation of innate immune response GO:0002218 56 0.904
Mouse
jak stat cascade involved in growth hormone signaling pathway GO:0060397 4 0.899
progesterone metabolic process GO:0042448 4 0.896
positive regulation of gamma delta t cell differentiation GO:0045588 6 0.890
cytokine production GO:0001816 319 0.887
t helper 1 cell lineage commitment GO:0002296 2 0.883
cytokine biosynthetic process GO:0042089 68 0.880
protein modification by small protein conjugation or removal GO:0070647 207 0.879
creatinine metabolic process GO:0046449 3 0.879
cellular response to interferon beta GO:0035458 21 0.879
regulation of natural killer cell differentiation GO:0032823 11 0.877
positive regulation of type i interferon mediated signaling pathway GO:0060340 4 0.877
Mouse
negative regulation of macrophage fusion GO:0034240 1 0.875
mast cell proliferation GO:0070662 4 0.875
response to dsrna GO:0043331 30 0.873
Mouse
cellular response to interferon gamma GO:0071346 25 0.866
Mouse
pattern recognition receptor signaling pathway GO:0002221 47 0.862
Mouse
valine metabolic process GO:0006573 4 0.862
positive regulation of natural killer cell mediated immunity GO:0002717 16 0.859
response to granulocyte macrophage colony stimulating factor GO:0097012 3 0.853
alpha beta t cell differentiation involved in immune response GO:0002293 30 0.851
Mouse
negative regulation of nlrp3 inflammasome complex assembly GO:1900226 2 0.851
negative regulation of cell proliferation GO:0008285 296 0.842
Mouse
erythrocyte differentiation GO:0030218 88 0.840
positive regulation of rig i signaling pathway GO:1900246 1 0.835
regulation of defense response GO:0031347 233 0.825
Mouse
creatine metabolic process GO:0006600 4 0.822
cellular response to lipopolysaccharide GO:0071222 77 0.815
Mouse
negative regulation of immune system process GO:0002683 209 0.815
Mouse
negative regulation of viral genome replication GO:0045071 10 0.813
positive regulation of cytokine biosynthetic process GO:0042108 40 0.813
Mouse
regulation of b cell differentiation GO:0045577 23 0.811
rig i signaling pathway GO:0039529 4 0.803
carbohydrate catabolic process GO:0016052 32 0.799
regulation of mast cell proliferation GO:0070666 4 0.797
taurine metabolic process GO:0019530 4 0.796
cd4 positive alpha beta t cell activation GO:0035710 45 0.794
Mouse
response to interleukin 15 GO:0070672 3 0.793
cellular response to granulocyte macrophage colony stimulating factor stimulus GO:0097011 3 0.789
regulation of macrophage fusion GO:0034239 3 0.788
oxaloacetate metabolic process GO:0006107 5 0.785
response to interferon alpha GO:0035455 7 0.781
allantoin metabolic process GO:0000255 3 0.772
movement in environment of other organism involved in symbiotic interaction GO:0052192 15 0.754
interleukin 4 mediated signaling pathway GO:0035771 2 0.753
lymphocyte mediated immunity GO:0002449 139 0.740
Mouse
positive regulation of cytokine production GO:0001819 174 0.734
Mouse
pyruvate metabolic process GO:0006090 28 0.729
negative regulation of viral release from host cell GO:1902187 6 0.722
positive regulation of mast cell differentiation GO:0060376 1 0.719
regulation of defense response to virus by host GO:0050691 8 0.717
Mouse
alpha beta t cell activation involved in immune response GO:0002287 31 0.715
Mouse
response to molecule of bacterial origin GO:0002237 143 0.714
Mouse
regulation of toll like receptor signaling pathway GO:0034121 20 0.709
Mouse
regulation of natural killer cell activation GO:0032814 22 0.709
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.704
Mouse
positive t cell selection GO:0043368 23 0.692
Mouse
positive regulation of viral genome replication GO:0045070 2 0.691
dna recombination GO:0006310 92 0.686
negative regulation of multi organism process GO:0043901 68 0.683
Mouse
t helper cell lineage commitment GO:0002295 6 0.681
Mouse
regulation of cell activation GO:0050865 289 0.681
Mouse
protein modification by small protein conjugation GO:0032446 187 0.680
cytokine mediated signaling pathway GO:0019221 115 0.668
Mouse
myeloid cell homeostasis GO:0002262 114 0.664
lymphocyte activation involved in immune response GO:0002285 93 0.662
Mouse
regulation of cytokine biosynthetic process GO:0042035 59 0.661
Mouse
glycolytic process GO:0006096 20 0.661
immune response activating signal transduction GO:0002757 116 0.659
Mouse
regulation of viral genome replication GO:0045069 13 0.655
eye photoreceptor cell differentiation GO:0001754 41 0.653
cellular response to biotic stimulus GO:0071216 92 0.653
Mouse
macrophage fusion GO:0034238 3 0.653
regulation of homeostatic process GO:0032844 182 0.645
regulation of innate immune response GO:0045088 91 0.643
Mouse
regulation of mast cell apoptotic process GO:0033025 5 0.642
regulation of interleukin 2 biosynthetic process GO:0045076 13 0.632
alpha beta t cell differentiation GO:0046632 69 0.631
Mouse
negative regulation of glycolytic process GO:0045820 4 0.628
gamma delta t cell differentiation GO:0042492 11 0.627
regulation of endopeptidase activity GO:0052548 89 0.623
development of secondary male sexual characteristics GO:0046544 3 0.621
mucosal associated lymphoid tissue development GO:0048537 12 0.617
adaptive immune response GO:0002250 155 0.611
Mouse
myeloid leukocyte differentiation GO:0002573 119 0.610
Mouse
mast cell apoptotic process GO:0033024 5 0.608
regulation of natural killer cell mediated cytotoxicity GO:0042269 19 0.602
response to interleukin 2 GO:0070669 2 0.589
activation of cysteine type endopeptidase activity GO:0097202 27 0.588
defense response to protozoan GO:0042832 25 0.585
Mouse
regulation of isotype switching to ige isotypes GO:0048293 7 0.578
b cell activation involved in immune response GO:0002312 50 0.575
regulation of type i interferon mediated signaling pathway GO:0060338 7 0.573
Mouse
immune response regulating signaling pathway GO:0002764 125 0.573
Mouse
regulation of erythrocyte differentiation GO:0045646 23 0.572
negative regulation of syncytium formation by plasma membrane fusion GO:0034242 5 0.569
isoleucine metabolic process GO:0006549 4 0.566
t cell homeostasis GO:0043029 35 0.565
viral genome replication GO:0019079 17 0.564
negative regulation of viral process GO:0048525 23 0.563
alpha amino acid metabolic process GO:1901605 59 0.563
response to interferon beta GO:0035456 22 0.561
negative regulation of myeloid cell differentiation GO:0045638 38 0.560
regulation of production of molecular mediator of immune response GO:0002700 65 0.554
regulation of natural killer cell mediated immunity GO:0002715 19 0.554
natural killer cell mediated cytotoxicity GO:0042267 29 0.553
regulation of type 2 immune response GO:0002828 18 0.549
cellular modified amino acid metabolic process GO:0006575 63 0.543
regulation of viral release from host cell GO:1902186 6 0.531
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.523
response to interleukin 4 GO:0070670 23 0.522
isotype switching to ige isotypes GO:0048289 7 0.522
t cell differentiation involved in immune response GO:0002292 30 0.518
Mouse
positive regulation of viral entry into host cell GO:0046598 3 0.515
peyer s patch development GO:0048541 12 0.514
negative regulation of erythrocyte differentiation GO:0045647 5 0.512
negative regulation of cellular carbohydrate metabolic process GO:0010677 19 0.512
leukocyte differentiation GO:0002521 342 0.508
Mouse
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.504
natural killer cell activation GO:0030101 44 0.499
myeloid cell differentiation GO:0030099 233 0.499
Mouse
response to organic cyclic compound GO:0014070 198 0.494
Mouse
positive regulation of immune effector process GO:0002699 107 0.489
regulation of leukocyte mediated immunity GO:0002703 104 0.486
regulation of t cell activation GO:0050863 170 0.483
Mouse
positive regulation of interleukin 2 biosynthetic process GO:0045086 8 0.483
regulation of cellular catabolic process GO:0031329 242 0.479
negative regulation of mast cell apoptotic process GO:0033026 4 0.479
lipid homeostasis GO:0055088 63 0.479
gliogenesis GO:0042063 141 0.476
carbohydrate homeostasis GO:0033500 128 0.474
positive regulation of actin nucleation GO:0051127 3 0.473
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.473
Mouse
immune effector process GO:0002252 321 0.468
Mouse
regulation of peptidase activity GO:0052547 96 0.464
movement in host environment GO:0052126 15 0.463
sulfur compound metabolic process GO:0006790 100 0.461
regulation of lymphocyte activation GO:0051249 240 0.457
Mouse
positive regulation of cysteine type endopeptidase activity GO:2001056 39 0.455
negative regulation of cell development GO:0010721 169 0.453
regulation of t cell proliferation GO:0042129 92 0.451
Mouse
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.449
Mouse
female sex differentiation GO:0046660 84 0.448
cellular response to interleukin 4 GO:0071353 21 0.446
positive regulation of type i interferon production GO:0032481 14 0.446
Mouse
regulation of myd88 independent toll like receptor signaling pathway GO:0034127 1 0.443
Mouse
homeostasis of number of cells GO:0048872 210 0.443
positive regulation of mitotic cell cycle GO:0045931 41 0.442
gland development GO:0048732 330 0.439
Mouse
regulation of lymphocyte mediated immunity GO:0002706 84 0.434
zymogen activation GO:0031638 41 0.433
generation of precursor metabolites and energy GO:0006091 103 0.432
somatic cell dna recombination GO:0016444 51 0.428
regulation of rig i signaling pathway GO:0039535 2 0.424
innate immune response activating signal transduction GO:0002758 50 0.423
Mouse
toll like receptor signaling pathway GO:0002224 38 0.420
Mouse
interferon gamma mediated signaling pathway GO:0060333 5 0.416
Mouse
cellular amino acid metabolic process GO:0006520 103 0.410
regulation of natural killer cell proliferation GO:0032817 2 0.405
positive regulation of production of molecular mediator of immune response GO:0002702 45 0.400
interleukin 2 biosynthetic process GO:0042094 15 0.399
regulation of glycolytic process GO:0006110 10 0.398
negative regulation of cellular protein metabolic process GO:0032269 247 0.398
positive regulation of peptidase activity GO:0010952 49 0.398
positive regulation of interferon alpha production GO:0032727 4 0.397
Mouse
cell fate commitment GO:0045165 210 0.393
Mouse
regulation of multi organism process GO:0043900 111 0.390
Mouse
negative regulation of toll like receptor signaling pathway GO:0034122 14 0.390
Mouse
entry into cell of other organism involved in symbiotic interaction GO:0051806 15 0.382
syncytium formation by plasma membrane fusion GO:0000768 42 0.382
cytoplasmic pattern recognition receptor signaling pathway in response to virus GO:0039528 4 0.378
photoreceptor cell differentiation GO:0046530 52 0.377
positive regulation of proteolysis GO:0045862 85 0.375
somatic diversification of immunoglobulins involved in immune response GO:0002208 36 0.371
hormone mediated signaling pathway GO:0009755 23 0.366
negative regulation of cellular component organization GO:0051129 194 0.363
epithelial cell differentiation involved in prostate gland development GO:0060742 13 0.361
immunoglobulin production GO:0002377 73 0.360
positive regulation of cell killing GO:0031343 33 0.359
somatic diversification of immune receptors GO:0002200 53 0.358
negative regulation of type 2 immune response GO:0002829 8 0.357
alpha beta t cell activation GO:0046631 91 0.352
Mouse
regulation of inflammatory response GO:0050727 147 0.349
regulation of lymphocyte differentiation GO:0045619 107 0.349
Mouse
dicarboxylic acid metabolic process GO:0043648 18 0.346
t helper 1 type immune response GO:0042088 25 0.344
luteinization GO:0001553 8 0.344
t cell selection GO:0045058 34 0.342
Mouse
regulation of gamma delta t cell activation GO:0046643 9 0.341
cellular response to interferon alpha GO:0035457 4 0.340
positive regulation of isotype switching to ige isotypes GO:0048295 4 0.339
regulation of leukocyte differentiation GO:1902105 159 0.339
Mouse
lactation GO:0007595 25 0.338
somatic recombination of immunoglobulin gene segments GO:0016447 42 0.338
phospholipid homeostasis GO:0055091 6 0.336
regulation of leukocyte mediated cytotoxicity GO:0001910 38 0.333
regulation of syncytium formation by plasma membrane fusion GO:0060142 23 0.332
regulation of hydrolase activity GO:0051336 246 0.327
regulation of body fluid levels GO:0050878 162 0.326
viral gene expression GO:0019080 3 0.324
positive regulation of myeloid cell differentiation GO:0045639 43 0.323
regulation of adaptive immune response GO:0002819 90 0.322
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.320
t cell differentiation in thymus GO:0033077 77 0.318
interleukin 2 production GO:0032623 33 0.317
somatic recombination of immunoglobulin genes involved in immune response GO:0002204 36 0.317
alpha beta t cell lineage commitment GO:0002363 7 0.316
Mouse
nucleotide metabolic process GO:0009117 332 0.316
natural killer cell mediated immunity GO:0002228 29 0.314
cellular amide metabolic process GO:0043603 58 0.309
gamma delta t cell activation GO:0046629 13 0.307
glial cell differentiation GO:0010001 131 0.305
entry into host cell GO:0030260 15 0.304
cellular response to molecule of bacterial origin GO:0071219 83 0.303
Mouse
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.302
stem cell maintenance GO:0019827 130 0.300
negative regulation of defense response to virus by host GO:0050689 1 0.299
Mouse
inflammatory response GO:0006954 244 0.298
regulation of actin nucleation GO:0051125 4 0.297
regulation of neuron migration GO:2001222 22 0.294
positive regulation of activated t cell proliferation GO:0042104 8 0.291
temperature homeostasis GO:0001659 26 0.290
regulation of cysteine type endopeptidase activity GO:2000116 65 0.290
regulation of defense response to virus GO:0050688 18 0.290
Mouse
isotype switching GO:0045190 36 0.288
prostate gland epithelium morphogenesis GO:0060740 31 0.285
positive regulation of natural killer cell activation GO:0032816 15 0.284
t cell activation GO:0042110 289 0.284
Mouse
positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 0.283
regulation of interferon alpha production GO:0032647 5 0.282
Mouse
cell activation involved in immune response GO:0002263 126 0.281
Mouse
peptidyl tyrosine phosphorylation GO:0018108 143 0.279
negative regulation of nervous system development GO:0051961 156 0.279
positive regulation of myeloid leukocyte differentiation GO:0002763 26 0.277
tricarboxylic acid metabolic process GO:0072350 5 0.276
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.276
positive regulation of adaptive immune response GO:0002821 61 0.270
mammary gland epithelium development GO:0061180 65 0.267
Mouse
lymphocyte homeostasis GO:0002260 64 0.265
protein ubiquitination GO:0016567 171 0.265
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.264
organic cyclic compound catabolic process GO:1901361 295 0.264
cellular macromolecule catabolic process GO:0044265 206 0.262
mammary gland epithelial cell proliferation GO:0033598 24 0.260
astrocyte differentiation GO:0048708 43 0.258
monocarboxylic acid metabolic process GO:0032787 191 0.254
negative regulation of neuron migration GO:2001223 6 0.253
regulation of cell motility GO:2000145 236 0.253
regulation of dna recombination GO:0000018 34 0.253
response to lipopolysaccharide GO:0032496 128 0.248
Mouse
ovulation cycle GO:0042698 59 0.247
stem cell development GO:0048864 219 0.247
negative regulation of myeloid cell apoptotic process GO:0033033 11 0.241
fatty acid metabolic process GO:0006631 121 0.240
positive regulation of programmed cell death GO:0043068 218 0.237
cellular ketone metabolic process GO:0042180 84 0.237
positive regulation of lymphocyte activation GO:0051251 140 0.234
syncytium formation GO:0006949 43 0.233
protein processing GO:0016485 163 0.233
regulation of hormone levels GO:0010817 211 0.232
positive regulation of endopeptidase activity GO:0010950 43 0.231
neuron migration GO:0001764 122 0.231
hormone metabolic process GO:0042445 86 0.231
glucose homeostasis GO:0042593 128 0.229
sensory organ morphogenesis GO:0090596 242 0.227
lipid storage GO:0019915 36 0.225
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.224
cellular response to growth hormone stimulus GO:0071378 7 0.224
carbohydrate metabolic process GO:0005975 230 0.221
negative regulation of cell migration GO:0030336 59 0.221
prostate gland development GO:0030850 48 0.220
steroid metabolic process GO:0008202 119 0.219
leukocyte homeostasis GO:0001776 79 0.217
negative regulation of protein metabolic process GO:0051248 282 0.216
Mouse
dna metabolic process GO:0006259 303 0.216
regulation of interleukin 2 production GO:0032663 28 0.214
b cell differentiation GO:0030183 78 0.212
stem cell differentiation GO:0048863 268 0.211
regulation of leukocyte apoptotic process GO:2000106 56 0.210
notch signaling pathway GO:0007219 71 0.210
t helper 1 cell differentiation GO:0045063 13 0.209
mammary gland morphogenesis GO:0060443 54 0.209
positive regulation of leukocyte proliferation GO:0070665 73 0.208
regulation of reactive oxygen species metabolic process GO:2000377 40 0.208
negative regulation of carbohydrate metabolic process GO:0045912 19 0.208
interaction with host GO:0051701 22 0.206
regulation of myeloid leukocyte differentiation GO:0002761 58 0.206
regulation of cell migration GO:0030334 219 0.206
t helper 17 cell lineage commitment GO:0072540 4 0.204
Mouse
lymphocyte differentiation GO:0030098 242 0.202
Mouse
response to growth factor GO:0070848 198 0.202
rhythmic process GO:0048511 174 0.201
positive regulation of immunoglobulin production GO:0002639 28 0.201
t cell differentiation GO:0030217 174 0.200
Mouse
regulation of gamma delta t cell differentiation GO:0045586 9 0.199
regulation of response to wounding GO:1903034 189 0.198
regulation of carbohydrate catabolic process GO:0043470 12 0.196
regulation of leukocyte proliferation GO:0070663 121 0.196
Mouse
positive regulation of natural killer cell differentiation GO:0032825 7 0.193
positive regulation of mast cell proliferation GO:0070668 3 0.193
regulation of response to biotic stimulus GO:0002831 38 0.192
Mouse
cell killing GO:0001906 67 0.191
b cell activation GO:0042113 161 0.191
positive regulation of b cell mediated immunity GO:0002714 26 0.189
regulation of b cell mediated immunity GO:0002712 37 0.189
negative regulation of homeostatic process GO:0032845 71 0.189
positive regulation of defense response GO:0031349 124 0.188
Mouse
leukocyte apoptotic process GO:0071887 71 0.188
positive regulation of cell cycle GO:0045787 92 0.188
somatic diversification of immunoglobulins GO:0016445 43 0.186
radial glial cell differentiation GO:0060019 6 0.184
cellular response to peptide GO:1901653 92 0.184
regulation of interferon beta production GO:0032648 13 0.184
Mouse
positive regulation of t cell activation GO:0050870 101 0.182
regulation of carbohydrate metabolic process GO:0006109 75 0.180
regulation of b cell activation GO:0050864 81 0.177
regulation of myeloid cell differentiation GO:0045637 96 0.177
regulation of isotype switching GO:0045191 22 0.176
maintenance of location GO:0051235 89 0.176
male sex differentiation GO:0046661 109 0.175
mast cell differentiation GO:0060374 5 0.175
nucleoside triphosphate catabolic process GO:0009143 205 0.175
aromatic compound catabolic process GO:0019439 286 0.173
regulation of cell cycle GO:0051726 281 0.172
positive regulation of response to wounding GO:1903036 66 0.170
positive regulation of cell death GO:0010942 224 0.170
regulation of proteolysis GO:0030162 164 0.169
response to protozoan GO:0001562 28 0.169
Mouse
positive regulation of apoptotic process GO:0043065 217 0.168
positive regulation of growth GO:0045927 104 0.167
response to peptide hormone GO:0043434 127 0.166
positive regulation of interleukin 2 production GO:0032743 19 0.166
positive regulation of cellular component biogenesis GO:0044089 94 0.166
Mouse
cellular carbohydrate metabolic process GO:0044262 119 0.164
cell adhesion GO:0007155 329 0.164
multicellular organism growth GO:0035264 161 0.163
protein maturation GO:0051604 176 0.162
leukocyte mediated cytotoxicity GO:0001909 62 0.162
positive regulation of lymphocyte differentiation GO:0045621 61 0.161
ribonucleoside triphosphate metabolic process GO:0009199 220 0.159
regulation of steroid metabolic process GO:0019218 39 0.159
nucleobase containing small molecule metabolic process GO:0055086 352 0.158
type 2 immune response GO:0042092 23 0.158
regulation of immunoglobulin production GO:0002637 42 0.157
production of molecular mediator of immune response GO:0002440 103 0.157
nucleoside metabolic process GO:0009116 246 0.154
entry into host GO:0044409 15 0.154
cellular lactam metabolic process GO:0072338 3 0.152
production of small rna involved in gene silencing by rna GO:0070918 6 0.151
epithelial cell proliferation GO:0050673 174 0.151
Mouse
negative regulation of viral transcription GO:0032897 3 0.151
cellular carbohydrate catabolic process GO:0044275 15 0.150
positive regulation of isotype switching GO:0045830 15 0.148
body fluid secretion GO:0007589 53 0.148
immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 43 0.148
jak stat cascade GO:0007259 42 0.147
regulation of viral entry into host cell GO:0046596 12 0.147
cell type specific apoptotic process GO:0097285 268 0.146
development of primary female sexual characteristics GO:0046545 73 0.143
mast cell homeostasis GO:0033023 5 0.143
nucleoside catabolic process GO:0009164 206 0.141
cd8 positive alpha beta t cell proliferation GO:0035740 1 0.141
Mouse
positive regulation of leukocyte mediated immunity GO:0002705 70 0.139
urogenital system development GO:0001655 261 0.139
macromolecule catabolic process GO:0009057 281 0.137
feeding behavior GO:0007631 62 0.135
positive regulation of notch signaling pathway GO:0045747 18 0.135
ubiquitin dependent protein catabolic process GO:0006511 129 0.134
nlrp3 inflammasome complex assembly GO:0044546 5 0.133
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.133
cellular lipid metabolic process GO:0044255 323 0.131
mda 5 signaling pathway GO:0039530 1 0.129
cellular nitrogen compound catabolic process GO:0044270 280 0.127
regulation of viral transcription GO:0046782 3 0.126
development of secondary female sexual characteristics GO:0046543 8 0.125
pre mirna processing GO:0031054 3 0.124
mitotic cell cycle GO:0000278 195 0.123
negative regulation of viral entry into host cell GO:0046597 10 0.121
positive regulation of b cell differentiation GO:0045579 13 0.120
succinate metabolic process GO:0006105 4 0.119
ribonucleoside triphosphate catabolic process GO:0009203 199 0.117
positive regulation of hydrolase activity GO:0051345 148 0.114
regulation of lipid metabolic process GO:0019216 118 0.113
positive regulation of inflammatory response GO:0050729 47 0.113
regulation of notch signaling pathway GO:0008593 35 0.113
lipid localization GO:0010876 126 0.113
protein polyubiquitination GO:0000209 33 0.112
ribonucleotide metabolic process GO:0009259 291 0.111
purine nucleoside triphosphate catabolic process GO:0009146 203 0.110
histone modification GO:0016570 159 0.106
Mouse
positive regulation of t cell differentiation GO:0045582 52 0.106
activation of immune response GO:0002253 138 0.106
Mouse
positive regulation of cell activation GO:0050867 158 0.105
branched chain amino acid metabolic process GO:0009081 6 0.104
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 27 0.103
prostate gland morphogenesis GO:0060512 32 0.103
glycosyl compound catabolic process GO:1901658 206 0.103
purine nucleotide metabolic process GO:0006163 302 0.101
nucleocytoplasmic transport GO:0006913 139 0.100
regulation of type i interferon production GO:0032479 22 0.098
Mouse
viral release from host cell GO:0019076 6 0.098
purine nucleoside catabolic process GO:0006152 205 0.098
leukocyte mediated immunity GO:0002443 174 0.097
Mouse
immunoglobulin mediated immune response GO:0016064 69 0.097
Mouse
signal transduction involved in dna damage checkpoint GO:0072422 3 0.096
entry into other organism involved in symbiotic interaction GO:0051828 15 0.096
response to organonitrogen compound GO:0010243 246 0.094
positive regulation of dna recombination GO:0045911 17 0.094
gene silencing by mirna GO:0035195 10 0.094
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.094
regulation of intracellular transport GO:0032386 159 0.094
positive regulation of leukocyte differentiation GO:1902107 86 0.094
cellular response to organonitrogen compound GO:0071417 145 0.093
ribonucleoside metabolic process GO:0009119 245 0.093
negative regulation of cytokine production GO:0001818 84 0.092
Mouse
positive regulation of lymphocyte proliferation GO:0050671 70 0.092
autophagy GO:0006914 45 0.091
positive regulation of b cell activation GO:0050871 49 0.091
2 oxoglutarate metabolic process GO:0006103 7 0.089
eating behavior GO:0042755 15 0.088
regulation of mitotic cell cycle GO:0007346 126 0.088
regulation of protein transport GO:0051223 163 0.088
viral transcription GO:0019083 3 0.087
regulation of cellular carbohydrate catabolic process GO:0043471 12 0.086
glycosyl compound metabolic process GO:1901657 246 0.085
negative regulation of protein modification by small protein conjugation or removal GO:1903321 20 0.084
purine containing compound catabolic process GO:0072523 213 0.084
response to peptide GO:1901652 136 0.083
interferon alpha production GO:0032607 7 0.083
Mouse
regulation of cell adhesion GO:0030155 154 0.082
protein oligomerization GO:0051259 67 0.081
negative regulation of cell motility GO:2000146 61 0.080
purine ribonucleotide catabolic process GO:0009154 208 0.080
gtp metabolic process GO:0046039 144 0.078
spleen development GO:0048536 39 0.078
regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway GO:0039531 2 0.078
female gonad development GO:0008585 71 0.077
isg15 protein conjugation GO:0032020 4 0.077
regulation of cellular component biogenesis GO:0044087 181 0.076
Mouse
nucleoside phosphate metabolic process GO:0006753 338 0.076
defense response to gram negative bacterium GO:0050829 28 0.076
purine nucleoside monophosphate metabolic process GO:0009126 81 0.076
ribonucleoside catabolic process GO:0042454 206 0.075
purine nucleotide catabolic process GO:0006195 211 0.075
intracellular protein transport GO:0006886 204 0.075
regulation of myeloid cell apoptotic process GO:0033032 19 0.074
negative regulation of defense response GO:0031348 77 0.074
Mouse
multi multicellular organism process GO:0044706 109 0.073
nucleoside phosphate catabolic process GO:1901292 222 0.073
regulation of interleukin 6 production GO:0032675 55 0.072
peptidyl tyrosine modification GO:0018212 145 0.070
ribose phosphate metabolic process GO:0019693 291 0.069
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.069
organonitrogen compound catabolic process GO:1901565 264 0.068
anion homeostasis GO:0055081 16 0.067
myd88 independent toll like receptor signaling pathway GO:0002756 3 0.066
Mouse
defense response to gram positive bacterium GO:0050830 50 0.066
defense response to bacterium GO:0042742 119 0.065
Mouse
development of secondary sexual characteristics GO:0045136 11 0.064
purine ribonucleotide metabolic process GO:0009150 290 0.064
regulation of immunoglobulin mediated immune response GO:0002889 37 0.063
purine nucleoside metabolic process GO:0042278 241 0.063
modification dependent protein catabolic process GO:0019941 133 0.063
viral entry into host cell GO:0046718 15 0.062
nucleoside triphosphate metabolic process GO:0009141 230 0.062
regulation of activated t cell proliferation GO:0046006 16 0.062
positive regulation of viral process GO:0048524 5 0.062
negative regulation of protein ubiquitination GO:0031397 19 0.062
histone h3 acetylation GO:0043966 14 0.061
Mouse
growth hormone receptor signaling pathway GO:0060396 7 0.061
positive regulation of immunoglobulin mediated immune response GO:0002891 26 0.061
purine ribonucleoside catabolic process GO:0046130 205 0.060
hair follicle cell proliferation GO:0071335 3 0.060

Irf9 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org