|
|
positive regulation of lipid kinase activity
|
GO:0090218 |
11 |
0.972
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.971
|
Human |
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.958
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.951
|
Human Mouse Rat Fly |
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.941
|
Human |
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
40 |
0.862
|
|
|
|
regulation of insulin receptor signaling pathway
|
GO:0046626 |
21 |
0.850
|
Rat |
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.842
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.835
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.831
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.824
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.819
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.799
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.796
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.796
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.771
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.762
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.762
|
|
|
|
heart morphogenesis
|
GO:0003007 |
178 |
0.757
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.728
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.721
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.707
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.701
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.691
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.689
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.686
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
78 |
0.667
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.662
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.642
|
|
|
|
cell cell adhesion via plasma membrane adhesion molecules
|
GO:0098742 |
40 |
0.632
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.627
|
|
|
|
female gamete generation
|
GO:0007292 |
74 |
0.619
|
Fly |
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.618
|
Human |
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.617
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
42 |
0.606
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.603
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.598
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.591
|
|
|
|
glucose metabolic process
|
GO:0006006 |
92 |
0.589
|
Human |
|
|
response to monosaccharide
|
GO:0034284 |
67 |
0.582
|
Mouse |
|
|
negative regulation of synapse assembly
|
GO:0051964 |
3 |
0.574
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.569
|
|
|
|
stem cell proliferation
|
GO:0072089 |
117 |
0.558
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.547
|
Human Mouse Rat |
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.529
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.526
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.526
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.525
|
|
|
|
response to testosterone
|
GO:0033574 |
3 |
0.521
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.513
|
|
|
|
polysaccharide metabolic process
|
GO:0005976 |
39 |
0.506
|
Human |
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.505
|
|
|
|
olfactory learning
|
GO:0008355 |
2 |
0.503
|
Fly |
|
|
establishment of protein localization to organelle
|
GO:0072594 |
118 |
0.500
|
|
|
|
regulation of lipid kinase activity
|
GO:0043550 |
14 |
0.493
|
|
|
|
regulation of phosphatidylinositol 3 kinase activity
|
GO:0043551 |
14 |
0.492
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
163 |
0.491
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.488
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
106 |
0.487
|
Human |
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.483
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.482
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.480
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.478
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.478
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.476
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.475
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.469
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.464
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.464
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.464
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.462
|
Fly |
|
|
cognition
|
GO:0050890 |
149 |
0.462
|
Fly |
|
|
regulation of lipid metabolic process
|
GO:0019216 |
118 |
0.461
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.460
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.459
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.451
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.450
|
Mouse |
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.445
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.442
|
|
|
|
organ growth
|
GO:0035265 |
117 |
0.440
|
Fly |
|
|
protein processing
|
GO:0016485 |
163 |
0.435
|
|
|
|
glycerolipid biosynthetic process
|
GO:0045017 |
50 |
0.435
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.429
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.424
|
|
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.421
|
|
|
|
axial mesoderm morphogenesis
|
GO:0048319 |
5 |
0.421
|
|
|
|
neural precursor cell proliferation
|
GO:0061351 |
121 |
0.420
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.417
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.409
|
|
|
|
polarity specification of proximal distal axis
|
GO:0010085 |
2 |
0.403
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.401
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.398
|
|
|
|
glucose transport
|
GO:0015758 |
56 |
0.393
|
Human |
|
|
positive regulation of phosphatidylinositol 3 kinase activity
|
GO:0043552 |
11 |
0.390
|
|
|
|
positive regulation of growth
|
GO:0045927 |
104 |
0.387
|
Fly |
|
|
muscle system process
|
GO:0003012 |
141 |
0.383
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.383
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.381
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.379
|
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
143 |
0.378
|
|
|
|
response to amino acid
|
GO:0043200 |
37 |
0.376
|
|
|
|
syncytium formation
|
GO:0006949 |
43 |
0.376
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.376
|
Human |
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
94 |
0.370
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.364
|
Fly |
|
|
germ cell development
|
GO:0007281 |
185 |
0.359
|
Fly |
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.357
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.354
|
|
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.354
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.353
|
Fly |
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.350
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.349
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.348
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.347
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.345
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.343
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
52 |
0.338
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.336
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.334
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.332
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.329
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.322
|
Mouse |
|
|
germ line stem cell division
|
GO:0042078 |
2 |
0.322
|
Fly |
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.318
|
Mouse |
|
|
glucose import
|
GO:0046323 |
32 |
0.317
|
Human |
|
|
connective tissue development
|
GO:0061448 |
179 |
0.316
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.314
|
|
|
|
protein import into nucleus
|
GO:0006606 |
95 |
0.314
|
|
|
|
protein import
|
GO:0017038 |
101 |
0.314
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.305
|
Fly |
|
|
nuclear import
|
GO:0051170 |
95 |
0.303
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.297
|
|
|
|
hindbrain development
|
GO:0030902 |
128 |
0.295
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
82 |
0.295
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.290
|
|
|
|
appendage development
|
GO:0048736 |
166 |
0.289
|
|
|
|
skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration
|
GO:0014834 |
3 |
0.288
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.287
|
Fly |
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.287
|
|
|
|
peptide secretion
|
GO:0002790 |
114 |
0.279
|
Human Mouse Rat |
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.279
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.278
|
|
|
|
regulation of cell projection assembly
|
GO:0060491 |
38 |
0.276
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
88 |
0.276
|
Human Mouse Rat |
|
|
glucan metabolic process
|
GO:0044042 |
32 |
0.274
|
Human |
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.273
|
|
|
|
positive regulation of glial cell proliferation
|
GO:0060252 |
4 |
0.269
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.265
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.265
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
86 |
0.265
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.264
|
|
|
|
positive regulation of glycogen metabolic process
|
GO:0070875 |
8 |
0.258
|
Human |
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.257
|
Mouse |
|
|
skeletal system development
|
GO:0001501 |
356 |
0.254
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.253
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.253
|
|
|
|
regulation of fatty acid metabolic process
|
GO:0019217 |
28 |
0.252
|
Human |
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.249
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.247
|
|
|
|
regulation of stem cell proliferation
|
GO:0072091 |
78 |
0.246
|
|
|
|
maintenance of cell number
|
GO:0098727 |
3 |
0.246
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.245
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.245
|
|
|
|
positive regulation of neuron projection development
|
GO:0010976 |
79 |
0.244
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.244
|
Human Mouse Rat |
|
|
axial mesoderm formation
|
GO:0048320 |
3 |
0.242
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
74 |
0.240
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.240
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.238
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.237
|
|
|
|
neural tube formation
|
GO:0001841 |
108 |
0.237
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.236
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.234
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
49 |
0.233
|
|
|
|
associative learning
|
GO:0008306 |
61 |
0.233
|
Fly |
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.232
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.230
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
79 |
0.228
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
92 |
0.227
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.226
|
|
|
|
negative regulation of neuron projection development
|
GO:0010977 |
50 |
0.225
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.225
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.224
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.223
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.221
|
|
|
|
carbohydrate transport
|
GO:0008643 |
62 |
0.221
|
Human |
|
|
muscle fiber development
|
GO:0048747 |
76 |
0.218
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.217
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.216
|
|
|
|
positive regulation of lipid catabolic process
|
GO:0050996 |
6 |
0.216
|
Human |
|
|
regulation of neuron projection development
|
GO:0010975 |
169 |
0.215
|
|
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.215
|
Human |
|
|
cell cell adhesion
|
GO:0098609 |
41 |
0.213
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.212
|
|
|
|
synapse organization
|
GO:0050808 |
125 |
0.212
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.212
|
Mouse |
|
|
energy reserve metabolic process
|
GO:0006112 |
39 |
0.212
|
Human |
|
|
insulin receptor signaling pathway
|
GO:0008286 |
49 |
0.211
|
Human Mouse Rat Fly |
|
|
kidney development
|
GO:0001822 |
213 |
0.210
|
|
|
|
regulation of peptide secretion
|
GO:0002791 |
77 |
0.210
|
Human Mouse Rat |
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.209
|
|
|
|
regulation of fatty acid beta oxidation
|
GO:0031998 |
1 |
0.208
|
Human |
|
|
neural tube development
|
GO:0021915 |
160 |
0.206
|
|
|
|
cartilage development
|
GO:0051216 |
140 |
0.204
|
|
|
|
translation
|
GO:0006412 |
93 |
0.202
|
|
|
|
endothelial cell migration
|
GO:0043542 |
44 |
0.201
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.201
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.200
|
|
|
|
muscle contraction
|
GO:0006936 |
101 |
0.200
|
|
|
|
monosaccharide transport
|
GO:0015749 |
58 |
0.200
|
Human |
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.199
|
Fly |
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.198
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.198
|
Fly |
|
|
blood circulation
|
GO:0008015 |
195 |
0.198
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
207 |
0.197
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.195
|
|
|
|
epithelium migration
|
GO:0090132 |
63 |
0.193
|
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.190
|
|
|
|
exocrine system development
|
GO:0035272 |
45 |
0.188
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.187
|
|
|
|
regulation of rna polymerase ii transcriptional preinitiation complex assembly
|
GO:0045898 |
2 |
0.186
|
|
|
|
regulation of lipid catabolic process
|
GO:0050994 |
15 |
0.186
|
Human |
|
|
regulation of blood pressure
|
GO:0008217 |
93 |
0.184
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.182
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.181
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.180
|
Mouse |
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.180
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.179
|
|
|
|
nuclear transport
|
GO:0051169 |
139 |
0.178
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.178
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.177
|
|
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.176
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
64 |
0.175
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.174
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.173
|
Human Mouse Rat |
|
|
asymmetric stem cell division
|
GO:0098722 |
3 |
0.173
|
Fly |
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.172
|
|
|
|
positive regulation of insulin secretion
|
GO:0032024 |
26 |
0.172
|
Mouse |
|
|
heart contraction
|
GO:0060047 |
93 |
0.171
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
119 |
0.169
|
Human |
|
|
ossification
|
GO:0001503 |
216 |
0.168
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.165
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
62 |
0.164
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.164
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.161
|
|
|
|
commissural neuron axon guidance
|
GO:0071679 |
8 |
0.160
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.159
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.159
|
Human |
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.158
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.155
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.154
|
|
|
|
glycerophospholipid biosynthetic process
|
GO:0046474 |
32 |
0.152
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
101 |
0.152
|
|
|
|
response to insulin
|
GO:0032868 |
100 |
0.151
|
|
|
|
female sex differentiation
|
GO:0046660 |
84 |
0.151
|
|
|
|
body morphogenesis
|
GO:0010171 |
45 |
0.151
|
|
|
|
regulation of embryonic development
|
GO:0045995 |
71 |
0.150
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.150
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.150
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.149
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
71 |
0.149
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
119 |
0.149
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.148
|
|
|
|
syncytiotrophoblast cell differentiation involved in labyrinthine layer development
|
GO:0060715 |
2 |
0.147
|
|
|
|
cell junction organization
|
GO:0034330 |
77 |
0.146
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.146
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
46 |
0.145
|
|
|
|
asymmetric neuroblast division
|
GO:0055059 |
1 |
0.143
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.143
|
|
|
|
male germ line stem cell asymmetric division
|
GO:0048133 |
2 |
0.142
|
Fly |
|
|
learning
|
GO:0007612 |
98 |
0.142
|
Fly |
|
|
developmental maturation
|
GO:0021700 |
193 |
0.142
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.139
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.139
|
Fly |
|
|
regulation of peptidyl serine phosphorylation
|
GO:0033135 |
39 |
0.138
|
|
|
|
regulation of protein processing
|
GO:0070613 |
96 |
0.138
|
|
|
|
regulation of glucan biosynthetic process
|
GO:0010962 |
7 |
0.138
|
Human |
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.137
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
62 |
0.137
|
|
|
|
developmental cell growth
|
GO:0048588 |
84 |
0.137
|
Fly |
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.136
|
Mouse |
|
|
labyrinthine layer development
|
GO:0060711 |
49 |
0.136
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.135
|
Mouse |
|
|
synapse assembly
|
GO:0007416 |
56 |
0.132
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.132
|
|
|
|
hippocampus development
|
GO:0021766 |
52 |
0.132
|
|
|
|
insulin like growth factor receptor signaling pathway
|
GO:0048009 |
21 |
0.132
|
Human |
|
|
gland development
|
GO:0048732 |
330 |
0.131
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.130
|
Mouse |
|
|
cerebellum morphogenesis
|
GO:0021587 |
42 |
0.129
|
|
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.129
|
|
|
|
ureteric bud development
|
GO:0001657 |
94 |
0.129
|
|
|
|
homophilic cell adhesion via plasma membrane adhesion molecules
|
GO:0007156 |
18 |
0.129
|
|
|
|
phosphatidylinositol biosynthetic process
|
GO:0006661 |
15 |
0.129
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
49 |
0.128
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.128
|
|
|
|
adult behavior
|
GO:0030534 |
135 |
0.127
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
56 |
0.127
|
|
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
60 |
0.126
|
|
|
|
plasma membrane long chain fatty acid transport
|
GO:0015911 |
1 |
0.126
|
|
|
|
regulation of peptide hormone secretion
|
GO:0090276 |
75 |
0.125
|
Human Mouse Rat |
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.124
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
61 |
0.124
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
95 |
0.123
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
82 |
0.123
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.122
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.122
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.122
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
60 |
0.121
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.121
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.120
|
|
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.119
|
Fly |
|
|
negative regulation of prostatic bud formation
|
GO:0060686 |
4 |
0.118
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.117
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
81 |
0.117
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
127 |
0.116
|
Fly |
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
82 |
0.116
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.116
|
|
|
|
response to metal ion
|
GO:0010038 |
47 |
0.116
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
96 |
0.116
|
|
|
|
neuron migration
|
GO:0001764 |
122 |
0.116
|
|
|
|
cerebral cortex development
|
GO:0021987 |
86 |
0.115
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.115
|
|
|
|
cartilage development involved in endochondral bone morphogenesis
|
GO:0060351 |
24 |
0.114
|
|
|
|
regulation of feeding behavior
|
GO:0060259 |
3 |
0.113
|
|
|
|
defecation
|
GO:0030421 |
1 |
0.113
|
|
|
|
regulation of glucose transport
|
GO:0010827 |
32 |
0.112
|
Human |
|
|
regulation of generation of precursor metabolites and energy
|
GO:0043467 |
38 |
0.112
|
Human |
|
|
ear development
|
GO:0043583 |
200 |
0.112
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.112
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
87 |
0.111
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.111
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.111
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
73 |
0.111
|
|
|
|
regulation of gliogenesis
|
GO:0014013 |
50 |
0.111
|
|
|
|
wnt signaling pathway planar cell polarity pathway
|
GO:0060071 |
27 |
0.110
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.110
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
65 |
0.110
|
|
|
|
ovulation
|
GO:0030728 |
15 |
0.110
|
|
|
|
hexose metabolic process
|
GO:0019318 |
98 |
0.109
|
Human |
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.109
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.109
|
Mouse |
|
|
germline stem cell asymmetric division
|
GO:0098728 |
2 |
0.109
|
Fly |
|
|
glycogen metabolic process
|
GO:0005977 |
32 |
0.109
|
Human |
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.109
|
Human Mouse Rat |
|
|
muscle cell proliferation
|
GO:0033002 |
52 |
0.108
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.107
|
|
|
|
cellular response to acid chemical
|
GO:0071229 |
68 |
0.106
|
|
|
|
adult locomotory behavior
|
GO:0008344 |
91 |
0.106
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.106
|
|
|
|
cellular response to amino acid stimulus
|
GO:0071230 |
29 |
0.106
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
123 |
0.105
|
|
|
|
pallium development
|
GO:0021543 |
120 |
0.105
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.105
|
|
|
|
central nervous system neuron differentiation
|
GO:0021953 |
162 |
0.105
|
|
|
|
ephrin receptor signaling pathway
|
GO:0048013 |
20 |
0.105
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.104
|
Mouse |
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.104
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.103
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.103
|
|
|
|
activation of janus kinase activity
|
GO:0042976 |
2 |
0.102
|
|
|
|
oligodendrocyte differentiation
|
GO:0048709 |
53 |
0.101
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.101
|
|
|
|
heart process
|
GO:0003015 |
94 |
0.101
|
|
|
|
notochord cell development
|
GO:0060035 |
1 |
0.100
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.100
|
Mouse |
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.100
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
68 |
0.100
|
|
|
|
oogenesis
|
GO:0048477 |
56 |
0.099
|
Fly |
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.098
|
|
|
|
negative regulation of neuron differentiation
|
GO:0045665 |
101 |
0.097
|
|
|
|
response to radiation
|
GO:0009314 |
165 |
0.097
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.096
|
|
|
|
axis elongation involved in somitogenesis
|
GO:0090245 |
4 |
0.096
|
|
|
|
platelet activation
|
GO:0030168 |
40 |
0.096
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.096
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
119 |
0.095
|
|
|
|
cellular glucan metabolic process
|
GO:0006073 |
32 |
0.095
|
Human |
|
|
regulation of glial cell differentiation
|
GO:0045685 |
41 |
0.095
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.094
|
|
|
|
primary neural tube formation
|
GO:0014020 |
95 |
0.094
|
|
|
|
gastrulation
|
GO:0007369 |
116 |
0.094
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
139 |
0.094
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.093
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.093
|
Mouse |
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.092
|
|
|
|
neuron projection regeneration
|
GO:0031102 |
14 |
0.092
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.092
|
|
|
|
regulation of endothelial cell migration
|
GO:0010594 |
22 |
0.092
|
|
|
|
regulation of neuron projection regeneration
|
GO:0070570 |
7 |
0.092
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.092
|
|
|
|
progesterone secretion
|
GO:0042701 |
1 |
0.092
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.092
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.091
|
|
|
|
cellular response to carbohydrate stimulus
|
GO:0071322 |
50 |
0.091
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
74 |
0.091
|
|
|
|
positive regulation of fatty acid oxidation
|
GO:0046321 |
4 |
0.091
|
Human |
|
|
positive regulation of fatty acid beta oxidation
|
GO:0032000 |
1 |
0.090
|
Human |
|
|
regulation of catenin import into nucleus
|
GO:0035412 |
5 |
0.090
|
|
|
|
positive regulation of glucose transport
|
GO:0010828 |
16 |
0.090
|
Human |
|
|
sensory perception
|
GO:0007600 |
245 |
0.089
|
|
|
|
mesoderm development
|
GO:0007498 |
100 |
0.089
|
|
|
|
limb development
|
GO:0060173 |
166 |
0.089
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.088
|
Human Mouse Rat |
|
|
glial cell development
|
GO:0021782 |
54 |
0.087
|
|
|
|
central nervous system neuron development
|
GO:0021954 |
67 |
0.087
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.087
|
|
|
|
homotypic cell cell adhesion
|
GO:0034109 |
28 |
0.087
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.087
|
|
|
|
regulation of cartilage development
|
GO:0061035 |
44 |
0.086
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
139 |
0.086
|
|
|
|
positive regulation of peptide secretion
|
GO:0002793 |
33 |
0.086
|
Mouse Rat |
|
|
positive regulation of cell cycle
|
GO:0045787 |
92 |
0.086
|
|
|
|
neuron projection extension
|
GO:1990138 |
64 |
0.086
|
|
|
|
negative regulation of fatty acid transport
|
GO:2000192 |
1 |
0.085
|
|
|
|
negative regulation of mesenchymal cell proliferation
|
GO:0072201 |
3 |
0.085
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.085
|
Mouse Rat |
|
|
cerebellum vasculature morphogenesis
|
GO:0061301 |
1 |
0.085
|
|
|
|
ear morphogenesis
|
GO:0042471 |
118 |
0.084
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.084
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.084
|
Mouse |
|
|
fasciculation of motor neuron axon
|
GO:0097156 |
2 |
0.084
|
|
|
|
regulation of b cell proliferation
|
GO:0030888 |
39 |
0.084
|
Mouse |
|
|
peptide hormone secretion
|
GO:0030072 |
109 |
0.084
|
Human Mouse Rat |
|
|
gonad development
|
GO:0008406 |
141 |
0.084
|
|
|
|
regulation of cell size
|
GO:0008361 |
72 |
0.083
|
|
|
|
layer formation in cerebral cortex
|
GO:0021819 |
13 |
0.083
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
88 |
0.083
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.083
|
|
|
|
regulation of cellular response to insulin stimulus
|
GO:1900076 |
30 |
0.083
|
Human Rat |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.082
|
|
|
|
glucose homeostasis
|
GO:0042593 |
128 |
0.082
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.082
|
Mouse |
|
|
organelle fission
|
GO:0048285 |
170 |
0.082
|
|
|
|
positive regulation of peptidyl serine phosphorylation
|
GO:0033138 |
25 |
0.082
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.082
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.081
|
|
|
|
retina morphogenesis in camera type eye
|
GO:0060042 |
45 |
0.081
|
|
|
|
regulation of tight junction assembly
|
GO:2000810 |
2 |
0.081
|
|
|
|
heart trabecula formation
|
GO:0060347 |
14 |
0.081
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
138 |
0.081
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.081
|
Mouse |
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
81 |
0.081
|
|
|
|
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090100 |
43 |
0.080
|
|
|
|
myotube cell development
|
GO:0014904 |
60 |
0.080
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.080
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.079
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.079
|
|
|
|
cell maturation
|
GO:0048469 |
127 |
0.078
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.078
|
|
|
|
establishment of planar polarity involved in neural tube closure
|
GO:0090177 |
15 |
0.078
|
|
|
|
mammary gland epithelium development
|
GO:0061180 |
65 |
0.078
|
|
|
|
phosphatidylinositol phosphorylation
|
GO:0046854 |
23 |
0.078
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.078
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
93 |
0.077
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.077
|
|
|
|
striated muscle cell proliferation
|
GO:0014855 |
39 |
0.076
|
|
|
|
regulation of jun kinase activity
|
GO:0043506 |
40 |
0.076
|
|
|
|
hindbrain radial glia guided cell migration
|
GO:0021932 |
12 |
0.075
|
|
|
|
photoreceptor cell development
|
GO:0042461 |
40 |
0.075
|
|
|
|
metencephalon development
|
GO:0022037 |
89 |
0.075
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.075
|
|
|
|
fatty acid transmembrane transport
|
GO:1902001 |
1 |
0.075
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.074
|
|
|
|
endocrine system development
|
GO:0035270 |
98 |
0.074
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
74 |
0.074
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.073
|
|
|
|
central nervous system projection neuron axonogenesis
|
GO:0021952 |
21 |
0.073
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.073
|
|
|
|
dendritic spine organization
|
GO:0097061 |
26 |
0.073
|
|
|
|
positive regulation of stem cell proliferation
|
GO:2000648 |
59 |
0.072
|
|
|
|
negative regulation of catenin import into nucleus
|
GO:0035414 |
2 |
0.072
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
79 |
0.072
|
|
|
|
cerebellum development
|
GO:0021549 |
77 |
0.072
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.071
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.071
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.071
|
|
|
|
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly
|
GO:0045899 |
2 |
0.071
|
|
|
|
positive regulation of long term neuronal synaptic plasticity
|
GO:0048170 |
3 |
0.071
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.071
|
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.070
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.070
|
|
|
|
embryonic camera type eye development
|
GO:0031076 |
36 |
0.070
|
|
|
|
oocyte maturation
|
GO:0001556 |
18 |
0.070
|
|
|
|
cell fate specification
|
GO:0001708 |
72 |
0.070
|
|
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
30 |
0.070
|
|
|
|
positive regulation of b cell proliferation
|
GO:0030890 |
24 |
0.070
|
Mouse |
|
|
forebrain development
|
GO:0030900 |
302 |
0.069
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
24 |
0.069
|
Fly |
|
|
development of primary female sexual characteristics
|
GO:0046545 |
73 |
0.069
|
|
