Mus musculus

55 known processes

Irx2

Iroquois related homeobox 2 (Drosophila)

(Aliases: MGC103290,IRX6)

Irx2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
tendon sheath development GO:0002932 1 0.931
Mouse
specification of loop of henle identity GO:0072086 4 0.838
embryonic organ morphogenesis GO:0048562 276 0.688
morphogenesis of embryonic epithelium GO:0016331 159 0.646
camera type eye development GO:0043010 266 0.602
Zebrafish Mouse
renal system development GO:0072001 225 0.590
specification of nephron tubule identity GO:0072081 5 0.573
tube formation GO:0035148 140 0.568
epithelial tube formation GO:0072175 130 0.560
pattern specification involved in metanephros development GO:0072268 4 0.535
embryonic epithelial tube formation GO:0001838 130 0.523
kidney development GO:0001822 213 0.506
cell fate commitment GO:0045165 210 0.501
tendon cell differentiation GO:0035990 4 0.498
Mouse
axonogenesis GO:0007409 274 0.476
Fly
ear morphogenesis GO:0042471 118 0.462
positive regulation of cell development GO:0010720 237 0.458
Mouse
sensory organ morphogenesis GO:0090596 242 0.444
Zebrafish Mouse Fly
loop of henle development GO:0072070 10 0.424
metanephros development GO:0001656 79 0.405
ear development GO:0043583 200 0.399
neural tube development GO:0021915 160 0.397
neuron maturation GO:0042551 29 0.397
Mouse
tendon formation GO:0035992 4 0.393
Mouse
regulation of cellular amino acid metabolic process GO:0006521 5 0.393
regulation of organ morphogenesis GO:2000027 144 0.387
urogenital system development GO:0001655 261 0.370
regulation of neuron differentiation GO:0045664 281 0.362
Mouse
segmentation GO:0035282 93 0.360
negative regulation of cell development GO:0010721 169 0.349
Mouse
skeletal system development GO:0001501 356 0.348
regionalization GO:0003002 337 0.337
developmental maturation GO:0021700 193 0.336
Mouse
appendage development GO:0048736 166 0.335
Fly
regulation of system process GO:0044057 200 0.333
Mouse
kidney epithelium development GO:0072073 121 0.326
epithelial tube morphogenesis GO:0060562 303 0.325
retinal bipolar neuron differentiation GO:0060040 5 0.323
Mouse
embryonic appendage morphogenesis GO:0035113 126 0.312
appendage morphogenesis GO:0035107 149 0.302
Fly
morphogenesis of a branching structure GO:0001763 203 0.294
muscle cell differentiation GO:0042692 261 0.292
Mouse
cell maturation GO:0048469 127 0.287
Mouse
neuron projection guidance GO:0097485 141 0.282
Fly
nephron tubule development GO:0072080 84 0.282
chemotaxis GO:0006935 247 0.280
Fly
axon guidance GO:0007411 141 0.267
Fly
regulation of cellular ketone metabolic process GO:0010565 66 0.251
positive regulation of neuron differentiation GO:0045666 141 0.235
Mouse
neural tube formation GO:0001841 108 0.231
positive regulation of nervous system development GO:0051962 221 0.225
Mouse
cellular amino acid metabolic process GO:0006520 103 0.224
regulation of neuron projection development GO:0010975 169 0.220
central nervous system neuron differentiation GO:0021953 162 0.218
blood circulation GO:0008015 195 0.216
Mouse
nephron morphogenesis GO:0072028 69 0.213
regulation of cellular amine metabolic process GO:0033238 20 0.211
stem cell development GO:0048864 219 0.211
developmental growth involved in morphogenesis GO:0060560 138 0.206
cardiac chamber development GO:0003205 108 0.204
muscle tissue development GO:0060537 308 0.198
Mouse
limb development GO:0060173 166 0.196
primary neural tube formation GO:0014020 95 0.193
telencephalon development GO:0021537 186 0.193
nephron development GO:0072006 109 0.190
inner ear morphogenesis GO:0042472 101 0.189
cellular response to growth factor stimulus GO:0071363 197 0.187
cell type specific apoptotic process GO:0097285 268 0.183
renal tubule development GO:0061326 87 0.182
negative regulation of nervous system development GO:0051961 156 0.182
Mouse
negative regulation of cell proliferation GO:0008285 296 0.181
cerebral cortex development GO:0021987 86 0.179
negative regulation of myoblast differentiation GO:0045662 18 0.179
Mouse
nephron epithelium morphogenesis GO:0072088 68 0.179
embryonic skeletal system development GO:0048706 120 0.175
digestive tract morphogenesis GO:0048546 147 0.174
kidney morphogenesis GO:0060993 83 0.174
pallium development GO:0021543 120 0.174
epidermis development GO:0008544 187 0.172
nephron epithelium development GO:0072009 92 0.168
establishment of planar polarity GO:0001736 28 0.165
Fly
heart morphogenesis GO:0003007 178 0.163
morphogenesis of a polarized epithelium GO:0001738 37 0.163
Fly
myotube differentiation GO:0014902 105 0.160
Mouse
epithelial cell development GO:0002064 159 0.158
Fly
skeletal system morphogenesis GO:0048705 203 0.157
forebrain development GO:0030900 302 0.155
connective tissue development GO:0061448 179 0.155
Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.154
nucleotide catabolic process GO:0009166 217 0.152
cardiac chamber morphogenesis GO:0003206 93 0.149
heart contraction GO:0060047 93 0.149
Mouse
morphogenesis of a branching epithelium GO:0061138 193 0.147
regulation of cell projection organization GO:0031344 206 0.146
negative regulation of neuron differentiation GO:0045665 101 0.146
Mouse
metanephric nephron development GO:0072210 34 0.145
retina development in camera type eye GO:0060041 119 0.144
Zebrafish Mouse
multicellular organismal macromolecule metabolic process GO:0044259 19 0.142
Mouse
embryonic skeletal system morphogenesis GO:0048704 91 0.141
neural retina development GO:0003407 41 0.141
Mouse
tube closure GO:0060606 91 0.140
dendrite development GO:0016358 115 0.139
establishment of planar polarity involved in neural tube closure GO:0090177 15 0.139
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.135
limb morphogenesis GO:0035108 149 0.131
regulation of neuron death GO:1901214 134 0.131
ras protein signal transduction GO:0007265 77 0.131
tendon development GO:0035989 6 0.131
Mouse
striated muscle tissue development GO:0014706 293 0.129
Mouse
gland development GO:0048732 330 0.128
cellular ketone metabolic process GO:0042180 84 0.126
neural tube closure GO:0001843 90 0.126
regulation of establishment of planar polarity GO:0090175 28 0.125
epithelial cell proliferation GO:0050673 174 0.124
regulation of protein localization GO:0032880 231 0.124
rho protein signal transduction GO:0007266 32 0.123
sensory neuron axon guidance GO:0097374 3 0.118
Fly
ossification GO:0001503 216 0.116
amine metabolic process GO:0009308 45 0.116
retina morphogenesis in camera type eye GO:0060042 45 0.114
Zebrafish Mouse
nephron tubule formation GO:0072079 20 0.113
spinal cord development GO:0021510 81 0.113
myotube cell development GO:0014904 60 0.113
Mouse
ameboidal type cell migration GO:0001667 128 0.112
cell growth GO:0016049 130 0.112
extracellular matrix organization GO:0030198 147 0.112
Mouse
embryonic heart tube morphogenesis GO:0003143 51 0.112
cellular amine metabolic process GO:0044106 44 0.112
cell adhesion GO:0007155 329 0.107
mesoderm development GO:0007498 100 0.105
Mouse
establishment of tissue polarity GO:0007164 28 0.105
Fly
skeletal muscle fiber development GO:0048741 58 0.103
Mouse
muscle fiber development GO:0048747 76 0.103
Mouse
cerebellum development GO:0021549 77 0.103
neuron projection extension GO:1990138 64 0.102
regulation of multicellular organismal metabolic process GO:0044246 14 0.100
Mouse
negative regulation of synapse assembly GO:0051964 3 0.100
myoblast differentiation GO:0045445 52 0.099
Mouse
positive regulation of cell motility GO:2000147 116 0.098
embryonic limb morphogenesis GO:0030326 126 0.097
positive regulation of protein modification process GO:0031401 299 0.097
respiratory system development GO:0060541 190 0.097
synaptic transmission GO:0007268 329 0.096
Worm
wnt signaling pathway planar cell polarity pathway GO:0060071 27 0.096
striated muscle cell development GO:0055002 125 0.096
Mouse
glial cell differentiation GO:0010001 131 0.096
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.095
branching morphogenesis of an epithelial tube GO:0048754 159 0.093
heart process GO:0003015 94 0.093
Mouse
extracellular structure organization GO:0043062 148 0.093
Mouse
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.090
body morphogenesis GO:0010171 45 0.090
Worm
skin development GO:0043588 220 0.089
regulation of neuron apoptotic process GO:0043523 122 0.089
regulation of wnt signaling pathway GO:0030111 123 0.089
canonical wnt signaling pathway GO:0060070 130 0.089
digestive tract development GO:0048565 190 0.088
negative regulation of muscle cell differentiation GO:0051148 33 0.088
Mouse
neural crest cell differentiation GO:0014033 54 0.087
somitogenesis GO:0001756 69 0.087
paraxial mesodermal cell differentiation GO:0048342 2 0.087
gastrulation GO:0007369 116 0.086
multicellular organismal metabolic process GO:0044236 28 0.086
Mouse
negative regulation of intracellular signal transduction GO:1902532 167 0.085
gliogenesis GO:0042063 141 0.085
metencephalon development GO:0022037 89 0.085
inorganic ion transmembrane transport GO:0098660 234 0.085
positive regulation of transferase activity GO:0051347 167 0.082
regulation of blood circulation GO:1903522 93 0.081
Mouse
embryonic heart tube development GO:0035050 65 0.081
blood vessel morphogenesis GO:0048514 285 0.081
cardiac ventricle development GO:0003231 83 0.081
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.081
organic hydroxy compound metabolic process GO:1901615 203 0.079
synapse organization GO:0050808 125 0.078
regulation of cell motility GO:2000145 236 0.077
skeletal muscle organ development GO:0060538 163 0.077
Mouse
positive regulation of protein phosphorylation GO:0001934 242 0.076
ion transmembrane transport GO:0034220 361 0.076
hair follicle development GO:0001942 85 0.076
digestive system development GO:0055123 200 0.076
negative regulation of cellular component organization GO:0051129 194 0.075
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.074
cardiac septum morphogenesis GO:0060411 46 0.073
transmembrane transport GO:0055085 412 0.073
cerebral cortex cell migration GO:0021795 44 0.073
cell differentiation in spinal cord GO:0021515 53 0.073
metal ion homeostasis GO:0055065 189 0.072
mesonephric duct morphogenesis GO:0072180 4 0.072
non canonical wnt signaling pathway GO:0035567 33 0.072
negative regulation of cellular protein metabolic process GO:0032269 247 0.072
single organismal cell cell adhesion GO:0016337 131 0.072
mitotic cell cycle GO:0000278 195 0.071
planar cell polarity pathway involved in pericardium morphogenesis GO:0061354 2 0.071
fat cell differentiation GO:0045444 160 0.071
mammary gland epithelium development GO:0061180 65 0.071
regulation of cellular response to stress GO:0080135 159 0.071
somite development GO:0061053 81 0.070
lens development in camera type eye GO:0002088 62 0.070
cell division GO:0051301 120 0.070
cartilage development GO:0051216 140 0.069
regulation of bmp signaling pathway GO:0030510 60 0.069
renal vesicle induction GO:0072034 3 0.067
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.067
sensory perception GO:0007600 245 0.067
determination of left right symmetry GO:0007368 80 0.067
epithelial to mesenchymal transition GO:0001837 47 0.066
positive regulation of neuron projection development GO:0010976 79 0.066
synaptic transmission gabaergic GO:0051932 19 0.065
Worm
stem cell proliferation GO:0072089 117 0.065
purine nucleoside triphosphate metabolic process GO:0009144 226 0.064
negative regulation of protein modification process GO:0031400 163 0.063
stem cell differentiation GO:0048863 268 0.063
outflow tract morphogenesis GO:0003151 53 0.063
regulation of kinase activity GO:0043549 249 0.063
proximal distal pattern formation involved in nephron development GO:0072047 5 0.063
positive regulation of cell cycle GO:0045787 92 0.062
mesoderm morphogenesis GO:0048332 64 0.062
formation of primary germ layer GO:0001704 77 0.062
protein maturation GO:0051604 176 0.062
nephron tubule morphogenesis GO:0072078 68 0.061
oviduct development GO:0060066 3 0.061
negative regulation of cell cycle GO:0045786 123 0.060
hippocampus development GO:0021766 52 0.060
positive regulation of kinase activity GO:0033674 155 0.060
establishment or maintenance of cell polarity GO:0007163 86 0.060
Fly
regulation of response to wounding GO:1903034 189 0.059
central nervous system morphogenesis GO:0021551 2 0.059
small gtpase mediated signal transduction GO:0007264 97 0.059
purine ribonucleoside catabolic process GO:0046130 205 0.059
positive regulation of cellular amine metabolic process GO:0033240 5 0.058
collagen metabolic process GO:0032963 17 0.058
Mouse
mapk cascade GO:0000165 281 0.058
wnt signaling pathway GO:0016055 188 0.057
regulation of cell growth GO:0001558 91 0.057
stem cell maintenance GO:0019827 130 0.057
odontogenesis GO:0042476 78 0.057
regulation of transferase activity GO:0051338 263 0.057
response to acid chemical GO:0001101 111 0.057
axis elongation involved in somitogenesis GO:0090245 4 0.057
metanephric loop of henle development GO:0072236 4 0.056
protein localization to organelle GO:0033365 185 0.056
smoothened signaling pathway GO:0007224 105 0.055
Fly
cardiac muscle tissue morphogenesis GO:0055008 44 0.055
midbrain hindbrain boundary maturation GO:0021732 1 0.055
bone development GO:0060348 120 0.055
mesonephric duct formation GO:0072181 2 0.055
mitotic cell cycle process GO:1903047 159 0.055
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.055
regulation of secretion by cell GO:1903530 249 0.054
determination of heart left right asymmetry GO:0061371 48 0.054
forebrain neuron development GO:0021884 30 0.054
angiogenesis GO:0001525 201 0.054
cation homeostasis GO:0055080 212 0.054
anion transport GO:0006820 177 0.053
cytokine production GO:0001816 319 0.053
endodermal cell fate specification GO:0001714 4 0.053
response to amino acid GO:0043200 37 0.052
response to organonitrogen compound GO:0010243 246 0.052
mesenchymal cell development GO:0014031 93 0.052
positive regulation of cell projection organization GO:0031346 95 0.051
forebrain generation of neurons GO:0021872 63 0.051
ribonucleoside metabolic process GO:0009119 245 0.051
regulation of epithelial cell proliferation GO:0050678 141 0.051
trabecula morphogenesis GO:0061383 40 0.051
ribonucleoside catabolic process GO:0042454 206 0.051
protein processing GO:0016485 163 0.051
neuron fate specification GO:0048665 30 0.050
artery development GO:0060840 53 0.050
regulation of heart rate GO:0002027 36 0.050
Mouse
aromatic compound catabolic process GO:0019439 286 0.050
renal system pattern specification GO:0072048 9 0.049
neuron migration GO:0001764 122 0.049
nucleoside metabolic process GO:0009116 246 0.049
nephric duct formation GO:0072179 4 0.049
hindbrain morphogenesis GO:0021575 46 0.048
lymphocyte differentiation GO:0030098 242 0.048
regulation of cellular catabolic process GO:0031329 242 0.048
regulation of actin filament based process GO:0032970 99 0.048
anion transmembrane transport GO:0098656 71 0.048
response to fibroblast growth factor GO:0071774 47 0.048
astrocyte differentiation GO:0048708 43 0.047
muscle cell development GO:0055001 133 0.047
Mouse
somatic stem cell maintenance GO:0035019 47 0.047
regulation of muscle tissue development GO:1901861 97 0.047
Mouse
blastocyst formation GO:0001825 33 0.046
mesoderm formation GO:0001707 62 0.046
tissue remodeling GO:0048771 102 0.046
positive regulation of mapk cascade GO:0043410 170 0.046
cation transport GO:0006812 399 0.046
planar cell polarity pathway involved in outflow tract morphogenesis GO:0061347 2 0.046
negative regulation of cellular amine metabolic process GO:0033239 1 0.045
segment specification GO:0007379 15 0.045
stress activated mapk cascade GO:0051403 80 0.045
cellular nitrogen compound catabolic process GO:0044270 280 0.045
jnk cascade GO:0007254 72 0.045
purine nucleoside triphosphate catabolic process GO:0009146 203 0.044
negative regulation of neuron projection development GO:0010977 50 0.044
sensory perception of sound GO:0007605 97 0.044
apoptotic signaling pathway GO:0097190 306 0.044
regulation of cell activation GO:0050865 289 0.044
negative regulation of protein metabolic process GO:0051248 282 0.043
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.043
regulation of cellular component biogenesis GO:0044087 181 0.043
developmental cell growth GO:0048588 84 0.043
regulation of embryonic development GO:0045995 71 0.043
cardiac septum development GO:0003279 59 0.043
epithelial cell morphogenesis GO:0003382 41 0.043
regulation of secretion GO:0051046 274 0.043
positive regulation of protein kinase activity GO:0045860 144 0.042
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.042
pattern specification involved in kidney development GO:0061004 8 0.042
organophosphate catabolic process GO:0046434 232 0.042
gonad development GO:0008406 141 0.042
hair follicle morphogenesis GO:0031069 29 0.042
bmp signaling pathway GO:0030509 93 0.042
keratinocyte differentiation GO:0030216 48 0.042
leukocyte differentiation GO:0002521 342 0.041
molting cycle GO:0042303 90 0.041
nucleoside phosphate metabolic process GO:0006753 338 0.041
non canonical wnt signaling pathway involved in heart development GO:0061341 3 0.041
nerve development GO:0021675 67 0.041
septum primum development GO:0003284 4 0.041
mesodermal cell migration GO:0008078 4 0.041
wound healing GO:0042060 157 0.041
microtubule based process GO:0007017 236 0.041
phenol containing compound metabolic process GO:0018958 60 0.040
positive regulation of cellular catabolic process GO:0031331 148 0.040
embryonic digit morphogenesis GO:0042733 56 0.040
negative regulation of growth GO:0045926 99 0.040
developmental induction GO:0031128 34 0.040
regulation of protein transport GO:0051223 163 0.040
regulation of canonical wnt signaling pathway GO:0060828 82 0.040
cytoplasmic transport GO:0016482 234 0.040
regulation of auditory receptor cell differentiation GO:0045607 4 0.040
negative regulation of molecular function GO:0044092 258 0.039
regulation of striated muscle cell differentiation GO:0051153 81 0.039
Mouse
positive regulation of organelle organization GO:0010638 128 0.039
transdifferentiation GO:0060290 1 0.039
planar cell polarity pathway involved in ventricular septum morphogenesis GO:0061348 2 0.039
regulation of organelle organization GO:0033043 289 0.039
purine nucleotide catabolic process GO:0006195 211 0.039
positive regulation of anagen GO:0051885 1 0.039
embryonic placenta development GO:0001892 98 0.039
inorganic cation transmembrane transport GO:0098662 207 0.039
autonomic nervous system development GO:0048483 43 0.038
odontogenesis of dentin containing tooth GO:0042475 66 0.038
neuromuscular process GO:0050905 99 0.038
regulation of mitotic cell cycle GO:0007346 126 0.038
neural precursor cell proliferation GO:0061351 121 0.038
palate development GO:0060021 76 0.038
telencephalon cell migration GO:0022029 55 0.038
regulation of binding GO:0051098 111 0.038
mammary gland duct morphogenesis GO:0060603 38 0.038
diencephalon development GO:0021536 63 0.038
regulation of body fluid levels GO:0050878 162 0.038
organelle fission GO:0048285 170 0.037
myoblast differentiation involved in skeletal muscle regeneration GO:0014835 3 0.037
ureteric bud development GO:0001657 94 0.037
regulation of extent of cell growth GO:0061387 52 0.037
purine nucleoside catabolic process GO:0006152 205 0.037
regulation of hormone levels GO:0010817 211 0.037
regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation GO:2000079 1 0.037
planar cell polarity pathway involved in cardiac right atrium morphogenesis GO:0061349 2 0.037
negative regulation of phosphorylation GO:0042326 166 0.037
negative regulation of response to wounding GO:1903035 77 0.037
maintenance of location GO:0051235 89 0.036
negative regulation of phosphate metabolic process GO:0045936 184 0.036
neuron apoptotic process GO:0051402 142 0.036
renal outer medulla development GO:0072054 2 0.036
forebrain cell migration GO:0021885 58 0.036
renal tubule morphogenesis GO:0061333 72 0.036
insulin secretion GO:0030073 89 0.036
regulation of protein kinase activity GO:0045859 232 0.036
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.036
regulation of intracellular transport GO:0032386 159 0.036
purine nucleoside metabolic process GO:0042278 241 0.036
negative regulation of protein phosphorylation GO:0001933 126 0.036
ventricular septum development GO:0003281 42 0.035
carbohydrate homeostasis GO:0033500 128 0.035
chromatin organization GO:0006325 206 0.035
ventral spinal cord interneuron fate commitment GO:0060579 14 0.035
developmental programmed cell death GO:0010623 41 0.035
planar cell polarity pathway involved in heart morphogenesis GO:0061346 3 0.035
regulation of lipid metabolic process GO:0019216 118 0.035
regulation of axon extension GO:0030516 43 0.035
regulation of cardiac muscle cell proliferation GO:0060043 23 0.035
locomotory behavior GO:0007626 195 0.035
positive regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation GO:2000081 1 0.035
trachea cartilage morphogenesis GO:0060535 4 0.035
guanosine containing compound metabolic process GO:1901068 144 0.034
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.034
Fly
regulation of osteoblast differentiation GO:0045667 67 0.034
positive regulation of rho gtpase activity GO:0032321 41 0.034
nucleoside triphosphate metabolic process GO:0009141 230 0.034
cilium morphogenesis GO:0060271 102 0.034
regulation of rho gtpase activity GO:0032319 58 0.034
regulation of ras gtpase activity GO:0032318 88 0.034
positive regulation of cell death GO:0010942 224 0.034
organic cyclic compound catabolic process GO:1901361 295 0.034
epithelium migration GO:0090132 63 0.034
cochlea morphogenesis GO:0090103 22 0.034
regulation of ossification GO:0030278 112 0.034
amide transport GO:0042886 138 0.034
regulation of ras protein signal transduction GO:0046578 114 0.034
regulation of endopeptidase activity GO:0052548 89 0.033
midbrain hindbrain boundary maturation during brain development GO:0022004 1 0.033
ribonucleoside triphosphate metabolic process GO:0009199 220 0.033
nucleoside triphosphate catabolic process GO:0009143 205 0.033
cellular response to organonitrogen compound GO:0071417 145 0.033
microtubule cytoskeleton organization GO:0000226 157 0.033
apoptotic process involved in morphogenesis GO:0060561 25 0.033
axis elongation GO:0003401 30 0.033
oocyte axis specification GO:0007309 2 0.033
peptide transport GO:0015833 133 0.033
regulation of cysteine type endopeptidase activity GO:2000116 65 0.032
multicellular organismal signaling GO:0035637 91 0.032
olfactory bulb development GO:0021772 30 0.032
regulation of retina development in camera type eye GO:1902866 3 0.032
organonitrogen compound biosynthetic process GO:1901566 192 0.032
action potential GO:0001508 78 0.032
lung development GO:0030324 164 0.032
hindbrain development GO:0030902 128 0.032
protein localization to nucleus GO:0034504 121 0.032
establishment of planar polarity of embryonic epithelium GO:0042249 16 0.032
carbohydrate derivative catabolic process GO:1901136 231 0.032
ribose phosphate metabolic process GO:0019693 291 0.032
astrocyte fate commitment GO:0060018 4 0.032
regulation of hydrolase activity GO:0051336 246 0.032
prostate gland development GO:0030850 48 0.032
cell fate specification GO:0001708 72 0.032
somatotropin secreting cell differentiation GO:0060126 4 0.032
organ growth GO:0035265 117 0.032
gas homeostasis GO:0033483 3 0.032
regulation of homeostatic process GO:0032844 182 0.032
peptidyl amino acid modification GO:0018193 336 0.032
lung morphogenesis GO:0060425 50 0.032
myeloid cell differentiation GO:0030099 233 0.032
respiratory tube development GO:0030323 167 0.032
cell cell adhesion GO:0098609 41 0.031
spemann organizer formation GO:0060061 2 0.031
neuron death GO:0070997 154 0.031
regulation of stem cell proliferation GO:0072091 78 0.031
anatomical structure maturation GO:0071695 49 0.031
cell fate determination GO:0001709 32 0.031
actin cytoskeleton organization GO:0030036 220 0.031
germ cell development GO:0007281 185 0.031
Fly
regulation of cardioblast differentiation GO:0051890 3 0.031
mesenchymal cell differentiation GO:0048762 107 0.031
paramesonephric duct development GO:0061205 3 0.031
mitochondrion organization GO:0007005 134 0.031
central nervous system vasculogenesis GO:0022009 3 0.031
placenta development GO:0001890 140 0.031
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.031
adaptive immune response GO:0002250 155 0.031
nitrogen compound transport GO:0071705 271 0.031
negative regulation of bmp signaling pathway GO:0030514 35 0.031
trophectodermal cell differentiation GO:0001829 21 0.031
regulation of proteolysis GO:0030162 164 0.030
cerebellar granule cell precursor proliferation GO:0021930 10 0.030
endocrine system development GO:0035270 98 0.030
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.030
heart trabecula formation GO:0060347 14 0.030
response to nutrient levels GO:0031667 109 0.030
regulation of cytoplasmic transport GO:1903649 112 0.030
schwann cell development GO:0014044 22 0.030
endomembrane system organization GO:0010256 147 0.030
regulation of myotube differentiation GO:0010830 62 0.030
Mouse
intracellular protein transport GO:0006886 204 0.030
paraxial mesodermal cell fate commitment GO:0048343 2 0.030
mesonephric tubule development GO:0072164 94 0.030
circulatory system process GO:0003013 197 0.030
Mouse
regulation of gtp catabolic process GO:0033124 113 0.030
glycosyl compound catabolic process GO:1901658 206 0.030
regulation of stem cell differentiation GO:2000736 50 0.029
regulation of epithelial to mesenchymal transition GO:0010717 22 0.029
cation transmembrane transport GO:0098655 266 0.029
forebrain neuron differentiation GO:0021879 52 0.029
regulation of nucleoside metabolic process GO:0009118 130 0.029
regulation of epidermis development GO:0045682 33 0.029
single organism cell adhesion GO:0098602 156 0.029
hypophysis morphogenesis GO:0048850 3 0.029
regulation of establishment of protein localization GO:0070201 181 0.029
tissue migration GO:0090130 68 0.029
purine ribonucleoside metabolic process GO:0046128 241 0.029
lung induction GO:0060492 3 0.029
organonitrogen compound catabolic process GO:1901565 264 0.028
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.028
negative regulation of neuron death GO:1901215 98 0.028
establishment of protein localization to organelle GO:0072594 118 0.028
negative regulation of cell adhesion GO:0007162 45 0.028
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.028
hair cycle GO:0042633 90 0.028
spinal cord dorsal ventral patterning GO:0021513 23 0.028
purine ribonucleotide metabolic process GO:0009150 290 0.028
regulation of cartilage development GO:0061035 44 0.028
lateral inhibition GO:0046331 1 0.028
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.028
specification of organ identity GO:0010092 30 0.028
cell proliferation in hindbrain GO:0021534 10 0.028

Irx2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org