Mus musculus

68 known processes

Itga3

integrin alpha 3

(Aliases: AA407068,CD49C)

Itga3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular component assembly involved in morphogenesis GO:0010927 139 0.992
formation of radial glial scaffolds GO:0021943 4 0.983
salivary gland morphogenesis GO:0007435 33 0.981
Fly
single organismal cell cell adhesion GO:0016337 131 0.974
Mouse Worm
morphogenesis of a polarized epithelium GO:0001738 37 0.961
actin cytoskeleton organization GO:0030036 220 0.959
Fly
gland development GO:0048732 330 0.959
Fly
actin filament organization GO:0007015 113 0.935
Fly
branching involved in salivary gland morphogenesis GO:0060445 26 0.889
leukocyte proliferation GO:0070661 172 0.870
Mouse
regulation of organelle organization GO:0033043 289 0.844
urogenital system development GO:0001655 261 0.839
Human Mouse
cell chemotaxis GO:0060326 81 0.816
Mouse
positive regulation of proteolysis GO:0045862 85 0.814
peptidyl tyrosine phosphorylation GO:0018108 143 0.811
ras protein signal transduction GO:0007265 77 0.804
retina vasculature morphogenesis in camera type eye GO:0061299 10 0.798
retinal blood vessel morphogenesis GO:0061304 3 0.798
organelle assembly GO:0070925 177 0.796
cilium assembly GO:0042384 81 0.742
lymphocyte proliferation GO:0046651 164 0.725
Mouse
small gtpase mediated signal transduction GO:0007264 97 0.717
dendritic spine organization GO:0097061 26 0.713
integrin mediated signaling pathway GO:0007229 27 0.710
branching morphogenesis of an epithelial tube GO:0048754 159 0.709
regulation of cardioblast differentiation GO:0051890 3 0.706
regulation of neurotransmitter levels GO:0001505 87 0.704
epithelial tube morphogenesis GO:0060562 303 0.700
neuron projection guidance GO:0097485 141 0.697
Fly
skeletal muscle organ development GO:0060538 163 0.692
Fly
chemotaxis GO:0006935 247 0.689
Mouse Fly
body morphogenesis GO:0010171 45 0.678
Worm
regulation of cysteine type endopeptidase activity GO:2000116 65 0.678
substrate dependent cell migration GO:0006929 18 0.665
Mouse
regulation of protein kinase activity GO:0045859 232 0.661
establishment or maintenance of cell polarity GO:0007163 86 0.657
smooth muscle cell migration GO:0014909 10 0.654
cilium morphogenesis GO:0060271 102 0.633
negative regulation of rho protein signal transduction GO:0035024 7 0.625
odontogenesis GO:0042476 78 0.618
Mouse
cellular amino acid metabolic process GO:0006520 103 0.614
morphogenesis of a branching epithelium GO:0061138 193 0.609
cell adhesion GO:0007155 329 0.607
Mouse Worm Fly
axonogenesis GO:0007409 274 0.600
Fly
single organism cell adhesion GO:0098602 156 0.593
Mouse Worm
positive regulation of protein modification process GO:0031401 299 0.577
membrane organization GO:0061024 245 0.572
Human
salivary gland development GO:0007431 37 0.567
Fly
positive regulation of cell migration GO:0030335 109 0.565
Mouse
regulation of cell shape GO:0008360 39 0.560
morphogenesis of embryonic epithelium GO:0016331 159 0.557
regulation of rho protein signal transduction GO:0035023 71 0.554
digestive tract development GO:0048565 190 0.514
Human Worm
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.514
cell recognition GO:0008037 83 0.504
Worm Fly
regulation of cell adhesion GO:0030155 154 0.497
Mouse
negative regulation of intracellular signal transduction GO:1902532 167 0.495
positive regulation of cell projection organization GO:0031346 95 0.495
regulation of cytoskeleton organization GO:0051493 122 0.488
negative regulation of phosphate metabolic process GO:0045936 184 0.482
negative regulation of cell migration GO:0030336 59 0.480
neurotransmitter transport GO:0006836 76 0.478
muscle cell development GO:0055001 133 0.474
regulation of cellular ketone metabolic process GO:0010565 66 0.472
regulation of cellular component biogenesis GO:0044087 181 0.472
mesangial cell differentiation GO:0072007 4 0.471
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.470
kidney development GO:0001822 213 0.466
Human Mouse
trunk neural crest cell migration GO:0036484 4 0.464
angiogenesis GO:0001525 201 0.464
regulation of transferase activity GO:0051338 263 0.462
actin filament bundle assembly GO:0051017 40 0.461
metanephric glomerular mesangial cell proliferation involved in metanephros development GO:0072262 3 0.459
purine ribonucleoside catabolic process GO:0046130 205 0.458
substrate dependent cell migration cell extension GO:0006930 4 0.458
planar cell polarity pathway involved in heart morphogenesis GO:0061346 3 0.456
establishment of protein localization to plasma membrane GO:0090002 34 0.452
Human
muscle cell differentiation GO:0042692 261 0.450
Mouse
regulation of hydrolase activity GO:0051336 246 0.449
morphogenesis of a branching structure GO:0001763 203 0.449
regulation of cell activation GO:0050865 289 0.444
Mouse
endocytosis GO:0006897 168 0.443
Mouse Worm
metanephric glomerular mesangium development GO:0072223 3 0.437
amine metabolic process GO:0009308 45 0.430
planar cell polarity pathway involved in pericardium morphogenesis GO:0061354 2 0.429
synaptic transmission GO:0007268 329 0.429
negative regulation of ras protein signal transduction GO:0046580 18 0.427
guanosine containing compound catabolic process GO:1901069 144 0.425
positive regulation of rho gtpase activity GO:0032321 41 0.424
central nervous system projection neuron axonogenesis GO:0021952 21 0.423
negative regulation of protein phosphorylation GO:0001933 126 0.419
canonical wnt signaling pathway involved in heart development GO:0061316 3 0.409
neuron projection extension GO:1990138 64 0.409
establishment of planar polarity GO:0001736 28 0.408
mapk cascade GO:0000165 281 0.406
Mouse
regulation of smooth muscle cell migration GO:0014910 6 0.402
branchiomotor neuron axon guidance GO:0021785 7 0.402
regulation of cellular catabolic process GO:0031329 242 0.400
canonical wnt signaling pathway involved in regulation of cell proliferation GO:0044340 3 0.398
negative regulation of smooth muscle cell migration GO:0014912 2 0.388
lung induction GO:0060492 3 0.388
regulation of neuron projection development GO:0010975 169 0.382
apoptotic signaling pathway GO:0097190 306 0.382
Mouse
sensory organ morphogenesis GO:0090596 242 0.375
Mouse
neural tube development GO:0021915 160 0.373
neuron apoptotic process GO:0051402 142 0.369
rho protein signal transduction GO:0007266 32 0.368
regulation of actin cytoskeleton organization GO:0032956 84 0.368
regulation of membrane potential GO:0042391 192 0.366
female meiosis chromosome segregation GO:0016321 1 0.364
regulation of mapk cascade GO:0043408 248 0.362
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.360
positive regulation of smooth muscle cell migration GO:0014911 4 0.357
morphogenesis of an epithelial sheet GO:0002011 27 0.354
planar cell polarity pathway involved in ventricular septum morphogenesis GO:0061348 2 0.348
positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 3 0.344
branching involved in ureteric bud morphogenesis GO:0001658 56 0.343
negative regulation of cell motility GO:2000146 61 0.342
establishment of monopolar cell polarity GO:0061162 8 0.341
positive regulation of dendrite development GO:1900006 21 0.340
regulation of protein serine threonine kinase activity GO:0071900 157 0.338
extrinsic apoptotic signaling pathway GO:0097191 126 0.338
Mouse
placenta development GO:0001890 140 0.337
Mouse
positive regulation of gtpase activity GO:0043547 85 0.337
regulation of endopeptidase activity GO:0052548 89 0.336
cd4 positive alpha beta t cell activation GO:0035710 45 0.336
ureteric bud development GO:0001657 94 0.335
oocyte axis specification GO:0007309 2 0.331
regulation of ras protein signal transduction GO:0046578 114 0.329
phospholipid metabolic process GO:0006644 87 0.328
negative regulation of phosphorylation GO:0042326 166 0.325
gastrulation GO:0007369 116 0.323
Human Worm
embryonic placenta development GO:0001892 98 0.323
Mouse
establishment of epithelial cell polarity GO:0090162 10 0.322
positive regulation of ras gtpase activity GO:0032320 65 0.320
regulation of myeloid dendritic cell activation GO:0030885 5 0.319
cell substrate adhesion GO:0031589 130 0.318
Mouse
stem cell differentiation GO:0048863 268 0.317
embryonic epithelial tube formation GO:0001838 130 0.317
lung vasculature development GO:0060426 7 0.316
establishment or maintenance of bipolar cell polarity GO:0061245 21 0.315
regulation of peptidase activity GO:0052547 96 0.312
regulation of leukocyte differentiation GO:1902105 159 0.310
Mouse
regulation of lymphocyte proliferation GO:0050670 117 0.306
Mouse
positive regulation of endopeptidase activity GO:0010950 43 0.305
positive regulation of transcription from rna polymerase ii promoter involved in smooth muscle cell differentiation GO:2000721 2 0.303
Mouse
gonad development GO:0008406 141 0.302
Worm
negative regulation of immune system process GO:0002683 209 0.298
cell junction organization GO:0034330 77 0.297
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.297
t cell activation GO:0042110 289 0.294
Mouse
substrate adhesion dependent cell spreading GO:0034446 30 0.294
t cell proliferation GO:0042098 120 0.293
Mouse
synapse assembly GO:0007416 56 0.290
cell substrate junction assembly GO:0007044 24 0.288
Mouse
development of primary sexual characteristics GO:0045137 143 0.288
Worm
negative regulation of protein metabolic process GO:0051248 282 0.286
branching involved in mammary gland duct morphogenesis GO:0060444 27 0.285
leukocyte migration GO:0050900 124 0.283
Mouse
regulation of cellular amino acid metabolic process GO:0006521 5 0.283
learning or memory GO:0007611 148 0.283
regulation of t cell proliferation GO:0042129 92 0.281
Mouse
metanephric glomerular epithelium development GO:0072244 3 0.279
immune effector process GO:0002252 321 0.278
Mouse
negative regulation of cell proliferation GO:0008285 296 0.278
gtp catabolic process GO:0006184 143 0.275
regulation of cellular amine metabolic process GO:0033238 20 0.274
neural tube formation GO:0001841 108 0.273
non canonical wnt signaling pathway involved in heart development GO:0061341 3 0.270
primary neural tube formation GO:0014020 95 0.269
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.267
regulation of heart growth GO:0060420 31 0.267
leukocyte differentiation GO:0002521 342 0.267
Mouse
regulation of glomerular mesangial cell proliferation GO:0072124 1 0.266
regulation of cell size GO:0008361 72 0.264
regulation of axon extension GO:0030516 43 0.264
mesenchyme development GO:0060485 152 0.263
regulation of neuron apoptotic process GO:0043523 122 0.262
positive regulation of cellular component biogenesis GO:0044089 94 0.262
cognition GO:0050890 149 0.261
regulation of cell migration GO:0030334 219 0.260
Mouse
positive regulation of purine nucleotide catabolic process GO:0033123 88 0.259
glial cell apoptotic process GO:0034349 3 0.257
sympathetic neuron projection guidance GO:0097491 4 0.257
negative regulation of synapse assembly GO:0051964 3 0.257
positive regulation of neuron projection development GO:0010976 79 0.256
filopodium assembly GO:0046847 19 0.256
Mouse
embryonic body morphogenesis GO:0010172 10 0.254
myosin filament assembly GO:0031034 2 0.254
protein maturation GO:0051604 176 0.254
ameboidal type cell migration GO:0001667 128 0.253
Worm
nephron tubule morphogenesis GO:0072078 68 0.253
sympathetic neuron projection extension GO:0097490 4 0.252
lymphocyte migration GO:0072676 26 0.251
Mouse
regulation of cardiac cell fate specification GO:2000043 1 0.251
regulation of osteoblast proliferation GO:0033688 15 0.250
Mouse
respiratory tube development GO:0030323 167 0.250
Human
platelet aggregation GO:0070527 20 0.247
organelle localization GO:0051640 179 0.247
cell matrix adhesion GO:0007160 68 0.245
Mouse
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.243
regulation of actin filament bundle assembly GO:0032231 18 0.242
negative regulation of cellular component organization GO:0051129 194 0.241
negative regulation of planar cell polarity pathway involved in pericardium morphogenesis GO:2000166 1 0.240
sprouting angiogenesis GO:0002040 26 0.237
positive regulation of protein autophosphorylation GO:0031954 4 0.236
outflow tract morphogenesis GO:0003151 53 0.234
striated muscle tissue development GO:0014706 293 0.233
gtp metabolic process GO:0046039 144 0.233
metanephric glomerular endothelium development GO:0072264 1 0.232
positive regulation of hydrolase activity GO:0051345 148 0.232
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.228
Mouse
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.226
actomyosin structure organization GO:0031032 56 0.225
release of cytochrome c from mitochondria GO:0001836 23 0.225
positive regulation of nucleotide catabolic process GO:0030813 88 0.224
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 14 0.222
regulation of apoptotic signaling pathway GO:2001233 197 0.222
nephron epithelium morphogenesis GO:0072088 68 0.220
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.219
Human Mouse
muscular septum morphogenesis GO:0003150 4 0.219
mesonephric tubule development GO:0072164 94 0.218
microtubule based process GO:0007017 236 0.216
cellular amine metabolic process GO:0044106 44 0.216
semaphorin plexin signaling pathway involved in neuron projection guidance GO:1902285 6 0.215
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 1 0.213
regulation of cell projection organization GO:0031344 206 0.211
positive regulation of mesenchymal cell proliferation GO:0002053 33 0.211
negative regulation of axon extension GO:0030517 19 0.210
memory GO:0007613 58 0.210
response to growth factor GO:0070848 198 0.209
Human Mouse
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.209
leukocyte chemotaxis GO:0030595 69 0.205
Mouse
brown fat cell differentiation GO:0050873 36 0.205
Mouse
motor neuron axon guidance GO:0008045 26 0.205
regulation of neuron differentiation GO:0045664 281 0.203
kidney mesenchyme morphogenesis GO:0072131 4 0.201
oviduct development GO:0060066 3 0.200
skeletal system development GO:0001501 356 0.199
cellular ketone metabolic process GO:0042180 84 0.198
dendrite development GO:0016358 115 0.198
positive regulation of cellular catabolic process GO:0031331 148 0.195
oocyte construction GO:0007308 2 0.194
sensory perception GO:0007600 245 0.193
Fly
positive regulation of cellular amine metabolic process GO:0033240 5 0.192
mitotic cell cycle process GO:1903047 159 0.192
protein localization to membrane GO:0072657 108 0.191
Human
regulation of planar cell polarity pathway involved in outflow tract morphogenesis GO:2000163 1 0.191
cell cell adhesion GO:0098609 41 0.191
Mouse
ribonucleoside catabolic process GO:0042454 206 0.190
regulation of protein localization GO:0032880 231 0.189
Human
regulation of stress fiber assembly GO:0051492 15 0.189
homotypic cell cell adhesion GO:0034109 28 0.188
inflammatory response GO:0006954 244 0.188
Mouse
regulation of immunoglobulin production GO:0002637 42 0.188
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 40 0.187
Mouse
respiratory system development GO:0060541 190 0.186
Human Fly
regulation of gtp catabolic process GO:0033124 113 0.184
planar cell polarity pathway involved in outflow tract morphogenesis GO:0061347 2 0.183
muscle cell migration GO:0014812 19 0.182
regulation of purine nucleotide metabolic process GO:1900542 169 0.181
positive regulation of leukocyte proliferation GO:0070665 73 0.181
Mouse
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.179
Human Mouse
renal system development GO:0072001 225 0.178
Human Mouse
inner medullary collecting duct development GO:0072061 2 0.177
epithelial cell morphogenesis GO:0003382 41 0.177
cardiac muscle cell development GO:0055013 39 0.176
multicellular organismal homeostasis GO:0048871 164 0.175
Mouse Fly
regulation of cell motility GO:2000145 236 0.175
Mouse
metanephric mesenchyme morphogenesis GO:0072133 4 0.175
retina vasculature development in camera type eye GO:0061298 17 0.174
myeloid leukocyte migration GO:0097529 57 0.173
Mouse
cardiac cell fate specification GO:0060912 2 0.173
negative regulation of cell activation GO:0050866 111 0.172
hindbrain radial glia guided cell migration GO:0021932 12 0.170
kidney morphogenesis GO:0060993 83 0.169
positive regulation of mapk cascade GO:0043410 170 0.169
regulation of planar cell polarity pathway involved in ventricular septum morphogenesis GO:2000148 1 0.169
positive regulation of cell adhesion GO:0045785 80 0.168
Mouse
myosin filament organization GO:0031033 3 0.168
positive regulation of protein phosphorylation GO:0001934 242 0.168
cell proliferation involved in kidney development GO:0072111 14 0.167
peptidyl tyrosine modification GO:0018212 145 0.164
blood vessel endothelial cell migration GO:0043534 23 0.164
regulation of lymphocyte differentiation GO:0045619 107 0.164
regulation of actin filament based process GO:0032970 99 0.163
cardiac right atrium morphogenesis GO:0003213 3 0.162
neural tube closure GO:0001843 90 0.162
regulation of nucleoside metabolic process GO:0009118 130 0.161
negative regulation of planar cell polarity pathway involved in heart morphogenesis GO:2000160 1 0.160
regulation of proteolysis GO:0030162 164 0.157
striated muscle myosin thick filament assembly GO:0071688 1 0.157
cardiac muscle tissue development GO:0048738 130 0.157
mesodermal cell migration GO:0008078 4 0.156
Worm
regulation of hippo signaling GO:0035330 1 0.156
regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072039 4 0.154
macromolecule catabolic process GO:0009057 281 0.153
Worm
central nervous system neuron axonogenesis GO:0021955 28 0.153
cellular protein complex assembly GO:0043623 116 0.153
microtubule cytoskeleton organization GO:0000226 157 0.152
neuron death GO:0070997 154 0.150
keratinocyte differentiation GO:0030216 48 0.149
central nervous system vasculogenesis GO:0022009 3 0.149
ureteric bud morphogenesis GO:0060675 62 0.148
vegf activated neuropilin signaling pathway GO:0038190 2 0.147
gonadotrophin releasing hormone neuronal migration to the hypothalamus GO:0021828 3 0.146
protein depolymerization GO:0051261 34 0.145
trachea cartilage morphogenesis GO:0060535 4 0.145
regulation of ion transport GO:0043269 215 0.144
corpus callosum development GO:0022038 10 0.144
establishment of endothelial blood brain barrier GO:0014045 3 0.143
dendritic spine maintenance GO:0097062 4 0.143
stem cell proliferation GO:0072089 117 0.143
brain morphogenesis GO:0048854 32 0.142
purine nucleoside metabolic process GO:0042278 241 0.142
myeloid cell differentiation GO:0030099 233 0.141
Mouse
axon extension involved in axon guidance GO:0048846 14 0.141
regulation of angiogenesis GO:0045765 81 0.140
male gamete generation GO:0048232 285 0.140
hemostasis GO:0007599 78 0.140
tissue migration GO:0090130 68 0.140
Worm
regulation of leukocyte proliferation GO:0070663 121 0.139
Mouse
lymphocyte differentiation GO:0030098 242 0.139
lung field specification GO:0060424 3 0.138
regulation of defense response GO:0031347 233 0.138
protein processing GO:0016485 163 0.138
t cell differentiation in thymus GO:0033077 77 0.137
endodermal cell fate specification GO:0001714 4 0.136
ventral trunk neural crest cell migration GO:0036486 4 0.135
regulation of protein processing GO:0070613 96 0.135
blood circulation GO:0008015 195 0.135
g1 s transition of mitotic cell cycle GO:0000082 57 0.134
striated muscle contraction GO:0006941 45 0.134
epidermis development GO:0008544 187 0.133
regulation of anatomical structure size GO:0090066 178 0.133
cranial nerve morphogenesis GO:0021602 26 0.132
endothelial cell migration GO:0043542 44 0.132
metencephalon development GO:0022037 89 0.132
vesicle localization GO:0051648 86 0.132
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.131
Human Mouse
regulation of ras gtpase activity GO:0032318 88 0.131
regulation of endothelial cell migration GO:0010594 22 0.130
regulation of cardiac muscle tissue development GO:0055024 31 0.130
response to misfolded protein GO:0051788 5 0.127
cellular lipid metabolic process GO:0044255 323 0.127
ribose phosphate metabolic process GO:0019693 291 0.127
ribonucleoside triphosphate catabolic process GO:0009203 199 0.127
activation of immune response GO:0002253 138 0.127
cytokine mediated signaling pathway GO:0019221 115 0.126
positive regulation of immunoglobulin production GO:0002639 28 0.126
retinal ganglion cell axon guidance GO:0031290 18 0.126
negative regulation of protein processing GO:0010955 79 0.125
negative regulation of neuron projection development GO:0010977 50 0.124
epiboly GO:0090504 8 0.123
negative regulation of cytoskeleton organization GO:0051494 36 0.122
osteoblast proliferation GO:0033687 18 0.122
Mouse
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.122
cellular response to x ray GO:0071481 2 0.122
regulation of jnk cascade GO:0046328 62 0.122
glomerular epithelial cell development GO:0072310 6 0.122
cardiac muscle cell differentiation GO:0055007 69 0.121
cranial nerve structural organization GO:0021604 13 0.121
negative regulation of cysteine type endopeptidase activity GO:2000117 22 0.120
neuronal action potential GO:0019228 54 0.120
meiotic nuclear division GO:0007126 115 0.119
lung morphogenesis GO:0060425 50 0.119
embryonic digit morphogenesis GO:0042733 56 0.118
negative regulation of neuron apoptotic process GO:0043524 92 0.118
regulation of body fluid levels GO:0050878 162 0.117
establishment of planar polarity involved in neural tube closure GO:0090177 15 0.117
organonitrogen compound catabolic process GO:1901565 264 0.117
transmission of nerve impulse GO:0019226 76 0.115
axon ensheathment GO:0008366 76 0.115
cell type specific apoptotic process GO:0097285 268 0.114
negative regulation of proteolysis GO:0045861 74 0.113
neural crest cell migration GO:0001755 32 0.113
learning GO:0007612 98 0.113
mammary gland alveolus development GO:0060749 22 0.113
cardiac endothelial cell differentiation GO:0003348 4 0.113
regulation of endocytosis GO:0030100 69 0.112
Mouse
regulation of epithelial to mesenchymal transition GO:0010717 22 0.112
granulocyte chemotaxis GO:0071621 39 0.112
Mouse
nephric duct formation GO:0072179 4 0.111
mesonephric epithelium development GO:0072163 94 0.110
leukocyte activation involved in immune response GO:0002366 126 0.110
camera type eye development GO:0043010 266 0.110
signal transduction involved in dna damage checkpoint GO:0072422 3 0.110
protein kinase b signaling GO:0043491 74 0.109
regulation of stress activated mapk cascade GO:0032872 69 0.107
positive regulation of jun kinase activity GO:0043507 30 0.107
regulation of establishment of protein localization GO:0070201 181 0.106
Human
nucleoside metabolic process GO:0009116 246 0.106
epithelial cell development GO:0002064 159 0.105
organic cyclic compound catabolic process GO:1901361 295 0.105
forebrain development GO:0030900 302 0.105
peptidyl amino acid modification GO:0018193 336 0.104
regulation of t cell activation GO:0050863 170 0.104
Mouse
positive regulation of t cell activation GO:0050870 101 0.103
Mouse
interleukin 5 secretion GO:0072603 2 0.103
anatomical structure arrangement GO:0048532 20 0.103
extracellular matrix organization GO:0030198 147 0.103
Mouse
protein autophosphorylation GO:0046777 61 0.102
regulation of rho gtpase activity GO:0032319 58 0.101
digestive tract morphogenesis GO:0048546 147 0.101
Human Worm
cerebral cortex tangential migration using cell axon interactions GO:0021824 3 0.101
developmental growth involved in morphogenesis GO:0060560 138 0.101
positive regulation of rac gtpase activity GO:0032855 14 0.100
axis elongation involved in somitogenesis GO:0090245 4 0.100
non canonical wnt signaling pathway via jnk cascade GO:0038031 3 0.100
cellular response to cytokine stimulus GO:0071345 189 0.099
synapse organization GO:0050808 125 0.099
purine nucleoside catabolic process GO:0006152 205 0.099
mesonephros development GO:0001823 97 0.099
mammary gland lobule development GO:0061377 22 0.099
response to radiation GO:0009314 165 0.098
developmental maturation GO:0021700 193 0.098
regulation of nucleotide metabolic process GO:0006140 169 0.098
regulation of protein ubiquitination GO:0031396 52 0.098
negative regulation of axon guidance GO:1902668 8 0.097
production of molecular mediator of immune response GO:0002440 103 0.097
renal vesicle induction GO:0072034 3 0.097
appendage development GO:0048736 166 0.095
Zebrafish Fly
regulation of branching involved in salivary gland morphogenesis by epithelial mesenchymal signaling GO:0060683 1 0.095
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.095
reactive oxygen species metabolic process GO:0072593 84 0.095
regulation of keratinocyte differentiation GO:0045616 11 0.094
purine nucleotide metabolic process GO:0006163 302 0.094
glycosyl compound catabolic process GO:1901658 206 0.094
planar cell polarity pathway involved in cardiac right atrium morphogenesis GO:0061349 2 0.094
positive regulation of nervous system development GO:0051962 221 0.093
hindbrain development GO:0030902 128 0.093
microglia differentiation GO:0014004 2 0.093
Mouse
regulation of endothelial cell chemotaxis GO:2001026 1 0.093
trunk segmentation GO:0035290 4 0.092
negative regulation of protein depolymerization GO:1901880 21 0.092
cerebellum development GO:0021549 77 0.092
receptor mediated endocytosis GO:0006898 51 0.091
Worm
facial nerve structural organization GO:0021612 10 0.091
metanephric glomerulus vasculature development GO:0072239 7 0.090
regulation of neuron death GO:1901214 134 0.090
positive regulation of neuron differentiation GO:0045666 141 0.090
epidermal growth factor receptor signaling pathway GO:0007173 28 0.090
Mouse
stress activated mapk cascade GO:0051403 80 0.090
multicellular organismal catabolic process GO:0044243 7 0.090
activation of ras gtpase activity GO:0032856 11 0.090
regulation of establishment of protein localization to plasma membrane GO:0090003 12 0.088
Human
facial nerve morphogenesis GO:0021610 11 0.088
establishment or maintenance of cytoskeleton polarity GO:0030952 2 0.088
positive regulation of map kinase activity GO:0043406 84 0.088
cerebrospinal fluid secretion GO:0033326 4 0.087
positive regulation of gtp catabolic process GO:0033126 85 0.087
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.087
mitochondrion organization GO:0007005 134 0.086
regulation of b cell activation GO:0050864 81 0.086
nucleoside catabolic process GO:0009164 206 0.086
epithelial cell migration GO:0010631 63 0.085
response to fibroblast growth factor GO:0071774 47 0.085
positive regulation of cell development GO:0010720 237 0.085
establishment of organelle localization GO:0051656 122 0.084
cell growth GO:0016049 130 0.084
positive regulation of apoptotic signaling pathway GO:2001235 95 0.084
activation of cysteine type endopeptidase activity GO:0097202 27 0.084
ribonucleoside metabolic process GO:0009119 245 0.084
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry GO:1900164 2 0.084
wnt signaling pathway planar cell polarity pathway GO:0060071 27 0.083
ventricular system development GO:0021591 27 0.083
rac protein signal transduction GO:0016601 13 0.083
formation of organ boundary GO:0010160 1 0.082
Fly
tube formation GO:0035148 140 0.081
negative regulation of protein modification process GO:0031400 163 0.081
purine nucleoside triphosphate metabolic process GO:0009144 226 0.081
positive regulation of mitotic cell cycle embryonic GO:0045977 2 0.081
negative regulation of cellular protein metabolic process GO:0032269 247 0.081
regulation of cardiac muscle tissue growth GO:0055021 26 0.081
semaphorin plexin signaling pathway involved in axon guidance GO:1902287 6 0.081
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.080
negative regulation of molecular function GO:0044092 258 0.080
regulation of epithelial cell proliferation GO:0050678 141 0.080
endomembrane system organization GO:0010256 147 0.080
Human
regulation of extent of cell growth GO:0061387 52 0.079
establishment of protein localization to membrane GO:0090150 54 0.079
Human
regulation of nucleotide catabolic process GO:0030811 122 0.079
dichotomous subdivision of terminal units involved in salivary gland branching GO:0060666 5 0.079
neurotrophin trk receptor signaling pathway GO:0048011 8 0.079
spermatid development GO:0007286 108 0.078
positive regulation of protein localization to plasma membrane GO:1903078 7 0.078
Human
leukocyte cell cell adhesion GO:0007159 14 0.078
Mouse
tertiary branching involved in mammary gland duct morphogenesis GO:0060748 3 0.078

Itga3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.155
cancer DOID:162 0 0.125
organ system cancer DOID:0050686 0 0.125
kidney cancer DOID:263 0 0.121
urinary system cancer DOID:3996 0 0.121
disease of anatomical entity DOID:7 0 0.102
urinary system disease DOID:18 0 0.102