|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.975
|
Mouse |
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.942
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.938
|
Mouse |
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.933
|
Mouse |
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.911
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.896
|
Human Mouse |
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.896
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.887
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.884
|
Mouse |
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.864
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.826
|
Fly |
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.818
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.813
|
Mouse Fly |
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.813
|
Mouse |
|
|
t cell activation
|
GO:0042110 |
289 |
0.801
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.792
|
|
|
|
cellular extravasation
|
GO:0045123 |
17 |
0.779
|
Mouse |
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.735
|
Mouse |
|
|
defense response to gram positive bacterium
|
GO:0050830 |
50 |
0.729
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.728
|
Human |
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.723
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.717
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.707
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.707
|
Mouse |
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.688
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.676
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.669
|
Mouse |
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.666
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.651
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.650
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.630
|
Mouse |
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.620
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.598
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.596
|
Mouse Fly |
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.595
|
Mouse |
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.592
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.591
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.591
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.589
|
Fly |
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.579
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.564
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.564
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.559
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.554
|
Mouse |
|
|
innate immune response
|
GO:0045087 |
157 |
0.543
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.537
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.535
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.530
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.527
|
|
|
|
negative thymic t cell selection
|
GO:0045060 |
12 |
0.527
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.521
|
Mouse |
|
|
digestive tract development
|
GO:0048565 |
190 |
0.515
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.509
|
|
|
|
lymphocyte migration
|
GO:0072676 |
26 |
0.509
|
Mouse |
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.503
|
Human |
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.499
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.497
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.494
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.488
|
Human |
|
|
axon guidance
|
GO:0007411 |
141 |
0.478
|
Fly |
|
|
granulocyte migration
|
GO:0097530 |
43 |
0.477
|
Mouse |
|
|
angiogenesis
|
GO:0001525 |
201 |
0.467
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.462
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.449
|
|
|
|
granulocyte chemotaxis
|
GO:0071621 |
39 |
0.444
|
Mouse |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.441
|
|
|
|
positive regulation of monocyte extravasation
|
GO:2000439 |
1 |
0.438
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.435
|
|
|
|
positive regulation of t cell extravasation
|
GO:2000409 |
2 |
0.428
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.426
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.425
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.421
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
40 |
0.421
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.416
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.414
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.412
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.410
|
Mouse |
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.405
|
|
|
|
leukocyte cell cell adhesion
|
GO:0007159 |
14 |
0.404
|
|
|
|
regulation of t cell costimulation
|
GO:2000523 |
2 |
0.401
|
|
|
|
positive regulation of cd8 positive alpha beta t cell extravasation
|
GO:2000451 |
2 |
0.398
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.397
|
|
|
|
negative regulation of synapse assembly
|
GO:0051964 |
3 |
0.391
|
Fly |
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.390
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
45 |
0.388
|
|
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.385
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
84 |
0.379
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.379
|
|
|
|
myeloid leukocyte mediated immunity
|
GO:0002444 |
42 |
0.371
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.371
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.369
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.367
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.366
|
Mouse |
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
104 |
0.366
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.359
|
Mouse |
|
|
neutrophil migration
|
GO:1990266 |
37 |
0.357
|
Mouse |
|
|
response to growth factor
|
GO:0070848 |
198 |
0.355
|
Mouse |
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.346
|
|
|
|
t cell selection
|
GO:0045058 |
34 |
0.346
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
49 |
0.344
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.344
|
Mouse |
|
|
negative regulation of innate immune response
|
GO:0045824 |
17 |
0.341
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.339
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.338
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.333
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.324
|
Fly |
|
|
positive regulation of hematopoietic stem cell migration
|
GO:2000473 |
1 |
0.316
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.314
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.312
|
Mouse |
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.311
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.311
|
Mouse |
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
52 |
0.309
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
71 |
0.308
|
Mouse |
|
|
cell adhesion
|
GO:0007155 |
329 |
0.305
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.304
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.295
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
56 |
0.291
|
|
|
|
neutrophil chemotaxis
|
GO:0030593 |
36 |
0.291
|
Mouse |
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.285
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.284
|
|
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.284
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.279
|
|
|
|
cd8 positive alpha beta t cell extravasation
|
GO:0035697 |
3 |
0.275
|
|
|
|
regulation of monocyte extravasation
|
GO:2000437 |
2 |
0.274
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
57 |
0.273
|
Mouse |
|
|
neuron migration
|
GO:0001764 |
122 |
0.270
|
Mouse |
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.270
|
Fly |
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.269
|
|
|
|
eosinophil degranulation
|
GO:0043308 |
1 |
0.266
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.265
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.264
|
Fly |
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.263
|
|
|
|
regulation of cd8 positive alpha beta t cell extravasation
|
GO:2000449 |
3 |
0.263
|
|
|
|
t cell extravasation
|
GO:0072683 |
4 |
0.260
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
29 |
0.257
|
|
|
|
positive regulation of neutrophil chemotaxis
|
GO:0090023 |
12 |
0.256
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.253
|
Fly |
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.252
|
|
|
|
regulation of immunological synapse formation
|
GO:2000520 |
2 |
0.251
|
|
|
|
regulation of neutrophil migration
|
GO:1902622 |
14 |
0.251
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.249
|
Fly |
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.249
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.246
|
|
|
|
cell killing
|
GO:0001906 |
67 |
0.240
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.237
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.237
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.237
|
|
|
|
positive regulation of chemotaxis
|
GO:0050921 |
38 |
0.237
|
|
|
|
positive regulation of t cell receptor signaling pathway
|
GO:0050862 |
4 |
0.232
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.230
|
|
|
|
negative regulation of eosinophil degranulation
|
GO:0043310 |
1 |
0.229
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.229
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.229
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.229
|
Mouse |
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
197 |
0.228
|
|
|
|
positive regulation of calcium mediated signaling
|
GO:0050850 |
15 |
0.226
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.226
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.221
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.219
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.219
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.218
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.218
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.214
|
|
|
|
hematopoietic stem cell migration
|
GO:0035701 |
1 |
0.209
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.209
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.208
|
Human Mouse |
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.207
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.205
|
Mouse |
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.199
|
Mouse Fly |
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.197
|
|
|
|
b cell activation involved in immune response
|
GO:0002312 |
50 |
0.195
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.195
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.194
|
Mouse |
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.194
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.192
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.191
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.189
|
Mouse |
|
|
motor neuron axon guidance
|
GO:0008045 |
26 |
0.187
|
|
|
|
regulation of t cell extravasation
|
GO:2000407 |
3 |
0.187
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.187
|
|
|
|
eosinophil activation
|
GO:0043307 |
1 |
0.185
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.185
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.184
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.183
|
Mouse |
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.180
|
|
|
|
positive regulation of dendritic cell chemotaxis
|
GO:2000510 |
1 |
0.180
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter involved in smooth muscle cell differentiation
|
GO:2000721 |
2 |
0.180
|
Mouse |
|
|
negative regulation of nervous system development
|
GO:0051961 |
156 |
0.178
|
Fly |
|
|
t helper 1 type immune response
|
GO:0042088 |
25 |
0.178
|
|
|
|
chemokine mediated signaling pathway
|
GO:0070098 |
17 |
0.177
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.177
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.175
|
Mouse |
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.175
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.175
|
|
|
|
regulation of alpha beta t cell proliferation
|
GO:0046640 |
18 |
0.174
|
|
|
|
positive t cell selection
|
GO:0043368 |
23 |
0.173
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.171
|
Mouse |
|
|
defense response to virus
|
GO:0051607 |
68 |
0.170
|
Mouse |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.170
|
|
|
|
toll like receptor 7 signaling pathway
|
GO:0034154 |
4 |
0.170
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
61 |
0.169
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.169
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
50 |
0.168
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.166
|
|
|
|
positive regulation of immunological synapse formation
|
GO:2000522 |
1 |
0.164
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.163
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.163
|
Mouse |
|
|
t helper 17 cell chemotaxis
|
GO:0035705 |
1 |
0.160
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.159
|
Mouse |
|
|
negative regulation of multi organism process
|
GO:0043901 |
68 |
0.158
|
|
|
|
helper t cell chemotaxis
|
GO:0035704 |
1 |
0.157
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.156
|
|
|
|
interleukin 12 secretion
|
GO:0072610 |
3 |
0.156
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.154
|
|
|
|
positive regulation of t cell costimulation
|
GO:2000525 |
2 |
0.152
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.151
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.151
|
Fly |
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.151
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.150
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.150
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
45 |
0.148
|
|
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.147
|
Mouse |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.145
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.144
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.144
|
Mouse |
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.143
|
Mouse |
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.143
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.143
|
Mouse Fly |
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.142
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.141
|
|
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
39 |
0.139
|
|
|
|
regulation of neutrophil chemotaxis
|
GO:0090022 |
14 |
0.138
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.137
|
Mouse |
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.135
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.132
|
|
|
|
regulation of hematopoietic stem cell migration
|
GO:2000471 |
1 |
0.131
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.126
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
50 |
0.126
|
|
|
|
regulation of dendritic cell chemotaxis
|
GO:2000508 |
1 |
0.126
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.123
|
|
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
41 |
0.123
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.122
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.121
|
Mouse |
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
83 |
0.120
|
|
|
|
regulation of immune complex clearance by monocytes and macrophages
|
GO:0090264 |
2 |
0.120
|
|
|
|
keratinocyte differentiation
|
GO:0030216 |
48 |
0.120
|
|
|
|
extracellular structure organization
|
GO:0043062 |
148 |
0.120
|
Mouse |
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.118
|
|
|
|
calcium ion transport into cytosol
|
GO:0060402 |
48 |
0.118
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.117
|
|
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
43 |
0.117
|
Mouse |
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.117
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
51 |
0.115
|
|
|
|
microglial cell activation involved in immune response
|
GO:0002282 |
1 |
0.114
|
|
|
|
positive regulation of monocyte chemotaxis
|
GO:0090026 |
2 |
0.113
|
|
|
|
bone remodeling
|
GO:0046849 |
53 |
0.113
|
Mouse |
|
|
regulation of dendritic cell apoptotic process
|
GO:2000668 |
3 |
0.112
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.111
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.111
|
|
|
|
positive regulation of granulocyte chemotaxis
|
GO:0071624 |
12 |
0.111
|
|
|
|
alpha beta t cell proliferation
|
GO:0046633 |
21 |
0.110
|
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
50 |
0.109
|
|
|
|
negative regulation of ras protein signal transduction
|
GO:0046580 |
18 |
0.108
|
Mouse |
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.108
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.108
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
83 |
0.108
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.107
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.106
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.106
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
61 |
0.106
|
|
|
|
odontogenesis of dentin containing tooth
|
GO:0042475 |
66 |
0.105
|
Mouse |
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
52 |
0.105
|
|
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
42 |
0.104
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.104
|
Mouse |
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.104
|
|
|
|
bone resorption
|
GO:0045453 |
38 |
0.104
|
Mouse |
|
|
placenta development
|
GO:0001890 |
140 |
0.103
|
Mouse |
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.103
|
|
|
|
telencephalon cell migration
|
GO:0022029 |
55 |
0.102
|
|
|
|
negative regulation of leukocyte mediated immunity
|
GO:0002704 |
29 |
0.102
|
|
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.102
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.101
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
53 |
0.099
|
|
|
|
regulated secretory pathway
|
GO:0045055 |
32 |
0.099
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.098
|
|
|
|
regulation of toll like receptor signaling pathway
|
GO:0034121 |
20 |
0.096
|
|
|
|
gastrulation
|
GO:0007369 |
116 |
0.096
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
55 |
0.096
|
|
|
|
positive regulation of alpha beta t cell activation
|
GO:0046635 |
39 |
0.095
|
|
|
|
immune complex clearance
|
GO:0002434 |
2 |
0.094
|
|
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
61 |
0.094
|
|
|
|
positive regulation of neutrophil migration
|
GO:1902624 |
12 |
0.094
|
|
|
|
natural killer cell activation
|
GO:0030101 |
44 |
0.094
|
|
|
|
interferon beta biosynthetic process
|
GO:0045350 |
4 |
0.093
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.093
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.092
|
|
|
|
leukocyte degranulation
|
GO:0043299 |
27 |
0.092
|
|
|
|
somatic diversification of immune receptors via germline recombination within a single locus
|
GO:0002562 |
51 |
0.092
|
|
|
|
monocyte extravasation
|
GO:0035696 |
2 |
0.091
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.091
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.091
|
Human |
|
|
regulation of eosinophil degranulation
|
GO:0043309 |
1 |
0.090
|
|
|
|
regulation of interleukin 6 production
|
GO:0032675 |
55 |
0.090
|
|
|
|
t cell activation involved in immune response
|
GO:0002286 |
43 |
0.088
|
Human |
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.088
|
Mouse |
|
|
blood coagulation
|
GO:0007596 |
76 |
0.086
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.086
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.086
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.085
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.085
|
|
|
|
eosinophil activation involved in immune response
|
GO:0002278 |
1 |
0.085
|
|
|
|
alpha beta t cell differentiation involved in immune response
|
GO:0002293 |
30 |
0.084
|
|
|
|
regulation of vascular endothelial growth factor production
|
GO:0010574 |
13 |
0.083
|
|
|
|
immune complex clearance by monocytes and macrophages
|
GO:0002436 |
2 |
0.083
|
|
|
|
cell recognition
|
GO:0008037 |
83 |
0.083
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.082
|
Mouse Fly |
|
|
tolerance induction
|
GO:0002507 |
14 |
0.082
|
|
|
|
somatic diversification of immunoglobulins
|
GO:0016445 |
43 |
0.081
|
|
|
|
negative regulation of toll like receptor signaling pathway
|
GO:0034122 |
14 |
0.081
|
|
|
|
post embryonic organ development
|
GO:0048569 |
17 |
0.080
|
Fly |
|
|
interleukin 6 production
|
GO:0032635 |
58 |
0.080
|
|
|
|
isotype switching
|
GO:0045190 |
36 |
0.080
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.080
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.079
|
Fly |
|
|
regulation of t cell receptor signaling pathway
|
GO:0050856 |
21 |
0.079
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.079
|
|
|
|
cerebral cortex cell migration
|
GO:0021795 |
44 |
0.079
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.079
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.079
|
Mouse |
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.078
|
Mouse |
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.078
|
|
|
|
somatic diversification of immunoglobulins involved in immune response
|
GO:0002208 |
36 |
0.078
|
|
|
|
inflammatory response to antigenic stimulus
|
GO:0002437 |
30 |
0.078
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.077
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.077
|
|
|
|
modulation of growth of symbiont involved in interaction with host
|
GO:0044144 |
19 |
0.077
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.077
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.077
|
Mouse |
|
|
cation transport
|
GO:0006812 |
399 |
0.076
|
|
|
|
positive regulation of behavior
|
GO:0048520 |
40 |
0.076
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.075
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
93 |
0.075
|
|
|
|
leukocyte mediated cytotoxicity
|
GO:0001909 |
62 |
0.074
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.074
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.074
|
|
|
|
pallium development
|
GO:0021543 |
120 |
0.073
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
88 |
0.073
|
Mouse |
|
|
cell junction organization
|
GO:0034330 |
77 |
0.073
|
Mouse |
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.073
|
|
|
|
kidney development
|
GO:0001822 |
213 |
0.073
|
Mouse |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.072
|
|
|
|
regulation of inflammatory response to antigenic stimulus
|
GO:0002861 |
21 |
0.072
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.072
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.072
|
|
|
|
negative regulation of type 2 immune response
|
GO:0002829 |
8 |
0.071
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.071
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.070
|
Mouse |
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
89 |
0.070
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.069
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.069
|
|
|
|
regulation of type 2 immune response
|
GO:0002828 |
18 |
0.069
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.069
|
Mouse |
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.069
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.069
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.068
|
|
|
|
cerebral cortex development
|
GO:0021987 |
86 |
0.068
|
|
|
|
negative t cell selection
|
GO:0043383 |
13 |
0.068
|
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.068
|
|
|
|
regulation of growth of symbiont in host
|
GO:0044126 |
19 |
0.068
|
|
|
|
endoderm development
|
GO:0007492 |
45 |
0.068
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.068
|
|
|
|
synapse organization
|
GO:0050808 |
125 |
0.068
|
Fly |
|
|
somatic recombination of immunoglobulin genes involved in immune response
|
GO:0002204 |
36 |
0.067
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.067
|
Mouse |
|
|
cardiac muscle tissue development
|
GO:0048738 |
130 |
0.067
|
|
|
|
eosinophil mediated immunity
|
GO:0002447 |
1 |
0.066
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.066
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.066
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.065
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.065
|
|
|
|
negative regulation of growth of symbiont involved in interaction with host
|
GO:0044146 |
19 |
0.064
|
|
|
|
forebrain cell migration
|
GO:0021885 |
58 |
0.064
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.064
|
Mouse |
|
|
regulation of mast cell proliferation
|
GO:0070666 |
4 |
0.064
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.063
|
|
|
|
microglial cell activation
|
GO:0001774 |
3 |
0.063
|
|
|
|
t cell mediated immunity
|
GO:0002456 |
50 |
0.063
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.063
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.063
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.062
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
81 |
0.062
|
|
|
|
thymic t cell selection
|
GO:0045061 |
22 |
0.062
|
|
|
|
mesodermal cell migration
|
GO:0008078 |
4 |
0.062
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.062
|
|
|
|
cell growth
|
GO:0016049 |
130 |
0.061
|
Fly |
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.060
|
|
|
|
salivary gland development
|
GO:0007431 |
37 |
0.060
|
Fly |
|
|
neural precursor cell proliferation
|
GO:0061351 |
121 |
0.060
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.060
|
|
|
|
cell maturation
|
GO:0048469 |
127 |
0.060
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.060
|
|
|
|
negative regulation of rho protein signal transduction
|
GO:0035024 |
7 |
0.060
|
Mouse |
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
74 |
0.059
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.059
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.058
|
|
|
|
dna recombination
|
GO:0006310 |
92 |
0.058
|
|
|
|
regulation of t helper 1 type immune response
|
GO:0002825 |
17 |
0.058
|
|
|
|
microglia differentiation
|
GO:0014004 |
2 |
0.058
|
Mouse |
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.057
|
|
|
|
natural killer cell mediated immunity
|
GO:0002228 |
29 |
0.057
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.057
|
|
|
|
interleukin 12 production
|
GO:0032615 |
32 |
0.057
|
|
|
|
negative regulation of erk1 and erk2 cascade
|
GO:0070373 |
21 |
0.057
|
|
|
|
regulation of tumor necrosis factor biosynthetic process
|
GO:0042534 |
10 |
0.057
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
65 |
0.056
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.056
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.056
|
|
|
|
segmentation
|
GO:0035282 |
93 |
0.056
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
61 |
0.055
|
|
|
|
b cell mediated immunity
|
GO:0019724 |
71 |
0.055
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.055
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.055
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.055
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.055
|
|
|
|
substrate adhesion dependent cell spreading
|
GO:0034446 |
30 |
0.054
|
|
|
|
alpha beta t cell activation involved in immune response
|
GO:0002287 |
31 |
0.054
|
|
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
86 |
0.054
|
|
|
|
interleukin 1 beta production
|
GO:0032611 |
30 |
0.054
|
|
|
|
positive regulation of myeloid leukocyte differentiation
|
GO:0002763 |
26 |
0.054
|
Mouse |
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.054
|
|
|
|
regulation of leukocyte mediated cytotoxicity
|
GO:0001910 |
38 |
0.053
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
54 |
0.053
|
|
|
|
neutrophil mediated killing of gram positive bacterium
|
GO:0070946 |
2 |
0.053
|
|
|
|
regulation of erythrocyte differentiation
|
GO:0045646 |
23 |
0.053
|
|
|
|
positive regulation of antigen receptor mediated signaling pathway
|
GO:0050857 |
9 |
0.052
|
|
|
|
lipopolysaccharide mediated signaling pathway
|
GO:0031663 |
25 |
0.052
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.052
|
|
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
70 |
0.052
|
|
|
|
calcium mediated signaling
|
GO:0019722 |
46 |
0.052
|
|
|
|
interleukin 2 production
|
GO:0032623 |
33 |
0.051
|
|
|
|
positive regulation of leukocyte mediated cytotoxicity
|
GO:0001912 |
31 |
0.051
|
|
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.051
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
69 |
0.051
|
Mouse |
|
|
female gamete generation
|
GO:0007292 |
74 |
0.051
|
Fly |
|
|
positive regulation of osteoblast proliferation
|
GO:0033690 |
9 |
0.051
|
Mouse |
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.050
|
|
|
|
t cell apoptotic process
|
GO:0070231 |
39 |
0.050
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.050
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.050
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.050
|
|
|
|
toll like receptor signaling pathway
|
GO:0002224 |
38 |
0.049
|
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
77 |
0.049
|
|
|
|
regulation of cell killing
|
GO:0031341 |
40 |
0.049
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
64 |
0.049
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.048
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.048
|
Mouse |
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
51 |
0.048
|
|
|
|
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation
|
GO:2000526 |
1 |
0.048
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
80 |
0.048
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
36 |
0.048
|
|
|
|
mesenchyme development
|
GO:0060485 |
152 |
0.048
|
|
|
|
somatic diversification of immune receptors
|
GO:0002200 |
53 |
0.047
|
|
|
|
mammary gland epithelium development
|
GO:0061180 |
65 |
0.047
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
74 |
0.047
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.047
|
|
|
|
smooth muscle tissue development
|
GO:0048745 |
22 |
0.047
|
Mouse |
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.047
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.046
|
Mouse |
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.046
|
|
|
|
antigen processing and presentation
|
GO:0019882 |
47 |
0.046
|
|
|
|
regulation of calcium mediated signaling
|
GO:0050848 |
19 |
0.046
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.046
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
8 |
0.046
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.045
|
Mouse |
|
|
negative regulation of macrophage apoptotic process
|
GO:2000110 |
3 |
0.045
|
|
|
|
somatic recombination of immunoglobulin gene segments
|
GO:0016447 |
42 |
0.045
|
|
|
|
positive regulation of inflammatory response to antigenic stimulus
|
GO:0002863 |
11 |
0.045
|
|
|
|
myeloid dendritic cell differentiation
|
GO:0043011 |
16 |
0.045
|
|
|
|
acute inflammatory response
|
GO:0002526 |
41 |
0.045
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.045
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
62 |
0.045
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.045
|
|
|
|
t cell differentiation involved in immune response
|
GO:0002292 |
30 |
0.044
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.044
|
|
|
|
production of molecular mediator involved in inflammatory response
|
GO:0002532 |
21 |
0.044
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.044
|
|
|
|
positive regulation of b cell activation
|
GO:0050871 |
49 |
0.043
|
|
|
|
somatic cell dna recombination
|
GO:0016444 |
51 |
0.043
|
|
|
|
regulation of homotypic cell cell adhesion
|
GO:0034110 |
13 |
0.043
|
|
|
|
plasma membrane organization
|
GO:0007009 |
90 |
0.043
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.043
|
|
|
|
growth of symbiont in host
|
GO:0044117 |
23 |
0.043
|
|
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
41 |
0.043
|
|
|
|
notch signaling pathway
|
GO:0007219 |
71 |
0.043
|
|
|
|
cell adhesion mediated by integrin
|
GO:0033627 |
18 |
0.043
|
Mouse |
