|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.919
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.909
|
Mouse |
|
|
positive regulation of neutrophil chemotaxis
|
GO:0090023 |
12 |
0.906
|
|
|
|
regulation of monocyte chemotaxis
|
GO:0090025 |
3 |
0.893
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.892
|
|
|
|
positive regulation of monocyte chemotaxis
|
GO:0090026 |
2 |
0.870
|
|
|
|
mature dendritic cell differentiation
|
GO:0097029 |
3 |
0.835
|
|
|
|
interleukin 12 secretion
|
GO:0072610 |
3 |
0.834
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.815
|
Mouse Fly |
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.813
|
Mouse |
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.792
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.780
|
Mouse |
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.777
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.767
|
Mouse |
|
|
calcium ion transport into cytosol
|
GO:0060402 |
48 |
0.757
|
|
|
|
positive regulation of eosinophil migration
|
GO:2000418 |
2 |
0.742
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.725
|
|
|
|
regulation of neutrophil chemotaxis
|
GO:0090022 |
14 |
0.716
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.711
|
|
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
41 |
0.705
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.699
|
Mouse |
|
|
positive regulation of thymocyte migration
|
GO:2000412 |
2 |
0.694
|
|
|
|
negative regulation of macrophage apoptotic process
|
GO:2000110 |
3 |
0.691
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.656
|
Mouse |
|
|
regulation of antigen processing and presentation
|
GO:0002577 |
10 |
0.652
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.649
|
|
|
|
positive regulation of chemotaxis
|
GO:0050921 |
38 |
0.637
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.635
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.632
|
|
|
|
positive regulation of granulocyte chemotaxis
|
GO:0071624 |
12 |
0.631
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.626
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.621
|
Mouse |
|
|
positive regulation of antigen processing and presentation
|
GO:0002579 |
10 |
0.620
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.616
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.606
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.604
|
Mouse |
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.604
|
|
|
|
antigen processing and presentation
|
GO:0019882 |
47 |
0.604
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.601
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.599
|
|
|
|
positive regulation of neutrophil migration
|
GO:1902624 |
12 |
0.598
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.591
|
Mouse |
|
|
cytosolic calcium ion transport
|
GO:0060401 |
48 |
0.591
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.574
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.573
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.572
|
Mouse Fly |
|
|
action potential
|
GO:0001508 |
78 |
0.571
|
|
|
|
regulation of t cell costimulation
|
GO:2000523 |
2 |
0.567
|
|
|
|
tumor necrosis factor production
|
GO:0032640 |
50 |
0.566
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.557
|
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.554
|
|
|
|
positive regulation of dendritic cell dendrite assembly
|
GO:2000549 |
1 |
0.547
|
|
|
|
positive regulation of cd8 positive alpha beta t cell extravasation
|
GO:2000451 |
2 |
0.543
|
|
|
|
granulocyte chemotaxis
|
GO:0071621 |
39 |
0.542
|
Mouse |
|
|
stimulatory c type lectin receptor signaling pathway
|
GO:0002223 |
2 |
0.541
|
|
|
|
myeloid cell activation involved in immune response
|
GO:0002275 |
34 |
0.539
|
|
|
|
cd4 positive alpha beta t cell cytokine production
|
GO:0035743 |
4 |
0.529
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.529
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.522
|
|
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.517
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.510
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.509
|
|
|
|
sequestering of calcium ion
|
GO:0051208 |
18 |
0.507
|
|
|
|
dendritic cell chemotaxis
|
GO:0002407 |
7 |
0.503
|
|
|
|
regulation of b cell chemotaxis
|
GO:2000537 |
2 |
0.503
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.501
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.496
|
|
|
|
granulocyte migration
|
GO:0097530 |
43 |
0.496
|
Mouse |
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.495
|
Mouse |
|
|
endocytosis
|
GO:0006897 |
168 |
0.494
|
Mouse Fly |
|
|
sequestering of metal ion
|
GO:0051238 |
19 |
0.488
|
|
|
|
regulation of thymocyte migration
|
GO:2000410 |
2 |
0.488
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.486
|
|
|
|
detection of external biotic stimulus
|
GO:0098581 |
9 |
0.485
|
|
|
|
eosinophil migration
|
GO:0072677 |
3 |
0.484
|
|
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.475
|
|
|
|
regulation of eosinophil migration
|
GO:2000416 |
2 |
0.475
|
|
|
|
neutrophil chemotaxis
|
GO:0030593 |
36 |
0.473
|
Mouse |
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.472
|
|
|
|
eosinophil activation
|
GO:0043307 |
1 |
0.470
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.463
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.455
|
Mouse |
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.453
|
|
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
70 |
0.452
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.451
|
Mouse |
|
|
macrophage chemotaxis
|
GO:0048246 |
14 |
0.448
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
64 |
0.437
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.431
|
Mouse |
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
51 |
0.427
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.422
|
|
|
|
negative regulation of eosinophil degranulation
|
GO:0043310 |
1 |
0.418
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.416
|
Mouse |
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.413
|
Mouse |
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.412
|
Mouse |
|
|
thymocyte migration
|
GO:0072679 |
2 |
0.409
|
|
|
|
natural killer cell chemotaxis
|
GO:0035747 |
1 |
0.407
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.405
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.400
|
Mouse |
|
|
mapk cascade
|
GO:0000165 |
281 |
0.398
|
Mouse |
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.397
|
Mouse |
|
|
positive regulation of t cell extravasation
|
GO:2000409 |
2 |
0.391
|
|
|
|
release of sequestered calcium ion into cytosol
|
GO:0051209 |
42 |
0.391
|
|
|
|
positive regulation of t cell costimulation
|
GO:2000525 |
2 |
0.390
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
61 |
0.387
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.386
|
|
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.386
|
|
|
|
positive regulation of natural killer cell chemotaxis
|
GO:2000503 |
1 |
0.382
|
|
|
|
thymic t cell selection
|
GO:0045061 |
22 |
0.375
|
|
|
|
negative thymic t cell selection
|
GO:0045060 |
12 |
0.372
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.371
|
|
|
|
positive regulation of dendritic cell chemotaxis
|
GO:2000510 |
1 |
0.370
|
|
|
|
positive regulation of immunological synapse formation
|
GO:2000522 |
1 |
0.359
|
|
|
|
chemokine mediated signaling pathway
|
GO:0070098 |
17 |
0.358
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.355
|
|
|
|
helper t cell chemotaxis
|
GO:0035704 |
1 |
0.350
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.346
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.341
|
|
|
|
cd8 positive alpha beta t cell extravasation
|
GO:0035697 |
3 |
0.339
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.330
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.326
|
Human Mouse |
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.325
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.322
|
Mouse |
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.316
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.314
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.314
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
57 |
0.313
|
Mouse |
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.309
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.309
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.308
|
|
|
|
interleukin 1 production
|
GO:0032612 |
31 |
0.305
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.305
|
|
|
|
positive regulation of monocyte extravasation
|
GO:2000439 |
1 |
0.301
|
|
|
|
cell surface pattern recognition receptor signaling pathway
|
GO:0002752 |
2 |
0.301
|
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
52 |
0.300
|
|
|
|
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation
|
GO:2000526 |
1 |
0.300
|
|
|
|
humoral immune response
|
GO:0006959 |
57 |
0.292
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.290
|
Mouse |
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
50 |
0.286
|
|
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
52 |
0.286
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.284
|
|
|
|
regulation of dendritic cell dendrite assembly
|
GO:2000547 |
2 |
0.284
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.283
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.283
|
Mouse |
|
|
positive regulation of t cell receptor signaling pathway
|
GO:0050862 |
4 |
0.279
|
|
|
|
regulation of alpha beta t cell proliferation
|
GO:0046640 |
18 |
0.277
|
|
|
|
dendritic cell dendrite assembly
|
GO:0097026 |
2 |
0.277
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.276
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.276
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.276
|
Mouse |
|
|
t helper 17 cell chemotaxis
|
GO:0035705 |
1 |
0.273
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
53 |
0.272
|
|
|
|
regulation of granulocyte chemotaxis
|
GO:0071622 |
17 |
0.271
|
|
|
|
regulation of immune complex clearance by monocytes and macrophages
|
GO:0090264 |
2 |
0.270
|
|
|
|
positive regulation of hematopoietic stem cell migration
|
GO:2000473 |
1 |
0.269
|
|
|
|
eosinophil activation involved in immune response
|
GO:0002278 |
1 |
0.269
|
|
|
|
detection of yeast
|
GO:0001879 |
2 |
0.266
|
|
|
|
positive regulation of lymphocyte migration
|
GO:2000403 |
11 |
0.265
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.265
|
Mouse |
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.264
|
Mouse |
|
|
t helper 1 cell cytokine production
|
GO:0035744 |
1 |
0.263
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.262
|
Human Mouse Fly |
|
|
regulation of neutrophil migration
|
GO:1902622 |
14 |
0.262
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.260
|
|
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.257
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.255
|
Mouse |
|
|
t cell mediated immunity
|
GO:0002456 |
50 |
0.254
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.252
|
|
|
|
activation of innate immune response
|
GO:0002218 |
56 |
0.248
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
61 |
0.247
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.247
|
|
|
|
monocyte extravasation
|
GO:0035696 |
2 |
0.246
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.244
|
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.243
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.242
|
|
|
|
serotonin secretion by mast cell
|
GO:0002552 |
1 |
0.238
|
|
|
|
regulation of monocyte extravasation
|
GO:2000437 |
2 |
0.238
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.236
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.235
|
Mouse |
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.233
|
|
|
|
cdc42 protein signal transduction
|
GO:0032488 |
0 |
0.231
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.231
|
Mouse |
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.230
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.229
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.229
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.227
|
|
|
|
response to molecule of fungal origin
|
GO:0002238 |
4 |
0.225
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.225
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.225
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.224
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.224
|
|
|
|
t helper 1 type immune response
|
GO:0042088 |
25 |
0.223
|
|
|
|
regulation of t helper 1 type immune response
|
GO:0002825 |
17 |
0.222
|
|
|
|
regulation of natural killer cell chemotaxis
|
GO:2000501 |
1 |
0.221
|
|
|
|
positive regulation of t helper 2 cell cytokine production
|
GO:2000553 |
3 |
0.221
|
|
|
|
interleukin 1 beta production
|
GO:0032611 |
30 |
0.220
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
29 |
0.220
|
|
|
|
positive regulation of b cell chemotaxis
|
GO:2000538 |
2 |
0.220
|
|
|
|
positive regulation of immunoglobulin production in mucosal tissue
|
GO:2000558 |
1 |
0.216
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.216
|
|
|
|
neutrophil migration
|
GO:1990266 |
37 |
0.215
|
Mouse |
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.214
|
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.210
|
|
|
|
positive regulation of behavior
|
GO:0048520 |
40 |
0.210
|
|
|
|
t cell extravasation
|
GO:0072683 |
4 |
0.209
|
|
|
|
positive regulation of cd4 positive alpha beta t cell proliferation
|
GO:2000563 |
1 |
0.208
|
|
|
|
regulation of t helper 2 cell cytokine production
|
GO:2000551 |
3 |
0.207
|
|
|
|
regulation of immunological synapse formation
|
GO:2000520 |
2 |
0.207
|
|
|
|
regulation of type 2 immune response
|
GO:0002828 |
18 |
0.205
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.205
|
|
|
|
positive regulation of alpha beta t cell activation
|
GO:0046635 |
39 |
0.204
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
50 |
0.202
|
|
|
|
positive regulation of inflammatory response
|
GO:0050729 |
47 |
0.202
|
|
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.199
|
|
|
|
hematopoietic stem cell migration
|
GO:0035701 |
1 |
0.199
|
|
|
|
lymphocyte chemotaxis
|
GO:0048247 |
10 |
0.198
|
|
|
|
immune complex clearance
|
GO:0002434 |
2 |
0.195
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.194
|
Mouse |
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.193
|
|
|
|
positive regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903557 |
31 |
0.193
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.192
|
|
|
|
calcium mediated signaling
|
GO:0019722 |
46 |
0.190
|
Mouse |
|
|
t cell activation involved in immune response
|
GO:0002286 |
43 |
0.189
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.187
|
|
|
|
regulation of calcium ion transport
|
GO:0051924 |
69 |
0.186
|
|
|
|
positive regulation of lymphocyte differentiation
|
GO:0045621 |
61 |
0.185
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.183
|
Mouse |
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.180
|
Mouse |
|
|
positive regulation of ion transport
|
GO:0043270 |
65 |
0.179
|
|
|
|
regulation of myeloid cell apoptotic process
|
GO:0033032 |
19 |
0.177
|
|
|
|
lymphocyte migration
|
GO:0072676 |
26 |
0.177
|
Mouse |
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.177
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.175
|
|
|
|
leukocyte degranulation
|
GO:0043299 |
27 |
0.174
|
|
|
|
dendritic cell migration
|
GO:0036336 |
12 |
0.173
|
|
|
|
microglial cell activation involved in immune response
|
GO:0002282 |
1 |
0.172
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.169
|
|
|
|
innate immune response activating cell surface receptor signaling pathway
|
GO:0002220 |
4 |
0.169
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.167
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.166
|
|
|
|
regulation of dendritic cell antigen processing and presentation
|
GO:0002604 |
7 |
0.164
|
|
|
|
regulation of cd8 positive alpha beta t cell extravasation
|
GO:2000449 |
3 |
0.163
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
52 |
0.162
|
Mouse |
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.161
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.161
|
|
|
|
defense response to gram positive bacterium
|
GO:0050830 |
50 |
0.161
|
|
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.161
|
Mouse |
|
|
dendritic cell differentiation
|
GO:0097028 |
26 |
0.159
|
|
|
|
regulation of cell shape
|
GO:0008360 |
39 |
0.159
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.158
|
Mouse |
|
|
positive regulation of interleukin 12 production
|
GO:0032735 |
21 |
0.157
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.156
|
Mouse |
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.155
|
|
|
|
negative regulation of exocytosis
|
GO:0045920 |
12 |
0.155
|
|
|
|
detection of biotic stimulus
|
GO:0009595 |
10 |
0.154
|
|
|
|
mature natural killer cell chemotaxis
|
GO:0035782 |
1 |
0.153
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.152
|
|
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.152
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.150
|
Mouse Fly |
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
2 |
0.150
|
|
|
|
positive regulation of t helper 1 cell differentiation
|
GO:0045627 |
4 |
0.150
|
|
|
|
regulation of toll like receptor 4 signaling pathway
|
GO:0034143 |
4 |
0.149
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.148
|
Mouse |
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.148
|
|
|
|
positive regulation of tumor necrosis factor production
|
GO:0032760 |
30 |
0.147
|
|
|
|
detection of stimulus
|
GO:0051606 |
84 |
0.147
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
80 |
0.147
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
61 |
0.146
|
|
|
|
t cell chemotaxis
|
GO:0010818 |
6 |
0.145
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.145
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.145
|
|
|
|
regulation of dendritic cell chemotaxis
|
GO:2000508 |
1 |
0.145
|
|
|
|
astrocyte cell migration
|
GO:0043615 |
3 |
0.144
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.142
|
|
|
|
positive regulation of type 2 immune response
|
GO:0002830 |
9 |
0.142
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.141
|
|
|
|
regulation of t cell mediated immunity
|
GO:0002709 |
34 |
0.141
|
|
|
|
negative t cell selection
|
GO:0043383 |
13 |
0.141
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.140
|
|
|
|
regulation of t cell extravasation
|
GO:2000407 |
3 |
0.140
|
|
|
|
positive regulation of natural killer cell mediated cytotoxicity
|
GO:0045954 |
16 |
0.139
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.138
|
|
|
|
alpha beta t cell proliferation
|
GO:0046633 |
21 |
0.138
|
|
|
|
t cell migration
|
GO:0072678 |
19 |
0.138
|
Mouse |
|
|
single organismal cell cell adhesion
|
GO:0016337 |
131 |
0.137
|
Human Mouse |
|
|
cellular extravasation
|
GO:0045123 |
17 |
0.136
|
Mouse |
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.136
|
|
|
|
cd4 positive alpha beta t cell proliferation
|
GO:0035739 |
2 |
0.136
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
47 |
0.135
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.135
|
Mouse |
|
|
wound healing
|
GO:0042060 |
157 |
0.135
|
Fly |
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.134
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.134
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
0 |
0.133
|
|
|
|
positive regulation of t helper 1 type immune response
|
GO:0002827 |
12 |
0.132
|
|
|
|
myeloid leukocyte mediated immunity
|
GO:0002444 |
42 |
0.131
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
49 |
0.131
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.131
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.130
|
|
|
|
positive regulation of natural killer cell mediated immunity
|
GO:0002717 |
16 |
0.129
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.127
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
138 |
0.127
|
Fly |
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.127
|
|
|
|
eosinophil degranulation
|
GO:0043308 |
1 |
0.126
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.125
|
Fly |
|
|
regulation of exocytosis
|
GO:0017157 |
61 |
0.125
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.125
|
|
|
|
cell recognition
|
GO:0008037 |
83 |
0.123
|
|
|
|
regulated secretory pathway
|
GO:0045055 |
32 |
0.123
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.123
|
Mouse |
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
65 |
0.121
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.121
|
Mouse |
|
|
t cell selection
|
GO:0045058 |
34 |
0.119
|
|
|
|
regulation of eosinophil degranulation
|
GO:0043309 |
1 |
0.119
|
|
|
|
positive regulation of glycoprotein metabolic process
|
GO:1903020 |
6 |
0.119
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.119
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
268 |
0.119
|
|
|
|
cell killing
|
GO:0001906 |
67 |
0.118
|
|
|
|
b cell chemotaxis
|
GO:0035754 |
3 |
0.118
|
|
|
|
t helper 2 cell cytokine production
|
GO:0035745 |
4 |
0.117
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.116
|
|
|
|
positive regulation of antigen receptor mediated signaling pathway
|
GO:0050857 |
9 |
0.115
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.113
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
69 |
0.113
|
Mouse |
|
|
positive regulation of interferon gamma production
|
GO:0032729 |
39 |
0.112
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
55 |
0.111
|
Mouse |
|
|
t cell costimulation
|
GO:0031295 |
14 |
0.110
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.110
|
|
|
|
regulation of immunoglobulin production in mucosal tissue
|
GO:2000557 |
1 |
0.109
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.109
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.109
|
Mouse |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.108
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.108
|
|
|
|
regulation of regulated secretory pathway
|
GO:1903305 |
20 |
0.108
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
55 |
0.107
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.107
|
Mouse |
|
|
regulation of phospholipase c activity
|
GO:1900274 |
3 |
0.107
|
|
|
|
granulocyte activation
|
GO:0036230 |
10 |
0.106
|
|
|
|
positive regulation of alpha beta t cell proliferation
|
GO:0046641 |
12 |
0.106
|
|
|
|
lymphocyte costimulation
|
GO:0031294 |
15 |
0.106
|
|
|
|
regulation of cd4 positive alpha beta t cell proliferation
|
GO:2000561 |
2 |
0.106
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.105
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.105
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.104
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.104
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.104
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
68 |
0.104
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.103
|
|
|
|
organ or tissue specific immune response
|
GO:0002251 |
13 |
0.103
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.103
|
|
|
|
cytokine production involved in immune response
|
GO:0002367 |
34 |
0.102
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.102
|
|
|
|
interferon gamma production
|
GO:0032609 |
67 |
0.102
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.101
|
|
|
|
type 2 immune response
|
GO:0042092 |
23 |
0.100
|
|
|
|
positive regulation of t helper 1 cell cytokine production
|
GO:2000556 |
1 |
0.100
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.099
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.099
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.099
|
|
|
|
immune complex clearance by monocytes and macrophages
|
GO:0002436 |
2 |
0.097
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.097
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.096
|
|
|
|
positive regulation of response to wounding
|
GO:1903036 |
66 |
0.096
|
|
|
|
regulation of cell killing
|
GO:0031341 |
40 |
0.096
|
|
|
|
regulation of hematopoietic stem cell migration
|
GO:2000471 |
1 |
0.095
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.095
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.095
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
68 |
0.094
|
|
|
|
positive regulation of endocytosis
|
GO:0045807 |
42 |
0.094
|
|
|
|
positive regulation of phospholipase activity
|
GO:0010518 |
3 |
0.094
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.094
|
Mouse |
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.094
|
|
|
|
positive regulation of phagocytosis
|
GO:0050766 |
26 |
0.094
|
|
|
|
tolerance induction
|
GO:0002507 |
14 |
0.093
|
|
|
|
germ cell development
|
GO:0007281 |
185 |
0.093
|
Fly |
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
61 |
0.092
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.092
|
Mouse |
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.092
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
58 |
0.092
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.091
|
|
|
|
toll like receptor signaling pathway
|
GO:0002224 |
38 |
0.091
|
|
|
|
immunoglobulin production in mucosal tissue
|
GO:0002426 |
3 |
0.091
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.090
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.090
|
Mouse |
|
|
ensheathment of neurons
|
GO:0007272 |
76 |
0.088
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.087
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.087
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.086
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
51 |
0.086
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.086
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.086
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.085
|
|
|
|
detection of fungus
|
GO:0016046 |
2 |
0.085
|
|
|
|
positive regulation of immune complex clearance by monocytes and macrophages
|
GO:0090265 |
2 |
0.084
|
|
|
|
positive regulation of lymphocyte mediated immunity
|
GO:0002708 |
62 |
0.084
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
68 |
0.084
|
|
|
|
interleukin 1 beta secretion
|
GO:0050702 |
16 |
0.084
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.083
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.083
|
|
|
|
eosinophil mediated immunity
|
GO:0002447 |
1 |
0.083
|
|
|
|
negative regulation of myeloid leukocyte mediated immunity
|
GO:0002887 |
7 |
0.082
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
85 |
0.082
|
|
|
|
positive regulation of alpha beta t cell differentiation
|
GO:0046638 |
28 |
0.082
|
|
|
|
microglial cell activation
|
GO:0001774 |
3 |
0.082
|
|
|
|
positive regulation of angiogenesis
|
GO:0045766 |
46 |
0.082
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.082
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
89 |
0.082
|
|
|
|
response to interferon gamma
|
GO:0034341 |
34 |
0.081
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.081
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.081
|
|
|
|
branching involved in mammary gland duct morphogenesis
|
GO:0060444 |
27 |
0.081
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.080
|
|
|
|
negative regulation of leukocyte mediated immunity
|
GO:0002704 |
29 |
0.080
|
|
|
|
regulation of b cell proliferation
|
GO:0030888 |
39 |
0.079
|
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
64 |
0.079
|
Mouse |
|
|
interleukin 12 production
|
GO:0032615 |
32 |
0.079
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.079
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.079
|
|
|
|
t helper cell differentiation
|
GO:0042093 |
28 |
0.079
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.079
|
|
|
|
sensory perception of pain
|
GO:0019233 |
47 |
0.078
|
|
|
|
regulation of lymphocyte migration
|
GO:2000401 |
14 |
0.078
|
|
|
|
cell cell recognition
|
GO:0009988 |
44 |
0.078
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.077
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.077
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.077
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.077
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.076
|
|
|
|
regulation of natural killer cell mediated immunity
|
GO:0002715 |
19 |
0.076
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.076
|
|
|
|
fc receptor mediated inhibitory signaling pathway
|
GO:0002774 |
1 |
0.076
|
|
|
|
positive regulation of gliogenesis
|
GO:0014015 |
27 |
0.075
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.075
|
Mouse |
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.074
|
|
|
|
dendritic cell antigen processing and presentation
|
GO:0002468 |
7 |
0.074
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
56 |
0.073
|
|
|
|
cellular response to molecule of fungal origin
|
GO:0071226 |
2 |
0.073
|
|
|
|
regulation of cytokine production involved in immune response
|
GO:0002718 |
26 |
0.073
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.073
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.073
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.073
|
|
|
|
positive regulation of dendritic cell antigen processing and presentation
|
GO:0002606 |
7 |
0.072
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.072
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.072
|
|
|
|
phagocytosis
|
GO:0006909 |
66 |
0.071
|
Mouse Fly |
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.071
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.070
|
|
|
|
regulation of acute inflammatory response
|
GO:0002673 |
27 |
0.070
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.070
|
|
|
|
positive regulation of phospholipase c activity
|
GO:0010863 |
2 |
0.070
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.070
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
55 |
0.069
|
Mouse |
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
40 |
0.069
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.068
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.068
|
|
|
|
negative regulation of secretion by cell
|
GO:1903531 |
54 |
0.068
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.068
|
Mouse |
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.066
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.066
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
71 |
0.066
|
Mouse |
|
|
axonogenesis
|
GO:0007409 |
274 |
0.066
|
Fly |
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.066
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.065
|
|
|
|
immunoglobulin transcytosis in epithelial cells
|
GO:0002414 |
2 |
0.065
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.064
|
|
|
|
purinergic nucleotide receptor signaling pathway
|
GO:0035590 |
3 |
0.064
|
|
|
|
positive regulation of t cell mediated immunity
|
GO:0002711 |
24 |
0.064
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.063
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.063
|
|
|
|
inflammatory cell apoptotic process
|
GO:0006925 |
11 |
0.062
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.062
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.062
|
Mouse |
|
|
cell maturation
|
GO:0048469 |
127 |
0.062
|
|
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
40 |
0.062
|
|
|
|
immunoglobulin production involved in immunoglobulin mediated immune response
|
GO:0002381 |
43 |
0.062
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.061
|
|
|
|
myeloid cell apoptotic process
|
GO:0033028 |
22 |
0.061
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.060
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.060
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
62 |
0.059
|
Mouse |
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.059
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.059
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
41 |
0.059
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
59 |
0.059
|
Fly |
|
|
regulation of interferon gamma production
|
GO:0032649 |
57 |
0.059
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.058
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.058
|
|
|
|
natural killer cell mediated cytotoxicity
|
GO:0042267 |
29 |
0.058
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
88 |
0.058
|
Mouse |
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.057
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.057
|
|
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
41 |
0.057
|
|
|
|
regulation of leukocyte degranulation
|
GO:0043300 |
20 |
0.056
|
|
