Mus musculus

178 known processes

Itgb1

integrin beta 1 (fibronectin receptor beta)

(Aliases: AA409975,CD29,AA960159,Fnrb,gpIIa,4633401G24Rik)

Itgb1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell adhesion GO:0007155 329 1.000
gliogenesis GO:0042063 141 0.999
cell adhesion mediated by integrin GO:0033627 18 0.999
Human
regulation of transcription from rna polymerase ii promoter in response to hypoxia GO:0061418 2 0.999
urogenital system development GO:0001655 261 0.998
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.998
positive regulation of glial cell proliferation GO:0060252 4 0.998
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.998
axonogenesis GO:0007409 274 0.998
kidney development GO:0001822 213 0.997
metanephric glomerular mesangium development GO:0072223 3 0.997
extrinsic apoptotic signaling pathway GO:0097191 126 0.995
positive regulation of nervous system development GO:0051962 221 0.995
Rat
single organismal cell cell adhesion GO:0016337 131 0.995
Human Mouse
regulation of cell adhesion mediated by integrin GO:0033628 13 0.994
actin filament organization GO:0007015 113 0.993
Mouse Fly
embryonic placenta development GO:0001892 98 0.993
regulation of t cell proliferation GO:0042129 92 0.992
cell substrate adhesion GO:0031589 130 0.992
muscle tissue development GO:0060537 308 0.992
leukocyte proliferation GO:0070661 172 0.992
Mouse
negative regulation of cell proliferation GO:0008285 296 0.992
Rat
skeletal muscle organ development GO:0060538 163 0.991
Fly
protein catabolic process GO:0030163 221 0.991
Worm
ameboidal type cell migration GO:0001667 128 0.990
embryonic organ morphogenesis GO:0048562 276 0.990
gland development GO:0048732 330 0.989
Fly
cellular ketone metabolic process GO:0042180 84 0.989
positive regulation of bmp signaling pathway GO:0030513 23 0.989
substrate adhesion dependent cell spreading GO:0034446 30 0.989
regulation of cytoskeleton organization GO:0051493 122 0.987
Fly
striated muscle tissue development GO:0014706 293 0.987
positive regulation of osteoblast proliferation GO:0033690 9 0.987
Mouse
cation transport GO:0006812 399 0.986
oocyte axis specification GO:0007309 2 0.986
axon guidance GO:0007411 141 0.985
Fly
germ cell development GO:0007281 185 0.985
Fly
cardiac endothelial cell differentiation GO:0003348 4 0.985
membrane invagination GO:0010324 17 0.985
regulation of bmp signaling pathway GO:0030510 60 0.984
mesonephric tubule development GO:0072164 94 0.983
microtubule based process GO:0007017 236 0.983
negative regulation of t cell proliferation GO:0042130 38 0.982
regulation of wound healing GO:0061041 40 0.981
regulation of cell adhesion GO:0030155 154 0.980
Rat
positive regulation of transcription from rna polymerase ii promoter involved in smooth muscle cell differentiation GO:2000721 2 0.979
positive regulation of apoptotic process involved in mammary gland involution GO:0060058 4 0.978
glial cell differentiation GO:0010001 131 0.978
muscle cell differentiation GO:0042692 261 0.976
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 34 0.975
t cell activation GO:0042110 289 0.972
Mouse
positive regulation of cell development GO:0010720 237 0.970
Rat
negative regulation of protein phosphorylation GO:0001933 126 0.970
positive regulation of map kinase activity GO:0043406 84 0.970
regulation of lymphocyte proliferation GO:0050670 117 0.969
integrin mediated signaling pathway GO:0007229 27 0.967
Human Mouse Rat
regulation of apoptotic signaling pathway GO:2001233 197 0.967
glial cell apoptotic process GO:0034349 3 0.967
release of cytochrome c from mitochondria GO:0001836 23 0.967
spermatogenesis GO:0007283 284 0.966
regulation of protein kinase activity GO:0045859 232 0.964
regulation of gliogenesis GO:0014013 50 0.964
regulation of ras protein signal transduction GO:0046578 114 0.962
regulation of protein targeting GO:1903533 61 0.962
microtubule cytoskeleton organization GO:0000226 157 0.961
signal transduction in absence of ligand GO:0038034 55 0.961
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.961
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.959
erbb signaling pathway GO:0038127 32 0.959
response to growth factor GO:0070848 198 0.957
Mouse Rat
neuron projection guidance GO:0097485 141 0.956
Fly
membrane organization GO:0061024 245 0.955
Human Rat
heart trabecula formation GO:0060347 14 0.953
bmp signaling pathway GO:0030509 93 0.953
oocyte construction GO:0007308 2 0.952
platelet aggregation GO:0070527 20 0.951
female gamete generation GO:0007292 74 0.949
Fly
negative regulation of epithelial cell proliferation GO:0050680 64 0.948
apoptotic signaling pathway GO:0097190 306 0.946
blood vessel endothelial cell migration GO:0043534 23 0.945
positive regulation of transcription from rna polymerase ii promoter in response to stress GO:0036003 3 0.945
muscle cell proliferation GO:0033002 52 0.945
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902043 13 0.944
sprouting angiogenesis GO:0002040 26 0.941
ovulation GO:0030728 15 0.940
regulation of kinase activity GO:0043549 249 0.939
cellular response to growth factor stimulus GO:0071363 197 0.939
Mouse
endocytosis GO:0006897 168 0.938
Rat
cardiac muscle tissue morphogenesis GO:0055008 44 0.938
dendrite development GO:0016358 115 0.938
positive regulation of neuron differentiation GO:0045666 141 0.937
Rat
forebrain development GO:0030900 302 0.937
cardiac right ventricle formation GO:0003219 3 0.937
regulation of epithelial cell proliferation GO:0050678 141 0.935
positive regulation of cell death GO:0010942 224 0.935
Human
negative regulation of cell migration GO:0030336 59 0.934
Fly
negative regulation of immature t cell proliferation GO:0033087 3 0.933
regulation of cell cycle GO:0051726 281 0.930
metanephric glomerular mesangial cell proliferation involved in metanephros development GO:0072262 3 0.930
regulation of cell motility GO:2000145 236 0.929
Mouse Rat Fly
negative regulation of apoptotic signaling pathway GO:2001234 104 0.928
morphogenesis of a branching epithelium GO:0061138 193 0.927
muscle cell development GO:0055001 133 0.926
regulation of engulfment of apoptotic cell GO:1901074 2 0.926
cell type specific apoptotic process GO:0097285 268 0.926
regulation of cardiac muscle cell proliferation GO:0060043 23 0.925
gonad development GO:0008406 141 0.924
development of primary sexual characteristics GO:0045137 143 0.924
schwann cell development GO:0014044 22 0.924
divalent inorganic cation transport GO:0072511 178 0.922
regulation of dna templated transcription in response to stress GO:0043620 9 0.922
negative regulation of glial cell proliferation GO:0060253 4 0.922
cell matrix adhesion GO:0007160 68 0.920
immune effector process GO:0002252 321 0.916
myelination in peripheral nervous system GO:0022011 19 0.916
regulation of leukocyte differentiation GO:1902105 159 0.913
oocyte differentiation GO:0009994 35 0.909
regulation of leukocyte proliferation GO:0070663 121 0.907
heart trabecula morphogenesis GO:0061384 26 0.906
neuron maturation GO:0042551 29 0.901
cardiac muscle tissue growth GO:0055017 37 0.900
macromolecule catabolic process GO:0009057 281 0.899
Worm
chemotaxis GO:0006935 247 0.897
Mouse Fly
purine nucleotide metabolic process GO:0006163 302 0.896
regionalization GO:0003002 337 0.894
leukocyte cell cell adhesion GO:0007159 14 0.893
Human
oligodendrocyte differentiation GO:0048709 53 0.892
schwann cell differentiation GO:0014037 26 0.890
rho protein signal transduction GO:0007266 32 0.890
nucleoside phosphate metabolic process GO:0006753 338 0.890
positive regulation of growth GO:0045927 104 0.888
ribonucleotide metabolic process GO:0009259 291 0.888
positive regulation of neuron projection development GO:0010976 79 0.886
Rat
single organism cell adhesion GO:0098602 156 0.886
Human Mouse
positive regulation of kinase activity GO:0033674 155 0.884
microglia development GO:0014005 2 0.884
regulation of endothelial cell chemotaxis GO:2001026 1 0.881
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 8 0.879
regeneration GO:0031099 38 0.878
regulation of cell migration involved in sprouting angiogenesis GO:0090049 4 0.878
tissue migration GO:0090130 68 0.876
negative regulation of cell cycle GO:0045786 123 0.874
striated muscle myosin thick filament assembly GO:0071688 1 0.872
carbon catabolite activation of transcription GO:0045991 4 0.872
neural crest cell migration GO:0001755 32 0.870
dendritic spine maintenance GO:0097062 4 0.869
endothelium development GO:0003158 45 0.865
regulation of jak stat cascade GO:0046425 34 0.865
epidermal growth factor receptor signaling pathway GO:0007173 28 0.864
jak stat cascade GO:0007259 42 0.864
kidney epithelium development GO:0072073 121 0.863
activation of cysteine type endopeptidase activity GO:0097202 27 0.862
t cell proliferation GO:0042098 120 0.860
Mouse
digestive system development GO:0055123 200 0.859
Human Zebrafish Fly
hindbrain development GO:0030902 128 0.859
epithelial tube morphogenesis GO:0060562 303 0.853
mesenchyme development GO:0060485 152 0.853
branching morphogenesis of an epithelial tube GO:0048754 159 0.852
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.852
positive regulation of axon extension GO:0045773 20 0.852
regulation of cellular ketone metabolic process GO:0010565 66 0.850
negative regulation of leukocyte proliferation GO:0070664 46 0.850
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.849
regulation of organ growth GO:0046620 61 0.845
negative regulation of release of cytochrome c from mitochondria GO:0090201 6 0.842
microtubule polymerization or depolymerization GO:0031109 26 0.842
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902042 11 0.841
defense response to other organism GO:0098542 197 0.841
endothelial cell differentiation GO:0045446 41 0.840
lymphocyte differentiation GO:0030098 242 0.839
positive regulation of protein kinase activity GO:0045860 144 0.836
establishment or maintenance of cell polarity GO:0007163 86 0.835
lymphocyte proliferation GO:0046651 164 0.833
Mouse
platelet derived growth factor receptor signaling pathway GO:0048008 32 0.833
photoreceptor cell differentiation GO:0046530 52 0.832
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 4 0.831
cell chemotaxis GO:0060326 81 0.831
Mouse
dendritic spine organization GO:0097061 26 0.830
extracellular structure organization GO:0043062 148 0.828
oogenesis GO:0048477 56 0.825
Fly
glial cell proliferation GO:0014009 10 0.823
negative regulation of bmp signaling pathway GO:0030514 35 0.821
peptidyl tyrosine modification GO:0018212 145 0.819
Rat
engulfment of apoptotic cell GO:0043652 3 0.814
regulation of protein serine threonine kinase activity GO:0071900 157 0.813
morphogenesis of a polarized epithelium GO:0001738 37 0.813
s shaped body morphogenesis GO:0072050 6 0.810
male gamete generation GO:0048232 285 0.810
response to peptide hormone GO:0043434 127 0.810
synapse organization GO:0050808 125 0.808
canonical wnt signaling pathway involved in heart development GO:0061316 3 0.807
wound healing GO:0042060 157 0.807
regulation of cardiac muscle tissue development GO:0055024 31 0.807
regulation of cellular response to hypoxia GO:1900037 2 0.805
renal tubule morphogenesis GO:0061333 72 0.803
ventricular trabecula myocardium morphogenesis GO:0003222 11 0.803
body morphogenesis GO:0010171 45 0.802
Worm
ribose phosphate metabolic process GO:0019693 291 0.802
regulation of neuron projection development GO:0010975 169 0.802
Rat
neuron migration GO:0001764 122 0.801
extracellular matrix organization GO:0030198 147 0.801
glomerular epithelial cell development GO:0072310 6 0.799
regulation of cardiac cell fate specification GO:2000043 1 0.799
sensory organ morphogenesis GO:0090596 242 0.799
negative regulation of ubiquitin protein transferase activity GO:0051444 3 0.799
nephron tubule development GO:0072080 84 0.796
positive regulation of cell proliferation involved in heart valve morphogenesis GO:0003251 1 0.795
positive regulation of apoptotic signaling pathway GO:2001235 95 0.793
negative regulation of rho protein signal transduction GO:0035024 7 0.792
striated muscle cell proliferation GO:0014855 39 0.791
positive regulation of programmed cell death GO:0043068 218 0.789
Human
neuron apoptotic process GO:0051402 142 0.786
purine containing compound metabolic process GO:0072521 311 0.783
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 34 0.782
pallium development GO:0021543 120 0.780
regulation of cellular amine metabolic process GO:0033238 20 0.780
myotube differentiation GO:0014902 105 0.778
negative regulation of lymphocyte apoptotic process GO:0070229 24 0.778
regulation of homeostatic process GO:0032844 182 0.777
regulation of heart growth GO:0060420 31 0.776
morphogenesis of a branching structure GO:0001763 203 0.776
myosin filament organization GO:0031033 3 0.773
connective tissue development GO:0061448 179 0.770
positive regulation of dendrite development GO:1900006 21 0.767
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.765
Rat
regulation of astrocyte differentiation GO:0048710 20 0.763
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 34 0.763
organ growth GO:0035265 117 0.758
small gtpase mediated signal transduction GO:0007264 97 0.757
heart morphogenesis GO:0003007 178 0.757
tyrosine phosphorylation of stat5 protein GO:0042506 9 0.756
filopodium assembly GO:0046847 19 0.753
Mouse
astrocyte differentiation GO:0048708 43 0.753
apoptotic process involved in mammary gland involution GO:0060057 4 0.752
response to radiation GO:0009314 165 0.747
regulation of stat protein import into nucleus GO:2000364 2 0.747
metanephric mesangial cell differentiation GO:0072209 1 0.746
ear development GO:0043583 200 0.743
substrate dependent cell migration GO:0006929 18 0.742
Fly
ras protein signal transduction GO:0007265 77 0.739
outflow tract morphogenesis GO:0003151 53 0.739
regulation of transferase activity GO:0051338 263 0.738
cell migration involved in coronary angiogenesis GO:0060981 1 0.738
microglia differentiation GO:0014004 2 0.738
positive regulation of cell growth GO:0030307 33 0.737
glomerular epithelium development GO:0072010 11 0.737
cellular ion homeostasis GO:0006873 165 0.734
Rat
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 16 0.732
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 31 0.732
blood coagulation GO:0007596 76 0.732
regulation of synapse assembly GO:0051963 29 0.731
organelle assembly GO:0070925 177 0.728
granulocyte migration GO:0097530 43 0.728
Mouse
myofibril assembly GO:0030239 34 0.728
myosin filament assembly GO:0031034 2 0.724
regulation of cardiac muscle tissue growth GO:0055021 26 0.724
spermatid differentiation GO:0048515 115 0.721
regulation of cell activation GO:0050865 289 0.721
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.720
positive regulation of cardiac muscle tissue growth GO:0055023 15 0.720
nephron tubule morphogenesis GO:0072078 68 0.719
ventricular septum morphogenesis GO:0060412 27 0.718
regulation of osteoblast proliferation GO:0033688 15 0.716
Mouse
regulation of purine nucleotide metabolic process GO:1900542 169 0.714
negative regulation of protein depolymerization GO:1901880 21 0.714
regulation of vesicle mediated transport GO:0060627 139 0.712
Rat
formation of radial glial scaffolds GO:0021943 4 0.712
positive regulation of heart growth GO:0060421 18 0.712
regulation of vasculogenesis GO:2001212 9 0.712
digestive tract morphogenesis GO:0048546 147 0.705
Human Zebrafish Fly
carbohydrate homeostasis GO:0033500 128 0.704
positive regulation of cellular amine metabolic process GO:0033240 5 0.703
regulation of mitotic cell cycle GO:0007346 126 0.698
nephron development GO:0072006 109 0.697
regulation of secretion GO:0051046 274 0.694
positive regulation of peptide secretion GO:0002793 33 0.689
establishment of organelle localization GO:0051656 122 0.688
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.688
negative regulation of cell activation GO:0050866 111 0.687
receptor mediated endocytosis GO:0006898 51 0.687
regulation of ion transport GO:0043269 215 0.685
odontogenesis GO:0042476 78 0.685
stem cell development GO:0048864 219 0.684
Fly
ureteric bud development GO:0001657 94 0.681
smooth muscle tissue development GO:0048745 22 0.680
regulation of neuron differentiation GO:0045664 281 0.680
Rat
mesenchymal cell differentiation GO:0048762 107 0.680
divalent inorganic cation homeostasis GO:0072507 138 0.678
Rat
hemostasis GO:0007599 78 0.677
response to corticosterone GO:0051412 1 0.677
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.677
Mouse
protein localization to membrane GO:0072657 108 0.677
Human
eye photoreceptor cell differentiation GO:0001754 41 0.675
neural fold elevation formation GO:0021502 1 0.673
regulation of metal ion transport GO:0010959 106 0.672
regulation of establishment of protein localization GO:0070201 181 0.672
Human
regulation of protein stability GO:0031647 52 0.670
nephron epithelium development GO:0072009 92 0.670
neuroblast fate commitment GO:0014017 1 0.670
retina vasculature development in camera type eye GO:0061298 17 0.669
ephrin receptor signaling pathway GO:0048013 20 0.669
cardiac muscle cell proliferation GO:0060038 31 0.666
negative regulation of lymphocyte proliferation GO:0050672 45 0.666
purine nucleoside metabolic process GO:0042278 241 0.666
amine metabolic process GO:0009308 45 0.662
pigment metabolic process GO:0042440 32 0.658
placenta development GO:0001890 140 0.658
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.654
regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902041 22 0.654
cellular amino acid metabolic process GO:0006520 103 0.652
positive regulation of nitric oxide synthase activity GO:0051000 2 0.650
ion transmembrane transport GO:0034220 361 0.649
peptidyl tyrosine phosphorylation GO:0018108 143 0.649
Rat
positive regulation of protein phosphorylation GO:0001934 242 0.647
Rat
gastrulation GO:0007369 116 0.647
Human Zebrafish Fly
positive regulation of cellular component biogenesis GO:0044089 94 0.647
cerebral cortex development GO:0021987 86 0.644
mitral valve morphogenesis GO:0003183 4 0.644
positive regulation of smooth muscle cell migration GO:0014911 4 0.644
mitotic cell cycle GO:0000278 195 0.643
regulation of nucleotide catabolic process GO:0030811 122 0.643
endocardial cell differentiation GO:0060956 4 0.638
genitalia development GO:0048806 37 0.638
Fly
ensheathment of neurons GO:0007272 76 0.635
regulation of lymphocyte activation GO:0051249 240 0.633
organonitrogen compound catabolic process GO:1901565 264 0.633
cognition GO:0050890 149 0.633
cellular response to insulin stimulus GO:0032869 78 0.632
negative regulation of synapse assembly GO:0051964 3 0.632
dna metabolic process GO:0006259 303 0.632
cellular response to amino acid stimulus GO:0071230 29 0.630
cellular amine metabolic process GO:0044106 44 0.629
peptidyl amino acid modification GO:0018193 336 0.629
Rat
hypoxia inducible factor 1alpha signaling pathway GO:0097411 2 0.628
positive regulation of monooxygenase activity GO:0032770 2 0.627
negative regulation of mitotic cell cycle GO:0045930 58 0.626
carbon catabolite regulation of transcription GO:0045990 4 0.625
cellular response to dna damage stimulus GO:0006974 207 0.625
embryonic heart tube morphogenesis GO:0003143 51 0.625
renal system development GO:0072001 225 0.625
neuronal action potential GO:0019228 54 0.624
regulation of erk1 and erk2 cascade GO:0070372 71 0.623
positive regulation of cardiac muscle cell differentiation GO:2000727 6 0.622
regulation of binding GO:0051098 111 0.621
cell substrate junction assembly GO:0007044 24 0.620
Mouse
positive regulation of wnt signaling pathway GO:0030177 45 0.615
negative regulation of molecular function GO:0044092 258 0.615
sensory perception GO:0007600 245 0.613
Fly
camera type eye development GO:0043010 266 0.612
cellular component assembly involved in morphogenesis GO:0010927 139 0.611
telencephalon cell migration GO:0022029 55 0.611
cardiogenic plate morphogenesis GO:0003142 1 0.610
regulation of cell migration GO:0030334 219 0.610
Mouse Rat Fly
regulation of glial cell differentiation GO:0045685 41 0.606
regulation of response to wounding GO:1903034 189 0.605
cell migration involved in endocardial cushion formation GO:0003273 3 0.602
vesicle localization GO:0051648 86 0.602
cell growth GO:0016049 130 0.598
positive regulation of transferase activity GO:0051347 167 0.597
positive regulation of proteolysis GO:0045862 85 0.596
glycosyl compound metabolic process GO:1901657 246 0.594
positive regulation of neuron death GO:1901216 28 0.592
renal tubule development GO:0061326 87 0.590
activation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:0097296 2 0.587
ribonucleotide catabolic process GO:0009261 208 0.584
defense response to bacterium GO:0042742 119 0.583
negative regulation of kinase activity GO:0033673 81 0.583
pyramidal neuron migration GO:0021852 1 0.582
regulation of ion homeostasis GO:2000021 64 0.581
regulation of axon extension GO:0030516 43 0.581
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.579
negative regulation of wnt signaling pathway involved in heart development GO:0003308 4 0.578
neuron projection extension GO:1990138 64 0.578
digestive tract development GO:0048565 190 0.578
Human Zebrafish Fly
leukocyte chemotaxis GO:0030595 69 0.577
Mouse
phospholipid metabolic process GO:0006644 87 0.577
positive regulation of leukocyte proliferation GO:0070665 73 0.574
positive regulation of protein modification process GO:0031401 299 0.573
Rat
regulation of glial cell proliferation GO:0060251 8 0.573
regulation of cell shape GO:0008360 39 0.572
Fly
negative regulation of glial cell differentiation GO:0045686 21 0.571
regulation of mitotic cell cycle phase transition GO:1901990 73 0.570
renal filtration cell differentiation GO:0061318 10 0.569
negative regulation of cell adhesion GO:0007162 45 0.568
positive regulation of mitotic cell cycle GO:0045931 41 0.565
response to peptide GO:1901652 136 0.565
endothelial cell migration GO:0043542 44 0.564
positive regulation of cell migration GO:0030335 109 0.564
Mouse Rat
cellular component maintenance GO:0043954 11 0.561
regulation of endocytosis GO:0030100 69 0.561
Rat
cell migration involved in sprouting angiogenesis GO:0002042 9 0.560
regulation of cell proliferation involved in outflow tract morphogenesis GO:1901963 2 0.559
mesangial cell differentiation GO:0072007 4 0.558
central nervous system morphogenesis GO:0021551 2 0.557
mapk cascade GO:0000165 281 0.556
Rat
pole plasm assembly GO:0007315 2 0.555
stem cell proliferation GO:0072089 117 0.555
leukocyte migration GO:0050900 124 0.555
Human Mouse
developmental growth involved in morphogenesis GO:0060560 138 0.554
negative regulation of thymocyte apoptotic process GO:0070244 8 0.554
regulation of phagocytosis GO:0050764 33 0.551
metal ion homeostasis GO:0055065 189 0.548
Rat
liver development GO:0001889 66 0.547
negative regulation of blood vessel endothelial cell migration GO:0043537 3 0.545
retina morphogenesis in camera type eye GO:0060042 45 0.541
positive regulation of keratinocyte differentiation GO:0045618 3 0.540
regulation of nucleotide metabolic process GO:0006140 169 0.537
molting cycle GO:0042303 90 0.536
regulation of cellular amino acid metabolic process GO:0006521 5 0.536
focal adhesion assembly GO:0048041 19 0.536
cell junction assembly GO:0034329 52 0.535
Mouse Rat
regulation of g1 s transition of mitotic cell cycle GO:2000045 35 0.534
calcium ion transport GO:0006816 159 0.534
arterial endothelial cell differentiation GO:0060842 5 0.531
muscle tissue morphogenesis GO:0060415 53 0.531
positive regulation of leukocyte differentiation GO:1902107 86 0.529
positive regulation of myeloid leukocyte differentiation GO:0002763 26 0.528
regulation of cgmp metabolic process GO:0030823 12 0.527
positive regulation of neuron apoptotic process GO:0043525 25 0.522
actin polymerization or depolymerization GO:0008154 54 0.521
regulation of osteoblast differentiation GO:0045667 67 0.519
respiratory system development GO:0060541 190 0.519
Fly
tissue remodeling GO:0048771 102 0.519
apoptotic process involved in embryonic digit morphogenesis GO:1902263 3 0.517
negative regulation of cellular component organization GO:0051129 194 0.517
Rat
cellular response to extracellular stimulus GO:0031668 81 0.516
Rat
nucleoside monophosphate metabolic process GO:0009123 85 0.513
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.512
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 35 0.512
kidney morphogenesis GO:0060993 83 0.509
regulation of cellular component biogenesis GO:0044087 181 0.507
Fly
cell recognition GO:0008037 83 0.506
mesonephric tubule morphogenesis GO:0072171 63 0.505
positive regulation of cell projection organization GO:0031346 95 0.505
Rat
leukocyte differentiation GO:0002521 342 0.505
carbohydrate metabolic process GO:0005975 230 0.504
negative regulation of transcription from rna polymerase ii promoter in response to stress GO:0097201 1 0.504
epithelial to mesenchymal transition involved in endocardial cushion formation GO:0003198 10 0.503
regulation of actin cytoskeleton organization GO:0032956 84 0.503
Fly
regulation of cell cycle process GO:0010564 160 0.502
regulation of mapk cascade GO:0043408 248 0.499
Rat
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.498
negative regulation of cardiac muscle tissue development GO:0055026 8 0.497
response to oxygen levels GO:0070482 62 0.494
cardiac muscle tissue development GO:0048738 130 0.493
regulation of phospholipase c activity GO:1900274 3 0.493
regulation of smooth muscle cell migration GO:0014910 6 0.491
metanephros development GO:0001656 79 0.490
determination of heart left right asymmetry GO:0061371 48 0.490
glomerular capillary formation GO:0072104 6 0.489
calcium mediated signaling GO:0019722 46 0.488
mechanoreceptor differentiation GO:0042490 67 0.487
meiotic cell cycle GO:0051321 122 0.487
metanephric glomerulus vasculature morphogenesis GO:0072276 3 0.482
metanephric glomerular epithelium development GO:0072244 3 0.482
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.481
Mouse
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.480
epithelial cell differentiation involved in prostate gland development GO:0060742 13 0.479
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.478
regulation of cardioblast differentiation GO:0051890 3 0.477
negative regulation of phosphorylation GO:0042326 166 0.476
salivary gland morphogenesis GO:0007435 33 0.476
purine ribonucleotide metabolic process GO:0009150 290 0.474
developmental maturation GO:0021700 193 0.473
ribonucleoside metabolic process GO:0009119 245 0.471
lung vasculature development GO:0060426 7 0.471
endomembrane system organization GO:0010256 147 0.468
Human
cardiac muscle cell development GO:0055013 39 0.468
cardiac right atrium morphogenesis GO:0003213 3 0.467
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.466
protein o linked glycosylation GO:0006493 16 0.463
inflammatory response GO:0006954 244 0.463
Mouse
response to alcohol GO:0097305 48 0.462
Rat
g1 s transition of mitotic cell cycle GO:0000082 57 0.461
tyrosine phosphorylation of stat3 protein GO:0042503 12 0.458
labyrinthine layer development GO:0060711 49 0.457
organelle fission GO:0048285 170 0.457
axon regeneration GO:0031103 12 0.457
purine nucleoside triphosphate metabolic process GO:0009144 226 0.456

Itgb1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 1.000
cancer DOID:162 0 0.994
organ system cancer DOID:0050686 0 0.990
disease of anatomical entity DOID:7 0 0.766
gastrointestinal system disease DOID:77 0 0.766
musculoskeletal system disease DOID:17 0 0.660
myopathy DOID:423 0 0.624
muscular disease DOID:0080000 0 0.624
heart disease DOID:114 0 0.624
cardiomyopathy DOID:0050700 0 0.624
intrinsic cardiomyopathy DOID:0060036 0 0.624
cardiovascular system disease DOID:1287 0 0.624
muscle tissue disease DOID:66 0 0.624
immune system cancer DOID:0060083 0 0.564
benign neoplasm DOID:0060072 0 0.519
dilated cardiomyopathy DOID:12930 0 0.460