|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.780
|
Mouse |
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.592
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.488
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.479
|
|
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.477
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.438
|
|
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.385
|
Mouse |
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.365
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.356
|
Mouse |
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.333
|
|
|
|
regulation of insulin receptor signaling pathway
|
GO:0046626 |
21 |
0.328
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.318
|
Mouse |
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.308
|
Mouse |
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.306
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.299
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.298
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.286
|
Mouse |
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.283
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.281
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.269
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.265
|
Mouse |
|
|
negative regulation of cellular response to insulin stimulus
|
GO:1900077 |
16 |
0.265
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.258
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.250
|
|
|
|
dephosphorylation
|
GO:0016311 |
129 |
0.247
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.245
|
Mouse |
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.241
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.240
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.238
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.235
|
Mouse |
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.233
|
|
|
|
negative regulation of insulin receptor signaling pathway
|
GO:0046627 |
14 |
0.228
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.225
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.201
|
Mouse |
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
92 |
0.201
|
Mouse |
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.198
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.193
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.192
|
Mouse |
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.191
|
Mouse |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.190
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
81 |
0.190
|
|
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.179
|
Mouse |
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.174
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
147 |
0.173
|
|
|
|
apical constriction
|
GO:0003383 |
4 |
0.170
|
Fly |
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.162
|
Mouse |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.161
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.161
|
Mouse |
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.160
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.158
|
|
|
|
cell adhesion
|
GO:0007155 |
329 |
0.158
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.154
|
Mouse |
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.151
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.150
|
Mouse |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.144
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.141
|
Mouse |
|
|
inflammatory response
|
GO:0006954 |
244 |
0.141
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.140
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.139
|
Fly |
|
|
ribonucleoside metabolic process
|
GO:0009119 |
245 |
0.138
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.136
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.136
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.130
|
|
|
|
t cell activation
|
GO:0042110 |
289 |
0.129
|
Zebrafish Mouse |
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.128
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.125
|
Mouse |
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.124
|
|
|
|
tyrosine phosphorylation of stat1 protein
|
GO:0042508 |
3 |
0.123
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.122
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.121
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.120
|
Mouse |
|
|
positive regulation of response to wounding
|
GO:1903036 |
66 |
0.119
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.118
|
|
|
|
spermatogenesis
|
GO:0007283 |
284 |
0.116
|
|
|
|
response to interleukin 15
|
GO:0070672 |
3 |
0.114
|
Human |
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.114
|
Mouse |
|
|
negative regulation of transferase activity
|
GO:0051348 |
85 |
0.114
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.113
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
29 |
0.111
|
|
|
|
regulation of actin filament polymerization
|
GO:0030833 |
38 |
0.110
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.110
|
Mouse |
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.110
|
|
|
|
digestive system development
|
GO:0055123 |
200 |
0.109
|
Fly |
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.107
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.107
|
Mouse |
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.104
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.104
|
Mouse |
|
|
actin filament organization
|
GO:0007015 |
113 |
0.102
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.102
|
Mouse |
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.101
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
222 |
0.101
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.099
|
|
|
|
insulin receptor signaling pathway
|
GO:0008286 |
49 |
0.098
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
199 |
0.097
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.097
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.096
|
Mouse Fly |
|
|
organelle fission
|
GO:0048285 |
170 |
0.096
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
84 |
0.096
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.095
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
55 |
0.095
|
Mouse |
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.095
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.095
|
|
|
|
activation of janus kinase activity
|
GO:0042976 |
2 |
0.095
|
Mouse |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.093
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
129 |
0.093
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.093
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.092
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.092
|
|
|
|
regulation of lymphocyte proliferation
|
GO:0050670 |
117 |
0.092
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.091
|
|
|
|
positive regulation of gamma delta t cell differentiation
|
GO:0045588 |
6 |
0.091
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.090
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.089
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.088
|
Mouse |
|
|
somatic diversification of immune receptors via germline recombination within a single locus
|
GO:0002562 |
51 |
0.088
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.087
|
Mouse |
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.086
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.086
|
Mouse |
|
|
long term memory
|
GO:0007616 |
15 |
0.086
|
Fly |
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
65 |
0.085
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.085
|
Mouse |
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.083
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.083
|
|
|
|
cognition
|
GO:0050890 |
149 |
0.083
|
Fly |
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
56 |
0.081
|
Mouse |
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
122 |
0.081
|
|
|
|
activation of immune response
|
GO:0002253 |
138 |
0.081
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.080
|
Mouse |
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.080
|
Mouse |
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.080
|
|
|
|
stem cell development
|
GO:0048864 |
219 |
0.080
|
Fly |
|
|
germ cell development
|
GO:0007281 |
185 |
0.079
|
Fly |
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.078
|
Mouse |
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.078
|
|
|
|
response to growth factor
|
GO:0070848 |
198 |
0.077
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.077
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.077
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
88 |
0.077
|
|
|
|
negative regulation of t cell differentiation
|
GO:0045581 |
23 |
0.076
|
Mouse |
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.076
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.076
|
Mouse |
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.075
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.075
|
Mouse |
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.075
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
45 |
0.074
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.073
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.072
|
|
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.072
|
Mouse |
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.072
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.072
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.071
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
54 |
0.071
|
|
|
|
immunoglobulin production
|
GO:0002377 |
73 |
0.070
|
|
|
|
membrane organization
|
GO:0061024 |
245 |
0.070
|
|
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.070
|
Mouse |
|
|
regulation of t cell proliferation
|
GO:0042129 |
92 |
0.070
|
|
|
|
negative regulation of peptidyl tyrosine phosphorylation
|
GO:0050732 |
17 |
0.069
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.069
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.068
|
Zebrafish Mouse |
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.068
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.068
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
154 |
0.068
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.067
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.067
|
Mouse |
|
|
maintenance of location
|
GO:0051235 |
89 |
0.067
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
65 |
0.067
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
88 |
0.066
|
|
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.066
|
Mouse |
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.066
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
45 |
0.066
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
87 |
0.065
|
Mouse |
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.063
|
|
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.063
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.063
|
Mouse |
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.062
|
Mouse |
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.062
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
116 |
0.062
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
133 |
0.061
|
|
|
|
positive regulation of alpha beta t cell activation
|
GO:0046635 |
39 |
0.061
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.061
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.061
|
Mouse |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.060
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.060
|
Zebrafish Mouse |
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.059
|
Mouse |
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.059
|
|
|
|
regulation of cd4 positive alpha beta t cell activation
|
GO:2000514 |
24 |
0.059
|
Mouse |
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.059
|
Mouse |
|
|
regulation of response to cytokine stimulus
|
GO:0060759 |
23 |
0.058
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.057
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.057
|
Mouse |
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.057
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.057
|
|
|
|
skeletal system development
|
GO:0001501 |
356 |
0.057
|
|
|
|
neuron projection guidance
|
GO:0097485 |
141 |
0.057
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.056
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.056
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
148 |
0.056
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.056
|
Mouse |
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
52 |
0.056
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.055
|
|
|
|
positive t cell selection
|
GO:0043368 |
23 |
0.055
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.055
|
Mouse |
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.055
|
|
|
|
muscle system process
|
GO:0003012 |
141 |
0.055
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
99 |
0.054
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.053
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
113 |
0.053
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.053
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
115 |
0.052
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.052
|
|
|
|
locomotory behavior
|
GO:0007626 |
195 |
0.052
|
Fly |
|
|
regulation of leukocyte mediated cytotoxicity
|
GO:0001910 |
38 |
0.051
|
|
|
|
lateral inhibition
|
GO:0046331 |
1 |
0.051
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.051
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.051
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.051
|
|
|
|
regulation of dendritic cell apoptotic process
|
GO:2000668 |
3 |
0.051
|
Mouse |
|
|
response to interleukin 4
|
GO:0070670 |
23 |
0.051
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.050
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.050
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.050
|
Mouse |
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.050
|
|
|
|
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002823 |
23 |
0.050
|
Mouse |
|
|
chromatin organization
|
GO:0006325 |
206 |
0.050
|
|
|
|
negative regulation of leukocyte mediated immunity
|
GO:0002704 |
29 |
0.049
|
Mouse |
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.049
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.048
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.048
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.048
|
|
|
|
heart process
|
GO:0003015 |
94 |
0.047
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.047
|
|
|
|
dna recombination
|
GO:0006310 |
92 |
0.047
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.047
|
|
|
|
regulation of immunoglobulin production
|
GO:0002637 |
42 |
0.047
|
|
|
|
mast cell proliferation
|
GO:0070662 |
4 |
0.046
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.046
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.046
|
Mouse |
|
|
glucose homeostasis
|
GO:0042593 |
128 |
0.046
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
88 |
0.046
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
241 |
0.045
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.045
|
Mouse |
|
|
cellular response to granulocyte macrophage colony stimulating factor stimulus
|
GO:0097011 |
3 |
0.045
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
206 |
0.044
|
|
|
|
negative regulation of inflammatory response
|
GO:0050728 |
61 |
0.044
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.044
|
Zebrafish Mouse |
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.044
|
|
|
|
neuron migration
|
GO:0001764 |
122 |
0.044
|
|
|
|
positive regulation of leukocyte mediated cytotoxicity
|
GO:0001912 |
31 |
0.043
|
|
|
|
oocyte anterior posterior axis specification
|
GO:0007314 |
2 |
0.043
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.043
|
|
|
|
memory
|
GO:0007613 |
58 |
0.043
|
Fly |
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.043
|
|
|
|
organ growth
|
GO:0035265 |
117 |
0.043
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.043
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
116 |
0.043
|
Mouse |
|
|
positive regulation of b cell activation
|
GO:0050871 |
49 |
0.043
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.042
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.042
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.042
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
40 |
0.042
|
|
|
|
regulation of tyrosine phosphorylation of stat1 protein
|
GO:0042510 |
2 |
0.042
|
|
|
|
mesodermal cell migration
|
GO:0008078 |
4 |
0.041
|
|
|
|
negative regulation of neuron apoptotic process
|
GO:0043524 |
92 |
0.041
|
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.041
|
|
|
|
histone modification
|
GO:0016570 |
159 |
0.041
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.041
|
|
|
|
midgut development
|
GO:0007494 |
4 |
0.041
|
|
|
|
tyrosine phosphorylation of stat3 protein
|
GO:0042503 |
12 |
0.041
|
Mouse |
|
|
positive regulation of alpha beta t cell differentiation
|
GO:0046638 |
28 |
0.041
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.041
|
|
|
|
t cell selection
|
GO:0045058 |
34 |
0.040
|
|
|
|
methylation
|
GO:0032259 |
134 |
0.040
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.040
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.040
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.040
|
|
|
|
neuron death
|
GO:0070997 |
154 |
0.040
|
|
|
|
regulation of cell division
|
GO:0051302 |
76 |
0.040
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.040
|
|
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.040
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.040
|
Mouse |
|
|
regulation of mast cell activation
|
GO:0033003 |
21 |
0.040
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.039
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
85 |
0.039
|
|
|
|
meiotic cell cycle
|
GO:0051321 |
122 |
0.039
|
|
|
|
interleukin 4 mediated signaling pathway
|
GO:0035771 |
2 |
0.039
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
56 |
0.039
|
|
|
|
response to granulocyte macrophage colony stimulating factor
|
GO:0097012 |
3 |
0.039
|
|
|
|
isotype switching
|
GO:0045190 |
36 |
0.039
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.039
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.039
|
Mouse |
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.038
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.038
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.038
|
Mouse |
|
|
nitrogen compound transport
|
GO:0071705 |
271 |
0.038
|
|
|
|
plasma membrane organization
|
GO:0007009 |
90 |
0.038
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
51 |
0.037
|
Mouse |
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.037
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.037
|
|
|
|
regulation of interleukin 2 production
|
GO:0032663 |
28 |
0.037
|
|
|
|
positive regulation of inflammatory response
|
GO:0050729 |
47 |
0.037
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.037
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.037
|
|
|
|
positive regulation of leukocyte mediated immunity
|
GO:0002705 |
70 |
0.037
|
|
|
|
peptidyl tyrosine dephosphorylation
|
GO:0035335 |
23 |
0.036
|
|
|
|
thymic t cell selection
|
GO:0045061 |
22 |
0.036
|
|
|
|
natural killer cell proliferation
|
GO:0001787 |
3 |
0.036
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.036
|
Mouse |
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.036
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.036
|
Mouse |
|
|
carbohydrate homeostasis
|
GO:0033500 |
128 |
0.036
|
|
|
|
interleukin 2 mediated signaling pathway
|
GO:0038110 |
2 |
0.036
|
Human |
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.036
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.036
|
|
|
|
gtp metabolic process
|
GO:0046039 |
144 |
0.036
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.035
|
Fly |
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.035
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
88 |
0.035
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.035
|
Mouse |
|
|
skin development
|
GO:0043588 |
220 |
0.035
|
|
|
|
heart contraction
|
GO:0060047 |
93 |
0.035
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.035
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.034
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.034
|
|
|
|
response to amino acid
|
GO:0043200 |
37 |
0.034
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
194 |
0.034
|
|
|
|
microtubule based process
|
GO:0007017 |
236 |
0.034
|
|
|
|
hormone mediated signaling pathway
|
GO:0009755 |
23 |
0.034
|
|
|
|
cellular response to interleukin 4
|
GO:0071353 |
21 |
0.034
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
133 |
0.034
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.034
|
|
|
|
interleukin 2 production
|
GO:0032623 |
33 |
0.034
|
|
|
|
platelet derived growth factor receptor signaling pathway
|
GO:0048008 |
32 |
0.034
|
|
|
|
gastrulation
|
GO:0007369 |
116 |
0.034
|
Fly |
|
|
actin filament polymerization
|
GO:0030041 |
44 |
0.033
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
78 |
0.033
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.033
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
163 |
0.033
|
|
|
|
somatic diversification of immunoglobulins
|
GO:0016445 |
43 |
0.033
|
|
|
|
positive thymic t cell selection
|
GO:0045059 |
13 |
0.033
|
|
|
|
learning or memory
|
GO:0007611 |
148 |
0.033
|
Fly |
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.033
|
Mouse |
|
|
mitochondrion distribution
|
GO:0048311 |
4 |
0.032
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.032
|
|
|
|
type i interferon signaling pathway
|
GO:0060337 |
10 |
0.032
|
|
|
|
cytokinesis
|
GO:0000910 |
17 |
0.032
|
|
|
|
t cell homeostasis
|
GO:0043029 |
35 |
0.032
|
Mouse |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.032
|
|
|
|
negative regulation of response to cytokine stimulus
|
GO:0060761 |
9 |
0.032
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.032
|
Mouse |
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.032
|
Mouse |
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
65 |
0.032
|
Mouse |
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
119 |
0.032
|
|
|
|
positive regulation of lymphocyte differentiation
|
GO:0045621 |
61 |
0.031
|
|
|
|
regulation of cellular response to insulin stimulus
|
GO:1900076 |
30 |
0.031
|
|
|
|
muscle tissue development
|
GO:0060537 |
308 |
0.031
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.031
|
Mouse |
|
|
positive regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903557 |
31 |
0.031
|
Mouse |
|
|
leukocyte mediated cytotoxicity
|
GO:0001909 |
62 |
0.031
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.031
|
|
|
|
lateral line system development
|
GO:0048925 |
1 |
0.031
|
|
|
|
regulation of dna recombination
|
GO:0000018 |
34 |
0.031
|
|
|
|
interferon gamma mediated signaling pathway
|
GO:0060333 |
5 |
0.031
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.031
|
Mouse |
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.031
|
Zebrafish |
|
|
positive regulation of dna templated transcription elongation
|
GO:0032786 |
2 |
0.031
|
|
|
|
meiotic cell cycle process
|
GO:1903046 |
77 |
0.031
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
52 |
0.030
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.030
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
85 |
0.030
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
156 |
0.030
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.030
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.030
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
231 |
0.030
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.030
|
|
|
|
cellular response to type i interferon
|
GO:0071357 |
10 |
0.030
|
|
|
|
regulation of mast cell proliferation
|
GO:0070666 |
4 |
0.029
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
89 |
0.029
|
Mouse |
|
|
myeloid cell apoptotic process
|
GO:0033028 |
22 |
0.029
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.029
|
|
|
|
cellular response to interleukin 6
|
GO:0071354 |
9 |
0.029
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.029
|
|
|
|
regulation of cd4 positive alpha beta t cell differentiation
|
GO:0043370 |
21 |
0.029
|
Mouse |
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.029
|
|
|
|
jak stat cascade involved in growth hormone signaling pathway
|
GO:0060397 |
4 |
0.029
|
Mouse |
|
|
atp catabolic process
|
GO:0006200 |
55 |
0.029
|
|
|
|
positive regulation of phosphatase activity
|
GO:0010922 |
4 |
0.028
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
80 |
0.028
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.028
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
62 |
0.028
|
Mouse |
|
|
cellular response to interleukin 15
|
GO:0071350 |
2 |
0.028
|
Human |
|
|
regulation of alpha beta t cell differentiation
|
GO:0046637 |
35 |
0.028
|
Mouse |
|
|
regulation of cellular carbohydrate metabolic process
|
GO:0010675 |
75 |
0.028
|
|
|
|
somatic recombination of immunoglobulin gene segments
|
GO:0016447 |
42 |
0.028
|
|
|
|
neuron apoptotic process
|
GO:0051402 |
142 |
0.027
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.027
|
|
|
|
blood circulation
|
GO:0008015 |
195 |
0.027
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.027
|
|
|
|
tyrosine phosphorylation of stat5 protein
|
GO:0042506 |
9 |
0.027
|
Mouse |
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.027
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
61 |
0.027
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.026
|
Fly |
|
|
formation of primary germ layer
|
GO:0001704 |
77 |
0.026
|
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.026
|
|
|
|
bone development
|
GO:0060348 |
120 |
0.026
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
83 |
0.026
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
59 |
0.026
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.026
|
Mouse |
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
205 |
0.026
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.026
|
|
|
|
somatic diversification of immunoglobulins involved in immune response
|
GO:0002208 |
36 |
0.026
|
|
|
|
interleukin 6 mediated signaling pathway
|
GO:0070102 |
6 |
0.026
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
33 |
0.026
|
|
|
|
circulatory system process
|
GO:0003013 |
197 |
0.026
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.026
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.026
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.026
|
Mouse |
|
|
spermatid differentiation
|
GO:0048515 |
115 |
0.026
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.025
|
Mouse |
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
169 |
0.025
|
|
|
|
hepatocyte growth factor receptor signaling pathway
|
GO:0048012 |
3 |
0.025
|
|
|
|
negative regulation of tyrosine phosphorylation of stat protein
|
GO:0042532 |
3 |
0.025
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.025
|
|
|
|
positive regulation of insulin secretion
|
GO:0032024 |
26 |
0.025
|
|
|
|
camera type eye development
|
GO:0043010 |
266 |
0.025
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.025
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
122 |
0.025
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.025
|
|
|
|
oocyte construction
|
GO:0007308 |
2 |
0.025
|
|
|
|
regulation of lamellipodium assembly
|
GO:0010591 |
3 |
0.025
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.025
|
|
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
57 |
0.025
|
|
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
61 |
0.025
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.025
|
|
|
|
atp metabolic process
|
GO:0046034 |
75 |
0.024
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.024
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.024
|
|
|
|
dendrite development
|
GO:0016358 |
115 |
0.024
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.024
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.024
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.024
|
|
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
41 |
0.024
|
Mouse |
|
|
positive regulation of hematopoietic stem cell migration
|
GO:2000473 |
1 |
0.024
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
98 |
0.024
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.024
|
|
|
|
cellular response to interferon gamma
|
GO:0071346 |
25 |
0.024
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.023
|
Fly |
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.023
|
|
|
|
negative regulation of neuron death
|
GO:1901215 |
98 |
0.023
|
|
|
|
tolerance induction to self antigen
|
GO:0002513 |
4 |
0.023
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.023
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.023
|
|
|
|
leukocyte homeostasis
|
GO:0001776 |
79 |
0.023
|
Mouse |
|
|
progesterone metabolic process
|
GO:0042448 |
4 |
0.023
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
56 |
0.023
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
73 |
0.023
|
|
|
|
chromatin modification
|
GO:0016568 |
187 |
0.023
|
|
|
|
gland development
|
GO:0048732 |
330 |
0.023
|
Mouse Fly |
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.023
|
|
|
|
macromolecule methylation
|
GO:0043414 |
120 |
0.023
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
71 |
0.022
|
|
|
|
regulation of protein binding
|
GO:0043393 |
60 |
0.022
|
|
|
|
valine metabolic process
|
GO:0006573 |
4 |
0.022
|
|
|
|
central nervous system neuron differentiation
|
GO:0021953 |
162 |
0.022
|
|
|
|
jnk cascade
|
GO:0007254 |
72 |
0.022
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.022
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.022
|
|
|
|
positive regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032436 |
23 |
0.022
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
56 |
0.022
|
|
|
|
connective tissue development
|
GO:0061448 |
179 |
0.022
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.022
|
Fly |
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.022
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.022
|
Mouse |
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
155 |
0.022
|
|
|
|
opsonization
|
GO:0008228 |
3 |
0.022
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
83 |
0.022
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
90 |
0.022
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
67 |
0.022
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.022
|
|
|
|
adherens junction organization
|
GO:0034332 |
28 |
0.022
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
85 |
0.022
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.022
|
|
|
|
gamma delta t cell differentiation
|
GO:0042492 |
11 |
0.021
|
|
|
|
negative regulation of platelet derived growth factor receptor beta signaling pathway
|
GO:2000587 |
2 |
0.021
|
|
|
|
negative regulation of glycoprotein metabolic process
|
GO:1903019 |
3 |
0.021
|
Mouse |
|
|
endocytosis
|
GO:0006897 |
168 |
0.021
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
151 |
0.021
|
|
|
|
negative regulation of t cell proliferation
|
GO:0042130 |
38 |
0.021
|
|
|
|
ventricular cardiac myofibril assembly
|
GO:0055005 |
3 |
0.021
|
|
|
|
mammary gland epithelium development
|
GO:0061180 |
65 |
0.021
|
Mouse |
|
|
peptide secretion
|
GO:0002790 |
114 |
0.021
|
|
