|
|
regulation of insulin receptor signaling pathway
|
GO:0046626 |
21 |
0.999
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.998
|
|
|
|
regulation of t cell differentiation
|
GO:0045580 |
83 |
0.997
|
Mouse |
|
|
t cell activation
|
GO:0042110 |
289 |
0.997
|
Mouse |
|
|
activation of janus kinase activity
|
GO:0042976 |
2 |
0.995
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.994
|
|
|
|
negative regulation of insulin receptor signaling pathway
|
GO:0046627 |
14 |
0.991
|
|
|
|
regulation of t helper 1 cell differentiation
|
GO:0045625 |
7 |
0.991
|
Mouse |
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.989
|
Mouse |
|
|
regulation of cd4 positive alpha beta t cell activation
|
GO:2000514 |
24 |
0.978
|
Mouse |
|
|
regulation of activation of jak2 kinase activity
|
GO:0010534 |
1 |
0.977
|
|
|
|
response to peptide hormone
|
GO:0043434 |
127 |
0.971
|
|
|
|
cd4 positive alpha beta t cell differentiation involved in immune response
|
GO:0002294 |
28 |
0.970
|
Mouse |
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.967
|
Mouse |
|
|
t helper cell differentiation
|
GO:0042093 |
28 |
0.964
|
Mouse |
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
41 |
0.963
|
Mouse |
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.959
|
Mouse |
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.959
|
Mouse |
|
|
gland development
|
GO:0048732 |
330 |
0.957
|
|
|
|
alpha beta t cell differentiation involved in immune response
|
GO:0002293 |
30 |
0.957
|
Mouse |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
5 |
0.955
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
88 |
0.954
|
|
|
|
negative regulation of peptidyl tyrosine phosphorylation
|
GO:0050732 |
17 |
0.953
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.951
|
Mouse |
|
|
cd4 positive alpha beta t cell activation
|
GO:0035710 |
45 |
0.949
|
Mouse |
|
|
cellular response to peptide
|
GO:1901653 |
92 |
0.947
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.945
|
|
|
|
regulation of cd4 positive alpha beta t cell differentiation
|
GO:0043370 |
21 |
0.940
|
Mouse |
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.940
|
Rat |
|
|
insulin receptor signaling pathway
|
GO:0008286 |
49 |
0.939
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.937
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.934
|
Mouse |
|
|
peptidyl amino acid modification
|
GO:0018193 |
336 |
0.934
|
|
|
|
negative regulation of t helper 2 cell differentiation
|
GO:0045629 |
4 |
0.932
|
|
|
|
t cell activation involved in immune response
|
GO:0002286 |
43 |
0.924
|
Mouse |
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.913
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
103 |
0.912
|
|
|
|
positive regulation of t cell differentiation
|
GO:0045582 |
52 |
0.901
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.901
|
Mouse |
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.892
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.884
|
Mouse |
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.867
|
Mouse |
|
|
negative regulation of cell activation
|
GO:0050866 |
111 |
0.864
|
Mouse |
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
92 |
0.861
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.860
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
86 |
0.856
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.855
|
|
|
|
response to peptide
|
GO:1901652 |
136 |
0.854
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.852
|
|
|
|
immune effector process
|
GO:0002252 |
321 |
0.850
|
Mouse Fly |
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.843
|
Mouse Rat |
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.835
|
Mouse |
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
51 |
0.829
|
Mouse |
|
|
negative regulation of cellular response to insulin stimulus
|
GO:1900077 |
16 |
0.828
|
|
|
|
tyrosine phosphorylation of stat1 protein
|
GO:0042508 |
3 |
0.826
|
Rat |
|
|
lactation
|
GO:0007595 |
25 |
0.818
|
|
|
|
regulation of t helper cell differentiation
|
GO:0045622 |
14 |
0.815
|
Mouse |
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.814
|
|
|
|
t helper 1 cell differentiation
|
GO:0045063 |
13 |
0.814
|
Mouse |
|
|
alpha beta t cell activation involved in immune response
|
GO:0002287 |
31 |
0.811
|
Mouse |
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
247 |
0.806
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.805
|
Rat |
|
|
activation of immune response
|
GO:0002253 |
138 |
0.803
|
|
|
|
t cell differentiation involved in immune response
|
GO:0002292 |
30 |
0.801
|
Mouse |
|
|
jak stat cascade
|
GO:0007259 |
42 |
0.800
|
|
|
|
protein kinase c activating g protein coupled receptor signaling pathway
|
GO:0007205 |
4 |
0.793
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.793
|
|
|
|
radial glia guided migration of purkinje cell
|
GO:0021942 |
6 |
0.786
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
1 |
0.760
|
|
|
|
negative regulation of tyrosine phosphorylation of stat protein
|
GO:0042532 |
3 |
0.757
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.753
|
Mouse |
|
|
lymphocyte homeostasis
|
GO:0002260 |
64 |
0.753
|
Mouse |
|
|
regulation of activation of janus kinase activity
|
GO:0010533 |
1 |
0.748
|
|
|
|
positive regulation of lymphocyte differentiation
|
GO:0045621 |
61 |
0.746
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
0 |
0.734
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
78 |
0.732
|
|
|
|
positive regulation of alpha beta t cell differentiation
|
GO:0046638 |
28 |
0.731
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.729
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.727
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.726
|
Human Rat |
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.719
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
65 |
0.718
|
Mouse |
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.714
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.706
|
|
|
|
regulation of alpha beta t cell activation
|
GO:0046634 |
53 |
0.697
|
Mouse |
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.697
|
Mouse |
|
|
negative regulation of lymphocyte differentiation
|
GO:0045620 |
32 |
0.696
|
Mouse |
|
|
lymphocyte mediated immunity
|
GO:0002449 |
139 |
0.694
|
|
|
|
regulation of tyrosine phosphorylation of stat1 protein
|
GO:0042510 |
2 |
0.693
|
|
|
|
stem cell differentiation
|
GO:0048863 |
268 |
0.685
|
Fly |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.678
|
|
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.661
|
Mouse |
|
|
response to interferon gamma
|
GO:0034341 |
34 |
0.654
|
Rat |
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.646
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
195 |
0.643
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
210 |
0.642
|
|
|
|
regulation of tyrosine phosphorylation of stat protein
|
GO:0042509 |
20 |
0.639
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.634
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.627
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
29 |
0.626
|
|
|
|
positive regulation of cd4 positive alpha beta t cell differentiation
|
GO:0043372 |
14 |
0.614
|
|
|
|
tyrosine phosphorylation of stat5 protein
|
GO:0042506 |
9 |
0.614
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.614
|
|
|
|
regulation of alpha beta t cell differentiation
|
GO:0046637 |
35 |
0.609
|
Mouse |
|
|
layer formation in cerebral cortex
|
GO:0021819 |
13 |
0.606
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
46 |
0.605
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.604
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
150 |
0.602
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.602
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
247 |
0.596
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.595
|
|
|
|
regulation of type 2 immune response
|
GO:0002828 |
18 |
0.590
|
|
|
|
negative regulation of tyrosine phosphorylation of stat3 protein
|
GO:0042518 |
1 |
0.589
|
|
|
|
response to insulin
|
GO:0032868 |
100 |
0.571
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.570
|
Mouse |
|
|
mammary gland epithelium development
|
GO:0061180 |
65 |
0.561
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.561
|
|
|
|
nuclear division
|
GO:0000280 |
158 |
0.553
|
|
|
|
regulation of lymphocyte differentiation
|
GO:0045619 |
107 |
0.551
|
Mouse |
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.548
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.546
|
|
|
|
response to amino acid
|
GO:0043200 |
37 |
0.544
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.543
|
|
|
|
regulation of tyrosine phosphorylation of stat3 protein
|
GO:0042516 |
10 |
0.536
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
160 |
0.527
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.524
|
Mouse |
|
|
cellular response to amino acid stimulus
|
GO:0071230 |
29 |
0.523
|
|
|
|
response to interleukin 6
|
GO:0070741 |
10 |
0.521
|
|
|
|
b cell activation
|
GO:0042113 |
161 |
0.514
|
Mouse |
|
|
regulation of cell cycle
|
GO:0051726 |
281 |
0.507
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
55 |
0.505
|
Mouse |
|
|
positive regulation of cd4 positive alpha beta t cell activation
|
GO:2000516 |
16 |
0.502
|
|
|
|
exocytosis
|
GO:0006887 |
121 |
0.499
|
|
|
|
negative regulation of t helper cell differentiation
|
GO:0045623 |
9 |
0.490
|
Mouse |
|
|
fat cell differentiation
|
GO:0045444 |
160 |
0.479
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.477
|
Rat |
|
|
protein secretion
|
GO:0009306 |
111 |
0.477
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.472
|
|
|
|
cytokine production
|
GO:0001816 |
319 |
0.467
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.451
|
|
|
|
regulation of t helper 1 type immune response
|
GO:0002825 |
17 |
0.451
|
Mouse |
|
|
negative regulation of cd4 positive alpha beta t cell activation
|
GO:2000515 |
10 |
0.448
|
Mouse |
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.447
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.447
|
Human Rat |
|
|
tyrosine phosphorylation of stat3 protein
|
GO:0042503 |
12 |
0.444
|
|
|
|
response to interleukin 15
|
GO:0070672 |
3 |
0.439
|
|
|
|
regulation of cellular response to insulin stimulus
|
GO:1900076 |
30 |
0.438
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.437
|
Mouse |
|
|
regulation of jak stat cascade
|
GO:0046425 |
34 |
0.436
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.418
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
166 |
0.416
|
|
|
|
positive regulation of t helper 1 cell differentiation
|
GO:0045627 |
4 |
0.413
|
|
|
|
regulation of leukocyte apoptotic process
|
GO:2000106 |
56 |
0.411
|
Mouse |
|
|
stem cell development
|
GO:0048864 |
219 |
0.409
|
Fly |
|
|
natural killer cell proliferation
|
GO:0001787 |
3 |
0.408
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.408
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.403
|
|
|
|
response to ketone
|
GO:1901654 |
15 |
0.395
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.391
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.389
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.389
|
|
|
|
organ regeneration
|
GO:0031100 |
2 |
0.385
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
282 |
0.383
|
Mouse |
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.380
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
242 |
0.379
|
Fly |
|
|
neuron death
|
GO:0070997 |
154 |
0.378
|
Rat |
|
|
cellular response to interferon gamma
|
GO:0071346 |
25 |
0.375
|
Rat |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.366
|
|
|
|
regulation of exocytosis
|
GO:0017157 |
61 |
0.363
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.361
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.361
|
Rat |
|
|
negative regulation of alpha beta t cell activation
|
GO:0046636 |
18 |
0.355
|
Mouse |
|
|
organelle fission
|
GO:0048285 |
170 |
0.354
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
89 |
0.352
|
|
|
|
negative regulation of lymphocyte activation
|
GO:0051250 |
91 |
0.348
|
Mouse |
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.346
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
187 |
0.334
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
121 |
0.333
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
184 |
0.332
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
95 |
0.330
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.329
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.327
|
Mouse |
|
|
learning or memory
|
GO:0007611 |
148 |
0.324
|
Fly |
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.323
|
|
|
|
cellular response to interleukin 6
|
GO:0071354 |
9 |
0.321
|
|
|
|
negative regulation of t cell differentiation
|
GO:0045581 |
23 |
0.320
|
Mouse |
|
|
digestive system development
|
GO:0055123 |
200 |
0.314
|
Fly |
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.309
|
Human Rat |
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
126 |
0.308
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
65 |
0.308
|
Mouse |
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.307
|
Mouse |
|
|
regulation of organelle organization
|
GO:0033043 |
289 |
0.307
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.302
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.301
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
139 |
0.300
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
220 |
0.298
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.296
|
Human Rat |
|
|
positive regulation of alpha beta t cell activation
|
GO:0046635 |
39 |
0.296
|
|
|
|
innate immune response
|
GO:0045087 |
157 |
0.295
|
Rat |
|
|
t helper 1 type immune response
|
GO:0042088 |
25 |
0.294
|
Mouse |
|
|
cerebral cortex radial glia guided migration
|
GO:0021801 |
17 |
0.293
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.293
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.293
|
|
|
|
myeloid cell homeostasis
|
GO:0002262 |
114 |
0.289
|
|
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.287
|
Mouse |
|
|
tyrosine phosphorylation of stat protein
|
GO:0007260 |
23 |
0.286
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
163 |
0.286
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.285
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.284
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
89 |
0.283
|
Mouse |
|
|
regulation of peptidase activity
|
GO:0052547 |
96 |
0.282
|
|
|
|
regulation of t helper 2 cell differentiation
|
GO:0045628 |
8 |
0.281
|
|
|
|
regulation of nuclear division
|
GO:0051783 |
56 |
0.280
|
|
|
|
type 2 immune response
|
GO:0042092 |
23 |
0.280
|
|
|
|
apical constriction
|
GO:0003383 |
4 |
0.280
|
Fly |
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.279
|
|
|
|
retina morphogenesis in camera type eye
|
GO:0060042 |
45 |
0.278
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.278
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.273
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.268
|
|
|
|
t helper 2 cell differentiation
|
GO:0045064 |
12 |
0.263
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
62 |
0.262
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.261
|
|
|
|
actin cytoskeleton reorganization
|
GO:0031532 |
21 |
0.261
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
194 |
0.257
|
|
|
|
syncytium formation
|
GO:0006949 |
43 |
0.252
|
|
|
|
multicellular organism growth
|
GO:0035264 |
161 |
0.246
|
|
|
|
response to acid chemical
|
GO:0001101 |
111 |
0.245
|
|
|
|
urogenital system development
|
GO:0001655 |
261 |
0.245
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.243
|
Mouse |
|
|
negative regulation of interferon gamma mediated signaling pathway
|
GO:0060336 |
1 |
0.243
|
|
|
|
skin development
|
GO:0043588 |
220 |
0.242
|
|
|
|
mammary gland morphogenesis
|
GO:0060443 |
54 |
0.242
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
126 |
0.240
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
221 |
0.240
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.239
|
|
|
|
stem cell maintenance
|
GO:0019827 |
130 |
0.239
|
Fly |
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.234
|
|
|
|
leukocyte homeostasis
|
GO:0001776 |
79 |
0.233
|
Mouse |
|
|
epidermis development
|
GO:0008544 |
187 |
0.229
|
|
|
|
regulation of immunoglobulin production
|
GO:0002637 |
42 |
0.225
|
|
|
|
epidermal growth factor receptor signaling pathway
|
GO:0007173 |
28 |
0.223
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
128 |
0.222
|
|
|
|
respiratory system development
|
GO:0060541 |
190 |
0.221
|
Fly |
|
|
response to steroid hormone
|
GO:0048545 |
56 |
0.220
|
|
|
|
body fluid secretion
|
GO:0007589 |
53 |
0.217
|
|
|
|
cation transport
|
GO:0006812 |
399 |
0.215
|
|
|
|
natural killer cell activation
|
GO:0030101 |
44 |
0.206
|
|
|
|
positive regulation of insulin receptor signaling pathway
|
GO:0046628 |
4 |
0.206
|
|
|
|
hindbrain radial glia guided cell migration
|
GO:0021932 |
12 |
0.205
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
93 |
0.205
|
|
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
61 |
0.204
|
|
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
41 |
0.203
|
Fly |
|
|
negative regulation of response to cytokine stimulus
|
GO:0060761 |
9 |
0.201
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.199
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.199
|
Rat |
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.195
|
|
|
|
digestive tract development
|
GO:0048565 |
190 |
0.194
|
Fly |
|
|
camera type eye development
|
GO:0043010 |
266 |
0.194
|
|
|
|
mapk cascade
|
GO:0000165 |
281 |
0.193
|
Rat |
|
|
placenta blood vessel development
|
GO:0060674 |
31 |
0.192
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
87 |
0.191
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
167 |
0.191
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.188
|
Rat |
|
|
negative regulation of t helper 1 cell differentiation
|
GO:0045626 |
3 |
0.188
|
Mouse |
|
|
erbb signaling pathway
|
GO:0038127 |
32 |
0.187
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.185
|
Fly |
|
|
negative regulation of t cell apoptotic process
|
GO:0070233 |
18 |
0.182
|
Mouse |
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
61 |
0.181
|
|
|
|
spongiotrophoblast layer development
|
GO:0060712 |
15 |
0.181
|
|
|
|
interferon gamma mediated signaling pathway
|
GO:0060333 |
5 |
0.178
|
Rat |
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.178
|
|
|
|
lung cell differentiation
|
GO:0060479 |
30 |
0.178
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
207 |
0.176
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.174
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
119 |
0.171
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.170
|
Rat |
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.170
|
|
|
|
interleukin 2 mediated signaling pathway
|
GO:0038110 |
2 |
0.170
|
|
|
|
embryonic placenta development
|
GO:0001892 |
98 |
0.169
|
|
|
|
negative regulation of jak stat cascade
|
GO:0046426 |
7 |
0.167
|
|
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.167
|
Rat |
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
122 |
0.164
|
Rat |
|
|
cellular response to growth hormone stimulus
|
GO:0071378 |
7 |
0.164
|
|
|
|
regulation of cell size
|
GO:0008361 |
72 |
0.162
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.160
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.159
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.159
|
|
|
|
positive regulation of mitotic cell cycle
|
GO:0045931 |
41 |
0.159
|
|
|
|
hematopoietic stem cell migration
|
GO:0035701 |
1 |
0.159
|
|
|
|
negative regulation of type 2 immune response
|
GO:0002829 |
8 |
0.159
|
|
|
|
protein maturation
|
GO:0051604 |
176 |
0.158
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.157
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
159 |
0.157
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.153
|
|
|
|
protein ubiquitination
|
GO:0016567 |
171 |
0.150
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
39 |
0.150
|
|
|
|
leukocyte apoptotic process
|
GO:0071887 |
71 |
0.150
|
Mouse |
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.148
|
Mouse |
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.148
|
|
|
|
dna recombination
|
GO:0006310 |
92 |
0.147
|
|
|
|
negative regulation of alpha beta t cell differentiation
|
GO:0046639 |
12 |
0.146
|
Mouse |
|
|
negative regulation of synaptic vesicle transport
|
GO:1902804 |
3 |
0.145
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.144
|
|
|
|
regulation of mast cell activation
|
GO:0033003 |
21 |
0.143
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.143
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.143
|
Rat |
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.142
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
121 |
0.142
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.142
|
|
|
|
retina development in camera type eye
|
GO:0060041 |
119 |
0.141
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
157 |
0.141
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
85 |
0.140
|
|
|
|
hindbrain development
|
GO:0030902 |
128 |
0.140
|
|
|
|
actin filament organization
|
GO:0007015 |
113 |
0.138
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.137
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.135
|
Rat |
|
|
t cell differentiation in thymus
|
GO:0033077 |
77 |
0.132
|
|
|
|
long term memory
|
GO:0007616 |
15 |
0.132
|
Fly |
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.130
|
Rat |
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.129
|
Rat |
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.129
|
Rat |
|
|
lung development
|
GO:0030324 |
164 |
0.128
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.127
|
|
|
|
cellular response to interleukin 4
|
GO:0071353 |
21 |
0.127
|
|
|
|
rhythmic process
|
GO:0048511 |
174 |
0.125
|
Fly |
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.125
|
Rat |
|
|
t cell homeostasis
|
GO:0043029 |
35 |
0.125
|
Mouse |
|
|
placenta development
|
GO:0001890 |
140 |
0.125
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
48 |
0.123
|
|
|
|
organelle localization
|
GO:0051640 |
179 |
0.123
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
71 |
0.123
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.123
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.122
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.121
|
Rat |
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.121
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.121
|
|
|
|
immunoglobulin mediated immune response
|
GO:0016064 |
69 |
0.120
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
178 |
0.118
|
|
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.117
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.117
|
Rat |
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.117
|
|
|
|
regulation of leukocyte mediated cytotoxicity
|
GO:0001910 |
38 |
0.116
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
147 |
0.116
|
Fly |
|
|
monosaccharide metabolic process
|
GO:0005996 |
106 |
0.116
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
27 |
0.115
|
|
|
|
t cell mediated immunity
|
GO:0002456 |
50 |
0.115
|
|
|
|
regulation of b cell activation
|
GO:0050864 |
81 |
0.115
|
|
|
|
zymogen activation
|
GO:0031638 |
41 |
0.114
|
|
|
|
negative regulation of antigen receptor mediated signaling pathway
|
GO:0050858 |
16 |
0.114
|
|
|
|
immunoglobulin production
|
GO:0002377 |
73 |
0.113
|
|
|
|
lateral line system development
|
GO:0048925 |
1 |
0.113
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
62 |
0.113
|
|
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.113
|
|
|
|
regulation of interferon gamma mediated signaling pathway
|
GO:0060334 |
3 |
0.111
|
|
|
|
t cell apoptotic process
|
GO:0070231 |
39 |
0.109
|
Mouse |
|
|
leukocyte mediated cytotoxicity
|
GO:0001909 |
62 |
0.108
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.106
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.106
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.105
|
|
|
|
negative regulation of cd4 positive alpha beta t cell differentiation
|
GO:0043371 |
9 |
0.105
|
Mouse |
|
|
positive regulation of jak stat cascade
|
GO:0046427 |
22 |
0.105
|
|
|
|
response to alcohol
|
GO:0097305 |
48 |
0.103
|
|
|
|
regulation of t cell receptor signaling pathway
|
GO:0050856 |
21 |
0.103
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.103
|
Rat |
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.102
|
|
|
|
maintenance of location
|
GO:0051235 |
89 |
0.101
|
|
|
|
cellular response to interleukin 15
|
GO:0071350 |
2 |
0.101
|
|
|
|
embryonic hemopoiesis
|
GO:0035162 |
23 |
0.101
|
|
|
|
actin filament based movement
|
GO:0030048 |
23 |
0.100
|
Fly |
|
|
regulation of cytokine secretion
|
GO:0050707 |
61 |
0.100
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.100
|
|
|
|
somatic diversification of immune receptors
|
GO:0002200 |
53 |
0.100
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.099
|
|
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.098
|
|
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.098
|
|
|
|
response to interleukin 4
|
GO:0070670 |
23 |
0.097
|
|
|
|
regulation of b cell differentiation
|
GO:0045577 |
23 |
0.097
|
|
|
|
cerebral cortex radially oriented cell migration
|
GO:0021799 |
31 |
0.096
|
|
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.095
|
Rat |
|
|
regulation of protein processing
|
GO:0070613 |
96 |
0.095
|
|
|
|
endomembrane system organization
|
GO:0010256 |
147 |
0.095
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
130 |
0.094
|
|
|
|
negative regulation of growth
|
GO:0045926 |
99 |
0.094
|
|
|
|
regulation of cell shape
|
GO:0008360 |
39 |
0.094
|
Fly |
|
|
dna biosynthetic process
|
GO:0071897 |
22 |
0.093
|
|
|
|
macromolecule methylation
|
GO:0043414 |
120 |
0.093
|
|
|
|
negative regulation of synaptic vesicle exocytosis
|
GO:2000301 |
3 |
0.093
|
|
|
|
lymphocyte apoptotic process
|
GO:0070227 |
54 |
0.093
|
Mouse |
|
|
forebrain cell migration
|
GO:0021885 |
58 |
0.093
|
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.093
|
|
|
|
regulation of lymphocyte apoptotic process
|
GO:0070228 |
41 |
0.092
|
Mouse |
|
|
interleukin 4 mediated signaling pathway
|
GO:0035771 |
2 |
0.092
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
61 |
0.090
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.090
|
|
|
|
cerebral cortex development
|
GO:0021987 |
86 |
0.089
|
|
|
|
b cell mediated immunity
|
GO:0019724 |
71 |
0.089
|
|
|
|
columnar cuboidal epithelial cell differentiation
|
GO:0002065 |
82 |
0.089
|
Fly |
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.089
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.087
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.086
|
|
|
|
regulation of response to cytokine stimulus
|
GO:0060759 |
23 |
0.086
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.086
|
Rat |
|
|
response to interleukin 2
|
GO:0070669 |
2 |
0.086
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
52 |
0.086
|
Fly |
|
|
generation of precursor metabolites and energy
|
GO:0006091 |
103 |
0.086
|
|
|
|
regulation of mast cell proliferation
|
GO:0070666 |
4 |
0.086
|
|
|
|
mammary gland alveolus development
|
GO:0060749 |
22 |
0.086
|
|
|
|
hematopoietic progenitor cell differentiation
|
GO:0002244 |
143 |
0.085
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.085
|
|
|
|
nuclear import
|
GO:0051170 |
95 |
0.085
|
|
|
|
activation of jak2 kinase activity
|
GO:0042977 |
2 |
0.084
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
293 |
0.084
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
92 |
0.084
|
|
|
|
t cell selection
|
GO:0045058 |
34 |
0.084
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
71 |
0.084
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.083
|
Rat |
|
|
regulation of t cell differentiation in thymus
|
GO:0033081 |
24 |
0.083
|
|
|
|
telencephalon cell migration
|
GO:0022029 |
55 |
0.083
|
|
|
|
cell differentiation involved in embryonic placenta development
|
GO:0060706 |
26 |
0.083
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
96 |
0.083
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
77 |
0.083
|
Mouse |
|
|
labyrinthine layer development
|
GO:0060711 |
49 |
0.083
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
69 |
0.082
|
|
|
|
dendritic cell apoptotic process
|
GO:0097048 |
3 |
0.082
|
Mouse |
|
|
positive regulation of growth hormone receptor signaling pathway
|
GO:0060399 |
3 |
0.082
|
|
|
|
carbohydrate homeostasis
|
GO:0033500 |
128 |
0.082
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
141 |
0.081
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.081
|
Rat |
|
|
lung epithelium development
|
GO:0060428 |
37 |
0.080
|
|
|
|
b cell proliferation
|
GO:0042100 |
53 |
0.080
|
|
|
|
positive regulation of adaptive immune response
|
GO:0002821 |
61 |
0.080
|
|
|
|
mammary gland lobule development
|
GO:0061377 |
22 |
0.079
|
|
|
|
regulation of cell division
|
GO:0051302 |
76 |
0.079
|
|
|
|
regulation of protein tyrosine kinase activity
|
GO:0061097 |
17 |
0.077
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.077
|
|
|
|
pallium development
|
GO:0021543 |
120 |
0.077
|
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.077
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
38 |
0.076
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
144 |
0.076
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.076
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
79 |
0.076
|
|
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.076
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
43 |
0.076
|
|
|
|
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002823 |
23 |
0.075
|
Mouse |
|
|
mast cell proliferation
|
GO:0070662 |
4 |
0.075
|
|
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.075
|
|
|
|
regulation of mitosis
|
GO:0007088 |
29 |
0.075
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.074
|
|
|
|
sensory system development
|
GO:0048880 |
3 |
0.073
|
|
|
|
glucose homeostasis
|
GO:0042593 |
128 |
0.073
|
|
|
|
response to progesterone
|
GO:0032570 |
1 |
0.073
|
|
|
|
protein targeting
|
GO:0006605 |
143 |
0.072
|
|
|
|
gliogenesis
|
GO:0042063 |
141 |
0.072
|
|
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.071
|
Fly |
|
|
regeneration
|
GO:0031099 |
38 |
0.070
|
Rat |
|
|
lateral inhibition
|
GO:0046331 |
1 |
0.070
|
|
|
|
somatic cell dna recombination
|
GO:0016444 |
51 |
0.070
|
|
|
|
positive regulation of t helper cell differentiation
|
GO:0045624 |
9 |
0.070
|
|
|
|
male gamete generation
|
GO:0048232 |
285 |
0.070
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
107 |
0.069
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.069
|
|
|
|
protein import
|
GO:0017038 |
101 |
0.068
|
|
|
|
positive regulation of gamma delta t cell differentiation
|
GO:0045588 |
6 |
0.068
|
|
|
|
histone modification
|
GO:0016570 |
159 |
0.068
|
Human |
|
|
cellular response to granulocyte macrophage colony stimulating factor stimulus
|
GO:0097011 |
3 |
0.068
|
|
|
|
regulation of response to interferon gamma
|
GO:0060330 |
3 |
0.068
|
|
|
|
cerebral cortex cell migration
|
GO:0021795 |
44 |
0.068
|
|
|
|
extracellular structure organization
|
GO:0043062 |
148 |
0.067
|
|
|
|
response to granulocyte macrophage colony stimulating factor
|
GO:0097012 |
3 |
0.067
|
|
|
|
sulfur compound metabolic process
|
GO:0006790 |
100 |
0.066
|
|
|
|
leukocyte degranulation
|
GO:0043299 |
27 |
0.066
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
181 |
0.066
|
|
|
|
platelet aggregation
|
GO:0070527 |
20 |
0.066
|
|
|
|
regulation of mast cell activation involved in immune response
|
GO:0033006 |
17 |
0.066
|
|
|
|
liver development
|
GO:0001889 |
66 |
0.066
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
27 |
0.066
|
|
|
|
single organism nuclear import
|
GO:1902593 |
95 |
0.065
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.065
|
Rat |
|
|
negative regulation of t cell mediated cytotoxicity
|
GO:0001915 |
3 |
0.065
|
|
|
|
type i interferon signaling pathway
|
GO:0060337 |
10 |
0.064
|
|
|
|
b cell homeostasis
|
GO:0001782 |
34 |
0.064
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.064
|
|
|
|
branching involved in labyrinthine layer morphogenesis
|
GO:0060670 |
9 |
0.063
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
138 |
0.063
|
Rat |
|
|
blastocyst development
|
GO:0001824 |
80 |
0.062
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
40 |
0.062
|
|
|
|
synaptic vesicle localization
|
GO:0097479 |
59 |
0.062
|
|
|
|
convergent extension
|
GO:0060026 |
14 |
0.062
|
Fly |
|
|
embryonic placenta morphogenesis
|
GO:0060669 |
25 |
0.061
|
|
