Mus musculus

0 known processes

Kars

lysyl-tRNA synthetase

(Aliases: AL024334,LysRS,AL033367,AL033315,AA589550,D8Ertd698e,mKIAA0070,D8Wsu108e)

Kars biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nuclear division GO:0000280 158 0.297
alpha amino acid biosynthetic process GO:1901607 15 0.193
oocyte anterior posterior axis specification GO:0007314 2 0.191
snrna processing GO:0016180 1 0.161
rna processing GO:0006396 105 0.159
positive regulation of apoptotic process GO:0043065 217 0.127
pole plasm assembly GO:0007315 2 0.124
mrna processing GO:0006397 63 0.099
mrna metabolic process GO:0016071 84 0.096
apoptotic signaling pathway GO:0097190 306 0.096
mrna splicing via spliceosome GO:0000398 43 0.095
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.091
purine nucleoside catabolic process GO:0006152 205 0.087
intrinsic apoptotic signaling pathway GO:0097193 132 0.086
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 43 0.086
oogenesis GO:0048477 56 0.081
nucleoside phosphate catabolic process GO:1901292 222 0.080
microtubule cytoskeleton organization GO:0000226 157 0.077
intracellular mrna localization GO:0008298 4 0.075
purine containing compound metabolic process GO:0072521 311 0.074
aromatic compound catabolic process GO:0019439 286 0.072
nucleotide metabolic process GO:0009117 332 0.072
rna splicing GO:0008380 54 0.070
nucleoside catabolic process GO:0009164 206 0.069
snrna metabolic process GO:0016073 1 0.069
positive regulation of apoptotic signaling pathway GO:2001235 95 0.069
ribonucleotide metabolic process GO:0009259 291 0.064
purine nucleoside triphosphate catabolic process GO:0009146 203 0.063
rna splicing via transesterification reactions GO:0000375 43 0.062
nucleoside phosphate metabolic process GO:0006753 338 0.062
germ cell development GO:0007281 185 0.061
purine nucleoside monophosphate metabolic process GO:0009126 81 0.061
spindle assembly involved in mitosis GO:0090307 4 0.060
cellular response to dna damage stimulus GO:0006974 207 0.060
regulation of cell migration GO:0030334 219 0.060
circadian regulation of gene expression GO:0032922 48 0.060
nucleoside monophosphate metabolic process GO:0009123 85 0.059
negative regulation of intracellular signal transduction GO:1902532 167 0.057
meiotic nuclear division GO:0007126 115 0.055
cell division GO:0051301 120 0.054
purine nucleoside monophosphate catabolic process GO:0009128 58 0.054
oocyte axis specification GO:0007309 2 0.053
ribose phosphate metabolic process GO:0019693 291 0.049
organelle fission GO:0048285 170 0.049
glycosyl compound metabolic process GO:1901657 246 0.047
cytoplasmic transport GO:0016482 234 0.047
regulation of cell cycle process GO:0010564 160 0.046
nucleotide catabolic process GO:0009166 217 0.046
atp catabolic process GO:0006200 55 0.045
negative regulation of dna damage response signal transduction by p53 class mediator GO:0043518 5 0.044
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.043
toxin transport GO:1901998 38 0.042
positive regulation of cell death GO:0010942 224 0.041
purine ribonucleoside catabolic process GO:0046130 205 0.040
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.040
oocyte construction GO:0007308 2 0.039
nucleoside monophosphate catabolic process GO:0009125 59 0.038
nucleoside triphosphate metabolic process GO:0009141 230 0.038
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.037
peptidyl lysine modification GO:0018205 77 0.036
regulation of cell motility GO:2000145 236 0.035
carbohydrate derivative catabolic process GO:1901136 231 0.035
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.035
purine containing compound catabolic process GO:0072523 213 0.034
chromatin modification GO:0016568 187 0.034
heterocycle catabolic process GO:0046700 280 0.033
chromatin organization GO:0006325 206 0.033
glycosyl compound catabolic process GO:1901658 206 0.032
ribonucleoside triphosphate catabolic process GO:0009203 199 0.031
maternal determination of anterior posterior axis embryo GO:0008358 2 0.031
mitotic nuclear division GO:0007067 48 0.031
sperm egg recognition GO:0035036 37 0.031
regulation of cell division GO:0051302 76 0.031
purine nucleotide metabolic process GO:0006163 302 0.030
translation GO:0006412 93 0.030
Yeast
regulation of inflammatory response GO:0050727 147 0.029
ribonucleotide catabolic process GO:0009261 208 0.028
rna localization GO:0006403 23 0.028
purine ribonucleoside monophosphate metabolic process GO:0009167 80 0.028
blastocyst development GO:0001824 80 0.028
ribonucleoside monophosphate metabolic process GO:0009161 80 0.028
cell adhesion GO:0007155 329 0.028
lateral inhibition GO:0046331 1 0.028
endocytosis GO:0006897 168 0.027
peptidyl amino acid modification GO:0018193 336 0.027
mitochondrial translation GO:0032543 4 0.027
microtubule based process GO:0007017 236 0.026
positive regulation of programmed cell death GO:0043068 218 0.025
ribonucleoside catabolic process GO:0042454 206 0.025
purine nucleoside triphosphate metabolic process GO:0009144 226 0.025
cellular response to lipid GO:0071396 145 0.025
regulation of defense response GO:0031347 233 0.024
regulation of rna splicing GO:0043484 37 0.024
translational initiation GO:0006413 24 0.023
chromosome separation GO:0051304 14 0.023
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.023
regulation of cellular response to stress GO:0080135 159 0.022
purine nucleoside metabolic process GO:0042278 241 0.022
leukocyte apoptotic process GO:0071887 71 0.022
atp metabolic process GO:0046034 75 0.022
purine ribonucleotide metabolic process GO:0009150 290 0.022
ribonucleoside monophosphate catabolic process GO:0009158 57 0.022
translesion synthesis GO:0019985 1 0.022
dna repair GO:0006281 107 0.022
regulation of response to wounding GO:1903034 189 0.021
protein desumoylation GO:0016926 2 0.021
male gamete generation GO:0048232 285 0.021
regulation of mrna metabolic process GO:1903311 43 0.021
protein localization to nucleus GO:0034504 121 0.021
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.020
ribonucleoside metabolic process GO:0009119 245 0.020
purine ribonucleotide catabolic process GO:0009154 208 0.020
organophosphate catabolic process GO:0046434 232 0.020
regulation of wnt signaling pathway GO:0030111 123 0.020
cellular response to sterol GO:0036315 2 0.020
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 34 0.020
regulation of mrna processing GO:0050684 41 0.020
positive regulation of cytokine production GO:0001819 174 0.020
organic cyclic compound catabolic process GO:1901361 295 0.020
multi multicellular organism process GO:0044706 109 0.019
regulation of mrna splicing via spliceosome GO:0048024 32 0.019
regulation of intracellular transport GO:0032386 159 0.019
positive regulation of protein modification process GO:0031401 299 0.019
protein alkylation GO:0008213 81 0.019
covalent chromatin modification GO:0016569 163 0.019
response to acid chemical GO:0001101 111 0.019
response to light stimulus GO:0009416 135 0.019
organonitrogen compound catabolic process GO:1901565 264 0.019
nucleobase containing small molecule metabolic process GO:0055086 352 0.018
nucleoside triphosphate catabolic process GO:0009143 205 0.018
snrna 3 end processing GO:0034472 1 0.018
maintenance of location GO:0051235 89 0.018
purine nucleotide catabolic process GO:0006195 211 0.017
response to organic cyclic compound GO:0014070 198 0.017
regulation of transferase activity GO:0051338 263 0.017
mitotic cell cycle process GO:1903047 159 0.017
macromolecule catabolic process GO:0009057 281 0.017
reactive nitrogen species metabolic process GO:2001057 0 0.017
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.017
carboxylic acid catabolic process GO:0046395 51 0.017
protein methylation GO:0006479 81 0.017
cytoplasmic microtubule organization GO:0031122 14 0.017
regulation of apoptotic signaling pathway GO:2001233 197 0.016
organelle assembly GO:0070925 177 0.016
inflammatory response GO:0006954 244 0.016
response to organonitrogen compound GO:0010243 246 0.016
protein localization to organelle GO:0033365 185 0.016
histone modification GO:0016570 159 0.016
inflammatory cell apoptotic process GO:0006925 11 0.016
regulation of cell cycle GO:0051726 281 0.016
spindle organization GO:0007051 28 0.016
regulation of cytokine production GO:0001817 266 0.015
spermatogenesis GO:0007283 284 0.015
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000466 1 0.015
carbohydrate metabolic process GO:0005975 230 0.015
wnt signaling pathway GO:0016055 188 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.015
histone acetylation GO:0016573 41 0.015
epithelial tube morphogenesis GO:0060562 303 0.015
purine ribonucleoside metabolic process GO:0046128 241 0.015
ribonucleoside triphosphate metabolic process GO:0009199 220 0.015
nucleoside metabolic process GO:0009116 246 0.015
rna transport GO:0050658 18 0.015
nucleic acid transport GO:0050657 18 0.014
single organism cell adhesion GO:0098602 156 0.014
positive regulation of cell migration GO:0030335 109 0.014
protein processing GO:0016485 163 0.014
ncrna 3 end processing GO:0043628 2 0.014
dna damage response signal transduction by p53 class mediator GO:0030330 19 0.014
hormone metabolic process GO:0042445 86 0.014
sister chromatid cohesion GO:0007062 12 0.014
cellular macromolecule catabolic process GO:0044265 206 0.014
nitrogen compound transport GO:0071705 271 0.014
transcription from rna polymerase iii promoter GO:0006383 3 0.014
mrna transport GO:0051028 13 0.013
ion transmembrane transport GO:0034220 361 0.013
fertilization GO:0009566 127 0.013
dna metabolic process GO:0006259 303 0.013
muscle cell development GO:0055001 133 0.013
methylation GO:0032259 134 0.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.013
macromolecule methylation GO:0043414 120 0.013
alpha amino acid metabolic process GO:1901605 59 0.013
cell cell recognition GO:0009988 44 0.013
organic acid biosynthetic process GO:0016053 86 0.013
chromosome segregation GO:0007059 48 0.013
regulation of mitotic sister chromatid segregation GO:0033047 12 0.013
nucleocytoplasmic transport GO:0006913 139 0.013
cellular protein complex assembly GO:0043623 116 0.013
lipid localization GO:0010876 126 0.013
positive regulation of mitotic cell cycle GO:0045931 41 0.012
immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 43 0.012
developmental maturation GO:0021700 193 0.012
response to radiation GO:0009314 165 0.012
regulation of leukocyte apoptotic process GO:2000106 56 0.012
cellular response to cytokine stimulus GO:0071345 189 0.012
nuclear transport GO:0051169 139 0.012
positive regulation of defense response GO:0031349 124 0.012
modification dependent macromolecule catabolic process GO:0043632 133 0.012
cellular nitrogen compound catabolic process GO:0044270 280 0.012
negative regulation of molecular function GO:0044092 258 0.012
signal transduction by p53 class mediator GO:0072331 51 0.012
multicellular organismal aging GO:0010259 24 0.011
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 35 0.011
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.011
nucleobase containing compound transport GO:0015931 27 0.011
positive regulation of immune effector process GO:0002699 107 0.011
histone methylation GO:0016571 71 0.011
cellular amino acid biosynthetic process GO:0008652 22 0.011
regulation of cell activation GO:0050865 289 0.011
regulation of interferon gamma production GO:0032649 57 0.011
striated muscle tissue development GO:0014706 293 0.011
oocyte differentiation GO:0009994 35 0.011
single fertilization GO:0007338 82 0.010
cellular protein catabolic process GO:0044257 155 0.010
transmembrane transport GO:0055085 412 0.010
mitotic spindle organization GO:0007052 10 0.010
rna export from nucleus GO:0006405 15 0.010
mesenchymal cell development GO:0014031 93 0.010
granulocyte macrophage colony stimulating factor production GO:0032604 3 0.010
immunoglobulin mediated immune response GO:0016064 69 0.010
glutamate biosynthetic process GO:0006537 2 0.010
regulation of protein catabolic process GO:0042176 108 0.010
endothelial cell activation GO:0042118 1 0.010
cell maturation GO:0048469 127 0.010
regulation of cell adhesion GO:0030155 154 0.010
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 1 0.010
positive regulation of cellular amine metabolic process GO:0033240 5 0.010
positive regulation of activin receptor signaling pathway GO:0032927 3 0.010
interferon gamma production GO:0032609 67 0.010
aspartate family amino acid metabolic process GO:0009066 10 0.010
placenta development GO:0001890 140 0.010
leukocyte proliferation GO:0070661 172 0.010

Kars disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.063
central nervous system disease DOID:331 0 0.063
nervous system disease DOID:863 0 0.063
neurodegenerative disease DOID:1289 0 0.024
retinal disease DOID:5679 0 0.020
sensory system disease DOID:0050155 0 0.020
eye and adnexa disease DOID:1492 0 0.020
eye disease DOID:5614 0 0.020
inherited metabolic disorder DOID:655 0 0.016
disease of metabolism DOID:0014667 0 0.016
retinal degeneration DOID:8466 0 0.014
glaucoma DOID:1686 0 0.014
disease of cellular proliferation DOID:14566 0 0.011
cancer DOID:162 0 0.011