Mus musculus

19 known processes

Kcna2

potassium voltage-gated channel, shaker-related subfamily, member 2

(Aliases: Akr6a4,Kv1.2,Mk-2,Kca1-2)

Kcna2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of membrane potential GO:0042391 192 0.983
Mouse Fly
ion transmembrane transport GO:0034220 361 0.962
Mouse Fly
neuronal action potential GO:0019228 54 0.961
regulation of ion transport GO:0043269 215 0.952
Mouse Fly
cation transport GO:0006812 399 0.946
Mouse Fly
action potential GO:0001508 78 0.945
Mouse Fly
multicellular organismal signaling GO:0035637 91 0.927
cellular potassium ion transport GO:0071804 43 0.918
Mouse
transmembrane transport GO:0055085 412 0.916
Mouse Fly
regulation of system process GO:0044057 200 0.903
Mouse
circulatory system process GO:0003013 197 0.902
Mouse
potassium ion transport GO:0006813 52 0.862
Mouse
inorganic ion transmembrane transport GO:0098660 234 0.846
Mouse
blood circulation GO:0008015 195 0.844
Mouse
cranial nerve structural organization GO:0021604 13 0.836
g protein coupled receptor signaling pathway GO:0007186 243 0.817
regulation of cell motility GO:2000145 236 0.816
synaptic transmission GO:0007268 329 0.811
Fly
mating behavior sex discrimination GO:0048047 1 0.802
Fly
potassium ion transmembrane transport GO:0071805 43 0.781
Mouse
inorganic cation transmembrane transport GO:0098662 207 0.774
Mouse
vascular process in circulatory system GO:0003018 62 0.774
Mouse
transmission of nerve impulse GO:0019226 76 0.760
regulation of potassium ion transport GO:0043266 16 0.750
Mouse
anatomical structure arrangement GO:0048532 20 0.738
negative regulation of potassium ion transport GO:0043267 7 0.723
Mouse
ensheathment of neurons GO:0007272 76 0.709
glial cell development GO:0021782 54 0.680
calcium ion transport GO:0006816 159 0.637
g protein coupled receptor internalization GO:0002031 3 0.636
regulation of muscle system process GO:0090257 80 0.631
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.627
Fly
regulation of neurotransmitter levels GO:0001505 87 0.615
regulation of blood circulation GO:1903522 93 0.610
Mouse
camp biosynthetic process GO:0006171 31 0.604
locomotory behavior GO:0007626 195 0.603
Fly
regulation of cell migration GO:0030334 219 0.601
cation homeostasis GO:0055080 212 0.600
cation transmembrane transport GO:0098655 266 0.585
Mouse Fly
purine nucleotide biosynthetic process GO:0006164 65 0.584
phenol containing compound metabolic process GO:0018958 60 0.581
regulation of purine nucleotide biosynthetic process GO:1900371 34 0.569
regulation of heart contraction GO:0008016 77 0.568
positive regulation of cell migration GO:0030335 109 0.568
positive regulation of nucleotide biosynthetic process GO:0030810 26 0.545
regulation of hydrolase activity GO:0051336 246 0.531
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway GO:0051482 4 0.531
response to radiation GO:0009314 165 0.529
Fly
cellular metal ion homeostasis GO:0006875 151 0.525
second messenger mediated signaling GO:0019932 73 0.525
neurotransmitter transport GO:0006836 76 0.515
activation of adenylate cyclase activity GO:0007190 4 0.515
glial cell differentiation GO:0010001 131 0.514
regulation of neuron differentiation GO:0045664 281 0.509
axon ensheathment GO:0008366 76 0.508
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.492
regulation of cell projection organization GO:0031344 206 0.492
regulation of metal ion transport GO:0010959 106 0.490
Mouse
metal ion homeostasis GO:0055065 189 0.484
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.481
central nervous system neuron differentiation GO:0021953 162 0.474
regulation of neurotransmitter transport GO:0051588 35 0.462
regulation of circadian sleep wake cycle GO:0042749 3 0.459
Fly
blood vessel morphogenesis GO:0048514 285 0.454
response to amphetamine GO:0001975 16 0.453
immune effector process GO:0002252 321 0.451
regulation of muscle contraction GO:0006937 49 0.450
heart contraction GO:0060047 93 0.449
cellular homeostasis GO:0019725 240 0.445
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 24 0.444
cyclic purine nucleotide metabolic process GO:0052652 43 0.436
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 26 0.429
neuromuscular process GO:0050905 99 0.427
regulation of transmembrane transport GO:0034762 128 0.421
Mouse Fly
cellular response to lipid GO:0071396 145 0.409
myelination GO:0042552 74 0.402
cyclic nucleotide biosynthetic process GO:0009190 44 0.396
leukocyte differentiation GO:0002521 342 0.396
positive regulation of growth GO:0045927 104 0.394
organophosphate biosynthetic process GO:0090407 122 0.392
multicellular organismal homeostasis GO:0048871 164 0.391
learning or memory GO:0007611 148 0.391
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.389
regulation of transferase activity GO:0051338 263 0.381
axonogenesis GO:0007409 274 0.378
Fly
muscle cell differentiation GO:0042692 261 0.377
multicellular organism growth GO:0035264 161 0.372
regulation of g protein coupled receptor protein signaling pathway GO:0008277 37 0.370
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.370
asymmetric stem cell division GO:0098722 3 0.369
positive regulation of camp metabolic process GO:0030816 19 0.362
synaptic transmission glutamatergic GO:0035249 36 0.360
associative learning GO:0008306 61 0.358
l amino acid transport GO:0015807 32 0.353
positive regulation of glycolytic process GO:0045821 4 0.351
cellular chemical homeostasis GO:0055082 215 0.351
organonitrogen compound biosynthetic process GO:1901566 192 0.348
optic nerve structural organization GO:0021633 2 0.345
ribonucleotide biosynthetic process GO:0009260 59 0.344
organic hydroxy compound metabolic process GO:1901615 203 0.344
divalent metal ion transport GO:0070838 172 0.341
adult locomotory behavior GO:0008344 91 0.336
Fly
forebrain development GO:0030900 302 0.334
gland development GO:0048732 330 0.330
circadian sleep wake cycle GO:0042745 5 0.329
Fly
regionalization GO:0003002 337 0.328
purine ribonucleotide biosynthetic process GO:0009152 59 0.327
long term synaptic potentiation GO:0060291 25 0.327
cellular calcium ion homeostasis GO:0006874 119 0.325
regulation of blood vessel size GO:0050880 56 0.324
Mouse
regulation of systemic arterial blood pressure by norepinephrine epinephrine GO:0001993 8 0.319
angiogenesis GO:0001525 201 0.315
myelination in peripheral nervous system GO:0022011 19 0.315
response to organic cyclic compound GO:0014070 198 0.311
ribose phosphate biosynthetic process GO:0046390 59 0.310
regulation of body fluid levels GO:0050878 162 0.309
cellular ion homeostasis GO:0006873 165 0.308
gliogenesis GO:0042063 141 0.305
regulation of ion transmembrane transport GO:0034765 119 0.303
Mouse Fly
regulation of homeostatic process GO:0032844 182 0.299
muscle tissue development GO:0060537 308 0.298
sensory perception GO:0007600 245 0.295
regulation of tube size GO:0035150 57 0.294
Mouse
sensory perception of chemical stimulus GO:0007606 51 0.292
bone resorption GO:0045453 38 0.287
positive regulation of cyclic nucleotide metabolic process GO:0030801 24 0.280
adult behavior GO:0030534 135 0.278
Fly
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 30 0.276
vasodilation by norepinephrine epinephrine involved in regulation of systemic arterial blood pressure GO:0002025 3 0.276
positive regulation of heart rate by epinephrine norepinephrine GO:0001996 4 0.274
positive regulation of purine nucleotide biosynthetic process GO:1900373 26 0.270
cardiac muscle contraction GO:0060048 32 0.270
heart process GO:0003015 94 0.269
directional locomotion GO:0033058 3 0.267
dopamine metabolic process GO:0042417 23 0.266
carbohydrate derivative biosynthetic process GO:1901137 183 0.266
sensitization GO:0046960 2 0.264
behavioral response to nutrient GO:0051780 1 0.264
Fly
regulation of camp metabolic process GO:0030814 30 0.262
nucleoside phosphate biosynthetic process GO:1901293 79 0.261
muscle system process GO:0003012 141 0.259
divalent inorganic cation transport GO:0072511 178 0.258
nitrogen compound transport GO:0071705 271 0.257
response to growth factor GO:0070848 198 0.257
regulation of cardiac muscle contraction GO:0055117 21 0.256
regulation of nucleotide metabolic process GO:0006140 169 0.256
regulation of camp biosynthetic process GO:0030817 25 0.256
purine containing compound biosynthetic process GO:0072522 70 0.255
operant conditioning GO:0035106 2 0.255
detection of external stimulus GO:0009581 61 0.255
Fly
purine containing compound metabolic process GO:0072521 311 0.253
neurotransmitter secretion GO:0007269 62 0.251
regulation of t cell activation GO:0050863 170 0.250
regulation of neuron projection development GO:0010975 169 0.250
anatomical structure homeostasis GO:0060249 145 0.248
wound healing GO:0042060 157 0.246
regulation of secretion by cell GO:1903530 249 0.246
developmental maturation GO:0021700 193 0.246
negative regulation of molecular function GO:0044092 258 0.244
regulation of gtp catabolic process GO:0033124 113 0.244
purine nucleoside catabolic process GO:0006152 205 0.242
relaxation of muscle GO:0090075 18 0.241
camp mediated signaling GO:0019933 15 0.240
vasoconstriction GO:0042310 27 0.239
Mouse
digestive tract development GO:0048565 190 0.238
membrane depolarization GO:0051899 64 0.237
chemotaxis GO:0006935 247 0.237
conditioned taste aversion GO:0001661 4 0.237
striated muscle tissue development GO:0014706 293 0.234
oligodendrocyte differentiation GO:0048709 53 0.234
calcium ion homeostasis GO:0055074 127 0.233
learning GO:0007612 98 0.232
positive regulation of leukocyte differentiation GO:1902107 86 0.232
axon guidance GO:0007411 141 0.230
organic hydroxy compound transport GO:0015850 93 0.229
regulation of kinase activity GO:0043549 249 0.228
hormone secretion GO:0046879 128 0.222
regulation of cyclic nucleotide biosynthetic process GO:0030802 31 0.219
catecholamine metabolic process GO:0006584 30 0.217
male gamete generation GO:0048232 285 0.216
negative regulation of phosphate metabolic process GO:0045936 184 0.215
nerve development GO:0021675 67 0.213
negative regulation of ion transport GO:0043271 28 0.212
Mouse
striated muscle cell development GO:0055002 125 0.211
membrane organization GO:0061024 245 0.209
dopamine transport GO:0015872 15 0.209
negative regulation of growth GO:0045926 99 0.206
detection of visible light GO:0009584 14 0.205
Fly
ribonucleotide catabolic process GO:0009261 208 0.205
regulation of cell activation GO:0050865 289 0.204
nucleoside phosphate metabolic process GO:0006753 338 0.203
phospholipase c activating dopamine receptor signaling pathway GO:0060158 5 0.202
regulation of nucleotide biosynthetic process GO:0030808 34 0.202
cytosolic calcium ion homeostasis GO:0051480 70 0.201
skeletal muscle fiber development GO:0048741 58 0.196
negative regulation of cell proliferation GO:0008285 296 0.196
morphogenesis of a branching epithelium GO:0061138 193 0.195
calcium ion transmembrane transport GO:0070588 85 0.195
vasodilation GO:0042311 28 0.193
cellular carbohydrate metabolic process GO:0044262 119 0.193
response to light stimulus GO:0009416 135 0.193
Fly
positive regulation of cell activation GO:0050867 158 0.192
erk1 and erk2 cascade GO:0070371 77 0.191
hemostasis GO:0007599 78 0.191
serotonin receptor signaling pathway GO:0007210 8 0.190
regulation of leukocyte differentiation GO:1902105 159 0.189
sensory perception of mechanical stimulus GO:0050954 107 0.189
positive regulation of cell death GO:0010942 224 0.187
exocytosis GO:0006887 121 0.186
guanosine containing compound metabolic process GO:1901068 144 0.184
potassium ion homeostasis GO:0055075 4 0.184
negative regulation of phosphorus metabolic process GO:0010563 184 0.183
microtubule cytoskeleton organization GO:0000226 157 0.181
response to organonitrogen compound GO:0010243 246 0.180
gtp metabolic process GO:0046039 144 0.180
nucleotide catabolic process GO:0009166 217 0.180
amine metabolic process GO:0009308 45 0.174
regulation of dopamine metabolic process GO:0042053 10 0.174
amino acid transport GO:0006865 61 0.173
cellular response to temperature stimulus GO:0071502 2 0.171
spermatogenesis GO:0007283 284 0.171
regulation of cellular catabolic process GO:0031329 242 0.168
dopamine receptor signaling pathway GO:0007212 16 0.168
endocrine system development GO:0035270 98 0.166
osteoclast differentiation GO:0030316 62 0.165
regulation of lymphocyte activation GO:0051249 240 0.163
skin development GO:0043588 220 0.163
positive regulation of protein phosphorylation GO:0001934 242 0.161
regulation of cellular ketone metabolic process GO:0010565 66 0.160
lymphocyte differentiation GO:0030098 242 0.159
adenylate cyclase inhibiting g protein coupled receptor signaling pathway GO:0007193 20 0.158
sequestering of metal ion GO:0051238 19 0.158
tissue remodeling GO:0048771 102 0.157
telencephalon development GO:0021537 186 0.156
divalent inorganic cation homeostasis GO:0072507 138 0.156
regulation of purine nucleotide catabolic process GO:0033121 122 0.156
cellular amino acid metabolic process GO:0006520 103 0.156
ras protein signal transduction GO:0007265 77 0.155
neuron projection guidance GO:0097485 141 0.155
epidermis development GO:0008544 187 0.154
cellular divalent inorganic cation homeostasis GO:0072503 127 0.153
fat cell differentiation GO:0045444 160 0.153
adult walking behavior GO:0007628 41 0.152
nucleobase containing small molecule metabolic process GO:0055086 352 0.152
immune response activating signal transduction GO:0002757 116 0.150
striated muscle hypertrophy GO:0014897 24 0.149
regulation of hormone levels GO:0010817 211 0.149
protein localization to nucleus GO:0034504 121 0.148
regulation of postsynaptic membrane potential GO:0060078 48 0.148
regulation of anatomical structure size GO:0090066 178 0.148
Mouse
feeding behavior GO:0007631 62 0.148
regulation of neurotransmitter secretion GO:0046928 29 0.146
regulation of purine nucleotide metabolic process GO:1900542 169 0.146
positive regulation of the force of heart contraction by chemical signal GO:0003099 3 0.145
cell maturation GO:0048469 127 0.145
visual learning GO:0008542 44 0.144
bone remodeling GO:0046849 53 0.144
hindbrain development GO:0030902 128 0.144
positive regulation of heart rate GO:0010460 10 0.144
regulation of cyclase activity GO:0031279 13 0.143
cranial nerve development GO:0021545 41 0.143
positive regulation of cell motility GO:2000147 116 0.143
carbohydrate transport GO:0008643 62 0.143
positive regulation of t cell activation GO:0050870 101 0.142
regulation of protein kinase activity GO:0045859 232 0.142
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.142
sensory perception of light stimulus GO:0050953 54 0.141
ribose phosphate metabolic process GO:0019693 291 0.140
cyclic nucleotide metabolic process GO:0009187 59 0.139
regulation of protein localization GO:0032880 231 0.139
positive regulation of mapk cascade GO:0043410 170 0.139
reflex GO:0060004 22 0.139
Fly
skeletal system development GO:0001501 356 0.138
positive regulation of endothelial cell proliferation GO:0001938 17 0.138
positive regulation of camp biosynthetic process GO:0030819 19 0.136
positive regulation of cellular amine metabolic process GO:0033240 5 0.135
positive regulation of cell development GO:0010720 237 0.134
regulation of carbohydrate metabolic process GO:0006109 75 0.134
purine nucleoside triphosphate metabolic process GO:0009144 226 0.134
platelet activation GO:0030168 40 0.134
regulation of mapk cascade GO:0043408 248 0.133
regulation of ion homeostasis GO:2000021 64 0.133
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.132
regulation of cell adhesion GO:0030155 154 0.131
muscle hypertrophy GO:0014896 24 0.130
regulation of protein serine threonine kinase activity GO:0071900 157 0.130
myeloid cell differentiation GO:0030099 233 0.130
ameboidal type cell migration GO:0001667 128 0.130
phospholipase c activating serotonin receptor signaling pathway GO:0007208 1 0.130
purine ribonucleoside metabolic process GO:0046128 241 0.129
t cell proliferation GO:0042098 120 0.129
optic nerve morphogenesis GO:0021631 6 0.129
camp metabolic process GO:0046058 40 0.129
adrenergic receptor signaling pathway GO:0071875 13 0.128
ossification GO:0001503 216 0.128
regulation of ras gtpase activity GO:0032318 88 0.127
urogenital system development GO:0001655 261 0.127
forebrain generation of neurons GO:0021872 63 0.127
innate immune response GO:0045087 157 0.127
activation of immune response GO:0002253 138 0.127
optic nerve development GO:0021554 8 0.126
neuron migration GO:0001764 122 0.125
purine nucleoside metabolic process GO:0042278 241 0.125
neurotransmitter uptake GO:0001504 14 0.125
ear morphogenesis GO:0042471 118 0.124
aromatic compound catabolic process GO:0019439 286 0.124
histamine induced gastric acid secretion GO:0001697 1 0.123
positive regulation of transferase activity GO:0051347 167 0.123
purine containing compound catabolic process GO:0072523 213 0.122
organonitrogen compound catabolic process GO:1901565 264 0.122
epithelial tube morphogenesis GO:0060562 303 0.121
positive regulation of adenylate cyclase activity GO:0045762 8 0.120
negative regulation of homeostatic process GO:0032845 71 0.120
renal system development GO:0072001 225 0.120
neuron projection extension GO:1990138 64 0.120
Fly
regulation of muscle tissue development GO:1901861 97 0.120
serotonin metabolic process GO:0042428 8 0.119
regulation of cellular amine metabolic process GO:0033238 20 0.119
adenylate cyclase activating dopamine receptor signaling pathway GO:0007191 7 0.119
astrocyte differentiation GO:0048708 43 0.117
gastrin induced gastric acid secretion GO:0001698 1 0.117
negative regulation of purine nucleotide metabolic process GO:1900543 16 0.116
regulation of high voltage gated calcium channel activity GO:1901841 2 0.116
nucleotide biosynthetic process GO:0009165 78 0.116
detection of abiotic stimulus GO:0009582 60 0.116
Fly
glucose transport GO:0015758 56 0.116
purine nucleotide metabolic process GO:0006163 302 0.116
g protein coupled acetylcholine receptor signaling pathway GO:0007213 4 0.115
glycosyl compound catabolic process GO:1901658 206 0.115
regulation of ion transmembrane transporter activity GO:0032412 54 0.114
cell type specific apoptotic process GO:0097285 268 0.114
synapse organization GO:0050808 125 0.114
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.113
negative regulation of multi organism process GO:0043901 68 0.113
macromolecule catabolic process GO:0009057 281 0.113
regulation of adenylate cyclase activity GO:0045761 10 0.113
sensory perception of taste GO:0050909 18 0.113
homeostasis of number of cells GO:0048872 210 0.113
glutamate receptor signaling pathway GO:0007215 35 0.111
developmental cell growth GO:0048588 84 0.111
Fly
tissue homeostasis GO:0001894 115 0.111
leukocyte mediated immunity GO:0002443 174 0.111
protein processing GO:0016485 163 0.111
small gtpase mediated signal transduction GO:0007264 97 0.110
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.110
detection of light stimulus GO:0009583 25 0.110
Fly
regulation of secretion GO:0051046 274 0.110
positive regulation of behavior GO:0048520 40 0.110
positive regulation of kinase activity GO:0033674 155 0.110
developmental growth involved in morphogenesis GO:0060560 138 0.109
Fly
regulation of long term neuronal synaptic plasticity GO:0048169 19 0.109
negative regulation of nucleotide metabolic process GO:0045980 16 0.109
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.109
regulation of potassium ion transmembrane transporter activity GO:1901016 7 0.109
regulation of organelle organization GO:0033043 289 0.109
positive regulation of synaptic transmission glutamatergic GO:0051968 8 0.108
regulation of sodium ion transport GO:0002028 29 0.107
germ cell development GO:0007281 185 0.107
response to oxygen levels GO:0070482 62 0.107
pigmentation GO:0043473 71 0.107
negative regulation of phosphorylation GO:0042326 166 0.107
visual behavior GO:0007632 45 0.106
positive regulation of cytokine production GO:0001819 174 0.106
detection of stimulus GO:0051606 84 0.106
Fly
nucleotide metabolic process GO:0009117 332 0.105
nucleoside metabolic process GO:0009116 246 0.105
protein kinase c activating g protein coupled receptor signaling pathway GO:0007205 4 0.105
cellular ketone metabolic process GO:0042180 84 0.105
myeloid leukocyte differentiation GO:0002573 119 0.104
corticotropin releasing hormone secretion GO:0043396 2 0.104
plasma membrane organization GO:0007009 90 0.104
mapk cascade GO:0000165 281 0.104
metanephros development GO:0001656 79 0.104
diet induced thermogenesis GO:0002024 7 0.104
rhythmic process GO:0048511 174 0.102
Fly
cell adhesion GO:0007155 329 0.102
response to amine GO:0014075 16 0.102
acetylcholine secretion neurotransmission GO:0014055 2 0.102
immune response regulating signaling pathway GO:0002764 125 0.102
regulation of t cell differentiation GO:0045580 83 0.101
neuron neuron synaptic transmission GO:0007270 69 0.101
regulation of blood pressure GO:0008217 93 0.100
stem cell development GO:0048864 219 0.100
regulation of cyclic nucleotide metabolic process GO:0030799 40 0.100
negative regulation of protein metabolic process GO:0051248 282 0.100
regulation of synaptic activity GO:0060025 1 0.100
Fly
ribonucleoside metabolic process GO:0009119 245 0.100
cardiac muscle hypertrophy GO:0003300 23 0.099
regulation of calcium ion transport GO:0051924 69 0.099
negative regulation of g protein coupled receptor protein signaling pathway GO:0045744 12 0.099
positive regulation of homeostatic process GO:0032846 64 0.099
positive regulation of protein kinase activity GO:0045860 144 0.099
regulation of nucleoside metabolic process GO:0009118 130 0.098
regulation of angiogenesis GO:0045765 81 0.098
calcium ion dependent exocytosis GO:0017156 35 0.098
regulation of innate immune response GO:0045088 91 0.097
muscle adaptation GO:0043500 39 0.097
synapse assembly GO:0007416 56 0.097
regulation of proteolysis GO:0030162 164 0.096
stem cell differentiation GO:0048863 268 0.095
cranial nerve morphogenesis GO:0021602 26 0.095
embryonic organ morphogenesis GO:0048562 276 0.095
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.094
carbohydrate derivative catabolic process GO:1901136 231 0.094
semicircular canal fusion GO:0060879 1 0.094
regulation of ossification GO:0030278 112 0.094
regulation of reproductive process GO:2000241 66 0.094
purine ribonucleoside catabolic process GO:0046130 205 0.093
spermatid differentiation GO:0048515 115 0.093
regulation of cytokine production GO:0001817 266 0.093
regulation of vasculature development GO:1901342 88 0.093
regulation of synapse assembly GO:0051963 29 0.093
response to ammonium ion GO:0060359 21 0.093
regulation of synaptic transmission glutamatergic GO:0051966 19 0.093
regulation of excitatory postsynaptic membrane potential GO:0060079 41 0.092
respiratory tube development GO:0030323 167 0.091
formation of primary germ layer GO:0001704 77 0.091
spermatid development GO:0007286 108 0.090
negative regulation of synaptic transmission glutamatergic GO:0051967 4 0.090
peptide transport GO:0015833 133 0.090
innervation GO:0060384 22 0.090
negative regulation of muscle contraction GO:0045932 12 0.089
peptide secretion GO:0002790 114 0.089
positive regulation of lyase activity GO:0051349 11 0.089
defense response to bacterium GO:0042742 119 0.088
positive regulation of innate immune response GO:0045089 80 0.088
regulation of myeloid cell differentiation GO:0045637 96 0.088
organophosphate catabolic process GO:0046434 232 0.087
response to molecule of bacterial origin GO:0002237 143 0.087
regulation of fat cell differentiation GO:0045598 81 0.087
lymphocyte homeostasis GO:0002260 64 0.087
regulation of multi organism process GO:0043900 111 0.087
oligodendrocyte development GO:0014003 20 0.086
myotube differentiation GO:0014902 105 0.086
membrane hyperpolarization GO:0060081 21 0.085
regulation of cellular amino acid metabolic process GO:0006521 5 0.085
response to lipopolysaccharide GO:0032496 128 0.085
circadian behavior GO:0048512 13 0.085
Fly
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.085
positive regulation of ras gtpase activity GO:0032320 65 0.084
multi organism behavior GO:0051705 62 0.084
Fly
positive regulation of protein modification process GO:0031401 299 0.084
positive regulation of adenylate cyclase activity involved in g protein coupled receptor signaling pathway GO:0010579 3 0.083
neuron death GO:0070997 154 0.082
regulation of renal sodium excretion GO:0035813 3 0.082
mating GO:0007618 27 0.082
Fly
glycoprotein metabolic process GO:0009100 116 0.082
protein catabolic process GO:0030163 221 0.082
mesenchymal cell development GO:0014031 93 0.081
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.081
regulation of neuron death GO:1901214 134 0.081
negative regulation of intracellular signal transduction GO:1902532 167 0.081
negative regulation of phospholipase activity GO:0010519 4 0.081
dendrite development GO:0016358 115 0.081
pallium development GO:0021543 120 0.081
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.081
somatotropin secreting cell development GO:0060133 2 0.080
fertilization GO:0009566 127 0.080
regulation of osteoblast differentiation GO:0045667 67 0.080
positive regulation of the force of heart contraction by epinephrine norepinephrine GO:0001997 3 0.080
negative regulation of protein phosphorylation GO:0001933 126 0.080
ribonucleoside triphosphate catabolic process GO:0009203 199 0.079
regulation of cellular component biogenesis GO:0044087 181 0.078
striated muscle contraction GO:0006941 45 0.078
regulation of synaptic plasticity GO:0048167 87 0.078
protein localization to organelle GO:0033365 185 0.078
serotonin transport GO:0006837 11 0.078
monosaccharide transport GO:0015749 58 0.077
digestive system development GO:0055123 200 0.077
activation of mapk activity GO:0000187 59 0.077
negative regulation of neuron apoptotic process GO:0043524 92 0.076
heterocycle catabolic process GO:0046700 280 0.076
positive regulation of cardiac muscle contraction GO:0060452 2 0.076
visual perception GO:0007601 52 0.075
negative regulation of serotonin secretion GO:0014063 2 0.075
cognition GO:0050890 149 0.075
positive regulation of high voltage gated calcium channel activity GO:1901843 1 0.075
adaptive immune response GO:0002250 155 0.075
t cell differentiation in thymus GO:0033077 77 0.074
ear development GO:0043583 200 0.073
regulation of g protein activated inward rectifier potassium channel activity GO:1900128 1 0.073
organic cyclic compound catabolic process GO:1901361 295 0.073
cellular nitrogen compound catabolic process GO:0044270 280 0.073
regulation of voltage gated calcium channel activity GO:1901385 4 0.073
regulation of lipid metabolic process GO:0019216 118 0.072
leukocyte proliferation GO:0070661 172 0.071
negative regulation of cell development GO:0010721 169 0.071
renal sodium ion transport GO:0003096 2 0.071
t cell activation GO:0042110 289 0.071
intracellular protein transport GO:0006886 204 0.071
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.071
nucleoside triphosphate catabolic process GO:0009143 205 0.071
phasic smooth muscle contraction GO:0014821 8 0.070
calcium ion transport into cytosol GO:0060402 48 0.069
desensitization of g protein coupled receptor protein signaling pathway GO:0002029 5 0.069
neural crest cell differentiation GO:0014033 54 0.068

Kcna2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.232
nervous system disease DOID:863 0 0.232
central nervous system disease DOID:331 0 0.093